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Bronchiolitis BRONCHIOLITIS DEFINITION: Bronchiolitis is a viral infection, usually seen in the winter months, which causes infants and small children to wheeze and cough. It is often caused by the Respiratory Syncitial Virus, or RSV. Because of its viral nature, antibiotics will not cure it. EXPECTED COURSE: Bronchiolitis usually starts out with a runny nose and/or mild cough. The virus then causes swelling and inflammation in the smallest of the bronchial tubes, called bronchioles. This results in wheezing, rapid breathing, and a tight cough. As the symptoms progress into the chest, there may be a fever. Over the next several days, as the swelling goes down in the bronchioles, the phlegm starts to collect in them. The wheezing becomes more rattly; the cough becomes looser and more productive. The babies will often choke on, or vomit the mucus at this stage. Finally, over the next several days, all the phlegm comes up. Eventually, the lungs clear, and the cough and wheezing subsides. The children are back to normal in two to three weeks. Most babies remain relatively perky throughout this course of events. Some of the children do get more ill however, and may need to be hospitalized. HOME TREATMENT: Treatment is aimed at relieving symptoms and is not curative. • Offer plenty of fluids, preferably clear liquids. The baby's appetite may be down for a few days. • You may give acetaminophen (eg Tylenol) for fever if the child is over 2 months old. • A humidifier may help some of the nasal and the chest congestion. • Chest percussion: Place the baby face down over your knees, with his head slightly lower than his behind. Cup your hands and gently pound on his back on either side of his backbone, above his waist. This will help to vibrate loose the mucus that is in his bronchial tubes, which he may cough and swallow, or vomit. • The doctor may prescribe a medication aimed at dilating the bronchial tubes. In some cases this may help; in others it may not be very helpful and just cause side effects. Antibiotics may be prescribed if the baby has an associated bacterial infection, such as an ear infection. Bronchiolitis is contagious like the common cold. It is primarily an illness of children under the age of two. Babies may get bronchiolitis more than once, however. Repeated episodes of bronchiolitis, or those cases that occur in the summertime, or over the age of two years repeatedly, may be associated with the later development of asthma. CALL OUR OFFICE IMMEDIATELY if: • Your child is not taking fluids well enough to soak a diaper every 6-8 hours. • Her color is not good. (e.g. the baby turns purple with cry or is unusually pale in the lips, or gray). • He has significantly decreased activity (true “lethargy” or difficulty arousing) or is very irritable. • Fever is greater than 101.5°F lasting over 72 hours, or any fever greater than 100.3°F rectally if your child is under 2 months of age. • Breathing becomes more labored and difficult. Take the shirt off to observe breathing while the child is at rest. Call if you observe the following: o Retractions (caving in above the collarbone, between the ribs or below the ribcage). o Grunting or flaring (widening) of the nostrils with each breath. o Rapid breathing at rest: Count breaths taken in 60 seconds. Call if your child’s breathing is: • Greater than 60 if <6 months • Greater than 50 if 6-12 months • Greater than 40 if 1-3 years During regular hours if: •A fever lasts more than 3 days and the baby is over 2 months old. •The cough lasts more than 3 weeks. •You have other concerns or questions. (Revised 4/07) 2 of 2 .
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  • Bronchiolitis
    BRONCHIOLITIS During breathing, air travels first through the nose or mouth, then through the voicebox (larynx), the windpipe (trachea), the bronchi, the bronchioles, and finally into the lungs. These airways become progressively smaller as the lung is approached. The bronchioles are the smallest of the airways. Children that develop bronchiolitis have a viral infection of these small airways. The virus often also infects the upper respiratory system producing the common cold symptoms: runny nose, congestion, fever, and cough. What distinguishes bronchiolitis from the common cold is the inflammation in the bronchioles, which causes wheezing. Wheezing is a musical noise made during expiration (breathing out). It is caused by a narrowing of the bronchioles. This narrowing is caused by bronchial tube muscle spasm, swelling of the lining of the bronchiole, and excess mucous production in the bronchiole. This is very similar to the problem in older children that have asthma. Bronchiolitis is common in the wintertime and usually affects children less than two years old. It is most often caused by a virus called RSV (respiratory syncitial virus), but can occasionally be caused by influenza or other "cold" viruses. It is a mystery why some children infected with the virus have only a common head cold while others develop the wheezing of bronchiolitis. One theory is that these children have allergic tendencies and are demonstrating an "allergic reaction" to the virus. This may explain why infants who develop bronchiolitis often have problems with asthma in later life. Treatment: Similar to other viral infections, there is no simple "cure" for bronchiolitis. The child's own immune system will produce antibodies to kill the virus.
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  • Respiratory Syncytial Virus Bronchiolitis in Children DUSTIN K
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  • Bronchiolitis (RSV)
    Bronchiolitis (RSV) Bronchiolitis (bron-key-oh-LIE-tiss) is an infection of the small airways caused by a virus. The most common viruses that cause it are RSV (respiratory syncytial virus), para influenza virus, rhinovirus (common cold), human metapneumovirus and adenovirus. Health care providers often call bronchiolitis "RSV infection." Bronchiolitis is seen most often in late fall and winter months through March. Bronchiolitis affects the small airways (bronchioles) in the lower respiratory tract (Picture 1). These small airways become swollen and filled with mucus and tiny cell particles. The narrow airways make it hard for the child to breathe out. This illness usually affects infants between the ages of 2 and 12 months. It is rare in children over 2 years of age; however, older children and adults can get cold-like symptoms caused by the same virus. Early Signs of Bronchiolitis . Runny nose and stuffiness . Fever is possible . Coughing (lasts about 3 to 4 weeks) . Irritability Later Signs . Fast and shallow breathing . Chest may pull in when your child breathes (retractions). This happens because he or she cannot move air in and out of the lungs. Wheezing with long and noisy breathing out. Wheezing and tight breathing get worse for 2 to 3 days, then start to get better. Wheezing lasts about for 7 days. Frequent coughing spells . Less interest in eating Picture 1 The respiratory system inside the body. Not as playful; gets tired easily HH-I-31 8/85, Revised 11/15 Copyright 1985, Nationwide Children's Hospital Bronchiolitis Page 2 of 3 What to Expect at the Doctor's Office or Emergency Room .
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  • Asthma Exacerbation Management
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  • Obliterative Bronchiolitis, Cryptogenic Organising Pneumonitis and Bronchiolitis Obliterans Organizing Pneumonia: Three Names for Two Different Conditions
    Eur Reaplr J EDITORIAL 1991, 4, 774-775 Obliterative bronchiolitis, cryptogenic organising pneumonitis and bronchiolitis obliterans organizing pneumonia: three names for two different conditions R.M. du Bois, O.M. Geddes Over the last five years, increasing confusion has has been applied to conditions in which airflow obstruc­ developed over the use of the terms "bronchiolitis tion is prominent and in which response to treatment is obliterans" and "bronchiolitis obliterans organizing poor. pneumonia". The confusion stems largely from the common use of the term "bronchiolitis obliterans" or "obliterative bronchiolitis" in the diagnostic labels applied "Cryptogenic organizing pneumonitis" or "bronchi· to two entities which are quite distinct clinically but which otitis obliterans organizing pneumonia" (BOOP) bear certain resemblances histologically. Cryptogenic organizing pneumonitis was first described by DAVISON et al. [7] in 1983. The clinical syndrome ObUterative bronchiolitis consisted of breathlessness, malaise, fever, high erythrocyte sedimentation rate (ESR), pneumonic In 1977, GEODES et al. [1] reported the case histories shadowing on chest radiograph with a restrictive of six patients whose clinical condition was characterized pulmonary function defect and low gas transfer coeffi­ by airways obliteration in association with rheumatoid cient. On histological examination of lung biopsy mate· arthritis. The striking clinical features were of rapidly rial, the typical and distinguishing feature was the progressive breathlessness and the fmding on examination presence of connective tissue within the alveoli, alveolar of a high-pitched mid-inspiratory squeak heard over the ducts and, occasionally, in respiratory bronchioles. This lung fields. Chest radiographs showed hyperinflated lungs connective tissue consisted of "loosely woven fibres of but were otherwise normal.
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  • Bronchiolitis
    Bronchiolitis What is bronchiolitis? Bronchiolitis is a viral infection of the lungs that usually affects infants. There is swelling in the smaller airways or bronchioles of the lung, which causes coughing and wheezing. Bronchiolitis is the most common reason for children under 1 year old to be admitted to the hospital. What are the symptoms of bronchiolitis? The following are the most common symptoms of bronchiolitis. However, each child may experience symptoms differently. Symptoms may include: Runny nose or nasal congestion Fever Cough Changes in breathing patterns (wheezing and breathing faster or harder are common) Decreased appetite Fussiness Vomiting What causes bronchiolitis? Bronchiolitis is a common illness caused by different viruses. The most common virus causing this infection is Respiratory Syncytial Virus (RSV). However, many other viruses can cause bronchiolitis including: Influenza, Parainfluenza, Rhinovirus, Adenovirus, and Human metapneumovirus. Initially, the virus causes an infection in the upper airways, and then spreads downward into the lower airways of the lungs. The virus causes swelling of the airways. Mucus is also produced in the airways. This narrowing of the airways can make it difficult for your child to breath, eat, or nurse. How is bronchiolitis diagnosed? Bronchiolitis is usually diagnosed on the history and physical examination of the child. Antibiotics are not helpful in treating viruses and are not needed to treat bronchiolitis. Because there is no cure for the disease, the goal of treatment is to make your child comfortable and to support their symptoms. This treatment may include suctioning to keep the airways clear, extra oxygen if the blood oxygen levels are low, or hydration if your child is not able to feed well.
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  • Bronchitis, Acute Chest Cold/ Bronchiolitis
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  • BRONCHIOLITIS Maud Meates-Dennis
    BEST PRACTICE Arch Dis Child Educ Pract Ed: first published as 10.1136/adc.2004.067660 on 21 November 2005. Downloaded from BRONCHIOLITIS Maud Meates-Dennis ep81 Arch Dis Child Educ Pract Ed 2005;90:ep81–ep86. doi: 10.1136/adc.2004.067660 iral bronchiolitis is a common worldwide disease of infants and young children. It is a significant cause of hospitalisation in infancy. In the year 2002–3, 0.1% of all hospital bed Vdays in England were for acute bronchiolitis with a mean length of stay of 2.7 days,1 and in a study in one UK region the incidence of bronchiolitic related admission was 30.8 per 1000 infants.2 PATHOPHYSIOLOGY The underlying pathophysiology is inflammation of the small airways (bronchioles). Infection of the bronchiolar and ciliated epithelial cells produces increased mucous secretion, cell death and sloughing, followed by a peribronchiolar lymphocytic infiltrate and submucousal oedema.3 This combination of debris and oedema results in distal airway obstruction. During expiration, the additional dynamic narrowing produces disproportionate airflow decrease and air trapping. The effort of breathing is increased due to increased end expiratory lung volume and decreased lung compliance.3 Recovery of pulmonary epithelial cells occurs after 3–4 days, but cilia do not regenerate for approximately two weeks.3 The debris is cleared by macrophages. EPIDEMIOLOGY Fifty to ninety per cent of bronchiolitis is caused by respiratory syncitial virus (RSV) infection.4 RSV is a negative-sense, enveloped RNA virus that is unstable in the environment, surviving only a few hours on environmental surfaces. RSV is spread from respiratory secretions through close copyright.
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  • Respiratory Tract Infections Pediatric Treatment Recommendations
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  • Bronchiolitis
    BRONCHIOLITIS What is bronchiolitis? Bronchiolitis is a viral infection that happens mostly in the late fall and winter. It causes the small breathing tubes in the lungs to become tight, swollen and filled with mucous. This can make it harder for air to move in and out of the lungs. Bronchiolitis happens most often in children under one year of age, and is the most common reason why babies are admitted to hospital. What causes bronchiolitis? Bronchiolitis is often caused by a virus called RSV (respiratory syncytial virus). It’s easy to catch and spreads by coughs, sneezes or objects that have been touched by a sick person (like toys, computer keyboards or hands). This virus can get into our bodies through our mouths, noses or eyes. How do I know if my child has bronchiolitis? If your child has bronchiolitis, they will have: • a stuffy or runny nose • wheezing (whistling sound coming from the • a cough (sometimes a tight cough) chest) These symptoms can last for 2-3 weeks. Children may also have a fever or have trouble breathing. Caring for your child at home Sometimes the infection is more serious, and the child must stay in hospital. If your baby was born too early (premature) or if they have heart or lung problems, they may have to be cared for in hospital. Most of the time, you can take care of your child at home. 1. Give your child extra fluids: breast milk, formula, water or juice (babies over four months of age can have apple juice). Feeding may be tiring for your baby or child, so try feeding smaller amounts more often.
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  • Bronchiolitis
    Children’s Health Queensland Hospital and Health Service fact sheet Emergency Department Bronchiolitis Bronchiolitis is a common condition of the small In hospital the treatment of bronchiolitis may include airways (breathing tubes) affecting children under oxygen therapy and suctioning of the nose. If your child the age of two years. has difficulties feeding they may be given fluids through More than 80 per cent of cases occur in the first a nasogastric tube (via the nose into the stomach) or year of life, commonly between 2 to 10 months of intravenous line (into the vein). age. It is more common in winter. Things you can do at home What causes bronchiolitis? Bronchiolitis is an infectious disease so try to keep your Bronchiolitis is caused by a virus. The most common virus is ■ child away from other small children and babies until respiratory syncytial virus (RSV). Children normally contract they recover. the virus from another family member suffering from a ■ Keep your child away from cigarette smoke. mild respiratory infection (cold or flu symptoms). The virus Ensure your child is getting enough fluid. Smaller, more attacks the small breathing tubes (bronchioles) of the ■ frequent feeds may be easier for your child. lungs. ■ Keep your baby’s nose clear by cleaning with tissues or cotton buds (as small babies only breathe through their Signs and symptoms nose). ■ Bronchiolitis often starts with ‘cold’ symptoms (runny ■ A small bit of salt water solution (eg. Narium or Fess) nose, cough, sneezing, sometimes fever) may be dropped or sprayed in each nostril before your ■ Over a period of a few days, coughing worsens and you baby’s feed to help clear the nose.
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  • A Case of Cryptogenic Organizing Pneumonia in a Patient with Idiopathic Thrombocytopenic Purpura
    J Case Rep Images Med 2017;3:39–41. De Giorgi et al. 39 www.edoriumjournals.com/case-reports/jcrm CASE REPORT PEER REVIEWED OPEN| OPEN ACCESS ACCESS A case of cryptogenic organizing pneumonia in a patient with idiopathic thrombocytopenic purpura Alfredo De Giorgi, Marco Fiore, Federico Moro, Michele Domenico Spampinato, Fabio Fabbian ABSTRACT with corticosteroids obtaining progressive improvement of thrombocytopenia and Introduction: Cryptogenic organized pulmonary distress. Conclusion: Association pneumonia (COP) or bronchiolitis obliterans- between ITP and COP or BOOP could be ascribed organizing pneumonia (BOOP) is clinical to autoimmune derangement. Respiratory condition characterized by interstitial lung symptoms and imaging in patients with ITP disease with loss of functioning parenchyma could suggest association with COP or BOOP. due to inflammatory damage and pulmonary However, both conditions might ameliorate fibrosis. We report a case of COP related with corticosteroid treatment. to autoimmune condition in patients with idiopathic thrombocytopenic purpura (ITP) Keywords: Atoll sign, Bronchiolitis obliterans-or- and diabetes mellitus type 1. Case Report: A ganizing pneumonia, Cryptogenic organized pneu- 46-year-old deaf and mute male was admitted monia, Idiopathic thrombocytopenic purpura to our hospital for general sickness, severe dyspnea. He had a history of ITP started 20 How to cite this article years before, previous splenectomy, smoking, systemic hypertension, diabetes mellitus De Giorgi A, Fiore M, Moro F, Spampinato MD, type 1, glaucoma, previous admission for Fabbian F. A case of cryptogenic organizing pulmonary thromboembolism. High resolution pneumonia in a patient with idiopathic computed tomography (HRCT) found diffuse thrombocytopenic purpura. J Case Rep Images Med interstitial thickening with a bilateral ground- 2017;3:39–41.
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