ALUMNI VOLUME XXX, NO. 2 – ISSUE 2, 2020 CONNECTION A PUBLICATION FOR MEDICAL ALUMNI AND FRIENDS

For everything you do. We Thank You. –The Alumni Association

CLASS OF 2020 CELEBRATES MATCH DAY pg 4

CARDIOLOGY FELLOW RECEIVES MICHENER AWARD pg 7

CLEVELAND CLINIC RESPONDS TO PANDEMIC pg 8 CONTENTS ALUMNI VOLUME XXX, NO. 2 – ISSUE 2, 2020 CONNECTION A PUBLICATION FOR MEDICAL ALUMNI AND FRIENDS

A MESSAGE FROM THE ALUMNI BOARD PRESIDENT BOARD OF DIRECTORS EXECUTIVE COMMITTEE Dear Alumni, Dale Shepard, MD, PhD, FACP I President Welcome to our redesigned Alumni Richard Lang MD, MPH I President Elect Connection! The Alumni Relations Leo Pozuelo, MD I Vice President of Communications team and I hope that you will enjoy Christine Booth, MD I Vice President of Membership the new look, aimed at making the Conrad H. Simpfendorfer, MD, FACS I Immediate Past-President publication easy to navigate. (Please note that some photos, without masks, SPECIALTY DIRECTORS were taken before March 1, 2020.) Tom Abelson, MD Octavian Ioachimescu, MD, PhD In this issue, we highlight Cleveland Rebecca Bagley, MD Jonathan Kaplan, MD Clinic’s response to the COVID-19 pandemic and our Alumni Christine Booth, MD Richard Kaplon, MD Adam Brown, MD Alice Kim, MD Awards. We also report on our Lerner College of Medicine Ravi Chittajallu, MD Leonard Krajewski, MD graduates’ highly successful Match Day results. (Please see Kevin El-Hayek, MD Richard Lang, MD, MPH pages 8-11, 7, and 4-6.) Peter Evans, MD, PhD Mark Licht, MD Kaushik Ghosal, PhD Asma Moheet, MD Of course, the news dominating all of our personal and pro- Bradley Gill, MD Lydia Parker, MD fessional lives for many months now concerns the coronavirus Jeffrey Goshe, MD Mauricio Perilla, MD Mark Grove, MD Marc Pohl, MD pandemic. I am proud of, and amazed by, Cleveland Clinic’s Andrew Healy, MD Gina Robinson, MD, FAAP powerful and proactive response, including converting the Darlene Holden, MD Khaldoun Tarakji, MD, MPH atrium of our new Health Education Campus into the 1,000-bed Karen Jacobs, DO Andrew Vassil, MD Adriana Ioachimescu, MD, PhD, FACE Eric Weiss, MD Hope Hospital in only three short weeks, a massive team effort. (Please see page 11.) COMMITTEE MEMBERS

Because of the early actions of Ohio’s Governor Mike DeWine, Leonard Calabrese, DO I Centennial Wall Project Director and his collaboration with experts including Cleveland Clinic Gary Dworkin, MD I Philanthropy Committee Chair CEO and President Tom Mihaljevic, MD, we have seen far fewer Khaldoun Tarakji, MD, MPH I Alumni Connect Project Director patients with COVID-19 in our hospital system than originally anticipated. In fact, Cleveland Clinic sent a medical team to assist overwhelmed hospitals in other locations. This, too, Alumni Connection is a publication of the Cleveland Clinic Alumni shows the cooperative spirit of our Cleveland Clinic family. Association, produced in conjunction with Development Communications, for medical alumni and friends by the Philanthropy Institute. (Please see pages 8-9.) Mindy Stroh I Senior Director Our Centennial plans are fluid right now because of the Tara Samstag I Associate Director pandemic. We will update you when we know more. Katie Eurich I Assistant Director And one final note: We, the Alumni Association, could not Elaine DeRosa Lea I Editor, Alumni Connection be prouder of our alumni than we are right now. We honor Orenge Creative Group I Design you for your dedication, skill, compassion, and personal sacrifice during this global pandemic. We teach many things ON THE COVER at Cleveland Clinic, but heroism arises only from within. ALUMNI VOLUME XXX, NO. 2 – ISSUE 2, 2020 CONNECTION Thank you for all that you do, and please stay safe. The Alumni Association thanks each A PUBLICATION FOR MEDICAL ALUMNI AND FRIENDS and every one of you for your service Sincerely, during this global pandemic. Our cover For everything you do. illustration is based on a T-shirt design We Thank You. –The Alumni Association that honors caregivers and expresses our thoughts well: “There is a Hero in All of Us.” (Please see page 6 for Dale Shepard, MD, PhD more details about the shirt.)

2 ALUMNI CONNECTION – ISSUE 2, 2020 CONTENTS Contents

Putting Patients First in a Pandemic Cleveland Clinic sent medical teams to other hospitals caring for COVID-19 patients. Learn where they went and the personal experience of one team member, alumnus Pravin George, DO. See how the Health Education Campus’ main building was transformed into Hope Hospital, and read comments by Dr. Mihaljevic on the pandemic. pgs 8-11

Cleveland Clinic Research Features The Center for Global and Emerging Pathogens Research is established; Cleveland Clinic doctors save a patient with a rare immunological disorder; study shows Lerner College of Medicine is achieving its mission, the Anatomy Lab offers the latest digital technology; the BRIDGE study helps and more. pgs 12-18 patients prevent disease. (Photo taken prior to March 1, 2020.) pgs 16-20

DEPARTMENTS AWARDS FROM THE ARCHIVES CONTACTS Cardiology fellow Amit Goyal, MD, PhD, received Where it all began: Cleveland Clinic’s first building Sandra Hong, MD, honored as a Woman the Michener Award, and Kavya Kommaraju, MD, and how it changed through the years. Plus, of Note; Dr. Howarth turns 100, and much Internal Medicine intern, the GL-1 Award. pg 7 Cleveland Clinic’s family ties. pgs 24-27 more. pgs 32-35

NEWS PHILANTHROPY IN MEMORIAM Alumnus featured on the cover of Vogue Thailand; News on the CARES Act. pg 29 Kidney Transplant Pioneer alumni couple weds on the rooftop of Satoru Nakamoto, MD, Dies at 92. pg 39 Cleveland Clinic. pgs 21-22

A publication for Cleveland Clinic medical alumni and friends. – clevelandclinic.org/alumni 3 EDUCATION Cleveland Clinic MATCH DAY: Lerner College of Medicine On March 20, like medical students across the nation, CCLCM students celebrated Match Day, an annual event when graduates learn where they will go for their residencies. This year’s Match Day was unique because of the pandemic. The gathering at the CWRU Tinkham Veale University Center was quieter and calmer. Faculty members spoke from Tinkham Veale or their own homes. Students gathered with their families, in small groups, or waited at their computers for an email revealing their results. However, students and their loved ones still celebrated. Faculty members felt overwhelming pride. People connected. The coronavirus couldn’t take that away. —From Insight/Lerner College of Medicine Class of 2020 Janet Adegboye Lestella Bivens Robert Borden University of University of Chicago Stanford University Maryland-Mercy Medical Center Programs Medical Center PEDIATRICS THORACIC SURGERY INTERNAL MEDICINE Johns Hopkins Hospital ANESTHESIOLOGY

William (Alex) Harry Choi Katharina Cantrell Hospital of the Clore-Gronenborn Cleveland Clinic University of PA Children’s National ORTHOPAEDIC INTERNAL MEDICINE Medical Center SURGERY PEDIATRICS

Albert Feeny Caroline Franke Suresh Garudadri University of UPMC Medical Stanford University California Education Programs San Francisco PSYCHIATRY INTERNAL MEDICINE INTERNAL MEDICINE

4 ALUMNI CONNECTION – ISSUE 2, 2020 EDUCATION

Brittany Goldstein Brett Graham Nikhil Gupta Northwestern Vanderbilt University University of Chicago McGaw/NMH/VA Medical Center Medical Center PSYCHIATRY NEUROLOGY INTERNAL MEDICINE

Cameron Severine Kako Kaitlin Keenan Beau Hilton Case Western/ Rush University Vanderbilt University University Hospitals Medical Center Medical Center Cleveland Medical NEUROLOGY INTERNAL Center MEDICINE/ABIM NEUROLOGY RESEARCH PATH

Ann Kim Anne Kim Erika Lampert Johns Hopkins Hospital of the Cleveland Clinic Hospital University of PA OBSTETRICS AND INTERNAL MEDICINE OBSTETRICS AND GYNECOLOGY GYNECOLOGY

Diane Libert John McAfee Appledene Osbourne Stanford University Cleveland Clinic University of Programs PATHOLOGY California Davis PATHOLOGY Medical Center INTERNAL MEDICINE

Radhika Rastogi Navin Sabharwal Elizabeth Shay Children’s Hospital - University of Indiana Philadelphia California Irvine University SOM PEDIATRICS UROLOGY OTOLARYNGOLOGY

Continued on page 6

A publication for Cleveland Clinic medical alumni and friends. – clevelandclinic.org/alumni 5 EDUCATION

Shehryar Christina Snider Robert Unger (Sherry) Sheikh Vanderbilt University Case Western/ Wake Forest Medical Center Metro-Health System Baptist Med Center INTERNAL MEDICINE INTERNAL MEDICINE GENERAL SURGERY Massachusetts General Hospital RADIOLOGY DIAGNOSTIC

Lamont Wilkins David Xiong Wenda Ye Johns Hopkins UPMC Medical Vanderbilt University Hospital Education Medical Center UROLOGY INTERNAL MEDICINE OTOLARYNGOLOGY Case Western/ University Hospitals DERMATOLOGY

Emily Zhang Jessica Zhang Cleveland Clinic UCLA Medical Center OTOLARYNGOLOGY INTERNAL MEDICINE Congratulations, Class of 2020!

Alumni Association Celebrates House Staff Officers, Trainees The Alumni Association showed its appreciation of Cleveland Clinic’s House Staff Association and medical trainees during Resident Appreciation Week in April by giving “There is a Hero in All of Us” T-shirts to the 16 house officers and Panera gift cards to the 1,300 trainees. Half of all proceeds from sales of these shirts, which were created by GV Art and Design, benefit caregiver support funds at both Cleveland Clinic and University Hospitals.

Cleveland Clinic sponsors one of the nation's largest graduate medical education programs, with 108 training programs approved by the Accreditation Council for Graduate Medical Education (ACGME) and 92 special fellowship programs. ■

6 ALUMNI CONNECTION – ISSUE 2, 2020 EDUCATION Cardiology Fellow Receives Michener RESIDENT Award for Educational Podcast Kavya Kommaraju, MD, Receives GL-1 Award

1st photo: Cardiac amyloid discussion: Daniel Ambinder and Jackie Zimmerman (top left), Carine Hamo (top right), Heather Kagan and Yuxuan Wang (bottom panels), Amit Goyal (middle). 2nd photo: The first CardioNerds recording. From left, Daniel Ambinder, Heather Kagan, Amit Goyal. (Photo taken prior to March 1, 2020.)

Cleveland Clinic cardiology fellow atmosphere,” Dr. Goyal says. Amit Goyal, MD, has a story to tell. Every episode ends with “What Actually, he has quite a few—as do Makes My Heart Flutter,” in which colleagues and listeners around the a listener shares a recent success The Alumni Association congrat- world, who share them through his story. “Given the unacceptably high ulates Kavya Kommaraju, MD CardioNerds Podcast. rate of burnout in medicine, we (PGY-1, Internal Medicine) on For this innovative medical educa- believe that giving voice to each becoming the 33rd annual tion podcast, Dr. Goyal was named other’s successes—clinical or GL-1 Award Recipient. The the 2020 recipient of the Dr. William nonclinical—is important,” he says. award, established in 1987, and Roxanna Michener Award for the “Flutter moments” have included recognizes excellence. Development of Leadership in Medical work-life balance, obtaining free Dr. Kommaraju was an intern Humanities and the Arts. The award medication for a patient, and the on the inpatient Cardiology support helps him develop and joys of seeing a patient through a service of Cleveland Clinic expand the podcast, launched in successful heart transplant. staff member and alumnus January, with his co-hosts at Johns “We aim to make this show Ann Gage, MD, (CARD’17, Hopkins, cardiology fellows Carine inclusive and promote diversity CCM’18), who praised her E. Hamo, MD, Daniel Ambinder, by attempting to achieve a gender maturity, efficiency, interpersonal MD, and resident Heather Kagan, balance of voices on the show,” skills and knowledge. She also MD. Dr. Goyal was chief resident at he says. “We believe that hearing wrote, “She excels at providing Johns Hopkins before coming to leading women cardiologists could clear plans and appropriate levels Cleveland Clinic for his fellowship. help inspire a generation of learners of information for patients and “I am so fortunate and honored into a field that traditionally has their families. She demonstrated to receive the Michener Award,” been less attractive for women.” a sophisticated knowledge of the Dr. Goyal says. “It opens the doors The Michener Award helps offset physiology at hand and was able in many ways.” the cost of production, promotion and to communicate this at an The podcast helps listeners stay archiving the podcasts, Dr. Goyal says. appropriate level. To do this current in cardiovascular medicine. “We are grateful to Dr. Reza Manesh requires both excellent socializa- Along with an online medical educa- at Johns Hopkins for his encourage- tion and superb intelligence.” tion platform, it takes beginners to ment and support in getting us Dr. Gage added that “an an advanced level and advanced started. I thank David Nemer, my intern who researches and listeners back to basics. Each podcast cardiology co-fellow at Cleveland continually educates herself on centers on one topic, followed by Clinic, for giving me the idea to apply small points of data is unique. adjunct episodes with experts. “We for the award, and, from the bottom Kavya is a shining star whose seek to humanize the field of cardiol- of my heart, I thank the Alumni excellent performance should ogy with easy-to-follow discussions, Association,” Dr. Goyal says. “Their be acknowledged.” ■ professional diversity, and a jovial support makes our hearts flutter.” ■

A publication for Cleveland Clinic medical alumni and friends. – clevelandclinic.org/alumni 7 COVID-19

Putting Patients First … Anywhere In the early days of the outbreak, Cleveland Clinic reached out to health systems in the hardest-hit areas of the country to provide assistance. Soon It really felt like it was a after, hundreds of Cleveland Clinic caregivers offered their services. Twelve calling. We’ve all gone into physicians and 15 nurses provided front-line reinforcements at New a profession where we have York-Presbyterian hospitals in New York City, the epicenter of the pandemic chosen to go help those in the United States. A group of nurses did the same at the Henry Ford Health System in Detroit. Caregivers also came to the aid of others in need in need. around the world. In England, where Cleveland Clinic London will open in —Lauren Lowery, PRN, an ICU nurse 2021, Cleveland Clinic physicians, nurses and pharmacists stepped up to from Cleveland Clinic’s main campus assist with the National Health Service’s pandemic response. And in the who went to New York-Presbyterian United Arab Emirates, home to Cleveland Clinic Abu Dhabi, caregivers from the U.S. also helped battle COVID-19. ■ —Cleveland Clinic Magazine

8 ALUMNI CONNECTION – ISSUE 2, 2020 COVID-19

Alumnus Helps Fight Pandemic in His Old Neighborhood

Nearly 60 Cleveland Clinic alumni went to New York and Michigan to help overwhelmed hospitals care for patients with COVID-19. Among them was Pravin George, DO (IM’10, N’13, NVS’14), a neuro-intensive care physician who, on learning he was assigned to New York-Presbyterian Hospital, realized

Dr. George at New York- he’d be back in the neighborhood where he grew up. Presbyterian Hospital

“I didn’t know till the night before, in a conference call, where I would be working,” he says. “It turned out to be the hospital where my grandfather went when he had a stroke.” Even before the team was assembled, he had considered helping out. Seeing the news of Pravin George, MD, far right, and the medical team in New York (Photos are courtesy of Dr. George) New York hit hard by the pandemic reminded him of the tragic events 4 and 2. He was concerned about were dealing with an extremely of Sept. 11, 2001. “I was just a leaving them and also about being dire situation. It was good that college student then and wanted to exposed to a dangerous virus, we were there.” do something. But I had no training but he knew that there was a Not only was he driven to then. I felt helpless.” critical need for his skills and help colleagues, “but also, in Knowing that he and the other those of the four other ICU the back of mind, I thought, team members had Cleveland physicians on the team. ‘We haven’t had a surge, but Clinic’s backing gave him confi- “Only very few people in the Cleveland is a decent-sized city. dence, he says, and, everything country can do what we do,” he If something happens, and all else fell into place. “All of a sudden, says. “It was a once-in-a-lifetime of a sudden, we have a surge I found I had a week off in my opportunity.” in Northeast Ohio, by that time, schedule,” he says. “And my ICU On arriving at New York I’d be back and could help our group let me know that if I needed Presbyterian, he learned that the own teams. I could share with more time, they would help me out. patient population had exploded. them what worked or what It was exactly the right time.” “We had to get on the ground, didn’t. All five of us would be Even so, it was a tough decision. assess the situation, and put able to do that.’” He and his wife, Ava George, DO everything together while admission Dr. George says he is grateful (FM’13), a family practitioner at rates were climbing into the hun- for his experience of helping Cleveland Clinic Fairview Hospital, dreds per night,” he says. “A lot of where the need was greatest at had just had a baby boy. The couple the docs were really tired, and the the height of a pandemic. “This also has three daughters, ages 6, nursing ratio was very bad. They was part of my life’s mission.” ■

A publication for Cleveland Clinic medical alumni and friends. – clevelandclinic.org/alumni 9 COVID-19

Dr. Tom Mihaljevic Comments on the Pandemic

Tom Mihaljevic, MD, CEO and President of Cleveland Clinic, recently was interviewed by Cleveland Clinic Magazine about the pandemic. Here are just a few of his thoughts, which concern the long-term effects on healthcare and what the pandemic reveals about Cleveland Clinic as an organization:

What good things do you see coming A crisis can bring clarity. Is there out of the pandemic that will anything that you understand more reshape healthcare? clearly today than you did before the pandemic? There are many silver linings. This country always finds a way to come out of every crisis stronger What has become very clear is that Cleveland and smarter. When this is over, digital technology Clinic is a special organization. Our caregivers in healthcare is going to become more prevalent. are our heroes. They’re engaged. They’re Healthcare will be more integrated. And there’s compassionate. And they’re doing exceptional PHI-1854916_04-22-20_080_ST.dng PHI-1854916_04-22-20_079_ST.dng PHI-1854916_04-22-20_078_ST.dng PHI-1854916_04-22-20_077_ST.dng going to be a substantially greater allocation of workPHI-1854916_04-22-20_076_ST.dng throughout this pandemic. We’ve been in research dollars, because the understanding of a fortunate position as one of the better-prepared the importance of research is now more firmly organizations in healthcare, and therefore our established. In essence, I believe that all of the caregivers have had opportunities to extend aspects of healthcare that we were seeking to a helping hand for patients in need in improve for years will now improve in much New York City, Detroit, London and Abu Dhabi. more accelerated ways, just because of the I’ve never been more proud of the work that needs uncovered during this pandemic. we do. This crisis, if anything, has reinforced my belief that we have a special mission, and that we’re part of an extraordinary organization not only with a wonderful heritage, but with a very bright future. ■

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6 _1854916_Fink_04-22-20_ST Detroit to Departing Nurses During Avon at Mihaljevic P_PHI_Dr. COVID-19 Hope Hospital In April, Cleveland Clinic completed a temporary conversion of the main building of the Health Education Campus of Case Western Reserve University and Cleveland Clinic into a surge hospital to be used if needed during the COVID-19 pandemic. The facility, called Hope Hospital, initially includes 327 patient beds for low-acuity COVID-19 patients. Cleveland Clinic has been observing the COVID-19 pandemic nationally and internationally and studying its effects to guide our approach. The temporary hospital is one part of Cleveland Clinic’s strategy to be fully prepared to meet the needs of our a thousand-bed-capability facility community during this rapidly that rivals fixed buildings in many It’s been amazing to parts of the country.” evolving situation. watch clinical leaders and The conversion was accomplished In World War I, a group of in less than a month. Cleveland doctors, nurses and operations, construction, “It’s been a heroic effort by support staff led by surgeon George design and nursing teams hundreds of people,” Edmund S. W. Crile, MD, was the first American all come together in a unit to arrive in France, where Sabanegh Jr., MD, President of very short window of Main Campus and Regional they established a field hospital. Hospitals, said in an April 15 Cleveland Clinic was founded on time and literally build a article on Cleveland Clinic’s this same model of teamwork. thousand-bed-capability “This gets back to our fundamen- Consult QD website. “There’s facility that rivals fixed tals,” Dr. Sabanegh said, “which is really no precedent for us doing buildings in many something this big this quickly. to identify a need and be innovative It’s been amazing to watch clinical in how you address it. To use the parts of the country. basic principles of what’s right in leaders and operations, construc- —Edmund S. Sabanegh Jr., MD, medical care and solve a problem.” ■ tion, design and nursing teams President of Main Campus all come together in a very short —Sources: Cleveland Clinic’s Newsroom and Regional Hospitals window of time and literally build and Consult QD

Share Your News Your colleagues are interested in hearing your news. Please drop us a line at: ClevelandClinic.org/AlumniNewsletter

A publication for Cleveland Clinic medical alumni and friends. – clevelandclinic.org/alumni 11 RESEARCH New Center Aims to Broaden Understanding of Emerging Diseases

Cleveland Clinic Lerner Research Institute on the main campus in Cleveland

12 ALUMNI CONNECTION – ISSUE 2, 2020 RESEARCH

Cleveland Clinic is establishing the Center for Global and Emerging Pathogens Research to broaden understanding of emerging pathogens—ranging from Zika virus to SARS-CoV-2 (which causes COVID-19)—and to expedite critically needed treatments and vaccines.

The new center, supported in In addition, researchers will closely March on a network-based large part by philanthropy, will span collaborate with the newly estab- prediction model using artificial Cleveland Clinic’s Lerner Research lished Cleveland Clinic BioRepository, intelligence to identify targets for Institute and the soon-to-open drug developers at Lerner Research drug repurposing in coronaviruses. Cleveland Clinic Florida Research Institute’s Center for Therapeutics Other projects are uncovering and Innovation Center (FRIC) in Discovery, and the Populations how SARS-Cov-2 causes disease. Port St. Lucie, Florida. A team of Health Research Center. A clinical trials committee will renowned experts will lead the center Cleveland Clinic is ramping up identify and prioritize the most to further research of diseases such research related to COVID-19. A promising therapies. as COVID-19, highly pathogenic research registry of nearly 10,000 In partnership with Cleveland influenza, Dengue fever, AIDS and patients is collecting data from Clinic Florida, the new center also Zika virus-related conditions. patients tested at Cleveland Clinic, will conduct research at the Florida Leveraging Cleveland Clinic’s and there are plans to integrate the Research and Innovation Center robust research infrastructure, the data with the electronic medical building, an advanced research center will uncover the scientific record. Researchers will mine the facility anticipated to open mechanisms of how SARS-Cov-2 data to inform other studies. this summer. ■ and other pathogens cause disease. Researchers published findings in —Cleveland Clinic Media Relations

Cleveland Clinic Florida Research and Innovation Center in Port St. Lucie, Florida (Photos provided by Cleveland Clinic Media Relations)

A publication for Cleveland Clinic medical alumni and friends. – clevelandclinic.org/alumni 13 RESEARCH The Lerner College of Medicine is achieving its mission

Based on a 10-year follow up of “The goals were to discover what Four of the graduates went on to the first Cleveland Clinic Lerner the first class has accomplished earn another degree following medical College of Medicine graduating since graduation and if they are school. Advancing their education class, the class of 2009, we involved in research activities, as wasn’t necessarily a surprise. Rather, are achieving our mission of we would hope they are,” says what surprised Dr. Greenfield and developing physician investigators. Dr. Greenfield. her team was that the graduates The infographic below shows, Our graduates continue to work earned another degree while they among other things, that more hard and achieve. The number of were busy with their residencies, than 70 percent of the class of research projects and publications fellowships and medical practice. 2009 report a dedicated research is high, and the graduates’ Because the literature suggests effort, and half reported protected dedication to education, in terms that a physician’s first faculty research time. of teaching, is impressive. appointment doesn’t happen until Jessica Greenfield, PhD, a “It’s heartening to see how 10 years after medical school post-doctoral fellow in medical graduates are promoting and paying graduation, Dr. Greenfield and her education and a clinical instructor forward the kind of educational team waited until the first class of medicine with CCLCM, experiences they had here,” says was 10 years out before conducting conducted the alumni study. Dr. Greenfield. this follow up. ■

TEN YEARS AFTER GRADUATION The Class of 2009 75% RESEARCH COMPLETED RESEARCH EFFORT FELLOWSHIP – At least 25% received EDUCATION NIH funding – 50% have received DUAL non-NIH funding support DEGREES – 50% have protected 14 More than 18 research time earned after ADVANCED – 60% have served as medical school 250 DEGREES 4 papers PI or co-PI published – 1 patent with faculty appointments including associate dean, vice chair, assistant 65% professor, instructor, and adjunct. RESEARCHER ENGAGEMENT More than Basic Science Research 20% PEER-REVIEWED SCHOLARSHIP Translational Research 25% 90% Clinical Research 50% intend to More than 83% as first More than 93% as pursue additional Outcomes Research 20% or senior author on contributing author on research peer-reviewed paper peer-reviewed paper Health Services Research 15% opportunities

14 ALUMNI CONNECTION – ISSUE 2, 2020 RESEARCH Dr. Vince Receives $4 million DOD research grant D. Geoffrey Vince, PhD (Staff’11), Stokes Cleveland Veterans Affairs Chair, Department of Biomedical Medical Center will have ultrasound Engineering has received a four-year, of their carotid arteries. In tandem, $4 million grant from the Department a new program, the Compositional of Defense (DOD) to study the Analysis System by Machine (CASM) relationship between the composition learning algorithm, will create three- of carotid artery plaque and the dimensional reconstructions of the risk of a future cerebrovascular plaques. The investigators will test accident (CVA). the algorithm’s ability to determine Ischemic stroke makes up nearly the degree of stenosis and predict 90% of CVAs. Although the degree the precise plaque composition. of the blockage and size of the The study also will seek plaque are important, Dr. Vince,who associations between diabetes and holds the Lois Kennedy Endowed the noninvasive ultrasonic measure Chair in Biomedical Engineering and of carotid plaque composition. Applied Therapeutics, believes that Diabetes is a significant risk factor D. Geoffrey Vince, PhD composition is a better measure of for atherosclerotic carotid stenosis (Photo by Stephen Travarca) plaque vulnerability and stroke risk. —patients may have plaque that is Currently, carotid artery plaque softer and more pliable, increasing significant for the healthcare and composition is determined using the likelihood of an ischemic stroke wellbeing of veterans,” comments magnetic resonance imaging. (compared to non-diabetic patients Dr. Vince. “We know that about He and his research team will with similar amounts of plaque). 20% of veterans have diabetes, combine ultrasound and a new The investigators believe CASM and smoking rates are especially machine learning algorithm to may enable clinicians to better high among vets—both of which better, and noninvasively, assess monitor patients who are taking contribute to CVA risk. We are plaque composition. medications for diabetes and assess excited to collaborate with our In this study, 1,500 patients their effects on the composition of colleagues from the VA to help with carotid artery stenosis from carotid artery plaque. provide care to this population.” ■ Cleveland Clinic and the Louis “This research is especially —Cleveland Clinic Lerner Research Institute

Cleveland Clinic has a journal of medicine? Yes, we do! For nearly 90 years, Cleveland Clinic Journal of Medicine (CCJM) has published practical, clinical information on internal medicine, cardiology and related fields. Every month, CCJM reaches more than 125,000 physicians in print, and it also is available free at ccjm.org. The journal, which consistently appears near the top of readership rankings, fulfills a core Cleveland Clinic mission of educating those who serve.

Please contact CCJM to request an email with the table of contents each month.

A publication for Cleveland Clinic medical alumni and friends. – clevelandclinic.org/alumni 15 FEATURE

Doctors Credit Medical Training in Treating Patient with Rare Disorder

In April 2017, Charlotte Garrison of At her first appointment in South Bend, Indiana, was life-flighted January 2017, he diagnosed the to Cleveland Clinic, where she had illness as mucous membrane emergency tracheostomy surgery to pemphigoid, or cicatricial help her breathe. For close to a year pemphigoid. “She has a relatively before that, the 68-year-old woman rare autoimmune blistering disease had struggled with a rare immune subtype,” he says. “For Charlotte, disorder that caused sores in her the trachea and airway mucosa nose and mouth. Now, they were were affected, and severe involve- suffocating her. ment of the airway can end up Charlotte’s symptoms first ap- being life-threatening. In addition, peared in 2016, including severe the skin can be affected, and she fatigue that led the kindergarten had that, as well.” teacher to early retirement. She was This autoimmune disease causes Charlotte Garrison referred to Anthony Fernandez, MD, scarring and permanent tissue celebrates her 70th birthday PhD (DMP’11), Director of Medical damage. “When the upper airway and Inpatient Dermatology at is involved, this scarring can prevent Cleveland Clinic, who specializes in air from getting to the lungs,” he followed by “a drug cocktail” to treating autoimmune and inflamma- says, “so we were very aggressive calm the inflammation and a few tory diseases affecting the skin. in starting medications.” more operations to release scarring Dr. Fernandez and Matt Vasievich, and treat the upper airway stenosis, MD, PhD (D’17), then a medical Dr. Bryson says. I think that our experience, resident, identified a cancer drug, “I think that our experience, rituximab, that could control her collaboration and aggressiveness in collaboration and symptoms. Dr. Vasievich went to treatment were critical to Charlotte’s aggressiveness in treatment great lengths to obtain her insurance eventual recovery,” Dr. Fernandez were critical to Charlotte’s company’s approval. Still, there says. “She is now doing fantastic.” wasn’t time for the drug to take eventual recovery. She is Dr. Fernandez and Dr. Vasievich effect before Charlotte’s condition credit their Cleveland Clinic training now doing fantastic. suddenly deteriorated, leading to with helping them diagnose and a lifesaving tracheostomy by Paul —Anthony Fernandez, MD, PhD, treat patients like Charlotte. Director of Medical and Inpatient Bryson, MD, Section Head of “I could not be happier with my Dermatology at Cleveland Clinic Laryngology in Cleveland Clinic’s training here,” Dr. Fernandez says. Head & Neck Institute. This was “We have one of the best dermato-

16 ALUMNI CONNECTION – ISSUE 2, 2020 pathology fellowships in the world. Dr. Vasievich, now on staff at an We’re an international referral IHA medical dermatology clinic in center, so in training, we get as southeast Michigan, says he is Dr. Anthony Fernandez much breadth in the field as we grateful for his years at Cleveland will see in practicing. Both our Clinic. “Someone once told me dermatology and pathology clinics that when you get busy, you don’t are outstanding. As a fellow, I rise to the occasion. You fall to the could walk down the hall to consult level of your training. I think about internationally known experts who artists like Michelangelo, whose are editors of major textbooks. It students went out and developed is a very friendly and productive their own style but were influenced environment to practice in, which by their training. Dr. Fernandez is why I wanted to stay.” is a fantastic medical dermatologist. Dr. Fernandez’s duties include You learn from great mentors teaching and mentoring 12 like him. Now, after three years, dermatology residents and three I’m developing my own style as dermatopathology fellows a year. a physician.” ■ Dr. Matthew Vasievich

A publication for Cleveland Clinic medical alumni and friends. – clevelandclinic.org/alumni 17 FEATURE

Digital Tools Enhance Anatomy Education

Within the Toby Devan Lewis Digital Suite inside the Samson Pavilion, first-year students are discovering the intricacies of the human body by interacting with computer-generated simulations and virtual anatomical models. The digital suite comprises four rooms: virtual reality, ultrasound simulation, radiology and multi-user touch interface.

VIRTUAL REALITY these modules directly from their RADIOLOGY Facilitated by Jennifer McBride, smart phones, tablets or computers Stuart Morrison, MD, Clinical PhD, Associate Professor of via an app. Professor of Radiology, guides Surgery and Director of Virtual students through a variety of Anatomy, students use an Oculus ULTRASOUND SIMULATION imaging studies. Using the Agfa Rift virtual reality headset to Guided by Shetal Shah, MD, IMPAX client, a digital radiology examine digital anatomical models Assistant Professor of Radiology, imaging system, students can review within the context of a clinical students learn anatomy by a vast collection of patient X-rays, case. The anatomical models were practicing ultrasound-related CT scans and MRIs. produced by Zygote. Dr. McBride examinations on a Simbionix U/S created the educational content Mentor. The high-fidelity male and MULTI-USER TOUCH INTERFACE to accompany the anatomical female manikins, which represent This station, facilitated by Richard models. Students have access a human torso, head and neck, can Drake, PhD, Professor of Surgery to a collection of clinical case simulate a wide variety of virtual and Director of Anatomy, combines modules that cover bodily patients with both normal and a Sectra Table, which is a two-di- systems and also can access pathologic findings. mensional touchscreen, and actual

18 ALUMNI CONNECTION – ISSUE 2, 2020 (Photos taken prior to March 1, 2020.) Page 18-19 photo series: Students benefit from high-tech tools in the Toby Devan Lewis Digital Suite in the Samson Pavilion. Page 19, Top photo: Jennifer McBride, PhD, Associate Professor of Surgery and Director of Virtual Anatomy, facilitates the virtual reality station within the Toby Devan Lewis Digital Suite. Page 19, Bottom photo: Richard Drake, PhD, Professor of Surgery and Director of Anatomy, Inclusion of these uses a Sectra Table to teach anatomy. four modalities gives human imaging data from both the also attend anatomy sessions in the the students an Visible Human Project from the U.S. CCLCM Anatomy Laboratory, where National Library of Medicine and there are demonstrations of dissec- opportunity to view and clinical imaging studies. The students tion on human donors. “The students interact with complex can view 3-D renderings in multiple seem to enjoy learning anatomy ways. Using a virtual knife, they can from both technology and human anatomical structures strip away layers of the body and donors,” Dr. McBride says. in unique ways. even perform virtual dissection. Drs. McBride and Drake are “Inclusion of these four modalities conducting a longitudinal retention —Jennifer McBride, PhD, gives the students an opportunity Associate Professor of Surgery and to measure retention at the end of Director of Virtual Anatomy to view and interact with complex the first, second and third years and anatomical structures in unique then compare the results with ways,” says Dr. McBride, noting that previously published data. ■ digital technology isn’t a replace- —Excerpted from January 2020 Insight, ment for the most valuable learning Cleveland Clinic Lerner College of Medicine resource, the human donor. Students (Photos by Yu Kwan Lee)

A publication for Cleveland Clinic medical alumni and friends. – clevelandclinic.org/alumni 19 FEATURE Building THE BRIDGE PROJECT

Participants were attracted by the offer of YMCA gym memberships, as well as one-on-one patient education, medical appointments and progress assessments for six months. To remain in the study for an additional six months, they had to meet set goals for exercise and weight loss. Dr. Kampert, now a sports medicine fellow, says he strongly believes in the need to “invest time in our patients now. That can pay off in the long run for them, the healthcare system, insurance

Dr. Debasis Sahoo, left, and Dr. Matthew Kampert at Cleveland Clinic South Pointe Hospital providers and the community (Photo by Don Gerda taken prior to March 1, 2020.) as a whole.” The study’s one-year goal was for participants to have become Before becoming a physician, Debasis Sahoo, MD, (IM’11, independent exercisers. “They Matthew Kampert, DO (FM’19, PULMCC’14), a pulmonary specialist also know how to eat, when to eat, PC/SM’20), was an exercise on the staff of the Cleveland Clinic how to exercise,” Dr. Kampert says. physiologist. In that role, he says, Respiratory Institute, he established “They know how to pick themselves he saw firsthand how people a research study called THE up when they slip, how to overcome improved their health through BRIDGE PROJECT. The name was obstacles. Behavioral intervention lifestyle choices. He wanted to inspired by Dr. Kampert’s father, in the study gives them the tools help influence the direction of who built bridges, and the prospect healthcare, turning it toward of helping patients lead healthier and cues to recognize when they disease prevention. In December lives by bridging gaps in their access are off track and know how to come 2018, as a family medicine resident to community resources, exercise back to center. After one year, they at Cleveland Clinic South Pointe technology and education. The have changed as people—now, Hospital, he got that chance. name is an acronym for “Targeted they are exercisers.” With the help of a mentor, Healthcare Efforts to Bridge Dr. Sahoo, who helped develop Resources, Improve the Develop- the protocols and obtain internal ment of Guideline-Based Exercise approvals to conduct the study, Prescription and Reduce Obesity which has concluded, says he is Behavioral intervention by Joining Education, Community encouraged by the participants’ progress and impressed by gives them the tools and and Technology.” The research project drew 30 Dr. Kampert’s vision. cues to recognize when participants, all with a BMI over “As physicians, we are only trying to treat the sick,” he says. “If we they are off track. After 30. Their resting metabolic rate also was measured to determine change that goal and work to get one year, they have how many calories they burned people healthy, we are solving a big problem in our society. That’s what changed as people—now, in a 24-hour period, and cardiopulmonary exercise tests fascinated me. We are self-motivat- they are exercisers. determined how much oxygen ing patients. We are not just taking they consumed while exercising care of medical problems but also —Matthew Kampert, DO and how hard their hearts making sure that the community can worked as they did so. get healthier than they are now.” ■

20 ALUMNI CONNECTION – ISSUE 2, 2020 IN THE NEWS Alumnus Models Healthcare for Vogue

Siriorn P. Watcharananan, MD (ID’04, MN’05), has a new position to add to her professional CV: cover model for Vogue Thailand. And like other Vogue models, she is wearing the latest fashion—in this case, a mask and gown. “I couldn’t imagine myself being on the cover dressed as a model,” she says. “The gown and N95 mask I wore is the dress that fits me the most.” Dr. Watcharananan is an infec- tious disease specialist at the Praram 9 hospital in Bangkok and an associate professor in the section of Infectious Disease, Department of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok. She was invited to be on the cover for a story on the COVID-19 pandemic (Magazine photos provided by Dr. Watcharananan.) that includes healthcare providers and others working behind the She says her picture is representa- scenes and on the front lines. tive of all doctors during this global “As an ID doc, I cared for the crisis. “Healthcare workers are I couldn’t imagine COVID-19 cases and helped out everyone’s heroes, and if you see with the infection control plan my picture, I would like to greet you myself being on the during the outbreak,” she says. “My with my best wishes for everyone to cover dressed as a model. colleagues and I worked on a few stay strong, with a good spirit, and collaborative projects with national to be safe during this pandemic.” The gown and N95 mask agencies, including a study of saliva Dr. Watcharananan says that all I wore is the dress that as a way of diagnosing COVID-19 Cleveland Clinic alumni “would like and a dry-heat and UV-sterilization to continue to contribute our best care fits me the most. study to reuse masks. Both projects to society worldwide.” She adds, “It —Siriorn P. Watcharananan, MD had a strong impact as they later has been 15 years since I graduated, became national guidance.” and I miss Cleveland Clinic.” ■

A publication for Cleveland Clinic medical alumni and friends. – clevelandclinic.org/alumni 21 IN THE NEWS Alumni Couple Weds on Cleveland Clinic Rooftop Cleveland Clinic before starting as a Cleveland Clinic staff physician in Pulmonary Medicine in 2018. Since April, she has been on medical intensive care unit service for two weeks and the Advanced Lung Disease Unit for two weeks. Some of her patients have had COVID-19. “As weeks have gone by, we have learned a lot about the disease, developing protocols and best practices,” Dr. Gadre says. “Our patient outcomes have been quite remarkable, as I have been able to see many patients recover.” She says that she and her husband are fortunate to be in Dr. Chaudhury and Dr. Gadre are married the same profession. by the Rev. Brent Raitz (Photos courtesy “We understand each other’s of Caregiver Communications) concerns, hours, affinity for our patients’ well-being and dedication Love knows no bounds. Cleveland Dr. Gadre thought of to our profession,” she says. “The Clinic physician Shruti Gadre, MD Cleveland Clinic. pandemic only underscores this (IM’15, PULMCC’18), and Pulkit “Cleveland Clinic has a special importance. In this time of crisis, Chaudhury, MD (IM’16, VM’17), place in our story. It’s where we my husband and I have been were planning a destination wedding met, and it is our second home,” inspired by how we see the best in Boston on May 16 with 100 Dr. Gadre says. of people and the collective relatives and friends. When gather- On May 16, Dr. Gadre and community. Thank you to everyone ings and events had to be canceled Dr. Chaudhury were married who made our rooftop Cleveland because of the pandemic, the on the Cleveland Clinic rooftop, Clinic wedding possible!” ■ couple wouldn’t let it stop them which overlooks downtown —Article provided by from marrying. Cleveland. The Rev. Brent Raitz, Caregiver Communications a Cleveland Clinic chaplain, officiated, with family and friends attending virtually. The couple met at Cleveland Cleveland Clinic Clinic during their internal has a special place medicine residencies seven years ago. Dr. Chaudhury completed in our story. It’s a vascular medicine fellowship at Cleveland Clinic and moved where we met, to Iowa City for his cardiology fellowship at the University of and it is our Iowa, where he has been for the past three years. In July, he joined second home. Cleveland Clinic’s Cardiology staff. —Shruti Gadre, MD After Dr. Gadre’s internal medicine training, she completed her pulmo- nary/critical care fellowship at

22 ALUMNI CONNECTION – ISSUE 2, 2020 IN THE NEWS

Cleveland Clinic ranked the No. 2 hospital in the United States Our hard work continues to be recognized. Cleveland Clinic was named AlumniConnect is the No. 2 hospital in the United States by the 2020-21 U.S. News & World Report “Best Hospitals” rankings. We also ranked as the No. 1 the fastest and easiest hospital in Ohio and metro areas for Cleveland, Akron and Miami/ way to network from Ft. Lauderdale. Our specialty care remains exceptional. We are ranked nationally in anywhere in the world! 14 specialties, including 13 in the top 10. Cleveland Clinic also received the highest rating in all common conditions and procedures The network combines your Alumni profile rated by U.S. News. and information you’ve shared with us into Our Cleveland Clinic national rankings are: one powerful tool, allowing you to find • Cancer – No. 5 Cleveland Clinic alumni from any • Cardiology & Heart Surgery – No. 1 (for the 26th consecutive year) specialty and location you choose. Take • Diabetes & Endocrinology – No. 6 advantage of a tool that will help you: • Ear, Nose & Throat – No. 16 reconnect with former colleagues, • Gastroenterology & GI Surgery – No. 3 classmates, and co-residents, expand your • Geriatrics – No. 2 business reach and referral base, and so • Gynecology – No. 2 much more. There are over 22,000 • Nephrology – No. 5 alumni. Get started by reviewing your • Neurology & Neurosurgery – No. 9 current profile to make sure all of the • Ophthalmology – No. 10 information is up-to-date. • Orthopedics – No. 9 • Pulmonology & Lung Surgery – No. 4 • Rheumatology – No. 2 • Urology – No. 4 We are high-performing in: • Psychiatry In June, Cleveland Clinic Children’s ranked among the nation’s best pediatric hospitals by U.S. News in its 2020-21 edition of “Best Children’s Hospitals.” The hospital ranked in 10 of 10 specialties surveyed by U.S. News. Visit alumniconnect.ccf.org These rankings are a continued reinforcement of our caregivers’ to claim your profile. Contact us expertise, teamwork and shared sense of purpose for our patients. They at [email protected] or also reflect the legacy of our founders as well as the constituency of 216.444.2487 with questions. physicians and scientists throughout the world who have trained here and their commitment to excellence. We remain grateful for your support of Cleveland Clinic CONNECT throughout the year. OPPORTUNITY Sincerely, NETWORK Tom Mihaljevic, MD UPDATE YOUR INFO CEO and President ALUMNI NEAR YOU

A publication for Cleveland Clinic medical alumni and friends. – clevelandclinic.org/alumni 23 FROM THE ARCHIVES

Rebuilding, and Family Ties

24 ALUMNI CONNECTION – ISSUE 2, 2020 FROM THE ARCHIVES

ALUMNI PERSPECTIVE Leonard Calabrese, DO (IM’78, RH’80) Chair, History Project

Cleveland Clinic’s original building One of the really unusual features that opened in 1921 was beautiful. that I recall was a snack bar in the It had unique features, like an open lobby run by blind volunteers, a and airy space with a skylight, which collaboration between Cleveland gave it more of a feeling of a hotel or Clinic and the Cleveland Sight theater lobby than a hospital setting. Center. I remember going The second and third floors were there as a small child when I wraparound corridors, where a had a doctor’s appointment, physician could take a patient out and it was still a place where the door on one side and walk I could go for lunch when I was around to personally introduce the a medical student. patient to another physician on the As our Archives article notes, other side. It was very intimate. Cleveland Clinic is like a family for However, the story of the original those who work here. And, as the building is forever and inextricably article also states, this is literally linked to the Cleveland Clinic true for those whose children have Disaster of 1929. There was a lot followed in their footsteps. I am of internal debate at the time as to proud to say that my daughter, what to do with the building and Cassandra Calabrese, DO, and whether it should be razed. Dr. Crile I did all of our training at Cleveland thought that they would be able to Clinic and also were both chief reuse it, but it was decided that it residents in medicine—the only should look different. Indeed, it is father-child pair to do so. Today, not recognizable in its present form we work in the same department when compared and collaborate on most of our to its appearance research projects. The article men- on opening day, tions that Robert Eaton LeFevre Feb. 21, 1921. trained at Cleveland Clinic and Some of us feel became a physician here, like his that the structure father, Fay LeFevre. George Crile known as the T and Barney Crile both practiced building is a very at Cleveland Clinic, too. Also, hallowed part of Alexander T. Bunts, Frank Bunts’ the campus, and son, looms large in Cleveland it certainly is an Clinic’s history. Our sense of important part family at Cleveland Clinic, both of Cleveland metaphorical and literal, has Clinic’s story. contributed to our success since Since the our founding in 1921 and our Photos provided by the Cleveland Sight Center. Disaster, this building has under- recovery from the tragedy of 1929. gone varying iterations—patient It is an important aspect of who care, research, administrative offices. we are and who we will become. ■

A publication for Cleveland Clinic medical alumni and friends. – clevelandclinic.org/alumni 25 FROM THE ARCHIVES

1 Building Cleveland Clinic

When the four Founders of Clinic Archives document the woodwork. The first floor housed the Cleveland Clinic—Drs. George Crile, progress of construction, which X-ray department, clinical labs, and Frank Bunts, William Lower, and began in February 1920. Taken pharmacy. The fourth floor was John Phillips—decided to establish monthly, these photos show the home to the art and photography a group practice, their first step was building’s transformation from a department, editorial offices, library, to find a place for it. In October snow-covered foundation to a boardroom, administrative offices, 1919, with the help of lawyer scaffold-covered frame to, finally, a and biophysics lab. On the second Edward Daoust, they organized complete new clinic. The founders and third floors, offices, examining the Association Building Company. held a flag-raising ceremony on rooms, and treatment rooms opened This company raised money by July 3, 1920. Finally, the new onto the waiting room or corridors of selling common and preferred Cleveland Clinic opened on February balconies surrounding the atrium. stock, mostly to the founders, their 21, 1921, marked with a ceremony After the Cleveland Clinic Disaster families, and friends. With funds featuring speeches, music and tours. of 1929, the Executive Committee acquired, the founders signed a The new 41,000-square-foot resolved to remodel the building as 99-year (or “perpetual”) lease for building had four stories, the upper soon as it was proven to be safe. the parcel at the corner of Euclid three centered around a large atrium The Research Department conduct- and East 93rd Street. They hired that functioned as the waiting room. ed extensive tests to ensure that no architects Ellerbe & Co. of St. Paul The exterior was of mottled white poisonous gas remained in the to design the new building. brick, and the rooms inside were building. Cleveland Clinic again Photos now held in the Cleveland finished light gray with birch hired Ellerbe & Co. to design the

26 ALUMNI CONNECTION – ISSUE 2, 2020 FROM THE ARCHIVES

2 3

4 5

1 I Aug 5, 1920: Building, no windows, construction fence, scaffolding from upper to second story window. 2 I March 1, 1920: Snow, piles of wood, construction fence on left side. 3 I May 3, 1920: Scaffolding, pit, people in pit. 4 I June 1, 1920: Back of building—two stories done, scaffolding above. 5 I July 3, 1920: Back of building, scaffolding in center. (Historic pictures of buildings and Dr. LeFevre provided by Cleveland Clinic Archives.)

CLEVELAND CLINIC FAMILIES In the Archives, we often hear staff members observe that Cleveland Clinic “is like a family.” For some remodel. The Board agreed alumni, that’s literally true: Members of the same that converting the building to family, spread across generations and medical administrative offices only would specialties, have shared the Cleveland Clinic experience. best allow it to remain in use The LeFevres are one such family. Fay LeFevre, MD, while protecting any patients followed his father’s footsteps to become a physician. from discomfort associated with At Cleveland Clinic, Dr. LeFevre founded the Depart- Fay LeFevre as a Fellow memories of the disaster. The ment of Peripheral Vascular Disease and led the remodel—and concurrent institution into a new era as the first chair of the newly formed Board construction of a new, larger of Governors. In turn his own son, Robert Eaton LeFevre, also became Clinic building on East. 93rd Street a physician and trained at Cleveland Clinic in surgery and urology. ■ —proceeded throughout 1930. Both buildings opened in 1931. Over the years, the original four-story building has remained part of Cleveland Clinic, housing many different departments and Alumni Connection’s FROM THE ARCHIVES series highlights important or offices. Now known as the T interesting moments in Cleveland Clinic’s history, serving as a retrospective building, it stands as a connection of the institution’s storied past as its 100th anniversary approaches in 2021. to Cleveland Clinic’s heritage and You are invited to submit topics for us to consider. Please contact Mindy legacy of overcoming adversity. ■ Stroh, Senior Director, Alumni Relations, at [email protected].

A publication for Cleveland Clinic medical alumni and friends. – clevelandclinic.org/alumni 27 PHILANTHROPY CENTENNIAL LEGACY SOCIETY

Cleveland Clinic’s founders were visionaries whose in 2021, the Centennial Legacy Society is recognizing tireless commitment to patient care, education and alumni who continue our tradition of excellence by research, and whose willingness to invest their own making a gift of $5,000 or more to an alumni fund that resources in their work, guaranteed Cleveland Clinic’s supports The Power of Every One Centennial Campaign. success and evolution into a leading international We welcome you to join the Society. Your generous gifts healthcare institution. will help better serve patients and enhance the quality of We are thankful for our Centennial Legacy Society training for students, residents and fellows. If you have supporters, who demonstrate this same spirit of any questions about how to become a Centennial Legacy commitment and personal investment, and we hope that Society Member, please contact Mindy Stroh, Senior you will consider joining this dedicated, visionary group. Director, Alumni Relations, 216.444.2487, or at In anticipation of Cleveland Clinic’s 100th anniversary [email protected]. Or, please visit give.ccf.org/alumni. ■

Centennial Legacy Society Members

VISIONARY ($20,000 or more) Dr. Monique P. Kunkel and Dr. Carl W. Groppe, Jr. Dr. B. Warren Pechan and Drs. Syed and Nikhat Ahmed J. Nile Brennecke Dr. Mark and Mrs. Karen Grove Mrs. Paula Pechan Dr. Leonard and Mrs. Marie Calabrese Dr. Pauline C. Kwok Dr. Kuniaki Hayashi Dr. Thomas and Drs. John and Mary Clough Dr. Christopher Leville Dr. Andrew and Mrs. Jane Healy Mrs. Christina Petinga Dr. Robert and Mrs. Pauline Hermann Dr. Andrew and Mrs. Vivien Liu Dr. Kyle Horner Dr. Marc and Mrs. Carol Pohl Dr. and Mrs. Mark Jacobs NeuroSpine Surgical, Dr. Mignucci Dr. Edward P. Horvath Dr. Darin and Mrs. Ruth Powell Dr. Vinod and Mrs. Manju Joshi Dr. Herb Rogove Drs. Octavian and Dr. Louis G. Prevosti Drs. Walter* and Isabella Laude* Dr. Isobel Rutherford Adriana Ioachimescu Dr. Michael Puff Dr. John P. MacLaurin and Dr. Earl K. Shirey Lynn Luthern and Frederic Joyce, MD Dr. and Mrs. Peter J. Reilly Mrs. Sharon MacLaurin Dr. Conrad C. Simpfendorfer and Dr. Leonard and Dr. Barbara Risius Drs. Amy and James Merlino Mrs. Patricia V. Simpfendorfer Mrs. Susan Krajewski Dr. Richard and Dr. Ellen Rosenquist Dr. Max and Mrs. Linda Proffitt Dr. Riaz A. Tarar Dr. Robert and Mrs. Brenda Kunkel Dr. Rochelle Rosian and Dr. Susan Rehm Drs. Jack M. and Lilian T. Thome Dr. Julie A. Lahiri Mr. Jon Straffon Dr. Thomas and Mrs. Janet Rice Dr. S. Raju and Dr. Albert C. Lammert* Dr. Jeffrey* and Mrs. Leah Rudell Dr. Vinod and Dr. Sudarshan Sahgal Mrs. Padmavati Vatsavai Dr. Richard Lang and Dr. Uy and Mrs. Edelisa Santos Dr. Anas Saleh Emily E. Volk, MD, MBA, FCAP and Mrs. Lisa Kraemer Dr. and Mrs. Dennis Schreffler Dr. Kazunari Tanabe Daniel D. Mais, MD Drs. Rande and Linda Lazar, and Dr. Atul Shah Dr. Stephen and Mrs. Gail Young Lauren, Sophie and Charlie/JT Dr. Demin Shen and Dr. Paul M. Shen FOUNDER ($10,000-$19,999) Drs. Chao-wen and D. Anthony Lee Drs. Susan Fox and Dr. Lee and Mrs. Marlene Adler MEMBER ($5,000-$9,999) and Nathaniel D. Lee and Conrad H. Simpfendorfer Dr. Janos Bacsanyi* Drs. Tom and Abby Abelson Kalysta A. Lee Dr. Divya Singh-Behl Dr. Hassan Barazi Dr. Mohamed Atassi Dr. and Mrs. C. Douglas Lees Ms. Sandra S. Stranscak Dr. Kenneth Barngrover Drs. Moises Auron and Marina Duran Dr. Geoffrey and Mrs. Susan Lefferts Dr. Guy Syvertsen and Dr. Conrado and Mrs. Ester Castor Drs. Amiya and Sipra Banerjee Dr. Marc and Mrs. Cynthia Levin Mrs. Patricia Syvertsen Dr. James Chambers Dr. and Mrs. Gordon Bell Dr. James W. Lewis Dr. George Tesar Dr. Ravi Chittajallu Dr. Edwin and Mrs. Beverly Beven Dr. Carl H. Linge Dr. Sanjiv Tewari Dr. Zeyd Ebrahim and Dr. Christine and Mr. Dean Booth Dr. Joseph P. LiPuma and Family Dr. Christopher Y. Thomas Jr Dr. Lilian Gonsalves Ebrahim Dr. Azmy* and Mrs. Ida Boutros Dr. Gilbert and Mrs. Carol Lowenthal Dr. Jin and Mrs. Tammy Wang Dr. Fetnat Fouad-Tarazi Dr. Jennifer Brainard Dr. Thomas and Mrs. Jill Maatman Dr. Bruce and Mrs. Ellyn Wilkoff Dr. Michael and Dr. Haifa Hanna Dr. Johan J. Bredée Dr. Paul and Mrs. Barbara MacGregor Dr. Daniel and Dr. Norman and Dr. Richard P. Carroll Dr. Amy Maneker and Mrs. Donna Marie Wilson Mrs. Maryanne Hertzer Theresa L. Chafel, MD Dr. Brian Herts James B. Young, MD Dr. James Hodgman Dr. Philip Cusumano Drs. George and Lourdes Mathew Dr. Jess Young Dr. Paul C. Janicki and Dr. and Mrs. Ralph DeMatteis Mrs. Shuva and Dr. Atul C. Mehta Drs. Belinda Yen-Lieberman and Dr. Christine A. Quinn Dr. Raed Dweik Dr. H. David Millit James M. Lieberman Drs. Justin and Erin Juliano Dr. Gary H. Dworkin Dr. Tony and Laura Milo Mrs. Kelsey and Drs. Toribio and Susan Flores Dr. Asma M. Moheet & Family Note: An asterisk (*) indicates that Dr. Jonathan Kaplan Mr. Dale and Mrs. Diane Goodrich Dr. Eric and Mrs. Letty Muñoz the Centennial Legacy Society member Dr. William and Mrs. Eugenia Kiser Dr. Raghav Govindarajan Mrs. Paula Ockner has died.

28 ALUMNI CONNECTION – ISSUE 2, 2020 PHILANTHROPY The CARES Act Inspires Charitable Giving On March 27, the Coronavirus Aid, and thereby reduce taxable income. attractive for individuals who would Relief, and Economic Security (CARES) If you have made a cash gift this like to make a significant charitable Act was passed by Congress and year, it counts toward the $300 cap. gift directly from an IRA to a charity signed into law by President Donald Note: A gift to a donor advised fund through a qualified charitable Trump. The $2 trillion economic does not qualify for this new deduction. contribution, while also avoiding stimulus package is designed to Increased Charitable Deduction taxable income. provide immediate relief for individuals Limits: Individuals who itemize can Reminder: Directing a qualified and businesses, including nonprofits. deduct much greater amounts of their charitable contribution to charity The CARES Act was enacted cash contributions this year. Individ- this year (up to $100,000 per in response to the COVID-19 uals can elect to deduct donations up individual, age 70 ½ or older) global pandemic. to 100% of their 2020 AGI (up from will still reduce the taxable IRA As we find ourselves in unprece- 60% previously). The new deduction balance. This allows all taxpayers— dented times, it may be helpful to is for cash gifts that go to a public itemizers and non-itemizers alike— recall that we survived other periods charity, such as Cleveland Clinic. to direct gifts from their IRA to of financial disaster and great Example: An individual who has charities in a tax-efficient manner. economic uncertainty. We may an AGI of $80,000 and makes a The inclusion of an expanded remember the pain of those times, cash gift of $80,000 will have no charitable giving incentive is a critical but what is common to them all is federal income tax liability for 2020. acknowledgement by Congress that the predilection for a rebounding Note these exceptions: the work of nonprofits such as economy. Every “down” era has • The higher deduction does not Cleveland Clinic is essential and been followed by a recovery that apply to direct contributions to a that those who support it will help eventually eclipsed the damage donor advised fund, supporting rebuild the economy and ensure sustained in the prior period. organization or a private foundation. better days ahead for our country. The CARES Act is one way forward • These new limits do not apply to For more information, please to enable this recovery. This package gifts of appreciated stock. contact Mindy Stroh, Senior Director, includes several new charitable Required Minimum Distributions Alumni Relations, 216.444.2487. provisions, as set forth below. Waived in 2020 for Most People: In addition, the Gift Planning team New Above-the-Line Standard Required minimum distributions for at Cleveland Clinic can answer any Deduction Available: Up to $300 individuals over age 72 that would questions you may have about the per tax return in annual charitable have had to start in 2020 do not CARES Act, assist you with a gift to contributions. This is available only have to start until 2021, including Cleveland Clinic’s Covid-19 efforts, to those who take the standard those from defined benefit pension or address other healthcare initiatives. deduction. It is an “above-the-line” plans and 457 plans. While it has You can reach the Gift Planning adjustment to income that will reduce been waived for 2020, the required team at 216.444.1245 or a donor’s adjusted gross income (AGI), minimum distribution remains [email protected]. ■

LEAVE A LEGACY Like many of your peers who trained at Cleveland Clinic, you Sample Bequest Language: “I give and bequeath to may want to support the education of future generations of The Cleveland Clinic Foundation, Cleveland, Ohio, physicians and caregivers. A gift in your will or trust can help (the sum of $______or ______%) to support you meet this goal while allowing you to retain control of your ______.” assets during your lifetime.

FOR MORE INFORMATION ON MAKING A BEQUEST: Contact Mindy Stroh, Senior Director, Alumni Relations, at 216.444.6534, or [email protected].

A publication for Cleveland Clinic medical alumni and friends. – clevelandclinic.org/alumni 29 CONTACTS Contacts

Jay Alberts, PhD Charis Eng, MD, Stanley Hazen, (Staff’05), PhD (Staff’05) MD, PhD Biomedical and her team, in a (Staff’97) and Engineering, was new study published his team have invited to serve on in JAMA Network identified a new the Musculoskeletal Open, identified diet-associated Rehabilitation for the first time gut microbe Sciences Study Section of the National why patients with identical PTEN (phenylacetylglutamine) linked Institutes of Health to review grant mutations often have vastly with cardiovascular disease applications regarding rehabilitation different clinical presentations. and related events, including for impaired physical functioning. They discovered that, in individuals myocardial infarction, stroke with PTEN mutations, copy number and death. Their study analyzed Wilma Bergfeld, variations in the altered gene may samples from more than 5,000 MD (D’68), has modify whether patients develop patients and was published in been elected to be autism spectrum disorder (ASD) the prestigious journal Cell. the 2020–21 Chair and/or developmental delay of the American versus PTEN-related cancer. Michael Kattan, Academy of PhD, MBA Dermatology Serpil Erzurum, (Staff’04), Nominating Committee. MD (Staff’93), Quantitative received a four- Health Sciences, Adarsh Bhimraj, year, $3 million led a group of MD (Staff’09), competitive renewal investigators in the Infectious Disease, for her R01, titled Department of Quantitative Health is the lead author “Nitric Oxide in Sciences in creating a real-time of the Infectious Pulmonary Hypertension.” This dashboard to track COVID-19 case Disease Society grant has been funded for 21 and mortality data in the U.S. of America’s new consecutive years. He worked with Lara Jehi, MD, guidelines for management and in collaborating with colleagues treatment of COVID patients. Tommaso Falcone, across Cleveland Clinic to create a MD (Staff’95), COVID-19 risk prediction calculator. Mina Chung, MD received an Dr. Jehi is Cleveland Clinic’s Chief (Staff’93), is honorary fellowship Research Information Officer; Dr. leading the data from the Royal Kattan holds the Dr. Keyhan and coordinating center College of Obstetrics Dr. Jafar Mobasseri Endowed Chair of a $1.2 million, & Gynecology in for Innovations in Cancer Research. multi-institution the United Kingdom. By comparing a control group of award from the patients who tested negative with American Heart Association. Bradley C. Gill, those who tested positive, the For the “COVID-19 and Its MD, MS (CCL- researchers are determining risk and Cardiovascular Impact Rapid CM’12, U’18) protective factors associated with Response Grant,” the Cleveland has been the virus. In addition, a bibliometric Clinic team will collect data from selected as analysis published in the International 12 intuitions across the U.S. Medical Education Journal of Surgery lists Dr. Kattan Fellow for the as the most highly cited author in 2020–21 academic year. the world in the field of urological

30 ALUMNI CONNECTION – ISSUE 2, 2020 CONTACTS

surgery. He is a pioneer in medical research and the great supportive first clinical trial validation of the risk prediction, and this ranking and mentorship environment in relationship between HSD3B1 highlights the great influence our lung transplant program status and clinical outcomes, his research has had in science and Pulmonary Department.” suggests that genetic testing for and medicine. the presence of HSD3B1(1245C) Laura Nagy, PhD may help physicians identify Eric Klein, MD (Staff’06), in those patients most likely to (U’86), and January delivered benefit from additional and more Margot Damaser, the 24th Annual aggressive treatment. PhD (Staff’05), Mark Keller were honored with Honorary Lecture Andrea Sikon, MD 2020 Urology at the National (Staff’01), is the Care Foundation Institute on Alcohol Abuse and 2020 recipient Awards. Dr. Klein Alcoholism, part of the National of the Society for received the Institutes of Health. This lecture General Internal Richard D. series features a lecture by an Medicine’s Williams, MD outstanding alcohol researcher Association of Chiefs Prostate Cancer whose work makes significant and Leaders of General Internal Research Excel- and long-term contributions to Medicine Recognition Award. This lence Award, our understanding of how alcohol award is given annually to the general and Dr. Damaser received the affects the body and mind. internal medicine division chief Distinguished Mentor Award. who most represents excellence in Jesse Schold, division leadership. “This is a highly Prakash Kotagal, PhD, (Staff’09), competitive award,” says Abby MD (CHN’86, received a Spencer, MD, MS (Staff’14), NPHY’88), re- one-year, Director of the Internal Medicine ceived the 2020 $198,000 grant Residency Program. “Dr. Sikon Lifetime Achieve- from the National stood out as having strengthened ment Award from Science Foundation our GIM division with special the Association of titled “Epidemiology of COVID-19 attention to growth in all areas, Indian Neurologists in America. Based on Surveillance of Deceased with a strong focus on faculty Donors in the United States.” development and mentoring.” Carli Lehr, MD (PULMCC’18), Nima Sharifi, MD Gary Silver, MD (S’70, TCS’73) is the holder of (Staff’13) and his started a heart surgery program the newly estab- team, in a new in San Jose, California, after lished Gregory clinical study six years at Cleveland Clinic, three and Maureen published in JAMA of which were with Donald Effler, Church Term Chair Oncology, show MD. “After a couple of years, we in Lung Transplantation Research. that the genetic were getting very busy,” Dr. Silver “This is a great honor, especially variant HSD3B1(1245C) is says. “I was asked to join Rotary, at this early stage in her career,” associated with faster progression and that is when I started our Adult says Raed Dweik, MD, MBA, to treatment resistance and shorter Gift of Life project. Our first case Respiratory Institute Chair. “It is overall survival in metastatic was in 1986. The program brought a reflection of her outstanding prostate cancer. This study, the Continued on page 32

A publication for Cleveland Clinic medical alumni and friends. – clevelandclinic.org/alumni 31 CONTACTS Contacts

Continued from page 31 Abby Spencer, MD, Robert Wirka, MD patients in need of open heart MS (Staff’14), (CCLCM’10) surgery from around the world has been accepted received the 2019 who were too poor to get treated as a Fellow in Irvine H. Page in their home country.... mostly the 2020-2021 Junior Faculty in need of single or double valve Hedwig van Research Award replacement. EVERYTHING was Ameringen for his contributions free to them, and I and my team Executive Leadership in Academic to cardiovascular research. The award, donated the surgery, as did the Medicine (ELAM) Program for which recognizes investigators hospital. Rotary provided taking Women. The ELAM program is early in their faculty careers for care of the one family member a one-year, part-time fellowship demonstrating leadership potential who came with the patient. We that offers leadership training, in cardiovascular research, is did 46 patients from over 30 coaching, networking and sponsored by the American different countries. It was mentoring for women who hold Heart Association Council on a very rewarding project.” leadership positions in academic Arteriosclerosis, Thrombosis and medicine, dentistry, public health Vascular Biology. As an award Mark S. Soberman, and pharmacy. Dr. Spencer also recipient, Dr. Wirka was invited MD, MBA, FACS was awarded the Accreditation to share his work at the Lerner (TS'93), after Council for Graduate Medical Research Institute’s 36th Annual 20 years as an Education’s 2020 Parker J. Page Lecture, which honors Irvine academic general Palmer Courage to Teach Award Page, MD, a world-renowned thoracic surgeon and was the keynote speaker Cleveland Clinic physician who and seven years at Weill Cornell Medicine’s 3rd played a major role in founding the as a healthcare administrator, now Annual Primary Care & Hospital American Heart Association, and all serves as the Senior Safety Officer Medicine Innovations Symposium. pioneers in heart research and care. for Ethicon, the surgical device Dr. Wirka presented “From GWAS division of Johnson & Johnson. Suthep Udom- to Mechanism in Coronary Artery “The safety organization at J & J sawaengsup, MD, Disease.” Joe Loscalzo, MD, PhD, is part of the Office of the Chief FRCST, FACS MA, head of the Department of Medical Officer, reporting (AL/FSE'07) is Medicine at Brigham and Women’s independently of the company’s Director of the Hospital, was the Page lecturer. commercial arm,” he says. Bariatric and “Overseeing medical safety for Metabolic Institute While attending the Lerner College the global surgery group, my and an associate professor in the of Medicine, Dr. Wirka conducted responsibilities include Department of Surgery, Faculty his thesis research in the lab of collaborating with colleagues of Medicine, at Chulalongkorn Jonathan Smith, PhD, Professor in new product development, University in Bangkok, Thailand. of Molecular Medicine, where he research and development, He also is President of the published a first-author paper on global strategy and marketing Endoscopic and Laparoscopic atrial fibrillation genomics. After and post-market surveillance, Surgeons of Asia and President graduating, he completed his mergers and acquisitions to ensure of the Laparoscopic Endoscopic internal medicine residency at the safest design, manufacture Surgeons of Thailand. the University of California, San and use of the Ethicon portfolio Francisco, and a cardiology of medical devices.” fellowship at Stanford University. He recently published a high-impact

32 ALUMNI CONNECTION – ISSUE 2, 2020 CONTACTS

paper in Nature Medicine on the cell phenotypes in atherosclerosis using single-cell RNA sequencing.

“It is so very wonderful to see one of our CCLCM alumni win the AHA Junior Page Award,” says Serpil Erzurum, MD, Chair of the Lerner Research Institute and Professor of Medicine. “Dr. Page would have been so proud!”

Elham Yousef, MD, MBA (Staff’13), Hospital Medicine, received the Dean’s Academic Achievement Award Photos above and below taken prior to March 1, 2020. for outstanding Joseph “Joe” Couri, MD (IM’79, RH’81), retired rheumatologist and academic record at Case Western songwriter, and hip-hop recording artist Warith Muhammad, wrote a song Reserve University’s Weatherhead and made a music video together called “Don’t Start,” featuring singer/ School of Management. She also songwriter Maria Criss. They live in Peoria, Illinois, where Don't Start is a received membership to Beta program in association with Carl Cannon and his Elite Program designed Gamma Sigma, the International to prevent children and teenagers, especially those at risk, from joining Honor Society for Collegiate Schools gangs and becoming involved with drugs, bullying and gun violence. of Business in recognition of high Dr. Couri and Warith Muhammad met through Mirror Image Studios in scholastic achievement. Bartonville, Illinois, where they both have recorded.

“We submitted the PHYSICIAN song to an international competition through JOB OPENINGS The Akademia Music Enjoyed your training at Awards program in Cleveland Clinic? Why Los Angeles, and it was not return to continue named song and video your career? of the month in the hip/ hop genre in 2017,” Visit jobs.clevelandclinic.org Dr. Couri says. “War and search under physicians was given artist of the year for 2017 for his work, including ‘Don't Start.’ in the professional areas, This year, we were given the Akademia Music Executive award, their to view available positions highest award. We were very honored to receive it. ‘Don't Start’ is being and find your next amazing played on internet radio on multiple stations around the world.” Their opportunity. video will be distributed to Peoria-area schools. “Ideally, we would like to spread our message around the country,” Dr. Couri says. ■

A publication for Cleveland Clinic medical alumni and friends. – clevelandclinic.org/alumni 33 CONTACTS Contacts

Visit to Marshfield Clinic Susan Rehm, MD, ran into several Cleveland Clinic alumni at Marshfield Clinic in Marshfield, Wisconsin, where she gave a grand rounds presentation on “Professional Fulfillment.” “It was so great to reconnect and learn from one another,” she says. One alumnus whom she saw, Alpa Shah, MD, (P’98), Chair, Marshfield Clinic Board of Directors, is the first woman elected to her position in the 103-year history of the organization. She also is Chair, Physician and Allied Professionals Health Committee, leading institutional initiatives for From left: Alpa Shah, MD (P’98); Richard (Dick) Dart, MD (IM’71); Rana Nasser, MD physician and allied professionals’ (IM’94, ID’96), Susan Rehm, MD. Not pictured: Miland Shah, MD (IM’95, CARD’98), health and wellbeing. ■ invasive cardiology at Marshfield Clinic.(Photo taken prior to March 1, 2020.)

AUTHOR’S CORNER

Gregory L. Hall, MD (IM’94), has published a The book is available book, Patient-Centered Clinical Care for African from Springer publish- Americans: A Concise, Evidence-Based Guide to ing, Amazon, and Important Differences and Better Outcomes. other national outlets. The book is especially timely “with poor chronic Dr. Hall is Co-Director disease outcomes in African Americans at the of the Northeast Ohio forefront of national news due to the COVID-19 Medical University pandemic, and a new crop of residents,” he says. (NEOMED)-Cleveland It would be good preparation “for the increased State University number of African Americans they will see at Partnership for Urban Health and Director for African hospitals this summer and thereafter. As I remember American Health, Research, Education & Policy at from my days at Cleveland Clinic, many of these Cleveland State University, as well as associate residents have had minimal contact with African professor of Internal Medicine and Integrative Americans prior to their arrival in July.” Medical Sciences at NEOMED. ■

34 ALUMNI CONNECTION – ISSUE 2, 2020 CONTACTS

Dr. Hong Honored by Crain’s as a Woman of Note Sandra Hong, MD (Staff’05), of “Today,” the article says, “she Cleveland Clinic’s Department of leads a multidisciplinary team of Allergy and Clinical Immunology, allergists, pediatric psychologists was named by Crain’s Cleveland and dieticians working to diagnose Business publication as one of its allergies and disease caused by “Women of Note.” The annual list reactions to food.” honors inspiring women whose The article notes that about dedication and achievements enrich 32 million people in the U.S. have Northeast Ohio. Nominated by a food allergies, including 8% of panel of Crain’s editors, honorees children, and that Dr. Hong’s are selected from a wide pool of own nephews have severe peanut women who serve in a variety of allergies, “the most common cause leadership roles. of food-induced anaphylaxis.” Dr. Hong is Regional Medical The new center, based in Dr. Director of Cleveland Clinic’s Hong’s native Strongsville, also Dr. Hong told the magazine that southern region, which includes treats patients with diseases her Korean-born mother and father, Brunswick, Medina, Wadsworth, including asthma and eczema. a former cytologist and grocery-store Olmsted Township and Strongsville. Calling FACE “a labor of love,” she owner, instilled in her “the values of She helped develop northern Ohio’s also said that “researching and hard work and kindness” and that first food-allergy center, the Food eventually improving every facet of she is “blessed to be doing a job Allergy Center of Excellence (FACE), an individual’s life” is what sparked that speaks to me and allows me which launched in February. her interest in the field. to help others.” ■

Dr. Joseph Howarth Celebrates His 100th Birthday Joseph Howarth, MD (NS’51), at what was then Orange Memorial celebrated his 100th birthday on Hospital. He was there for nearly July 9. 25 years, becoming Chief of Staff A native of England, Dr. Howarth in 1966. graduated from the medical school In 1975, Dr. Howarth joined the of the University of Manchester. United States Air Force. When he During World War II, he served in left the Air Force, with the rank of the British Royal Army Medical colonel, he moved to Santa Barbara, Corps, and after the war, he California, and became Director of emigrated to North America. He the Neck and Back Clinic of Samsun completed his neurosurgery training Medical Clinic. at Cleveland Clinic under W. James Dr. Howarth retired in Palm Gardner, MD. After serving on Desert, California, with his wife of Cleveland Clinic’s neurosurgery staff, 58 years, Peggy. He now enjoys Dr. Howarth moved to Orlando, traveling and visiting his six children Florida, and entered private practice and five grandchildren. ■

A publication for Cleveland Clinic medical alumni and friends. – clevelandclinic.org/alumni 35 IN MEMORIAM In Memoriam

Judith Mary great-great granddaughter, as well Dr. Naguib was a successful Darmady, MD as many nieces, nephews and academic physician. “This is a (PD’65), great-nieces and nephews. terrible loss to our GENA family, passed away to the Anesthesiology Institute, on April 13 Ernest William to the Cleveland Clinic and to the at Basingstoke Thomas whole anesthesia community,” says and North McCrank, MD Maged Argalious, MD, MSc, MBA, Hampshire (IM’66), age Professor and Chair, Department Hospital, in 79, died Dec. of General Anesthesiology. “To Basingstoke, Hampshire, England, 10 in Calgary, us, he was a colleague, a friend, after contracting coronavirus. An Alberta. He and a mentor.” esteemed physician, renowned for was born on her work in Basingstoke, she was April 4, 1940 Satoru awarded an OBE in the Queen’s in Val-d’Or, QC. He and his wife, Nakamoto, MD birthday honors list in 2010. She Jan, were married 55 years. They (CARD’57), chaired two charities, the Ungureni enjoyed golfing, tennis, hiking, 92, one of Trust in Romania and United Aid biking, skiing and traveling. He is Cleveland for Azerbaijan. Dr. Darmady had survived by his children, Colleen Clinic’s oldest a long and distinguished career (Jeff Nazarchuk) of Calgary, and and most as a pediatrician at Basingstoke Ernest of Cultus Lake, British distinguished Hospital before retiring in 1995. Columbia, a brother, Neil (Sue) of staff members, She was remembered by friends Calgary, a granddaughter and other passed away peacefully at home and colleagues as kind and loving family members. Dr. McCrank May 5 after a brief struggle with generous, “commanding the earned his medical degree in 1964 cancer. He joined Cleveland Clinic respect, love and friendship of from Queen’s University and went in 1956, and in 1967, he was most people in Basingstoke and on to a residency in psychiatry, work appointed head of the newly formed Deane,” and as “a consummate at Homewood in Guelph, Ontario, Department of Hemodialysis, where professional” who “discharged her and then to Western University in he became a pioneer in dialysis and duties with great passion and London, Ontario, where he became renal transplantation. He directed gained the respect of one and all.” Emeritus Professor in Psychiatry. He the kidney transplantation program specialized in anxiety disorders and in its crucial, formative years. His Andrew served on the Mental Health Review colleagues admired Dr. Nakamoto’s Donnelly, MD Board of Alberta. intellect, perseverance and innova- (U’59), died tions that produced the seminal March 15 Mohamed work in renal transplantation. He following a brief Naguib, MD was considered the consummate illness. He had (Staff’10), a physician, researcher and educator, a distinguished staff member who made patient care his priority. career as a of Cleveland Dr. Nakamoto is survived by his urologist for Clinic’s Anes- wife of 62 years, Grace Nakamoto over 30 years. He is survived by thesiology (nee Maruo); children Dean four children, Margaret (Denis Institute, died Nakamoto, MD (Miki), Donna Cormier), Eilish, Kelly and Michael, at his home in Lew (Christopher, MD) and David and his brother Desmond (Moyra) mid-February. Renowned nationally Nakamoto; grandchildren Kent and Donnelly, as well as three grandchil- and internationally for his contribu- Alissa Nakamoto, and Alexander, dren, two great-grandsons and one tions to the field of anesthesiology, Maria and Michele Lew. (Please

36 ALUMNI CONNECTION – ISSUE 2, 2020 IN MEMORIAM

see related story, page 39) Reed; and numerous in-laws, Euclid, Ohio, and the grandfather of Please consider a contribution in nieces, nephews and cousins. His seven and great-grandfather of nine. memory of Dr. Satoru Nakamoto to parents and brother, H. Thomas Cleveland Clinic Glickman Urological Norris, MD, preceded him in death. Robin Eric & Kidney Institute—Hypertension & Rosenberg, Nephrology Education. Gifts can be William MD (S’82, sent to Cleveland Clinic Foundation, Proudfit, MD CRS’83), died P.O. Box 931517, Cleveland, OH (IM’43), died in February. 44193-1655. Feb. 11, just He graduated five days shy from Trinity Donald of his 106th College Geoffrey “Don” birthday. He with honors Norris, MD was the loving in biology and AOA from Temple (PD’92), 79, husband of University School of Medicine. He died at home Thelma J. (nee Janaske). Born in received his medical degree from with family in Connellsville, Pennsylvania, he the Lewis Katz School of Medicine Audubon, PA was a graduate of Washington at Temple University and went on on April 26, and Jefferson College, 1935, and to complete his residency and from cancer. Harvard Medical School, 1939. fellowship at Cleveland Clinic in A dedicated pediatric hematologist/ After interning at Geisinger 1983. He was board certified in oncologist, he held positions at Memorial Hospital in Danville, colon and rectal surgery and general Cleveland Clinic, the Children’s Pennsylvania, he trained in surgery. He practiced in the greater Hospital of Philadelphia, and the internal medicine and cardiology Philadelphia area, where he was University of Medicine and Dentistry at Cleveland Clinic from 1940 to named a top doctor by Philadelphia of New Jersey, before launching a 1943, and then served in the U.S. Magazine. He was a member of the second career in peer review and Army Airforce from 1943 to 1946. Undine Barge Club and regularly quality improvement in the field of He returned to Cleveland Clinic in rowed his single scull on the medicine. He was born on June 19, 1946 as a staff member in the Schuylkill River. Dr. Rosenberg is 1940, to Herbert Thomas and Ruth Department of Cardiopulmonary survived by his wife, Irene, and Maude (Church) Norris of Pullman, Disease and soon became head of his son, Christopher. WA. He earned his medical degree the section of Electrocardiography. from the University of Pennsylvania Years later, he became the head Merton School of Medicine, and pursued of the Department of Clinical Seigleman, MD advanced medical training at Henry Cardiology. An author and coauthor (AN’61), died Ford Hospital in Detroit, Michigan, of many papers or book chapters, he Feb. 25 at the and the Mayo Graduate School of served a term on Cleveland Clinic’s age of 96. He Medicine. While stationed in Frankfurt, Board of Governors and received was on the staff Germany, he served three years as a the Distinguished Fellows Award of of Cleveland general medical officer in the Third Cleveland Clinic's Alumni Association. Clinic’s Armored Division of the U.S. Army, He retired in 1979 but continued Department reaching the rank of major. He is researching and writing for many of Anesthesia from January 1960 survived by Sue, his wife of 37 years. He was the father of John P. to March 1961. He always spoke years; their son Geoffrey; his former Proudfit (Donna) of North Ridgeville, highly of his time at Cleveland Clinic wife, Bonnie Hepburn, MD; their Ohio; Ann P. Iannarelli (Dennis J., and stayed in touch with many daughters Wendy (Stuart) and Robin deceased) of Cleveland Heights, (Peter); granddaughters Casey and Ohio; James H. Proudfit (Karen) of Continued on page 38

A publication for Cleveland Clinic medical alumni and friends. – clevelandclinic.org/alumni 37 IN MEMORIAM In Memoriam

Continued from page 37 of Cardiovascular Medicine, a role Professor of Medicine in the Division colleagues. He became a Consultant he served in for 19 years. He was of Cardiology at the University of in Anaesthetics at Blackburn Royal also the Director of the Heart Failure Utah Medical Center, receiving five Infirmary in East Lancashire, and Transplantation Fellowship. Outstanding Teaching Awards during England, established a Pain Relief He served on the editorial board his tenure there. Clinic and was the founder of the for many leading specialty journals “It is with tremendous sadness East Lancashire Hospice, which he and led numerous studies related that we mourn the passing of our oversaw from its inception Feb. 25, to cardiac transplantation and dear colleague and friend, David 1981, through fundraising, to the treatment of congestive heart failure. Taylor,” says Lars Svensson, MD, opening of a 10-bed facility on He was once named as one of the PhD, Chair of the Sydell and Arnold June 21, 1984. He worked there top 27 cardiologists in the United Miller Family Heart, Vascular & tirelessly for many years. He was States by Forbes Magazine. Thoracic Institute. “He was an awarded an OBE in 1985 and the Dr. Taylor’s contributions to heart outstanding physician and a Anne Norfolk Lifetime Achievement transplantation were recognized strong leader. He was highly Award by Hospice UK in 2014. globally. He was President of the respected by colleagues and International Society for Heart well loved by his patients.” David O. Taylor, and Lung Transplantation in “From his first days at Cleveland MD (Staff’01), 2012-13, and his contributions Clinic, Dr. Taylor’s clinical impact Professor of to the International Transplant and profound professional abilities Medicine, died Registry and Guidelines significantly were immediately evident,” says Feb. 5. He was improved the care of multiple Randall C. Starling MD, MPH. “He 60 years old. generations of patients. has left a legacy on our trainees and In 2001, Dr. Prior to joining Cleveland Clinic, his colleagues that will impact the Taylor joined Dr. Taylor served 10 years at the care of patients around the world.” Cleveland Clinic University of Utah where he was He is survived by his wife, Linda, as a staff physician in the Robert Medical Director of the Cardiac and children, Matthew, Alyssa and Suzanne Tomsich Department Transplant Program. He was a and Mackenzie.

MEMORIAL GIVING Giving to medical education at Cleveland Clinic in memory of a fellow alum is a meaningful way to express sympathy. Please be assured that your gift will help preserve the highest standards of education and training of future generations of physicians and scientists. For more information, please call Mindy Stroh, Senior Director, Alumni Relations, at 216.444.2487.

38 ALUMNI CONNECTION – ISSUE 2, 2020 IN MEMORIAM

Kidney Transplant Pioneer Satoru Nakamoto, MD, Dies at 92

Satoru transplantation could offer patients formed Department of Hemodialysis. Nakamoto, a better quality of life in the long He retired in 1991. MD run than chronic hemodialysis. By 2013, the year that (CARD’57), With some trepidation, Dr. Cleveland Clinic celebrated its renowned Nakamoto suggested to Dr. Kolff 50th anniversary of kidney trans- for his that he organize a kidney transplant plantation, over 3,000 kidney foundational program at Cleveland Clinic. He transplants had been performed. work in the thought his idea might be rejected More than 75 patients had lived field of kidney because of Dr. Kolff’s focus on with the same functioning kidney dialysis and dialysis, but to his surprise, Dr. transplant for 30 to 45 years. renal transplantation, passed away Kolff not only called it “an excellent Even with all of his professional peacefully at home on May 5, at idea,” but also put Dr. Nakamoto accomplishments and acclaim the age of 92. (Please see obituary, in charge of the program. throughout his long and distin- page 36) According to an early history guished career, Dr. Nakamoto’s Born in Yamaguchi prefecture, of kidney transplantation at reputation remained that of a Japan, he earned his medical degree Cleveland Clinic written by Dr. humble, modest man, and a at Yamaguchi Medical College after Nakamoto, the first one performed loving husband and father. World War II and emigrated to the there was before he started the “Throughout everything, my United States in 1953 as a medical program, on Oct. 25, 1957, from dad was still a family man,” says intern. In July 1956, he joined a deceased donor to a 23-year-old older son Dean Nakamoto, MD. Cleveland Clinic as a research fellow man. On Nov. 27, 1962, the “He traveled and worked late a for Willem Kolff, MD, famed for his newly established Cleveland Clinic lot, but he always made time for work in kidney dialysis. Recalling Transplantation Committee had family vacations. We did a lot of his arrival there, Dr. Nakamoto its first meeting, with members fishing together on our yearly trips wrote, “As a Japanese exchange Dr. Nakamoto, Dr. Kolff, Dr Gene to Canada, and we played a lot of fellow, I was excited but scared to Poutasse, Dr. Ralph Straffon golf together—though we were be working with such a prominent and Dr. Donald Senhauser. On not good golfers.” researcher.” He soon became a Jan. 9, 1963, Cleveland Clinic’s He didn’t realize while growing valued member of Dr. Kolff’s team. second-ever kidney transplant was up just how famous his father was, In April, 1961, Dr Nakamoto, by performed, from a deceased donor he says. “I really had no idea. He then a staff member, attended the to a 48-year-old woman. The first didn’t talk too much about his work. annual meeting of the American living related kidney transplant It was my sixth-grade science Society of Artificial Internal Organs, took place April 1, 1963, from a teacher who told me.” where he learned that teams at the 40-year old mother to her 14-year After retiring, Dr. Nakamoto Peter Bent Brigham Hospital in old daughter. enjoyed spending time with his Boston and Hopital Necker in Paris In 1967, when Dr. Kolff moved wife, Grace, their children Donna had performed successful kidney to the University of Utah in Salt Lew, Dean and David and their transplants in a small number of Lake City to develop a wide range grandchildren, keeping up with patients beginning in 1954. He of artificial organs, Dr. Nakamoto friends from around the world, realized that successful kidney succeeded him as head of the newly gardening and golfing. ■

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