Sexual Anatomy and Function in Women with and Without Genital Mutilation: a Cross-Sectional Study
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FEMALE SEXUAL FUNCTION Sexual Anatomy and Function in Women With and Without Genital Mutilation: A Cross-Sectional Study Jasmine Abdulcadir, MD,1,2 Diomidis Botsikas, MD,1,3 Mylène Bolmont, PhD Candidate,4 Aline Bilancioni, RN,1 Dahila Amal Djema, MD,3 Francesco Bianchi Demicheli, MD,1 Michal Yaron, MD,1 and Patrick Petignat, MD1 ABSTRACT Introduction: Female genital mutilation (FGM), the partial or total removal of the external genitalia for non-medical reasons, can affect female sexuality. However, only few studies are available, and these have significant methodologic limitations. Aim: To understand the impact of FGM on the anatomy of the clitoris and bulbs using magnetic resonance imaging and on sexuality using psychometric instruments and to study whether differences in anatomy after FGM correlate with differences in sexual function, desire, and body image. Methods: A cross-sectional study on sexual function and sexual anatomy was performed in women with and without FGM. Fifteen women with FGM involving cutting of the clitoris and 15 uncut women as a control group matched by age and parity were prospectively recruited. Participants underwent pelvic magnetic resonance imaging with vaginal opacification by ultrasound gel and completed validated questionnaires on desire (Sexual Desire Inventory), body image (Questionnaire d’Image Corporelle [Body Image Satisfaction Scale]), and sexual function (Female Sexual Function Index). Main Outcome Measures: Primary outcomes were clitoral and bulbar measurements on magnetic resonance images. Secondary outcomes were sexual function, desire, and body image scores. Results: Women with FGM did not have significantly decreased clitoral glans width and body length but did have significantly smaller volume of the clitoris plus bulbs. They scored significantly lower on sexual function and desire than women without FGM. They did not score lower on Female Sexual Function Index sub-scores for orgasm, desire, and satisfaction and on the Questionnaire d’Image Corporelle but did report significantly more dyspareunia. A larger total volume of clitoris and bulbs did not correlate with higher Female Sexual Function Index and Sexual Desire Inventory scores in women with FGM compared with uncut women who had larger total volume that correlated with higher scores. Conclusion: Women with FGM have sexual erectile tissues for sexual arousal, orgasm, and pleasure. Women with sexual dysfunction should be appropriately counseled and treated. J Sex Med 2016;13:226e237. Copyright Ó 2016, International Society for Sexual Medicine. Published by Elsevier Inc. All rights reserved. Key Words: Female Genital Mutilation; Female Genital Cutting; Female Genital Mutilation/Cutting; Clitoris; Clitoral Reconstruction; Sexual Function/Dysfunction; Clitoral Size INTRODUCTION Received August 24, 2015. Accepted December 6, 2015. Female genital mutilation (FGM) involves the partial or total 1Department of Obstetrics and Gynecology, Geneva University Hospitals, removal of the external genitalia or other injury to female genital 1 Geneva, Switzerland; organs for non-medical reasons. The practice of FGM exists in 2Faculty of Medicine, University of Geneva, Geneva, Switzerland; Africa, Asia, the Middle East, South America, and Western 1 3Division of Radiology, Department of Imaging, Geneva University Hospitals, countries. FGM is classified into four types by the World Geneva, Switzerland; Health Organization (WHO) and can involve cutting of the 4Faculty of Psychology and Educational Science, University of Geneva, clitoris,1 the principal organ of female sexual pleasure.2 Geneva, Switzerland FGM can cause long-term health consequences.3,4 However, Copyright ª 2016, International Society for Sexual Medicine. Published by Elsevier Inc. All rights reserved. the impact of FGM on sexuality remains unclear because only http://dx.doi.org/10.1016/j.jsxm.2015.12.023 few studies are available and these include methodologic 226 J Sex Med 2016;13:226e237 Female Sexual Anatomy and Function With and Without Genital Mutilation 227 limitations.5,6 Current evidence does not focus on the different cutting, then the woman would develop lethal or very severe consequences and types of FGM, on cutting of the clitoris,5 or complications. Other sexually responsive tissues of the vulva are on the fact that female sexual development and sexuality depend the vascular tissue immediately beneath the epithelium of the on complex interactions among anatomic, biochemical, neuro- labia minora (distinct from the bulbs) and the spongy tissue physiological, cognitive, cultural, and socio-contextual factors.7 around the urethral lumen, called the corpus spongiosum of the Women with FGM have specific anatomic and sociocultural urethra.14,15 FGM types II and III involve cutting of the labia issues. In addition, they are more likely to have had other minora and can damage its vascular tissue. FGM complications traumatic experiences that can affect their sexuality, such as include lesions of the urethral meatus but these do not require forced marriage or rape.8 the removal of vascular tissue around the urethra. Several beliefs linked to the presence of a clitoris to a woman’s Because most erectile structures are not excised, healthy sexuality exist in the West and in countries where FGM is women with FGM who are devoid of long-term complications traditionally practiced and are held by caregivers.9 Removal of can reach orgasm and experience satisfying sexual e the clitoris is believed to decrease or eliminate sexual pleasure, relationships.6,12 14,17 Furthermore, because most of the clitoris arousal, and orgasm, which is the leading reason for the practice remains, the clitoral stump beneath the scar tissue can be re- of FGM.1 Many caregivers believe that sexual dysfunction in exposed by a procedure known as clitoral reconstruction.16 women with FGM results from the absence of sexual organs, for Currently, the effectiveness and safety of a such technique is which no treatment is available.9,10 Even the WHO classification debated and conclusive evidence is lacking.18 The surgery is re- of FGM misleadingly reports that some forms of FGM involve ported to improve sexual function16 because it seems to decrease total removal of the clitoris.1 However, anatomically, it is the clitoral pain by removing peri-clitoral fibrosis, thus making the visible part of the clitoris (the glans) that is cut. The crura and clitoris more accessible to stimulation. However, many women part of the body of the clitoris remain intact under the scar.11,12 request clitoral reconstruction to improve their female identity The clitoris is a multiplanar organ with a boomerang shape. It and genital image, despite having an already functional clitoral 16 is composed of the glans (the only external, clinically visible stump. In these cases, sexual function could be improved by fi portion of the clitoris, covered by the prepuce), the body (con- enhanced body image, female identity, and self-con dence, nected to the pubic symphysis by the suspensory ligament of the rather than by a more accessible clitoris. The effects of psycho- clitoris), and the crura (two deep stems attached to the ischio- sexual and multidisciplinary care (alone or in association with pubic rami; Figure 1). The bulbs are two other female erectile surgery) need to be studied because they are safer and sometimes 18,19 structures that become engorged during arousal (Figure 1) and could be more effective than clitoral surgery alone. are beneath the labia.2,13 FGM can involve cutting of the labia Further scientific investigations regarding sexual anatomy, minora or majora (type II or III)1 and could put these structures development, and function in women with FGM are required to at risk. However, the bulbs are covered by the superficial perineal eradicate existing myths and misconceptions and would allow fascia and the bulbocavernosus muscles.2 If reached by deep offering the best available medical, surgical, and psychosexual care for complications after FGM. In uncut women, the visible part of the female erectile organs is the glans of the clitoris. In women with FGM that involves cutting of the clitoris, the clitoral stump is buried under a scar and can be palpated. Because most female sexual organs cannot be directly observed, pelvic magnetic resonance imaging (MRI) has been used e to investigate the anatomy of the clitoris and bulbs20 22 and its e relation to sexual function in women without FGM.23 26 AIMS One aim was to study the impact of FGM on (i) the anatomy of the clitoris and bulbs using MRI and (ii) sexual function using Figure 1. Clitoral and bulbar anatomy in relation to the sur- psychometric instruments. Another aim was to investigate fi rounding super cial anatomic structures. The clitoris is composed whether differences in the anatomy of women after FGM of the glans (visible portion of the clitoris covered by the prepuce), the body (connected to the pubic symphysis by the suspensory correlate with differences in sexual function. ligament of the clitoris), and the crura (the two deep stems attached to the ischiopubic rami). The bulbs are the other two METHODS erectile structures that are beneath the labia. They are covered by the bulbocavernosus muscles. Reprinted with permission from This was a cross-sectional study of sexual anatomy and func- Pauls,13 copyright John Wiley and Sons. Figure 1 is available in color tion in women with and without FGM. All participants signed at www.jsm.jsexmed.org. an informed consent form to undergo pelvic