AMIA 2017 Annual Symposium

Washington, DC, USA 4 - 8 November 2017

Volume 1 of 3

ISBN: 978-1-5108-5307-2 Printed from e-media with permission by:

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Curran Associates, Inc. 57 Morehouse Lane Red Hook, NY 12571 USA Phone: 845-758-0400 Fax: 845-758-2633 Email: [email protected] Web: www.proceedings.com TABLE OF CONTENTS

VOLUME 1

Enabling Interoperability between Healthcare Devices and EHR Systems...... 1 Swapna Abhyankar ; Paul Schluter ; Kathryn Bennett ; Daniel J. Vreeman ; Clement J. McDonald

Applying a Process-based Framework to examine Interunit Patient Transfers ...... 3 Joanna Abraham ; Shirley Burton ; Imade Ihianle

Medical Benefit Drug Claims: Assessing the NDC Documentation Gap ...... 5 Terrence J. Adam ; Bithia Anderson ; Angeline Carlson ; Mahsa Salsabili ; Glenn Trygstad ; Stephen Schondelmeyer

Advanced Use of EHRs in US Hospitals and the Emergence of a Digital "Use" Divide ...... 7 Julia Adler-Milstein ; A J. Holmgren

Phenotyping Physiologic Measurement of Lung Function in a Large Electronic Health Record Using Automated Tools...... 9 Kathleen M. Akgün ; Keith Sigel ; Kei Cheung ; Farah Kidwai-Khan ; Alex K. Bryant ; Cynthia Brand ; Amy C. Justice ; Kristina Crothers

Why Predicting Postprandial Glucose Using Self-monitoring Data is Difficult...... 11 David Albers ; Matthew Levine ; Andrew Stuart ; Bruce Gluckman ; George Hripcsak ; Lena Mamykina

Pain Assessment Automatic Documentation Initiated by Patients and Parents: A Case Study from the University of Minnesota Masonic Children’s Hospital ...... 13 Ranyah Aldekhyyel ; Michael Pitt ; Yan Wang ; Genevieve B. Melton

Quick Sequential [Sepsis-related] Organ Failure Assessment (qSOFA) and St. John Sepsis Surveillance Agent to Detect Patients At-Risk of Sepsis: An Observational Cohort Study...... 15 Robert C. Amland ; Bharat B. Sutariya

Identifying and Predicting Falls among Elderly Residents of Baltimore City Using Hospital Discharge Summaries and Health Information Exchange Data...... 17 Laura Anzaldi ; Elyse Lasser ; Joshua Sharfstein ; Hadi Kharrazi

Differing Patterns of Satisfaction and Perception Among Clinical and Non-clinical Users Following Replacement of a Legacy EHR System...... 19 Nate C. Apathy ; Joshua R. Vest ; Nir Menachemi ; John W. Putz ; Justin Morea ; Christopher A. Harle

Novel Targeting of Clinical Decision Support: Utilizing Machine Learning To Improve Provider Acceptance – Repeat Imaging as an Example...... 21 Wasim Al Assad ; Ivan Ip ; Li Zhou ; Ramin Khorasani

Clinical Trial Eligibility Criteria Fail to Meet Burden of Generalizability ...... 23 Amelia J. Averitt ; Chunhua Weng ; Adler Perotte

Using Computer Agents to Explain Clinical Test Results...... 25 Renato F. Azevedo ; Kuangxiao Gu ; Yang Zhang ; Victor Sadauskas ; Tarek Sakakini ; Daniel Morrow ; Mark Hasegawa-Johnson ; Thomas S. Huang ; Suma Bhat ; Ann Willemsen-Dunlap ; Donald J. Halpin ; James F. Graumlich ; William Schuh

EHR-based Quality Measurement to Reduce Antibiotic Use in Children...... 27 L. Charles Bailey ; Hanieh Razzaghi ; Elizabeth R. Earley ; Jeanhee Moon ; Levon Utidjian ; Jessica Hawkins ; Chris Forrest

Usability and Acceptability of a System to Identify Pediatric Patients at Risk of 30-day Hospital Readmission Prior to Discharge...... 29 Amie Barda ; Lingyun Shi ; Andrew H. Urbach ; Srinivasan Suresh ; Fuchiang Tsui

Large-Scale Text Mining of Social Determinants from Electronic Health Records: Case Studies of Homelessness and Adverse Childhood Experiences...... 31 Cosmin A. Bejan ; John Angiolillo ; Douglas Conway ; Robertson Nash ; Jana Shirey-Rice ; Loren Lipworth-Elliot ; Robert M. Cronin ; Jill Pulley ; Sunil Kripalani ; Shari Barkin ; Kevin B. Johnson ; Joshua C. Denny

A Digital Health Advisor for High-Need, High-Cost Patients: Exploring Needs, Functions and System Constraints...... 33 Onil Bhattacharyya ; Arnav Shah ; Lovisa Gustafsson ; Kathryn Mossman ; Eric Schneider

The OpenNotes Patient and Family Reporting Tool: Engaging Patients and Families as Partners in Safety and Quality ...... 35 Fabienne C. Bourgeois ; Macda Gerard ; Alan Fossa ; Lindy Lurie ; Dianne Arnold ; Monique Mello ; Jenny Sadler ; Patricia A. Folcarelli ; Sigall Bell

Evaluating the Quality of Patient Address Data in an EHR system...... 37 Michael N. Cantor

Data-driven Risk Characterization and Prediction of Renal Failure among Diabetic Type 2 Patients using Electronic Medical Records...... 39 Prithwish Chakraborty ; Vishrawas Gopalakrishnan ; Sharon Hensley Alford ; Faisal Farooq

Using Electronic Health Records Data for Comparative Effectiveness Research ...... 41 David Cheng ; Ashwin Ananthakrishnan ; Tianxi Cai

Patient and Physician Predictors of Patient Receipt of Empiric Therapies Recommended by a Computerized Decision Support System: A Cohort Study...... 43 Angela Chow ; David C. Lye ; Onyebuchi A. Arah

Opportunities and Challenges for an Interdisciplinary Team to Guide Adoption of Technology to Dissipate Threats to Patient Safety in Real-Time...... 45 Anuj K. Dalal ; Theresa E. Fuller ; Pamela M. Neri ; Dominic Breuer ; David Bates ; James Benneyan

Use of Clinical Phenotypes and Non-negative Tensor Factorization for Heart Failure Prediction...... 47 Yu Deng ; Al'Ona Furmanchuk ; Robert Chen ; Faraz S. Ahmad ; Jimeng Sun ; Abel N. Kho

Meeting User Needs for a Data Discovery Index of Biomedical Big Data...... 49 Ram Dixit ; Deevakar Rogith ; Vidya Narayana ; Mandana Salimi ; Anupama E. Gururaj ; Lucila Ohno-Machado ; Hua Xu ; Todd R. Johnson

Leveraging Electronic Health Record Data for Community Health Assessment and Surveillance ...... 51 Brian E. Dixon ; P. Joseph Gibson ; Karen F. Comer ; Jian Zou ; Marc Rosenman ; Jennifer Williams

Predictors of OpenNotes Use Among Veterans receiving Mental Health Care ...... 53 Steven K. Dobscha ; Lauren M. Denneson ; Maura Pisciotta ; Donald S. Bourne ; David Phillips-Moses ; Susan Woods

The Role of Chronic Inflammation as a Response Biomarker to Immune Checkpoint Inhibition in Cancer...... 55 Sherif M. El-Refai ; Val R. Adams ; Esther P. Black ; Jeffery C. Talbert

Applying Unsupervised Learning to Characterize Rare Observations in Clinical Data: the DQe-p Tool ...... 57 Hossein Estiri ; Jeffrey G. Klann ; Kavishwar B. Wagholikar ; Shawn N. Murphy

Decision Support to Effeciently Identify Patients for Advanced Heart Failure Therapies...... 59 Scott Evans ; Abdallah Kfoury ; Benjamin D. Horne ; Jim Lloyd ; Jose Benuzillo ; Kismet Rasmusson ; Colleen Roberts ; Donald Lappe

Using Visual Analytics and Patient-Generated Data to Support Clinical Decision-Making in the Context of Nutritional Therapy for Individuals with Diabetes ...... 61 Daniel J. Feller ; Marissa Burgermaster ; Lena Mamykina

New Relevance Search Algorithm for PubMed ...... 63 Nicolas Fiorini ; Zhiyong Lu

Forecasting the Maturation of EHR Functions Among US Hospitals...... 65 Eric Ford ; Hadi Kharrazi

Creating a Computable Phenotype for Pregnancy for Clinical Research ...... 67 Bret J. Gardner ; Jay Pedersen ; James R. Campbell ; James C. McClay

Design and Development of an Automated Healthcare Consumer Information Resource on Infectious Disease Activity in the State of Utah ...... 69 Per H. Gesteland ; Ken Korgenski

Measuring the Value of EHR’s Free-text in Identifying Geriatric Risk Factors ...... 71 Fardad Gharghabi ; Laura Anzaldi ; Thomas Richards ; Jonathan Weiner ; Hadi Kharrazi

A Conceptual Representation of Exposome in Translational Research...... 73 Ramkiran Gouripeddi ; Nicole Burnett ; Mollie R. Cummins ; Julio Facelli ; Katherine A. Sward

Efficient Remediation of Terms Inactivated by Dictionary Updates...... 75 Benjamin J. Gross ; David H. Dubois ; Mark Twelves ; Roberto A. Rocha

A Six-Year Follow-Up of Clinical Decision Support System User Acceptability: Practice Makes Progress ...... 77 Randall W. Grout ; Erika R. Cheng ; Aaron E. Carroll ; Stephen M. Downs ; Nerissa S. Bauer

Impact of VA Health Information Exchange Upon the Overuse of Laboratory and Imaging Tests...... 79 David A. Haggstrom ; Susan Perkins ; Susan Ofner ; Laura Myers ; Dustin French ; Marc Rosenman ; Jason Larson ; Michael Weiner ; Brian Dixon

Interactive Machine Learning for Medical Research: A Framework to Enhance the Engagement of Clinical Researchers ...... 81 Bibo Hao ; Yiqin Yu ; Wen Sun ; Yingxue Li ; Guotong Xie

Gene Annotation Bias Impedes Biomedical Research...... 83 Winston A. Haynes ; Aurelie Tomczak ; Purvesh Khatri

Implementing Automated Data Reporting to Improve Early Hearing Care ...... 85 Shan He ; Christine Perfili ; Darren K. Mann ; Matt S. Hoffman ; Viral Shah ; Gary Anderson ; Rishabh Bhatia ; Sidney N. Thornton

Integrating Patient Registries into Enterprise wide Patient-Discovery Strategies ...... 87 Christopher Herrick ; Alyssa Goodson ; Wayne Chan ; Lori C. Phillips ; Michael Mendis ; Shawn N. Murphy

Interpretable Clustering for Prototypical Patient Understanding: A Case Study of Hypertension and Depression Subgroup Behavioral Profiling in National Health and Nutrition Examination Survey Data...... 89 Pei-Yun S. Hsueh ; Subhro Das

How Do Physcians Read Electronic Progress Notes?...... 91 Gretchen M. Hultman ; Jenna Marquard ; Swaminathan Kandaswamy ; Elizabeth A. Lindemann ; Genevieve B. Melton

Using Social Networking Analysis to Understand the Importance of Patients and Caregivers in Online Teams of Care...... 93 Trevor Jamieson ; Michael F. Chiang ; Teja Voruganti ; Allison Kurahashi ; Alyssa Bertram ; Sara Subramaniam ; Amna Husain

Participatory Design of Probability-Based Decision Support Tools for In-Hospital Nurses ...... 95 Alvin D. Jeffery ; Laurie L. Novak ; Betsy B. Kennedy ; Mary S. Dietrich ; Lorraine C. Mion

Building an FHIR Ontology Based Data Access Framework with the OHDSI Data Repositories...... 97 Guoqian Jiang ; Guohui Xiao ; Richard C. Kiefer ; Eric Prud’Hommeaux ; Harold R. Solbrig

Performance of Algorithms Using Healthcare Claims and Electronic Health Record Clinical Notes to Identify Relapsing-Remitting Multiple Sclerosis in U.S. Integrated Delivery Network Healthcare Database ...... 99 Aaron Kamauu ; John Holmén ; Christopher Fillmore ; Hoa Le ; Andrew Wilson ; Chi Truong ; Canter Martin ; Schiffon Wong

A Comparison of Using Full and Partial Information from Administrative Claims Data to Predict Future Health Care Costs ...... 101 Hong J. Kan ; Hadi Kharrazi ; Hsien-Yen Chang ; Jonathan Weiner

Agile Clinical Decision Support Development...... 103 Vaishnavi Kannan ; Mujeeb Basit ; Duwayne L. Willett

Analyzing Prevalence of Obesity among VHA Patients Using Clinical, Temporal, and Geographical Data Extracted from a Nationwide EHR ...... 105 Hadi Kharrazi ; Stephan Fihn ; Tamara Box ; Jonathan Weiner

Consumer Views of Electronic Health and Genetic Data Sharing: Findings of a National Survey...... 107 Katherine K. Kim ; Lucila Ohno-Machado

Examining the Coverage of Nursing Content in the UMLS-CORE Problem List ...... 109 Tae Youn Kim ; Nicholas Hardiker

Reuse of PCORnet Data to Support the Precision Medicine Initiative: Data Model Harmonization ...... 111 Jeffrey G. Klann ; Matthew A. Joss ; Kevin Embree ; Shawn N. Murphy

Evaluation of Text Mining Methods to Support Reporting Public Health Notifiable Diseases Using Real-World Clinical Data...... 113 Matthias Kochmann ; Jiachen Wang ; Brian Dixon ; Suranga Kasthurirathne ; Shaun Grannis

Cardioprotective Drugs and Incident Dementias in Medicare’s Big Data...... 115 Fabricio S. P. Kury ; Seo H. Baik ; Clement J. McDonald

Generating a Test of Electronic Health Record Narrative Comprehension with Item Response Theory ...... 117 John P. Lalor ; Hao Wu ; Li Chen ; Kathleen Mazor ; Hong Yu

Comorbidity Miner: An Open Source Interactive Tool for Mining Disparate Electronic Health Data Sources...... 119 Ashley S. Lee ; Indra N. Sarkar ; Genevieve B. Melton ; Yuanqing Liu ; Vivekanand Sharma ; Elizabeth S. Chen

Usability and Feasibility of a Mobile App for Nursing Student Handoff Education...... 121 Mikyoung Lee ; Catherine Bailey ; Peggy Mancuso ; Patti Hamilton

Clustering Vital Sign Observations Using Unsupervised Random Forest...... 123 Dae Hyun Lee ; Meliha Yetisgen

Patient-Reported Outcomes in Clinical Use: Clinician Perspectives...... 125 Cynthia Lerouge ; Andrea L. Hartzler ; Liz Kellogg ; Mary Beth Hasselquist ; Danielle C. Lavallee

When to Re-order Laboratory Tests? Learning Lab Shelf-life...... 127 Gal Levy-Fix ; Sharon Lipsky Gorman ; Noemie Elhadad

User-Centered Design of a Collaborative Genetic Variant Interpretation Tool ...... 129 Wayne H. Liang ; Bas De Veer ; Diane M. Korngiebel ; Annie T. Chen ; Gail P. Jarvik ; Peter Tarczy-Hornoch ; David R. Crosslin

Promoting Adoption and Effective Use of Continuous Patient Monitoring Technology in the Acute Care Setting...... 131 Graham Lowenthal ; Stuart R. Lipsitz ; Catherine S. Yoon ; Perry G. An ; Suzanne Salvucci ; Christine Shaughnessy ; Sharon Keogh ; David Bates ; Patricia C. Dykes

Recurrent Neural Networks for Classifying Relations in Clinical Notes ...... 133 Yuan Luo

A Pilot Randomized Trial to Train Vulnerable Primary Care Patients to Use an Online Patient Portal Website...... 135 Courtney Lyles ; Lina Tieu ; Stephen Kiyoi ; Shobha Sadasivaiah ; Mekhala Hoskote ; Neda Ratanawongsa ; Urmimala Sarkar ; Dean Schillinger

Leveraging SNOMED CT Relationships for Mapping Disease Codes with Different Levels of Abstraction Between EHR Systems...... 137 Sina Madani ; Shari Just ; Scott D. Nelson ; S T. Rosenbloom ; Asli O. Weitkamp

Development of a Wrist-Worn Sensor to Improve Medication Adherence: Designing for Diverse User Behaviors and Technology Preferences...... 139 Jenna Marquard ; Barry Saver ; Swaminathan Kandaswamy ; Vanessa Martinez ; Jane Simoni ; Joanne Stekler ; Deepak Ganesan ; Sean Noran ; James Scanlan

Turning Off Medication Alerts to Reduce Clinical Decision Support Overrides ...... 141 Allison B. McCoy ; Eric J. Thomas ; Marie Krousel-Wood ; Ryan P. Walsh ; Adam Wright ; Dean F. Sittig

Beyond ResearchKit: User Engagement with Phendo, a Novel App for Self-tracking and Research...... 143 Mollie McKillop ; Sylvia English ; Sharib Khan ; Chintan Patel ; Noemie Elhadad

Usability Testing to Guide Development of a Clinical Decision Support System for Substance Use Screening and Interventions in Primary Care...... 145 Jennifer McNeely ; Andre W. Kushniruk ; Sarah Farkas ; Aida Vega ; Eva Waite ; Lauren Peccoralo ; Melanie Harris ; Christine Chollak ; Richard N. Rosenthal ; John Rotrosen ; Joseph Kannry

Identification of Clinically Meaningful Clusters of Multi-morbidity in a National Cohort of Adults Using Unsupervised Learning...... 147 Che Ngufor ; Rozalina G. McCoy ; Lixia Yao ; Lindsey R. Sangaralingham ; Shannon M. Dunlay ; Nilay D. Shah

Designing and Evaluating an Automated System for Real-time Medication Administration Error Detection in a Neonatal Intensive Care Unit ...... 149 Yizhao Ni ; Todd Lingren ; Eric S. Hall ; Mattew Leonard ; Kristin Melton ; Eric Kirkendall

Reducing Variation in Core Measures Data through Automation...... 151 Matthew A. Oberhardt ; Hojjat Salmasian ; Dena Goffman ; David K. Vawdrey

The Impact of Simulation on Electronic Health Record Use Patterns among Pediatric Residents...... 153 Evan Orenstein ; Irit Rasooly ; Wanczyk Phillips ; Mark Mai ; Adam Dziorny ; Levon Utidjian ; Anthony Luberti ; Jill Posner ; Rebecca Tenney-Soeiro ; Chris Bonafide

Improving Electronic Inpatient Progress Notes Using Voice: Results from the VGEENS Project ...... 155 Thomas H. Payne ; Andrew Markiel ; William D. Alonso ; Ross J. Lordon ; Kevin Lybarger ; Meliha Yetisgen ; Jennifer M. Zech ; Andrew A. White

Text Mining Radiology Reports for Deep Learning Radiology Images...... 157 Yifan Peng ; Xiaosong Wang ; Le Lu ; Bagheri Mohammadhadi ; Ronald Summers ; Zhiyong Lu

Towards a Generalized 6 Month Mortality Risk Model ...... 159 Andrew Placona ; Shantanu Phatakwala ; Becky Yamarik ; Neal O'Hara

Linking Resident Behavior to Health Conditions in an Eldercare Monitoring System ...... 161 Mihail Popescu ; Andrew L. Craver ; Lorraine Phillips ; Richelle J. Koopman ; Laurel Despins ; Gregory L. Alexander ; Marilyn Rantz

Identifying Potentially Missing Hierarchical Relations in SNOMED CT based on Lexical Features – Impact of Synonyms and Lexico-syntactic Constraints...... 163 Satyajeet Raje ; Olivier Bodenreider

Selecting and Refining the Characteristics of a Virtual Nurse for a Technology-Assisted Hospital-to-Home Care Transition Intervention in the Veterans Health Administration ...... 165 Lorilei M. Richardson ; Jessica Lipschitz ; Timothy P. Hogan ; Stephanie L. Shimada ; Bridget Smith ; Steven R. Simon ; Amy Rubin ; Bonnie Wakefield ; Peter Kaboli ; Jeydith Gutierrez Perez ; Paul A. Heidenreich ; Shuo Zhou ; Zachary Berwaldt ; Lin Shi ; Timothy Bickmore ; Thomas K. Houston

Information Retrieval for Biomedical Datasets: The 2016 bioCADDIE Challenge ...... 167 Kirk Roberts ; Anupama E. Gururaj ; Xiaoling Chen ; Saeid Pournejati ; Trevor Cohen ; William R. Hersh ; Dina Demner- Fushman ; Lucila Ohno-Machado ; Hua Xu

Association of BMI and Obesity Genetic Risk Score with Surgical Procedures Through a Procedure-wide Association Study...... 169 Jamie R. Robinson ; Zongyang Mou ; Lisa Bastarache ; Wei-Qi Wei ; Robert J. Carroll ; Joshua C. Denny

Deep Recurrent Neural Networks Identify Transgender Patients...... 171 Joseph D. Romano ; Kenrick Cato ; Rami Vanguri ; Nicholas P. Tatonetti

Development and Validation of a Continuously Age-Adjusted Measure of Patient Condition for Hospitalized Children Using the Electronic Medical Record ...... 173 Michael J. Rothman ; Joseph J. Tepas ; Andrew J. Nowalk ; Joan M. Rimar ; Albert Marchetti ; Allen Hsiao

Can Emergency Department Provider Notes Help Achieve More Dynamic Clinical Decision Support?...... 175 Justin F. Rousseau ; Ivan Ip ; Ali S. Raja ; Jeremiah D. Schuur ; Ramin Khorasani

Using mHealth to Monitor Asthma Symptoms Between Visits...... 177 Robert S. Rudin ; Christopher H. Fanta ; Zachary Predmore ; Eyal Zimlichman ; Kevin W. Kron ; Maria Edelen ; David Bates

Rationale and Design for the Duke Connected Care Predictive Modeling Pilot with a Medicare Shared Savings Program Population...... 178 Shelley A. Rusincovitch ; Ricardo Henao ; Michael Gao ; Lawrence Carin ; Ursula Rogers ; N. B. Neely ; Mary Schilder ; Daniel Costello ; Eugenie Komives ; Erich Huang

Dr. Babel Fish: A Machine Translator to Simplify Providers' Language ...... 180 Tarek Sakakini ; Renato F. Azevedo ; Victor Sadauskas ; Kuangxiao Gu ; Yang Zhang ; Suma Bhat ; Daniel Morrow ; Mark Hasegawa-Johnson ; Thomas S. Huang ; Ann M. Willemsen-Dunlap ; Donald J. Halpin ; James F. Graumlich

DeepPhe - A Natural Language Processing System for Extracting Cancer Phenotypes from Clinical Records ...... 182 Guergana Savova ; Eugene Tseytlin ; Sean Finan ; Melissa Castine ; Timothy A. Miller ; Olga Medvedeva ; David Harris ; Harry Hochheiser ; Chen Lin ; Girish Chavan ; Rebecca Jacobson

Novel Approaches to Identifying Rare Diseases Using Electronic Health Record Data, Mabry Syndrome as an Example ...... 184 Prabhu R. Shankar ; Rachel Logan ; Allison Foley ; Hong Li

The Variation in Patient Portal Access for Adolescents in the United States: How Different Medical Centers Manage their Adolescent Access...... 186 Marianne Sharko ; Lauren Wilcox ; Matthew K. Hong ; Jessica S. Ancker

Assessing Usability of the D2Refine Platform for Harmonization and Standardization of Clinical Study Data Dictionaries...... 188 Deepak K. Sharma ; Kevin Peterson ; Guoqian Jiang

Rule-Based Criteria for Recommending Algorithms and Visualization Techniques for Biomedical Data Analysis...... 190 Leslie Sim ; Charlotte Cheng ; Ajay Shah ; Srisairam Achuthan

Personal Health Information Management in the Virtual Home: A New Taxonomy for a New Perspective ...... 192 Catherine A. Smith ; Yuqi He ; Gail R. Casper

Discordances Between Patient-Reported Family History and Family Histories in EHR...... 194 Jung Hoon Son ; Chunhua Weng

Implementing NLP-based Point-of-care CDS Drives Adherence to Evidence-based Clinical Pathways...... 196 Srinivasan Suresh ; Gabriella Butler ; Andrew Buchert ; Amy Urban ; Curtis Stratman ; Nancy Zimmerman ; James A. Colbert

A Probabilistic Scoring Model to Evaluate Providers Regarding Continuity of Care from a Relational Perspective...... 198 Kazim Topuz ; Scott Shepherd ; William D. Paiva ; Dursun Delen ; Krista Schumacher ; Shrie Raam Sathyanarayanan ; Mehmet B. Yildirim

Retrospective and Prospective Evaluations of the System for Hospital Adaptive Readmission Prediction and Management (SHARP) for All-Cause 30-Day Pediatric Readmission Prediction ...... 200 Fuchiang Tsui ; Victor M. Ruiz ; Amie J. Barda ; Ye Ye ; Gabriella Butler ; Srinivasan Suresh ; Andrew H. Urbach

Developing Computable Phenotypes of Pediatric Chronic Conditions in PEDSnet...... 202 Levon Utidjian ; Ritu Khare ; Hanieh Razzaghi ; Amanda Dempsey ; Michelle Denburg ; Chris Forrest ; Charles Bailey

Clinical Workflow Visualization: Representation of Clinician Activity from Location Tracking Data ...... 204 Akshay Vankipuram ; Stephen Traub ; Vimla L. Patel

Using EHR and HIE Data to Identify Patients’ Need for Services That Address the Social Determinants of Health ...... 206 Joshua R. Vest ; Shaun Grannis ; Jennifer L. Williams ; Dawn Haut ; Nir Menachemi

A Conceptual Model of Personal Health Informatics for Chronic Illness ...... 208 Lisa M. Vizer ; Jordan Eschler ; Bon Mi Koo ; James Ralston ; Wanda Pratt

The LOINC/RSNA Radiology Playbook: A Unified Terminology for Radiology Procedures ...... 210 Daniel J. Vreeman ; Ken Wang ; Chris Carr ; Beverly Collins ; Swapna Abhyankar ; Jamalynne Deckard ; Clement J. McDonald ; Daniel Rubin ; Curtis Langlotz

Impact of Clinician Experience on Machine Learned Clinical Order Patterns...... 212 Jason K. Wang ; Alejandro Schuler ; Nigam Shah ; Jonathan H. Chen

Interactive Medical Word Sense Disambiguation with Instance and Feature Labeling...... 214 Yue Wang ; Kai Zheng ; Hua Xu ; Qiaozhu Mei

Real-Time Queries of Millions of Patients Using Probabilistic Sketches...... 216 Griffin M. Weber

Clinical Code Set Engineering for Reusing EHR Data for Research: A Review ...... 218 Richard Williams ; Evangelos Kontopantelis ; Iain E. Buchan ; Niels Peek

Development and Evaluation of a Novel User Interface for Reviewing Clinical Microbiology Results...... 220 Adam Wright ; Pamela M. Neri ; Skye Aaron ; Thu-Trang Hickman ; Francine L. Maloney ; Daniel A. Solomon ; Dustin S. McEvoy ; Angela Ai ; Kevin W. Kron ; Gianna Zuccotti

Detecting Body Location Modifiers of Disorders in Clinical Texts via Sequence Labeling...... 222 Jun Xu ; Yonghui Wu ; Yaoyun Zhang ; Hua Xu

Using Logistic Regression to Verify Completeness of Electronic Health Records for Infant Mortality Analysis...... 224 Luge Yang ; Jose D. Posada ; Hoah-Der Su ; Lingyun Shi ; Mi Fan ; Fuchiang Tsui

High-throughput Phenotyping Via Denoised Normal Mixture Transformation ...... 226 Sheng Yu ; Yumeng Ma ; Jessica L. Gronsbell ; Katherine P. Liao ; Tianrun Cai ; Ashwin Ananthakrishnan ; Vivian Gainer ; Susanne Churchill ; Peter Szolovits ; Shawn N. Murphy ; Isaac Kohane ; Tianxi Cai

Predicting Non-Small Cell Lung Cancer Diagnosis and Prognosis by Fully Automated Microscopic Pathology Image Features...... 228 Kun-Hsing Yu ; Ce Zhang ; Gerald J. Berry ; Russ B. Altman ; Christopher Ré ; Daniel Rubin ; Michael Snyder

Criteria2Query: Automatically Transforming Clinical Research Eligibility Criteria Text to OMOP Common Data Model (CDM)-based Cohort Queries ...... 230 Chi Yuan ; Patrick B. Ryan ; Yixuan Guo ; Peng Jin ; Tian Kang ; Chunhua Weng

Revision of Order Sets Using Experts’ Knowledge and Data-Driven Evidence...... 232 Yiye Zhang ; Richard Trepp ; Jorge M. Luna ; David Vawdrey ; Victoria Tiase

Subtyping Parkinson’s Disease with Recurrent Neural Network Models ...... 234 Xi Zhang ; Jian Liang ; Cao Xiao ; Yize Zhao ; Fei Wang

Assessing Electronic Health Record Readability ...... 236 Jiaping Zheng ; Hong Yu

Acute Kidney Injury in the Intensive Care Unit: Timing and Detection ...... 238 Leming Zhou ; Valerie J. Watzlaf ; Christopher M. Keener ; Dilhari Dealmeida ; Rebecca S. Desensi ; Emily Foldes ; Gilles Clermont ; John A. Kellum

Bridging the Gap Between Direct Patient Outreach in the Community and Clinical Information Access: Next Step in Effective Nationwide Clinical Trials ...... 240 Lindsay Zimmerman ; Shazia Sathar ; Charon Gladfelter ; Faraz S. Ahmad ; Alejandra Onate ; Lindsey Cook ; Shelly Sital ; Jasmin Phua ; Paris Davis ; Helen Margellos-Anast ; David Meltzer ; Tamar Polonsky ; Raj Shah ; Satyender Goel ; Abel N. Kho

The Impact of Human Microbiome on Precision Medicine...... 242 Alexander V. Alekseyenko ; Lita M. Proctor ; Paul Carlson ; Scott A. Jackson ; Connie Chen

Redesigning the “Choice Architecture” of the EHR to Reduce Clinical Decision Support Burden ...... 245 Jessica S. Ancker ; Sameer Malhotra ; Yiye Zhang ; Adam Cheriff

The Good, The Bad, and The Ugly of Deploying and Adopting Machine Learning Based Models in Clinical Practice ...... 248 Yin Aphinyanaphongs ; David Holmes ; Berkman Sahiner ; Parsa Mirhaji ; Michael Draugelis

Problem List 2.0...... 251 Joel R. Buchanan ; William Galanter ; Duwayne L. Willett ; Adam Wright

Social Determinants of Health: Applied Informatics Approaches Incorporating Context into Care ...... 254 Michael Cantor ; Hossein Estiri ; Rachel Gold ; Theresa Cullen

The Data and Research Center of the All of Us Research Program: Framework for a National Cohort Program and Research Opportunities...... 257 Robert J. Carroll ; Joshua Mandel ; Karthik Natarajan ; Scott Sutherland ; Joshua C. Denny

“My Work Will Surely Speak for Itself:” Visibility, Networking, and Self Promotion in Informatics...... 259 Wendy Chapman ; Murielle Beene ; Omolola Ogunyemi ; Genevieve B. Melton ; Laura K. Wiley

The Jordan Experience: The VistA Experience...... 262 Theresa Cullen ; Feras R. Kamal ; Nancy E. Anthracite

Opportunities and Challenges for Development, Implementation, and Investigation of Acute Care Patient Portals (ACPP): Recommendations from the ACPP Task Force...... 265 Anuj K. Dalal ; Sarah Collins ; Victoria Tiase ; Kristin O'Reilly ; Ryan Greyson

From Large-Scale Network Analytics to Clinical Solutions in OHDSI...... 268 Jon D. Duke ; George Hripcsak ; Patrick B. Ryan ; Nigam Shah

An Overview of Emerging Real-World OpenHIE Use Cases: Successes, Challenges, and Future Opportunities ...... 271 Shaun Grannis ; Eric-Jan Manders ; Frederick C. Leitner ; Annah Ngaruro ; Jack Bowie

Clinical Decision Support in the Era of Precision Medicine...... 274 Michael A. Grasso ; Barry H. Blumenfeld ; Joni L. Rutter ; Eliot L. Siegel ; Linda Wedemeyer

Successes and Challenges in Developing and Implementing Electronic Informed Consent Tools for Research ...... 277 Christopher A. Harle ; David R. Nelson ; Kenneth W. Goodman ; Elizabeth Bell

A Structured Approach to Measuring Individual Nurse’s Contribution in Patient Outcomes ...... 280 Ellen M. Harper ; Catherine H. Ivory ; Lisa A. Moon ; Amy Garcia

Clinical Informatics in Medical Education: Innovations from the AMA Accelerating Change in Medical Education Initiative...... 283 William R. Hersh ; Susan E. Skochelak ; Anderson Spickard ; Blaine Takesue ; Paul Gorman

The Best of Imaging Informatics Research 2017 ...... 285 William Hsu ; Charles E. Kahn

Can the Clinical Information Modeling Initiative (CIMI) Enable the Semantic Interoperability Promise of Fast Healthcare Interoperability Resources (FHIR®©)? ...... 286 Stanley M. Huff ; Claude Nanjo ; Julia Skapik

Big Data in the Intensive Care Unit...... 289 Andrew James ; Mohammad Adibuzzaman ; John Zaleski ; Peter J. Haug

Big Data to Knowledge (BD2K) and the Application of Metadata ...... 292 Guoqian Jiang ; Walter S. Campbell ; Timothy Clark ; Cui Tao ; Mark A. Musen

Enabling Knowledge-Driven Care at Scale through CDS Hooks and the FHIR Clinical Reasoning Module ...... 295 Kensaku Kawamoto ; Kevin Shekleton ; James Doyle ; Bryn Rhodes ; Howard R. Strasberg

Are EHRs “Overloading” Health Professionals? Issues, Advances and New Directions from Cognitive Science and Usability Engineering...... 298 Andre W. Kushniruk ; Elizabeth M. Borycki ; Yalini Senathirajah ; Darren Hudson

Accelerating Evidence Into Practice: AHRQ’s Clinical Decision Support Initiative ...... 301 Edwin Lomotan ; Dave Debronkart ; Barry H. Blumenfeld ; Robert McCready

A Spoonful of Structure Helps the Workload Go Down: Modeling Clinical Cognition in Inpatient Documentation Tools...... 304 Mark V. Mai ; Kai Zheng ; Eric D. Shelov ; Subha L. Airan-Javia ; Evan W. Orenstein

The PCORnet Learning Cycle ...... 307 Keith Marsolo ; Laura G. Qualls ; Bradley G. Hammill ; Jeffrey Brown ; Lesley H. Curtis

Getting Hooked on CDS: Toward an Open Standard Architecture for Clinical Decision Support in Leading Electronic Medical Records...... 310 Blackford Middleton ; Aziz A. Boxwala ; J. Marc Overhage ; James Doyle ; Mary Sung

Clinical Natural Language Processing in Languages Other Than English ...... 313 Aurelie Neveol ; Noemi Elhadad ; Sumithra Velupillai ; Hua Xu ; Guergana Savova

Innovation in Workflow Methods for Consumer Health Informatics...... 316 Mustafa Ozkaynak ; Rupa Valdez ; George Demiris ; Laurie L. Novak ; Yong Kyung Choi ; Charlene Weir

Engaging Patients with Health Technologies to Improve Quality of Care and to Reduce Preventable Harm...... 319 Wanda Pratt ; Patricia C. Dykes ; Ryan Greyson ; Cornelia M. Ruland ; David Bates

Latin American e-Health Programs and WHO/PAHO Planning Toolkit ...... 322 Yuri Quintana ; David Novillo-Ortiz ; Marcelo A. Lopetegui ; Mario Ruiz Cubillo ; Heimar F. Marin ; Paula Otero

Design and Implementation of a Structured Sequencing Report Format: A Multi-Stakeholder Perspective from eMERGE ...... 324 Luke V. Rasmussen ; Darren C. Ames ; Samuel J. Aronson ; Lawrence J. Babb ; Casey L. Overby

20 Years of Digital Pathology - An Overview of the Road Travelled and What is on the Horizon ...... 327 Joel Saltz ; Ashish Sharma ; Alexis Carter ; Liron Pantanowitz ; Tahsin Kurc

Evaluating Impacts of Patient-Facing eHealth Technologies: Connected Care in the Veterans Health Administration...... 330 Stephanie L. Shimada ; Timothy P. Hogan ; Thomas K. Houston ; Keith McInnes ; Neil C. Evans

Participatory Health Informatics for Data-Driven Precision Medicine...... 333 Jaideep Srivastava ; Luis Fernandez-Luque ; Fernando J. Martin-Sanchez ; Kenneth D. Mandl

Advancing Electronic Case Reporting (ECR) to Enable Public Health Disease Control and Emergency Response: Getting Into the Technical Weeds! ...... 336 Catherine J. Staes ; John Loonsk ; Kathryn Turner ; Noam H. Arzt ; Patina Zarcone

The State of Interoperability and Health Information Exchange in the U.S.: Advancing Steadily or Treading Water? ...... 339 Walter Sujansky ; Julia Adler-Milstein ; Ross Martin

Computational Phenotyping on Diverse Data Sources...... 342 Jimeng Sun ; Bradley Malin ; Abel N. Kho ; Mark W. Craven ; Joydeep Ghosh

Social and Behavioral Determinants of Health: Fundamental Informatics Challenges for Enriching Health IT Systems (Didactic Panel)...... 345 Albert Taylor ; Daniel J. Vreeman ; Christopher Alban ; Jon Puro

Optimizing Patient Care through Clinical Decision Support: Identification of Opportunities and Call to Action by the National Academy of Medicine...... 348 James Tcheng ; Kensaku Kawamoto ; Blackford Middleton ; Jonathan M. Teich ; Scott Weingarten

The Personal Journey – Informaticists Confront Their Own Health Issues ...... 351 Jessica Tenenbaum ; William E. Hammond ; Ross Koppel ; Michael Kamerick

And Now for Something Completely Different: Successful Career Transformations in Biomedical and Health Informatics ...... 353 Amy Y. Wang ; Douglas B. Fridsma ; Judy Murphy ; Chintan Patel ; Hillary Ross

Collaborative Pharming...... 356 Mark G. Weiner ; Jennifer Boehne ; Terese Kornet ; Ross Koppel

Current State of Visualization of EHR Data – What’s Needed? What’s Next?...... 359 Vivian L. West ; Hadi Kharrazi ; Dawn Dowding ; Jesus J. Caban ; Danny T. Wu

PCMEDICS: Peace Corps’ Home-Grown EMR...... 361 Thomas M. Wilkinson ; Shannon Behr DeNoble ; Kimberly Skrtic ; Monica D. Charles ; Lyndsey Knauf

Quality Assurance of NCI Thesaurus by Mining Structural-Lexical Patterns ...... 364 Rashmie Abeysinghe ; Michael A. Brooks ; Jeffery C. Talbert ; Licong Cui

Building an Informed Consent Tool Starting with the Patient: The Patient-Centered Virtual Multimedia Interactive Informed Consent (VIC)...... 374 Fuad Abujarad ; Sandra Alfano ; Tiffani J. Bright ; Sneha Kannoth ; Nicole Grant ; Matthew Gueble ; Peter Peduzzi ; Geoffrey Chupp

Big Data in Healthcare-- The Promises, Challenges and Opportunities from a Research Perspective: a Case Study with a Model Database...... 384 Mohammad Adibuzzaman ; Poching Delaurentis ; Jennifer Hill ; Brian D. Benneyworth

Applying the Concept of Nutrient-Profiling to Promote Healthy Eating and Raise Individuals’ Awareness of the Nutritional Quality of their Food...... 393 Mayda A. Alrige ; Samir Chatterjee ; Ernie Medina ; Jeje Noval

Open Globe Injury Patient Identification in Warfare Clinical Notes ...... 403 Emilia Apostolova ; Helen A. White ; Patty Morris ; David Eliason ; Tom Velez

Intelligent Word Embeddings of Free-Text Radiology Reports ...... 411 Imon Banerjee ; Sriraman Madhavan ; Roger Eric Goldman ; Daniel Rubin

Gap Analysis and Refinement Recommendations of Skin Alteration and Pressure Ulcer Enterprise Reference Models against Nursing Flowsheet Data Elements...... 421 Karen M. Bavuso ; Roberto A. Rocha ; Perry L. Mar ; Sarah Collins

Eliciting Values of Patients with Multiple Chronic Conditions: Evaluation of a Patient-centered Framework...... 430 Andrew B. Berry ; Catherine Lim ; Andrea L. Hartzler ; Tad Hirsch ; Evette Ludman ; Ed Wagner ; James Ralston

Improving the ‘Fitness for Purpose’ of Common Data Models through Realism Based Ontology ...... 440 Jonathan C. Blaisure ; Werner Ceusters

A Simulation Study on Handoffs and Cross-coverage: Results of an Error Analysis...... 448 Katherine Blondon ; Marzia Del Zotto ; Jessica Rochat ; Mathieu R. Nendaz ; Christian Lovis

Exhaustively Characterizing a Patient Cohort by Prevalence of EMR Facts: a Generalized, Vendor-Agnostic Method for Quality Control and Research...... 458 Alex F. Bokov ; Gail P. Olin ; Angela Bos ; Alfredo Tirado-Ramos ; Pamela Kittrell ; Carlayne E. Jackson

Nurse Generated EHR Data Supports Post-Acute Care Referral Decision Making: Development and Validation of a Two-step Algorithm ...... 465 Kathryn H. Bowles ; Sarah J. Ratcliffe ; Mary D. Naylor ; John H. Holmes ; Susan K. Keim ; Emilia Flores

Creating Clinical Fuzzy Automata with Fuzzy Arden Syntax ...... 475 Jeroen S. De Bruin ; Heinz Steltzer ; Andrea Rappelsberger ; Klaus-Peter Adlassnig deidentify ...... 485 Philipp Burckhardt ; Rema Padman

Mobile Apps for Mood Tracking: An Analysis of Features and User Reviews...... 495 Clara Caldeira ; Yu Chen ; Lesley Chan ; Vivian Pham ; Yunan Chen ; Kai Zheng

Combining Rules, Background Knowledge and Change Patterns to Maintain Semantic Annotations ...... 505 Silvio Domingos Cardoso ; Chantal Reynaud-Delaître ; Marcos Da Silveira ; Cedric Pruski

Detecting Evidence of Intra-abdominal Surgical Site Infections from Radiology Reports Using Natural Language Processing ...... 515 Alec B. Chapman ; Danielle Mowery ; Douglas S. Swords ; Wendy Chapman ; Brian T. Bucher

Deep Learning Solutions for Classifying Patients on Opioid Use ...... 525 Zhengping Che ; Jennifer St. Sauver ; Hongfang Liu ; Yan Liu

Automated Metabolic Phenotyping of Cytochrome Polymorphisms Using PubMed Abstract Mining ...... 535 Luoxin Chen ; Carol Friedman ; Joseph Finkelstein

Large-scale Analysis of Opioid Poisoning Related Hospital Visits in New York State ...... 545 Xin Chen ; Yu Wang ; Xiaxia Yu ; Elinor Schoenfeld ; Mary Saltz ; Joel Saltz ; Fusheng Wang

Determining Burden of Commuting for Treatment Using Online Mapping Services – A Study of Breast Cancer Patients...... 555 Alex C. Cheng ; Mia A. Levy

Predicting Inpatient Acute Kidney Injury over Different Time Horizons: How Early and Accurate? ...... 565 Peng Cheng ; Lemuel R. Waitman ; Yong Hu ; Mei Liu

Specifications of Clinical Quality Measures and Value Set Vocabularies Shift Over Time: A Study of Change through Implementation Differences ...... 575 Raja A. Cholan ; Nicole G. Weiskopf ; Doug Rhoton ; Nicholas Colin ; Rachel L. Ross ; Melanie N. Marzullo ; Bhavaya Sachdeva ; David A. Dorr

Doodle Health: A Crowdsourcing Game for the Co-design and Testing of Pictographs to Reduce Disparities in Healthcare Communication ...... 585 Carrie Christensen ; Douglas F. Redd ; Erica Lake ; Jean Shipman ; Heather Aiono ; Roger Altizer ; Bruce E. Bray ; Qing T. Zeng

Evaluation of a Systematic Methodology to Detect in Near Real-time Performance Changes During Electronic Health Record System Implementations: A Longitudinal Study...... 595 Tiago K. Colicchio ; Guilherme Del Fiol ; Gregory J. Stoddard ; Scott P. Narus

Evolution of an Implementation-Ready Interprofessional Pain Assessment Reference Model ...... 605 Sarah A. Collins ; Karen M. Bavuso ; Mary Swenson ; Christine Suchecki ; Perry L. Mar ; Roberto A. Rocha

Towards Analytics of the Patient and Family Perspective: A Case Study and Recommendations for Data Capture of Safety and Quality Concerns ...... 615 Brittany Couture ; Maureen B. Fagan ; Esteban Gershanik ; Catherine Yoon ; James Benneyan ; David Bates ; Sarah Collins

Calibration Drift Among Regression and Machine Learning Models for Hospital Mortality...... 625 Sharon E. Davis ; Thomas A. Lasko ; Guanhua Chen ; Michael E. Matheny

Does Level of Numeracy and Graph Literacy Impact Comprehension of Quality Targets? Findings from a Survey of Home Care Nurses ...... 635 Dawn Dowding ; David Russell ; Karyn Jonas ; Nicole Onorato ; Yolanda Barron ; Jacqueline Merrill ; Robert J. Rosati

Detection of Suicidality in Adolescents with Autism Spectrum Disorders: Developing a Natural Language Processing Approach for Use in Electronic Health Records ...... 641 Johnny Downs ; Sumithra Velupillai ; George Gkotsis ; Rachel Holden ; Maxim Kikoler ; Harry Dean ; Andrea Fernandes ; Rina Dutta

Secure and Trustable Electronic Medical Records Sharing using Blockchain ...... 650 Alevtina Dubovitskaya ; Zhigang Xu ; Samuel Ryu ; Michael Schumacher ; Fusheng Wang

Evaluation of Clinical Text Segmentation to Facilitate Cohort Retrieval ...... 660 Tracy Edinger ; Dina Demner-Fushman ; Aaron M. Cohen ; Steven Bedrick ; William R. Hersh

An Automated System for Categorizing Transthoracic Echocardiography Indications According to the Echocardiography Appropriate Use Criteria...... 670 Aaron S. Eisman ; Rory B. Weiner ; Elizabeth S. Chen ; Paul Stey ; Rishi K. Wadhera ; Aaron P. Kithcart ; Indra N. Sarkar

Hybrid Semantic Analysis for Mapping Adverse Drug Reaction Mentions in Tweets to Medical Terminology...... 679 Ehsan Emadzadeh ; Abeed Sarker ; Azadeh Nikfarjam ; Graciela Gonzalez

Word-of-Mouth Innovation: Hypothesis Generation for Supplement Repurposing based on Consumer Reviews ...... 689 Jung-Wei Fan ; Yves A. Lussier

Improving Common Ground Development in Surgical Training through Talk and Action...... 696 Yuanyuan Feng ; Helena M. Mentis

Routine Self-tracking of Health: Reasons, Facilitating Factors, and the Potential Impact on Health Management Practices...... 706 Mayara Figueiredo ; Clara Caldeira ; Yunan Chen ; Kai Zheng

A Cross-Sectional Study of Prominent US Mobile Health Applications: Evaluating the Current Landscape ...... 715 Pierre-Antoine Fougerouse ; Mobin Yasini ; Guillaume Marchand ; Oliver O. Aalami

Achieving Logical Equivalence Between SNOMED CT and ICD-10-PCS Surgical Procedures ...... 724 Kin Wah Fung ; Julia Xu ; Filip Ameye ; Arturo Romero-Gutiérrez ; Arabella D’Havé

Toward Automated Pre-Biopsy Thyroid Cancer Risk Estimation in Ultrasound...... 734 Alfiia Galimzianova ; Sean M. Siebert ; Aya Kamaya ; Terry S. Desser ; Daniel Rubin

Effectiveness of a Cloud-Based EHR Clinical Decision Support Program for Body Mass Index (BMI) Screening and Follow-up ...... 742 Shruti Gangadhar ; Nam Nguyen ; James Pesuit ; Alina Bogdanov ; Lee Kallenbach ; Jessica Ken ; Joe Vasey ; Richard Loomis

VOLUME 2

The "Safety Net" of Community Care: Leveraging GIS to Identify Geographic Access Barriers to Texas Family Planning Clinics ...... 750 Lori Gawron ; Warren Pettey ; Andrew M. Redd ; Ying Suo ; David Turok ; Adi V. Gundlapalli

Quantifying the Impact of Trainee Providers on Outpatient Clinic Workflow Using Secondary EHR Data...... 760 Isaac H. Goldstein ; Michelle R. Hribar ; Sarah Read-Brown ; Michael F. Chiang

Inferring Clinical Correlations from EEG Reports with Deep Neural Learning ...... 770 Travis R. Goodwin ; Sanda M. Harabagiu

A Configurational Analysis of Risk Patterns for Predicting the Outcome After Traumatic Brain Injury ...... 780 Niku Gorji ; Zador Zsolt ; Simon Poon

Using Process Mining Techniques to Study Workflows in a Pre-operative Setting ...... 790 A. Grando ; Danielle Groat ; Stephanie K. Furniss ; Joshua Nowak ; Regina Gaines ; David R. Kaufman ; Karl Poterack ; Richard Helmers ; Tim Miksch

Sharing Clinical Notes with Hospitalized Patients via an Acute Care Portal...... 800 Lisa V. Grossman ; Ruth M. Masterson Creber ; Susan Restaino ; David Vawdrey

When Synonyms Are Not Enough: Optimal Parenthetical Insertion for Text Simplification ...... 810 Yang Gu ; Gondy Leroy ; David Kauchak

Understanding the Patterns of Health Information Dissemination on Social Media During the Zika Outbreak...... 820 Xinning Gui ; Yue Wang ; Yubo Kou ; Tera L. Reynolds ; Yunan Chen ; Qiaozhu Mei ; Kai Zheng

StressHacker: Towards Practical Stress Monitoring in the Wild with Smartwatches...... 830 Tian Hao ; Kimberly N. Walter ; Marion J. Ball ; Hung-Yang Chang ; Si Sun ; Xinxin Zhu

A Mobile System for the Improvement of Heart Failure Management: Evaluation of a Prototype ...... 839 Sarah C. Haynes ; Katherine K. Kim

Comparing and Contrasting A Priori and A Posteriori Generalizability Assessment of Clinical Trials on Type 2 Diabetes Mellitus ...... 849 Zhe He ; Arturo Gonzalez-Izquierdo ; Spiros Denaxas ; Andrei Sura ; Yi Guo ; William Hogan ; Elizabeth Shenkman ; Jiang Bian

Bar Charts Detection and Analysis in Biomedical Literature of PubMed Central ...... 859 Ying He ; Xiaohan Yu ; Yangjing Gan ; Tujin Zhu ; Shengwu Xiong ; Jing Peng ; Lun Hu ; Guang Xu ; Xiaohui Yuan

Evaluating the Effectiveness of Auditing Rules for Electronic Health Record Systems ...... 866 Monica Hedda ; Bradley Malin ; Chao Yan ; Daniel Fabbri

Mining Electronic Health Records to Extract Patient-Centered Outcomes Following Prostate Cancer Treatment...... 876 Tina Hernandez-Boussard ; Panayotis Kourdis ; Tina Seto ; Michelle Ferrari ; Daniel Rubin ; Douglas W. Blayney ; James Brooks

The Dependence of Machine Learning on Electronic Medical Record Quality...... 883 Long V. Ho ; David Ledbetter ; Melissa D. Aczon ; Randall C. Wetzel

Classifying Acute Ischemic Stroke Onset Time using Deep Imaging Features ...... 892 King Chung Ho ; William Speier ; Suzie M. El-Saden ; Corey W. Arnold

Use of the Multidimensional Health Locus of Control to Predict Information-Seeking Behaviors and Health- Related Needs in Pregnant Women and Caregivers...... 902 Lauren E. Holroyd ; Shilo H. Anders ; Jamie R. Robinson ; Gretchen P. Jackson

Accuracy and Completeness of Clinical Coding Using ICD-10 for Ambulatory Visits...... 912 Jan Horsky ; Elizabeth A. Drucker ; Harley Ramelson

Evaluating and Improving an Outpatient Clinic Scheduling Template Using Secondary Electronic Health Record Data ...... 921 Michelle R. Hribar ; Sarah Read-Brown ; Leah G. Reznick ; Michael F. Chiang

A First Step Towards Behavioral Coaching for Managing Stress: A Case Study on Optimal Policy Estimation with Multi-stage Threshold Q-learning ...... 930 Xinyu Hu ; Pei-Yun S. Hsueh ; Ching-Hua Chen ; Keith Diaz ; Ying-Kuen K. Cheung ; Min Qian

Framing Electronic Medical Records as Polylingual Documents in Query Expansion...... 940 Edward W. Huang ; Sheng Wang ; Doris J. Lee ; Runshun Zhang ; Baoyan Liu ; Xuezhong Zhou ; Chengxiang Zhai

Extracting Actionable Recommendations for Modifying Enterprise Order Set Templates from CPOE Utilization Patterns...... 950 Nathan C. Hulse ; Jaehoon Lee

Replicability, Reproducibility, and Agent-based Simulation of Interventions...... 959 R. Stanley Hum ; Samantha Kleinberg

Thinking Together: Modeling Clinical Decision-Support as a Sociotechnical System...... 969 Mustafa I. Hussain ; Tera L. Reynolds ; Fatemeh E. Mousavi ; Yunan Chen ; Kai Zheng

Differential Data Augmentation Techniques for Medical Imaging Classification Tasks...... 979 Zeshan Hussain ; Francisco Gimenez ; Darvin Yi ; Daniel Rubin

Measuring Workload Demand of Informatics Systems with the Clinical Case Demand Index...... 985 M. Sriram Iyengar ; Deevakar Rogith ; Jose F. Florez-Arango

Real-time Mortality Prediction in the Intensive Care Unit ...... 994 Alistair E. Johnson ; Roger Mark

User Requirements for an Electronic Medical Records System for Oncology in Developing Countries: A Case Study of Uganda ...... 1004 Johnblack K. Kabukye ; Sabine Koch ; Ronald Cornet ; Jackson Orem ; Maria Hägglund

Mechanism-based Pharmacovigilance Over the Life Sciences Linked Open Data Cloud ...... 1014 Maulik R. Kamdar ; Mark A. Musen

Initializing and Growing a Database of Health Information Technology (HIT) Events by Using TF-IDF and Biterm Topic Modeling...... 1024 Hong Kang ; Zhiguo Yu ; Yang Gong

Overcoming the Maternal Care Crisis: How Can Lessons Learnt in Global Health Informatics Address US Maternal Health Outcomes? ...... 1034 Suranga N. Kasthurirathne ; Burke Mamlin ; Saptarshi Purkayastha ; Theresa Cullen

Modes of De-identification...... 1044 Mehmet Kayaalp

Comparison of Algorithm Advice for Post-acute Care Referral to Usual Clinical Decision-making: Examination of 30-day Acute Healthcare Utilization ...... 1051 Susan K. Keim ; Kathryn H. Bowles

Exploiting Unlabeled Texts with Clustering-based Instance Selection for Medical Relation Classification ...... 1060 Youngjun Kim ; Ellen Riloff ; Stephane Meystre

Leveraging Existing Corpora for De-identification of Psychiatric Notes Using Domain Adaptation ...... 1070 Hee Jin Lee ; Yaoyun Zhang ; Kirk Roberts ; Hua Xu

A Framework for Data Quality Assessment in Clinical Research Datasets ...... 1080 Kathleen Lee ; Nicole G. Weiskopf ; Jyotishman Pathak

A Computational Framework for a Digital Surveillance and Response Tool: Application to Avian Influenza...... 1090 Eva K. Lee ; Yifan Liu ; Ferdinand H. Pietz

Exploring the Design and Role of Mobile Apps for Healthcare Providers to Find Teratogenic Information...... 1100 Lily Lei ; Vishwas Shetty ; Karan Gupta ; Janine Polifka ; Glen Markham ; Sarah Albee ; Carol Collins ; Gary Hsieh

X Marks the Spot: Mapping Similarity Between Clinical Trial Cohorts and US Counties...... 1110 Matthew C. Lenert ; Dara Mize ; Colin G. Walsh

Environmental Reservoirs of Nosocomial Infection: Imputation Methods for Linking Clinical and Environmental Microbiological Data to Understand Infection Transmission ...... 1120 Julia Lensing ; Ketki Vilankar ; Hyojung Kang ; Donald Brown ; Amy Mathers ; Laura Barnes

Bootstrap-based Feature Selection to Balance Model Discrimination and Predictor Significance: A Study of Stroke Prediction in Atrial Fibrillation...... 1130 Xiang Li ; Zhaonan Sun ; Xin Du ; Haifeng Liu ; Gang Hu ; Guotong Xie

A Multi-scale U-Net for Semantic Segmentation of Histological Images from Radical Prostatectomies...... 1140 Jiayun Li ; Karthik V. Sarma ; King Chung Ho ; Arkadiusz Gertych ; Beatrice S. Knudsen ; Corey W. Arnold

A hybrid Neural Network Model for Joint Prediction of Medical Presence and Period Assertions in Clinical Notes...... 1149 Rumeng Li ; Abhyuday Jagannatha ; Hong Yu

SpindleSphere: A Web-based Platform for Large-scale Sleep Spindle Analysis and Visualization...... 1159 Xiaojin Li ; Licong Cui ; Shiqiang Tao ; Ningzhou Zeng ; Guo-Qiang Zhang

Representation of Social History Factors Across Age Groups: A Topic Analysis of Free-Text Social Documentation...... 1169 Elizabeth A. Lindemann ; Elizabeth S. Chen ; Yan Wang ; Steven J. Skube ; Genevieve B. Melton

Automatically Detecting Likely Edits in Clinical Notes Created Using Automatic Speech Recognition ...... 1179 Kevin Lybarger ; Mari Ostendorf ; Meliha Yetisgen

Improving Quality of Follow-Up Imaging Recommendations in Radiology ...... 1189 Thusitha Mabotuwana ; Christopher S. Hall ; Joel S. Tieder ; Martin L. Gunn

Evidence of Progress in Making Nursing Practice Visible Using Standardized Nursing Data: a Systematic Review...... 1198 Tamara G. R. Macieira ; Madison Smith ; Nicolle Davis ; Yingwei Yao ; Diana J. Wilkie ; Karen Dunn Lopez ; Gail Keenan

Detection of Adverse Drug Reactions Using Medical Named Entities on Twitter...... 1208 Andrew Mackinlay ; Hafsah Aamer ; Antonio Jimeno Yepes

Usability and Learnability of RxUniverse, an Enterprise-Wide App Prescribing Platform Used in an Academic Tertiary Care Hospital...... 1218 Sonya Makhni ; Rivelle Zlatopolsky ; Farah Fasihuddin ; Misael Aponte ; Jason Rogers ; Ashish Atreja

Deep Learning Meets Biomedical Ontologies: Knowledge Embeddings for Epilepsy ...... 1226 Ramon Maldonado ; Travis R. Goodwin ; Michael A. Skinner ; Sanda M. Harabagiu

Extracting Healthcare Quality Information from Unstructured Data...... 1236 Shervin Malmasi ; Naoshi Hosomura ; Lee-Shing Chang ; C. J. Brown ; Stephen Skentzos ; Alexander Turchin

A Novel Application of Point-of-sales Grocery Transaction Data to Enhance Community Nutrition Monitoring ...... 1246 Hiroshi Mamiya ; Erica E. Moodie ; David Buckeridge

Point of Care Research: Integrating Patient-generated Data Into Electronic Health Records for Clinical Trials...... 1255 Sara Marceglia ; Pierluigi D'Antrassi ; Marco Prenassi ; Lorenzo Rossi ; Sergio Barbieri

Fast and Accurate Metadata Authoring Using Ontology-Based Recommendations...... 1265 Marcos Martínez-Romero ; Martin J. O’Connor ; Ravi D. Shankar ; Maryam Panahiazar ; Debra Willrett ; Attila Levente Egyedi ; Olivier Gevaert ; John Graybeal ; Mark A. Musen

Developing a Concussion Assessment Mhealth App for Certified Athletic Trainers...... 1275 Scott P. McGrath ; Melanie L. McGrath ; Dhundy Bastola

Does a Community-Engaged Health Informatics Platform Facilitate Resource Connectivity? An Evaluation Framework...... 1285 Mari Millery ; Alejandra Aguirre ; Rita Kukafka

Distinction Between Medical and Non-medical Usages of Short Forms in Clinical Narratives...... 1295 Sungrim Moon ; Donna Ihrke ; Yuqun Zeng ; Hongfang Liu

Supervised Learning Methods for Predicting Healthcare Costs: Systematic Literature Review and Empirical Evaluation...... 1305 Mohammad Amin Morid ; Kensaku Kawamoto ; Travis Ault ; Josette Dorius ; Samir E. Abdelrahman

The Role of Surface, Semantic and Grammatical Features on Simplification of Spanish Medical Texts: A User Study ...... 1315 Partha Mukherjee ; Gondy Leroy ; David Kauchak ; Brianda Armenta Navarrete ; Damian Y. Romero Diaz ; Sonia Colina

Identification of Clinically Meaningful Plasma Transfusion Subgroups Using Unsupervised Random Forest Clustering ...... 1325 Che Ngufor ; Matthew A. Warner ; Dennis Murphree ; Hongfang Liu ; Rickey E. Carter ; Curtis B. Storlie ; Daryl J. Kor

Value of Genetics-informed Drug Dosing Guidance in Pregnant Women: A Needs Assessment with Obstetric Healthcare Providers at Johns Hopkins ...... 1335 Casey L. Overby ; Phillip Thompkins ; Harold Lehmann ; Christopher G. Chute ; Jeanne Sheffield

Evaluation of Semantic Web Technologies for Storing Computable Definitions of Electronic Health Records Phenotyping Algorithms ...... 1345 Vaclav Papez ; Spiros Denaxas ; Harry Hemingway

Tracking Health Related Discussions on Reddit for Public Health Applications ...... 1355 Albert Park ; Mike Conway

Mining Hierarchies and Similarity Clusters from Value Set Repositories ...... 1365 Kevin J. Peterson ; Guoqian Jiang ; Scott Brue ; Feichen Shen ; Hongfang Liu

A Conceptual Measurement Model for eHealth Readiness: A Team Based Perspective...... 1375 James Phillips ; Simon Poon ; Dan Yu ; Mary Lam ; Monique Hines ; Melissa Brunner ; Emma Power ; Melanie Keep ; Tim Shaw ; Leanne Togher

Challenges with Collecting Smoking Status in Electronic Health Records ...... 1385 Fernanda Polubriaginof ; Hojjat Salmasian ; David A. Albert ; David K. Vawdrey

Design and Evaluation of a Web-based Decision Support Tool for District-level Disease Surveillance in a Low- resource Setting ...... 1394 Meenal Pore ; David M. Sengeh ; Purity Mugambi ; Nuri Purswani ; Tom Sesay ; Anna Lena Arnold ; Ralph Myers ; Anh-Minh A. Tran

Stage-Specific Survivability Prediction Models across Different Cancer Types...... 1404 Elham Sagheb Hossein Pour ; Rohit Kate

An Open Source Tool for Game Theoretic Health Data De-Identification...... 1413 Fabian Prasser ; James Gaupp ; Zhiyu Wan ; Weiyi Xia ; Yevgeniy Vorobeychik ; Murat Kantarcioglu ; Klaus A. Kuhn ; Bradley Malin

Leveraging Health Information Exchange to Construct a Registry for Traumatic Brain Injury, Spinal Cord Injury and Stroke in Indiana...... 1423 Saurabh Rahurkar ; Timothy D. McFarlane ; Jane Wang ; Sarah Hoover ; Flora Hammond ; Jacob Kean ; Brian Dixon

Stakeholder Use and Feedback on Vaccination History and Clinical Decision Support for Immunizations Offered by Public Health ...... 1433 Sripriya Rajamani ; Aaron Bieringer ; Similoluwa Sowunmi ; Miriam H. Muscoplat

Formative Evaluation of CareNexus: a Tool for the Visualization and Management of Care Teams of Complex Pediatric Patients...... 1441 Pallavi Ranade-Kharkar ; Chuck Norlin ; Guilherme Del Fiol

Understanding Patient Questions about their Medical Records in an Online Health Forum: Opportunity for Patient Portal Design...... 1451 Tera L. Reynolds ; Nida Ali ; Emma McGregor ; Tricia O'Brien ; Christopher Longhurst ; Andrew L. Rosenberg ; Scott Rudkin ; Kai Zheng

A Semantic Parsing Method for Mapping Clinical Questions to Logical Forms...... 1461 Kirk Roberts ; Braja G. Patra

Is the Application of SNOMED CT Concept Model Sufficiently Quality Assured?...... 1471 Jean-Marie Rodrigues ; Stefan Schulz ; Bassim Mizen ; Alan L. Rector ; Sofyane Serir

Mining the Literature for Genes Associated with Placenta-mediated Maternal Diseases ...... 1481 Laritza M. Rodriguez ; Stephanie M. Morrison ; Kathleen Greenberg ; Dina Demner-Fushman

Electronic Surveillance For Catheter-Associated Urinary Tract Infection Using Natural Language Processing ...... 1490 Patrick C. Sanger ; Marion Granich ; Robin Olson-Scribner ; Rupali Jain ; William B. Lober ; Ann Stapleton ; Paul Pottinger

The Problems of Realism-Based Ontology Design: a Case Study in Creating Definitions for an Application Ontology for Diabetes Camps ...... 1500 James C. Schuler ; Werner Ceusters

Reconciliation of Multiple Guidelines for Decision Support: a Case Study on the Multidisciplinary Management of Breast Cancer Within the DESIREE Project...... 1510 Brigitte Séroussi ; Gilles Guézennec ; Jean-Baptiste Lamy ; Naiara Muro ; Nekane Larburu ; Booma Devi Sekar ; Coralie Prebet ; Jacques Bouaud

Harnessing Biomedical Natural Language Processing Tools to Identify Medicinal Plant Knowledge from Historical Texts...... 1520 Vivekanand Sharma ; Wayne Law ; Michael J. Balick ; Indra N. Sarkar

VOLUME 3

The Effect of Neighborhood Disadvantage on Diabetes Prevalence...... 1530 Lincoln Sheets ; Greg Petroski ; Julie Jaddoo ; Yan Barnett ; Chris Barnett ; Laura E. Henderson Kelley ; Vaishnavi Raman ; Amy J. Kind ; Jerry C. Parker

Leveraging Collaborative Filtering to Accelerate Rare Disease Diagnosis...... 1537 Feichen Shen ; Sijia Liu ; Yanshan Wang ; Liwei Wang ; Naveed Afzal ; Hongfang Liu

Utilizing Smartphone-Based Machine Learning in Medical Monitor Data Collection: Seven Segment Digit Recognition...... 1547 Varun N. Shenoy ; Oliver O. Aalami

Leveraging Clinical Time-Series Data for Prediction: A Cautionary Tale...... 1554 Eli Sherman ; Hitinder Gurm ; Ulysses Balis ; Scott R. Owens ; Jenna Wiens

Secondary Use of Patients’ Electronic Records (SUPER): An Approach for Meeting Specific Data Needs of Clinical and Translational Researchers...... 1564 Evan Sholle ; Joseph Kabariti ; Stephen B. Johnson ; John Leonard ; Jyotishman Pathak ; Vinay I. Varughese ; Curtis Cole ; Thomas R. Campion

Disease-Specific Integration of Omics Data to Guide Functional Validation of Genetic Associations...... 1572 Maya Shumyatcher ; Rui Hong ; Jessica Levin ; Blanca E. Himes

Data Visualization of Home Care Admission Nurses' Decision-Making...... 1580 Paulina S. Sockolow ; Yushi Yang ; Ellen J. Bass ; Kathryn H. Bowles ; Annika Holmberg ; Sheryl L. Potashnik

Current State of Electronic Consent Processes in Behavioral Health: Outcomes from an Observational Study...... 1590 Hiral Soni ; Adela Grando ; Anita C. Murcko ; Mike Bayuk ; Pramod Bharadwaj Chandrashekhar ; Madhumita Mukundan ; Meredith Abrams ; Marcela P. Aliste ; Megan Hiestand ; Julia Varkey ; Wentao Zhou ; Caroline Horrow ; Michael Saks ; Richard Sharp ; Mary Jo Whitfield ; Mark Callesen ; Christina Dye ; Darwyn Chern

Modeling Contextual Knowledge for Clinical Decision Support ...... 1600 Margarita Sordo ; Priyaranjan Tokachichu ; Christopher J. Vitale ; Saverio M. Maviglia ; Roberto A. Rocha

Reducing the Toxicity Risk in Antibiotic Prescriptions by Combining Ontologies with a Multiple Criteria Decision Model ...... 1608 Souhir Ben Souissi ; Mourad Abed ; Lahcen Elhiki ; Philippe Fortemps ; Marc Pirlot

A Data-Driven Method for Generating Robust Symptom Onset Indicators in Disease Registry Data...... 1618 Zhaonan Sun ; Ying Li ; Soumya Ghosh ; Yu Cheng ; Amrita Mohan ; Cristina Sampaio ; Jianying Hu

Designing Decision-support Technologies for Patient-generated Data in Type 1 Diabetes ...... 1628 Si Sun ; Kaitlin L. Costello

Causal Phenotyping for Susceptibility to Cardiotoxicity from Antineoplastic Breast Cancer Medications...... 1638 Deyu Sun ; Gyorgy Simon ; Steven J. Skube ; Anne Blaes ; Genevieve B. Melton ; Rui Zhang

A Multi-task Framework for Monitoring Health Conditions via Attention-based Recurrent Neural Networks ...... 1648 Qiuling Suo ; Fenglong Ma ; Giovanni Canino ; Jing Gao ; Aidong Zhang ; Pierangelo Veltri ; Agostino Gnasso

Physician Information Needs in Managing Delirium...... 1658 Teresa Taft ; Stacey Slager ; Scott D. Nelson ; Charlene Weir

Facilitating Cohort Discovery by Enhancing Ontology Exploration, Query Management and Query Sharing for Large Clinical Data Repositories...... 1668 Shiqiang Tao ; Licong Cui ; Xi Wu ; Guo-Qiang Zhang

A Scalable Privacy-preserving Data Generation Methodology for Exploratory Analysis...... 1678 Jaideep Vaidya ; Basit Shafiq ; Muazzam Asani ; Nabil R. Adam ; Xiaoqian Jiang ; Lucila Ohno-Machado

ProvCaRe Semantic Provenance Knowledgebase: Evaluating Scientific Reproducibility of Research Studies ...... 1688 Joshua Valdez ; Matthew Kim ; Michael Rueschman ; Vimig Socrates ; Satya S. Sahoo ; Susan Redline

Using a Community-Engaged Health Informatics Approach to Develop a Web Analytics Research Platform for Sharing Data with Community Stakeholders...... 1698 Karen H. Wang ; Luis N. Marenco ; Johanna Elumn Madera ; Jenerius Aminawung ; Emily Wang ; Kei Cheung

Drug Repositioning for Prostate Cancer: Using a Data-driven Approach to Gain New Insights...... 1707 Quanqiu Wang ; Rong Xu

Combining Mechanism-based Prediction with Patient-based Profiling for Psoriasis Metabolomics Biomarker Discovery ...... 1717 Quanqiu Wang ; Thomas McCormick ; Nicole Ward ; Kevin Cooper ; Ruzica Conic ; Rong Xu

SCOTCH: Secure Counting Of encrypTed genomiC Data Using a Hybrid Approach ...... 1727 Chenghong Wang ; Yichen Jiang ; Feng Chen ; Noman Mohammed ; Xiaoqian Jiang ; Md. Momin A. Aziz ; Md. Nazmus Sadat ; Shuang Wang

Classifying Clinical Trial Eligibility Criteria to Facilitate Phased Cohort Identification Using Clinical Data Repositories ...... 1737 Amy Y. Wang ; William J. Lancaster ; Matthew Wyatt ; Luke V. Rasmussen ; Daniel Fort ; James J. Cimino

What Are They Trying to Do?: An Analysis of Action Identities in Using Electronic Documentation in an EHR ...... 1747 Charlene R. Weir ; Catherine Staas ; Stacey Slager ; Teresa Taft ; Valiammai Chidambaram ; Heidi Kramer ; Bruce E. Bray ; Seneca Perri Moore

Interactive Visualization and Exploration of Patient Progression in a Hospital Setting ...... 1756 Wathsala Widanagamaachchi ; Yarden Livnat ; Peer-Timo Bremer ; Scott L. Duvall ; Valerio Pascucci

Residence, Living Situation, and Living Conditions Information Documentation in Clinical Practice...... 1766 Tamara J. Winden ; Elizabeth S. Chen ; Yan Wang ; Elizabeth A. Lindemann ; Genevieve B. Melton

Towards Precision Informatics of Pharmacovigilance: OAE-CTCAE Mapping and OAE-based Representation and Analysis of Adverse Events in Patients Treated with Cancer Drugs ...... 1776 Meiu Wong ; Rebecca Racz ; Edison Ong ; Yongqun He

Implementation of a Medication Reconciliation Assistive Technology: A Qualitative Analysis...... 1785 Theodore B. Wright ; Kathleen Adams ; Victoria L. Church ; Mimi Ferraro ; Scott Ragland ; Anthony Sayers ; Stephanie Tallett ; Travis Lovejoy ; Joan S. Ash ; Patricia Holahan ; Blake J. Lesselroth

Clinical Named Entity Recognition Using Deep Learning Models ...... 1795 Yonghui Wu ; Min Jiang ; Jun Xu ; Degui Zhi ; Hua Xu

Using EHR Audit Trail Logs to Analyze Clinical Workflow: A Case Study from Community-based Ambulatory Clinics...... 1803 Danny T. Y. Wu ; Nikolas Smart ; Elizabeth Ciemins ; Holly J. Lanham ; Curt Lindberg ; Kai Zheng

Learning Doctors’ Medicine Prescription Pattern for Chronic Disease Treatment by Mining Electronic Health Records: A Multi-Task Learning Approach ...... 1811 Eryu Xia ; Jing Mei ; Guotong Xie ; Xuejun Li ; Zhibin Li ; Meilin Xu

Predicting Changes in Pediatric Medical Complexity Using Large Longitudinal Health Records ...... 1821 Yanbo Xu ; Mohammad Taha Bahadori ; Elizabeth Searles ; Michael Thompson ; Javier Tejedor-Sojo ; Jimeng Sun

Identifying High Health Care Utilizers Using Post-Regression Residual Analysis of Health Expenditures from a State Medicaid Program...... 1831 Chengliang Yang ; Chris Delcher ; Elizabeth Shenkman ; Sanjay Ranka

Classification of Hepatocellular Carcinoma Stages from Free-text Clinical and Radiology Reports ...... 1841 Wen-Wai Yim ; Sharon W. Kwan ; Guy Johnson ; Meliha Yetisgen

Talking About My Care: Detecting Mentions of Hormonal Therapy Adherence Behavior in an Online Breast Cancer Community ...... 1851 Zhijun Yin ; Wei Xie ; Bradley Malin

Initial Usability Evaluation of a Knowledge-Based Population Health Information System: The Population Health Record (PopHR) ...... 1861 Mengru Yuan ; David Buckeridge ; Guido Powell ; Maxime Lavigne ; Anya Okhmatovskaia

Contralateral Breast Cancer Event Detection Using Nature Language Processing ...... 1868 Zexian Zeng ; Xiaoyu Li ; Sasa Espino ; Ankita Roy ; Kristen Kitsch ; Susan Clare ; Seema Khan ; Yuan Luo

Towards Supporting Patient Decision-making In Online Diabetes Communities...... 1876 Jing Zhang ; Rebecca A. Marmor ; Jina Huh

Can SNOMED CT Changes Be Used as a Surrogate Standard for Evaluating the Performance of Its Auditing Methods? ...... 1886 Guo-Qiang Zhang ; Yan Huang ; Licong Cui

Barriers, Facilitators, and Solutions to Optimal Patient Portal and Personal Health Record Use: A Systematic Review of the Literature ...... 1896 Jane Y. Zhao ; Buer Song ; Edwin Anand ; Diane Schwartz ; Mandip Panesar ; Gretchen P. Jackson ; Peter L. Elkin

Identifying Falls Risk Screenings Not Documented with Administrative Codes Using Natural Language Processing ...... 1906 Vivienne J Zhu ; Tina Walker ; Robert W. Warren ; Peggy Jenny ; Stephane Meystre ; Leslie A. Lenert

Spark-MCA: Large-scale, Exhaustive Formal Concept Analysis for Evaluating the Semantic Completeness of SNOMED CT ...... 1914 Wei Zhu ; Guo-Qiang Zhang ; Licong Cui

User-Centered Design and Usability Assessment of an EHR Integrated Automated SOFA Calculator App ...... 1924 Christopher A. Aakre ; Jaben Kitson ; Man Li ; Vitaly Herasevich

Cranky Comments: Detecting Clinical Decision Support Malfunctions Through Free-Text Override Reasons ...... 1925 Skye Aaron ; Adam Wright

Characterizing a Learning Curve for Annotating Data for Training and Validation of Natural Language Processing Systems ...... 1926 Glenn L. Abastillas ; Spencer Morris ; Jessica A. Boten ; Tumenbayar Tumurchudur ; Kinjal Vora ; Paul Fearn

Extraction of Patient Temporal Patterns and Clusters from Clinical Data ...... 1927 Samir E. Abdelrahman ; Julio Facelli ; Bruce E. Bray ; Rashmee Shah ; Guilherme Del Fiol

Dissemination of HIV, HCV and STD Clinical Evidence to Primary Care Providers – An Analysis of User Profiles and Course Evaluations of a Statewide Online Clinical Education Program ...... 1928 Meredith Abrams ; Dongwen Wang

A Resource for Clinical Semantic Textual Similarity ...... 1929 Naveed Afzal ; Yanshan Wang ; Feichen Shen ; Liwei Wang ; Hongfang Liu

Multiple Perspectives on Ambulatory Test Result Follow-up Culture ...... 1930 Angela Ai ; Sonali Desai ; Andrea Shellman ; Adam Wright

Releasing De-Identified Clinical, Imaging, and Genomic Data from the VA to External Repositories for the APOLLO Network ...... 1931 Samuel Ajjarapu ; Frank Meng ; Danne C. Elbers ; Nhan V. Do ; Robert Hall ; Karen E. Pierce-Murray ; Luis E. Selva ; Beth Katcher ; Brett R. Johnson ; Andrew J. Zimolzak ; Corri Dedomenico ; Mary Brophy ; Louis Fiore

Pathology Information Extraction in Bladder Cancer Surveillance ...... 1932 Patrick R. Alba ; Scott L. Duvall ; Terri E. Workman ; Florian Schroeck ; Olga V. Patterson

Pseudomonas Aeruginosa: Assessing Trends in Antimicrobial Resistance Between 2006 and 2012...... 1933 Tochi C. Amadi ; Craig W. Johnson

Harmonizing User-defined Phenotypic Variables using Latent Semantic Analysis (LSA) to Improve Data Discoverability in dbGaP...... 1934 Liz Amos ; Satyajeet Raje ; Masato Kimura ; Preeti G. Kochar ; Victoria Wilder ; Ben Busby

Decoding the Behavior Change Techniques in Mobile Health Apps ...... 1935 Marcy G. Antonio ; Karen L. Courtney ; Judith T. Matthews

Reference Range Number Lines Preferred by Latino Adults for Display of Clinical and Patient-Reported Outcome Data ...... 1936 Adriana Arcia

Relationship between the Breadth of Patient Engagement Health IT Features Adopted and Hospital Financial Strength ...... 1937 O. Elijah Asagbra ; Darrell Burke

Integrating a Patient Display Into the Primary Care Exam Room to Improve Patient Engagement ...... 1938 Onur Asan ; Paul Iglar ; Jeanne T. Tyszka ; Rabia Copuroglu

Healthcare Claims Data - Challenges in Acquisition and Analysis ...... 1939 Bhanu Bahl ; Daniel Runt ; Nealia Khan ; Douglas Macfadden

Local Causal Networks Discover Predictive Cytokine Biomarkers of Scleroderma ...... 1940 Ali S. Bakhtiari ; Galina S. Bogatkevich ; Alexander V. Alekseyenko

Patient Generated Health Data Governance at a Cancer Center ...... 1941 Erdeta Bani ; Rimma Belenkaya ; Olga Strachna ; Daniel Stein ; Peter Stetson

The Time is Right for Clinical Data Platforms that Reduce Clinician Time Reviewing Patient Care Data Elements: Emerge as a Proof of Concept...... 1942 Denise Barchas ; Angela Lipshutz ; Kathleen Liu ; Kathleen Turner ; Charlotte Garwood ; Kelly Timothy ; Amie Lencioni ; Michael A. Gropper ; Hildy M. Schell-Chaple

Distributed Health Data Networks: Extending the PopMedNetTM Informatics Infrastructure to Expand Existing Query Functionality to Target New Data Sources...... 1943 Kimberly Barrett ; Jessica Malenfant ; Kyle Erickson ; Adam Paczuski ; Zachary Wyner ; Chayim Herzig-Marx ; Jeffrey Brown

Comparative Analysis of Intravenous to Oral Transitions at Two Tertiary Care Hospitals in the U.S. and Switzerland...... 1944 Patrick E. Beeler ; David Bates ; Juerg Blaser

A Simple and Efficient Method for the Management of Multiple Electronic Health Record-Driven Phenotype Projects ...... 1945 Cosmin A. Bejan ; Joshua C. Denny

Implementation of a Knowledge Base Driven Perioperative Metrics Framework and Governance Program ...... 1946 Rimma Belenkaya ; Olga Strachna ; Stromblad Christopher ; Kinjal Shah ; Hyok-Hee Yoo ; Natalia Shapiro ; Alexander Tanchoco ; Marina Kerpelev ; Ilya Sher ; Jonathan Wills ; Shai Ahmed ; Peter Stetson ; Daniel Stein

Honoring Patient’s Data Sharing Preferences: Implementation Challenges ...... 1947 Elizabeth Bell ; Diana Guijarro ; Imho Jang ; Wenhong Zhu ; Tyler Bath ; Gwangnoh Yun ; Masud Rahman ; Chao Jiang ; Xiaoqian Jiang ; Lucila Ohno-Machado ; Hyeoneui Kim

Self-Service Cohort Discovery across Five Academic Health Centers: Usage and User Evaluations of the University of California Research eXchange...... 1948 Douglas S. Bell ; Lisa Dahm ; Nick Anderson ; Ida Sim ; Pralav P. Dessai ; Marianne Zachariah ; Lucila Ohno-Machado

Barriers to Prompting Beta Blocker Titration in Heart Failure at the Point of Care...... 1949 Paige Benally ; Michael Smith ; Charnetta R. Brown ; Natalie Kelly ; Jose Nativi ; Charlene Weir ; Salim Virani ; Megha Kalsy ; Jennifer H. Garvin

Implementation and Adherence Evaluation of Intrusive Alerts for Adjusting Dose to Renal Function...... 1950 Francisco M. Bernabeu ; Susana Hernandez Caffot ; Nadime Noe Sufan ; Fabiana Ellena ; Bayan V. Khorsandnia

Development of a Large-scale, Whole Body CT Image Databsase ...... 1951 Shamsi Daneshvari Berry ; Heather J. Edgar

Identification of Patient Subgroups in Metastatic Breast Cancer Patients Based on Somatic Copy Number Alterations: A Bipartite Network Analysis...... 1952 Suresh K. Bhavnani ; Archana Ayyaswami ; Tianlong Chen ; Jeremy L. Warner

Implementing a Hash-based Privacy-Preserving Entity Resolution Tool in the OneFlorida Clinical Data Research Network ...... 1953 Jiang Bian ; Andrei Sura ; Gloria P. Lipori ; Yi Guo ; François Modave ; Zhe He ; Elizabeth Shenkman ; William Hogan

Validation of Standard Diabetes Identification within Identification Methods in Electronic Health Records ...... 1954 Katie E. Bickett ; Timothy D. Imler

RxNorm Concept History Service ...... 1955 Olivier Bodenreider ; Lee Peters

Does Semantic Tag Usage in SNOMED CT Match its Concept Hierarchy?...... 1956 Jonathan P. Bona

Electronic Health Records and their Modules: Impacts on Clinical Practice and Patient Care...... 1957 Elizabeth M. Borycki ; Andre W. Kushniruk ; Yalini Senathirajah

Leveraging Large-Scale Computing for Population Information Integration, Analysis, and Modeling ...... 1958 Jessica A. Boten ; Donna R. Rivera ; Madhumita Myneni ; Georgia Tourassi ; Tanmoy Bhattacharya ; Ana Paula De Oliveira Sales ; Thomas Brettin ; Paul Fearn ; Lynne Penberthy

Detection of Opioid-Dependence: Extracting Opioid Use Patterns from Patient Secure Messages ...... 1959 Lina Bouayad ; Dezon Finch ; Stephen L. Luther

Toward a Reliable and Interoperable Public Repository for Natural Product Drug Interaction Study Data ...... 1960 Richard D. Boyce ; Isabelle Ragueneau-Majlessi ; Jingjing Yu ; Jessica Sontheimer ; Chris Kinsella ; Mathias Brochhausen ; John Judkins ; Bruce Pinkleton ; Rebecca L. Cooney ; Mary Paine ; Jeannine McCune

Leveraging Electronic Medical Record Data for Research with Consistency and Efficiency: A Use Case in an Ongoing Obstetrics Clinical Study ...... 1961 Robert L. Bradford ; Karen Dorman ; Anna Maria Siega-Riz ; Alison Suebe ; Wanda Nicholson ; Kiira Lyons

Enabling Collaboration for Building High Quality, Sustainable and Scalable National Health Information Systems in Resource-limited Settings...... 1962 Pascal Brandt ; Jan Flowers ; William B. Lober

Modular Health Informatics Architecture for a Patient Centered mHealth Diabetes Intervention ...... 1963 Ian M. Brooks ; Justin Gatwood ; Bonnie L. Binkley ; Emmanuel Villa ; Jennifer Featherston ; James E. Bailey

TNF-alpha Use as a Risk Factor for Lymphoma in Rheumatoid Arthritis Patients Using the Virtual Research Data Center...... 1964 Gregory T. Brown ; Fabricio S. Kury ; Clement J. McDonald

Knowledge-Enriched Data: Realizing the Riches of Our Data ...... 1965 Matthew Burton ; Amy Knopp ; Davide Sottara ; James Buntrock ; Daryl J. Kor ; Terri Glaze ; Meghan Sandberg ; Scott Finnesgard

Physicians Behavior with a Non – Overriding Alert Prescriptions in a CDS Dosing System Developed in Argentina...... 1966 María S. Hernandez Caffot ; Carolina Vogt ; Solana Muñoz Fernandez ; Francisco M. Bernabeu ; Bayan V. Khorsandnia

Improving EHR Chart Review Efficiency Via Semantic Similarity Assessment ...... 1967 Tianrun Cai ; Andrew Beam ; Stephanie Chan ; Jacqueline Honerlaw ; Yichi Zhang ; David Gagnon ; Kelly Cho ; Michael Gaziano ; Katherine P. Liao ; Tianxi Cai ; Yuk-Lam Ho

Exploring Novel Graphical Representations of Clinical Data in a Learning EMR...... 1968 Luca Calzoni ; Gilles Clermont ; Gregory F. Cooper ; Shyam Visweswaran ; Harry Hochheiser

A Natural Language Processing System for Biomedical Dataset Retrieval...... 1969 Xiaoling Chen ; Jun Xu ; Jingqi Wang ; Anupama E. Gururaj ; Lucila Ohno-Machado ; Hua Xu

The Access of Bone Marrow Transplant Patients to Online Support ...... 1970 Ming-Yuan Chih ; Jennifer A. Christian ; Kang Namkoong ; Miranda Hatfield ; Meghan Johnson ; Rancie Hannah ; Jamie Studts ; Robin Vanderpool ; Gerhard C. Hildebrandt

Usability Evaluation of a Prototype mHealth App for Symptom Self-Management in Underserved Persons Living with HIV ...... 1971 Hwayoung Cho ; Hestia Rojas ; Casey Fulmer ; Rebecca Schnall

Evaluation of OMOP Vocabulary on Transplant Registry Data...... 1972 Sylvia Cho ; Margaret Sin ; Karthik Natarajan

Use of Storyboarding in the Development of a Pain Management Mobile App: A Case Study...... 1973 Jeeyae Choi

Validating a Single-Item Stress Scale for mHealth Interventions...... 1974 Wonchan Choi ; Sherry L. Pagoto ; Edwin D. Boudreaux ; Bengisu Tulu

Creating a Framework to Standardize Data Extraction from Electronic Health Record Systems for Researchers and to Support Distributed Queries ...... 1975 Mera Choi ; Nagesh Bashyam ; Daniella Meeker ; Eliel Oliveira

OMOP on FHIR as an Enabler for Analytics-As-A-Service ...... 1976 Myung Choi ; Richard Starr ; Jon Duke

Reproducibility in Biomedical Natural Language Processing...... 1977 Kevin B. Cohen ; Aurelie Neveol ; Jingbo Xia ; Negacy Hailu ; Cyril Grouin ; Lawrence E. Hunter ; Pierre Zweigenbaum

The Impact of Health IT Adoption: Are We Measuring the Right Outcomes? ...... 1978 Tiago K. Colicchio ; Guilherme Del Fiol ; Watson A. Bowes ; Julio Facelli ; Debra Scammon ; Scott P. Narus

ProjectFlow: Configurable Clinical Trial Management with Enterprise Data Integration and Point-of-Care Study Support ...... 1979 Ryan C. Cornia ; Nilla Majahalme ; Danne C. Elbers ; Svitlana Dipietro ; Brian R. Ivie ; Brad Adams ; Ramana Seerapu ; Valmeek Kudesia ; Scott L. Duvall

An International Comparison of High-priority and Low-priority Drug-drug Interactions in Different Electronic Health Record Systems ...... 1980 Pieter Cornu ; Shobha Phansalkar ; Diane L. Seger ; Insook Cho ; Sarah K. Pontefract ; Alexandra Robertson ; David Bates ; Sarah P. Slight

Automated Image Quality Assessment for Fundus Images in Retinopathy of Prematurity...... 1981 Aaron S Coyner ; Ryan Swan ; Jayashree Kalpathy-Cramer ; Sang Jin Kim ; John P. Campbell ; Karyn Jonas ; Susan Ostmo ; R. V. P. Chan ; Michael F. Chiang

Where’s the Data and Where Do I Start? Assessing Stakeholder Needs for Effective Use of Institutional Data ...... 1982 Chandrea Culbreath ; Maria Souden ; Melissa Nemon ; Holli Kreinbring ; Margaret Gonsoulin ; Denise M. Hynes

The Capture of Social and Behavioral Determinants of Health in Electronic Health Records...... 1983 Theresa Cullen ; Katie Allen ; Sara Armson ; Anna Roberts ; Daniel J. Vreeman

Using Environmental Sensors to Estimate Users Activity ...... 1984 Dorothy W. Curtis ; Mike Wang

Mixed Methods Approach for Understanding Clinical Workflow ...... 1985 Ioana Danciu ; Kim M. Unertl ; Stuart Weinberg ; Daniel Fabbri

Structured Data Capture (SDC) ...... 1986 Farrah Darbouze ; William E. Hammond ; Richard Moldwin ; Sue Dubman ; Matthew F. Chudy

Evaluating Health Kiosk Technology as an Enabler of Shared Decision Making ...... 1987 Selena Davis ; Karen L. Courtney ; Judith T. Matthews

Testing an Explainer Animation for Public Health Education ...... 1988 Jeffrey Day ; Anne Altemus

CTB: A Custom Taxonomy Builder for Named Entity Extraction ...... 1989 Dina Demner-Fushman ; Willie Rogers

Improving the Quality of Clinical Data Extracted from Text...... 1990 Daniel Denhalter ; Olga V. Patterson ; Brian D. Robison ; Scott L. Duvall

Blockchain for Privacy and Security: The Case of Health Informatics ...... 1991 Gupreet Dhillon ; Kane Smith ; Monica C. Tremblay

The Development of the Research Precision Oncology Program Data Repository (PODR) in the Veterans Affairs Healthcare System...... 1992 Nhan V. Do ; Karen E. Pierce-Murray ; Edmund C. Peirce ; Corri Dedomenico ; Frank Meng ; Danne C. Elbers ; Beth Katcher ; Robert Hall ; Andrew Zimolzak ; Samuel Ajjarapu ; Colleen Shannon ; Sara Turek ; Brett R. Johnson ; Nathanael Fillmore ; Mary Brophy ; Louis Fiore

Reasons for Rework in Clinical Data Provisioning: A Root-Cause Analysis ...... 1993 Amanda L. Do ; Ruby Wan ; Robert W. Follett ; Marianne Zachariah ; Douglas S. Bell

Physician Conception of Patient Frailty in Cardiac Care Decisions ...... 1994 Kristina Doing-Harris ; Rashmee Shah ; Yijun Shao ; Bruce E. Bray ; Qing Zeng-Treitler ; Jennifer H. Garvin ; Charlene Weir

Heuristics for Evaluation of Dashboard Visualizations ...... 1995 Dawn Dowding ; Jacqueline Merrill

Curbside Consultation in the Virtual Healthcare Environment: A Mixed Methods Analysis of Cases Referred to Occupational Medicine Specialists in the Veterans Health Administration...... 1996 Jennifer Lipkowitz Eaton ; Amir Mohammad

Implementation of an Informatics Solution to Improve Management of Pathology Specimens for the VA Precision Oncology Program...... 1997 Danne C. Elbers ; Robert Hall ; Beth Katcher ; Svitlana Dipietro ; Sung Feng-Chi ; Sergey Goryachev ; Karen E. Pierce-Murray ; Corri Dedomenico ; Lauren Macmullen ; Helene Garcon ; Nhan V. Do ; Louis Fiore

Distributed Health Data Networks: A Rapid, Systematic Approach to Verifying Machine-Generated Queries Within Different Systems...... 1998 Kyle Erickson ; Jessica Malenfant ; Kimberly Barrett ; Adam Paczuski ; Chayim Herzig-Marx ; Jeffrey Brown

Leveraging an Enterprise Data Warehouse to Support Clinical Workflow: Targeted Notification of Pathology Results...... 1999 Michael Eubank ; Janice Sung ; Krishna Juluru

Visual Query Combinators for BioMedical Query Mediation...... 2000 Clark Evans ; Charles H. Tirrell ; Oleksiy Golovko ; Andrey Popp ; Jason Simeone ; Kyrylo Simonov

Clinician, EHR Alerts, and Patient Outcome in Primary Care Setting ...... 2001 Mohammad A. Faysel ; Tameca Miller

Using EHR Clinical Decision Support to Improve Emergency Department Care for Children with High Risk Asthma...... 2002 Daria F. Ferro ; Levon Utidjian ; Joseph Zorc

Honest Broker Process Using System-Wide Permanent Research Identifiers ...... 2003 Robert W. Follett ; Theona Tacorda ; Javier Sanz ; Douglas S. Bell

Crowdsourcing Evidence-Based Medicine (EBM) ...... 2004 Paul Fontelo ; Fang Liu

Medication Errors Generated When Using Computerized Provider Order Entry Systems in Pediatrics: A Systematic Review ...... 2005 Niamh E. Forde ; Clare L. Tolley ; Katherine L. Coffey ; Dean F. Sittig ; Joan S. Ash ; Andrew K. Husband ; David Bates ; Sarah P. Slight

Improving Ambulatory Care Patient Safety for Community Acquired Pneumonia through a New Electronic Clinical Decision Support ...... 2006 Maysoun Freij ; Prashila Dullabh ; Richard Shiffman ; Nitu Kashyap ; Rajdeep Brar ; Katherine Donaldson ; Sarah Islam ; Richard Ricciardi

Using Systems Engineering Methods to Identify, Assess, and Mitigate Preventable Harm as part of a Patient Safety Learning Laboratory ...... 2007 Theresa E. Fuller ; Anuj K. Dalal ; Dominic Breuer ; Pamela M. Neri ; David Bates ; James Benneyan

The Presence of Highly Similar Notes Within the MIMIC-III Dataset...... 2008 Rodney A. Gabriel ; Sanjeev Shenoy ; Tsung-Ting Kuo ; Julian McAuley ; Chun-Nan Hsu

Feasibility of State Public Health Agencies Linking National Program of Cancer Registries and Birth Certificate Data: Outcomes and Lessons Learned...... 2009 Roland E. Gamache ; Timothy J. Carney ; Mary Ann Cooney ; Emily H. Moore

An Exploratory Study of Older Adults’ Strengths, Needs, and Outcomes Using Electronic Health Record Data in a Senior Living Community ...... 2010 Grace Gao ; Madeleine Kerr ; Ruth Lindquist ; Chih-Lin Chi ; Karen A. Monsen

Leveraging Crowdsourcing to Help Classify Social Media Data for Medical and Patient Safety Insights...... 2011 Alex Gartland ; Arooj Akhtar ; Richard Le ; Greg Powell

Clinicians’ Perceptions of Usefulness of the PubMed4Hh App for Clinical Decision-Making at the Point of Care...... 2012 Kyungsook Gartrell ; Caitlin W. Brennan ; Fang Liu ; Gwenyth R. Wallen ; Paul Fontelo

Development of Clinical Information Displays in the Emergency Department: Cognitive Support to Improve Patient Safety ...... 2013 Carolina Gatica ; Carolina Diaz ; Juan Pablo Salazar ; Mario Barbé ; Po-Yin Yen ; Marcelo A. Lopetegui

A Flexible Computational Neuroinformatics Workflow for Computing Functional Networks in Epilepsy Neurological Disorder ...... 2014 Arthur L. Gershon ; Bilal Zonjy ; Curtis Tatsuoka ; Kaushik Ghosh ; Satya S. Sahoo ; Samden D. Lhatoo

A Data-driven Method for the Early Identification of Diabetes and Prediabetes...... 2015 Travis R. Goodwin ; Michael E. Bowen ; Sanda M. Harabagiu

Vitals Risk Index: A Simplified Pediatric Early Warning Index that Relies Solely on Objective Measures...... 2016 Tyler Gorham ; Steven W. Rust ; Jing Yang ; James Lin ; Richard Hoyt ; Swan Bee Liu ; Jeffrey Hoffman ; Tensing Maa ; Yungui Huang ; Simon Lin

State-level Adoption of National Guidelines for Norovirus Outbreaks in Healthcare Settings: Implications for Decision Support...... 2017 Carl J. Grafe ; Catherine J. Staes ; Kensaku Kawamoto ; Matthew Samore ; Scott Evans

Critical Appraisal of Models for Prediction of Readmission (CAMPR): A Quality Tool to Assess Models that Predict Hospital Readmissions...... 2018 Lisa V. Grossman ; Rollin R. Reeder ; Colin G. Walsh ; Devan Kansagara ; David Vawdrey ; Hojjat Salmasian

A Machine Learning-Based Approach for Identifying Atopic Dermatitis in Adults from Electronic Health Records ...... 2019 Erin N. Gustafson ; Al'Ona Furmanchuk ; Jennifer A. Pacheco ; Firas Wehbe ; Kathryn Jackson ; Abel Kho ; William Thompson ; Jonathan Silverberg

Inpatient Perspectives and Information Needs for Error Prevention ...... 2020 Shefali Haldar ; Sonali R. Mishra ; Ari H. Pollack ; Wanda Pratt

Development of a VA Clinical Trial Matching Application (POP CTMatch) to Enhance Clinical Ability to Bring Trials to Veterans ...... 2021 Robert B. Hall ; Elly J. Cohen ; Thomas P. Bechtold ; Susan L. Colen ; Karen E. Pierce-Murray ; Nhan V. Do ; Louis Fiore

Understanding Use of Health IT to support Treatment of Youth with Substance Abuse Disorders using Evidence- Based Practices ...... 2022 Saira N. Haque ; Shellery Ebron ; Erin Mallonee ; Laura Dunlap

The Effect of Relational Coordination on Handoff Routines: A Case Study...... 2023 Saira N. Haque ; Carsten Østerlund ; Lawrence M. Fagan

From Scoping Review to Metadata: An Evidence-Based Approach to Identifying Informed Consent Metadata for Biorepositories ...... 2024 Marcelline Harris ; Frank Manion ; Hsing-Yi Song ; Yongqun He ; Muhammad F. Amith ; Cui Tao

Development & Implementation of a Clinical Decision Support Tool for Familial Hypercholesterolemia...... 2025 Ali Hasnie ; Pedro J. Caraballo ; Robert R. Freimuth ; Iftikhar J. Kullo

Screening the Contribution of Medical Reports to Electronic Diagnostic Systems ...... 2026 Peter J. Haug ; Jeffrey P. Ferraro ; Nathan C. Dean

Using Modular Reasoning to Improve Classification Performance of the SNOMED CT Ontology With Added Description Logic Features...... 2027 Robert R. Hausam

Facilitators and Barriers to PHR Adoption Experienced by Pediatric Primary Care Providers...... 2028 Kisha H. Hawthorne ; Anthony Luberti ; Patricia Lee ; Erin Sladek

A Visual Analysis Tool of Qualitative Eligibility Criteria of Clinical Studies...... 2029 Zhe He ; Zhiwei Chen ; Sarah Mixon ; Jiang Bian

Quality Improvement Dashboard to Monitor Oral Manifestations of Dysglycemic Patients ...... 2030 Harshad Hegde ; Alok Sagar Panny ; Rajesh H. Koralkar ; Amit Acharya

Extracting Condition-action Statements in Medical Guidelines ...... 2031 Hossein Hematialam ; Wlodek Zadrozny

Semantic Association for Literature Based Discovery ...... 2032 Sam Henry ; Bridget McInnes

An Assessment of the Contribution of Technology on Documentation Practices in an EHR: Evaluation of the Introduction of Two Computer-based Tools in a Clinical Research Environment ...... 2033 David Herion ; Matt Fred

The Experience of Students Building an Effective Clinical Data Warehouse for a Free, Student-Run Clinic...... 2034 Matthew C. Hess ; Steve Layfield ; Timothy I. Kennell ; Seung Park

Upstream Detection of Clinical Decision Support Malfunctions ...... 2035 Thu-Trang T. Hickman ; Lewis Silletto ; Adam Wright

Behavioral Health Provider Perspectives on Health Data Sharing ...... 2036 Megan Hiestand ; Adela Grando ; Anita Murcko ; Hiral Soni ; Julia Varkey ; Caroline Horrow ; Michael Saks ; Richard Sharp ; Mary Jo Whitfield ; Mark Callesen ; Christy Dye ; Darwyn Chern

A Unified Chart Review Tool Integrating OMOP CDM and Unstructured Data ...... 2037 Charity A. Hilton ; Jon Duke

Modeling the Cognitive Diagnostic Process, Mapping Factors Associated with Diagnostic Errors, and Analysis of Measures to Prevent Diagnostic Errors ...... 2038 Teruyoshi Hishiki ; Rie Ichikawa ; Jimpei Misawa ; Yukihiro Maeda ; Akiko Shibuya ; Yoshiaki Kondo

Data-driven Mobile Medical Immunization Clinic for Veterans ...... 2039 Christopher Hollweg ; Andrew Muth ; Valentin Rivish ; Pamela Garcia-Filion ; Hamed Abbaszadegan

Standardization of Prescribing Data in PCORnet: RxNorm Concept Unique Identifiers in Multi-Site Research...... 2040 Casie E. Horgan ; Jessica L. Sturtevant ; Charles Bailey ; Lindsey E. Petro ; Julia A. Fearrington ; Juliane S. Reynolds ; Jeffrey Brown ; Jason P. Block

Data Heterogeneity Among CMS Data Assets: Challenges and Opportunities for PCOR...... 2041 Lauren Hovey ; Rina Dhopeshwarkar ; Prashila Dullabh

A Dashboard to Help Clinicians Identify Hospitalized Pediatric Patients at High Risk of Medication Errors ...... 2042 Jonathan D. Hron

A System for Monitoring Stability, Usage and Data Completeness in OpenMRS Electronic Health Records in Rural Rwanda...... 2043 H. S. F. Fraser ; Michael Mugisha ; Janise K. Richards ; Wayne Chelliah ; Joseph Ngenzi ; Eric Gaju ; Aline Umubyeyi

Real-world Evidence for Phenotyping Chronic Diabetic Kidney Disease...... 2044 Lynn S. Huang ; Xufei Zheng ; Fang-Chi Hsu ; Jianzhao Xu ; Maggie Ng ; Donald Bowden ; Barry Freedman ; Jing Su

Semantic Analysis of a Nursing Home EHR for Sensor Data Annotation...... 2045 Zhongkai Huang ; Mihail Popescu

Annotation of Research Common Data Elements Using Clinical Terminologies ...... 2046 Vojtech Huser ; Cynthia Burke ; Minh-Diep Nguyen ; Liz Amos

Transformation of Disparate Terminology Standards to a Common Model ...... 2047 Eric Y. Hwang ; Soyun S. Choi

Unsupervised Analysis of Activity Patterns in Eldercare Monitoring ...... 2048 Omar Ibrahim ; Mihail Popescu ; James Keller

Clinical Informatics 101 Training in Family Medicine...... 2049 Tochi Iroku-Malize ; Barbara Keber

Linguistic Summarization of Sensor Data Leading to Health Events ...... 2050 Akshay Jain ; Mihail Popescu ; James Keller

Business Process Modeling in the Arden Syntax ...... 2051 Robert A. Jenders

MALTASE: A Mobile AppLication To Improve Patients’ Access to their Data Sharing PreferencE...... 2052 Chao Jiang ; Xiaoqian Jiang ; Shuang Wang ; Diana Guijarro ; Elizabeth Bell ; Imho Jang ; Gwangnoh Yun ; Masud Rahman ; Lucila Ohno-Machado ; Hyeoneui Kim

Teacher Evaluation and Its Correlated Factors: a Case Study of Introductory Health Informatics Education ...... 2053 Xia Jing ; Timothy Vickers ; Brian Phillips ; Kathy Jefford

Identifying Factors Associated with Problem List Omissions in Electronic Medical Records (EMR), to Assess Underdiagnosis in Obesity...... 2054 Akshat Kapoor ; Juhee Kim ; Xiaoming Zeng ; Andrew G. Anderson

Evolution of Research Topics in MEDLINE ...... 2055 Andrej Kastrin ; Thomas Rindflesch ; Dimitar Hristovski

Development and Implementation of Clinical Data Management Tecnology for Clinical Research ...... 2056 Shogo Kato ; Yoshihiko Morikawa ; Seiji Mitsui ; Takeshi Kuriyama ; Takahisa Ogasawara ; Kazuyuki Saito ; Naohisa Yahagi

Assessment of Clinical Decision Support Resolution: A Comparison Between a Generic and Targeted CDS Notification...... 2057 Jessica Ken ; Alina Bogdanov ; Joe Vasey ; Shruti Gangadhar ; Richard Loomis

Challenges Impacting Data Collection from Electronic Health Record (EHR) Systems in Small and Medium Sized Practices in the Midwest ...... 2058 Pauline Kenly ; Luke V. Rasmussen ; Andrew Schriever ; Faraz S. Ahmad ; Kathryn Jackson ; Richard Chagnon ; Theresa L. Walunas ; Abel N. Kho

Leveraging Value Sets from the Value Set Authority Center (VSAC) in a Standards-Based Clinical Data Repository...... 2059 Richard Kiefer ; Luke V. Rasmussen ; Jennifer A. Pacheco ; Peter Speltz ; Joshua C. Denny ; William Thompson ; Jyotishman Pathak ; Guoqian Jiang

Antimicrobial Susceptibility Data Visualization Tool...... 2060 Eugene Y. Kim ; Larry A. Nathanson ; Evan L. Leventhal ; Steven Horng

STDMIG-PGx Implementation in Clinical Trials Using Legacy PGx DB...... 2061 Eun-Young Kim ; Su-Yeon Park ; Na-Yul Kim ; Eun-Young Cha ; Jae-Gook Shin

Guiding Principles for the Duke Connected Care Predictive Modeling Pilot ...... 2062 Eugenie Komives ; Shelley A. Rusincovitch ; John Paat ; Lawrence Carin ; Daniel Costello ; Michael Gao ; Bradley G. Hammill ; Ricardo Henao ; N. B. Neely ; Ursula Rogers ; Devdutta Sangvai ; Mary Schilder ; Erich Huang

Machine Learning Models to Predict Readmission for Patients with Cirrhosis ...... 2063 Jejo D. Koola ; Aize Cao ; Guanhua Chen ; Amy Perkins ; Samuel B. Ho ; Sharon E. Davis ; Michael E. Matheny

Combining Social and Behavioral Determinants of Health Questionnaires to Inform Precision Medicine in a Community Health Center Clinic...... 2064 Taneya Y. Koonce ; Sheila V. Kusnoor ; Suzanne T. Hurley ; Kalonji M. McClellan ; Nunzia B. Giuse

Combined Approach to Lyme Disease Surveillance Using Text Mining and Structured Data Elements Available in Electronic Health Record ...... 2065 Rajesh Koralkar ; Elham Sagheb Hossein Pour ; Jennifer Meece ; Anna Schotthoefer

Evaluation and Adoption of Security Standards to Improve Information Security in Healthcare Administration Systems...... 2066 Gunes Koru ; Prashansa Rao

The Accuracy of Monitoring Stress from Wearable Devices ...... 2067 Maciej Kos ; Christine Gordon ; Xuan Li ; Iman Khaghani-Far ; Misha Pavel ; Holly B. Jimison

An Exploratory Analysis of the Excessive Administration of Seasonal Influenza Vaccinations in Minnesota ...... 2068 Samuel J. Kozloff ; Miriam H. Muscoplat ; Zeke McKinney

Digital Activity Tracker-Based Behavioral Characteristics Associated with Comorbid Mental Health Illness Symptoms Among Individuals With Diabetes...... 2069 Shefali Kumar ; David Stück ; Wei-Nchih Lee ; Jessie Juusola ; Luca Foschini

Mapping U.S. FDA National Drug Codes to Anatomical-Therapeutic-Chemical Classes using RxNorm ...... 2070 Fabricio S. P. Kury ; Olivier Bodenreider

Rapid Low-Cost Usability Engineering: Can We Demonstrate the Cost-Effectiveness of the Method for Ensuring Usability of Health IT?...... 2071 Andre W. Kushniruk ; Elizabeth M. Borycki

Reach and Impact of an EHR Pain Care Clinical Decision Support Program ...... 2072 Steven Labkoff ; Christopher Bond ; Lee Kallenbach ; Nam Nguyen ; Shruti Gangadhar ; Dan O’Brien

Substance Use Extraction in Cancer Patients' Clinical Notes ...... 2073 William A. Lane ; Emily Silgard ; Spencer Morris

New MetaMap Features for Processing Numerical Tables ...... 2074 Francois-Michel Lang ; Dina Demner-Fushman

Leveraging Clinical Decision Support Tools to Improve Early Recognition and Treatment of Pediatric Sepsis ...... 2075 Michael E. Lang ; Anna Keller ; Robert S. Heidersbach, H. Flori

Understanding Ovarian Cancer Symptoms from Patients’ Perspective: A Topic Modeling Approach ...... 2076 Young Ji Lee ; Albert Park ; Heidi Donovan ; Mary Roberge

Meeting Common Health-Related Needs Through a Pediatric Inpatient Engagement Consultation Service ...... 2077 Daniel J. Lee ; Robert M. Cronin ; Kim M. Unertl ; Jamie Robinson ; Katherine Kelly ; Shilo H. Anders ; Jennifer Wilkens ; Gretchen P. Jackson

Predictive Modeling for the Prevention and Surveillance of Adolescent Substance Abuse and its Implications for Nursing...... 2078 Mikyoung Lee ; Dawn M. Murphy ; Suzanne Gillson ; Leolin Castillo ; Anila Simon

Analyzing Patient Data Entry Patterns of Free Text based Family History Disease Concepts...... 2079 Jaehoon Lee ; Nathan C. Hulse ; Stacey Knight

Spanish Text Simplification Using Term Familiarity: Applying Principles from English Text Simplification ...... 2080 Gondy Leroy ; Brianda Armenta Navarrete ; Sonia Colina ; David Kauchak

A Pilot Study on the Coverage of ICD and SNOMED CT of Problem List Terminologies Used in a Large Healthcare Institute in China...... 2081 Yuxi Li ; Jie Jiang ; Yan Zhang ; Jianping Li ; Yong Huo

End-to-End Solution to Improve User Experience of TranSMART: From Data Curation to Advanced Data Analytics ...... 2082 Haiqing Li ; Eric Jiang ; Ajay Shah

Correlation Between End-User Experience and Clinical Effectiveness of a Clinical Decision Support Tool for the Management of Uncontrolled Hypertension ...... 2083 Victor S. Lin ; Andrew Holdaway ; Neris Nieves-Robbins ; Robert C. Marshall ; Keith Solveson ; Robert D. Highley ; Leilani A. Siaki

Integrating Smart Pump Infusion Data with Electronic Health Record Data to Analyze Medication Administration Alerts...... 2084 Todd Lingren ; Yizhao Ni ; Eric S. Hall ; Mattew Leonard ; Eric Kirkendall ; Kristin Melton

Using Machine Learning to Predict Hospital Acquired Sepsis ...... 2085 Xinran Liu ; Greg McKelvey ; James Marquardt ; Rosemary M. Grant ; David Carlbom

Number of Citations of Structured and Unstructured Abstracts in PubMed...... 2086 Fang Liu ; Paul Fontelo

Detection of Weight Data-Entry Errors...... 2087 Jing Liu ; Laura E. Brown ; Judith Dexheimer ; Stephen A. Spooner

Building an Obesity and Cancer Semantic Web Knowledge Base...... 2088 Juan Antonio Lossio-Ventura ; William Hogan ; François Modave ; Amanda Hicks ; Yi Guo ; Zhe He ; Mirela Vasconcelos ; Jiang Bian

Characterization of Information Collected from Decision Support Request Forms in Academic Medical Centers ...... 2089 Jean F. Louis ; Guilherme Del Fiol ; Rachel Richesson

Enhancing LexSynonym Features in the Lexical Tools ...... 2090 Chris J. Lu ; Destinee L. Tormey ; Lynn McCreedy ; Allen C. Browne

Current Practices in Integrating Social and Behavioral Data into Patient Care at a VAMC ...... 2091 Cherie L. Luckhurst ; Michael Weiner

Computer Vision-based Approach to Maintain Independent Living for Seniors...... 2092 Zelun Luo ; Alisha Rege ; Guido Pusiol ; Arnold Milstein ; Fei-Fei Li ; N. Lance Downing

Meaningful Use Stage 3 Safety-Enhanced Design: Third Time’s a Charm? New Certification Criteria, Insights and Lessons Learned ...... 2093 Andrea Mahnke ; Gabrielle Falkey ; Elise Ewers

Repurposing Software Built for Large Clinical Trials for Use in Small Trials...... 2094 Nilla Majahalme ; Stephen Miller ; Andrew J. Zimolzak ; Jason Vassy

Optimizing Parameters of word2vec for a Text Classification Task...... 2095 Vincent Major ; Alisa Surkis ; Yindalon Aphinyanaphongs

Guideline Based Recommended Therapies in PAD Patients Identified by NLP: A Quality Assessment Project...... 2096 Vishnu Priya Mallipeddi ; Naveed Afzal ; Iftikhar J. Kullo ; Hongfang Liu ; Rajeev Chaudhry ; Adelaide Arruda-Olson

Application of Machine Learning Algorithms for Identification of Contaminated Blood Samples: Accuracy and Validity Examination...... 2097 Jason V. Mancuso ; Peter Short ; Edumnds Reineks ; Elena A. Manilich

Implementing Data Event Triggers with Standard-based Document Exchange to Improve Timely Communication for Referring Providers...... 2098 Darren K. Mann ; Shan He ; Jennifer Nelson ; Gary Anderson ; Sidney N. Thornton

Evaluation of the Surveillance, Epidemiology, and End Results Data Management System (SEER*DMS) to Support the Efforts in Enhancing U.S. Cancer Surveillance...... 2099 Marina Z. Matatova ; Paul Fearn ; Eric Durbin ; Gary Levin ; Frank J. Manion ; Patrick Mergler

A Data-driven Framework for Sub-Typing Stem Cell Transplant Recipients at Risk for Infection...... 2100 Anoop Mayampurath ; Jonathan Matthews ; Samuel L. Volchenboum ; Lazaro N. Sanchez-Pinto

HealthPro: An Integrated Web Application for Essential Health Data and Biological Specimen Collection in the Precision Medicine Initiative...... 2101 Kelsey R. Mayo ; Robert J. Carroll ; Jason Tan ; Rebecca Johnston ; Celecia M. Scott ; Joshua C. Denny ; Paul Harris

Electronic Health Record Safety: Identifying Measures for Clinical Decision Support Quality ...... 2102 Allison B. McCoy ; Adam Wright ; Hardeep Singh ; Marie Krousel-Wood ; Dean F. Sittig

Engaging Bedside Nurses in the EHR Change Request Process...... 2103 Jacquel J. McDonald ; Kimberly C. Burress

SMARTenAPP: The Development of a Web-Based Application as an Antimicrobial Stewardship Intervention: A Pilot Project...... 2104 Richard Medford ; Siddhartha Srivastava ; Gerald Evans

Cross-species Mapping of Human and Mouse Craniofacial Structures ...... 2105 Jose Mejino ; Landon T. Detwiler ; Timothy C. Cox ; James F. Brinkley

Use of an iPad Program to Improve Access to Physical Therapy Services for the Management of Chronic Low Back Pain...... 2106 Brittany L. Melton ; Zoe Lai ; Neena Sharma

Research on the Accessibility of Parks Based on GIS in 8 districts of Beijing ...... 2107 Yujie Meng ; Xiaopeng Qi ; Songwang Wang ; Qiang Chen ; Rui Zhang ; Huan Zheng

An NLP Tool for Boosting Annotation Capture from Clinical Documents...... 2108 Frank Meng ; Craig Morioka ; Weixia Yu ; Nilla Majahalme ; Danne C. Elbers ; Sergey Goryachev ; Nhan V. Do

Reflecting on Diabetes Self-Management Logs with Simulated, Continuous Blood Glucose Curves: A Pilot Study ...... 2109 Elliot G. Mitchell ; Matthew Levine ; David Albers ; Lena Mamykina

Clinical Informatics for Precision Cancer Medicine: Computational Methods for Interpreting Individual Whole Exome and Transcriptome Tumor Sequence Data...... 2110 Nathanael D. Moore ; Brendan Reardon ; Eliezer M. Van Allen

A Comparison of Stroke Classifiers Leveraging Hospital Billing Codes Versus Natural Language Processing ...... 2111 Danielle L. Mowery ; Brent D. Hill ; Mingyuan Zhang ; Wendy Chapman ; Lisa Cannon-Albright ; Jennifer Majersik

Developing a Biomedical Information System for the Geo-Spatial Analysis of California Office of Statewide Health Planning and Development (OSHPD) Data Among Minority Population in Los Angeles...... 2112 Sukrit Mukherjee ; Paul L. Robinson

Global HIV Case Surveillance Using Electronic Medical Records (EMR) Data ...... 2113 Lisa A. Murie ; Eric-Jan Manders ; James M. Kariuki ; Mahesh Swaminathan ; Xenophon Santas

Does Practice Follow Guidelines? Improving Accuracy for Comparison of Structured and Unstructured Text in Medical Records to Expectations...... 2114 William J Murphy ; Martin M. Yadrick ; Rosa K. Hand

Vaccine Code Set Management Service Pilot ...... 2115 Stuart Myerburg ; Regina Cox

Pilot Study Using Wearable and Mobile App Data in Patients with the Sickle Cell Disease to Describe and Predict Painful Vaso-Occlusive Crisis ...... 2116 Kalindi Narine ; Fan Yang ; Tanvi Banerjee ; Jude Jonassaint ; Nirmish Shah

The Pulse: An Interactive Web-based Application for Tracking Clinical Quality Measure Performance ...... 2117 Benjamin E. Nealy ; Raja A. Cholan ; Nicholas Colin ; Bhavaya Sachdeva ; Kevin G. Loftis ; David A. Dorr

Experiences Implementing a User-Centered Design Process across a Large Patient Safety Learning Laboratory...... 2118 Pamela M. Neri ; Anuj K. Dalal ; Theresa E. Fuller ; Dominic Breuer ; Awatef Ergai ; David Bates ; James Benneyan

Impact of Predictive Analytics on Clinical Outcomes, Clinical Decision Making, and Healthcare Organization Performance: A Systematic Review...... 2119 Neris M. Nieves-Robbins ; Matthew Parry ; Andrew Holdaway ; Robert C. Marshall ; Fredric Wolf ; Peter Tarczy-Hornoch

Data Management, Sharing, and Citation Strategies in The Cancer Imaging Archive (TCIA) ...... 2120 Tracy Nolan ; Justin S. Kirby ; Fred W. Prior

The Depth of Historical Electronic Information Seeking by ICU Clinicians ...... 2121 Matthew E. Nolan ; Rodrigo Cartin-Ceba ; Pablo Moreno Franco ; Brian W. Pickering ; Vitaly Herasevich

The Relationship Between “Reason for Exam”, Radiologist’ Perceived Unexpected Effort, and the Time to Complete Interpretation ...... 2122 Daniel T. Nystrom ; Heidi Kramer ; Marta E. Heilbrun ; Charlene Weir

Using Point of Care Systems to Deliver Patient-Centric Care: Lessons from an Australian Case Study...... 2123 Louise O'Connor ; Peter Haddad ; Nilmini Wickramasinghe

Validation of the Knowledge and Self-Management NOC Outcomes for Adults with Diabetes...... 2124 Hyunkyoung Oh ; Sue Moorhead

Parsing MetaMap Files in Hadoop...... 2125 Amy L. Olex ; Alberto Cano ; Bridget McInnes

Medication Errors Following a Home-Grown Electronic Health Record Implementation: Identifying and Overcoming Unanticipated Challenges...... 2126 Waldo Ortega ; Carolina Ibañez ; Marcelo A. Lopetegui

Information and Communication Technologies Adoption by Healthcare Professionals in Brazil...... 2127 Cristina Lúcia F. Ortolani ; Fabio Senne ; Alexandre Barbosa ; Heimar Marin

Sepsis Risk Stratification Among the CMS Oncology Care Payment Model Population...... 2128 Benjamin Orwoll ; Konrad Dobbertin ; Michael A. Savin ; David A. Dorr ; Peter Graven

Implementing a Real-Time Location System (RTLS) at an Ambulatory Oncology Surgical Center...... 2129 Aaron Ostrovsky ; Daniel Stein ; Brett Simon ; Justin McManus ; Alexander Stevens ; Marcia Levine ; Peter Stetson

Innovative Approaches in Informatics Education...... 2130 Bunyamin Ozaydin ; Sue Feldman ; Laura J. McNeill ; Amanda Dorsey ; Meg Bruck ; Eta S. Berner

Portable Precision Phenotype Algorithm for Chronic Rhinosinusitis...... 2131 Jennifer A. Pacheco ; Agnes S. Sundaresan ; Kenneth M. Borthwick ; Sergio E. Chiarella ; David T. Coleman ; Andy Y. Wu ; Abel N. Kho ; M Geoffrey Hayes ; Marc S. Williams

Towards Spatial Analysis of Opioid Abuse Using Twitter ...... 2132 Sheetal Mangesh Pandrekar ; Manish Valakonda ; Xin Chen ; Fusheng Wang

Building Better Timeline Interactions for Patient Chart Reviews...... 2133 Heekyong Park ; Taowei D. Wang ; Vivian Gainer ; Victor M. Castro ; Shawn N. Murphy

Identifying Health Interests of the General Public using Reddit ...... 2134 Albert Park ; Mike Conway

Explorative Analyses on Indexing OMOP based Clinical Datasets with DATS ...... 2135 Ethan Park ; Diana Guijarro ; Imho Jang ; Stephen Trac ; Nansu Zong ; Hyeoneui Kim

Lessons Learned from the Conversion of MIMIC3 to the OHDSI Common Data Model...... 2136 Joongheum Park ; Liana Tascau ; Adler Perotte

Assessment of Laboratory System-Assigned LOINC Codes for Common Tests ...... 2137 Sharidan K. Parr ; Shuanghui Luo ; Sina Madani ; S T. Rosenbloom

Validating Vector Representations of ICD Diagnoses Using Readmission Prediction and Dissimilarity Testing: A Pilot Study ...... 2138 Matthew Parry ; Neris Nieves-Robbins ; Keith Solveson ; Eric A. Shry

The Adolescent Patient Portal: Are We Meeting the Needs of Our Most Connected Patients? ...... 2139 Chase R. Parsons ; Jonathan D. Hron ; Fabienne C. Bourgeois

America Walks, a Cross-platform Mobile ResearchKit Study of Walking Behavior Based on Passive Step Tracking ...... 2140 Chintan Patel ; Nickolas Whiting ; Aamir M. Bhat ; Mir Suhail ; Priya Menon ; Shweta Mishra ; Sharib Khan

For the Common Good: Sharing Data Extracted from Text...... 2141 Olga V. Patterson ; Scott L. Duvall

Distance Learning as a Strategy for the Education of Health Informatics Professionals: Possibilities and Challenges...... 2142 Andréa P. S. Pelogi ; Ivan T. Pisa ; Alissa P. Penteado ; Claudia G. Novoa

RxNav 2.0 – A Web-based, Mobile-Responsive RxNorm Browser...... 2143 Lee Peters ; Olivier Bodenreider

Assessing Inter-Hospital Clinical Processes Variability with Process Mining ...... 2144 Marius Petruc ; Mihail Popescu

Developing a Framework for Evaluating Influencers of Frailty in Aging ...... 2145 Andrew B. Phillips ; Margarita Sordo ; Ruth Palan Lopez ; Jacqueline Merrill

A Simple and Efficient Method for Private Exact Matching ...... 2146 Le T. Phong ; Xiaoqian Jiang ; Shuang Wang

A Usability Study to Evaluate the Impact of a Novel Automated Brain Tumor Assessment Application...... 2147 Edgar A. Rios Piedra ; Iren Orosz ; Mary Zide ; Suzie M. El-Saden ; Ricky Taira ; Alex A. Bui ; William Hsu

Presentation of Clinical Pathways for Improved Provider-Patient Shared Decision Making...... 2148 Jose Pineda ; Lina Bouayad ; Min Chen

Data Munging Tricks Can Build Better High Risk Maternity Predictive Models...... 2149 Andrew Placona ; Fengjuan Wang ; Shantanu Phatakwala ; Nick Toure

A Comprehensive Variant Analysis System for Molecular Pathology...... 2150 A. Pozhitkov ; Srinivas Bolisetty ; Fortino Martinez ; Karthik Honnavali ; Tarrah Kirkpatrick ; Milad Guirgus ; Ramesh Rout ; Ajay Shah ; Raju Pillai

Mobile System to Gather Patient-Generated Data in Parkinson’s Disease Treatment...... 2151 Marco Prenassi ; Pierluigi D'Antrassi ; Lorenzo Rossi ; Sergio Barbieri ; Simona Mrakic-Sposta ; Sara R. Marceglia

Promoting Adherence to Antiretroviral Therapy in HIV-infected Patients Using Mobile Phone Text Messaging Technology ...... 2152 Yuri Quintana ; Eduardo Martotell ; Darren Fahy

MeSHgram: An Open Source Tool to Visually Browse Co-occurrence of MeSH Terms in PubMed...... 2153 Satyajeet Raje ; Ravi Teja Bhupatiraju ; Abdelrahman Hosny ; Ben Busby

Reducing Uncoded Allergy Information in the Electronic Health Record ...... 2154 Harley Z. Ramelson

Setting the Stage for Implementing an EHR-Integrated Social Knowledge Networking (SKN) System on Medication Reconciliation: Phase 1 Results ...... 2155 Pavani Rangachari

Use of the popHealth Open-Source Quality Measure Engine to Support Cardiovascular Care at Small- and Medium-Sized Practices...... 2156 Luke V. Rasmussen ; Andrew Schriever ; Pauline Kenly ; Dejan Jovanov ; Stephen D. Persell ; Theresa L. Walunas ; Abel N. Kho

Exploring Barriers to the Use of Electronic Health Records in the Trauma Room Using a Cognitive Work Analysis...... 2157 Ryan J. Rasmussen ; Jane M. Carrington

Evaluation of EHR Tools to Decrease Data Entry Burden for Researchers ...... 2158 Taylor L. Read ; Sarah Collins ; Neelima Karipineni ; Mahesh Shanmugam ; Saverio M. Maviglia ; J Perren Cobb ; Roberto A. Rocha

Examining Nurses’ Use of Electronic Health Records to Document Symptoms in Acute Care Settings ...... 2159 Blaine Reeder ; Mustafa Ozkaynak ; Mary Beth Flynn Makic ; Karen Sousa

Natural Language Data Sampling: Principles & Strategies in Corpus Selection ...... 2160 Ruth M. Reeves ; Nancy H. Gentry ; Fern Fitzhenry ; Glenn T. Gobbel ; Michael E. Matheny

Creating a Corpus Resource for Text Simplification R & D...... 2161 Debra Revere ; Partha Mukherjee ; David Kauchak ; Gondy Leroy

Family Data Linkage Methods Using EHR Data...... 2162 Pedro Rivera ; Megan Hoopes ; Stuart Cowburn ; Jon Puro

Sub-Phenotyping of Crohn’s Disease Using a Large Electronic Record Cohort ...... 2163 Jamie R. Robinson ; Lisa Bastarache ; Robert J. Carroll ; Elizabeth A. Scoville ; David A. Schwartz ; Joshua C. Denny

Critical Factors for Developing a Personalized Warfarin Dosing Protocol: A Scoping Review Analysis...... 2164 Jacee Robison ; Jia-Wen Guo

Towards the Effective Management of EHR Configuration Integrity...... 2165 Roberto Rocha ; Priyaranjan Tokachichu ; Margarita Sordo ; Christopher J. Vitale ; David H. Dubois ; Saverio M. Maviglia

Automated Extraction of Pediatric Obese and Allergic Related Asthma Phenotypes from the Electronic Health Record...... 2166 Mindy K. Ross ; Javier Sanz ; Douglas S. Bell

Can Automated Retrieval of Data from Emergency Department Physician Notes Enhance Radiology Order Entry Process? ...... 2167 Justin F. Rousseau ; Ivan Ip ; Ali S. Raja ; Vlad Valtchinov ; Jeremiah D. Schuur ; Ramin Khorasani

Physician Negation of Nursing Concepts in the Electronic Health Record ...... 2168 Khawllah Roussi ; Karen Dunn Lopez ; Barbara Di Eugenio ; Andrew Boyd

Oncology Precision Network...... 2169 Kerry Rowe ; Lincoln Nadauld

Development of an Automated Annual Cumulative Susceptibility Reporting Process...... 2170 W. Cliff Rutter ; David S. Burgess

MyHealthKeeper: Clinical Trial of Personal Health Record-Based Healthcare Management...... 2171 Borim Ryu ; Nari Kim ; Eunyoung Heo ; Sooyoung Yoo ; Se Young Jung ; Yoojung Kim ; Joongsik Lee ; Jeong-Whun Kim

Innovative Method for Measuring Nursing Workload ...... 2172 Virginia K. Saba ; Luann Whittenburg

Remote Usability Testing Method for an EHR Platform...... 2173 Inkeri Saiku ; Yalini Senathirajah ; Elizabeth M. Borycki ; Andre W. Kushniruk ; Upasana Malik ; Jinglu Wang

Anticoagulation Safety Risk Assessment: Evaluating Compliance with an Anticoagulation Protocol Through Secondary Use of EHR Data...... 2174 Hojjat Salmasian ; Eric Venker ; Emilia Hermann ; Iheanacho O. Emeruwa ; Dnaiel Farrell ; Jason Adelman

Detecting Adverse Drug Event Safety Signals from MEDLINE Reports: Challenges in Employing Cross- terminology Mapping of MeSH to MedDRA ...... 2175 Abhivyakti Sawarkar ; Alfred Sorbello ; Anna Ripple ; Olivier Bodenreider

Development of a Conceptual Model for Clinical Deployment of e-Patient-Reported Outcomes ...... 2176 Courtney Segal ; Cynthia Lerouge ; Liz Kellogg ; Elizabeth Austin ; Danielle C. Lavallee

Evaluating the Appropriateness of Medication Related Clinical Decision Support Alert Overrides in the Inpatient and Outpatient Settings ...... 2177 Diane L. Seger ; Adrian Wong ; Mary G. Amato ; Sarah P. Slight ; Patrick E. Beeler ; Olivia Dalleur ; Tewodros Eguale ; Christine A. Rehr ; Julie M. Fiskio ; Karen C. Nanji ; David Bates

DeepSuggest: Query Expansion for Clinical Notes by Deep Learning...... 2178 Emre Sezgin ; Koushik Jinna ; Tran Bourgeois ; Soheil Moosavinasab ; Yungui Huang ; Simon Lin

Mapping CT Codes from a Health Information Exchange to LOINC...... 2179 Jason S. Shapiro ; Anton O. Beitia ; Tina Lowry ; Daniel J. Vreeman ; Bradley Delman ; George T. Loo ; Frederick L. Thum

Robust Lung Nodule Classification using 2.5D Convolutional Neural Network...... 2180 Shiwen Shen ; Alex A. Bui ; William Hsu

Accelerating Rare Disease Diagnosis with Collaborative Filtering ...... 2181 Feichen Shen ; Sijia Liu ; Yanshan Wang ; Liwei Wang ; Naveed Afzal ; Hongfang Liu

An Approach for Preventive Healthcare for Elderly People in Japan Using an Information and Communication Technology-based System...... 2182 Akiko Shibuya ; Tsuneo Yamada ; Jimpei Misawa ; Yukihiro Maeda ; Rie Ichikawa ; Teruyoshi Hishiki ; Yoshiaki Kondo

Anesthesia Instrument Recognition System ...... 2183 Scott Siegel ; Agyeiwaa O. Agyei ; Anis Davoudi ; Patrick Tighe ; Parisa Rashidi

An Observational Study of Clinical Application Downtimes in an Electronic Health Record...... 2184 Rizwan Siwani ; Mohamed O. Seise; V. Herasevich

Do They Talk About Risk? An Exploratory Study for Developing Tools to Prevent Delirium in Older Hospitalized Patients...... 2185 Stacey Slager ; Teresa Taft ; Daniel T. Nystrom ; Bryan Gibson ; Charlene Weir

Health Care Providers’ Experiences of Moving from a Home-grown EHR System to a Commercial System ...... 2186 Sarah P. Slight ; Diane L. Seger ; Christine A. Rehr ; Sabrina A. Fowler ; Elizabeth R. Silvers ; Adrian Wong ; Mary G. Amato ; Nivethietha Maniam ; Michael Swerdloff ; David Bates

HIPAA and eCR: Are You Sharing the ‘Minimum Necessary’?...... 2187 Crystal Snare ; Julie Simon ; Rita Altamore ; Kim Peifer

Metadata Mapping Challenges in bioCADDIE...... 2188 Shao Ling Soh ; Sze Nga Wong ; Ethan Park ; Diana Guijarro ; Nansu Zong ; Hyeon-Eui Kim

Bayesian Prediction of Asthma Exacerbation in Children ...... 2189 Sunghwan Sohn ; Young J. Juhn ; Sungrim Moon ; Chung-Il Wi ; Katherine S. King ; Euijung Ryu ; Hongfang Liu

Mining Associations between Drug Abuse, Age, and Suicide Attempts...... 2190 Brinda Somasundaram

Exploration of Semantic Expressions to Define Classification Rules ...... 2191 Margarita Sordo ; Benjamin J. Gross ; Priyaranjan Tokachichu ; Christopher J. Vitale ; Saverio M. Maviglia ; Roberto A. Rocha

Multi-Agent System Architecture to Measure Patient Engagement Based on Automatic Patient Authored Text Analysis...... 2192 Fábio Rezende De Souza ; Márcia Ito ; Maira G. De Bayser

The Phenotype Execution and Modeling Architecture: A Roadmap Towards Next-generation Phenotyping Using EHRs ...... 2193 Peter Speltz ; Luke V. Rasmussen ; Richard C. Kiefer ; Jennifer A. Pacheco ; William Thompson ; Guoqian Jiang ; Jyotishman Pathak ; Joshua C. Denny

Essential Components of a Patient Engagement Platform for Comprehensive Cancer Care ...... 2194 Daniel Stein ; Rimma Belenkaya ; Erdeta Bani ; Olga Strachna ; Peter Stetson

Technology Integration Officer: A New Residency Leadership Position...... 2195 Kevin U. Stephens ; Rachelle E. Toman

Content for Visualizations to Enhance HIV-Related Communication Between Patients and Health Care Providers...... 2196 Samantha Stonbraker ; Sheyla Richards ; Mina Halpern ; Suzanne Bakken ; Rebecca Schnall

Selection and On-boarding of Health Information Exchange Partners: The DoD and VA Approach ...... 2197 Norman E. Stone ; Steven Kator ; Roger Price ; Leann Roling ; Crystal Baum ; Kim Heermann-Do ; Margaret Donahue ; Lauren Thompson

Operationalizing Patient Generated Data Collection through Engagement and Iterative Visualization Design...... 2198 Olga Strachna ; Erdeta Bani ; Daniel Stein ; Peter Stetson

Trend Analysis of EHR Events to Facilitate Hypothesis Generation and Data Quality Assessment ...... 2199 Yohan Sumathipala ; Vojtech Huser

Clinical Machine Comprehension Using Case Reports...... 2200 Simon Suster ; Walter Daelemans

Sharing Exome Sequencing Data Between Clinical Sequencing Labs and Healthcare Providers...... 2201 Rajeswari Swaminathan ; Yungui Huang ; Katherine Lintner ; Matthew Pastore ; Sayaka Hashimoto ; Theodora Jacobson ; Danielle Mouhlas ; Simon Lin

Identifying Disease Hierarchical Relation with Concept Embeddings and Distant Supervision ...... 2202 Lingyi Tang ; Yaoyun Zhang ; Hua Xu

A Practical Scientific Workflow of Sharing Large Selected Dataset from Clinical Research Data Repository...... 2203 Shiqiang Tao ; Steve Roggenkamp ; Guo-Qiang Zhang

Developing a Framework for a Comprehensive Data Sharing Program ...... 2204 Asba Tasneem ; Karen Chiswell ; Brian J. McCourt ; Matt Gross ; Eric Peterson ; Michael Pencina

An Evaluation of Syntactic Dependency Parsers on Clinical Data...... 2205 Stuart Taylor ; Travis R. Goodwin ; Sanda M. Harabagiu

Overcoming Policy and Operational Challenges for Health Data Exchange Using a Validation Service for Patient to Provider Relationships ...... 2206 Sidney N. Thornton ; Shan He ; Darren K. Mann ; Iona M. Thraen ; Matt S. Hoffman ; Wu Xu

Assessing Data Quality within Health Information Exchanges: A Case Study for Supporting Emergency Department Research...... 2207 Margaret M. Thorsen ; Indra N. Sarkar ; Elizabeth S. Chen ; Elaine Fontaine ; Gregory Walker ; Megan L. Ranney

Customization of a Commercial CPOE System to Improve Patient Safety...... 2208 Clare L. Tolley ; Neil Watson ; Andrew Heed ; Andrew K. Husband ; David Bates ; Sarah P. Slight

A Random Forest Model for Detecting Somatic Mutations from Unpaired Cancer Samples...... 2209 Sophie Tu ; Bin Zhou ; Da Wei Huang ; Roland Schmitz ; George Wright ; Louis Staudt ; Calvin A. Johnson

A Decision Support Tool to Help Providers Address Perinatal Depression ...... 2210 Bengisu Tulu ; Nicolas Adami-Sampson ; Trivani J. Shahi ; Nicholas Shannon ; Leif A. Waugh ; Drew C. Wethern ; Nancy Byatt ; Tiffany A. Moore Simas ; Kathleen Biebel

Creating RDF Data on Trauma Care Organizations from Questionnaires...... 2211 Joseph R. Utecht ; Jonathan P. Bona ; Mathias Brochhausen

Systematic Evaluation of Smartphone Applications on Spinal Cord Injury Self-Management ...... 2212 Gary Vargas ; Spyros Kitsiou ; Ben S. Gerber

Representation and Validation of Reference Content Sources Within a Commercially Available Knowledge Management System ...... 2213 Christopher Vitale ; Priyaranjan Tokachichu ; Daniel Kim ; Margarita Sordo ; Saverio M. Maviglia ; Roberto A. Rocha

Toward Integrated Memory Assessment in Primary Care ...... 2214 Lisa M. Vizer ; Daniel I. Kaufer

A Diabetes Management Platform to Reduce Severe Hypoglycemia in Older Adults with Type 1 Diabetes...... 2115 Jonathan S. Wald ; Elana Toschi ; Garry M. Steil ; Howard Wolpert ; Christine Slyne ; Tara Macneil ; Astrid Atakov-Castillo ; Stephanie Edwards ; Jennifer R. Webb ; Alexa Ortiz ; Maria Alva ; Robert D. Furberg ; Medha Munshi

Novel Pedigree Analysis Allows for Genetic Heterogeneity to Aid in Gene Discovery for Common, Complex Diseases ...... 2216 Rosalie G. Waller ; Todd M. Darlington ; Myke Madsen ; Robert Klein ; Steven Lipkin ; Celine Vachon ; Nicola Camp

Visual Exploration of Metabolic Networks to Provide Context for Metabolic Profiling in Precision Medicine...... 2217 T. Cameron Waller ; Jared Rutter ; Alexander Lex

Matching Consumer Health Vocabulary with Professional Medical Terms Through Concept Embedding ...... 2218 Yue Wang ; Jian Tang ; V. G. Vinod Vydiswaran ; Kai Zheng ; Hua Xu ; Qiaozhu Mei

Utility of Anti-hypertension Prescription Orders in Predicting Future Hypertensive Instability Events ...... 2219 Xuan Wang ; Lujie Chen ; Marilyn Hravnak ; Gilles Clermont ; Michael R. Pinsky ; Artur Dubrawski

Semantic Representations of Medical Terms: A Comparison Study of Word Embeddings Trained on Clinical Notes and PubMed Articles...... 2220 Yanshan Wang ; Naveed Afzal ; Liwei Wang ; Feichen Shen ; Hongfang Liu

Neural Network Word Embeddings for Text Classification of MeSH terms...... 2221 Walter Wang ; Yindalon Aphinyanaphongs

Come Together: A Multi-hospital Transition in Reporting Strategy from Untethered Databases to Integrated Warehouse Solutions...... 2222 Emily C. Webber ; Phillip Cadle ; Cara Willey ; Michael Schwarz ; Rebecca Rose

Resident Physician Efficiency in the Electronic Medical Record (EMR): Sustaining Improvements...... 2223 Emily C. Webber ; Ellen Klink ; Andrew O'Brien ; Courtney Hines

Measures of Improvement: Combining Satisfaction Survey and Time Measures to Identify Impactful Optimization...... 2224 Emily C. Webber ; Wanita Kumar ; Jeff Aldrich ; Cara Willey ; Erika Green ; Zachary N. Gordon ; Matthias Kochmann ; Dan Seitz ; Jason Schaffer

Using Statistical Models to Predict Senior Patients’ Use of Smartphone Apps for Managing Parkinson’s Disease – A Preliminary Study from A Service Learning Project...... 2225 Duo Wei

Using a Convolutional Neural Network for Automatic Medical Subject Headings (MeSH) Assignment...... 2226 Wei Wei ; Zhanglong Ji ; Lucila Ohno-Machado

Computing Performance Analysis on Clinical Document-level Classification...... 2227 Wei-Hung Weng ; Kavishwar B. Wagholikar ; Henry Chueh

Developing an Evaluation Plan for Nationwide Data Infrastructure Programs...... 2228 S. West ; Jacqueline Amoozegar ; Mahima Ashok ; Joshua E. Richardson ; Barry H. Blumenfeld ; Susan Lumsden ; Catherine Cravens

Project A-G-T-C: Adding Genetic Test Data in Clinical Data Warehouse ...... 2229 Jonathan Wickes ; Hyeoneui Kim ; Hyun-Dae Kim ; Jihoon Kim ; Wenhong Zhu ; Lucila Ohno-Machado ; Olivier Harismendy

Secure Text Messaging System to Improve Workflow Efficiency and Provider Satisfaction in Administration of Radiation Therapy...... 2230 Aaron Wild ; Erik Anderson ; Natalie A. Lockney ; Suchit Patel ; Robert Samstein ; Amy Xu ; Keri Martin ; Aaron Ostrovsky ; Chhavi Kumar ; Daniel Stein

Data Cleaning for Peace Corps’ Population Health Surveillance...... 2231 Thomas M. Wilkinson ; Rennie Ferguson ; Daniel Murphy ; Adrianna Evans ; Susan Henderson

Exploration of Contextual Digital Data as a Source of Patient Safety Insight ...... 2232 Dana M. Womack ; Michelle R. Hribar ; Paul Gorman

Factors Affecting the Decision of Heart Failure Patients to Accept Telehealth Services in the Home: An Integrative Review...... 2233 Kyungmi Woo ; Dawn Dowding

A Phenome-Wide Association Study (PheWAS) of Iron Deficiency in a Large Electronic Health Record Database ...... 2234 Patrick Wu ; Joshua C. Denny ; Wei-Qi Wei

Toward Reading Comprehension of Online Health Information: An Initial Annotation ...... 2235 Danny T. Y. Wu ; Seung-Hyun B. Ko ; Chirs A. Feak

Classification Method of Dental Electronic Health Record Data Potentially Improves Precision Treatment ...... 2236 Di Wu

Detecting Contradictory and Consistent Citations in Biomedical Literature ...... 2237 Jun Xu ; Yonghui Wu ; Yaoyun Zhang ; Qiang Wei ; Hua Xu

Evaluation of Automated Spectrographic Seizure Detection Using Scale Invariant Feature Transform and Support Vector Machines ...... 2238 Peter Yan ; Fei Wang ; Ramin Zabih ; Zachary M. Grinspan

Preliminary Study of the Portability of an Automated Text Categorization Model to Identify Unsuspected Lung Nodule Findings in Radiology Reports ...... 2239 Jianji Yang ; Theodore B. Wright ; James Morrison

Visualizing Social Support Mechanisms in English and Spanish Tweets to Meet Self-Management Needs of Family Dementia Caregivers...... 2240 Sunmoo Yoon ; Niurka M. Suero-Tejeda ; Robert J. Lucero ; Suzanne Bakken

Novel Visualization of Clostridium Difficile Infection in Intensive Care Units...... 2241 Sean C. Yu ; Courtney L. Hebert ; Albert M. Lai ; Justin Smyer ; Jennifer Flaherty ; Julie Mangino ; Susan Moffatt-Bruce

Subtype Discovery for Autism Spectrum Disorder by Comorbidity Analysis ...... 2242 Kun-Hsing Yu ; Nathan P. Palmer ; Isaac Kohane

Utilizing EHR-based Recruitment Methods...... 2243 Marianne Zachariah ; Carina V. Hampp ; Ruby Wan ; Amanda L. Do ; Douglas S. Bell

Recommending Education Materials for Diabetic Questions Using Information Retrieval Approaches...... 2244 Yuqun Zeng ; Yanshan Wang ; Feichen Shen ; Sijia Liu ; Liwei Wang ; Majid Rastegar-Mojarad ; Xusheng Liu ; Hongfang Liu

Towards Improving the Quality of Medicaid Data: Identifying Data Defects in a Large Healthcare Administration System ...... 2245 Yili Zhang ; Pratik Tamakuwala ; Gunes Koru

A Twitter Study of the Relationship between the Geographic Variations of HPV Vaccination Rates and Online Information in the United States...... 2246 Hansi Zhang ; Yunpeng Zhao ; Christopher Wheldon ; Xinsong Du ; Terrell Brown ; Yi Guo ; Stephanie Staras ; Jingcheng Du ; Cui Tao ; Jiang Bian

Effects of Clinical Decision Support Implementation on Clinical Guideline Compliance ...... 2247 Yongkang Zhang ; Mark Diana ; Allison B. McCoy

Evaluating Word Embeddings from Multiple Domains for Symptom Recognition in Psychiatric Notes ...... 2248 Yaoyun Zhang ; Hee-Jin Lee ; Yonghui Wu ; Hua Xu

Detecting Off-label Uses of Prescription Drugs with Meta-Path-Based Mining ...... 2249 Mengnan Zhao ; Christopher Yang

HyDeXT: A Hybrid De-identification and Extraction Tool for Health Text...... 2250 Xinyan Zhao ; V. G. Vinod Vydiswaran

The Use of NLP to Identify Tdap Related Local Reaction at Five Health Care Systems in the Vaccine Safety Datalink ...... 2251 Chengyi Zheng ; Wei Yu ; Fagen Xie ; Wansu Chen ; Cheryl Mercado ; Lina Sy ; Lei Qian ; Sungching Gleen ; Hung Fu Tseng ; Jonathan Duffy ; Lisa Lisa A Jackson ; Matthew Daley ; Brad Crane ; Huong McLean ; Steven Jacobsen

Heart on FHIR: Integrating Patient Generated Data into Clinical Care to Reduce 30 Day Heart Failure Readmissions...... 2252 Timothy Bergquist ; Ronald W. Buie ; Kevin Li ; Pascal Brandt

Voice Enabled Framework to Support Post-Surgical Discharge Monitoring ...... 2257 Kevin Blansit ; Rebecca A. Marmor ; Beiqun Zhao ; Dan Tien

Home Behavior Monitoring Module in OpenEMR: Use of Home Sensors As Patient-Generated Data (PGD) for Elderly Care...... 2262 Regina A. Casanova-Perez ; Catharine I. De Freitas-Vidal ; Pierre G. Padilla-Huamantinco ; Yong Kyung Choi

Stand and Move at Work...... 2267 Gabrielle Choonoo ; Mitzi Boardman

Visualizing the Patient-Reported Outcomes Measurement Information System (PROMIS) Measures for Clinicians and Patients...... 2272 Lisa V. Grossman ; Elliot G. Mitchell

Sensi-steps: Using Patient-Generated Data to Prevent Post-stroke Falls ...... 2277 Angela Smith ; Ada Ng ; Eleanor R. Burgess ; Jennifer A. Pacheco ; Noah D. Weingarten

Quantifying and Visualizing Medication Adherence in Patients Following Acute Myocardial Infarction...... 2282 Jane Wang ; Shannon Wongvibulsin ; Katharine Henry ; Saki Fujita

The BD2K Training Coordinating Center’s Data Science Education Platform ...... 2287 Jose-Luis Ambite ; Lily T. Fierro ; Florian Geigl ; Jonathan Gordon ; Gully A. Burns ; Kristina Lerman ; Jeana Kamdar ; Crystal Stewart ; Avnish Bhattrai ; Xiaoyu Lei ; Sumiko Abe ; John D. Van Horn

Systems Demonstration: NIH Common Data Elements Repository...... 2288 Liz Amos ; Christophe Ludet ; Lisa Lang ; Vojtech Huser

CKMS – An Integrated System for Managing Institutional Clinical Knowledge Assets...... 2289 Dominik Aronsky ; Dirk Wenke ; Priyaranjan Tokachichu ; Christopher J. Vitale ; Margarita Sordo ; Saverio M. Maviglia ; Roberto A. Rocha

Vicinity Exploration: Enabling User-Driven Visual Search of Multiple Machine Learning Models for Precision Medicine ...... 2290 Suresh K. Bhavnani ; Archana Ayyaswami ; Tianlong Chen ; Shyam Visweswaran ; Gowtham Bellala ; Kevin Bassler

RxMix – Use of NLM Drug APIs by Non-programmers ...... 2291 Olivier Bodenreider ; Lee Peters

NLM3D: an Open-Source Library of Medical-Imaging-derived 3D Polygonal Models for Use in Public Health, Medical and STEM Applications...... 2292 Kristen Browne ; Anne Altemus

Person-Centric vs. Problem-Centric: Data-driven Heuristics for using Machine Learning to Improve Health Outcomes ...... 2293 John B. Coles ; Brett Cropp ; Michael Moskal ; Jacob Fijas ; Jacob Ekstrum

Improving the Care of Women Through Health Information Technology ...... 2294 Caitlin M. Cusack

AMICUS: A Metasystem for Interoperation and Combination of UIMA Systems...... 2295 Gregory P. Finley ; Benjamin C. Knoll ; Reed McEwan ; Genevieve B. Melton ; Hongfang Liu ; Hua Xu ; Serguei V. Pakhomov mCerebrum and Cerebral Cortex: A Real-time Collection, Analytic, and Intervention Platform for High- frequency Mobile Sensor Data ...... 2296 Timothy Hnat ; Syed Hossain ; Nasir Ali ; Simona Carini ; Tyson Condie ; Ida Sim ; Mani Srivastava ; Santosh Kumar

Enterprise Level Data Restructuring in the Military Health System – Building the Foundation for Optimization and Advanced Analytic Capability...... 2297 Andrew J. Holdaway ; Chris Nichols ; Eric A. Shry

SMART on FHIR Apps from the University of Utah Interoperable Apps and Services (IAPPS) Initiative: Extending the EHR to Optimize Patient Care ...... 2298 Kensaku Kawamoto ; Benjamin S. Brooke ; Guilherme Del Fiol ; Charlene Weir

Web-Service-Enabled Apps for Research: SMART-on-FHIR for OMOP and PCORNet...... 2299 Jeffrey G. Klann ; Kavishwar Wagholikar ; Lori C. Phillips ; Matthew A. Joss ; Shawn N. Murphy

CDS Connect: A New National Repository for Clinical Decision Support Knowledge Artifacts ...... 2300 Edwin Lomotan ; Robert McCready ; Steven Bernstein

Canary: An Information Extraction Platform for Clinical Researchers ...... 2301 Shervin Malmasi ; Nicolae L. Sandor ; Naoshi Hosomura ; Matt Goldberg ; Stephen Skentzos ; Alexander Turchin

Sync for Science (S4S): Helping Patients Share EHR Data with Research ...... 2302 Joshua C. Mandel ; David A. Kreda

Genome Dashboard: An Interactive Tool for the Exploration of Human Genomic Variants and Phenotypic Associations ...... 2303 Katherine Miller ; Rajeswari Swaminathan ; Soheil Moosavinasasb ; Robert Strouse ; Matthew Bailey ; Yungui Huang ; Simon Lin

Systems Demonstration: Fall Prevention and Fire Departments...... 2304 Andrew Muth ; Christopher Hollweg ; Pamela Garcia-Filion ; Michael Smith ; Hamed Abbaszadegan

Applications of the Ontology Abstraction Framework ...... 2305 Christopher Ochs ; James Geller ; Yehsoshua Perl

A Scalable Approach to Federating Distributed Data: The Avec® Platform ...... 2306 Philip R. O. Payne ; Mark Vance ; Peter J. Embi

The All of Us Research Program Researcher Portal: Innovative Access to Unprecendented Data ...... 2307 Andrea H. Ramirez ; Anthony Philippakis ; Goncalo Abecasis ; Paul Harris ; Joshua C. Denny

DocUBuild: A Collaborative System to Enhance Dissemination and Discovery of Genomic Clinical Content ...... 2308 Luke V. Rasmussen ; Casey L. Overby

Creating a Cluster of Preclinical Lessons Using Pharmacogenomic-Focused Patient Case Presentations...... 2309 Blaine Takesue ; Maureen Harrington ; Bradley Allen ; Debra Litzelman ; Paul Dexter

CLAMP – A User-Centric Clinical Natural Language Processing Toolkit ...... 2310 Hua Xu ; Ergin Soysal ; Jingqi Wang ; Min Jiang ; Yonghui Wu

Author Index