Amitriptyline Information Booklet
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Drug and Alcohol Abuse Prevention Handbook FOREWARD
Drug and Alcohol Abuse Prevention Handbook FOREWARD Grayson College recognizes that the illicit use of drugs and/or the abuse of alcohol are a persistent health problem of major proportion affecting our society physically, mentally, and socially. Illicit drug use and /or alcohol abuse can adversely affect an individual’s personal life, safety, health, and mental and physical performance. It is the intent of GC to provide employees and students pertinent information related to illicit drug use and/or alcohol abuse in an effort to prevent such harm. GC is committed to promoting and maintaining a work and academic environment that is free from illegal alcohol and drug use and abuse, in accordance with all federal, state, and local laws. Students, employees, and visitors are prohibited from possessing, consuming, manufacturing, dispensing, or being under the influence of alcohol/illegal drugs or engaging in improper self- medication while on college property or college business. Any member of the college community who violates this policy is subject to both prosecution and punishment under federal, state, and local laws to disciplinary proceedings by the college. This alcohol/drug policy is not designed to punish people for seeking rehabilitation. All information about those individuals who voluntarily avail themselves of drug or alcohol counseling or rehabilitation will not be used as a basis for disciplinary action or be used against an individual in any way. College employees and students who violate the alcohol/drug policy shall be informed about and referred to services to assist them in determining whether they are abusing drugs and alcohol or are chemically dependent. -
Pregabalin Is First Drug Approved for Fibromyalgia
50 Pain Medicine C LINICAL P SYCHIATRY N EWS • August 2007 Pregabalin Is First Drug Approved for Fibromyalgia BY ELIZABETH MECHCATIE that are not usually painful, and that pre- cording to the revised prescribing infor- The daily dose should be administered Senior Writer gabalin may reduce the degree of pain ex- mation for pregabalin. The two studies— in two divided doses per day, starting at a perienced by patients with fibromyalgia by a 14-week double-blind placebo-controlled total daily dose of 150 mg/day, which regabalin has become the first drug binding to a specific protein within study and a 6-month randomized with- may be increased to 300 mg/day, within 1 to win approval by the Food and “overexcited nerve cells.” drawal study—found that treatment was week; the maximum dose is 450 mg/day, PDrug Administration for the man- The approval “marks an important ad- associated with a reduction in pain by vi- according to the prescribing information. agement of fibromyalgia. vance, and provides a reason for optimism sual analog scale and improvements based The most common side effects in the tri- The FDA based the approval on two for the many patients on a patient global as- als were mild to moderate dizziness and double-blind, controlled trials of approxi- who will receive pain Side effects such as sessment and on the sleepiness, blurred vision, weight gain, dry mately 1,800 patients. Data from the stud- relief ” with prega- Fibromyalgia Impact mouth, and swelling of the hands and feet ies have shown that patients with fi- balin, Dr. -
Intravenous Ketamine Alleviates Pain in a Rheumatoid Arthritis Patient with Comorbid Fibromyalgia
Case Report J Med Cases. 2018;9(5):142-144 Intravenous Ketamine Alleviates Pain in a Rheumatoid Arthritis Patient With Comorbid Fibromyalgia Ashraf F. Hannaa, b, Bishoy Abrahama, Andrew Hannaa, Micheal McKennaa, Adam J. Smitha Abstract bance, and psychological distress [4]. It is commonly regarded as the “prototypical central sensitivity syndrome” [5]. While A 49-year-old woman with rheumatoid arthritis (RA) and comorbid its etiology is not fully understood, fibromyalgia is thought to fibromyalgia presented to the clinic in extreme pain, described to be result from abnormal central pain processing and increased a 10 on an 11-point pain intensity numerical rating scale (PI-NRS). central sensitivity that results in intense, widespread pain. Fi- Because the patient also met the diagnostic criteria for fibromyalgia bromyalgia is diagnosed using the 2010 American College of and conventional medications did not achieve adequate pain control Rheumatology (ACR) criteria [6]: 1) Widespread pain index for either condition, the off-label use of intravenous (IV) ketamine (WPI) ≥ 7 and symptom severity (SS) scale score ≥ 5 or WPI was presented as an alternative therapeutic option. The patient un- 3 - 6 and SS scale score ≥ 9. 2) Symptoms have been present derwent 10 consecutive IV infusion sessions with increasing doses at a similar level for at least 3 months. 3) The patient does not of ketamine hydrochloride without any complications. Following the have a disorder that would otherwise explain the pain. 10th infusion, the patient reported that her pain was virtually non- A recent epidemiological study characterized the preva- existent (PI-NRS 0 - 1). lence of fibromyalgia among patients without pain, with re- gional pain, and with widespread pain [4]. -
Kiwiherb Valerian Oral Liquid Valerian Root Extract
PATIENT INFORMATION LEAFLET: stress and to aid sleep, exclusively based on long standing use. 2. Before you take this product DO NOT TAKE this product if you are: • Allergic to Valerian or any other ingredients in this product (see section 6) • Under 18 years of age • Pregnant or breast feeding • Taking medicines known to interact with alcohol (e.g. metronidazole) • Already taking a medicine for sleep or Kiwiherb Valerian Oral Liquid anxiety Valerian Root Extract Taking other medicines Tell your healthcare professional, e.g. a doctor or pharmacist, if you are taking any other medicines Read all of this leaflet carefully because it contains including herbal medicines or medicines that did important information for you. not require a prescription. This medicine is available without prescription. Driving and using machines However you still need to use Kiwiherb Valerian carefully to get the best results from it. This product may cause drowsiness. If affected, do not drive or operate machinery Keep this leaflet. You may want to read it again. Take Special Care with this product Ask your healthcare professional, e.g. a doctor or pharmacist, if you need more information or This product contains alcohol (45% ethanol), i.e. advice. up to 2.25 ml per 5 ml dose, (equivalent to 45 ml beer or 18.8 ml wine), and may be harmful to If the condition worsens or symptoms do not those suffering from alcoholism. improve after 2 weeks, a qualified healthcare professional, e.g. a doctor or pharmacist, should be To be taken into account in pregnant or consulted. -
Ketamine for Chronic Non- Cancer Pain: a Review of Clinical Effectiveness, Cost- Effectiveness, And
CADTH RAPID RESPONSE REPORT: SUMMARY WITH CRITICAL APPRAISAL Ketamine for Chronic Non- Cancer Pain: A Review of Clinical Effectiveness, Cost- Effectiveness, and Guidelines Service Line: Rapid Response Service Version: 1.0 Publication Date: May 28, 2020 Report Length: 28 Pages Authors: Khai Tran, Suzanne McCormack Cite As: Ketamine for Chronic Non-Cancer Pain: A Review of Clinical Effectiveness, Cost-Effectiveness, and Guidelines. Ottawa: CADTH; 2020 May. (CADTH rapid response report: summary with critical appraisal) ISSN: 1922-8147 (online) Disclaimer: The information in this document is intended to help Canadian health care decision-makers, health care professionals, health systems leaders, and policy-makers make well-informed decisions and thereby improve the quality of health care services. While patients and others may access this document, the document is made available for informational purposes only and no representations or warranties are made with respect to its fitness for any particular purpose. The information in this document should not be used as a substitute for professional medical advice or as a substitute for the application of clinical judgment in respect of the care of a particular patient or other professional judgment in any decision-making process. The Canadian Agency for Drugs and Technologies in Health (CADTH) does not endorse any information, drugs, therapies, treatments, products, processes, or services. While care has been taken to ensure that the information prepared by CADTH in this document is accurate, complete, and up-to-date as at the applicable date the material was first published by CADTH, CADTH does not make any guarantees to that effect. CADTH does not guarantee and is not responsible for the quality, currency, propriety, accuracy, or reasonableness of any statements, information, or conclusions contained in any third-party materials used in preparing this document. -
Neurological Complications of Nitrous Oxide Abuse
Katherine Shoults, MD Case report: Neurological complications of nitrous oxide abuse A patient who presented with limb paresthesia and B12 deficiency was eventually diagnosed with subacute combined degeneration neuropathy secondary to nitrous oxide abuse. Case data ABSTRACT: A 34-year-old female ary to nitrous oxide (“laughing gas”) A 34-year-old female presented with with a history of alcohol and crystal abuse that had affected B12 activa- a 2-week history of progressive bilat- methamphetamine abuse presented tion. The patient was continued on eral limb paresthesia and tenderness, to the emergency department with B12 therapy, neurology follow-up as well as an inability to balance. She limb paresthesia and difficulty walk- was arranged, and addiction coun- had been well previously, although ing. At a primary care visit a week seling services were recommended. she did have a history of alcohol and earlier her progressive neurological Unfortunately, the patient was lost crystal methamphetamine abuse. She compromise had been viewed in the to follow-up after discharge from the had abstained from crystal metham- context of anemia and she was start- hospital. Physicians should be aware phetamine for 5 years and from alco- ed on daily B12 injections. Further that nitrous oxide is easy to acquire hol for 2 months. She was working as a investigations in hospital revealed in the form of commercially available care aid and denied using illegal drugs diminished proprioception, hyperal- cartridges or whipped cream canis- currently, but reported she had been gesia with pinprick and temperature ters called “whippits” and abuse of inhaling nitrous oxide (“laughing tests, a wide-based high-steppage nitrous oxide is increasingly com- gas”) for 6 months, with an escalation gait, elevated levels of B12 and ho- mon. -
SAD.002 Alcohol and Drugs
ALCOHOL AND DRUG POLICY Southern Oregon University is committed to promoting an environment that supports the health and well-being of every member of the campus community. Since drug and alcohol abuse can seriously impair an individual’s personal and academic functioning, the University helps campus members make responsible decisions about drugs and alcohol. It is Southern’s obligation, therefore, to provide pertinent drug and alcohol information, educational opportunities, prevention-related activities, individual support and referral services, and enforcement of University rules regarding the use of alcohol and illegal drugs. In keeping with this policy and the intent of Public Law 101-226, Section 22: Drug-Free Schools and Campuses, it is our obligation and responsibility to inform you of the health risks associated with the use of various illicit drugs, nicotine, and the abuse of alcohol. Please note that any substance used through needle-sharing increases the risk of contracting AIDS and hepatitis B. Controlled Substances: Type of Drug and Possible Health Risks 1. Stimulants – speed up action of central nervous system • Amphetamines (speed). Hallucinations; heart problems; malnutrition; dependency; paranoid psychosis; death. Affects fetal development. • Cocaine (coke, crack) — Classified as a narcotic. Confusion; depression; convulsions; damaged nasal membranes; lung lesions; dependency; coma; paranoid psychosis; death. Affects fetal development. • MDMA (ecstasy). Short-term: euphoria; dehydration; loss of inhibition. Long-term: danger to cognitive learning and memory impairment. 2. Depressants – relax central nervous system • Barbiturates (downers). Tranquilizers and methaqualone (ludes). Confusion; loss of coordination; tolerance; dependency; seizures; coma; death. • Especially dangerous in combination with alcohol. 3. Cannabis – alters perception and mood • Marijuana and hashish. -
Pubmed/19078481?Dopt=Abstract
Efficacy of tramadol in treatment of pain in fibromyalgia. - Pu... https://www.ncbi.nlm.nih.gov/pubmed/19078481?dopt=Abstract PubMed Format: Abstract J Clin Rheumatol. 2000 Oct;6(5):250-7. Efficacy of tramadol in treatment of pain in fibromyalgia. Russell IJ1, Kamin M, Bennett RM, Schnitzer TJ, Green JA, Katz WA. Author information Abstract An outpatient, randomized, double-blind, placebo-controlled clinical trial was conducted to evaluate the efficacy and safety of tramadol in the treatment of the pain of fibromyalgia syndrome. One hundred patients with fibromyalgia syndrome, (1990 American College of Rheumatology criteria), were enrolled into an open-label phase and treated with tramadol 50-400 mg/day. Patients who tolerated tramadol and perceived benefit were randomized to treatment with tramadol or placebo in the double-blind phase. The primary efficacy outcome measurement was the time (days) to exit from the double-blind phase because of inadequate pain relief, which was reported as the cumulative probability of discontinuing treatment because of inadequate pain relief. One hundred patients entered the open-label phase; 69% tolerated and achieved benefit with tramadol. These patients were then randomized to continue tramadol (n = 35) or convert to a placebo (n = 34) during a 6-week, double-blind treatment period. The Kaplan-Meier estimate of cumulative probability of discontinuing the double blind period because of inadequate pain relief was significantly lower in the tramadol group compared with the placebo group (p = 0.001). Twenty (57.1%) patients in the tramadol group successfully completed the entire double-blind phase compared with nine (27%) in the placebo group (p = .015). -
Alcohol Hangover Headache
Headache ISSN 0017-8748 C 2007 the Authors doi: 10.1111/j.1526-4610.2006.00694.x Journal compilation C 2007 American Headache Society Published by Blackwell Publishing Expert Opinion Alcohol Hangover Headache Case History submitted by Randolph W. Evans, MD Expert opinion submitted by Christina Sun, MD; Christine Lay, MD Key words: alcohol hangover headache, migraine (Headache 2007;47:277-279) In his 1954 first novel, “Lucky Jim,” Sir Kingsley she has no ill effects. She is healthy with no history of Amis describes the delayed effects of drinking port significant headaches. on the titular history lecturer upon awakening in the morning. “Dixon was alive again. Consciousness was QUESTIONS upon him before he could get out of the way; not for What is the prevalence and cause of alcohol hang- him the slow, gracious wandering from the halls of over headache (AHH)? What are the latency, features, sleep, but a summary, forcible ejection. ... The light and duration of the headache? Is the risk of develop- did him harm, but not as much as looking at things ment of AHH related to the type or amount of alcohol did; he resolved, having done it once, never to move consumed? How can you distinguish between AHH his eyeballs again. A dusty thudding in his head made and migraine triggered by alcohol? Are there any ef- the scene before him beat like a pulse. ...he sat up a fective interventions or treatments for AHH? little, and what met his bursting eyes roused to a frenzy the timpanist in his head.” EXPERT COMMENTARY Alcohol hangover, or “veisalgia,” is a well-known CASE and common phenomenon that generally occurs af- A few hours after drinking 3 glasses of any type ter heavy consumption of alcohol. -
Problematic Use of Nitrous Oxide by Young Moroccan–Dutch Adults
International Journal of Environmental Research and Public Health Article Problematic Use of Nitrous Oxide by Young Moroccan–Dutch Adults Ton Nabben 1, Jelmer Weijs 2 and Jan van Amsterdam 3,* 1 Urban Governance & Social Innovation, Amsterdam University of Applied Sciences, P.O. Box 2171, 1000 CD Amsterdam, The Netherlands; [email protected] 2 Jellinek, Department High Care Detox, Vlaardingenlaan 5, 1059 GL Amsterdam, The Netherlands; [email protected] 3 Amsterdam University Medical Center, Department of Psychiatry, University of Amsterdam, P.O. Box 22660, 1100 DD Amsterdam, The Netherlands * Correspondence: [email protected] Abstract: The recreational use of nitrous oxide (N2O; laughing gas) has largely expanded in recent years. Although incidental use of nitrous oxide hardly causes any health damage, problematic or heavy use of nitrous oxide can lead to serious adverse effects. Amsterdam care centres noticed that Moroccan–Dutch young adults reported neurological symptoms, including severe paralysis, as a result of problematic nitrous oxide use. In this qualitative exploratory study, thirteen young adult Moroccan–Dutch excessive nitrous oxide users were interviewed. The determinants of problematic nitrous oxide use in this ethnic group are discussed, including their low treatment demand with respect to nitrous oxide abuse related medical–psychological problems. Motives for using nitrous oxide are to relieve boredom, to seek out relaxation with friends and to suppress psychosocial stress and negative thoughts. Other motives are depression, discrimination and conflict with friends Citation: Nabben, T.; Weijs, J.; van or parents. The taboo culture surrounding substance use—mistrust, shame and macho culture— Amsterdam, J. Problematic Use of frustrates timely medical/psychological treatment of Moroccan–Dutch problematic nitrous oxide Nitrous Oxide by Young users. -
Amitriptyline (Elavil): Important Patient Information
What is most important to remember? If you have questions: Strong Internal Medicine • You must check to make sure that it is safe for you to take Ask your doctor, nurse or pharmacist for amitriptyline with all of your other more information about amitriptyline medicines and health problems (Elavil®). • Do not start any new medications, over-the-counter drugs or herbal remedies without talking to your doctor • Contact your prescriber If your symptoms or health problems do not get any better or they become worse • This medicine comes with an Strong Internal Medicine extra patient fact sheet called a 601 Elmwood Avenue Medication Guide. Read it with Ambulatory Care Facility, 5th Floor care. Read it again each time this Rochester, NY 14642 Phone: (585) 275 -7424 medicine is refilled Amitriptyline (Elavil®): • If you think there has been an Visit our website at: Important Patient Information www.urmc.rochester.edu/medicine/ - overdose, call your poison control general-medicine/patientcare/ center or get medical care right away What does amitriptyline (Elavil®) do? What side effects could occur with amitriptyline What are some things that I need to be aware of when • It belongs to a class of medications called tricyclic (Elavil®)? taking amitriptyline (Elavil®)? antidepressants (TCAs). It works by increasing the • Hard stools (constipation) • Tell your doctor or pharmacist if you are allergic to amitriptyline, any other medicines, foods, or substances amounts of certain natural substances in the brain that • Dizziness, feeling sleepy are needed -
Doxepin (Sinequan)
8/31/2017 Doxepin Uses, Side Effects & Warnings - Drugs.com doxepin (Sinequan) Generic Name: doxepin (Sinequan) (DOX e pin) Brand Name: What is doxepin (Sinequan)? This medication guide provides information about the use of doxepin (Sinequan or other generic names) to treat depression or anxiety. Silenor is another brand of doxepin that is not covered in this medication guide. Doxepin is a tricyclic antidepressant that affects chemicals in the brain that may be unbalanced. Doxepin (Sinequan or other generic name) is used to treat symptoms of depression and/or anxiety associated with alcoholism, psychiatric conditions, or manic-depressive conditions. Doxepin may also be used for purposes not listed in this medication guide. What is the most important information I should know about doxepin (Sinequan)? You should not take doxepin if you have glaucoma or problems with urination. Do not use if you are allergic to doxepin or to similar antidepressants. Do not use this medicine if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine. Some young people have thoughts about suicide when first taking an antidepressant. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor. Do not give this medicine to anyone under 18 years old without the advice of a doctor. Doxepin is not approved for use in children. What should I discuss with my healthcare provider before taking doxepin (Sinequan)? You should not use doxepin if you are allergic to it, or if you have: glaucoma; urination problems; or an allergy to similar antidepressants such as amitriptyline, amoxapine, clomipramine, desipramine, imipramine, nortriptyline, protriptyline, or trimipramine.