H1N1 Influenza (“Swine Flu”)
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Influenza Virus Infections in Humans October 2018
Influenza virus infections in humans October 2018 This note is provided in order to clarify the differences among seasonal influenza, pandemic influenza, and zoonotic or variant influenza. Seasonal influenza Seasonal influenza viruses circulate and cause disease in humans every year. In temperate climates, disease tends to occur seasonally in the winter months, spreading from person-to- person through sneezing, coughing, or touching contaminated surfaces. Seasonal influenza viruses can cause mild to severe illness and even death, particularly in some high-risk individuals. Persons at increased risk for severe disease include pregnant women, the very young and very old, immune-compromised people, and people with chronic underlying medical conditions. Seasonal influenza viruses evolve continuously, which means that people can get infected multiple times throughout their lives. Therefore the components of seasonal influenza vaccines are reviewed frequently (currently biannually) and updated periodically to ensure continued effectiveness of the vaccines. There are three large groupings or types of seasonal influenza viruses, labeled A, B, and C. Type A influenza viruses are further divided into subtypes according to the specific variety and combinations of two proteins that occur on the surface of the virus, the hemagglutinin or “H” protein and the neuraminidase or “N” protein. Currently, influenza A(H1N1) and A(H3N2) are the circulating seasonal influenza A virus subtypes. This seasonal A(H1N1) virus is the same virus that caused the 2009 influenza pandemic, as it is now circulating seasonally. In addition, there are two type B viruses that are also circulating as seasonal influenza viruses, which are named after the areas where they were first identified, Victoria lineage and Yamagata lineage. -
Keeping Your Gut in Check Healthy Options to Stay on Tract Your Digestive System Is Busy
May 2017 National Institutes of Health • Department of Health and Human Services • newsinhealth.nih.gov Inside News: 3 Bronchitis vs. Pneumonia... 4 Eating Habits and Disease... Spanish Health Materials... Human Genome Keeping Your Gut in Check Healthy Options to Stay on Tract Your digestive system is busy. What you eat can help or When you eat something, your hurt your digestive system, and food takes a twisty trip that influence how you feel. “Increas- starts with being chewed up ing fiber is really important for and ends with you going to constipation,” says Chang. “Most the bathroom. A lot happens in Americans do not eat a lot of between. The health of your gut fiber so you have to gradually plays a key role in your overall increase the fiber in your diet. health and well-being. You can Otherwise you might get gas make choices to help your body and more bloating, and won’t stay on tract. stick with [the changes].” Your digestive, or Chang says you should eat at gastrointestinal (GI), tract is a least 20–30 grams of fiber a day long, muscular tube that runs for constipation. You can spread from your mouth to your anus. out your fiber in small amounts It’s about 30 feet long and throughout the day. Start with works with other parts of your small servings and gradually digestive system to break food increase them to avoid gas, and drink down into smaller bloating, and discomfort. molecules of nutrients. The Try to eat fruits and vege- blood absorbs these and carries them Chang, a GI expert at the University tables at every meal. -
Call to Action: the Dangers of Influenza and COVID-19 in Adults
Call to Action The Dangers of Influenza and COVID-19 in Adults with Chronic Health Conditions October 2020 Experts urge all healthcare professionals to prioritize influenza vaccination to help protect adults with chronic health conditions during the COVID-19 pandemic The recommendations in this Call to Action are based on discussions from an Call to Action August 2020 Roundtable convened by the National Foundation for Infectious The Dangers of Influenza Diseases (NFID). The multidisciplinary and COVID-19 in Adults with group of subject matter experts Chronic Health Conditions explored the risks of co-circulation and co-infection with influenza and SARS-CoV-2 viruses in adults with chronic Overview health conditions from the perspective While every influenza (flu) season is unpredictable, of their specialized areas of medicine the 2020-2021 season is characterized by an and discussed strategies to protect unprecedented dual threat: co-circulation of these vulnerable populations. influenza and the novel coronavirus (SARS-CoV-2) that causes COVID-19. Moreover, there is concern Experts agreed that higher levels of that co-circulation and co-infection with influenza influenza vaccination coverage during and COVID-19 viruses could be especially harmful, the 2020-2021 influenza season could particularly among adults at increased risk of reduce the number of influenza-related influenza-related complications. hospitalizations, helping to avoid Influenza poses serious health risks to adults unnecessary strain on the US healthcare with certain chronic health conditions including system during the COVID-19 pandemic, heart disease, lung disease, and diabetes. The so that healthcare facilities have the increased risk of influenza-related complications capacity to provide care to patients includes the potential exacerbation of underlying with COVID-19. -
Influenza (PDF)
INFLUENZA Outbreaks of influenza, or “flu”, typically occur every winter. Colds may occur at any time of year with seasonal peaks occurring in fall and spring. Influenza is a respiratory illness usually caused by infection with one of two influenza viruses – influenza A or influenza B. Outbreaks of influenza (flu) typically occur every winter. Influenza is characterized by an abrupt onset of fever, chills, headache, body aches, and lack of energy accompanied by respiratory symptoms, most frequently cough and sore throat. Most people are largely recovered in one week, although many feel fatigued for several weeks. Serious complications of flu, such as pneumonia, however, can occur, especially if the body’s defenses are weakened by age or disease. Influenza is spread by inhaling the influenza virus which is usually carried on tiny, invisible water droplets in the air generated by coughs and sneezes. Hand-to-hand contact as well as contact with infected secretions on a hard surface may also cause transmission of the virus. Each year influenza viruses change and new vaccines are made to combat the particular strains that are expected to cause illness that year. The flu vaccine may reduce the chance of getting the flu by 60-80%, and lessen the severity of illness in the person who does get the flu. According to the Centers for Disease Control (CDC), everyone 6 months or order should get a yearly flu vaccine. The following people are at high risk for complications of flu and are especially urged to get vaccinated: Individuals with chronic heart or lung problems that have required regular medical follow-up or hospitalization during the last year. -
Bronchiolitis
Bronchiolitis What is bronchiolitis? Bronchiolitis is a viral infection of the lungs that usually affects infants. There is swelling in the smaller airways or bronchioles of the lung, which causes coughing and wheezing. Bronchiolitis is the most common reason for children under 1 year old to be admitted to the hospital. What are the symptoms of bronchiolitis? The following are the most common symptoms of bronchiolitis. However, each child may experience symptoms differently. Symptoms may include: Runny nose or nasal congestion Fever Cough Changes in breathing patterns (wheezing and breathing faster or harder are common) Decreased appetite Fussiness Vomiting What causes bronchiolitis? Bronchiolitis is a common illness caused by different viruses. The most common virus causing this infection is Respiratory Syncytial Virus (RSV). However, many other viruses can cause bronchiolitis including: Influenza, Parainfluenza, Rhinovirus, Adenovirus, and Human metapneumovirus. Initially, the virus causes an infection in the upper airways, and then spreads downward into the lower airways of the lungs. The virus causes swelling of the airways. Mucus is also produced in the airways. This narrowing of the airways can make it difficult for your child to breath, eat, or nurse. How is bronchiolitis diagnosed? Bronchiolitis is usually diagnosed on the history and physical examination of the child. Antibiotics are not helpful in treating viruses and are not needed to treat bronchiolitis. Because there is no cure for the disease, the goal of treatment is to make your child comfortable and to support their symptoms. This treatment may include suctioning to keep the airways clear, extra oxygen if the blood oxygen levels are low, or hydration if your child is not able to feed well. -
Avian Influenza Outbreaks in the United States Q&A
USDA Questions and Answers: Avian Influenza Outbreaks in the United States April 2015 Avian Influenza in the United States Q. Does highly pathogenic avian influenza currently exist in the United States? A. Since mid-December 2014, there have been several ongoing highly pathogenic avian influenza (HPAI) H5 incidents along the Pacific, Central and Mississippi Flyways. Cases in wild birds, captive wild birds, backyard poultry or commercial poultry have been reported in Arkansas, California, Iowa, Idaho, Kansas, Minnesota, Missouri, Montana, North Dakota, Nevada, Oregon, Utah, South Dakota, Washington, Wisconsin and Wyoming. Details are available on the APHIS website. The HPAI strains detected recently in these flyways are H5N2, H5N8 and H5N1, but primarily H5N2 in turkey flocks. Q. Can people catch these highly pathogenic avian influenza strains that are being detected in these outbreaks? A. CDC considers the risk to people from these HPAI H5 viruses in wild birds, backyard flocks, and commercial poultry, to be low. No human infections with these viruses have been detected at this time, however, similar viruses have infected people. It’s possible that human infections with these viruses may occur. While human infections are possible, infection with avian influenza viruses in general are rare and – when they occur – these viruses have not spread easily to other people. These reports of H5-infected wild birds and poultry in the United States do not signal the start of a pandemic. Q. How is USDA dealing with these HPAI outbreaks? A. The United States has the strongest AI surveillance program in the world so that the food supply remains safe. -
COPD (Chronic Obstructive Pulmonary Disease)
COPD (Chronic Obstructive Pulmonary Disease) A difficult problem explained in simple language. Introduction The normal lung Lung facts What is COPD? How does COPD damage your health? How can I tell if I am developing COPD? How can we tell if you are developing COPD? What can you do to help yourself? What can we do to help you? Conclusion INTRODUCTION So you want to find out more about the illness that we call COPD. It may be that your doctor has raised some concerns that you might have this condition but has not had a chance to explain what it is. You may have seen something in the press about COPD which describes symptoms that you have been getting such as cough, phlegm and breathlessness or you may have a loved one who is developing these symptoms and you are concerned to find out what the cause is. Make sure you read all the way through to the end of this description and we hope that you will have a much better understanding. The normal lung. As we travel through the voice box (larynx) into the main windpipe (trachea) we find the airways that we pass through get smaller and smaller with increasing numbers of branches until the tiniest tubes open into bubbles whose walls consist of a very fine membrane. These bubbles are arranged in bunches like grapes around which is a lace work of very fine blood vessels. In the healthy lung, when air reaches these bubbles (alveoli), oxygen passes readily through the bubble membrane into the blood stream. -
COVID-19 Infection Versus Influenza (Flu) and Other Respiratory Illnesses
American Thoracic Society PATIENT EDUCATION | INFORMATION SERIES PATIENT EDUCATION | INFORMATION SERIES COVID-19 Infection versus Influenza (Flu) and Other Respiratory Illnesses SARS-CoV-2 is the virus that causes the COVID-19 infection. You can be ill with more than one virus at the same time. As the SARS-CoV-2 virus pandemic continues, influenza and other respiratory infections can also be present in the community. Respiratory infections may present with similar symptoms and all can spread from person to person. It is hard to tell which virus or bacteria is causing a person’s illness based on symptoms alone. At times testing is needed to see which virus(es) or bacteria are present. These tests usually involve getting a nose and/or throat swab sample, as most of these viruses are present in large amounts in the back of the nose and throat. There is still a lot to learn about the COVID-19 infection and research is ongoing. You can be ill with more than one virus at the same time. COVID-19). COVID vaccine supplies are limited but When multiple viruses are present the risk of developing increasing. The states control who is eligible and where severe disease increases. Severe disease usually involves vaccines are given. difficulty breathing and getting oxygen into your body. The influenza vaccine covers Flu A and B strains expected Risk factors for severe illness are shown in the table. in each year’s flu season. Getting a flu vaccine each year How are COVID-19 and other respiratory can help protect you and reduce your risk of severe viruses spread? illness. -
The Effect of Corticosteroids on Mortality of Patients with Influenza
Ni et al. Critical Care (2019) 23:99 https://doi.org/10.1186/s13054-019-2395-8 RESEARCH Open Access The effect of corticosteroids on mortality of patients with influenza pneumonia: a systematic review and meta-analysis Yue-Nan Ni1, Guo Chen2, Jiankui Sun3, Bin-Miao Liang1* and Zong-An Liang1 Abstract Background: The effect of corticosteroids on clinical outcomes in patients with influenza pneumonia remains controversial. We aimed to further evaluate the influence of corticosteroids on mortality in adult patients with influenza pneumonia by comparing corticosteroid-treated and placebo-treated patients. Methods: The PubMed, Embase, Medline, Cochrane Central Register of Controlled Trials (CENTRAL), and Information Sciences Institute (ISI) Web of Science databases were searched for all controlled studies that compared the effects of corticosteroids and placebo in adult patients with influenza pneumonia. The primary outcome was mortality, and the secondary outcomes were mechanical ventilation (MV) days, length of stay in the intensive care unit (ICU LOS), and the rate of secondary infection. Results: Ten trials involving 6548 patients were pooled in our final analysis. Significant heterogeneity was found in all outcome measures except for ICU LOS (I2 =38%,P = 0.21). Compared with placebo, corticosteroids were associated with higher mortality (risk ratio [RR] 1.75, 95% confidence interval [CI] 1.30 ~ 2.36, Z =3.71,P = 0.0002), longer ICU LOS (mean difference [MD] 2.14, 95% CI 1.17 ~ 3.10, Z =4.35,P < 0.0001), and a higher rate of secondary infection (RR 1.98, 95% CI 1.04 ~ 3.78, Z = 2.08, P = 0.04) but not MV days (MD 0.81, 95% CI − 1.23 ~ 2.84, Z =0.78,P = 0.44) in patients with influenza pneumonia. -
COMMON COLD & INFLUENZA (Cont.)
COMMON COLD & INFLUENZA (cont.) COMMON COLD & INFLUENZA Common colds are mild infections of the nose and What is the treatment? throat, which are very common in young children While there is medication available, most health (and in adults who are around them), and are caused care providers suggest rest and plenty of fluids. To by many different viruses. Usually the viral illness see if there is bacterial infection in addition to the causes some combination of stuffy nose, runny viral infection, a healthcare provider should nose, sore throat, cough, runny eyes, ear fluid and evaluate a child who has a high fever, persistent fever. cough, or earache. Because of a possible association with Reye’s Syndrome (i.e., vomiting, Influenza (the flu) is also caused by a virus (e.g., liver problems and coma), salicylate-containing influenza-A, influenza-B) and causes symptoms of products (i.e., aspirin) are not recommended for fever, headache, sore throat, cough, muscle ache control of fever. and fatigue. Most people with influenza feel too ill to attend childcare. How can the spread of these diseases be prevented? Occasionally, the common cold or influenza can be Influenza vaccine is the primary method of complicated by a bacterial infection such as an ear preventing influenza and its severe complications. infection, sinus infections, or pneumonia. These The vaccine should be given annually beginning at complications can be treated with appropriate 6 months of age. Two doses should be given the antibiotics after evaluation by their health care first year the child receives the influenza vaccine. provider. Annual influenza vaccination is recommended for Who gets these diseases? all children aged 6 months through age 18 with Anyone can. -
Pneumonia Information for Patients Introduction You Have Been Admitted to Hospital for Treatment of Pneumonia
Oxford University Hospitals NHS Trust Pneumonia Information for patients Introduction You have been admitted to hospital for treatment of pneumonia. This leaflet will give you information so that you understand a bit more about the illness and know what to expect during your stay. What is pneumonia? Pneumonia is an inflammation of the lung tissue, usually as a result of an infection. How severe your symptoms are will depend upon a number of factors. Some people with pneumonia can be treated and cared for in their own homes with antibiotic tablets, but if you have a more severe case of pneumonia you may need a stay in hospital with intravenous antibiotics (given through a drip). How do you get pneumonia? You may have breathed in some bacteria, viruses, or other germs. If you are normally healthy, a small number of germs usually do not matter. They will be trapped in your sputum (phlegm) and killed by your immune system. Sometimes, however, germs can multiply and cause lung infections. This is more likely to happen if you are already in poor health, if you are frail or elderly, if you have a chest disease or if you have a low immunity to infection. If you are aware you have a low immunity then it is advisable to speak to your health care practitioners about what might be done to prevent you getting pneumonia again in the future. However, even healthy people can develop pneumonia. page 2 What are the symptoms? Typical symptoms of pneumonia are: • a cough • a fever (high temperature) • sweating • shivering • being off your food • feeling generally unwell. -
Cdc Pandemic Influenza Questions and Answers 10-20-2017
CDC PANDEMIC INFLUENZA QUESTIONS AND ANSWERS • What is an influenza pandemic? o An influenza pandemic is a global outbreak of a new influenza A virus that is very different from current and recently circulating human seasonal influenza A viruses. Pandemics happen when new (novel) influenza A viruses emerge which are able to infect people easily and spread from person to person in an efficient and sustained way. • Where do pandemic influenza viruses come from? o Different animals—including birds and pigs—are hosts to influenza A viruses that do not normally infect people. Influenza A viruses are constantly changing, making it possible on very rare occasions for non-human influenza viruses to change in such a way that they can infect people easily and spread efficiently from person to person • How do influenza A viruses change to cause a pandemic? o Influenza A viruses are divided into subtypes based on two proteins on the surface of the virus: the hemagglutinin (H) and the neuraminidase (N). There are 18 different hemagglutinin subtypes and 11 different neuraminidase subtypes (H1 through H18 and N1 through N11). Theoretically, any combination of the 18 hemagglutinins and 11 neuraminidase proteins are possible, but not all have been found in animals and even fewer have been found to infect humans. o Influenza viruses can change in two different ways one of which is called “antigenic shift” and can result in the emergence of a new influenza virus. Antigenic shift represents an abrupt, major change in an influenza A virus. This can result from direct infection of humans with a non- human influenza A virus, such as a virus circulating among birds or pigs.