Jules Stein Eye Institute
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Annual Report 2009–2010 Jules Stein Eye Institute Looking Towards the Future The emblem of the Jules Stein Eye Institute is adapted from the schematic eye used by Sir Isaac Newton in his classic treatise on human vision—“Opticks”— published in 1704. The horizontal lines extending from the surface of the eye represent Newton’s concept of the major colors that are in the spectrum of light. Jules Stein Eye Institute Annual Report 2009–2010 director Bartly J. Mondino, MD faculty advisor Debora B. Farber, PhD, DPhhc managing editor Gloria P. Jurisic editors Irene Y. Chen Sara V. Nguyen photography Reed Hutchinson PhotoGraphics J. Charles Martin design Robin Weisz/Graphic Design production The Oak Company printing Marina Graphic Center ©2010, by the Regents of the University of California. All rights reserved. This report covers the period July 1, 2009, through June 30, 2010. Requests for additional copies of the publication Jules Stein Eye Institute Annual Report 2009–2010 may be sent to: Office of the Managing Editor Jules Stein Eye Institute 100 Stein Plaza, UCLA Box 957000 Los Angeles, California 90095-7000 Phone: (310) 206-7178 For more information on the Institute, see our website: www.jsei.org View the Annual Report online at: jsei.org/annual_report.htm Printed on recycled paper using soy-based inks Contents Introduction Jules Stein iii Doris Stein iii Board of Trustees iv Executive Committee v In Memoriam—Arthur L. Rosenbaum, MD vi Highlights 1 Honors 3 Research 7 Education 12 Philanthropy 16 Thank You 18 Endowed Professorships, Fellowships, and Other Funds 20 Community Outreach 23 Faculty 25 Programs 75 Patient Care Services 76 Research and Treatment Centers 77 Clinical Laboratories 81 Training Programs 83 Appendices 89 Volunteer and Consulting Faculty 90 Residents and Fellows 92 Educational Offerings 93 Research Contracts and Grants 95 Clinical Research Studies 104 Publications of the Full-Time Faculty 110 Giving Opportunities 118 The legacy of Dr. and Mrs. Jules Stein arises from their role in the 20th century as visionaries. Through brilliance and beneficence, they created a multitude of programs aimed specifically at one goal—preserving and restoring eyesight. They approached this task dauntlessly, integrating the worlds of business, medicine, and philanthropy in such a way as to enhance each and leave in trust the promise of limitless accomplishment in the advancement of eye research and treatment. The Jules Stein Eye Institute was established as a result of their philanthropy. ii Jules and Doris Stein Jules Stein Jules Stein is the foremost coordinated programs of research in the sciences benefactor in the world history related to vision, ophthalmic education, and the care of vision science and blindness of patients with eye disease. Jules Stein died in 1981, prevention. He combined his leaving a legacy of hope to the world. Through his love for music and medicine accomplishments and philanthropy, he created ever with a unique talent for analy- replenishing resources for eye research and the means sis and organization to pro- to preserve and restore sight for future generations. duce a lifetime of celebrated achievements as musician, physician, business leader, and humanitarian. Doris Stein Born in South Bend, Indiana, in 1896, Jules Stein received a PhB from the University of Chicago at age 18 Doris Stein’s purposeful, yet followed by a MD degree from Rush Medical College. richly varied life earned the After completing postgraduate studies at the University respect and affection of the of Vienna and Chicago’s Cook County Hospital, he many people who benefited began medical practice and was certified by the from her humanitarianism. American Board of Ophthalmology. Inspiring partner of her husband for more than half a A musician from an early age, he financed his education century, Doris Stein shared by playing in and leading his own band. As his reputa- with him the accomplishments of his philanthropic tion increased, he began booking other musicians for endeavors and guided his interests in ophthalmology, professional engagements, and in 1924 founded Music beginning with a visit to the New York Lighthouse for Corporation of America (MCA). Shortly thereafter, he the Blind in the late 1950s. Deeply moved, Doris Stein gave up the practice of medicine to concentrate on this urged her husband to “do something!” From that enterprise. Within 10 years, MCA represented most of passionate beginning came a broad base of programs the great name bands and corporate activities began to that catalyzed eye research. extend to representation of film stars, directors, writers, and musical artists. MCA entered the promising new Doris Stein was a major force in this vision renaissance. field of television at its inception, eventually acquiring She served as an officer and director of Research to the Universal City property, Universal Pictures, and Prevent Blindness, personally leading the appeal to other enterprises to become pre-eminent in the enter- establish more resources for investigations into eye tainment industry. diseases. She suggested that Jules Stein assume the principal role in the creation of an eye institute at Throughout his phenomenally successful career, Jules UCLA, and her unflagging enthusiasm nurtured the Stein maintained a strong interest and emotional Institute’s development as a unique provider of every investment in medicine, particularly his own field of facet of vision research and patient care. Serving as ophthalmology. In the late 1950s, urged by his wife, Trustee, she focused special attention on Institute Doris, he chose to direct his considerable talents to initiatives to combat blindness throughout the world. blindness prevention. The result was a concert of ideas She devoted her last days, until her death in 1984, to and achievements that encompassed philanthropy, the development of an expansion and companion government, and academic medicine. building for eye research. In 1989, dedication ceremo- nies were held for the Doris Stein Eye Research Center. By his efforts, Research to Prevent Blindness was created, now recognized as the world’s leading volun- With grace, vision, and meaningful action, Doris Stein tary organization in support of studies of the eye and enhanced the lives of all privileged to know her, stimu- its diseases. Jules Stein was largely responsible for the lated a cascade of progress in eye research, co-founded passage of legislation to establish the National Eye the Institute with its boundless scientific potential, Institute as a separate entity in the National Institutes and extended the miracle of sight to untold numbers of Health. Under his leadership, the Jules Stein Eye of people. Institute was founded as a multidisciplinary center for vision science. Since its establishment, the Institute has become internationally identified as the focus for Jules and Doris Stein iii Board of Trustees The Jules Stein Eye Institute Board of Trustees was established in 1977 to ensure the Institute’s orderly growth and development. The Board meets regularly during the year, with each Trustee providing his/her unique counsel. Collectively, their invaluable contri- butions have included fiscal planning for the Institute, adoption of measures to facilitate recruitment of the world’s finest vision scientists, allocation of funds for the purchase of vision research equipment, and recommendations for facilities expansion programs. Current Members Nelson C. Rising, Esq. Bartly J. Mondino, MD President and Director Chief Executive Officer Jules Stein Eye Institute Maguire Properties 1994–present 2004–present Ronald L. Olson, Esq. Partner George A. Smith, Esq. Munger, Tolles, and Olson Consultant 1995–present 1992–present Gerald H. Oppenheimer President Gerald Oppenheimer Family Foundation Katrina vanden Heuvel President Publisher and Editor Systems Design Associates The Nation Magazine 1992–present 1984–present Andrea L. Rich, PhD Retired President, Chief Executive Officer and Director Casey Wasserman Los Angeles County Museum of Art President and Executive Vice Chancellor Emerita Chief Executive Officer UCLA The Wasserman Foundation 2007–present 1998–present iv Board of Trustees Executive Committee Director, Jules Stein Eye Institute Chairman, UCLA Department of Ophthalmology Bartly J. Mondino, MD Associate Directors, Jules Stein Eye Institute Wayne L. Hubbell, PhD Gabriel H. Travis, MD Vice-Chairmen, UCLA Department of Ophthalmology Sherwin J. Isenberg, MD Arthur L. Rosenbaum, MD* Chief Administrative Officer, Jules Stein Eye Institute Jonathan D. Smith *Deceased Jules Stein Eye Institute Executive Committee: (sitting from left to right) Drs. Gabriel Travis, the late Arthur Rosenbaum, Sherwin Isenberg, and Bartly Mondino; (standing from left to right) Mr. Jonathan Smith and Dr. Wayne Hubbell. Executive Committee v In Memoriam Arthur L. Rosenbaum, MD Arthur L. Rosenbaum, MD, Chief of the Pediatric Ophthalmology and Strabismus Division and the Brindell and Milton Gottlieb Chair in Pediatric Oph- thalmology at UCLA’s Jules Stein Eye Institute, died on June 22 at Ronald Reagan UCLA Medical Center after a long illness due to complications from cancer. He was 69 years old. Dr. Rosenbaum was born on August 20, 1940, in St. Louis, Missouri. He was the eldest son of Evelyn and Dr. Harry Rosenbaum, a well-respected ophthal- Dr. Arthur Rosenbaum mologist. After earning his undergraduate degree at the University of Michigan and his medical degree at Washington University in St. Louis, he did his residency