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Home , Alfonso Valencia, Anders Krogh, Chris Sander (scientist), David Baker (biochemist), Ewan Birney, Gunnar von Heijne

ISCB NEWSLETTER FOCUS ISSUE

{contents} President’s Letter 2 Member Involvement Encouraged

Register for ISMB 2002 3 Registration and Tutorial Update

Host ISMB 2004 or 2005 3

David Baker 4 2002 Recipient

Overton Endowment 4

ISMB 2002 Committees 4

ISMB 2002 Opportunities 5 Sponsor and Exhibitor Benefits

Best Paper Award by SGI 5

ISMB 2002 SIGs 6 New Program for 2002

ISMB Goes Down Under 7 Planning Underway for 2003

Hot Jobs! Top Companies! 8 ISMB 2002 Job Fair

ISCB Board Nominations 8

Bioinformatics Pioneers 9 ISMB 2002 Keynote Speakers

Invited Editorial 10 : in Europe

Software Recommendations11 ISCB Software Statement volume 5. issue 2. summer 2002 Community Development 12 ISCB’s Regional Affiliates Program

ISCB Staff Introduction 12

Fellowship Recipients 13 Awardees at RECOMB 2002

Events and Opportunities 14 Bioinformatics events world wide

INTERNATIONAL SOCIETY FOR A NOTE FROM ISCB PRESIDENT

This newsletter is packed with information on development and dissemination of bioinfor- the ISMB2002 conference. With over 200 matics. Issues arise from recommendations paper submissions and over 500 poster submis- made by the Society’s committees, Board of sions, the conference promises to be a scientific Directors, and membership at large. Important feast. On behalf of the ISCB’s Directors, staff, issues are defined as motions and are discussed

EXECUTIVE COMMITTEE and membership, I would like to thank the by the Board of Directors on a bi-monthly Philip E. Bourne, Ph.D., President organizing committee, local organizing com- teleconference. Motions that pass are enacted Michael Gribskov, Ph.D., mittee, and program committee for their hard by the Executive Committee which also serves Vice President work preparing for the conference. Having co- as an oversight body for the Society office and Anna Tramontano, Ph.D., chaired ISMB 2000, I know how much effort staff. I meet with the Society staff once a week Vice President must be directed away from research and and am continuously in contact via email to David Rocke, Ph.D., Treasurer teaching to make ISMB happen. Thank you. track progress and to help as needed. Barbara Bryant, Ph.D., Secretary ISCB BOARD In the previous newsletter, the Society’s history Much of the work for the Society is done in Russ B.Altman, MD, Ph.D. was discussed (www.iscb.org/newsletter5-1/ committees; members are encouraged to con- Søren Brunak, Ph.D. history.html). The article describes how the tact committee chairs or to join committees to Julio Collado-Vides, Ph.D. Society began as a means to manage the ISMB actively share their ideas with the entire , Ph.D. meeting. ISCB now plays many more roles to Society. Members who wish become more offi- Dietlind L. Gerloff, Ph.D. support our worldwide. Since I suspect cially involved may seek nomination to the Winston Hide, Ph.D. many members are unaware of how these roles Board or Executive Committee by writing to Desmond G. Higgins, Ph.D., are carried out, let me elaborate a little here. [email protected]. Board members are , Ph.D. This is particularly timely information, as ISCB elected by the existing Board for a three year , D.Sc. is actively seeking nominations from interested term, whereas Executive Committee members Peter D. Karp, Ph.D. scientists to volunteer their time, help run the are elected for two years by the membership. Toni Kazic, Ph.D. Society, and make a difference to our science. Teri E.Klein, Ph.D. With elections occurring in the fall; now is the , Ph.D. As the column to the left shows, the Society time to step forward and become involved. Hershel M. Safer, Ph.D. consists of an Executive Committee, Board of ISCB is particularly interested in involving Donna K. Slonim, Ph.D. Directors, and Society staff. Not shown, are young scientists and those from regions of the David J. States, M.D., Ph.D. the individual committees which can be found globe where bioinformatics is emerging. I am Gary D. Stormo, Ph.D. at www.iscb.org/committees.shtml. The be happy to address questions members have Masaru (Tommy) Tomita,Ph.D. Executive Committee holds a monthly telecon- about becoming involved either now by email , Ph.D. ference to discuss issues important to the ([email protected]) or in person at ISMB 2002. , Ph.D.

Tandy Warnow, Ph.D. ISCB Staff Mike Waterman, Ph.D. (clockwise from the far left): Cathy H.Wu, Ph.D. Josh Polterock, Cassie Ferguson, BJ Morrison SOCIETY STAFF McKay, Stephanie Kim Baldridge, Ph.D., Staff Oversight Hagstrom, Jennifer Cassie Ferguson, Writer Matthews,Tracy Zhao, Chris Smith, Phil Bourne, Stephanie Hagstrom, (not pictured: Kim Conference Coordinator Baldridge) Jennifer Matthews, Design BJ Morrison McKay, Administrative Officer Josh Polterock, Webmaster Chris Smith, Ph.D. Finance 2 Tracy Zhao, Programming INTERNATIONAL SOCIETY FOR COMPUTATIONAL BIOLOGY REGISTER NOW FOR ISMB 2002

ISMB 2002 Registration Now Open For more information about the ISMB 2002 REQUEST FOR www.ismb02.org/regis.htm tutorials, visit www.ismb02.org/tutorial.htm. PROPOSALS TO HOST Save US$100 by registering by June 28, 2002. THE ISMB 2004 AND Note: previous ISMB conferences have sold Morning Tutorials (8:30-12:30) 2005 CONFERENCES out one week after the early registration date. • Introduction to Perl Programming for ISCB is now accepting pro- Bioinformatics. Instructor: James Tisdall posals from potential organ- Registration Fees • Introduction to Computational Sequence izing committees to host The conference fees include all scientific ses- Analysis. Instructor: Frédérique Galisson future ISMB conferences. sions, poster session, exhibit hall entrance, • Molecular Modeling: Building a 3-D Submissions must be breakfasts, lunches, receptions, and one copy Structure from Its Sequence. Instructor: Shoba received by July 19, 2002. of the ISMB 2002 proceedings. Ranganathan For more information, please access the ISCB web- • DNA Microarrays and Regulation. On or Before June 28, 2002 site conference page Instructor: Academia: US$415 (ISCB members) (www.iscb.org/conferences.html) • Relational Databases for Biologists. Instructors: US$480 (Non-ISCB members) or contact Stephanie Aaron Mackey and William R. Pearson Student: US$300 (ISCB members) Hagstrom: US$350 (Non-ISCB members) • A Primer on Metabolic Pathway Analysis. [email protected]. Instructor: Eberhard O. Voit Corporate: US$650 (ISCB members) • Information Extraction from Biomedical US$715 (Non-ISCB members) Literature. Instructor: Dietrich Schuhmann, After June 28, 2002 et. al. Academia: US$515 (ISCB members) Afternoon Tutorials (13:30-17:30) US$580 (Non-ISCB members) • Perl and Bioperl: Tools for Automated Analysis Student: US$400 (ISCB members) of Biological Sequence Data. Instructor: Peter CONTACT US$450 (Non-ISCB members) Schattner INFORMATION Corporate: US$750 (ISCB members) • Pattern Discovery in Biosequences. Instructor: ISCB questions, comments, and US$815 (Non-ISCB members) Stefano Lonardi suggestions may be posted to: • Protein Classification and Meta-organization. ISCB c/o San Diego ISMB Registration Methods for Global Organization of the Protein Supercomputer Center Phone: +1-847-518-1708 Universe. Instructor: Golan Yona UC San Diego Fax: +1-847-518-0735 • In silico Analysis of Gene Regulatory Sequences. 9500 Gilman Drive Tutorial Sessions (August 3, 2002) Towards Target Gene Identification. Instructors: La Jolla, CA 92093-0505 USA Individuals may register for one or two option- Alexander Kel and Edgar Wingender phone: +1-858-822-0852 al tutorials. There will be maximum seven (7) • Functional in 4 Hours: A Practical email: [email protected] concurrent sessions in the morning and Guide to Creating Your Own High-Throughput internet: www.iscb.org eight (8) maximum concurrent sessions in the Pipeline. Instructors: Atul Butte and Isaac For specific queries, please afternoon. Please note: Tutorials may only Kohane refer to the following: accommodate a limited number of partici- • Heterogeneous Data and Integration Membership: pants, consequently, some tutorials may sell in Bioinformatics. Instructors: Barbara [email protected] out. It is recommended that participants sign Eckman, Julia Rice, and William Swope Corporate: up as soon as possible. • Modelling Biological Data in Hierarchies. [email protected] Price for one tutorial: US$85 Instructors: Graham Kemp and Peter Gray Sponsorship: [email protected] Price for two tutorials: US$130 • . Instructor:

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Summer 2002 Newsletter www.iscb.org 2002 OVERTON PRIZE The Overton Prize was established by the The ISCB thanks the following indi- ISCB in memory of G. Christian Overton, a viduals for all their support, dedica- major contributor to the field of bioinformat- tion, and commitment to producing ics and member of the ISCB Board of to the ISMB 2002 conference. Directors who died unexpectedly in 2000. The ISMB 2002 ORGANIZING prize is awarded for outstanding accomplish- COMMITTEE ment to a scientist in the early- to mid- stage David Wishart (Chair), University of his or her career who has already made a of Alberta, Canada significant contribution to the field of compu- Søren Brunak, Technical University of , Denmark tational biology through research, education, Julio Collado-Vides*, National service, or a combination of the three. The Autonomous University of Mexico, first Overton Prize was awarded last year to Mexico of the Massachusetts Frédérique Galisson*, University of Institute of Technology for his work identify- 2002 Overton Prize Recipient, David Baker Lausanne, Switzerland ing and modeling in higher eukaryotic (Photo credit: /Mary Levin) Warren Gallin, University of . Alberta, Canada established a record of publications in protein Janice Glasgow*, Queen's University, The 2002 Awards Committee was chaired by folding and outstanding structure prediction Canada David States, and included Donna Slonim, using both computational and experimental Russ Greiner, University of Alberta, Søren Brunak, Mike Waterman, Anders approaches. Canada Krogh, and Larry Hunter. In March 2002, François Major, University of Baker will present a keynote address at this Montreal, Canada members of the Society were invited to submit year’s Intelligent Systems for Molecular *, Columbia nominations to the Awards committee for the University, USA 2002 Overton Prize. Nominees from around Biology (ISMB) conference in Edmonton, Christoph Sensen, University of the globe were considered. Several outstanding Alberta, Canada, on Wednesday, August 7th, Calgary, Canada nominations were received, highlighting the the final day of the conference. ISMB 2002 LOCAL growing talent in bioinformatics. ORGANIZING COMMITTEE David Wishart (Chair), University The Awards Committee unanimously selected OVERTON PRIZE of Alberta, Canada David Baker, Howard Hughes Medical ENDOWMENT Warren Gallin, University of Institute (HHMI) Investigator and associate Alberta, Canada professor at the University of Washington, in OPPORTUNITIES Russ Greiner, University of Alberta, recognition of his outstanding contributions in ISCB continues to solicit contributions toward Canada genomics. His computational technique the endowment of the annual Overton Prize. Steven Leard, Marketwhys Corp., known as the “Rosetta algorithm,” predicts Contributions at the level of $5,000 will be Edmonton, Canada protein folds. He continues to extend and acknowledged as Principal Sponsors and all Bob Parker, University of Alberta, contributions at the level of $1,000 or more Canada apply his work to drug design, , and will be acknowledged as Sponsors in a Mark Ragan, University of health care. Queensland, Australia brochure distributed at each years award of the Karim Sayani, BioAlberta, Canada Baker has previously won the HHMI’s prize. The ISCB is a tax-exempt organization Haiyan Zhang, University of Alberta, Assistant Investigator Award, as well as Young and contributions are tax deductible. Canada Investigator Awards from the Protein Society, the Beckman Foundation, and the National * also a member of the ISMB 2002 Scientific Committee Science Foundation. Since 1988, Baker has

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INTERNATIONAL SOCIETY FOR COMPUTATIONAL BIOLOGY ISMB 2002 SPONSORSHIP & EXHIBITOR OPPORTUNITIES

ISMB 2002 is the premiere event in computa- Conference Supporters/Travel ISMB BEST PAPER tional biology and is known as an outstanding Fellowship AWARD BY SGI The ISMB Best Paper Award opportunity for vendors and exhibitors to • Alberta Government: Alberta by SGI will be presented to highlight their products. To maximize Science and Research an outstanding paper sub- exhibitor exposure, the ISMB 2002 Conference Authority mitted to ISMB 2002.The Exhibition will be held together with the con- • Alberta Heritage Foundation for Medical finalists are: ference’s poster sessions. The combination of Research • Pier Luigi Martelli, Piero poster sessions, food courts and high quality • Hewlett-Packard Fariselli,Anders Krogh, exhibition space will ensure maximal exposure • IBM Life Sciences : A sequence for your company at this year’s conference. • International Society for Computational profile based HMM for pre- Biology To obtain additional information on how to dicting and discriminating • National Institute of Health participate in the ISMB conference as a spon- beta barrel membrane • National Science Foundation sor, please visit: www.ismb02.org/corporate.html, • Daniel Fasulo,Aaron • PENCE The Canadian Protein Engineering or contact Stephanie Hagstrom, ISCB Halpern, Ian Dew, Clark Network +1-858-623-0050 or [email protected]. Mobarry: Efficiently • Structural Genomix, Inc. Detecting Polymorphisms ISMB 2002 Sponsors and Exhibitors to date: • University of Alberta During The Fragment • US Department of Energy Assembly Process Platinum Sponsors Exhibiting Companies • Gianluca Pollastri, Pierre • Hewlett-Packard • American Medical Informatics Association Baldi: Prediction of Contact • IBM Life Sciences • Biomax Informatics AG Maps by Recurrent Neural • Cambridge University Press Network Architectures and Gold Sponsors • Institute of Biomolecular Design, Project Hidden Context Propagation • Alberta Government: Ministry of Cybercell From All Four Cardinal Corners Innovation and Science • ExerGen Initial nominations were • GeneData • InforSense provided by the program • Gene Logic • John Wiley & Sons committee and senior • Genome Prairie • O’Reilly & Associates reviewers for the confer- • ICORE • Platform Computing, Inc. ence.The three finalists • LionBioscience • Protein Data Bank were chosen by the com- • SGI • Science Factory GMBH mittee’s co-chairs after • Sun Microsystems • Silicon Genetics • University of Alberta reviewing all nominations. • Spotfire, Inc. The winner will be selected • The MIT Press Silver Sponsors by a subset of the senior • Accelrys, Inc. review committee based on the written paper as well as • University of Calgary oral presentation at the conference.The award will be presented after the final session of ISMB.

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Summer 2002 Newsletter www.iscb.org ISMB 2002 SPECIAL INTEREST GROUP MEETINGS

Over the past 10 years, a number of small- several long presentations (45 minutes), fol- Bio-ontologies: August 8 (9:00-17:00) er, more specialized meetings in computa- lowed by a panel discussion. One of the Westin Hotel tional biology have become regularly asso- aims of this year’s meeting is to promote The fifth annual Bio-Ontologies meeting ciated with the ISMB annual meetings. interaction between the physics and engi- will be held the day after ISMB. Recent ISMB is pleased to have several special neering communities, and the computer meetings have been well-attended and live- interest group meetings associated with the science and biology communities. ly affairs. This year’s theme is a Semantic 2002 conference. Web of Bioinformatics Resources, mirror- Text-Mining: August 2 (9:00-17:00) ing the push by the W3C on the Semantic Bioinformatics Open Source Westin Hotel Web. With the current interest in bio- Conference (BOSC): August 1-2 (9:00- This text-mining meeting has two purpos- ontologies for marking up knowledge con- 17:00) Westin Hotel es. The first is to bring together researchers tent of our resources, together with the BOSC is a two-day conference focusing on developing text tools and relat- interest in E-Science, our community is the development of open source software ed language processing methods to manage well placed to exploit the ideas of the for the life sciences. Keynotes will be deliv- the information explosion in the biomed- Semantic Web. All bio-ontology activity ered by , Winston Hide, and ical field. This part of the meeting will should be able to fit within this theme. the . Leaders from many of the include invited and contributed papers, meeting details and call for abstracts may major open source toolkit projects will with a focus on developing shared infra- be found at img.cs.man.ac.uk/stevens/meet- present progress reports and current appli- structure (tools, corpora, ontologies) and ing02. Additional information may be cations of their toolkits. Additionally, the challenge evaluations, in the style of the requested by emailing conference will include technical talks, a KDD Challenge Cups (KDD Cup 2002). [email protected]. poster session, mini-tutorials, and software The second part of the meeting will be a demonstrations, and Birds of a Feather discussion focusing on the establishment of Workshop on Education in gatherings to discuss specialized interests. a formal SIG for text data mining. Bioinformatics (WEB02): August 8 More information (including a full speaker (9:00-17:00) Westin Hotel list) is available at Special Interest Group for The second annual WEB02 will cover top- www.open-bio.org/bosc2002/. Biological Simulation (SIGSIM02): ics in Bioinformatics Education including August 3 (9:00-17:00) Shaw Conference curriculum development, infrastructure Biopathways: August 1-2 (9:00-17:00) Centre and resource support and strategies for pro- Westin Hotel The construction of computer-made gram initiation and development. There is The fourth BioPathways is organized by models and the conduction of “in silico also a new session on industry needs. In the BioPathways Consortium, an open experiments” may become one of the most addition to short oral and poster presenta- forum to fostering computational important paradigms of biology in this cen- tion sessions, the workshop will attempt to approaches to the modelling, reconstruc- tury. SIGSIM is a group of scientists whose define a curriculum for bioinformatics at tion, analysis, and simulation of biological interests are in simulation technologies, the under-graduate and post-graduate lev- networks. This year’s meeting will include computer modeling of biological processes, els. Abstracts are due June 21, 2002. three plenary sessions, with respective metabolome analysis and systems biology. WEB02 invites faculty, students, staff, focuses on: (1) continuous models for path- This year, SIGSIM will host SIGSIM02: administrators, and officials in government ways representation, (2) pathways recon- Workshop on Computer Modeling of and industry to participate in this discus- struction, and (3) experiment design driven Cellular Processes. Workshop secretariat: sion. surya.bic.nus.edu.sg/web02/ by pathways models (“systems biology” [email protected] approaches). An industry session will fea- ture presentations of applied work in industrial settings. Each session will include

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INTERNATIONAL SOCIETY FOR COMPUTATIONAL BIOLOGY ISMB 2003 DOWN UNDER

ISMB will venture beyond North America and favorable exchange ISMB 2003 Europe for the first time when ISMB 2003 con- rate will help deliver ORGANIZING venes in Brisbane, Australia from June 29 to great value to partici- COMMITTEE July 3, 2003. pants. Gene Myers, Celera Genomics (Co-chair)

The Institute for Molecular Bioscience, and World-class tourist Mark Ragan, Institute for the Advanced Computational Modelling destinations easily Molecular Bioscience (Co-chair)

Centre of the University of Queensland, will accessible from Gene Meyers Kevin Burrage, Advanced serve as local hosts. The venue for the 2003 Brisbane include the ISMB 2003 Co-Chair Computational Modelling conference and tutorials will be the Brisbane Great Barrier Reef, Centre, University of Conference and Exhibition Centre, Australia’s the Gold Coast, Queensland largest purpose-built conference facility, adja- Ayers Rock, and the Antoine Danchin, Pasteur cent to the fabulous South Bank parklands and great Australian out- Research Centre, Hong Kong University a short walk or ferry-ride across the Brisbane back. Sandy beaches, River from the downtown hotel district. The offshore islands, wet Terry Gaasterland, The Organizing Committee, co-chaired by Gene and dry tropical Myers (Program Committee) and Mark Ragan forests, mountains Minoru Kanehisa, Japanese Mark Ragan (Local Committee), is already hard at work to and World Heritage Society for Bioinformatics, Kyoto ISMB 2003 Co-Chair ensure that the conference will meet the high- national parks lie with- University est scientific, technical and organizational stan- in a 1-2 hour drive from downtown. Tim Littlejohn, Biolateral Pty dards and be great fun. Ltd. Delegates and exhibitors may wish to travel on John Mattick, Institute for The organizers are excited by the opportunity to the XIX International Genetics Congress in Molecular Bioscience, University to bring ISMB to the Asia-Pacific region: Melbourne (July 6-12: www.genetic- of Queensland Involving new groups of participants from scongress2003.com) or the Fifth International , European Australia, China, India, Korea, , Congress on Industrial and Applied Bioinformatics Institute Malaysia, New Zealand, Singapore, Taiwan, Mathematics in Sydney (July 7-11: Shoba Ranganathan, Asia- Thailand, and other countries hitherto not www.austms.org.au/iciam2003) immediately Pacific BioNet, National fully represented at ISMB. after ISMB 2003. University of Singapore

Brisbane, the capital of Queensland, is a cos- Monitor the ISMB 2003 website at David Wishart, University of Alberta mopolitan city of 1.6-1.8 million with three www.iscb.org/ismb2003 for updates and major universities and a growing biotechnolo- announcements. gy sector. Delegates may fly direct to Brisbane from all major Australian cities as well as Auckland, Bangkok, Brunei, Hong Kong, Jakarta, Kuala Lumpur, Manila, Osaka, Seoul, Singapore, Taipei and Tokyo. Late June/early July is mid-winter in Brisbane, with sunny warm days (average high 20ºC = 68ºF) and crisp cool nights (average low 10ºC = 50ºF). A

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Summer 2002 Newsletter www.iscb.org ISMB 2002 Job Fair Top Companies! Hot Jobs! Live meetings they need to conduct including inter- Interviews! Great Career Content! views. The ISMB 2002 Job Fair is designed to benefit Company representatives may contact candi- employers looking for top talent as well as students dates directly through the resume postings on and professionals seeking a job. The Job Fair will ISMB’s website (www.ismb02.org/jobfair2.htm) be held on Sunday August 04 from 10:00 – 14:00 or onsite at the Job Fair. at the Shaw Conference Centre. LAST CALL FOR The fee for corporate participation in the Job ISMB attracts the world’s leading industry NOMINATIONS OF Fair is US$500. To sign up for the Job Fair authorities in bioinformatics as well as students 2003 ISCB OFFICERS visit: www.ismb02.org/jobfair.htm AND DIRECTORS and professionals with exceptional talent, inno- The terms of all ISCB offi- vation, and future potential in the field. Candidates cers and several ISCB direc- Prior to the conference, job seekers may post The Job Fair at ISMB 2002 is designed to tors will end in January links to their resume on the ISMB 2002 web- facilitate productive connections between com- 2003, and the Society is site (www.ismb02.org). Potential employers are pany representatives and job seekers. Industry soliciting nominations for encouraged to contact candidates directly to members will be able to meet individuals with those positions.The Society schedule an interview. For resume posting competencies that are applicable to their is particularly interested in instructions, please visit the ISMB 2002 organizations. In addition, rooms will be avail- building board membership resume submissions page able for companies to interview potential can- that represents the geo- (www.ismb02.org/resumesub.htm). graphic diversity and inter- didates. Job seekers will have an unparalleled Please contact employers directly using the job ests of the membership, and opportunity to meet industry members from postings on the ISMB 2002 website seeks nominations from leading companies who will all be in one place Africa,Asia, Europe and at one time. (www.ismb02.org/jobfair2.htm). Monitor the job postings page frequently, as new jobs will South America. New How it all works… Officers and Directors will be added until the commencement of ISMB take office in January of Companies 2002. Please note: It will be possible to contact 2003, and will serve for up Companies who sign up for the Job Fair will corporate representatives onsite at the Job Fair. receive a listing in the conference program to three years. Job seekers should attend the Job Fair recruit- with their company name and contact, one six All ISCB Members are ment event on Sunday, August 4 from 10:00- foot draped table to display company collateral encouraged to put forward 14:00. Candidates—who are encouraged to materials and two chairs. nominees for the President, bring multiple copies of their resumes—may Vice President,Treasurer, Participating companies will also have access to informally meet with company representatives Secretary, and Director the on-line Job Fair to list their job openings and sign up for interviews if appropriate. Job positions. Nominations on the ISMB 2002 website. This gives partici- seekers may also have a chance to receive addi- should be sent by e-mail as pating companies a link on the website that tional information about many leading compa- soon as possible to takes viewers directly to their respective web- nies in the field of bioinformatics. [email protected]. See the site. The ISMB 2002 website receives up to There is no fee for candidates who wish to par- Nominations page of ISCB’s 1000 hits per day and serves as an excellent ticipate in the Job Fair. website (www.iscb.org/nomi- resource to reach a highly skilled pool of nations.shtml) for further potential employees. For additional information, please contact the details regarding eligibility, Job Fair coordinator, Karim Sayani Companies may also book time blocks at the job descriptions, and the ([email protected]). conference for private interview rooms for any nominations process.

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INTERNATIONAL SOCIETY FOR COMPUTATIONAL BIOLOGY ISMB 2002 KEYNOTE SPEAKERS: PIONEERS IN BIOINFORMATICS

ISMB 2002 will continue the tradition of pre- evolutionary origins of prokaryotes and teins and the detailed dynamics of protein- senting keynote speakers investigating biologi- eukaryotes, and this includes wrestling with protein association. He is a professor of cal questions with innovations in computa- the role of lateral gene transfer between sin- and molecular at tional science. gle-celled organisms in and the Columbia University. problems that this lateral transfer raises for Stephen Altschul is a major figure in current methods of phylogenetic recon- John Reinitz, associate professor at State the development of sequence searching struction. Doolittle is a professor of bio- University, New York (SUNY) techniques. He has written papers on the chemistry at Dalhousie University and Stonybrook, applies techniques of informa- appropriate statistical approaches to evalu- director of the Canadian Institute of tion theory to the systematic study of ating sequence alignments. Altschul devel- Evolutionary Biology. embryonic development in Drosophila oped the immensely powerful and flexible melanogaster. His theoretical treatments of sequence searching program BLAST as well Terry Gaasterland is a leading figure in this complex phenomenon are based on as variations on the central idea of BLAST the field of automated genome annotation. experimental determination of the chang- that have improved the sensitivity of the While at the Argonne National Laboratory ing concentrations of maternally-derived searching process: PHI-BLAST and PSI- and the University of Chicago she devel- signaling gene products as the hierarchy of BLAST. He is currently a Senior oped the MAGPIE annotation system. determination develops in the syncytial Investigator with the Computational Since moving to the Rockefeller University, blastoderm. His efforts have transformed Biology Branch of the National Center for where she is currently an assistant profes- the descriptive analyses of the patterns of Biotechnology Information (NCBI). sor, she has initiated development of sever- individual gene expression into a well- al other annotation tools. These include defined, predictive model of information has been one of the HERON, TANGO, EGRET and SAND- flow during the development of the funda- pre eminent researchers in the study of PIPER, all based on logic-based queries for mental body plan. throughout his manipulating semantic information. She is career. With the advent of the Drosophila applying these tools to microarray data, Isidore Rigoutsos is the manager of the genome sequencing initiative, he developed phylogenetic inference, and structural biol- Bioinformatics and Pattern Discovery FLYBASE, a powerful annotation platform ogy projects. group at IBM’s Computational Biology that integrated new genome sequence data Center. He developed the Teiresias algo- with the corpus of knowledge of genetic, Barry Honig has developed many com- rithm, a generalized method for unsuper- developmental and physiological mecha- putational tools for studying and modeling vised pattern discovery. He and his collabo- nisms amassed over the last century. Most protein three dimensional structure. His rators have implemented this algorithm for recently he has been a pivotal player in the extensive theoretical treatments of molecu- a number of biological pattern identifica- development of the Gene Ontology proj- lar energetics and dynamics are providing tion problems and categorization problem ect. He is currently a professor in the new insights into the mechanisms of pro- covering most of the questions that are cur- Department of Genetics at Cambridge tein structure, protein-protein interactions, rent in computational biology. This soft- University and a Senior Researcher at the and protein-membrane interactions. As ware initiative is a major part of the IBM European Bioinformatics Institute (EBI). high-throughput structure prediction BlueGene project in computational methods are being developed, Honig’s biology. Ford Doolittle has studied evolution work is at the leading edge of method from a molecular perspective for most of development and investigating mechanisms his scientific career. He has been studying of membrane targeting by peripheral pro-

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Summer 2002 Newsletter www.iscb.org INVITED EDITORIAL

I have the honor of being the first female Vice standards, by expanding our community with President of the ISCB as well as representing the active recruitment of young talented scien- my European colleagues on the Society’s tists, and by providing them with educational Executive Committee. As such, I hope to suc- opportunities. ceed as efficiently and brilliantly as my prede- cessors in keeping the Society vital and for- ISMB, the Society’s annual meeting, represents ward-looking. the most effective tool for pursuing these goals, through the rigorous selection process for sci- I first became interested in computational biol- entific contributions: the organization of tuto- ogy nearly twenty years ago, I took a post-doc- rials, the visibility of the meeting, and the toral research fellowship at the University of diversity of scientific interests. The success of California, San Francisco’s (UCSF) the meeting continues to represent a precious Department of Biochemistry and Biophysics, and unique resource for the development of Anna Tramontano, ISCB Vice President where I discovered molecular graphics. While bioinformatics and computational biology at UCSF, my collaboration with Henry worldwide. Dayringer and Robert Fletterick, yielded the first version of a popular molecular graphics I am extremely optimistic about the role package that is still widely used today. Later, I regional groups can play in the ISCB. As an joined Arthur Lesk’s group in the international society, we have the opportunity Biocomputing Programme at the European to face many situations with different needs Laboratory (EMBL) in and expectations. We need to muster the cre- Heidelberg. The Programme—coordinated by ativity, wisdom, and cooperation of everyone —set in motion the field of com- in the society to ensure we remain engaged, putational biology in Europe. Most active both geographically and scientifically. We research groups in Europe today—as well as a must communicate and build strong bonds few in other parts of the world—can be traced with local groups and ask for their guidance back to that period and to the many fruitful during these exciting times. collaborations computational biologists initiat- In the few months I have served as Vice ed, over a beer, in the EMBL canteen! President, I have discussed these issues with a I suppose I was witness to the adolescence of a very responsive and attentive board of direc- science leaving infancy. Certainly in silico biol- tors. I intend to continue to support these ogy is a mature science now experiencing causes and hope that the members of the immense popularity. Sudden popularity in the Society will continue to help me achieve my movie business, as well as in science, carries goals. risks. Growing interest in bioinformatics and computational biology may lead to an erosion of the terms caused by the temptation to “jump on the band wagon” for the sake of the resources that are becoming available.

In my view, the Society has a duty to play an active role in minimizing the negative effects of this new celebrity by setting rigorous scientific

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INTERNATIONAL SOCIETY FOR COMPUTATIONAL BIOLOGY ISCB STATEMENT ON BIOINFORMATICS SOFTWARE AVAILABILITY

I. INTRODUCTION one of those definitions as a minimal require- b. For Commercial Use: The software will be Conditions of bioinformatics software ment of software availability that funding available in binary form, on an “as is” basis availability are extremely important to the agencies should require. to commercial institutions, possibly for a fee, field of bioinformatics. The ISCB, a profes- for non-exclusive use, without the right of the III. ISCB LEVELS OF SOFTWARE sional society of 1300 bioinformatics scien- licensee to redistribute the software. AVAILABILITY tists, has discerned significant confusion in ISCB Level 1 Availability (“No fee”): The International Society for recent months regarding the topic of soft- The software will be available free of charge Computational Biology (ISCB) provides ware availability, and is disseminating this to all institutions, in binary form, on an “as the following definitions of software avail- statement to clarify several issues regarding is basis”, for non-exclusive use, without the ability. It is ISCB’s intent that these defini- software availability, and to make recom- right of the licensee to further redistribute tions be a standard reference. It is recom- mendations on software availability policies the software. mended that all software availability be for government agencies that fund bioin- defined in these terms (or specific stated formatics research. ISCB Level 2 Availability (“No fee, variations thereof) and stated in all publica- source code for research use”): II. RECOMMENDATIONS tions, grant applications, and other docu- Same as ISCB Level 1; in addition, source 1. The term “open source” has taken on many ments that describe software availability. code is available for research use to educa- different meanings. This term creates confu- tional institutions, non-profit research ISCB recommends that government fund- sion in discussions of software availability; institutes, government research laborato- therefore the term should be carefully quali- ing agencies that support bioinformatics ries, and individuals, without the right to fied to indicate which variation of the open- research, require a minimum of ISCB Level redistribute the source code. source model is intended. 0 Availability. ISCB Level 3 Availability (“No fee, 2. Government agencies that fund bioinformat- The levels of availability listed here are not ics research should NOT REQUIRE that source code to all”): meant to be exhaustive. Researchers may software produced with government research Same as ISCB Level 1; in addition, source want to define variations to these levels, funds must be distributed under open-source code is available to commercial institutions. but ISCB strongly suggests that at least license (particularly given the ambiguity in the meaning of that term). Because of the Level 0f Availability be maintained. ISCB Level 4 Availability (“No fee, complexity inherent in software, no single dis- unlimited redistribution, with For all levels of availability, the licensee tribution model is appropriate for all research source code”): must clearly acknowledge the contributions projects. Government agencies should require The software will be available free of charge of the author(s) of the original software in clear statements of software availability in to all institutions and individuals, in binary all redistributions. grant proposals. and source-code forms, on an “as is” basis, 3. As reviewers of bioinformatics grant applica- ISCB Level 0 Availability: for non-exclusive use. The licensee may tions, ISCB scientists have noted that these a. For Research Use: The software will be avail- redistribute and/or resell the original soft- applications often contain confusing or able free of charge, in binary form, on an “as ware including the source code, and may unclear statements regarding the availability is” basis for research purposes to educational redistribute and/or resell any modifications of software that will be developed under gov- institutions, non-profit research institutes, or derivative works created by the licensee. ernment grant funds. This statement contains government research laboratories, and indi- The licensee must clearly acknowledge the several definitions of software availability viduals, for non-exclusive use, without the contributions of the author(s) of the origi- that ISCB recommends for use in bioinfor- right of the licensee to further redistribute the nal software in all redistributions. matics grant applications. ISCB recommends software.

This statement does not constitute, and should not be construed as, giving legal advice. Nothing in this statement is intended to constitute the giving of legal advice.The reader should consult with counsel before pursuing a course of action in reliance on information contained in this statement.

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Summer 2002 Newsletter www.iscb.org AFFILIATED REGIONAL GROUPS

Just as ISCB’s global membership has • INBIOS-Bioinformatics Society of India Board from Affiliated Regional Groups increased, new relationships with affiliated www.inbios.org through the Society’s regional POCs regional groups have formed and old part- • Italian Cooperation Group in • Eligibility for support of regional activi- nerships have strengthened. ISCB has start- Bioinformatics cbm.bio.uniroma2.it/ ties: Travel funds for a recognized scien- ed an Affiliated Regional Group Program to biocomp tist in the field to lecture at a regional promote bioinformatics as a scientific disci- • Japanese Society for Bioinformatics meeting or workshop; travel fellowships pline, and increase public and governmental www.jsbi.org for scientists from the region to travel to recognition of its importance. ISMB • Rocky Mountain Regional Center for ISCB is pleased to announce the following Computational Biology members of the Affiliated Regional Group www.cudenver.edu/ccb Program (www.iscb.org/affiliates.shtml): • Israeli Society for Bioinformatics and • Asia Pacific Bioinformatics Network Computational Biology (forming) www.apbionet.org ISCB Affiliated Regional Group Program The ISCB—through its Affiliated Regional • Boston Area Molecular Biology participants may benefit from the following: Group Program—is hopeful this effort will Computer Types xanadu.mgh. • Cross-visibility within one another’s web strengthen the bioinformatics community harvard.edu/bambct/bambct-intro.html pages, conferences, journals, and bulletins by providing a locality for mutual support • Bay Area Bioinformatics www.bayare- • Affiliated Regional Groups may request to advance common interests of bioinfor- abioinformatics.org access to facilities at ISMB—ISCB’s offi- maticians at large. Members of regional • Bioinformatics-India www.bioinformat- cial conference—for regional meetings bioinformatics and computational biology ics-india.com groups who consider affiliation with ISCB • Appointment of an ISCB Board member • Biological Research Information Center as affiliate point of contact (POC) to con- to be potentially beneficial for their organi- of Korea bric.postech.ac.kr/bricenglish/ sider regional matters relevant to ISCB zations, are encouraged to contact index.html [email protected] for further information. • Solicitation for nominations to ISCB’s

ISCB STAFF TEAM (introduced in newsletter 5.1), the ISCB The rest of the ISCB staff serves the The ISCB has recently undergone major is supported by a second full-time majority of the time for different depart- administrative and behind-the-scenes employee, Stephanie Hagstrom.An ments within the San Diego changes, such as the update of its website award-winning meeting planner, Hagstrom Supercomputer Center (SDSC) and the and overhaul of its membership database. works for ISCB as the ISMB Conference National Partnership for Advanced The Society’s newsletter has been Liaison, which includes overseeing nearly Computational Infrastructure (NPACI). revamped and an official history of the every aspect of organization and logistics Kim Baldridge, program director for Society initiated as well as significant for the Society’s annual conference. SDSC’s Integrative Computational planning accomplished for the next few When not working, she spends time with Sciences program, oversees the ISCB years of the Society’s official conference, her family, is active in Meeting staff.Additionally, Baldridge is deputy ISMB.Those efforts are the products of Professionals International, and serves on director of the NIH NCRR National the ISCB staff (group photo p2), under the the board of directors for Mama’s Biomedical Computation Resource guidance of ISCB President Phil Bourne. Kitchen, a San Diego organization that (NBCR) at SDSC and founded the Maria Apart from the Society’s full-time admin- delivers food to individuals and families Goeppert-Mayer Annual Interdisciplinary istrative officer, BJ Morrison McKay living with HIV/Aids. Symposium. (continued)

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INTERNATIONAL SOCIETY FOR COMPUTATIONAL BIOLOGY STUDENT TRAVEL FELLOWSHIPS

This year, the ISCB provided travel awards Molecular Biology (RECOMB), held in based on geographic origin, field of study, for graduate students and postdoctoral Washington DC. Each was awarded a $500 and paper or poster presentation, though researchers to attend the 2002 International travel fellowship to help cover the costs of presenting a poster or paper was not a Conference on Research in Computational attending the conference. The selection was requirement for selection.

The winners included: Annette Höglund, a graduate student at Saarland University, Germany; M. Madan Babu, a graduate stu- dent at the , UK; Hilary Booth, a postdoctoral at the Australian National University; Dana Pe’er, a graduate student at Hebrew University, Israel; Tomas Vinar, a graduate student at the University of Waterloo, Canada; Sven Rahmann, a graduate student at the Max- Planck-Institut für Molekulare Genetik, Germany; Guang Song, a graduate student in the Department at Texas A&M University, US; Claudia Rangel at Claremont Graduate University, US; Aik Choon Tan at the University of Glasgow, Scotland; Yujin Hoshida, a post- graduate student at the University of ISCB Travel Fellowship Recipients and Board Members (clockwise from far left):Annette Höglund, Madan Babu Mohan, Hilary Booth, Dana Pe’er,Tomas Vinar, Sven Rahmann, Guang Song ,Ydo Wexler, Barbara Tokyo, Japan; and Ydo Wexler a graduate Bryant, David Rocke, Phil Bourne (not pictured: Aik Choon Tan and Yujin Hoshida) student at the Technion, Israel.

In addition to writing and editing articles hiking and running with her husband and Biosciences and Integrative and press materials for the ISCB, Cassie their Australian Shepherd. Computational Sciences programs, and Ferguson works on SDSC’s biweekly Group leader of the web and database the NBCR. He also curates the CMS newsletter, Online, and the NPACI quar- group in the High End Computing Molecular Biology Resource and tinkers terly magazine, EnVision.A graduate of the Program at SDSC, Josh Polterock, ISCB’s in bioinformatics when time permits. University of California, Santa Cruz pro- webmaster, provides support for about When not in front of a computer, Smith gram in Science Communication, she 200 web applications, and database serv- collects power tools and has employed prefers to spend her extra time in the ices to projects at SDSC and NPACI. them on projects from home construc- outdoors with her family. When not tending to web servers and tion to crafting custom furniture. ISCB graphic designer and newsletter services, he spends time with his wife, Tracy Zhao who works as the ISCB data- editor, Jennifer Matthews, produces web Christine, and three kids, Hannah 7, Sam base administrator, created a new data- and print materials for several depart- 6, and Sadie 2. base for the membership and implement- ments within SDSC as well as for the ISCB finance manager, Chris Smith, is ed a new online payment for the ISCB. Scripps Institute of Oceanography’s program manager for SDSC’S Integrative She also works as a programmer analyst ROADNet project. Matthews also enjoys for SDSC.

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Summer 2002 Newsletter www.iscb.org EVENTS AND OPPORTUNITIES OF INTEREST

DIMACS Special Focus on Computational complex biological interactions, which are criti- papers on their most important research contri- Molecular Biology cal to the accurate annotation of genomic butions in the recent period. DATE: September 2000-August 2003 sequences, the study of the interplay between UPCOMING EVENT: Protein Domains: genes and proteins, and the study of the genetic CALL FOR SUBMISSIONS: Discrete Identification, Classification and Evolution variability of species. Dynamics in and Society (DDNS) Dates: February 27-28, 2003; DIMACS Center, Special Issue: Complex Multi-Agent Rutgers, Piscataway, New Jersey, USA NETTAB 2002 Second International Interaction Dynamics URL: dimacs.rutgers.edu/Workshops/ Workshop on Agents in Bioinformatics DEADLINE August 31, 2002 index-compmolecbiol.html DATE: July 12-14, 2002 URL: www.tandf.co.uk/journals/titles/ LOCATION: Bologna, 10260226.html SHORT COURSE: Bioinformatics: Methods URLs: www.nettab.org, ABOUT: DDNS’s main field of interest is the and Techniques www.nettab.org/2002/progr.html use of nonlinear difference equations to model DATE: June 18-20, 2002 ABOUT: This workshop aims to bring together complex phenomena in natural and social sys- LOCATION: Stanford, Palo Alto, CA, USA researchers working toward the vision of a tems. However, the rise in computer processing URL: http://scpd.stanford.edu/scpd/courses/ genome analysis and annotation using agents- power, and the development of powerful parallel proEd/bioinf/default.asp?bioinformatics_iscb based systems. NETTAB2002 aims to strength- processing hardware and software, has made it ABOUT: An introduction to fundamental prob- en the relationships within the bioinformatics possible to model many complex systems as the lems in genomics and bioinformatics. Topics community, to activate cooperation between result of the interactions of discrete agents. This include DNA and protein sequence and struc- bioinformatics and computer science communi- special issue of DDNS will focus exclusively ture analysis, structure prediction and the ties, to collect the latest ideas, achievements and upon this approach to system modeling. Papers impact of new technologies such as mRNA proposals in the application of agents and multi- will be considered on any and all topics, so long expression arrays and techniques. agent systems to the bioinformatics area. as the paper meets the parameters of using inter- CONTACT: Jody Gladstein, 650-723-9041 active multiple agent systems to generate or ([email protected]) The Third International Conference on explain complex systems. Bioinformatics of Genome Regulation Bioinformatics and Structure (BGRS2002) DATE: June 19-21, 2002 SHORT COURSE: An Introduction to DATE: July 14-20, 2002 LOCATION: Boston, MA, USA Bioinformatics: A Practical Approach LOCATION: Novosibirsk, RUSSIA URL: www.LifeScienceSolutions.com DATE: September 2-3, 2002 URL: www.bionet.nsc.ru/meeting/ ABOUT: This information-intensive conference LOCATION: University of Warwick, bgrs2002/index_local.html will bring together the industry’s most forward- Coventry, UK ABOUT: BGRS2002 will provide a forum for thinking computational biologists to examine URL: www.bio.warwick.ac.uk/shortcourses the accumulation, analysis, and recognition of diverse bioinformatics strategies and applica- ABOUT: A course for those wishing to gain a genomic regulatory sequences. Experimental tions. Key components of this event include practical understanding of the applications of biologists are also encouraged to attend— open-source industry collaboration and integra- bioinformatics BGRS2002 aims to be a stimulating event to tion, computational proteomics, post-genomic CONTACT: Dr. Charlotte Moonan, 024-7652- facilitate an application of computational biolo- bioinformatics and drug discovery. Focused pre- 3540 ([email protected]) gy to experimental research. conference tutorials will offer hands-on experi- ence with leading bioinformatics tools. SSGRR-2002: Infrastructure for e-Business, e- WABI 2002: 2nd Workshop on CONTACT: Ann Pendleton, 312.894.6418 (con- Education, e-Science, and e-Medicine in BioInformatics [email protected]) DATE: July 29-August 4, 2002 DATE: September: 16-21, 2002 LOCATION: L’Aquila near , ITALY LOCATION: Faculty of Engineering, University Bioinformatics and Genomics: Methods, URLs: www.ssgrr.it/en/ssgrr2002s/index.htm of Rome “La Sapienza,” ITALY Data, and Predictions ABOUT: SSGRR decided to organize twice a URL: www.dis.uniroma1.it/%7Ealgo02/wabi02 DATE: June 24-28, 2002 year an international symposium in the general ABOUT: LOCATION: Laboratory for Information, WABI2002 will cover research in algo- domain of Infrastructure for e-Business, e- SINGAPORE rithmic work in bioinformatics and computa- Education, e-Science, and e-Medicine (in the tional biology. The emphasis is on discrete algo- URL: sdmc.krdl.org.sg/cimm/BGMDP02 widest sense: computer science and engineering, ABOUT: The program on Post-Genome rithms that address important problems in communications, and business administration), Knowledge Discovery will focus on the compu- molecular biology, genomics and genetics that with the goal of getting together the leading tational and statistical analysis of sequence and world experts in the field, to present invited genetic data and the mathematical modeling of 14

INTERNATIONAL SOCIETY FOR COMPUTATIONAL BIOLOGY are founded on sound models, computationally Invitation to the 3rd International ADDITIONAL ITEMS efficient, and have been implemented and tested Conference on Systems Biology: The European Drive for Post-Genomic in simulations and on real datasets. Logic of Life Research DATE: December 13-15, 2002 In a drive to gear up research on genomics the LOCATION: Second Virtual Conference on Genomics Karolinska Institutet, Stockholm, European Commission has awarded $39.4 mil- and Bioinformatics Sharing Knowledge lion to three large research projects. The fund- URL: with the World www.icsb2002.org ing is a prelude to the $2.2 billion earmarked for DATE: September 24-26, 2002 ABOUT: ICSB 2002 will feature experimental, “genomics research for human health” in the LOCATION: Fargo, North Dakota, USA computational and theoretical advances in the next community research programme to be URL: www.ndsu.nodak.edu/virtual- rapidly advancing fields of gene expression launched later this year. The projects on the genomics/upcom2.htm acquisition technologies, gene expression data genetics of twins, mouse genomics and structur- ABOUT: This conference will provide an envi- analysis, functional analysis of biological control al proteomics are demonstrating the new way in ronment to discuss information related to post- systems, proteinomics, modeling and analysis of which the Commission will fund research in the genomic era innovations. Genomic research has kinetic networks, metabolomics, signal trans- future: asking scientists from industry and aca- led to an explosive rate of data accumulation duction, morphogenesis, and much more. demia to compose top teams from across and a shift in the way biological research is con- Europe to conduct research at the cutting edge ducted. This conference will feature high profile First Asia-Pacific Bioinformatics of science in a selected number of fields and giv- researchers and educators developing new appli- Conference Within Australia ing them sufficient means to achieve critical cations in genomics and bioinformatics. DATE: February 4-7, 2003 mass and world-class excellence. This effort is LOCATION: Adelaide, AUSTRALIA part of the European Commission’s commit- European Conference on Computational URL: www.fit.qut.edu.au/~chenp/APBC2003 ment to invest more and better in the creation Biology 2002 (ECCB 2002) ABOUT: Database management, artificial intel- of knowledge and to build a coherent European DATE: October 6-9 2002 ligence, data mining, and knowledge representa- Area for Research and Innovation. LOCATION: Saarbrücken, GERMANY tion can provide key solutions to the challenges URL: www.eccb2002.de presented by biological data. Opportunities are American Heart Association (AHA) ABOUT: The ECCB conference provides an emerging to integrate molecular biology compo- The AHA supports research activities broadly opportunity to present cutting edge research in nents of bioinformatics with computational, related to cardiovascular function and disease, computational biology. This multi-disciplinary physiological, morphological, taxonomic, and stroke, as well as basic science, clinical, bioengi- conference bridges computer science, molecular ecological components. Addressing this chal- neering/biotechnology and public health prob- biology, biochemistry, pharmaceutics, and med- lenge will facilitate the way life science research- lems. National Research Programs are offered bi- icine by bringing together involved scientists es retrieve, analyze and visualize data and rela- annually. Application deadlines: July 15, 2002; from all over the world. tionships in a collaborative work environment. January 13, 2003 Information and forms are CONTACT: CONTACT: [email protected] Dr. Phoebe Chen, +61-7-3864-1945; available at www.americanheart.org/research. +61-7-3864-1969 (fax) ([email protected]) BioDigital 2002: International Trade Israeli Society for Bioinformatics and Fair and Conference for Biotechnology, CALL FOR SUBMISSIONS: International Computational Biology Bioinformatics and Microarrays Journal of Cooperative Information The newly formed Israeli Society for DATE: October 9-11, 2002 Systems Bioinformatics and Computational Biology LOCATION: Messe Freiburg in Freiburg/ URL: www.worldscinet.com/ijcis/mkt/ (ISBCB) has nominated their first president, Breisgau, GERMANY guidelines.shtml Professor (Department of URL: ABOUT: www.biodigital.de This special issue’s focus is Data Molecular Genetics and Biotechnology, The ABOUT: Systems Biology, Protein Microarray, Management and Modeling Support in Hebrew University), to a two year term. DNA Chips, Bioinformatics. The connection of Bioinformatics. Papers describing state-of-the Founded at the 2002 Israeli Bioinformatics trade fair and top-class conference of the research including, but not limited to, the fol- Annual Meeting, ISBCB is currently in the BioDigital 2002 offers an interesting panel for lowing areas are solicited: Database integration process of officially registering as a society with science and business decision makers in and interoperability; Information Modeling, Israeli authorities. Microarray technology and Bioinformatics. metadata and data sharing; Multidatabase CONTACT: +44-0-20-7017-5069; indexing and multidatabase queries; Data To recommend a conference for inclusion in +44-0-20-7017-4822 (fax) semantic and control; Ontology design; the ISCB Newsletter, please write to Knowledge discovery and datamining; [email protected]. Algorithms for large scale and distributed bio- logical databases

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Summer 2002 Newsletter www.iscb.org How are We Doing? Please email ISCB staff at [email protected] with any comments, questions, or concerns regarding the website (www.iscb.org), this newsletter, or any other ISCB effort.The ISCB staff aims to meet the needs of ISCB’s membership—member advice goes a long way toward helping the staff meet their objectives.

ISCB acknowedges the support from the National Biomedical Computation Resource, at the San Diego Supercomputer Center, at the University of California, San Diego, which provides the computational infrastructure for the ISCB web resource and underlying databases.

www.iscb.org

INTERNATIONAL SOCIETY FOR COMPUTATIONAL BIOLOGY