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EAPC ONLUS Abstracts of the 9th Congress of the European Association for Palliative Care (EAPC) Résumés du 9ème Congrès de l’Association Européenne de Soins Palliatifs Aachen, Germany, 8–10 April 2005 Aix la Chapelle, Allemagne, 8–10 avril 2005 ABSTRACTS RÉSUMÉS EAPC Instituto Nazionale Dei Tumori Via Venezian 1 20133 Milano ITALIA Tel: +39 02 2390 3390. Fax: +39 02 2390 3393. email: [email protected] www.eapcnet.org Published by Hayward Medical Communications, a division of Hayward Group plc, Rosalind Franklin House, The Oaks, Fordham Road, Newmarket CB8 7XN, UK. Publié par Hayward Medical Communications, une division d’Hayward Group plc, Rosalind Franklin House, The Oaks, Fordham Road, Newmarket CB8 7XN, Royaume-Uni. Cover picture: View of the Hague by Pieter Gerard Vertin (1819–1893)/ Bridgeman Art Library Couverture: View of the Hague par Pieter Gerard Vertin (1819–1893)/ Bridgeman Art Library Abstracts of the 9th Congress of the European Association for Palliative Care, Aachen 2005 i Résumés du 9ème Congrès de l’Association Européenne de Soins Palliatifs, Aix la Chapelle 2005 ii Abstracts of the 9th Congress of the European Association for Palliative Care, Aachen 2005 Résumés du 9ème Congrès de l’Association Européenne de Soins Palliatifs, Aix la Chapelle 2005 Scientific Committee CONTENTS Stein Kaasa, Norway, Chair Lukas Radbruch, Germany, Co-Chair Eduardo Bruera, USA Friday 8 April 2005 David Clark, UK Franco De Conno, Italy ABSTRACTS OF INVITED LECTURES Marilène Filbet, France AND ORAL PRESENTATIONS 3 Katalin Hegedus, Hungary Phil Larkin, Ireland ABSTRACTS OF POSTERS 17 Friedemann Nauck, Germany Sheila Payne, UK Saturday 9 April 2005 David Praill, UK Advisory Board to the ABSTRACTS OF INVITED LECTURES Scientific Committee AND ORAL PRESENTATIONS 47 Julia Addington-Hall, UK Johann Baumgartner, Austria ABSTRACTS OF POSTERS 60 Snezana Bosnjak, Croatia William Breitbart, USA Sunday 10 April 2005 Bert Broeckaert, Belgium Cristian Juul Busch, Denmark ABSTRACTS OF INVITED LECTURES Nathan Cherny, Israel AND ORAL PRESENTATIONS 91 Nessa Coyle, USA Kathleen Foley, USA ABSTRACTS OF POSTERS 105 Carl Johan Fürst, Sweden Paul Glard, Australia Index Richard Hain, UK Geoffrey Hanks, UK BY AUTHOR 135 Jo Hockley, UK Christoffer Johansen, Denmark Martina Kern, Germany Eberhard Klaschik, Germany Jacek Luczak, Poland Marco Maltoni, Italy Sebastiano Mercadante, Italy Tatsuya Morita, Japan Monika Müller, Germany Katalin Muszbek, Hungary Mildred Solomon, USA Juan Manuel Nuñez Olarte, Spain Margaret O’Connor, Australia Antonio Pascual Lopez, Spain Jose Pereira, Canada Joseph Porta I Sales, Spain Sylvia Sauter, Sweden René Chaerer, France Per Sjøgren, Denmark Jan Tjernsward, Sweden Floria Strasser, Switzerland Corry Van Tol, the Netherlands Charles F Von Gunten, USA Annette Welshman, UK Furio Zucco , Italy Abstracts of the 9th Congress of the European Association for Palliative Care, Aachen 2005 iii Résumés du 9ème Congrès de l’Association Européenne de Soins Palliatifs, Aix la Chapelle 2005 iv Abstracts of the 9th Congress of the European Association for Palliative Care, Aachen 2005 Résumés du 9ème Congrès de l’Association Européenne de Soins Palliatifs, Aix la Chapelle 2005 FRIDAY 8 APRIL 8 FRIDAY ABSTRACTS OF INVITED LECTURES, ORAL PRESENTATIONS AND POSTERS 8 APRIL 2005 Abstracts of the 9th Congress of the European Association for Palliative Care, Aachen 2005 Résumés du 9ème Congrès de l’Association Européenne de Soins Palliatifs, Aix la Chapelle 2005 Invited lectures and oral presentations 2 Abstracts of the 9th Congress of the European Association for Palliative Care, Aachen 2005 Résumés du 9ème Congrès de l’Association Européenne de Soins Palliatifs, Aix la Chapelle 2005 Invited lectures and oral presentations Abstract number: 1 Abstract number: 3 Abstract number: 5 Presentation type: Invited Presentation type: Invited Presentation type: Invited Poster number: Poster number: Poster number: Curriculum for Palliative Nurse Education “Palliative care – an international Opioid Pharmacogenetics – does it perspective – the observatory”. matter clinically? Phil Larkin, Dept. Palliative Medicine, Galway, IRELAND, Françoise Porchet, Centre Hospitalier Carlos Centeno, Hospital Los Montalvos, Lukas Radbruch, Department of Palliative Universitaire Vaudois CHUV, Lausanne, Salamanca, Spain Medicine, University of Aachen, Germany SWITZERLAND In this session we are going to explain the four The recommendations of the expert working As part of the EAPC TASKFORCE Strategy on lines of work of the EAPC Task Force on group of the European Association for Palliative APRIL 8 FRIDAY Education, a taskforce was identified to prepare development of Palliative Care in Europe: Care (EAPC) has evaluated the level of evidence guidelines that would provide a framework for of the available opioids. Summarizing this palliative nurse education in Europe. This a) Literature review and summary of any evaluation, the efficacy of opioids is well document, recently published by the EAPC, published work about the development of proven. Morphine and other opioids of the offers a plan of action for centres who wish to palliative care in each of the countries. This WHO-steps 2 and 3 are effective for the pursue the development of palliative nurse job is mainly carried out by Javier Rocafort treatment of cancer pain. education and highlights key considerations, with the help of Anthony Greenwood. With the increasing number of available skills and competencies and identifies the b)International survey to boards of the National opioids and application forms individual supportive and inhibitory factors to sound Associations of Palliative Care, seeking differences in the efficacy of these opioids have education for nurses. opinions about the general situation, led to the opinion that the indication for In this workshop, a brief overview of the key strengths and opportunities for palliative care opioids and specific application routes should recommendations will be given, followed by in their country. be decided for the individual patient in the the opportunity for audience participants to c) International survey to an expert within each specific setting. The rationale for this share their experiences of organizing, country, to gather concrete data about the differentiated approach is found in individual facilitating and evaluating education initiatives, state of palliative care service delivery and differences in the efficacy of different opioids, as well as sharing the reality of education for organization in the country. differences in the side effect profile, efficacy nurses within the European context. d)Research on the national Directories of with different pain syndromes such as Services, whether published, printed or neuropathic pain or breakthrough pain, and online. differences with organ dysfunction or failure Abstract number: 2 Also, the present state of the study and our such as renal or hepatic insufficiency. Presentation type: Invited upcoming plans will be explained. With the introduction of new slow release Poster number: application forms in the last years differences in the side effect profile have been postulated. Less Palliative care – an international Abstract number: 4 constipation with transdermal fentanyl, lower perspective: the work of the International Presentation type: Invited incidence of neurotoxic side effects with Observatory on End of Life Care Poster number: oxycodone and lower risk of respiratory depression with buprenorphine have been David Clark, International Observatory on End Opioids pharmacogenetics – does it postulated. Buprenorphine might be of Life Care, Lancaster, GREAT BRITAIN matter clinically? advantageous in renal impairment, as part of the drug is excreted through bile and gut. Founded at Lancaster University in 2003, the Pal Klepstad, Dept. Intensive Care Medicine, Fentanyl or methadone could offer advantages International Observatory on End of Life Care is Trondheim, NORWAY for patients with hepatic impairment. The non- the first ever research and development project opioid activities of some opioids, especially the to concentrate on the comparative analysis of Variability of opioid efficacy caused by genetic reuptake inhibition of monoaminergic hospice and palliative care around the world. variations has been recognized for several years. transmitters and the NMDA-antagonism, have The Observatory is unique in being focussed The most established clinical significant genetic been considered as advantages of tramadol and solely on end of life care and in its emphasis on variability is related to the CYP2D6 enzyme methadone for neuropathic pain. a social science perspective. The aims of the metabolizing codeine to morphine. Slow Using evidence-based criteria, these theses Observatory are: 1. To provide clear and metabolizers of codeine produce less morphine must remain under discussion. It remains accessible research-based information on and have a less pronounced analgesic effect unclear, whether data from animal pain models hospice and palliative care provision in the from codeine. Genetic variability has also been or healthy volunteers can be transferred to international context, incorporating shown to influence on the efficacy of opioids cancer patients. An individually adapted opioid ethnographic, historical and ethical for moderate to severe cancer pain such as therapy, taking pain syndrome, receptor status perspectives as well as health care systems morphine. This genetic variability may be and patient metabolism