CURRICULUM VITAE Gregory J. Cole
Present Position: Professor Department of Biological and Biomedical Sciences Julius L. Chambers Biomedical/Biotechnology Research Institute North Carolina Central University 700 George Street Durham, NC 27707 Voice: 919-530-6034 Fax: 919-530-7760 e-mail: [email protected] Webpage: https://sites.google.com/site/colelabpage
Education:
1973-1976 B.A., Biology, State University of New York, Plattsburgh, NY
1978-1982 Ph.D., Biological Science (Program in Neuroscience), Florida State University, Tallahassee, Florida
Post-doctoral Experience:
1982-1985 Department of Biological Chemistry, Washington University School of Medicine, St. Louis, MO
Professional Experience:
1985-1986 Instructor, Department of Biological Chemistry, Washington University School of Medicine, St. Louis, MO
1986-1987 Research Assistant Professor, Department of Biochemistry, University of Miami School of Medicine, Miami, FL
1987-1991 Assistant Professor, Department of Anatomy and Cell Biology, Medical University of South Carolina, Charleston, SC
1 1991-1993 Associate Professor, Department of Anatomy and Cell Biology, Medical University of South Carolina, Charleston, SC
1993-1998 Associate Professor, Neurobiotechnology Center, The Ohio State University, Columbus, OH
1993-1998 Associate Professor, Department of Cell Biology, Neurobiology, & Anatomy, The Ohio State University, Columbus, OH
1998-1999 Professor, Department of Cell Biology, Neurobiology, & Anatomy, The Ohio State University, Columbus, OH
1998-2000 Professor, Neurobiotechnology Center, The Ohio State University, Columbus, OH
1999-2000 Professor, Department of Neuroscience, The Ohio State University, Columbus, OH
1999-2000 Chair, The Ohio State University Neuroscience Graduate Studies Program
2000-2002 Professor and Department Head, Department of Anatomy, Physiological Sciences, and Radiology, College of Veterinary Medicine, North Carolina State University
2001-2004 Director, Comparative Biomedical Sciences Graduate Program, College of Veterinary Medicine, North Carolina State University
2002-2004 Department Head, Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University
2002-2005 Professor, Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University
2005-2007 Senior Research Scientist, Julius L Chambers Biomedical/Biotechnology Research Institute, North Carolina Central University
2005-2007 Director, Developmental Biology Program, Julius L Chambers Biomedical/Biotechnology Research Institute, North Carolina Central University
2006-2007 Interim Director, Neuroscience Research Program, Julius L Chambers Biomedical/Biotechnology Research Institute, North Carolina Central University
2007- Director, Neuroscience Research Program, Julius L Chambers Biomedical/Biotechnology Research Institute, North Carolina Central University
2 2007-2015 Professor, Department of Biology, North Carolina Central University
2010-2015 Chair, Department of Biology, North Carolina Central University
2010- Adjunct Professor, Integrated Toxicology Program, Duke University
2015- Professor, Department of Biological and Biomedical Sciences, North Carolina Central University
2015-2019 Chair, Department of Biological and Biomedical Sciences, North Carolina Central University
2020- Director, Integrated Biosciences PhD program, North Carolina Central University
Honors and Fellowships:
1978-1979 NIMH Predoctoral Fellowship
1979-1982 Florida State University Psychobiology Predoctoral Traineeship
1984-1986 NIH National Research Service Award (F32)
1989 Rushton Lecturer, Program in Neuroscience, Florida State University
1998 Named as “Top Ten” teacher in 1st year medical curriculum, The Ohio State University
2017 Florida State University Program in Neuroscience 2017-2018 Distinguished Graduate Award
Past and Current Research Grant Support:
1/87-12/91 NIH R29 EY07130, P.I., 50% effort, “Neural Retina Differentiation”, $476,000 total costs
8/89-7/92 NIH R01 NS26087, P.I., 25% effort, “Characterization of HSPGs in Neural Development”, $327,930 total costs
7/92-6/96 NIH R01 NS29934, P.I., 40% effort, “Molecular Analysis of CNS Barrier Structures”, $871,597 total costs
3 7/94-6/95 NIH R01 NS29934-03S1, P.I., “Molecular Analysis of CNS Barrier Structures”, $18,711 total costs
5/95-4/99 NIH R01 NS33981 (01-04), P.I., 25% effort, “Heparan Sulfate Proteoglycans in Neural Development”, $827,348 total costs
4/99-3/03 NSF, IBN 9817201, P.I., 20% effort, “Agrin Interactions with Extracellular Matrix”, $247,246 total costs.
9/99-8/04 NIH R01 NS33981 (05-08), P.I., 25% effort, “Heparan Sulfate Proteoglycans in Neural Development”, $1,135,980 total costs
9/01-8/02 NIH R01 NS33981-06S1, P.I., “Heparan Sulfate Proteoglycans in Neural Development”, $11,290 total costs
9/01-8/02 NIH R01 NS33981-06S2, P.I., “Heparan Sulfate Proteoglycans in Neural Development”, $37,577 total costs
9/02-8/03 NIH R01 NS33981-07S1, P.I., “Heparan Sulfate Proteoglycans in Neural Development”, $65,524 total costs
4/03-3/04 North Carolina Biotechnology Center IDG 1009, P.I., 0% effort, “Confocal Microscope Imaging System”, $151,626 total costs.
7/05-3/10 NIH R01 NS33981 (09-12), P.I., 65% effort, “Heparan Sulfate Proteoglycans in Aging and Development”, $1,256,745 total costs.
7/09-3/10 NIH R01 NS33981-12S1, P.I., “Heparan Sulfate Proteoglycans in Aging and Development”, $46,896 total costs.
6/06-11/08 North Carolina Biotechnology Center, P.I., 10% effort, “Generation of a zebrafish model for Alzheimer’s disease”, $237,871 total costs
3/07-5/08 North Carolina Biotechnology Center, P.I., 0% effort, Educational Enhancement Grant, “Enhancement of biotechnology education and training of NCCU faculty and students”, $12,000 total costs.
6/08-8/10 P20 MD000175 (06-10), F. Calhoun P.I., (P.I. of Pilot Project, 5% effort), “Fetal alcohol syndrome model in zebrafish”, $200,000 total direct cost
8/10-7/15 NIH U54 AA019765 (01-05), P.I., 30% effort, “Mechanisms of Alcohol Pathology: A Collaborative Partnership Between NCCU & UNC”, $4,294,310 total costs.
8/15-7/21 NIH U54 AA019765 (06-10), P.I., 20% effort, “Mechanisms of Alcohol Pathology: A Collaborative Partnership Between NCCU & UNC”, $4,722,071 total costs.
4 3/17-7/19 NIH U54 AA019765-07S1, P.I., “Mechanisms of Alcohol Pathology: A Collaborative Partnership Between NCCU & UNC”, $24,687 total costs. 11/17-7/18 NIH U54 AA019765-08S1, P.I., “Mechanisms of Alcohol Pathology: A Collaborative Partnership Between NCCU & UNC”, $45,542 total costs.
9/18/-8/21 NIH R21 AA025400, P.I., “Gene-ethanol interactions in a zebrafish multi-binge FASD model”, $405,079 total costs.
Editorial Consultant:
Brain Research The Cerebellum The Journal of Cell Biology Journal of Neurobiology Journal of Neuroscience Journal of Cell Science Experimental Cell Research Developmental Dynamics Investigative Ophthalmology and Visual Science Developmental Brain Research PLoS One Gene Zebrafish Neurotoxicology and Teratology Birth Defects Research Part A: Clinical and Molecular Teratology Genes, Brain and Behavior Developmental Neuroscience Alcoholism Clinical and Experimental Research Alcohol Addiction Biology Chemico-Biological Interactions
5 Professional Service:
1987 Ad hoc member, NINDS Neurology B2 study section
1989- NSF external reviewer
1989-1990 Ad hoc member, NINDS Neurology B2 study section
1990-1994 Regular member, NINDS Neurology B2 study section
1995 Reviewer, NHLBI Site visit
1998 Ad hoc member, NINDS BDCN-2 Special Emphasis Panel
2000 Ad hoc member, NINDS BDCN-2 study section
2003 Member, NIBIB Special Emphasis Panel, “Research Opportunities in Tissue Engineering”
2004-2009 Member of Advisory Committee, NIH Research Infrastructure at Minority Institutions (RIMI) Grant, Alabama State University, Montgomery, AL
2005 Ad hoc member, NINDS SYN study section
2007 Member, NIEHS Special Emphasis Panel, “Disease Investigation through Specialized Clinically Oriented Ventures in Environmental Research (DISCOVER)”
2007 Member, NIH MIST Special Emphasis Panel, Cell Biology
2008 Ad hoc grant reviewer, Jeffress Memorial Trust Proposal, state of Virginia
2009 Ad hoc grant reviewer, The Wellcome Trust, London, UK
2009 Member, NIH ZRG CB-D Special Emphasis Panel, Intercellular Interactions
2010 Member, NIH Special Emphasis panel, NIH Director’s Pathfinder Award
2012 Chair, External Review Committee, Department of Biology external review, NC A&T University
2013 Member, Special Emphasis Panel, NIEHS R13 Scientific Meeting Committee
2013-2015 Member, Special Emphasis Panel, NIAAA AA-4 Meeting
2017 Ad hoc grant reviewer, Israel Science Foundation
6
University Committee Membership:
Medical University of South Carolina:
1987-1991 MSTP Steering Committee
1989-1992 Anatomy and Cell Biology Graduate Coordinator
1989-1992 Anatomy & Cell Biology representative to Graduate Council
1989-1992 Anatomy and Cell Biology Curriculum Committee
1990-1991 Chair, MSTP Student Progress Committee
1990-1992 Executive Committee, Molecular and Cell Biology Program
Ohio State University:
1994 Gene Therapy Task Force, College of Medicine
1994-1995 Chair, Biotechnology Center Nucleic Acid Facility Advisory Committee
1994-2000 Neuroscience Graduate Program Studies Committee
1994-1998 Cell Biology, Neurobiology and Anatomy Graduate Studies Committee
1994-1996 Ohio State Biochemistry Program (OSBP) Graduate Studies Committee
1994-1996 Chair, Recruitment Subcommittee, OSBP
1994-1998 University Radiation Safety Committee
1996 Chair, Molecular Neurobiology Search Committee, Neurobiotechnology Center
1997 Structural Biology Search Committee, Neurobiotechnology Center
1998 Molecular Neurobiology Search Committee, Molecular Life Sciences Initiative
1998-1999 Executive Committee, Cell Biology, Neurobiology & Anatomy
1998-2000 Appointment, Promotion and Tenure Committee, College of Medicine
1999 Curriculum Committee, Integrated Biomedical Sciences Graduate Program
7
North Carolina State University:
2000-2004 Faculty Committee on Veterinary Faculty Practice Plan
2001 Chair, MPP Department Head Search Committee, College of Veterinary Medicine
2002 Graduate Program Review Task Force
North Carolina Central University:
2007 Chair, North Carolina Research Campus Faculty Search Committee
2008-2010 IACUC
2008-2010 Faculty Teaching Evaluation Committee, Department of Biology
2009-2010 College of Science and Technology Interdisciplinary Research Committee
2010 College of Science and Technology Dean Search Committee
2014, 2016 BBRI Director Search Committee
2014-2015 Academic Affairs Strategic Planning Committee
2015 Chair, Department of Pharmaceutical Sciences Chair Search Committee
2015 Chair, RPT Committee, Department of Pharmaceutical Sciences
2016-2018 NSF Faculty Workload and Rewards System, NCCU participant
2017 Science and Mathematics faculty Search Committee, School of Education
2019- Faculty Evaluation Committee (Co-Chair)
2020- Chair, BBS Graduate Studies Committee
8 Teaching Duties:
Medical University of South Carolina:
1987-1993 Medical Neuroscience
1987-1993 Advanced Cell Biology
1988 Developed and directed Developmental Neurobiology graduate course
1989-1991 Medical Cell Biology Tutorial sessions
1992-1993 Neuroanatomy laboratory, Medical Neuroscience
Ohio State University:
1993-2000 Neuroscience 723, Cellular and Molecular Neurobiology
1993-2000 Neuroscience 800, Molecular Neurobiology
1994-2000 Course Director, Neuroscience 723, Cellular and Molecular Neurobiology
1995-1999 CBNA 804, Advanced Cell Biology
1995-1998 Med I (Medical School)- Cell Systems Module
1996-2000 Med I (Medical School)- Neuroscience Module 1997 Neuroscience 790, Developmental Neurobiology
1995 Honors 596 (Undergraduate)- Contemporary Issues in Neuroscience
1996 Zoology 632 (Undergraduate)- Introduction to Neuroscience
1998 Neuroscience 797, Neuroscience Seminar
North Carolina State University:
2001 CBS 810- Special Topics, Stem Cell Biology
2001-2005 CBS 770, Cell Biology
2002 CBS 810- Special Topics- CBS Seminar, coordinator
9 2004 CBS 800- CBS Seminar
North Carolina Central University
2006- BIOG 5310, Cell Biology, team taught
2007 BIOL 4100, Developmental Biology, team taught
2007-2012 BIOG 5400, Physiology and Pharmacology I, team taught
2009- BIOG 5330, Fundamental Neuroscience, Course co-coordinator
2011-2014 BIOG 5700, Graduate Seminar
2011- BIOL 2040, Biology in Films
2013- BIOD 8010, Advanced Cell Biology
2013-2017 INBS 8100, Multidisciplinary Problem Solving
2013- BIOD 8060, Fundamental Neuroscience, Course co-coordinator
2016--2017 BIOD 8080, Advanced Physiology
2018- BIOL 2220, Molecular Biology of Cells II
Graduate Student Committees:
Medical University of South Carolina:
Craig McCabe, advisor, Ph.D. awarded 8/1992; Current position: Private practice in Ophthalmology, Murfreesboro, TN
Michael Burg, advisor, Ph.D. awarded 10/1993; Current position: Lecturer, UC-San Diego
Douglas Brees, co-advisor, Ph.D. awarded 9/1992
David Somers
Linda Roy
John Miller
10 Mark Hens
Ohio State University:
Guoshan Tsen, advisor, Ph.D. awarded 4/1997; Current Position: Global Vice President, Greater China, US Pharmacopeia
Audrey Napier, advisor, Ph.D. awarded 12/1998; Current Position: Professor and Chair, Dept. Biological Sciences, Alabama State University
Susan Cotman, advisor, Ph.D. awarded 11/1999: Current Position: Assistant Professor in Neurology, Harvard University, Boston, MA
Ju-Ahng Lee, advisor, Ph.D. awarded 8/2000; Current position: Associate Professor, Biological and Biomedical Sciences, and BBRI, North Carolina Central University
Eli Thomas, advisor, M.S. awarded 8/2000
Mary Weiler, co-advisor, Ph.D. awarded 5/1998
Jon Terman
Terrie Rife
Feng Bian
Li-Hsien Lin
Christine Kondratick
Jackie Crisman
Teresa Chu
Hongwen Ma
North Carolina State University:
Min Jung Kim, advisor, PhD awarded 8/2004; Current position: Associate Professor, Sook- Myung Women’s University, Korea
I-Hsuan Liu, advisor, Ph.D. awarded 3/2007: Current Position: Associate Professor, National Taiwan University, Taiwan
Chris Langdale
11 Gautam Ghatnekar
North Carolina Central University:
Advisor:
Oswald Boa-Amponsem, INBS PhD student, advisor, graduated 5/2020. Current position: Postdoc, UNC-Chapel Hill
Eintou Ford, co-advisor, graduated 12/2008
Qwan (Mickey) Turton, advisor, graduated 5/2011
Chantal Bodkin-Clarke, co-advisor, graduated 12/2009
Princess Ojiaku, advisor, graduated 6/2012
Vanessa Bell, advisor, graduated 6/2012
Jared Frazier, advisor, graduated 5/2014
Derek Burton, advisor, graduated 12/2016
Thesis/Dissertation committee member:
Tatiana Velasquez
Selena Johnson
Shailendra Devkota
Susana Hildebrandt
Damiyon Sledge
LaVita Anderson
Roketa Sloan
Brian Shackleford
Kristen Smith
Carla Perry
Krisstonia Spruiell
12
Ashely Bynum
TaCriasha Willoughby
Giovanni Anthony
Dal Khatri
Joab Oderi
Shaunacee Howell
Jennifer Echeverria
Stephanie Arvai
Brianna Harris
Kala Nwachukwu
Postdoctoral Trainees:
1989-1993 Margaret Kelly, Ph.D.
1999-2000 Susan L. Cotman, Ph.D.; Current Position: Assistant Professor in Neurology, Harvard Medical School, Boston, MA
2000-2004 Ju-Ahng Lee, Ph.D., Current Position: Associate Professor, North Carolina Central University
2000-2002 Mauricio Ramirez, Ph.D.
2007-2007 I-Hsuan Liu, Ph.D., Associate Professor, National Taiwan University, Taiwan
2007-2010 Chenjin Zhang, Ph.D., Current Position: Research Scientist, Syngenta, RTP
Undergraduate Research Trainees:
1998-2000 Anil Suryaprasad
1998-1999 Josh Martin
13 2002-2003 Brook Colgan
2002-2003 Laura Mitchell, Senior Honors Thesis in Biochemistry conducted in laboratory.
2003-2005 Laura Cooper, Senior Honors Thesis in Psychology conducted in laboratory.
2005-2006 Qwan M. Turton
2009-2011 Tatiana Velasquez
2011 Bryan Oliver, Charlotte Crone
2012 Kimberly Leathers, Duke Okeke, Barbara Turchie
2013 Twanda Andrews, Chenille Coston, Trokon Morgan
2014 Jamal Hoyte, Langston Harrison, Mescha Seabrook
2015 Desiree Sanders, Tamara Jeremic, Ashley Anderson, Octavious Johnson
2016 Octavious Johnson, Laquanda Fredericks, Darrell Johnson, Philomena Nwanze
2017 Romny Imbert, Philomena Nwanze, Iman Ardrey, Keshiyena Pieters
2018 Anirudh Bandi, Kweli Gale, Darrick Wiggins
2019 Natalie Ezem, Juliet Harris, Heiu Hoang, Tapanga Parham, Lauren Pearson
2020 David Emerson, Shauntrice Biles, Summer Wynne, Savoya Joyner
Society Membership:
Society for Neuroscience
American Society for Cell Biology
American Society for Matrix Biology
Sigma Xi, North Carolina Chapter
Research Society for Alcoholism
FASD Study Group
14
Invited Lectures:
November, 1984 Department of Biological Sciences, State University of New York, Albany
June, 1985 Department of Biological Sciences, University of California, Santa Barbara
March, 1986 Department of Biochemistry, University of Miami School of Medicine
December, 1986 Annual Meeting for American Society for Cell Biology Symposium Analysis of Neural Cell Adhesion Molecule from Gene to Embryo
January, 1987 Bascom Palmer Eye Institute, University of Miami
February, 1987 Miami Winter Symposium, The Molecular Biology of Development
February, 1987 Department of Anatomy and Cell Biology, Medical University of South Carolina
March, 1987 Mental Health Research Institute, University of Michigan
July, 1987 Gordon Research Conference on Neural Plasticity, Wolfeboro, NH
February, 1989 Rushton Lecturer, Current Problems in Psychobiology lecture series, Department of Biological Sciences, Florida State University
May 1990 Department of Neurobiology, Anatomy and Cell Science, University of Pittsburgh
February, 1991 Department of Pharmacological and Physiological Science, St. Louis University School of Medicine
March, 1992 La Jolla Cancer Research Foundation
April, 1992 Ohio State Biotechnology Center, The Ohio State University
May, 1994 Department of Physiology, The Ohio State University
July, 1994 Gordon Research Conference on Proteoglycans, Andover, NH
November, 1994 Ohio State Biochemistry Program, The Ohio State University
November, 1994 Neuroscience Graduate Program, The Ohio State University
15 March, 1995 Department of Neurosciences, Case Western Reserve University
September, 1995 Departments of Physiology and Anatomy & Cell Biology, Emory University School of Medicine
February, 1997 Division of Pharmacology, College of Pharmacy, The Ohio State University
January, 1998 Winter Conference on Brain Research, Snowbird, UT
June, 1998 Department of Anatomy, Physiology and Pharmacology, College of Veterinary Medicine, Auburn University
January, 2000 Department of Cell Biology and Anatomy, Louisiana State University Medical Center, New Orleans
March, 2000 Department of Anatomy, Physiology and Radiology, North Carolina State University, College of Veterinary Medicine
November, 2001 Department of Zoology, North Carolina State University
February, 2004 Department of Biology, Alabama State University, Montgomery, AL
January, 2005 Biomedical/Biotechnology Research Institute, North Carolina Central University, Durham, NC
April, 2007 North Carolina Research Campus Conference, Kannapolis, NC
October, 2007 Charlotte Biotechnology Conference, Charlotte, NC
September, 2009 Biomanufacturing Research Institute and Technology Enterprise (BRITE), North Carolina Central University, Durham, NC
January, 2010 Integrated Toxicology Program, Duke University, Durham, NC
February, 2010 Department of Anatomy and Cell Biology, East Carolina University, Brody School of Medicine, Greenville, NC
January, 2012 Integrated Toxicology Program, Duke University, Durham, NC
March, 2013 Biomanufacturing Research Institute and Technology Enterprise (BRITE), North Carolina Central University, Durham, NC
October, 2014 Center for Addiction and Behavior Change, Neurotoxic Consequences of Drug Abuse Symposium, Duke University, Durham, NC
November, 2017 Program in Neuroscience, Florida State University, Tallahassee, FL
16 July, 2018 Duke Summer Scholars Program, Durham, NC
April, 2019 2019 Triangle Society for Neuroscience Annual Meeting, Cary NC
Patents:
Provisional patent filed 10/08: “Zebrafish Alzheimer’s disease model”, Gregory J. Cole and Ju-Ahng Lee, co-inventors.
Bibliography
Published Articles:
1. Cole, G.J. and Elam, J.S. (1981). Axonal transport of glycoproteins in regenerating olfactory nerve: enhanced glycopeptide Concanavalin A binding. Brain Res. 222, 437-441.
2. Cole, G.J. and Elam, J.S. (1983). Characterization of axonally transported glycoproteins in regenerating garfish olfactory nerve. J. Neurochem. 41, 691-702.
3. Dyer, S.A., Derby, M.A., Cole, G.J. and Glaser, L. (1983). Identification of subpopulations of chick neural retinal cells by monoclonal antibodies: a fluorescence- activated cell sorter screening technique. Dev. Brain Res. 9, 197-203.
4. Cole, G.J. and Glaser, L. (1984). Identification of novel neural- and neural retina- specific antigens with a monoclonal antibody. Proc. Natl. Acad. Sci. USA 81, 2260- 2264.
5. Cole, G.J. and Glaser, L. (1984). Inhibition of embryonic neural retina cell-substratum adhesion with a monoclonal antibody. J. Biol. Chem. 259, 4031-4034.
6. Cole, G.J. and Glaser, L. (1984). Cell-substratum adhesion in embryonic chick central nervous system is mediated by a 170,000-mol. wt. neural specific polypeptide. J. Cell Biol. 99, 1605-1612.
7. Cole, G.J., Schubert, D. and Glaser, L. (1985). Cell-substratum adhesion in chick neural retina depends upon protein-heparan sulfate interactions. J. Cell Biol. 100, 1192-1199.
8. Cole, G.J. and Glaser, L. (1986). A heparin-binding domain from NCAM is involved in neural cell-substratum adhesion. J. Cell Biol. 102, 403-412.
17 9. Cole, G.J., Bond, R. and Glaser, L. (1986). Monoclonal antibodies specific for ganglion cells in the embryonic chick neural retina. Dev. Brain Res. 26, 133-143.
10. Cole, G.J., Loewy, A. and Glaser, L. (1986). Neuronal cell-cell adhesion depends upon interactions of NCAM with heparin-like molecules. Nature 320, 445-447. (see related News and Views, Nature (1986) 321, 731-732)
11. Cole, G.J., Loewy, A., Cross, N.V., Akeson, R., and Glaser, L. (1986). Topographic localization of the heparin-binding domain of the neural cell adhesion molecule NCAM. J. Cell Biol. 103, 1739-1744.
12. Cole, G.J. and Schachner, M. (1987). Localization of the L2 monoclonal antibody binding site on NCAM and evidence for its role in NCAM-mediated cell adhesion. Neurosci. Lett. 78, 227-232.
13. Cole, G.J., Schachner, M. and Fliesler, S.J. (1988). N-linked oligosaccharides are not required for neuron-neuron interactions mediated by neural cell adhesion molecule. Neurosci. Lett. 93, 170-175.
14. Cole, G.J. and Akeson, R. (1989). Identification of a heparin-binding domain of the neural cell adhesion molecule NCAM using synthetic peptides. Neuron 2, 1157-1165.
15. Cole, G.J. and Burg, M. (1989). Characterization of a heparan sulfate proteoglycan that co-purifies with neural cell adhesion molecule. Exp. Cell Res. 182, 44-60.
16. Burg, M. and Cole, G.J. (1990). Characterization of cell-associated proteoglycans synthesized by embryonic neural retinal cells. Arch. Biochem. Biophys. 276, 396- 404.
17. Fliesler, S.J., Cole, G.J. and Adler, A.J. (1990). Neural cell adhesion molecule (NCAM) in adult vertebrate retinas: tissue localization and evidence against its role in retina- pigment epithelium adhesion. Exp. Eye Res. 50, 475-482.
18. Reyes, A.A., Akeson, R., Brezina, L. and Cole, G.J. (1990). Structural requirements for neural cell adhesion molecule-heparin interaction. Cell Regulation 1, 567-576.
19. Cole, G.J. and McCabe, C.F. (1991). Identification of a developmentally-regulated keratan sulfate proteoglycan that inhibits cell adhesion and neurite outgrowth. Neuron 7, 1007-1018.
20. McCabe, C.F., Thompson, R.P. and Cole, G.J. (1992). Distribution of the novel developmentally regulated protein EAP-300 in the embryonic chick nervous system. Dev. Brain Res. 66, 11-23.
21. McCabe, C.F. and Cole, G.J. (1992). Expression of the barrier-associated proteins EAP-300 and claustrin in the developing central nervous system. Dev. Brain Res.70, 9-24.
18 22. Burg, M.A. and Cole, G.J. (1994). Claustrin, an anti-adhesive neural keratan sulfate proteoglycan, is structurally related to MAP1B. J. Neurobiol. 25, 1-22.
23. Burg, M.A., Halfter, W. and Cole, G.J. (1995). Analysis of proteoglycan expression in developing chick brain: Characterization of a heparan sulfate proteoglycan that interacts with the neural cell adhesion molecule NCAM. J. Neurosci. Res.41, 49-64.
24. Kelly, M.M., Phanhthourath, C., Brees, D.K., McCabe, C.F., and Cole, G.J. (1995). Molecular characterization of EAP-300: a high molecular weight, embryonic polypeptide containing an amino acid repeat comprised of multiple leucine-zipper motifs. Dev. Brain Res. 85, 31-47.
25. Tsen, G., Halfter, W., Kröger, S., and Cole, G.J. (1995). Agrin is a heparan sulfate proteoglycan. J. Biol. Chem. 270, 3392-3399.
26. McCabe, C.F., Gourdie, R.G., Thompson, R.P. and Cole, G.J. (1995). The developmentally regulated neural protein EAP-300 is expressed by myocardium and cardiac neural crest during chick embryogenesis. Dev. Dynamics 203, 51-60.
27. Tsen, G., Napier, A., Halfter, W., and Cole, G.J. (1995). Identification of a novel alternatively spliced agrin mRNA that is preferentially expressed in non-neuronal cells. J. Biol. Chem. 270, 15934-15937.
28. Cole, G.J. and Halfter, W. (1996). Agrin: an extracellular matrix heparan sulfate proteoglycan involved in cell interactions and synaptogenesis. Perspectives on Develop. Neurobiol. 3, 359-371.
29. Storms, S.D., Kim, A.C., Tran, B.-H. T., Cole, G.J., and Murray, B.A. (1996). NCAM-mediated adhesion of transfected cells to agrin. Cell Adhesion and Commun. 3: 497-509.
30. Brees, D.K., Hutchison, F.N., Cole, G.J., and Williams, J.C.Jr. (1996). Differential effects of diabetes and glomerulonephritis on glomerular basement membrane composition. Proc. Soc. Exp. Biol. Med. 212, 69-77.
31. Halfter, W., Schurer, B., Yip, J., Yip, L., Tsen, G., Lee, J.-A., and Cole, G.J. (1997). Distribution and substrate properties of agrin, a heparan sulfate proteoglycan of developing axonal pathways. J. Comp. Neurol. 383, 1-17.
32. Yuan, Y., Lee, J.-A., Napier, A., and Cole, G.J. (1997). Molecular cloning of a new intermediate filament protein expressed by radial glia and demonstration of alternative splicing in a novel heptad repeat region located in the carboxy-terminal tail domain. Mol. Cell. Neurosci. 10, 71-86.
33. Cole, G.J. and Lee, J.-A. (1997). Immunocytochemical localization of a novel radial glial intermediate filament protein. Dev. Brain Res. 101, 225-238.
19 34. Burg, M.A., Lee, J.-A. and Cole, G.J. (1997). An alternatively spliced, 5’-truncated MAP1B isoform is expressed in the developing chick nervous system. J. Mol. Neurosci., 9, 177-186.
35. Ma, X., Charron, F., Cole, G.J., Savard, P.E., and Vincent, M. (1998). The developmentally regulated avian protein IFAPa-400 is transitin. Dev. Brain Res. 109, 59-66.
36. Halfter, W., Dong, S., Schurer, B. and Cole, G.J. (1998). Collagen XVIII is a basement membrane heparan sulfate proteoglycan. J. Biol. Chem. 273, 25404-25412.
37. Cotman, S.L., Halfter, W. and Cole, G.J. (1999). Identification of extracellular matrix ligands for the heparan sulfate proteoglycan agrin. Exp. Cell Res. 249, 54-64.
38. Napier, A., Yuan, Y. and Cole, G.J. (1999). Characterization of the chicken transitin gene reveals a strong relationship to the nestin intermediate filament class. J. Mol. Neurosci. 12, 11-22.
39. Cheng, G., Litchenberg, W.H., Cole, G.J., Mikawa, T., Thompson, R.P. and Gourdie, R.G. (1999). Development of the cardiac conduction system involves recruitment within a multipotent cardiomyogenic lineage. Development 126, 5041-5049.
40. Lee, J.-A. and Cole, G.J. (2000). Localization of transitin mRNA, a nestin-like intermediate filament family member, in chicken radial glia processes. J. Comp. Neurol. 418, 473-483.
41. Cotman, S.L., Halfter, W. and Cole, G.J. (2000). Agrin binds to ß-amyloid (Aß), accelerates Aß fibril formation, and is localized to Aß deposits in Alzheimer’s Disease brain. Mol. Cell. Neurosci. 15, 183-198. (see related Commentaries, J. Neurol. (2000) 247,663-664; TINS (2000) 23, 386)
42. Halfter, W., Dong, S., Schurer, B., Osanger, A., Schneider, W., Ruegg, M., and Cole, G.J. (2000). Composition, synthesis and assembly of the embryonic chick retinal basal lamina. Dev. Biol. 220, 111-128.
43. Henion, P.D., Blyss, G.K., Luo, R., Maynard, T.M., An, M. Cole, G.J., and Weston, J.A. (2000). Avian transitin expression mirrors glial cell fate restrictions during neural crest development. Dev. Dynamics 218, 150-159.
44. Darenfed, H., Ma, X., Davis, L., Juge, N., Savard, P.E., Cole, G.J., and Vincent, M. (2001). Molecular polymorphism of the intermediate filament protein transitin. Histochem. Cell Biol. 116, 397-409.
45. Dong, S., Landfair J., Balasubramani M., Bier M. E., Cole G., and Halfter W. (2002). Expression of basal lamina protein mRNAs in the early embryonic chick eye. J. Comp. Neurol. 447, 261-273.
20 46. Strohmeyer, R., Ramirez, M., Cole, G.J., Mueller, K., and Rogers, J. (2002). Association of Factor H of the alternative pathway of complement with agrin and complement receptor 3 in Alzheimer’s Disease brain. J. Neuroimmunology 131, 135-146.
47. Dong, S., Cole, G.J. and Halfter, W. (2003). Expression of collagen XVIII and localization of its glycosaminoglycan (GAG) attachment sites. J. Biol. Chem. 278, 1700- 1707.
48. Kim, M.J., Cotman, S.L., Halfter, W. and Cole, G.J. (2003). The heparan sulfate proteoglycan agrin modulates neurite outgrowth mediated by FGF-2. J. Neurobiol. 55, 261-277.
49. Winzen U., Cole G.J. and Halfter W. (2003). Agrin is a chimeric proteoglycan with the attachment sites for heparan sulfate/chondroitin sulfate located in two multiple serine- glycine clusters. J. Biol. Chem. 278, 30106-30114.
50. Halfter, W., Dong, S., Schurer, B., Ring, C., Cole, G.J. and Eller, A. (2005). Embryonic synthesis of the inner limiting membrane and vitreous body. Invest. Ophth. Vis. Sci., 46, 2202-2209.
51. Liu, I.-H., Uversky, V.N., Munishkina, L.A., Fink, A.L., Halfter, W., and Cole, G.J. (2005). Agrin binds a-synuclein and modulates a-synuclein fibrillation. Glycobiology 15, 1320-1331.
52. Kim, M.J., Liu, I.-H., Song, Y., Lee, J.-A., Halfter, W., Balice-Gordon, R.J., Linney, E., and Cole, G.J. (2007). Agrin is required for posterior development and motor axon outgrowth and branching in embryonic zebrafish. Glycobiology 17, 231-247.
53. Candiello, J., Balasubramani, M., Schreiber, E.M., Cole, G.J., Mayer, U., Halfter, W., and Lin, H. (2007). Biomechanical properties of native basement membranes. FEBS J. 274, 2897-2908.
54. Wakamatsu, Y., Nakamura, N., Lee, J.-A., Cole, G.J., and Osumi, N. (2007) Transitin, a Nestin-like intermediate filament protein, mediates cortical localization and lateral transport of Numb in mitotic avian neuroepithelial cells. Development 134, 2425-2433.
55. Lee, J.-A. and Cole, G.J. (2007). Generation of transgenic zebrafish expressing green fluorescent protein under control of zebrafish amyloid precursor polypeptide gene regulatory elements. Zebrafish 4, 277-286.
56. Lee, J.-A., Anholt, R.R. H. and Cole, G.J. (2008). Olfactomedin-2 mediates development of the anterior central nervous system and head structures in zebrafish. Mech. Dev. 125, 167-181.
57. Liu, I.-H., Zhang, C., Kim, M.J. and Cole, G.J. (2008). Retina development in zebrafish requires the heparan sulfate proteoglycan agrin. Dev. Neurobiol. 68, 877-898.
58. Hu, B., Zhang, C., Baawo, K., Qin, R., Cole, G.J., Lee, J.-A., and Chen, X. (2010).
21 Zebrafish K5 promoter driven GFP expression as a transgenic system for oral research. Oral Oncology 46, 31-37.
59. Candiello, J., Cole, G.J., and Halfter, W. (2010). Age-dependent changes in the structure, composition and biophysical properties of a human basement membrane. Matrix Biol 29, 402-410.
60. Jallouli, M., Lapierre, L.R., Guerette, D., Blais, K., Lee, J.-A., Cole, G.J., and Vincent, M. (2010). Transitin is required for the differentiation of avian QM7 myoblasts into myotubes. Dev. Dynamics 239, 3038-3047.
61. Zhang, C., Turton, Q.M., MacKinnon, S., Sulik, K.K. and Cole, G.J. (2011). Agrin function associated with ocular development is a target of ethanol exposure in embryonic zebrafish. Birth Defects Res. (Part A) 91, 129-141.
62. Xiao, T., Robles, E., Staub, W., Gosse, N.J., Cole, G.J., and Baier, H. (2011). Assembly of lamina-specific neuronal connections by a Slit gradient anchored to type IV collagen. Cell 146, 164-176.
63. Zhang, C., Ojiaku, P. and Cole, G.J. (2013). Forebrain and hindbrain development in zebrafish is sensitive to ethanol exposure involving agrin, Fgf and Sonic hedgehog function. Birth Defects Res. (Part A) 97, 8-27.
64. Hu, B., Chen, H., Liu, X., Zhang, C., Cole, G.J., Lee, J.-A., and Chen, X. (2013). Transgenic overexpression of zCdx1b in zebrafish induces metaplastic changes of gene expression in zebrafish esophageal squamous epithelium. Zebrafish 10, 218-227.
65. Zhang, C., Frazier, J.M., Chen, H., Liu, Y., Lee, J.AA., and Cole, G.J. (2014). Molecular and morphological changes in zebrafish following transient ethanol exposure during defined developmental stages. Neurotoxicol. Teratol. 44, 70-80.
66. Bailey, JM, Oliveri, AN, Zhang, C, Frazier, JM, Mackinnon, S, Cole, GJ and Levin ED (2015). Long-term behavioral impairment following acute embryonic ethanol exposure in zebrafish. Neurotoxicol. Teratol. 48, 1-8.
67. Zhang, C, Anderson, A and Cole GJ (2015). Analysis of crosstalk between retinoic acid and sonic hedgehog pathways following ethanol exposure in embryonic zebrafish. Birth Defects Res (Part A) 103, 1046-1057.
68. Burton, D, Zhang, C, Boa-Amponsem, O, Mackinnon, S, and Cole, GJ. (2017). Long- term behavioral changes as a result of acute ethanol exposure in zebrafish: evidence for a role for sonic hedgehog but not retinoic acid signaling. Neurotoxicol. Teratol. 61, 66-73.
69. Zhang, C*, Boa-Amponsem, O*, and Cole, GJ. (2017). Comparison of molecular marker expression in early zebrafish brain development following chronic ethanol or morpholino treatment. Exp. Brain Res. 235, 2413-2423.
22 70. Fish EW, Murdaugh LB, Zhang C, Boschen KE, Boa-Amponsem O, Medoza-Romero HN, Tarpley M, Chdid L, Mukhopadhyay S, Cole GJ, Williams KP, and Parnell SE. (2019). Cannabinoids exacerbate alcohol teratogenesis by a CB1-hedgehog interaction. Scientific Reports, 9:16057 | https://doi.org/10.1038/s41598-019-52336-w.
71. Boa-Amponsem O, Zhang C, Mukhopadhyay S, Ardrey, A, and Cole GJ. (2019). Ethanol and cannabinoids interact to alter behavior in a zebrafish fetal alcohol spectrum disorder model. Birth Defects Research 111, 775-788.
72. Boa-Amponsem O, Zhang C, Burton DF, Williams KP, and Cole GJ. (2020). Ethanol and cannabinoids regulate zebrafish GABAergic neuron development and behavior in a sonic hedgehog and fibroblast growth factor dependent mechanism. Alcohol. Clin. Exp. Res. 44, 1366-1377.
Book Chapters/Reviews:
1. Cancalon, P., Cole, G.J. and Elam, J.S. (1982). The role of axonal transport in the growth of the olfactory nerve axons. In D. Weiss and A. Gorio, eds., Axoplasmic Transport in Physiology and Pathology, Springer-Verlag, Berlin, pp. 62-69.
2. Cole, G.J. and Glaser, L. (1987). Characterization of the heparin-binding domain of the neural cell adhesion molecule NCAM. In Advances in Gene Technology: the Molecular Biology of Development, ICSU Short Reports, Vol. 7, Cambridge University Press, Cambridge, pp. 120-121.
3. Cole, G.J. and Bond, R.W. (1987). Neuronal antigens involved in cell adhesion and cell recognition. In Elson, E., Frazier, W. and Glaser, L., eds., Cell Membranes: Methods and Reviews Vol. 3, Plenum Press, New York, pp. 79-111.
4. Cole, G.J. and Liu, I.-H. (2006). Glycosaminoglycans, proteoglycans and conformational disorders. In V. Uversky and A.L. Fink, eds., Protein Misfolding, Aggregation and Conformational Diseases, Part A, Protein Aggregation and Conformational Diseases, Springer , New York, NY, pp. 83-100.
5. Cole, G.J., Zhang, C., Ojiaku, P., Bell, V., Devkota, S., and Mukhopadhyay, S. (2012). Effects of ethanol exposure on nervous system development in zebrafish. In Jeon, K.W., International Review of Cell and Molecular Biology Vol. 299, pp 255-315.
Published Abstracts:
1. Cole, G.J. and Elam, J.S. (1981). Axonal transport of Con A-binding glycopeptides in regenerating nerve. Trans. Am. Soc. Neurochem. 12, 247.
23 2. Cole, G.J. and Elam, J.S. (1982). Analysis of transported Con A-binding glycoproteins in regenerating nerve. Trans. Am. Soc. Neurochem. 13, 224.
3. Cole, G.J., Dyer, S.A., Derby, M.A. and Glaser, L. (1983). Developmental regulation of cell surface antigens in chick neural retina. Neurosci. Soc. Abst. 9, 944.
4. Cole, G.J., Loewy, A. and Glaser, L. (1986). Binding of heparin to NCAM is involved in neuronal cell interactions. Trans. Am. Soc. Neurochem. 17, 141.
5. Cole, G.J., Maimone, M.M., Tollefson, D.M., Loewy, A., and Glaser, L. (1986). Characterization of NCAM structure and function. J. Cell Biol. Abst. 103, 145a.
6. Cole, G.J., Burg, M. and Jiang, W. (1987). Characterization of neuronal heparan sulfate proteoglycans. J. Cell Biol. Abst. 105, 299a.
7. Cole, G.J., Schachner, M. and Fliesler, S.J. (1988). N-linked oligosaccharides are not required for NCAM function. Invest. Ophthalmol. Vis. Res. (ARVO Suppl.) 29, 386.
8. Cole, G.J. and Akeson, R.A. (1988). Identification of a heparan sulfate-binding amino acid sequence in NCAM. J. Cell Biol. Abst. 107, 730a.
9. Burg, M. and Cole, G.J. (1989). Interactions of neural HSPG with the neural cell adhesion molecule (NCAM). J. Cell Biol. Abst. 109, 233a.
10. Kelly, M.M., Brees, D. and Cole, G.J. (1990). Characterization of a developmentally regulated neural antigen. UCLA Colloquium, Cell and Molecular Aspects of the Developing Nervous System. J. Cell. Biochem. Suppl. 14F, 18.
11. McCabe, C.F., Thompson, R.P. and Cole, G.J. (1990). Distribution of a novel developmentally regulated polypeptide expressed in cardiac and neural tissues during chick embryogenesis. J. Cell Biol. Abst. 111, 243a.
12. Cole, G.J. and McCabe, C.F. (1991). Inhibition of neural cell adhesion and neurite outgrowth by a developmentally-regulated keratan sulfate proteoglycan. J. Cell Biol. Abst. 115, 442a.
13. Burg, M.A. and Cole, G.J. (1991). Analysis of the major proteoglycans of chick brain during development. J. Cell Biol. Abst. 115, 127a.
14. McCabe, C.F., Beckstead, R.M. and Cole, G.J. (1992). Expression of the barrier- associated proteins EAP-300 and claustrin in the developing central nervous system. Neurosci. Soc. Abst. 18, 577.
15. Burg, M.A. and Cole, G.J. (1992). A neural keratan sulfate proteoglycan, claustrin, is recognized by antibodies to MAP1B. Neurosci. Soc. Abst. 18, 236.
16.Tsen, G., Halfter, W., Kröger, S., and Cole, G.J. (1994). Agrin is a heparan sulfate proteoglycan. Mol. Biol. Cell 5S, 300a.
24
17. Tsen, G., Napier, A., Halfter, W., and Cole, G.J. (1995). Identification of a novel agrin isoform preferentially expressed in non-neuronal cells. Neurosci. Soc. Abst., 21, 1777.
18. Murray, B.A., Storms, S.D., Kim, A.S., Tran, B.-H.T., and Cole, G.J. (1995). Heterophilic NCAM-mediated adhesion of transfected cells to agrin from embryonic chick brain. Neurosci. Soc. Abst. 21, 1311.
19. Lee, J.-A., Yuan, Y., Napier, A., and Cole, G.J. (1996). The midline radial glial protein transitin defines a new class of intermediate filament protein. Neurosci. Soc. Abst. 22, 310.
20. Cotman, S.L., Halfter, W. and Cole, G.J. (1998) Identification of extracellular matrix ligands for the heparan sulfate proteoglycan agrin. Mol. Biol. Cell 9S: 46a.
21. Lee, J.-A. and Cole, G.J. (1998). Transport of mRNA encoding the intermediate filament protein transitin in radial glial processes. Mol. Biol. Cell 9S: 57a.
22. Cotman, S.L., Halfter, W. and Cole, G.J. (1999). Evidence of a role for agrin in ß- amyloid (Aß) aggregation and persistence in Alzheimer’s disease. Mol. Biol. Cell 10S, 60a.
23. Kim, M.J., Cotman, S.L., Halfter, W. and Cole, G.J. (2002). Modulation of laminin- and FGF-mediated neurite outgrowth by agrin. Mol. Biol. Cell 13S, 341a.
24. Lee, J.-A. and Cole, G.J. (2002). Transitin, a chicken nestin-like intermediate filament protein, is required for establishing radial glial cell morphology. Mol. Biol. Cell 13S, 123a.
25. Colgan, B., Uversky, V.N., Fink, A. L., Halfter, W., and Cole, G.J. (2002). Agrin modulates -synuclein fibrillation. Mol. Biol. Cell 13S, 341a.
26. Darenfed, H, Xiaoying, M., Guérette, D., Lee, J-A., Cole, G.J., and Vincent, M. (2002). Distribution of transitin in myogenic and neurogenic cells: Potential involvement of a leucine zipper like motif. Mol. Biol. Cell 13S, 61a.
27. Cole, G.J., Uversky, V.N., Liu I., Munishkina, L.A., Mitchell, L., Colgan, B.K., Fink, A.L., and Halfter, W. (2003). Agrin modulates amyloid formation in Alzheimer’s and Parkinson’s diseases. Soc. Neurosci. Abst., 297.20
28. Kim, M.J., Halfter, W. and Cole, G.J. (2003). The heparan sulfate proteoglycan agrin is required for posterior development and the formation of axonal pathways in zebrafish. Mol. Biol. Cell Abst. 297.20.
29. Brown, S.C., Torelli, S., Feng, L., Cole, G.J., Sewry, C.A., and Muntoni, F. (2003). Immunocytochemical analysis of muscle agrin in MDC1C and LGDM2I. Neuromusc. Disorders 13, 649.
25 30. Kim, M.J., Liu-I.-H., Halfter, W., and Cole, G.J. (2004). Agrin regulates the development of CNS structures that require Fgf signaling pathways. Mol. Biol. Cell Abst., 2511.
31. Lee, J.-A., Cooper, L., and Cole, G.J. (2004). Analysis of transitin function in radial glia following RNA interference. Mol. Biol. Cell Abst., 1634.
32. Lee, J.-A., Anholt, R.R.H. and Cole, G.J. (2005). Role of olfactomedin-2 in zebrafish central nervous system development. Soc. Neurosci. Abst. 596.6.
33. Liu, I.-H., Kim, M.J., Halfter, W. and Cole, G.J. (2005). Modulation of Fgf signaling by agrin during zebrafish development. Soc. Neurosci. Abst. 597.11.
34. Guérette, D., Trépanier, J., Savard, P., Lee, J.-A., Cole, G.J., and Vincent, M. (2005). The C-terminal heptad repeat domain of transitin: a second module able to interact with intermediate filament proteins. Mol. Biol. Cell Abst., L177.
35. Liu, I.-H. and Cole, G.J. (2006). The heparan sulfate proteoglycan agrin modulates retinal development in zebrafish. Soc. Neurosci. Abst. 420.3.
36. Lee, J.-A., Anholt, R.R.H. and Cole, G.J. (2006). Olfactomedin 2 mediates branchiomotor neuron axon guidance in developing zebrafish. Soc. Neurosci. Abst. 319.14.
37. Lee, J.-A., Zhang, C. and Cole, G.J. (2008). Generation of transgenic zebrafish expressing GFP under control of gene regulatory elements from the zebrafish amyloid precursor protein. Soc. Neurosci. Abst. 441.9.
38. Bodkin-Clarke, C., Cole, G.J. and Lee, J.-A. (2009). Generation of transgenic zebrafish expressing cytotoxic beta-amyloid (Aß42) peptides as a novel Alzheimer’s disease model. Mol. Cell Biol. Abst., 919.
39. Turton, Q.M., MacKinnon, S., Zhang, C., and Cole, G.J. (2009). Molecular basis of ethanol on eye and neural crest development in zebrafish. Mol. Cell Biol. Abst., 1658.
40. Zhang, C., Turton, Q.M., MacKinnon, S., Liu, I.-H., Sulik, K.K. and Cole, G.J. (2010). Agrin function during ocular development is a target of ethanol exposure in embryonic zebrafish. Soc. Neurosci. Abst., 573.20.
41. Zhang, C., MacKinnon, S., Frazier, J., Tarchie, B., Okeke, D., Andrews, T. and Cole, G.J. (2013). Mechanisms of ethanol-induced CNS abnormalities in zebrafish: effect of acute exposure on morphological phenotypes and gene expression. Alcohol Clin. Exp. Res. Abst., 49A.
42. Frazier, J.M., Zhang, C., Oliver, A., Bailey, J., Mackinnon, S., Levin, E.D. and Cole, G.J. (2013). Effect of binge-like alcohol exposure on nervous system development and behavior in Zebrafish. Soc. Neurosci. Abst., 154.22.
26 43. Oliveri, A., Bailey, J., Zhang, C., Frazier, J., Cole, G.J. and Levin, E.D. (2013). Zebrafish Embryos Exposed briefly to Alcohol Show Long-term Behavioral Dysfunction. Neurobehav. Teratology Soc. Abstract.
44. Zhang, C., Bailey, J.M., Oliveri, A.N., Frazier, J., DeLaRosa, A., Crosby, E., Janardhan, S., Mackinnon, S., Levin, E.D., and Cole, G.J. (2014). Long-term behavioral effects of embryonic ethanol exposure in zebrafish. Alcohol Clin. Exp. Res. Abst 704A.
45. Zhang, C., Mackinnon, S., Anderson, A. and Cole, G.J. (2015). Is crosstalk between multiple extracellular signaling pathways responsible for ethanol-mediated disruption of ocular development? Alcohol Clin Exp Res Abst 352A.
46. Burton, D., Zhang, C., Mackinnon, S., Johnson, O., Cole, G.J. (2016). Analysis of gene- ethanol interactions and effects on zebrafish behavior. Alcohol Clin Exp Res Abst, 309A.
47. Boa-Amponsem, O, Burton DF, Zhang, C, Mackinnon, S, Nwanze PM, and Cole GJ. (2017). Effects of multiple binge ethanol exposures on zebrafish morphology and behavior. Alcohol Clin Exp Res Abst, 110A.
48. Boa-Amponsem, O, Burton, D, Zhang, C, Mackinnon, S, Nwanze, P and Cole, GJ. (2017). Analysis of gene-ethanol interactions and effects on behavior in zebrafish. Triangle Soc. Neurosci. Annual Meeting, 17.
49. Boa-Amponsem, O, Zhang, C, Mukhopadhyay, S, Mackinnon, S, Parnell, SE, Fish, EW, and Cole GJ. (2018). Binge ethanol and endocannabinoid exposure induce FASD phenotypes and behavioral changes in zebrafish. Alcohol Clin Exp Res Abst, 233A.
50. Burton, DF, Hopkins, M, Fish, EW, Parnell, SE, Cole, GJ and Williams KP. (2018). Pharmacological activation of the sonic hedgehog pathway diminishes severity of alcohol-induced birth defects in zebrafish. Alcohol Clin Exp Res Abst, 106A.
51. Boa-Amponsem, O, Zhang, C, Cole GJ. (2019). Analysis of the role of Fgf and Shh signaling in zebrafish GABAergic neuron development following exposure to ethanol and cannabinoids. Alcohol Clin Exp Res Abst, P573.
52. Harris, K and Cole, GJ (2019). Transgenerational effects of ethanol and cannabinoids on zebrafish behavior. Alcohol Clin Exp Res Abst, P575.
53. Burton DF, Herbin TJ, Hopkins M, Boa-Amponsem OM, Dixon SM, Fish EW, Cole GJ, Parnell SE, and Williams KP. (2019). Gene-ethanol interactions and behavior: zebrafish as a model of FASD. Alcohol Clin Exp Res Abst, P558.
54. Zhang C, Lee JA, Cole GJ (2020). Effects of ethanol and cannabinoids on zebrafish cardiac development: a role for agrin, FGF and Shh signaling. Alcohol Clin Exp Res Abst, In Press.
27 55. Burton, DF, Hopkins, M, Dixon, MS, Boa-Amponsem, OM, Zhang, C, Fish, EW, Parnell, SE, Cole, GJ, Williams, KP (2020). Pharmacological Activation of the Sonic Hedgehog Pathway Diminishes the Severity of Alcohol-Induced Birth Defects in a Zebrafish Model of FASD. Alcohol Clin Exp Res Abst, In Press.
28