University of South Florida Scholar Commons Graduate Theses and Dissertations Graduate School 2011 Crystal Engineering of Pharmaceutical Cocrystals Sreya Mukherjee University of South Florida,
[email protected] Follow this and additional works at: https://scholarcommons.usf.edu/etd Part of the American Studies Commons, and the Inorganic Chemistry Commons Scholar Commons Citation Mukherjee, Sreya, "Crystal Engineering of Pharmaceutical Cocrystals" (2011). Graduate Theses and Dissertations. https://scholarcommons.usf.edu/etd/3258 This Thesis is brought to you for free and open access by the Graduate School at Scholar Commons. It has been accepted for inclusion in Graduate Theses and Dissertations by an authorized administrator of Scholar Commons. For more information, please contact
[email protected]. Crystal Engineering of Pharmaceutical Cocrystals By Sreya Mukherjee A thesis submitted in partial fulfillment of the requirements for the degree of Master of Science Department of Chemistry College of Arts and Sciences University of South Florida Major Professor: Michael J. Zaworotko, Ph.D. Abdul Malik, Ph.D. Mark McLaughlin, Ph.D. Roland Shytle, Ph.D. Date of Approval: July 8, 2011 Keywords: BCS, Solubility, Hydrogen bond, Pentoxifylline, Caffeine Copyright © 2011, Sreya Mukherjee DEDICATION To my parents, husband and brother. ACKNOWLEDGEMENTS I would like to express my sincere gratitude to my professor, Dr. Michael Zaworotko for giving me the opportunity to conduct research under his guidance and supervision. I am sure that this will help me achieve much more in the future. I would also like to thank my committee members, Dr. Abdul Malik, Dr. Mark McLaughlin and Dr. Roland Shytle for their valuable time, feedback, suggestions and help.