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Antioxidants and Second Messengers of Free Radicals
antioxidants Antioxidants and Second Messengers of Free Radicals Edited by Neven Zarkovic Printed Edition of the Special Issue Published in Antioxidants www.mdpi.com/journal/antioxidants Antioxidants and Second Messengers of Free Radicals Antioxidants and Second Messengers of Free Radicals Special Issue Editor Neven Zarkovic MDPI • Basel • Beijing • Wuhan • Barcelona • Belgrade Special Issue Editor Neven Zarkovic Rudjer Boskovic Institute Croatia Editorial Office MDPI St. Alban-Anlage 66 4052 Basel, Switzerland This is a reprint of articles from the Special Issue published online in the open access journal Antioxidants (ISSN 2076-3921) from 2018 (available at: https://www.mdpi.com/journal/ antioxidants/special issues/second messengers free radicals) For citation purposes, cite each article independently as indicated on the article page online and as indicated below: LastName, A.A.; LastName, B.B.; LastName, C.C. Article Title. Journal Name Year, Article Number, Page Range. ISBN 978-3-03897-533-5 (Pbk) ISBN 978-3-03897-534-2 (PDF) c 2019 by the authors. Articles in this book are Open Access and distributed under the Creative Commons Attribution (CC BY) license, which allows users to download, copy and build upon published articles, as long as the author and publisher are properly credited, which ensures maximum dissemination and a wider impact of our publications. The book as a whole is distributed by MDPI under the terms and conditions of the Creative Commons license CC BY-NC-ND. Contents About the Special Issue Editor ...................................... vii Preface to ”Antioxidants and Second Messengers of Free Radicals” ................ ix Neven Zarkovic Antioxidants and Second Messengers of Free Radicals Reprinted from: Antioxidants 2018, 7, 158, doi:10.3390/antiox7110158 ............... -
Aldrich Raman
Aldrich Raman Library Listing – 14,033 spectra This library represents the most comprehensive collection of FT-Raman spectral references available. It contains many common chemicals found in the Aldrich Handbook of Fine Chemicals. To create the Aldrich Raman Condensed Phase Library, 14,033 compounds found in the Aldrich Collection of FT-IR Spectra Edition II Library were excited with an Nd:YVO4 laser (1064 nm) using laser powers between 400 - 600 mW, measured at the sample. A Thermo FT-Raman spectrometer (with a Ge detector) was used to collect the Raman spectra. The spectra were saved in Raman Shift format. Aldrich Raman Index Compound Name Index Compound Name 4803 ((1R)-(ENDO,ANTI))-(+)-3- 4246 (+)-3-ISOPROPYL-7A- BROMOCAMPHOR-8- SULFONIC METHYLTETRAHYDRO- ACID, AMMONIUM SALT PYRROLO(2,1-B)OXAZOL-5(6H)- 2207 ((1R)-ENDO)-(+)-3- ONE, BROMOCAMPHOR, 98% 12568 (+)-4-CHOLESTEN-3-ONE, 98% 4804 ((1S)-(ENDO,ANTI))-(-)-3- 3774 (+)-5,6-O-CYCLOHEXYLIDENE-L- BROMOCAMPHOR-8- SULFONIC ASCORBIC ACID, 98% ACID, AMMONIUM SALT 11632 (+)-5-BROMO-2'-DEOXYURIDINE, 2208 ((1S)-ENDO)-(-)-3- 97% BROMOCAMPHOR, 98% 11634 (+)-5-FLUORODEOXYURIDINE, 769 ((1S)-ENDO)-(-)-BORNEOL, 99% 98+% 13454 ((2S,3S)-(+)- 11633 (+)-5-IODO-2'-DEOXYURIDINE, 98% BIS(DIPHENYLPHOSPHINO)- 4228 (+)-6-AMINOPENICILLANIC ACID, BUTANE)(N3-ALLYL)PD(II) CL04, 96% 97 8167 (+)-6-METHOXY-ALPHA-METHYL- 10297 ((3- 2- NAPHTHALENEACETIC ACID, DIMETHYLAMINO)PROPYL)TRIPH 98% ENYL- PHOSPHONIUM BROMIDE, 12586 (+)-ANDROSTA-1,4-DIENE-3,17- 99% DIONE, 98% 13458 ((R)-(+)-2,2'- 963 (+)-ARABINOGALACTAN BIS(DIPHENYLPHOSPHINO)-1,1'- -
1 Abietic Acid R Abrasive Silica for Polishing DR Acenaphthene M (LC
1 abietic acid R abrasive silica for polishing DR acenaphthene M (LC) acenaphthene quinone R acenaphthylene R acetal (see 1,1-diethoxyethane) acetaldehyde M (FC) acetaldehyde-d (CH3CDO) R acetaldehyde dimethyl acetal CH acetaldoxime R acetamide M (LC) acetamidinium chloride R acetamidoacrylic acid 2- NB acetamidobenzaldehyde p- R acetamidobenzenesulfonyl chloride 4- R acetamidodeoxythioglucopyranose triacetate 2- -2- -1- -β-D- 3,4,6- AB acetamidomethylthiazole 2- -4- PB acetanilide M (LC) acetazolamide R acetdimethylamide see dimethylacetamide, N,N- acethydrazide R acetic acid M (solv) acetic anhydride M (FC) acetmethylamide see methylacetamide, N- acetoacetamide R acetoacetanilide R acetoacetic acid, lithium salt R acetobromoglucose -α-D- NB acetohydroxamic acid R acetoin R acetol (hydroxyacetone) R acetonaphthalide (α)R acetone M (solv) acetone ,A.R. M (solv) acetone-d6 RM acetone cyanohydrin R acetonedicarboxylic acid ,dimethyl ester R acetonedicarboxylic acid -1,3- R acetone dimethyl acetal see dimethoxypropane 2,2- acetonitrile M (solv) acetonitrile-d3 RM acetonylacetone see hexanedione 2,5- acetonylbenzylhydroxycoumarin (3-(α- -4- R acetophenone M (LC) acetophenone oxime R acetophenone trimethylsilyl enol ether see phenyltrimethylsilyl... acetoxyacetone (oxopropyl acetate 2-) R acetoxybenzoic acid 4- DS acetoxynaphthoic acid 6- -2- R 2 acetylacetaldehyde dimethylacetal R acetylacetone (pentanedione -2,4-) M (C) acetylbenzonitrile p- R acetylbiphenyl 4- see phenylacetophenone, p- acetyl bromide M (FC) acetylbromothiophene 2- -5- -
Environmental Protection Agency § 117.3
Environmental Protection Agency § 117.3 (4) Applicability date. This paragraph TABLE 117.3—REPORTABLE QUANTITIES OF (i) is applicable beginning on February HAZARDOUS SUBSTANCES DESIGNATED PUR- 6, 2020. SUANT TO SECTION 311 OF THE CLEAN (j) Process waste water means any WATER ACT—Continued water which, during manufacturing or Cat- RQ in pounds processing, comes into direct contact Material egory (kilograms) with or results from the production or use of any raw material, intermediate Ammonium benzoate ...................... D ...... 5,000 (2,270) Ammonium bicarbonate .................. D ...... 5,000 (2,270) product, finished product, byproduct, Ammonium bichromate ................... A ....... 10 (4.54) or waste product. Ammonium bifluoride ...................... B ....... 100 (45.4) Ammonium bisulfite ......................... D ...... 5,000 (2,270) [44 FR 50776, Aug. 29, 1979, as amended at 58 Ammonium carbamate .................... D ...... 5,000 (2,270) FR 45039, Aug. 25, 1993; 65 FR 30904, May 15, Ammonium carbonate ..................... D ...... 5,000 (2,270) 2000; 80 FR 37112, June 29, 2015; 83 FR 5208, Ammonium chloride ........................ D ...... 5,000 (2,270) Feb. 6, 2018] Ammonium chromate ...................... A ....... 10 (4.54) Ammonium citrate dibasic ............... D ...... 5,000 (2,270) Ammonium fluoborate ..................... D ...... 5,000 (2,270) § 117.2 Abbreviations. Ammonium fluoride ......................... B ....... 100 (45.4) NPDES equals National Pollutant Ammonium hydroxide ..................... C -
Wednesday May 26, 1999
5±26±99 Vol. 64 No. 101 Wednesday Pages 28333±28712 May 26, 1999 federal register 1 VerDate 06-MAY-99 21:29 May 25, 1999 Jkt 183247 PO 00000 Frm 00001 Fmt 4710 Sfmt 4710 E:\FR\FM\26MYWS.XXX pfrm03 PsN: 26MYWS II Federal Register / Vol. 64, No. 101 / Wednesday, May 26, 1999 The FEDERAL REGISTER is published daily, Monday through SUBSCRIPTIONS AND COPIES Friday, except official holidays, by the Office of the Federal Register, National Archives and Records Administration, PUBLIC Washington, DC 20408, under the Federal Register Act (44 U.S.C. Subscriptions: Ch. 15) and the regulations of the Administrative Committee of Paper or fiche 202±512±1800 the Federal Register (1 CFR Ch. I). The Superintendent of Assistance with public subscriptions 512±1806 Documents, U.S. Government Printing Office, Washington, DC 20402 is the exclusive distributor of the official edition. General online information 202±512±1530; 1±888±293±6498 Single copies/back copies: The Federal Register provides a uniform system for making available to the public regulations and legal notices issued by Paper or fiche 512±1800 Federal agencies. These include Presidential proclamations and Assistance with public single copies 512±1803 Executive Orders, Federal agency documents having general FEDERAL AGENCIES applicability and legal effect, documents required to be published Subscriptions: by act of Congress, and other Federal agency documents of public Paper or fiche 523±5243 interest. Assistance with Federal agency subscriptions 523±5243 Documents are on file for public inspection in the Office of the Federal Register the day before they are published, unless the issuing agency requests earlier filing. -
The Asymmetric Synthesis of Styrene-Oxide and Its Reactions with Dialkylmagnesium Reagents and Boron Hydrides
University of New Hampshire University of New Hampshire Scholars' Repository Doctoral Dissertations Student Scholarship Summer 1971 THE ASYMMETRIC SYNTHESIS OF STYRENE-OXIDE AND ITS REACTIONS WITH DIALKYLMAGNESIUM REAGENTS AND BORON HYDRIDES RONALD LEROY ATKINS Follow this and additional works at: https://scholars.unh.edu/dissertation Recommended Citation ATKINS, RONALD LEROY, "THE ASYMMETRIC SYNTHESIS OF STYRENE-OXIDE AND ITS REACTIONS WITH DIALKYLMAGNESIUM REAGENTS AND BORON HYDRIDES" (1971). Doctoral Dissertations. 964. https://scholars.unh.edu/dissertation/964 This Dissertation is brought to you for free and open access by the Student Scholarship at University of New Hampshire Scholars' Repository. It has been accepted for inclusion in Doctoral Dissertations by an authorized administrator of University of New Hampshire Scholars' Repository. For more information, please contact [email protected]. 72-3736 ATKINS, Ronald Leroy, 1939- THE ASYMMETRIC SYNTHESIS OF STYRENE OXIDE AND ITS REACTIONS WITH DIALKYLMAGNESIUM REAGENTS AND BORON HYDRIDES. University of New Hampshire, Ph.D., 1971 Chemistry, organic University Microfilms, A XEROX Company, Ann Arbor, Michigan © 1971 Ronald LeRoy Atkina ALL RIGHTS RESERVED THE ASYMMETRIC SYNTHESIS OF STYRENE OXIDE AND ITS REACTIONS WITH DIALKYLMAGNESIUM REAGENTS AND BORON HYDRIDES by RONALD L. ATKINS B. S., The University of Wyoming, 1966 M. S., The University of Wyoming, 1968 A THESIS Submitted to the University of New Hampshire In Partial Fulfillment of The Requirements for the Degree of DOCTOR OF PHILOSOPHY Graduate School Department of Chemistry August, 1971 This thesis has been examined and approved. f b w < M & > YUffvyido— The^js Director, James D. Morrison Asspaiate Professor of Chemistry & L DJitdsh-iU. _____ Colin D. -
Biomedical Applications of Polymeric Cryogels
applied sciences Review Biomedical Applications of Polymeric Cryogels Monireh Bakhshpour 1, Neslihan Idil 2, I¸sıkPerçin 2 and Adil Denizli 1,* 1 Department of Chemistry, Faculty of Science, Hacettepe University, Ankara 06800, Turkey; [email protected] 2 Department of Biology, Faculty of Science, Hacettepe University, Ankara 06800, Turkey; [email protected] (N.I.); [email protected] (I.P.) * Correspondence: [email protected]; Tel.: +90-312-297-7983 Received: 31 December 2018; Accepted: 4 February 2019; Published: 7 February 2019 Featured Application: This study presents the comprehensive applications of polymeric cryogels in the field of biomedicine. To the best of our knowledge, this review is one of the most pioneering paper comparatively explains the biomedical applications of cryogels in detail. Abstract: The application of interconnected supermacroporous cryogels as support matrices for the purification, separation and immobilization of whole cells and different biological macromolecules has been well reported in literature. Cryogels have advantages over traditional gel carriers in the field of biochromatography and related biomedical applications. These matrices nearly mimic the three-dimensional structure of native tissue extracellular matrix. In addition, mechanical, osmotic and chemical stability of cryogels make them attractive polymeric materials for the construction of scaffolds in tissue engineering applications and in vitro cell culture, separation materials for many different processes such as immobilization of biomolecules, capturing of target molecules, and controlled drug delivery. The low mass transfer resistance of cryogel matrices makes them useful in chromatographic applications with the immobilization of different affinity ligands to these materials. Cryogels have been introduced as gel matrices prepared using partially frozen monomer or polymer solutions at temperature below zero. -
Used at Rocky Flats
. TASK 1 REPORT (Rl) IDENTIFICATION OF CHEMICALS AND RADIONUCLIDES USED AT ROCKY FLATS I PROJECT BACKGROUND ChemRisk is conducting a Rocky Flats Toxicologic Review and Dose Reconstruction study for The Colorado Department of Health. The two year study will be completed by the fall of 1992. The ChemRisk study is composed of twelve tasks that represent the first phase of an independent investigation of off-site health risks associated with the operation of the Rocky Flats nuclear weapons plant northwest of Denver. The first eight tasks address the collection of historic information on operations and releases and a detailed dose reconstruction analysis. Tasks 9 through 12 address the compilation of information and communication of the results of the study. Task 1 will involve the creation of an inventory of chemicals and radionuclides that have been present at Rocky Flats. Using this inventory, chemicals and radionuclides of concern will be selected under Task 2, based on such factors as the relative toxicity of the materials, quantities used, how the materials might have been released into the environment, and the likelihood for transport of the materials off-site. An historical activities profile of the plant will be constructed under Task 3. Tasks 4, 5, and 6 will address the identification of where in the facility activities took place, how much of the materials of concern were released to the environment, and where these materials went after the releases. Task 7 addresses historic land-use in the vicinity of the plant and the location of off-site populations potentially affected by releases from Rocky Flats. -
Phytochem Referenzsubstanzen
High pure reference substances Phytochem Hochreine Standardsubstanzen for research and quality für Forschung und management Referenzsubstanzen Qualitätssicherung Nummer Name Synonym CAS FW Formel Literatur 01.286. ABIETIC ACID Sylvic acid [514-10-3] 302.46 C20H30O2 01.030. L-ABRINE N-a-Methyl-L-tryptophan [526-31-8] 218.26 C12H14N2O2 Merck Index 11,5 01.031. (+)-ABSCISIC ACID [21293-29-8] 264.33 C15H20O4 Merck Index 11,6 01.032. (+/-)-ABSCISIC ACID ABA; Dormin [14375-45-2] 264.33 C15H20O4 Merck Index 11,6 01.002. ABSINTHIN Absinthiin, Absynthin [1362-42-1] 496,64 C30H40O6 Merck Index 12,8 01.033. ACACETIN 5,7-Dihydroxy-4'-methoxyflavone; Linarigenin [480-44-4] 284.28 C16H12O5 Merck Index 11,9 01.287. ACACETIN Apigenin-4´methylester [480-44-4] 284.28 C16H12O5 01.034. ACACETIN-7-NEOHESPERIDOSIDE Fortunellin [20633-93-6] 610.60 C28H32O14 01.035. ACACETIN-7-RUTINOSIDE Linarin [480-36-4] 592.57 C28H32O14 Merck Index 11,5376 01.036. 2-ACETAMIDO-2-DEOXY-1,3,4,6-TETRA-O- a-D-Glucosamine pentaacetate 389.37 C16H23NO10 ACETYL-a-D-GLUCOPYRANOSE 01.037. 2-ACETAMIDO-2-DEOXY-1,3,4,6-TETRA-O- b-D-Glucosamine pentaacetate [7772-79-4] 389.37 C16H23NO10 ACETYL-b-D-GLUCOPYRANOSE> 01.038. 2-ACETAMIDO-2-DEOXY-3,4,6-TRI-O-ACETYL- Acetochloro-a-D-glucosamine [3068-34-6] 365.77 C14H20ClNO8 a-D-GLUCOPYRANOSYLCHLORIDE - 1 - High pure reference substances Phytochem Hochreine Standardsubstanzen for research and quality für Forschung und management Referenzsubstanzen Qualitätssicherung Nummer Name Synonym CAS FW Formel Literatur 01.039. -
Plant Secondary Metabolites .Pdf
PLANT SECONDARY METABOLITES W W W . T R C - C A N A D A . C O M +1 (416) 665-9696 www.trc-canada.com 2 Brisbane Road, Toronto [email protected] Plant Secondary Metabolites Product CAS No CAT No Acanthopanax senticosides B 114902-16-8 Please Inquire Acetyl resveratrol 42206-94-0 R150055 Acetylshikonin 24502-78-1 Please Inquire Acronycine 7008-42-6 Please Inquire Acteoside 61276-17-3 V128000 Agrimol B 55576-66-4 Please Inquire Alisol-B-23-acetate 26575-95-1 A535970 Alisol-C-monoacetate 26575-93-9 Please Inquire Alizarin 72-48-0 A536600 Alkannin 517-88-4 Please Inquire Allantoin 97-59-6 A540500 Allantoin-13C2,15N4 1219402-51-3 A540502 Alliin 556-27-4 A543530 Aloe emodin 481-72-1 A575400 Aloe-emodin-d5 1286579-72-3 A575402 Aloenin A 38412-46-3 Please Inquire Aloin A 1415-73-2 A575415 Amentoflavone 1617-53-4 A576420 Amygdalin 29883-15-6 A576840 Andrographolide 5508-58-7 A637475 Angelicin 523-50-2 A637575 Anhydroicaritin 118525-40-9 I163700 Anisodamine 55869-99-3 Please Inquire Anthraquinone 84-65-1 A679245 Anthraquinone-D8 10439-39-1 A679247 Apigenin 520-36-5 A726500 Apigenin-d5 263711-74-6 A726502 Araloside X 344911-90-6 Please Inquire www.trc-canada.com I +1 (416) 665-9696 I [email protected] Plant Secondary Metabolites Arbutin 497-76-7 A766510 Arbutin-13C6 A766512 Arctigenin 7770-78-7 A766580 Arctiin 20362-31-6 A766575 Aristolochic acid I 313-67-7 A771300 Aristolochic acid II 475-80-9 A771305 Aristolochic acid sodium salt 10190-99-5 Please Inquire Aristololactam 13395-02-3 A771200 Artemisinin 63968-64-9 A777500 Artemisinin-d3 176652-07-6 -
Appendix C: Natural Resources and Environmental Protection
A Appendix C: P Natural Resources P and Environmental E Protection Act (NREPA) Part 31 – N Part 5 Rules D • Applicability Flow Chart I • Part 5 Rules with Notes X C APPENDIX C: NREPA Part 31 – Part 5 Rules Applicability Flow Chart - Part 5 Rules Spillage of Oil and Polluting Materials Review the administrative rules (R 324.2001 – R 324.2009) on the following pages and ask the questions below to determine if the Part 5 requirements apply. Does the facility meet the definition of an oil storage or on-land facility per R 324.2001 (f) or (g)? No Yes Does the facility have polluting materials that all meet the small container exemption or are regulated by (and in compliance with) another Yes Not subject to Part 5 requirements. program listed in R 324.2003 excluding R 324.2003 (1)(b)? No Does the facility have polluting materials in regulated Threshold Management Quantities (TMQs) per R 324.2002 (f)? No Polluting materials include mixtures containing 1% or more, by weight, of any substances listed below. SALT LISTED CHEMICALS OIL R 324.2009 Solid form - 5 tons Single container or tank having 660 gallon storage or Liquid form - 1,000 gallons Outdoors – 440 pounds capacity Indoors – 2,200 pounds Total capacity of 1,320 gallons above ground storage REQUIREMENTS o Pollution Incident Prevention Plan (PIPP) – R 324.2006 REQUIREMENTS Including notification requirements to EGLE , local health o Use Area & Indoor Storage – R 324.2005 department, and local emergency planning committee o Surveillance – R 324.2004 o Secondary Containment – R 324.2005 o -
A Study for Health Hazard Evaluation of Methylene Chloride Evaporated from the Tear Gas Mixture
Saf Health Work 2010;1:98-101 | DOI:10.5491/SHAW.2010.1.1.98 pISSN : 2093-7911 eISSN : 2093-7997 Case Report A Study for Health Hazard Evaluation of Methylene Chloride Evaporated from the Tear Gas Mixture Seung-Hyun PARK, Eun-Kyo CHUNG, Gwang-Yong YI, Kwang-Jae CHUNG, Jung-Ah SHIN and In-Seop LEE Department of Occupational Environment Research, Occupational Safety and Health Research Institute, KOSHA, Incheon, Korea This study explored the health hazard of those exposed to methylene chloride by assessing its atmospheric concentration when a tear gas mixture was aerially dispersed. The concentration of methylene chloride ranged from 311.1–980.3 ppm (geometric mean, 555.8 ppm), 30 seconds after the dispersion started. However, the concentration fell rapidly to below 10 ppm after dispersion was completed. The concentration during the dispersion did not surpass the National Institute for Occupational Safety and Health ‘immediately dangerous to life or health’ value of 2,300 ppm, but did exceed the American Conference of Governmental Industrial Hygienists excursion limit of 250 ppm. Since methylene chloride is highly volatile (vapor pressure, 349 mmHg at 20oC), the post- dispersion atmospheric concentration can rise instantaneously. Moreover, the o-chlorobenzylidenemalononitrile formulation of tear gas (CS gas) is an acute upper respiratory tract irritant. Therefore, tear gas mixtures should be handled with delicate care. Key Words: Methylene chloride, CS tear gas, Tear gas mixture, Health hazard evaluation Introduction Despite this long history of use, CS gas has recently come under greater scrutiny since it can be applied as a mixture that Tear gases such as o-chlorobenzylidenemalononitrile (CS), contains a suspected human carcinogen, methylene chloride.