Journal Pre-proof COVID-19 vaccines Duduzile Ndwandwe, Charles S Wiysonge PII: S0952-7915(21)00090-X DOI: https://doi.org/10.1016/j.coi.2021.07.003 Reference: COIMMU 2121 To appear in: Current Opinion in Immunology Please cite this article as: Ndwandwe D, Wiysonge CS, COVID-19 vaccines, Current Opinion in Immunology (2021), doi: https://doi.org/10.1016/j.coi.2021.07.003 This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. © 2020 Published by Elsevier. COVID-19 vaccines Duduzile Ndwandwe1* and Charles S Wiysonge1,2,3 1 Cochrane South Africa, South African Medical Research Council, Parow Valley, 7501, Cape Town, South Africa 2 Division of Epidemiology and Biostatistics, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, 7505, Cape Town, South Africa; 3 School of Public Health and Family Medicine, Faculty of Health Sciences, University of Cape Town, Observatory, 7925, Cape Town, South Africa. *corresponding author Dr Duduzile Ndwandwe E-mail:
[email protected] Tel: +27 21 938 0222 Journal Pre-proof Highlights COVID-19 vaccine development has accelerated at an incredible rate with 105 vaccines in clinical development and 18 approved for emergency use within 12-18 months of the virus being sequenced.