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Introduction to Learning objectives • To Understand the basic structure of the skin Dermatology • To acquire the basic knowledge of the skin functions • Be able to describe skin lesions and presentations properly • Be familiar with the standard diagnostic tools in dermatology Dr. Sami N. Alsuwaidan

ASSCOCIATE PROFESSOR AND CONSULTANT IN DERMATOLOGY AND LASER SURGERY DEPARTMENT OF DERMATOLOGY KING SAUD UNIVERSITY RIYADH, SAUDIA ARABIA

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Important functions of the Dermatology skin

Skin, , nails, and mucous - Protection against external injury membranes (mouth and genitila). - Fluid balance - Temperature buffering - Synthesis of Vit. D - Immune system - Cosmetic function

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Cornified layer

Epidermis Granular layer

Why Dermatology ? Spinous layer

Dermis Basal layer

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1 1 Skin Anatomy 1 2 (dermoepidermal junction) Epidermis 3 4 Subcutaneous fat

 Epidermis: Four layers (from outside – inside) 1. Cornified layer 2. Granular layer Dermis 3. Spinous layer 4. Basal layer

 Dermis contains: 1. fibers 2. Elastic fibers 3. Ground substances 4. Blood vessels 5. Nerves.

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Skin Appendages

  Arrector Pilli muscle   Eccrine Hair follicle  Apocrine sweat glands

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Nail Anatomy

Sebaceous gland

Eccrine gland

Apocrine gland

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1 2 Examination Primary Lesions 1. Morphology 2. Configuration Secondary lesions 3. Distribution

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Primary Lesions

Macule Papule

Plaque Nodule

Wheal

Vesicle Bulla

Pustule

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1 4 Secondary lesions

Crust Scale Ulceration Excoriation Scar Fissure Lichenification

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30 a

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Color and Shape Distribution Configuration

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Dermatographism : When you stroke the Some specific signs in normal skin  edema and erythema (you can write on skin!) .Seen in physical urticaria Dermatology Kobener Phenomenon : Induction of new skin lesions on previously normal appearing skin by truma e.g. in psoriasis, , lichen planus

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1 8 Dermatographism Kobener Phenomenon

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Additional skin examination: ~Wood’s Lamp : Produces long wave ultraviolet light(UVA). e.g. Vitiligo  milky white Tinea Versicolor  golden INVESTIGATIVE TOOLS Tinea Capitis (caused by microsporum)  yellow green Erytherasma  coral red

~Dermatoscopy : Helpful to differentiate benign from malignant pigmented lesions.

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Investigations:

*KOH and fungal culture •Scrap skin scales  put over glass slide •Add KOH 10% -- warm gently •See under microscope •You may see hyphae and/ or spores

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1 9 Skin Prick Test

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Patch Test Investigations:

Skin biopsy local anasthesia, different types: •Punch •Shave •Excisional •Incisional

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Treatment: Topical Treatments Topical Various formulations: •Ointment Systemic •Cream •Gel •Solution •Lotion

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Phototherapy

Topical steroids Ultraviolet light A or B with or without psoralen PUVA (Psoralen + UVA) 7 Categories: New modalities: according to strength Narrow band UVB UVA – 1 Excimer laser(308nm)

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1 11 Dermatology subspecialties

 Pediatric dermatology  Photomedicine  Laser  Hair Disorders and Transplantation  Dermatologic surgery  Allergy/Contact dermatitis  Dermatopathology  Immunodermatology  Others

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