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Endorectal, Endoanal and Perineal Ultrasound University of Southern Denmark EFSUMB Recommendations for Gastrointestinal Ultrasound Part 3 Endorectal, Endoanal and Perineal Ultrasound Nuernberg, Dieter; Saftoiu, Adrian; Barreiros, Ana Paula; Burmester, Eike; Ivan, Elena Tatiana; Clevert, Dirk-André; Dietrich, Christoph F; Gilja, Odd Helge; Lorentzen, Torben; Maconi, Giovanni; Mihmanli, Ismail; Nolsoe, Christian Pallson; Pfeffer, Frank; Rafaelsen, Søren Rafael; Sparchez, Zeno; Vilmann, Peter; Waage, Jo Erling Riise Published in: Ultrasound International Open DOI: 10.1055/a-0825-6708 Publication date: 2019 Document version: Final published version Document license: CC BY-NC-ND Citation for pulished version (APA): Nuernberg, D., Saftoiu, A., Barreiros, A. P., Burmester, E., Ivan, E. T., Clevert, D-A., Dietrich, C. F., Gilja, O. H., Lorentzen, T., Maconi, G., Mihmanli, I., Nolsoe, C. P., Pfeffer, F., Rafaelsen, S. R., Sparchez, Z., Vilmann, P., & Waage, J. E. R. (2019). EFSUMB Recommendations for Gastrointestinal Ultrasound Part 3: Endorectal, Endoanal and Perineal Ultrasound. Ultrasound International Open, 5(1), E34-E51. https://doi.org/10.1055/a- 0825-6708 Go to publication entry in University of Southern Denmark's Research Portal Terms of use This work is brought to you by the University of Southern Denmark. Unless otherwise specified it has been shared according to the terms for self-archiving. If no other license is stated, these terms apply: • You may download this work for personal use only. • You may not further distribute the material or use it for any profit-making activity or commercial gain • You may freely distribute the URL identifying this open access version If you believe that this document breaches copyright please contact us providing details and we will investigate your claim. Please direct all enquiries to [email protected] Download date: 02. Oct. 2021 Review Nuernberg Dieter et al. EFSUMB Recommendations for Gastrointestinal … Ultrasound Int Open 2018; 00: 00–00 EFSUMB Recommendations for Gastrointestinal Ultrasound Part 3: Endorectal, Endoanal and Perineal Ultrasound Authors Dieter Nuernberg1,*, Adrian Saftoiu2,*, Ana Paula Barreiros3, Eike Burmester4, Elena Tatiana Ivan2, Dirk-André Clevert5, Christoph F. Dietrich6, Odd Helge Gilja7, Torben Lorentzen8, Giovanni Maconi9, Ismail Mihmanli10, Christian Pallson Nolsoe11, Frank Pfeffer12, Søren Rafael Rafaelsen13, Zeno Sparchez14, Peter Vilmann15, Jo Erling Riise Waage12 Affiliations Key words 1 Medical School Brandenburg Theodor Fontane, endorectal ultrasound, endoanal ultrasound, perineal ultrasound Gastroenterology, Neuruppin, Germany received 07.04.2018 2 Research Center in Gastroenterology and Hepatology, revised 23.11.2018 University of Medicine and Pharmacy Craiova, Craiova, accepted 01.12.2018 Romania 3 Deutsche Stiftung Organtransplantation, Head of Bibliography Organisation Center Middle, Frankfurt, Germany DOI https://doi.org/10.1055/a-0825-6708 4 Department of Internal Medicine/Gastroenterology, Published online: 2019 Sana-Kliniken Lübeck, Lübeck, Germany Ultrasound Int Open 2019; 5: E34–E51 5 Department of Clinical Radiology, Interdisciplinary © Georg Thieme Verlag KG Stuttgart · New York Ultrasound-Center, University of Munich-Grosshadern ISSN 2199-7152 Campus, Munich, Germany 6 Caritas-Krankenhaus, Medizinische Klinik 2, Bad Correspondence Mergentheim, Germany Prof. Adrian Saftoiu 7 National Centre for Ultrasound in Gastroenterology, Research Center in Gastroenterology and Hepatology Haukeland University Hospital and Department of University of Medicine and Pharmacy Craiova Clinical Medicine, University of Bergen, Bergen, Norway Macinului 1 8 Ultrasound Section, Division of Surgery, Department of 200640 Craiova, Romania Gastroenterology, Herlev Hospital, University of Tel.: + 40/744/823 355, Fax: + 40/251/310 287 Copenhagen, Herlev, Denmark [email protected] 9 Gastroenterology Unit, Department of Biomedical and Clinical Sciences, “L.Sacco” University Hospital, Milan, ABSTRACT Italy 10 Istanbul University – Cerrahpasa, Cerrahpasa Medical This article represents part 3 of the EFSUMB Recommendations Faculty, Department of Radiology and ALKA Radyoloji and Guidelines for Gastrointestinal Ultrasound (GIUS). It provides Tani Merkezi, Istanbul, Turkey an overview of the examination techniques recommended by 11 Ultrasound Section, Division of Surgery, Department of experts in the field of endorectal/endoanal ultrasound (ERUS/ Gastroenterology, Herlev Hospital and Copenhagen EAUS), as well as perineal ultrasound (PNUS). The most important Academy for Medical Education and Simulation (CAMES), indications are rectal tumors and inflammatory diseases like fis- University of Copenhagen, Denmark tula and abscesses in patients with or without inflammatory bow- 12 Department of Surgery, Haukeland University Hospital el disease (IBD). PNUS sometimes is more flexible and convenient and Department of Clinical Medicine, University of compared to ERUS. However, the technique of ERUS is quite well Bergen, Bergen, Norway established, especially for the staging of rectal cancer. EAUS also 13 Colorectal Centre of Excellence, Clinical Cancer Centre, gained ground in the evaluation of perianal diseases like fistulas, University Hospital of Southern Denmark, Vejle, Denmark abscesses and incontinence. For the staging of perirectal tumors, 14 3rd Medical Department, "Iuliu Hatieganu" University of the use of PNUS in addition to conventional ERUS could be recom- Medicine and Pharmacy, Cluj-Napoca, Romania mended. For the staging of anal carcinomas, PNUS can be a good 15 Endoscopy Department, Copenhagen University Hospital option because of the higher resolution. Both ERUS and PNUS are Herlev, Herlev, Denmark considered excellent guidance methods for invasive interventions, such as the drainage of fluids or targeted biopsy of tissue lesions. For abscess detection and evaluation, contrast-enhanced ultra- * First 2 authors contributed equally to the manuscript. sound (CEUS) also helps in therapy planning. E34 Nuernberg D et al. EFSUMB Recommendations for Gastrointestinal … Ultrasound Int Open 2019; 5: E34–E51 Introduction nodes are recognized as round or oval hypoechoic structures as This article represents part 3 of the European Federation of Socie- compared to the perirectal tissue [1, 2]. ties for Ultrasound in Medicine and Biology (EFSUMB) Recommen- dations and Guidelines for Gastrointestinal Ultrasound (GIUS). It Examination technique provides an overview of the examination techniques recommend- For an accurate ERUS examination, the rectum needs to be prop- ed by experts in the field for EndoRectal (ERUS), EndoAnal Ultra- erly cleaned to avoid artifacts from residual stool. For this purpose, Sound (EAUS) and PeriNeal UltraSound (PNUS). Concerning ERUS, a cleansing enema is routinely given before the procedure, al- various other terms are used in the literature for the same tech- though a full-bowel preparation may be used to optimize imaging. nique, including transrectal ultrasound (TRUS), anorectal ultra- The examination is performed with the patient in the left lateral sound (ARUS), and endoanorectal ultrasound (EARUS). Due to decubitus or lithotomy (gynecological) position. Sedation is usu- standardization of the guideline, we preferred the arbitrary distinc- ally not necessary as it is a well-tolerated procedure [3]. A digital tion between ERUS and EAUS, with these being the abbreviations rectal examination and at least a rectosigmoidoscopy should used in the manuscript. precede ERUS examination, especially for tumor staging, in order Part 3 of the Guidelines for GastroIntestinal Ultrasound (GIUS) to describe the size and location of the lesion. A thorough exami- provides an overview of the examination of the anorectum and the nation of the tumor by flexible sigmoidoscopy prior to ERUS will fa- perineal region with the techniques of ERUS, EAUS, as well as PNUS. cilitate a targeted approach to areas of suspected invasion. PNUS is a method characterized as effective, inexpensive, safe, Either rigid blind rectal probes or flexible echoendoscopes en- available everywhere and associated with minimal pain, mostly be- abling radial or linear scanning may be used, with ultrasound fre- cause it is noninvasive and does not need a special application set quencies ranging between 5 MHz and 15 MHz. End-fire probes like or probe. However, it is also a rarely used diagnostic tool in daily those used for prostate examinations may also be used, especially practice. In contrast, the ERUS technique is quite well established, for proximal tumors and lymph node evaluation. These are incre- especially for the staging of rectal cancer. EAUS has also gained mentally adjusted according to the desired resolution and depth ground in the evaluation of anorectal diseases like fistulas, abscess- of penetration [1]. Rigid blind rectal probes are commonly used in es and incontinence. clinical practice due to their lower costs and availability. Flexible For each recommendation, levels of evidence (LoE) and grades echoendoscopes may be advanced under visual control up to the of recommendation (GoR) were included to evaluate the clinical level of the tumor and are able to pass through narrower lumens role in various applications. These were assigned according to the of stenosing tumors. Comparative studies between the 2 types of criteria of the Oxford Centre for Evidence-Based Medicine (http:// devices are currently limited and have shown contradictory results www.cebm.net/oxford-centre-evidencebased-medicine-levels-ev- for rectal cancer
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