RESUME

DR. MOHAMMAD HAYATUL ISLAM

Assistant Professor Department of Biosciences , E-Mail: [email protected] Contact No: +91-9368134040

Professional and academic qualification

Degree Year of Subject University %Marks passing Ph.D. 2014 Biotechnology Integral University, Awarded Lucknow

M.Sc. 2010 Biotechnology Integral University, 80.35 Lucknow (Awarded Silver Medal for being second topper) PG Diploma 2010 Nano- Life Science 80.00 (Distance) Biotechnology Foundation of India Karnataka

B.Sc. 2008 Zoology and Botany M.J.P. Rohilkhand 72.59 University,

Teaching &Research Experience (Total Research and Teaching: 8 years) (Total Teaching Experience: 4 years) Work Experience. Position Held Name of the University From To Pay Scale

Assistant Professor Department of Integral 11-07-2014 Till date 15600-39100 University, Lucknow with Grade Pay of Rs. 6600/- Chief Warden Integral University, 11-07-2014 08-01-2018 (Boys and Girls Lucknow Hostel) Assistant Warden Integral University, 01-01-2011 11-07-2014 - (Boys Hostel) Lucknow

Major Research Area: Phytotherapy, Neurodegenerative disease, Cancer Biology, Bioinformaics Major Teaching Area: Biotechnology, Molecular Biology, Biochemistry, Metabolism, Enzyme Technology Ph.D. Thesis Title: Study of pharmacological activities of Nigella sativa seed extracts in different germination stages.

 Subject teaching in Integral University, Lucknow On graduation level  Metabolism (Code BS201), B.Sc. Biotechnology, 2nd Year  Molecular Biology (Code BS212) B.Sc. Biotechnology, 2nd Year  Bioinformatics (Code BS301) B.Sc. Biotechnology, 3rd Year  Animal Sciences Laboratory (Code BS114) B.Sc. Life sciences 1st Year

On Post graduation level  Essential of Molecular Biology (Code BS403) M.Sc. Microbiology, 1st Year  Enzymes and Enzyme kinetics (Code BS412) M.Sc. Biochemistry and Biotechnology, 1st Year  Clinical and Physiological Biochemistry (Code BS415) M.Sc. Biochemistry, 2nd Year  Animal Biotechnology (Code BS416) M.Sc. Biotechnology  Microbiology and Bioinformatics Laboratory Code BS456) M.Sc. Microbiology, 1st Year

Computer Education

Advanced diploma in computer software technology (2008), from Industrial Research, Education and Training Institute. Affiliated by DOEACC, Ministry of communication & Information Technology, Govt. of India.

Techniques/Instrument/Computer skills

Techniques known:

Animal tissue culture (In vitro animal cell Handling of various cell lines. (Skin cell line culture, MTT, SRB, ROS assays etc). Study (keratinocyte), Hepatocarcinoma cell line of anticancer effect of various drugs and (HepG2), Lungs cancerous cell line (A549), plant extracts on cancer cell line. Study of Hep2, squamous cell line etc.) various carcinogens on cell line. Plant Tissue Culture: In vitro callus Pharmacological techniques (In vivo study on culure, suspention culture, synthetic seed animal model) such as: Animal handling, production, secondary metabolites Analgesic and anti-inflammatory test, production. Enhancement of various Hepatoprotective effect of drugs, metabolites in plant by plant tissue culture Neuroprotective test, Anxiolytic, Locomotor, technique. antiepileptic and anti depressant test. Isolation and and Maintenance of Chromatography (TLC & Paper), separation cyanobacterial (Blue Green Algae) strains. of Bioactive compounds using Thin Layer Study of UV-B protecting compound in Chromatography. blue green algae under UV-B radiation. SDS-PAGE and agarose gel Microbiological Techniques for the electrophoresis. Immunological maintenance of culture, antibiotic sensitive Techniques: Blood group detection, test, MIC test, Idententification and isolation ELISA, In vitro immunomodulatory effect of MDR bacteria from human patient etc. testing etc. Biochemical Assays: Qualitative and Bioinformatics tools. Molecular Docking (by Quantitative analysis by using AutoDock software) such as: protein-protein spectrophotometer, analysis of secondary interaction, drug-protein interaction, drugs- metabolites and enzymes. receptors interaction etc.

Instrumentation Skill: PC based Spectrophotometer, PCR,Plethismometer, Analgesiometer, Actophotometer, Electroconvulsometer, Fluorescence microscope, Light microscope, ELISA reader, Laminar flow chamber, Autoclave, Oven, Incubator shaker, Centrifuge Machine, Digital pH meter, MQ machine. Computer skills:

Microsoft PowerPoint, Microsoft office , Microsoft Excel,  Adobe Photoshop,  Microsoft

Publisher,  Microsoft Access Browsers, Outlook, HTML Conversion Tools,  internet Explorer,  HTML Authoring Tools, SPSS, Sigma plot 10, Prism. Chemsketch.

Urdu Literature Education

Adeeb, (2001) from Jamia Urdu Aligarh, U.P. India, secured 53 % marks. Adeeb-e-Mahir, (2002) from Jamia Urdu Aligarh, U.P. India, secured 53.6 % marks. Adeeb-e-Kamil, (2003) from Jamia Urdu Aligarh, U.P. India, secured 50 % marks. Moallim-e-Urdu (2004-05). from Jamia Urdu Aligarh, U.P. India, secured 60.10 % marks

Publications Book: Title: Antioxidant Potential of Nigella sativa in Germination Stages Publisher: LAP Lambert Academic Publishing, 2012 ISBN: 3848445581, 9783848445585 Length: 196 pages Subjects: Science / Life Sciences / Biochemistry

Full Research Paper:

S.No. Author(s) Title Name of Journal Vol. Page No. Year 1. Akanksha Sharma, Deciphering the Journal of Vol 026-034 2018 Mohammad Hayatul Binding of Natural Applied 8 Islam, Nida Fatima, Pharmaceutical (05), Terpenoids to Tarun K Upadhyay,M. Science Kalim A. Khan, Mycobacterium c Upendra N. Dwivedi tuberculosis Type III and Rolee Sharma Polyketide Synthase18

(PKS18): An In-Silico Approach 2. Khatoon A, Khan F, Green Synthesis of Life sciences 209 430-434 2018 Ahmad N, Shaikh S, silver nanoparticles Rizvi SMD, Shakil using leaf extract S, Islam M H, Iqbal of Menthapiperita and D, Dutta R study of their effects on acetylcholinesterase activity. 3. Mohammad Neuroprotective Pharmacognosy 11(1) 182-189 2015 Hayatul Islam, Iffat effects of Nigella Magazine Zareen Ahmad and sativa extracts Mohammad Tariq during germination Salman on central nervous system. 4. Mohammad Enhancement in Pharmacognocy 5 1-3 2014 Hayatul Islam, Iffat anti-inflammatory journal Zareen Ahmad and and analgesic Mohammad Tariq activities of Nigella Salman sativa seed during germination. 5. Mohammad In vivo evaluation of International 5(4) 451-454 2013 Hayatul Islam, Iffat anti-inflammatory Journal of Zareen Ahmad and and analgesic Pharmacy and Mohammad Tariq activities of Nigella Pharmaceutical Salman sativa seed during Sciences germination. 6. Mohammad Antibacterial activity E3 Journal of 4(1) 8-13 2013 Hayatul Islam, Iffat of Nigella sativa Biotechnology Zareen Ahmad and seed in various and Mohammad Tariq germination phases Pharmaceutical Salman on clinical bacterial Research strains isolated from human patients. 7. Kamal, M.H. Islam Hydroxyl Free International 1 (4) 203-208 2010 and I. Z. Ahmad Radical Scavenging Journal of Activity of Nigella Biological Sativa L. Seed Sciences and Extracts in various Engineering Germinating Stages under Cadmium Stress. 8. Aisha Kamal, Iffat Alteration in the Proceedings of 1 423-426 2010 Zareen Ahmad & Activity of the 7th Mohammad Antioxidant International Hayatul Islam Enzymes in Nigella Conference on sativa Seed during Hands-on Science Different Phases of Germination

Abstracts  Mohammad Hayatul islam, Iffat Zareen Ahmad and Mohammad Tariq Salman (2012):, Medicinal and pharmacological potential of Prophetic medicine, Nigella sativa, in Scientific Tribute to Country’s first Education Minister Honourable Maulana Abul Kalam Azad, 8 November, Organized by Maulana Azad National fellows & research scholars Department of Biotechnology, Integral University, Lucknow, Page No-13.

 Mohammad Hayatul Islam, Hera Choudhry, Aisha Kamal, Nida Fatima, Mohtashim Lohani and Iffat Zareen Ahmad (2013) In vitro cytotoxic effects of Nigella sativa Linn. extracts on HepG2 cell line during different germination phases , in ONCO-2013 National Conference On Advances In Cancer Research & Symposium On Cervical Cancer 12-13 February 2013, Organized by Era’s Lucknow Medical College U.P. India, Page No.27.  Hayatul Islam, I.Z.Ahmad, M.Lohani, E.Shakeel & H.Chaudhry (2012):, Anti cytogenotoxicity effect of Nigella sativa seed extract during different germination phases against carcinogenicity of benzo(a)pyrene on HepG2 cell line, in National Seminar on Plant cell, Tissue and Organ culture: Emerging Trends (Under the auspices of UGC- DRS-I Programme) 10-11 march 2012, Organized by Department of Botany, Aligarh Muslim University, Aligarh, Page No-39.

 Hayatul Islam, I.Z.Ahmad, M.T.Salman, A.Kamal & S.Parveen (2012):, Qualitative screening of phytochemical constituents in Nigella sativa seed extracts during different phases of its germination. in National Seminar on Plant cell, Tissue and Organ culture: Emerging Trends (Under the auspices of UGC-DRS-I Programme) 10-11 march 2012, Organized by Department of Botany, Aligarh Muslim University, Aligarh, Page No-40

 A. Kamal, H. Islam and I. Z. Ahmad (2010):, Hydroxyl Free Radical Scavenging Activity of Nigella Sativa L. Seed Extracts in various Germinating Stages under Cadmium Stress, In International Conference on Biological Science and Engineering (ICBE 2010), Organized by CAFET-INNOVA Technical Society (Hyderabad) and Nottingham Trent University (United Kingdom),Code AB-C 12.  Aisha Kamal, Iffat zareen Ahmad and Hayatul Islam (2010):, Effects of Cadmium Toxicity on Antioxidative Defence System of Nigella sativa in Different Phases of Seed Germination, Fourth International Conference on Plant and Environmental Pollution (ICPEP- 4, 8-10december 2010), Organized by International Society of Environmental botanist and National Botanical Research institute Lucknow India, Code SIV/P-64, Page No-94.  Aisha Kamal, Nazia farooqui, Hayatul Islam and Iffat zareen Ahmad (2011):, phytochemical studies of different phases of germination of Nigella sativa by thin layer chromatography, in National Symposium on Biodiversity and Food Security: Challenges & Devising Strategies Dec 10-11, 2011, Organized by Dheerpura Society for Advancement of Science & Rural Development and Indian Institute of Pulses Research, Kanpur.

 Hera Choudhry, Nida Fatima, Hayatul Islam and Iffat Zareen Ahmad (2013) Effect of growth regulators on the callusing response of Nigella sativa seedling, In National Seminar on Plant Sciences: New Technologies, Conservation and Environment. (Under the auspices of UGC-DRS-I Programme), 23-24 Feb, 2013, Organized by Department of Botany, Aligarh Muslim University, Aligarh (U.P.) India. Page No. 42.

Conferences/workshop/seminar  Awarded as certificate of appreciation and participation in the successful completion of proceedings of Second International Conference on''Biotechnological Advancement in Free Radical Biology and Medicine'' (ICBAFM-2017) held at Integral University, Lucknow from 23-25 January, 2017.

 Successfully completed the short term training programme on ''Molecular Modeling and Dynamics Simulation Analyses'' held at Bioinformatics Infrastructure facility (BIF), Centre of Excellence in Bioinformatics (COEBI) Department of Biochemistry, , Lucknow from November 29-30, 2016.

 Participated and presented a poster in the 3rd International Conference on “New Frontiers in Biotechnology: Science, Health & Medicine” held at Department of Biotechnology, , Bareilly on 23-24, September 2016.

 Successfully completed Hands on training Workshop in basic technique in cellular and molecular biology held at CSIR-Central Drug Research Institute (CDRI), Lucknow on 21-23, September 2016

 Participated and presented a poster in the Indo-US Workshop on ''Cell Factories'' held during 18-20 March, 2016 at IIT Bombay.

 Participated in short term course on Data Analysis/ SPSS & MINITAB from Feb 02-08, 2016 at Integral University, Lucknow. Organized by Centre of Academic Leadership and Education Management (CALEM), Under the Scheme of Pandit Madan Mohan Malaviya National Mission on Teachers and Teaching (MHRD, Govt. Of India) in collaboration with UGC Human Resource Development Centre AMU, Aligarh.

 Awarded as certificate of appreciation in the successful completion of proceedings of International Conference on''Biotechnological Advancement in Free Radical Biology and Medicine'' (ICBAFM-2015) held at Integral University, Lucknow from 14-16 November, 2015.

 articipated and presented a poster in the International Conference on “New Frontiers in Industrial and Applied Biotechnology” held at Department of Biotechnology, Invertis University, Bareilly on 18-19 September 2015.

 Attended National Conference on ‘Nanosciences, Nanotoxicology and Nanoinformatics- Present and Future Perspectives’ 14-15th March, 2015, Organized by Department of Bioengineering and Biosciences Integral University, Lucknow (U.P.).

 Attended National Conference on ‘Novel Tools and Treatment Approaches in Health Care System’ 3rd March, 2015, Organized by Faculty of Pharmacy, Integral University, Lucknow (U.P.).

 Attended a seminar on ‘Many Dimensions of Indian Atomic Energy Programme’ 25th Feb, 2015. Organized by Chhatrapati Shahu Ji Maharaj University, Kanpur in Association with Bhabha atomic Research Center, Mumbai.

 Attended a National level workshop on ‘Arm Controlled Robotics’ 11-13th Feb, 2015. Conducted by Microbotric technologies Pvt. Ltd. In Association with Integral University, Lucknow.

 Attended a National level workshop on Intellectual Property System: India Today & Tomorrow (Ist-NLW-IPSITT-2014) 10th Jan, 2014. Organized by Intellectual Property Rights Management Cell (IPRMC, CCG&D) Integral University, Lucknow in Collaboration with Intellectual Property Owners Association (IPOA) New .

 Attended a national level workshop on Computer aided drug designing (1st-NW-CADD, 2013), 9-10 November 2013. Organized by Department of Bioengineering, Integral University, Lucknow in collaboration with Department of Life-Sciences, EGICORE, Lucknow.

 Attended a national level conference on Nanoscience and Biotechnology- Present and Future Prospectives, 20th April, 2013, Organized by Department of Nanobiotechnology, Life Science Foundation of India, Karnataka and Department of Bioengineering, Integral University Lucknow at Integral University.  Attended a conference and present a research paper in ONCO-2013 National Conference On Advances In Cancer Research & Symposium On Cervical Cancer 12-13 February 2013, Organized by Era’s Lucknow Medical College U.P. India.

 International Symposium on Current Trends in Genetics and Genomics Medicines, 31st January 2013, Organized by Ram Manohar Lohiya, Institute of Medical Sciences, Lucknow.  National Level workshop on Fundamentals of Nanoscience and Biotechnology 28th – 31st January, 2013 Organized by Life Science Foundation of India, Karnataka and Department of Bioengineering, Integral university Lucknow at Integral University.  5th Science Expo 30th Jan– 3rd Feb, 2013 at Regional Science City, Lucknow.  Attended one day conference on Scientific Tribute to Country’s first Education Minister Honourable Maulana Abul Kalam Azad, 8 November 2012, Organized by Maulana Azad National fellows & research scholars Department of Biotechnology, Integral University, Lucknow.

 Attended and presented two research paper in National Seminar on Plant cell, Tissue and Organ culture: Emerging Trends (Under the auspices of UGC-DRS-I Programme) 10-11 march 2012, Organized by Department of Botany, Aligarh Muslim University, Aligarh.

 Attended presented a research paper in National Symposium on Biodiversity and Food Security: Challenges & Devising Strategies Dec 10-11, 2011, Organized by Dheerpura Society for Advancement of Science & Rural Development and Indian Institute of Pulses Research, Kanpur.

 Attended a conference and present a research paper in “In International Conference on Biological Science and Engineering (ICBE 2010)”, Organized by CAFET-INNOVA Technical Society (Hyderabad) and Nottingham Trent University (United Kingdom) on 22th august 2010 in Hyderabad (India).

Research Guiding Experience

As a Ph.D Supervisor:

S.No. Name of Student Course Title of Ph.D 1. Sabeena Arif Ph.D An alternative test system for anticancer efficacy of herbal formulations in Benzo[a]pyrene treated Cyanobacteria. 2. Firdaus Jahan Ph.D Identification and Validation of Potential Neuroprotective Secondary Metabolites From Plants for Therapeutic Application in Alzheimer’s Disease: An In Silico and In Vitro Approach

3. Rahul Kumar Ph.D PD-L1 Expression and its Association with Multiple Pandey Predictive and Prognostic Molecular Markers in Adenocarcinoma Lung

As a Supervisor of Master Degree Students Project thesis

S.No. Name of Student Course Title of Dissertation Year 1. Najnin Parveen M.Sc. Biotechnology In Vivo and In Silico Evaluation 2015 of anti-inflammatory activity of Thymoquinone and thymol.

2. Aleena Asif M.Sc. Biotechnology Antibacterial activity of 2015 Thymoquinone and thymol on clinical bacterial strains isolated from human patients.

3. Khushnuma Eram M.Sc. Biotechnology Kinetics and molecular docking 2016 study of Glimperide against Acetylcholineesterase. 4. Richa Sharma M.Sc. Biotechnology In silico study for identification of 2017 drug like inhibitors from natural compounds against InhA reductase of Mycobacterium tuberculosis. 5. Sumaiya Arshad M.Sc. Biotechnology Develpoment of novel 2017 bacteriostatic agents against chorismate mutase receptor from Mycobacterium tuberculosis using in silico techniques. 6. Neha Singh M.Sc. Biotechnology Docking study of Mycobacterium 2017 tuberculosis receptor Dpre1 with selected phytochemicals. 7. Nida Afroz M.Sc. Biotechnology Docking study on mycobacterium 2017 tuberculosis receptors Accd5 & Pks18 with selected flavonoids. 8. Arshiya Ali M.Sc. Biotechnology Effect of selected alkaloids on 2017 pantothenate kinase (Pank) from Mycobacterium tuberculosis: an in silico approach. 9. Hamda Shakeel M.Sc. Biotechnology Evaluation of inhibitory effect of 2017 terpenoids on maba receptor of Mycobacterium tuberculosis by docking study. 10. Anamta Nusrat M.Sc. Biotechnology Study of phytochemicals as a dual 2017 inhibitor of acetylcholinesterase and sodium glucose co-transporter 2: advancement in alzheimer’s disease-diabetes type 2 linkage via an enzoinformatics study. 11. Ankita Dutta M.Sc. Biotechnology Computational biological study of 2017 aromatase inhibitors docking with human placental aromatase chtochrome P450 12. Jagriti Singh M.Sc. Biotechnology Identification of drug like inhibitors 2017 from flavonoids against cyclooxygenase-2 enzyme: an in silico study. 13. Hiba Rehman M.Sc. Biotechnology Computational determination of 2017 terpenoids as lipoxygenase inhibitors by molecular docking studies. 14. Varsha Saxena M.Sc. Biotechnology Molecular docking studies of 2017 selected phytochemicals as DNA topoisomerase inhibitors. 15. Nida Firdaus M.Sc. Biotechnology Identification and validation of 2018 Neuroprotective metabolites against alzimer’s disease protein namely:Beta amyloid and Tau. 16. Adil Nehal M.Sc. Microbiology Study of cytotoxic effect of 2018 anticancer homeopathy formulations by using Cyanobacteria as a test system. 17. Mohd. Farman M.Sc. Microbiology Effect of natural compounds on the 2018 excretion of Aceylcholine esterase enzyme: A molecular approach.

Fellowship/Awards  Awarded Junior Research Fellowship (2012-14) by University Grants Commission (UGC) Govt of India Republic.  Awarded Silver Medal (2010) for being Second topper in M.Sc. (Biotechnology).  Awarded Gold Medal (2009) by Dr.Qamar Rehman (Dean of faculty Research and Development Amity International University, Lucknow) for Organizing and Presenting University Song (Tarana).  Best Poster presentation Award in National Conference On Advances In Cancer Research & Symposium On Cervical Cancer (ONCO-2013), February 2013, Organized by Era’s Lucknow Medical College U.P. India

References

Name Address of expert Prof. Mohtashim Lohani Incharge Biomedical Research Unit Jazan University, Jazan. KSA Email: [email protected] Dr. Mohd. Tariq Salman Associate Professor Department of Pharmacology University of Dammam, Dammam KSA Email ID: [email protected] Dr. Shazi Shakil Assistant Professor, Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, P.O. Box 80216 Jeddah 21589 Saudi Arabia Mobile: 00966581491176 Email: [email protected]; [email protected]

Date: 15-04-2018 Place: Lucknow Dr. Mohammad Hayatul Islam