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Gene % HDV Positive Cells % Infection Compared to Sictrl P-Value FDR

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Gene % HDV Positive Cells % Infection Compared to Sictrl P-Value FDR % HDV % infection Gene positive compared to p-value FDR Toxicity cells siCtrl A2M 9,45 63,81 0,0001 0,0002 0,11 A4GALT 17,61 118,94 0,0887 0,1607 -0,13 A4GNT 16,11 108,83 0,0939 0,1683 0,20 AACS 15,76 106,48 0,5123 0,5979 0,00 AADAC 14,41 97,34 0,5533 0,6323 -0,03 AADACL1 14,44 97,53 0,2998 0,3678 0,14 AADAT 13,36 90,26 0,1557 0,2308 0,17 AAK1 18,00 121,58 0,0007 0,0028 0,04 AANAT 12,21 82,46 0,0004 0,0012 0,09 AARS 17,17 115,94 0,0671 0,1111 -0,13 AARSD1 14,78 99,83 0,8307 0,8622 -0,09 AASDH 18,69 126,24 0,0054 0,0129 -0,04 AASDHPPT 16,84 113,73 0,2685 0,3738 -0,05 AASS 16,33 110,31 0,0531 0,0836 -0,05 AATF 18,57 125,42 0,0111 0,0254 0,07 AATK 14,80 99,98 0,6699 0,7166 0,18 ABAT 16,31 110,16 0,0725 0,1215 0,34 ABCA1 14,86 100,36 0,9669 0,9774 0,18 ABCA10 13,09 88,44 0,3205 0,4130 0,09 ABCA12 17,44 117,81 < 0.0001 < 0.0001 -0,03 ABCA13 14,77 99,76 0,9409 0,9609 -0,04 ABCA2 10,93 73,82 0,0001 0,0003 0,19 ABCA3 10,03 67,74 0,0913 0,1645 0,23 ABCA4 12,89 87,10 0,2968 0,3890 -0,08 ABCA5 17,00 114,80 0,0598 0,1252 0,04 ABCA6 15,58 105,20 0,2367 0,3178 0,13 ABCA7 11,40 77,03 < 0.0001 < 0.0001 0,35 ABCA8 15,88 107,30 0,0001 0,0005 0,06 ABCA9 11,86 80,11 < 0.0001 < 0.0001 0,29 ABCB1 12,79 86,41 0,2516 0,3539 0,09 ABCB10 13,81 93,28 0,4109 0,4855 0,12 ABCB11 19,08 128,88 0,0079 0,0194 0,00 ABCB4 14,67 99,12 0,9630 0,9736 0,10 ABCB5 15,34 103,59 0,4524 0,5677 -0,02 ABCB6 11,31 76,40 < 0.0001 < 0.0001 0,19 ABCB7 10,89 73,56 0,0285 0,0575 0,04 ABCB8 13,69 92,50 0,0355 0,0652 0,16 ABCB9 14,27 96,37 0,8926 0,9239 0,05 ABCC1 15,92 107,56 0,2517 0,3138 0,03 ABCC10 16,25 109,78 0,0002 0,0007 -0,01 ABCC11 13,75 92,89 0,0762 0,1259 0,02 ABCC12 13,36 90,26 0,4284 0,5206 0,04 ABCC2 15,44 104,26 0,5549 0,6088 0,18 ABCC3 8,28 55,92 0,0071 0,0217 0,35 ABCC4 16,78 113,33 0,2345 0,3063 -0,13 ABCC5 12,41 83,84 0,1472 0,2225 -0,09 ABCC6 13,71 92,61 0,2663 0,3526 0,27 ABCC8 14,50 97,94 0,7328 0,7731 0,13 ABCC9 9,71 65,61 0,0065 0,0134 0,30 ABCD1 10,21 68,93 0,0834 0,1357 0,19 ABCD2 14,87 100,43 0,7294 0,7910 -0,27 ABCD3 14,42 97,39 0,7064 0,7684 -0,08 ABCD4 14,35 96,96 0,1824 0,2529 0,01 ABCE1 10,82 73,07 0,1231 0,2028 0,13 ABCF1 20,38 137,68 0,0064 0,0199 0,14 ABCF2 13,37 90,32 0,1706 0,2620 0,26 ABCF3 14,81 100,07 0,8715 0,8900 0,04 ABCG1 4,88 32,98 0,0066 0,0172 0,63 ABCG2 14,60 98,64 0,6315 0,6854 -0,27 ABCG4 14,63 98,83 0,9845 0,9897 0,11 ABCG5 13,90 93,92 0,3919 0,4793 -0,15 ABCG8 9,53 64,35 0,0052 0,0128 0,24 ABHD1 15,46 104,45 0,2419 0,3203 0,31 ABHD12B 16,70 112,79 0,0129 0,0290 0,23 ABHD13 10,06 67,98 0,0307 0,0595 0,35 ABHD14A 15,83 106,92 0,0466 0,0887 -0,33 ABHD14B 15,68 105,92 0,3837 0,4995 -0,22 ABHD2 15,08 101,83 0,9425 0,9574 -0,03 ABHD3 9,47 63,99 0,0004 0,0012 0,01 ABHD4 16,31 110,19 0,0288 0,0607 -0,20 ABHD5 11,37 76,83 0,0060 0,0122 0,21 ABHD6 15,21 102,74 0,5909 0,6876 0,10 ABHD7 12,70 85,81 0,0786 0,1253 0,04 ABHD8 14,19 95,87 0,5085 0,5779 -0,14 ABHD9 12,69 85,72 0,6064 0,7277 -0,13 ABL1 12,40 83,75 0,0005 0,0018 0,08 ABL2 15,97 107,85 0,3798 0,5100 0,30 ABO 19,93 134,63 0,0213 0,0422 -0,04 ABP1 13,12 88,59 0,0861 0,1207 0,30 ABRA 15,54 104,96 0,2187 0,2884 0,34 ABT1 15,08 101,84 0,8544 0,8772 -0,19 ABTB1 6,93 46,84 0,0524 0,1027 0,60 ACAA1 16,44 111,03 0,0002 0,0005 0,08 ACAA2 16,37 110,56 0,1612 0,2517 0,01 ACACA 16,77 113,28 0,1002 0,1833 0,01 ACACB 14,95 101,00 0,9014 0,9206 0,07 ACAD10 15,29 103,28 0,6350 0,6868 0,23 ACAD11 17,92 121,07 0,0216 0,0444 -0,01 ACAD8 11,57 78,15 < 0.0001 < 0.0001 0,00 ACAD9 17,43 117,71 0,0480 0,0765 -0,18 ACADL 15,84 106,96 0,3547 0,4602 0,11 ACADM 16,23 109,66 0,0088 0,0248 0,04 ACADS 16,56 111,89 0,1494 0,2174 0,28 ACADSB 14,57 98,45 0,8933 0,9346 -0,18 ACADVL 15,92 107,51 0,2497 0,3284 -0,04 ACAT1 17,87 120,73 < 0.0001 < 0.0001 0,01 ACAT2 16,39 110,70 0,0221 0,0488 -0,42 ACCN1 10,65 71,90 0,0055 0,0114 0,12 ACCN2 15,12 102,15 0,4895 0,5370 0,04 ACCN3 12,20 82,42 0,0008 0,0022 -0,03 ACCN4 11,80 79,67 0,0057 0,0150 0,25 ACCN5 14,95 100,99 0,5385 0,5875 0,13 ACE 15,57 105,17 0,1284 0,1904 0,09 ACE2 16,32 110,22 0,0275 0,0559 -0,21 ACHE 11,88 80,24 0,2067 0,3112 0,02 ACIN1 14,59 98,57 0,8733 0,9058 0,10 ACLY 11,88 80,21 0,1876 0,2740 0,51 ACMSD 14,24 96,20 0,0881 0,1410 -0,09 ACO1 11,15 75,32 0,0004 0,0012 -0,10 ACO2 12,53 84,61 0,2913 0,3967 0,39 ACOT1 18,05 121,89 0,0005 0,0017 0,28 ACOT11 11,39 76,92 < 0.0001 < 0.0001 0,21 ACOT12 18,33 123,79 0,0052 0,0142 0,10 ACOT2 15,88 107,28 0,0018 0,0052 -0,03 ACOT4 18,45 124,60 < 0.0001 < 0.0001 0,07 ACOT6 15,53 104,87 0,4486 0,5647 -0,15 ACOT7 14,18 95,81 0,7424 0,8008 0,23 ACOT8 11,00 74,31 0,0144 0,0284 0,34 ACOT9 17,03 115,01 0,0030 0,0081 0,18 ACOX1 16,46 111,21 0,3251 0,4053 -0,16 ACOX2 14,65 98,93 0,9340 0,9425 0,51 ACOX3 14,10 95,27 0,0923 0,1695 0,15 ACOXL 12,19 82,32 0,0618 0,0968 0,05 ACP1 11,33 76,51 0,0070 0,0182 0,26 ACP2 7,27 49,12 0,0098 0,0238 0,66 ACP5 11,69 78,98 0,0667 0,1128 0,13 ACP6 15,64 105,64 0,1564 0,2093 0,29 ACPL2 9,92 66,99 0,0100 0,0242 0,33 ACPP 13,81 93,30 0,2085 0,2678 0,21 ACPT 13,81 93,27 0,0881 0,1395 0,25 ACR 14,29 96,54 0,4004 0,4702 -0,02 ACSBG1 15,73 106,24 0,5499 0,6229 0,00 ACSBG2 14,12 95,38 0,4528 0,5605 0,15 ACSF2 12,10 81,72 0,1648 0,2572 -0,05 ACSL1 16,97 114,66 0,0099 0,0229 0,25 ACSL3 15,43 104,20 0,5199 0,5837 -0,16 ACSL4 13,05 88,16 0,0171 0,0351 0,01 ACSL5 15,74 106,29 0,4061 0,4920 0,00 ACSL6 18,21 123,02 0,0020 0,0058 0,38 ACSM1 13,66 92,26 0,0610 0,1089 -0,03 ACSM2B 14,86 100,34 0,9974 0,9974 0,02 ACSM3 20,34 137,38 0,0630 0,1192 0,17 ACSS1 12,35 83,42 0,1153 0,1934 0,12 ACSS2 11,96 80,79 0,1925 0,2648 0,14 ACSS3 13,57 91,63 0,0045 0,0104 0,17 ACTL6A 14,41 97,33 0,7997 0,8300 0,57 ACTN1 12,45 84,07 0,0395 0,0894 0,16 ACTN2 17,69 119,47 0,0231 0,0593 0,01 ACVR1 20,36 137,49 0,0279 0,0518 0,27 ACVR1B 18,66 126,05 0,1012 0,2079 -0,07 ACVR1C 18,47 124,75 0,0680 0,1527 0,17 ACVR2A 18,68 126,17 < 0.0001 < 0.0001 -0,26 ACVR2B 19,00 128,34 0,0482 0,0808 0,14 ACVRL1 20,58 139,00 0,0439 0,1067 0,16 ACY1 8,45 57,11 < 0.0001 0,0001 0,40 ACY3 16,31 110,14 0,3094 0,4054 0,02 ACYP1 14,29 96,52 0,7250 0,7712 -0,19 ACYP2 11,73 79,26 0,0058 0,0169 -0,02 ADA 12,49 84,36 0,0503 0,0902 0,13 ADAD1 15,29 103,26 0,7174 0,7717 0,24 ADAM10 15,34 103,62 0,4493 0,5166 0,17 ADAM11 15,16 102,39 0,4581 0,5174 -0,06 ADAM12 12,87 86,93 0,0082 0,0160 -0,01 ADAM15 15,11 102,07 0,6509 0,6866 0,07 ADAM17 19,05 128,68 0,0037 0,0108 -0,18 ADAM18 13,65 92,19 0,3647 0,4391 -0,19 ADAM19 12,23 82,60 0,0128 0,0237 0,31 ADAM2 14,38 97,12 0,3286 0,4044 0,28 ADAM20 15,46 104,44 0,2558 0,3051 0,04 ADAM21 11,47 77,46 0,0750 0,1258 0,19 ADAM22 11,37 76,80 0,0170 0,0381 -0,12 ADAM23 16,26 109,82 0,0723 0,1228 -0,17 ADAM28 15,18 102,52 0,3437 0,4184 -0,07 ADAM29 12,45 84,10 < 0.0001 < 0.0001 0,19 ADAM30 14,27 96,42 0,0190 0,0409 -0,16 ADAM32 13,67 92,35 0,0359 0,0693 0,05 ADAM33 13,01 87,90 0,0099 0,0246 -0,03 ADAM7 16,32 110,21 0,0113 0,0276 -0,10 ADAM8 13,74 92,83 0,0134 0,0244 0,07 ADAM9 15,19 102,59 0,3343 0,4101 0,30 ADAMDEC1 15,51 104,79 0,3704 0,4445 -0,22 ADAMTS1 15,53 104,89 0,0041 0,0087 -0,20 ADAMTS10 20,32 137,28 0,0001 0,0003 0,23 ADAMTS12 12,58 84,95 0,1508 0,2168 -0,27 ADAMTS13 13,98 94,41 0,1841 0,2534 -0,14 ADAMTS14 19,99 135,04 0,0001 0,0003 -0,25 ADAMTS15 15,59 105,27 0,2028 0,2529 0,01 ADAMTS16 15,01 101,40 0,4336 0,5009 0,08 ADAMTS17 13,14 88,73 0,1202 0,1796 0,12 ADAMTS18 16,62 112,28 0,4554 0,5158 -0,08 ADAMTS19 15,78 106,62 0,0569 0,0804 0,03 ADAMTS2 12,82 86,57 < 0.0001 < 0.0001 0,04 ADAMTS20 15,86 107,16 0,2427 0,3148 -0,14 ADAMTS3 14,65 98,93 0,8365 0,8595 -0,35 ADAMTS4 11,82 79,85 < 0.0001 < 0.0001 0,38 ADAMTS5 11,65 78,66 0,0087 0,0168 0,03 ADAMTS6 16,20 109,43 0,2478 0,2973 0,07 ADAMTS7 11,75 79,38 0,0579 0,1034 0,27 ADAMTS8 14,40 97,29 0,5977 0,6502 -0,06 ADAMTS9 16,21 109,52 0,0004 0,0014 0,01 ADAMTSL1 17,07 115,32 < 0.0001 < 0.0001 0,01 ADAR 13,85 93,54 0,9464 0,9691 -0,48 ADARB1 15,04 101,60 0,8879 0,9092 0,04 ADAT1 13,35 90,18 0,0002 0,0006 0,11 ADAT2 18,08 122,11 0,0314 0,0616 0,04 ADC 15,33 103,57 0,6654 0,7428 0,15 ADCK1 16,64 112,43 0,3306 0,4634 -0,14 ADCK2 12,86 86,84 0,0444 0,0762 0,22 ADCK4 16,81 113,53 0,0042 0,0109 -0,11 ADCK5 11,87 80,19 0,0060 0,0145 0,14 ADCY1 17,00 114,85 0,0658 0,1232 0,32 ADCY10 13,96 94,30 0,5866 0,6631 0,08 ADCY2 15,82 106,86 0,5358 0,5999 0,08 ADCY3 15,49 104,60 0,0279 0,0615 -0,27 ADCY4 18,50 124,99 0,0003 0,0012 -0,06 ADCY5 12,48 84,28 0,4164 0,5028 0,09 ADCY6 13,97 94,35 0,4368 0,5498 0,01 ADCY7 10,89 73,54 0,3536 0,4467 0,49 ADCY8 14,35 96,94 0,5246 0,5839 -0,11 ADCY9 4,24 28,66 0,0356 0,0829 0,70 ADCYAP1R1 13,25 89,49 0,1063 0,2243 0,21 ADD1 17,24 116,43 0,0001 0,0003 -0,22 ADH1A 18,39 124,24 0,0927 0,1447 -0,15 ADH1B 11,40 77,02 0,0875 0,1542 0,11 ADH1C 18,72 126,48 0,0020 0,0051 -0,10 ADH4 12,63 85,34 0,0595 0,1063 0,22 ADH5 17,78 120,08 0,0225 0,0440 0,42 ADH6 16,34 110,35 0,1352 0,2268 -0,08 ADH7 14,97 101,15 0,6763 0,7398 -0,18 ADHFE1 16,26 109,85 0,2730 0,3437 0,03 ADI1 18,90 127,64 < 0.0001 < 0.0001 -0,01 ADK 14,51 98,01 0,8418 0,8832 0,32 ADORA1 24,56 165,89 0,0118 0,0423 -0,03 ADORA2A 10,66 71,99 0,0893 0,2078 -0,17 ADORA2B 19,67 132,85 < 0.0001 0,0001 0,18 ADORA3 8,51 57,49 0,0033 0,0080 0,38 ADPGK 14,90 100,66 0,9651 0,9727 0,07 ADPRH 2,29 15,46 < 0.0001 < 0.0001 0,52 ADPRHL1 15,87 107,17 0,3493 0,4355 0,17 ADPRHL2 16,73 113,03 0,0628 0,1426 0,33 ADRA1A 15,03 101,55 0,8995 0,9138 0,17 ADRA1B 13,93 94,07 0,4403 0,5189 0,01 ADRA1D 11,62 78,47 0,1154 0,2357 -0,02 ADRA2A 14,23 96,15 0,5830 0,6433 -0,02 ADRA2B 18,64 125,90 0,1326 0,2541 0,02 ADRA2C 16,72 112,95 0,4405 0,5189 0,23 ADRB1 19,10 129,02 0,2161 0,3379 -0,18 ADRB2 16,72 112,92 0,3790 0,4710 -0,28 ADRB3
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