CHAPTER 114 Factitious Disorders and Malingering Jag S

Total Page:16

File Type:pdf, Size:1020Kb

CHAPTER 114 Factitious Disorders and Malingering Jag S CHAPTER 114 Factitious Disorders and Malingering Jag S. Heer 14,16 PERSPECTIVE children. Other names applied include Polle’s syndrome (Polle was a child of Baron Munchausen who died mysteriously),3,10 fac- Patients may present to the emergency department with symp- titious disorder by proxy,17 pediatric condition falsification,18 and toms that are simulated or intentionally produced. The reasons Meadow’s syndrome.2 that cause this behavior define two distinct varieties: factitious Malingering is the simulation of disease by the intentional pro- disorders and malingering. duction of false or grossly exaggerated physical or psychological Factitious disorders are characterized by symptoms or signs that symptoms, motivated by external incentives, such as avoidance of are intentionally produced or feigned by the patient in the absence military conscription or duty, avoidance of work, obtainment of of apparent external incentives.1,2 Factitious disorders have been financial compensation, evasion of criminal prosecution, obtain- present throughout history. In the second century, Galen described ment of drugs, gaining of hospital admission (for the purpose of Roman patients inducing and feigning vomiting and rectal bleed- obtaining free room and board), or securing of better living condi- ing.3 Hector Gavin sought to categorize this behavior in 1834.3 tions.2,19-21 The most common goal among such “patients” present- These patients constitute approximately 1% of general psychiatric ing to the emergency department is to obtain drugs, whereas in referrals, but this percentage is lower than that seen in emergency the office or clinic the gain is more commonly insurance payments medicine because these patients rarely accept psychiatric treat- or industrial injury settlements.22 Because of underreporting the ment.1,4 Of patients referred to infectious disease specialists for true incidence of malingering is difficult to gauge, but estimates fever of unknown origin, 9.3% of the disorders are factitious.5 include a 1% incidence among mental health patients in civilian Between 5 and 20% of patients observed in epilepsy clinics have clinical practice, 5% in the military, and as high as 10 to 20% psychogenic seizures, and the number reaches 44% in some among patients presenting in a litigious context.20 The most likely primary care settings.6 Among patients submitting kidney stones conditions to be feigned are mild head injury, fibromyalgia, for analysis, up to 3.5% are fraudulent.7 chronic fatigue syndrome, and chronic pain.23 Munchausen syndrome, the most dramatic and exasperating of the factitious disorders, was originally described in 1951.8 This fortunately rare syndrome takes its name from Baron Karl F. von CLINICAL FEATURES Munchausen (1720-1797), a revered German military officer and Factitious Disorders noted raconteur who had his embellished life stories stolen and parodied in a 1785 pamphlet.3 The diagnosis applies to only 10 to With a factitious disorder, the production of symptoms and signs 20% of patients with factitious disorders.1,9 Other names applied is compulsive; the patient is unable to refrain from the behavior include the “hospital hobo syndrome” (patients wander from hos- even when its risks are known. The behavior is voluntary only in pital to hospital seeking admission), peregrinating (wandering) the sense that it is deliberate and purposeful (intentional) but not problem patients, hospital addict, polysurgical addiction, laparo- in the sense that the acts can be fully controlled.2 The underlying tomaphilia migrans, Kopenickades syndrome, Ahasuerus syn- motivation for producing these deceptions, securing the sick role, drome, and hospital vagrant.4,10,11 is primarily unconscious.9,24,25 Individuals who readily admit that Munchausen syndrome by proxy (MSBP), an especially perni- they have produced their own injuries (e.g., self-mutilation) are cious variant that involves the simulation or production of facti- not included in the category of factitious disorders.17 Presenta- tious disease in children by a parent or caregiver, was first described tions may be acute, in response to an identifiable recent psycho- in 1977.12 There are approximately 1200 estimated new cases of social stress (termination of romantic relationship, threats to MSBP per year in the United States.3 The condition excludes self-esteem), or a chronic life pattern, reflective of the way in straightforward physical abuse or neglect and simple failure to which the person deals with life in general.26 The symptoms thrive; mere lying to cover up physical abuse is not MSBP.13,14 The involved may be either psychological or physical. key discriminator is motive: the mother is making the child ill so that she can vicariously assume the sick role with all its benefits. Psychological Symptoms The mortality rate from MSBP is 9 to 31%.14,15 Children who die are generally younger than 3 years, and the most frequent causes This disorder is the intentional production or feigning of psycho- of death are suffocation and poisoning.14 Permanent disfigure- logical (often psychotic) symptoms suggestive of a mental disor- ment or permanent impairment of function resulting directly der. Stimulants may be used to induce restlessness or insomnia; from induced disease or indirectly from invasive procedures, mul- hallucinogens, to create altered levels of consciousness; and hyp- tiple medications, or major surgery occurs in at least 8% of these notics, to produce lethargy. This psychological factitious condition 1487 1488 PART III ◆ Medicine and Surgery / Section Eight • Psychiatric and Behavioral Disorders is less common than factitious disorders with physical symptoms The symptoms presented are “limited only by the person’s and is almost always superimposed on a severe personality medical knowledge, sophistication, and imagination.”2 The alleged disorder.2,17 illnesses involved have been termed dilemma diagnoses in that investigators rarely can totally rule out the disorder, clarify the 4 Physical Symptoms cause, or prove that it did not exist at one time. Common pre- sentations are those that most reliably result in admission to the The intentional production of physical symptoms may take the hospital, such as abdominal pain, self-injection of a foreign sub- form of fabricating of symptoms without signs (e.g., feigning stance,10,11 feculent urine, bleeding disorders, hemoptysis, parox- abdominal pain), simulation of signs suggesting illness (e.g., ysmal headaches, seizures, shortness of breath, asthma with fraudulent pyuria, induced anemia), self-inflicted conditions (e.g., respiratory failure,4,33 chronic pain,25 acute cardiovascular symp- the production of abscesses by injection of contaminated material toms (e.g., chest pain, induced hypertension and syncope),32 renal under the skin), or genuine complications from the intentional colic and spurious urolithiasis,7 fever of unknown origin (hyper- misuse of medications (e.g., diuretics, hypoglycemic agents).21 pyrexia figmentatica),5,11 profound hypoglycemia, and coma with These patients are predominantly unmarried women younger anisocoria.34 Some self-induced conditions are highly injurious or than 40 years. They typically accept their illness with few com- even lethal.10 plaints and are generally well-educated, responsible workers or The patient usually presents during evenings or on weekends so students with moral attitudes and otherwise conscientious behav- as to minimize accessibility to psychiatric consultants, personal ior.21,27,28 Many are in health care occupations, including nurses, physicians, and past medical records.11,27 In teaching institutions aides, and physicians. these patients often present in July, shortly after the change in These patients are willing to undergo incredible hardship, limb resident house officers.4 They relate their history in a precise, amputation, organ loss, and even death to perpetuate the mas- dramatic, even intriguing fashion, embellished with flourishes of querade.21 Although multiple hospitalizations often lead to iatro- pathologic lying and self-aggrandizement. Pseudologia fantastica, genic physical conditions, such as postoperative pain syndromes or pathologic lying, is a distinctive peculiarity of these patients. In and drug addictions, patients continue to crave hospitalization a chronic, often lifelong behavior pattern, the patient typically for its own sake. They typically have a fragile and fragmented takes a central and heroic role in these tales, which may function self-image and are susceptible to psychotic and even suicidal epi- as a way to act out fantasy.35 The history quickly becomes vague sodes.27 Interactions with the health care system and relationships and inconsistent, however, when the patient is questioned in detail with caregivers provide the needed structure that stabilizes the about medical contacts.2,29 Attempts to manage the complaint on patient’s sense of self. The hospital may be perceived as a refuge, an outpatient basis are adamantly resisted.25 Once admitted, the sanctuary, or womblike environment.4,21,24,29 Some patients are patient initially appeals to the physician’s qualities of nurturance apparently driven by the conviction that they have a real but as and omnipotence, lavishing praise on the caregivers. Behavior yet undiscovered illness. Consequently, artificial symptoms are rapidly evolves, however, as the patient creates havoc on the ward contrived to convince the physician to continue a search for the by insisting on excessive attention
Recommended publications
  • The Diagnosis of Ganser Syndrome in the Practice of Forensic Psychology
    Drob, S., & Meehan, K. (2000). The diagnosis of Ganser Syndrome in the practice of forensic psychology. American Journal of Forensic Psychology, 18(3), 37-62. The Diagnosis of Ganser Syndrome in the Practice of Forensic Psychology Sanford L. Drob, Ph.D. and Kevin Meehan Forensic Psychiatry Service, New York University—Bellevue Medical Center The authors gratefully acknowledge the contributions of Robert H. Berger, M.D., Alexander Bardey, M.D., David Trachtenberg, M.D., Ruth Jonas, Ph.D. and Arthur Zitrin, M.D. for their assistance in helping to formulate the case example presented herein. 1 Drob, S., & Meehan, K. (2000). The diagnosis of Ganser Syndrome in the practice of forensic psychology. American Journal of Forensic Psychology, 18(3), 37-62. Abstract Ganser syndrome, which is briefly described as a Dissociative Disorder NOS in the DSM-IV is a poorly understood and often overlooked clinical phenomenon. The authors review the literature on Ganser syndrome, offer proposed screening criteria, and propose a model for distinguishing Ganser syndrome from malingering. The “SHAM LIDO” model urges clinicians to pay close attention to Subtle symptoms, History of dissociation, Abuse in childhood, Motivation to malinger, Lying and manipulation, Injury to the brain, Diagnostic testing, and longitudinal Observations, in the assessment of forensic cases that present with approximate answers, pseudo-dementia, and absurd psychiatric symptoms. A case example illustrating the application of this model is provided. 2 Drob, S., & Meehan, K. (2000). The diagnosis of Ganser Syndrome in the practice of forensic psychology. American Journal of Forensic Psychology, 18(3), 37-62. In this paper we propose a model for diagnosing the Ganser syndrome and related dissociative/hysterical presentations and evaluating this syndrome in connection with forensic assessments.
    [Show full text]
  • Psychogenic Nonepileptic Seizures: Diagnostic Challenges and Treatment Dilemmas Taoufik Alsaadi1* and Tarek M Shahrour2
    Alsaadi and Shahrour. Int J Neurol Neurother 2015, 2:1 International Journal of DOI: 10.23937/2378-3001/2/1/1020 Volume 2 | Issue 1 Neurology and Neurotherapy ISSN: 2378-3001 Review Article: Open Access Psychogenic Nonepileptic Seizures: Diagnostic Challenges and Treatment Dilemmas Taoufik Alsaadi1* and Tarek M Shahrour2 1Department of Neurology, Sheikh Khalifa Medical City, UAE 2Department of Psychiatry, Sheikh Khalifa Medical City, UAE *Corresponding author: Taoufik Alsaadi, Department of Neurology, Sheikh Khalifa Medical City, UAE, E-mail: [email protected] They are thought to be a form of physical manifestation of psychological Abstract distress. Psychogenic Non-Epileptic Seizures (PNES) are grouped in Psychogenic Nonepileptic Seizures (PNES) are episodes of the category of psycho-neurologic illnesses like other conversion and movement, sensation or behavior changes similar to epileptic somatization disorders, in which symptoms are psychological in origin seizures but without neurological origin. They are somatic but neurologic in expression [4]. The purpose of this review is to shed manifestations of psychological distress. Patients with PNES are often misdiagnosed and treated for epilepsy for years, resulting in light on this common, but, often times, misdiagnosed problem. It has significant morbidity. Video-EEG monitoring is the gold standard for been estimated that approximately 20 to 30% of patients referred to diagnosis. Five to ten percent of outpatient epilepsy populations and epilepsy centers have PNES [5]. Still, it takes an average of 7 years before 20 to 40 percent of inpatient and specialty epilepsy center patients accurate diagnosis and appropriate referral is made [6]. Early recognition have PNES. These patients inevitably have comorbid psychiatric and appropriate treatment can prevent significant iatrogenic harm, and illnesses, most commonly depression, Post-Traumatic Stress Disorder (PTSD), other dissociative and somatoform disorders, may result in a better outcome.
    [Show full text]
  • Validity Assessment in Traumatic Brain Injury Impairment and Disability Evaluations
    Validity Assessment in Traumatic Brain Injury Impairment and Disability Evaluations a,b,c,d, Nathan D. Zasler, MD, DABPMR, BIM-C, FIAIME, DAIPM, CBIST *, e Scott D. Bender, PhD, ABPP-CN KEYWORDS Traumatic brain injury Validity Response bias Malingering Physical examination Cognition Behavior Forensic KEY POINTS Differential diagnosis in cases of claimed post-traumatic brain injury (TBI) impairment re- quires an understanding of the principles of validity assessment and their application in the context of physical and cognitive-behavioral assessment. Clinicians must appreciate the nuances between effort and response bias assessment, and performance and symptom validity testing in the context of assessing anyone with a reported history of TBI, particularly when there are potential secondary gain incentives present that may impact examination validity. Practitioners must be aware that there are many reasons for symptom magnification and that the driving factors may not necessarily be consciously mediated or discoverable by the clinician/examiner. Continued INTRODUCTION In the context of impairment and disability evaluations following claimed or docu- mented traumatic brain injury (TBI), it is crucial to understand the importance of validity assessment methodologies, and their impact on impairment assessment accuracy Disclosure Statement: Dr N.D. Zasler reports no funding support for this work. He acknowl- edges ownership of Concussion Care Center of Virginia Ltd and Tree of Life Services, Inc, which are providers of health care
    [Show full text]
  • Malingering.2018.Neuroinstitute Format
    Malingering: The Impact of Effort on Outcome Gordon J. Horn, PhD Clinical Neuropsychologist National Deputy Director of Clinical Outcomes Introduction Sometimes it is quite difficult to distinguish effort from many other things that influence outcomes. Sometimes it is difficult to distinguish between various conditions or disorders by presentation alone. An example…. Which one is malingering? Answer: None Learning Objectives At the conclusion of this activity, the participant will be able to… 1. Understand the term “effort” and how this may be positive, negative, or involuntary. 2. Understand Somatic symptom disorder. 3. Understand Conversion disorder. 4. Understand Malingering (and Factitious Disorder) 5. Understand how to detect and assess for each of the conditions described in a rehabilitation context. Effort. … is difficult to assess and may have positive or negative effects. Therefore, it can be assessed in multiple ways so that accuracy increases. Does standing on a ball take effort? Effort - Defined Clinically: . “Exertion of physical and/or mental effort” “An earnest or strenuous attempt” Statistically: “Reliability and Validity measurement” Legally: “Truthfulness” Dictionary.com Effort Effort is difficult to assess and may have positive or negative effects. Therefore, it can be assessed in multiple ways so that accuracy increases. In rehabilitation, effort can be as simple as showing up for the correct appointment at the correct time. It may also include compliance with homework. It may be seen in the completion of therapist request. In outcomes, effort may be related to unexpected changes in score on outcome measures. For instance, those of you with NeuroRestorative know that if we see an outcome measure that is “out of the ordinary” then we directly call the programs or send the data back for rescoring.
    [Show full text]
  • Definition, Diagnosis, and Forensic Implications of Postconcussional
    Review Article Definition, Diagnosis, and Forensic Implications of Postconcussional Syndrome RYAN C.W. HALL, M.D. RICHARD C.W. HALL, M.D. MARCIA J. CHAPMAN Injuries from blows to the head often are manifested only as subjective complaints. Postconcus- sional syndrome thus can be feigned for financial or psychological gain. The authors review the pathology of brain trauma, symptoms of postconcussional syndrome, and criteria for diagnosis. In addition to somatic deficits, psychological and cognitive problems are common. The likelihood and severity of postconcussional syndrome are greater for women. Malingering may be suspected in cases involving litigation, and tests to detect it are available. Treatment for postconcussional syndrome depends on the specific symptoms. Pharmacotherapies may be helpful, but care should be used in prescribing drugs that could produce deleterious CNS effects. (Psychosomatics 2005; 46:195–202) he fact that being hit in the head is detrimental to one’s jured workers.1,2 Charcot later weighed in with his belief Thealth has been known since the dawn of time. Where that the long-term symptoms resulting from “mild head the controversy has raged in academic, clinical, and legal injury” were due to “hysteria and neurasthenia” (i.e., vague medicine over the years has been in the answers to the fatigue and confusion brought on by “psychological fac- following questions: What is the force necessary to cause tors”).1,3 By 1934, the diagnostic entities of “railroad head trauma? How is it manifested? and What can one spine,”
    [Show full text]
  • Psychogenic Nonepileptic Seizures TAOUFIK M
    Psychogenic Nonepileptic Seizures TAOUFIK M. ALSAADI, M.D., and ANNA VINTER MARQUEZ, M.D. University of California, Davis, Medical Center, Sacramento, California Psychogenic nonepileptic seizures are episodes of movement, sensation, or behaviors that are similar to epileptic seizures but do not have a neurologic origin; rather, they are somatic manifestations of psychologic distress. Patients with psychogenic nonepileptic seizures frequently are misdiagnosed and treated for epilepsy. Video-electroencepha- lography monitoring is preferred for diagnosis. From 5 to 10 percent of outpatient epilepsy patients and 20 to 40 per- cent of inpatient epilepsy patients have psychogenic nonepileptic seizures. These patients inevitably have comorbid psychiatric illnesses, most commonly depression, posttraumatic stress disorder, other dissociative and somatoform disorders, and personality pathology, especially borderline personality type. Many patients have a history of sexual or physical abuse. Between 75 and 85 percent of patients with psychogenic nonepileptic seizures are women. Psycho- genic nonepileptic seizures typically begin in young adulthood. Treatment involves discontinuation of antiepileptic drugs in patients without concurrent epilepsy and referral for appropriate psychiatric care. More studies are needed to determine the best treatment modalities. (Am Fam Physician 2005;72:849-56. Copyright© 2005 American Academy of Family Physicians.) onepileptic seizures are invol- Since ancient times, nonepileptic seizures untary episodes of movement,
    [Show full text]
  • PSYCHIATRIC CLINICS of NORTH AMERICA Malingering in the Medical Setting
    Psychiatr Clin N Am 30 (2007) 645–662 PSYCHIATRIC CLINICS OF NORTH AMERICA Malingering in the Medical Setting Barbara E. McDermott, PhDa,b,*, Marc D. Feldman, MDc aUniversity of California, Davis School of Medicine, Department of Psychiatry and Behavioral Sciences, Division of Psychiatry and the Law, 2230 Stockton Blvd, 2nd Floor, Sacramento, CA 95817, USA bClinical Demonstration/Research Unit, Napa State Hospital, 2100 Napa Vallejo Hwy, Napa, CA 94558, USA cThe University of Alabama, Tuscaloosa, 2609 Crowne Ridge Court, Birmingham, AL 35243–5351, USA ‘‘ alingering’’ is defined as the conscious feigning, exaggeration, or self-induction of illness (either physical or psychological) for an M identifiable secondary gain [1]. In the medical setting, that sec- ondary gain can be diverse, including the receipt of monies (legal settlements or verdicts, worker’s compensation, disability benefits); the procurement of abus- able prescription medications, such as opioids or benzodiazepines; the avoidance of unpleasant work or military duty; or simply access to a warm, dry hospital bed. In other cases, the incentives can be more subtle, such as avoidance of onerous household responsibilities. Malingering is distinguished from factitious disorder by its motivation: in clear-cut cases, the malingerer consciously falsifies or induces illness or symptoms for a specific purpose that is identifiable, once details of the malingerer’s life are known. In contrast, in factitious disorder, symptom produc- tion is conscious for a primary gain: the assumption of the ‘‘sick role’’ [2]. The rea- sons that the individual desires the sick role are presumably primarily unconscious [3]. In psychiatry, malingering of mental illness is often suspected in both criminal and civil cases, where the secondary gain can be substantial [4,5].
    [Show full text]
  • Somatising Disorders Untangling the Pathology
    THEME Mental health Somatising disorders Untangling the pathology BACKGROUND Somatising disorders are a common, complex and disabling cluster of disorders. Research suggests that general practitioners find this group of patients challenging. The disorders are complicated by the fact that doctors play a role in both their aetiology and maintenance. The interaction between the illness worry of the patient and the disease worry of the doctor can lead to escalating disability and the risk of iatrogenic disease. Louise Stone OBJECTIVE MBBS, BA, MPH, DipRACOG, In this article, common conceptual frameworks for somatising disorders are discussed and a framework for managing FRACGP, FACRRM, is Medical these complex disorders is presented. Educator, SIGPET, New South Wales. [email protected] DISCUSSION Patients with somatising disorders need to establish a positive therapeutic relationship with their doctor that David M Clarke encourages open and honest discussion of their illness. General practitioners need to strike a balance between empathy MBBS, PhD, is Professor, for the patient’s suffering and collusion in their disease worry. Excessive intervention and investigation should be School of Psychology, Psychiatry and Psychological avoided. This may require considerable professional support for the doctor. Medicine, Monash University, Victoria, Clinical Director, General Hospital and Primary Care Psychiatry, Monash Medical Centre, Victoria, and Janine, 54 years of age, has a history of depression occupational therapists provides temporary periods of Research Advisor, beyondblue: and joint pain. When you see her she is teary and talks improvement. As her doctor, you have vacillated between the national depression initiative. a lot about the impact of the pain on her life.
    [Show full text]
  • Factitious Disorders and Malingering: Challenges for Clinical Assessment and Management
    Series Factitious disorders 2 Factitious disorders and malingering: challenges for clinical assessment and management Christopher Bass, Peter Halligan Lancet 2014; 383: 1422–32 Compared with other psychiatric disorders, diagnosis of factitious disorders is rare, with identifi cation largely dependent Published Online on the systematic collection of relevant information, including a detailed chronology and scrutiny of the patient’s March 6, 2014 medical record. Management of such disorders ideally requires a team-based approach and close involvement of the http://dx.doi.org/10.1016/ primary care doctor. As deception is a key defi ning component of factitious disorders, diagnosis has important S0140-6736(13)62186-8 implications for young children, particularly when identifi ed in women and health-care workers. Malingering is See Online/Comment http://dx.doi.org/10.1016/ considered to be rare in clinical practice, whereas simulation of symptoms, motivated by fi nancial rewards, is regarded S0140-6736(13)62640-9 as more common in medicolegal settings. Although psychometric investigations (eg, symptom validity testing) can See Online/Series inform the detection of illness deception, such tests need support from converging evidence sources, including detailed http://dx.doi.org/10.1016/ interview assessments, medical notes, and relevant non-medical investigations. A key challenge in any discussion of S0140-6736(13)62183-2 abnormal health-care-seeking behaviour is the extent to which a person’s reported symptoms are considered to be a This is the second in a Series of product of choice, or psychopathology beyond volitional control, or perhaps both. Clinical skills alone are not typically two papers about factitious disorders suffi cient for diagnosis or to detect malingering.
    [Show full text]
  • The Distinction Between Malingering and Mental
    THE DISTINCTION BETWEEN MALINGERING AND MENTAL ILLNESS IN BLACK FORENSIC PATIENTS by BASIL GREGORY BUNTTING Submitted in partial fulfillment of the requirements for the degree of DOCTOR OF MEDICINE In the Department of Psychiatry Faculty of medicine University of Natal DURBAN 1997 i ABSTRACT One of the main problems facing the p sychiatrist in forensic psychiatry is the distinction between malingering and mental illness especially in Zulu speaking patients. This study identified twenty items from the literature and clinical practice that separate malingering from mental illness. The validity of these items was assessed through an experimental, cross-sectional study design which compared two groups. These were a sample of fifty malingering African patients, male and female and a control group of fifty mentally-ill African forensic patients who were classified as State Patients. Since the data was categorical, that is, the outcome was either positive (that is malingering) or negative (that is mentally ill) the groups were compared by employing s u c h methods as the chi-square test and Fisher's exact test. Seventeen items we re found to be statistically significant and were regarded as valid items that separate malingering from mental illness . Then the e ffectivBness of these seventeen items in separating malingering from mental illness was determined by calculating their sensitivity, specificity, their false positive rate and their false negative rate. The items fell into four categories or groups. Group I are those three items with a high sensitivity, a i1 high specificity, a few false positives, a few false negatives, high positive predictive values and high negative predictive values.
    [Show full text]
  • A Teen with Seizures, Amnesia, and Troubled Family Dynamics Shephali Sharma, MD, and Julie Alonso-Katzowitz, MD
    Cases That Test Your Skills A teen with seizures, amnesia, and troubled family dynamics Shephali Sharma, MD, and Julie Alonso-Katzowitz, MD Ms. A, age 13, is admitted for acute-onset amnesia. She has been How would you treated for intractable seizures for 5 months. What could be handle this case? Answer the challenge causing her amnesia? questions throughout this article CASE Seizures, amnesia Ms. A is admitted to the inpatient medi- Ms. A, age 13, who has a history of seizures, cal unit for further work up. Along with the presents to the emergency department memory loss and seizures, she reports visual (ED) with sudden onset of memory loss. Her hallucinations. family reports that she had been spend- ing a normal evening at home with family What could be causing Ms. A’s amnesia? and friends. After going to the bathroom, a) a seizure disorder Ms. A became acutely confused and b) malingering extremely upset, had slurred speech, and c) posttraumatic stress disorder did not recognize anyone in the room except d) traumatic brain injury her mother. Initial neurologic examination in the ED reports that Ms. A does not remember recent HISTORY Repeat ED visits or remote past events. Her family denies any Ms. A’s mother reports that 3 years ago her recent stressors. daughter was treated for tics with quetiapine Vital signs are within normal range. She and aripiprazole, prescribed by a primary care has mild muscle soreness and gait instability, physician. She received a short course of coun- which is attributed to a presumed postictal seling 6 years ago after her sister was sexually phase.
    [Show full text]
  • The Differential Diagnosis of Epilepsy: a Critical Review
    Epilepsy & Behavior 15 (2009) 15–21 Contents lists available at ScienceDirect Epilepsy & Behavior journal homepage: www.elsevier.com/locate/yebeh Review The differential diagnosis of epilepsy: A critical review S. Benbadis Comprehensive Epilepsy Program, University of South Florida and Tampa General Hospital, 2 Tampa General Circle, Tampa, FL 33606 article info abstract Article history: The wrong diagnosis of epilepsy is common. At referral epilepsy centers, psychogenic non-epileptic Received 18 February 2009 attacks are by far the most common condition found to have been misdiagnosed as epilepsy, with an Accepted 19 February 2009 average delay of 7–10 years. There are many ‘‘red flags” that can raise the suspicion of psychogenic Available online 21 February 2009 non-epileptic attacks. Syncope is the second most common condition misdiagnosed as epilepsy, and it is probably more common in outpatient populations. Other conditions more rarely misdiagnosed as epi- Keywords: lepsy include hypoglycemia, panic attacks, paroxysmal movement disorders, paroxysmal sleep disorders, Seizures TIAs, migraines, and TGA. Conditions specific to children include nonepileptic staring spells, breath-hold- Nonepileptic seizures ing spells, and shudder attacks. At all ages, the over-interpretation of EEGs plays an important part in the Differential diagnosis Paroxysmal neurologic symptoms misdiagnosis of epilepsy. Ó 2009 Elsevier Inc. All rights reserved. 1. Introduction [12,13]. In addition to being common, PNEAs represent a challenge in both diagnosis and in management. The terminology on the to- The wrong diagnosis of epilepsy is unfortunately common. Of pic has been variable and continues to be confusing. Various terms patients diagnosed with epilepsy who are seen at epilepsy centers, have been used, including pseudoseizures, nonepileptic seizures, 20% to 30% are found to have been misdiagnosed [1–3].
    [Show full text]