NIH Medlineplus Magazine Summer 2020
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Systemic Lupus Erythematosus: Medlineplus Medical Encyclopedia 13/8/19 21:00
Systemic lupus erythematosus: MedlinePlus Medical Encyclopedia 13/8/19 21:00 National Institutes of Health / U.S. National Library of Medicine Home → Medical Encyclopedia → Systemic lupus erythematosus URL of this page: //medlineplus.gov/ency/article/000435.htm Systemic lupus erythematosus Systemic lupus erythematosus (SLE) is an autoimmune disease. In this disease, the immune system of the body mistakenly attacks healthy tissue. It can afect the skin, joints, kidneys, brain, and other organs. Causes The cause of SLE is not clearly known. It may be linked to the following factors: Genetic Environmental Hormonal Certain medicines SLE is more common in women than men. It may occur at any age. However, it appears most often in people between the ages of 15 and 44. The disease afects African Americans and Asians more than people from other races. Symptoms Symptoms vary from person to person, and may come and go. Everyone with SLE has joint pain and swelling at some time. Some develop arthritis. SLE often afects the joints of the fingers, hands, wrists, and knees. Other common symptoms include: Chest pain when taking a deep breath. Fatigue. Fever with no other cause. General discomfort, uneasiness, or ill feeling (malaise). https://medlineplus.gov/ency/article/000435.htm Página 1 de 7 Systemic lupus erythematosus: MedlinePlus Medical Encyclopedia 13/8/19 21:00 Hair loss. Weight loss. Mouth sores. Sensitivity to sunlight. Skin rash: A "butterfly" rash develops in about half the people with SLE. The rash is mostly seen over the cheeks and bridge of the nose. It can be widespread. It gets worse in sunlight. -
Medlineplus Connect?
What is MedlinePlus Connect? What is MedlinePlus Connect? MedlinePlus Connect links health IT systems, patient portals and electronic health record (EHR) systems to relevant, authoritative health information (patient education) from MedlinePlus.gov. The National Library of Medicine, part of the National Institutes of Health, U.S. Department of Health and Human Services, provides this free service. MedlinePlus Connect is a Web application and a Web service that supports the HL7 Context-Aware Knowledge Retrieval (Infobutton) Knowledge Request Standard. What is MedlinePlus? How do patients or providers benefit from MedlinePlus? MedlinePlus.gov offers free, reliable, up-to-date health information in English and Spanish, with no advertisements. Content is from reputable providers, including the National Institutes of Health, and other government and professional organizations. MedlinePlus helps millions of visitors a year access: • Information on over 1,000 diseases, conditions and wellness topics • Videos and other multimedia • An illustrated medical encyclopedia • Medication and supplement information • Links to health information in over 60 languages • and much more… MedlinePlus.gov is your trusted source for health information. MedlinePlus Connect is a service bringing this reputable health information to patients, families, and health care providers when they need it via their patient portal or EHR. How does MedlinePlus Connect work? MedlinePlus Connect responds to requests based on diagnosis (problem) codes, medication codes, and laboratory -
Carrie Ann Inaba Talks About Her Passion for Movement
6 ways you can prevent heart disease! See page 8 WOMEN’S WINTER 2009 healthTODAY MANGIA! Diet pills EASY, LIGHT ITALIAN FARE ARE THEY RIGHT FOR YOU? Colonoscopy Carrie counsel ALL YOU NEED TO KNOW Ann Inaba on her love of dance The Christ Hospital NON-PROFIT ORG US POSTAGE 2139 Auburn Avenue PAID Cincinnati OH 45219 CINCINNATI OH PERMIT #5489 in this issue . 2 LETTER FROM THE FOUNDER Don’t ignore this important exam 3 Keys to healthy blood vessels How three nutrients keep your blood moving 4 Seniors’ quick quiz Test your health savvy 5 Breast cancer: Your surgical options 6 HEALTH HEADLINES What’s making news in women’s health 8 Take it to heart 6 ways you can prevent heart disease 9 SEX & GENDER MATTERS 10 Psoriasis sense 10 Dancing through life Carrie Ann Inaba talks about her passion for movement 13 H E A L T H Y mind Keeping your cool Keys to anger management 14 H E A L T H Y B I T E S Mamma mia! Italian meals go light and healthy 16 Painful periods 14 Don’t let them cramp your style 19 Miracle diet pills? Fat chance! 20 Countdown to colonoscopy What to expect from this lifesaving test 22 HEALTHY MOVES Strike a pose Get fit, flexible and stress-free with yoga 24 H E A L T H smarts How sharp is your vision knowledge? 19 WOMEN’S LETTER FROM THE FOUNDER healthTODAY TH E M A G A Z I N E O F TH E F O U N D A T I O N F O R F E M A L E H ea L T H A W A R E N E S S FOUNDERS Don’t ignore this important exam Mickey M. -
Omenn Syndrome
Omenn syndrome Description Omenn syndrome is an inherited disorder of the immune system (immunodeficiency). Omenn syndrome is one of several forms of severe combined immunodeficiency (SCID), a group of disorders that cause individuals to have virtually no immune protection from bacteria, viruses, and fungi. Individuals with SCID are prone to repeated and persistent infections that can be very serious or life-threatening. Infants with Omenn syndrome typically experience pneumonia and chronic diarrhea. Often the organisms that cause infection in people with this disorder are described as opportunistic because they ordinarily do not cause illness in healthy people. In addition to immunodeficiency, children with Omenn syndrome develop autoimmunity, in which the immune system attacks the body's own tissues and organs. This abnormal immune reaction can cause very red skin (erythroderma), hair loss (alopecia), and an enlarged liver and spleen (hepatosplenomegaly). In addition, affected individuals have enlargement of tissues that produce infection-fighting white blood cells called lymphocytes. These include the thymus, which is a gland located behind the breastbone, and lymph nodes, which are found throughout the body. If not treated in a way that restores immune function, children with Omenn syndrome usually survive only until age 1 or 2. Frequency Overall, the various forms of SCID are estimated to affect 1 in 75,000 to 100,000 newborns. The exact prevalence of Omenn syndrome is unknown. Causes Mutations in several genes involved in immune system function can cause Omenn syndrome. The two most frequent causes are mutations in the RAG1 and RAG2 genes. These genes provide instructions for making proteins that are active in two types of lymphocytes called B cells and T cells. -
Dancing with the Stars Judge Steps up for Animals
CARRIE ANN INABA Genesis 2012 Dancing with the Stars judge steps up for animals Carrie Ann Inaba was working as a Fly Girl on In Living Color in the early 1990s when a stray cat walked through the door to her Los Angeles home and decided he was there to stay. Inaba didn’t know it at the time, but the long-haired black and white kitty she named Shadow would influence the course of her life. “I think that he was absolutely my soul mate. I’ve never had a connection even with another human being as much as I’ve had with this cat. Some people might say that’s crazy, but any- body who’s had it knows exactly what I’m talking about.” Over the years, as her career began to take off, Inaba sensed her calling was to help animals, but she wasn’t sure what her role would be. So she volunteered with local rescue groups. She attended The HSUS’s Gen- amazing healing power. I want to share that esis Awards and learned about a variety of animal protection issues. She stopped eating with people. poultry and red meat. A few years later, she returned to host the Genesis Awards gala. Shadow’s death in 2011 prompted the Dancing with the Stars judge to “really assess What is it about cats in particular that what I’m going to do in this world.” She adopted a 10-year-old boxer with a heart condi- tugs at your heartstrings? tion, a Chihuahua-basenji mix, and two more cats. -
News Release
NEWS RELEASE NOMINEES ANNOUNCED FOR THE 47TH ANNUAL DAYTIME EMMY® AWARDS 2-Hour CBS Special Airs Friday, June 26 at 8p ET / PT NEW YORK (May 21, 2020) — The National Academy of Television Arts & Sciences (NATAS) today announced the nominees for the 47th Annual Daytime Emmy® Awards, which will be presented in a two-hour special on Friday, June 26 (8:00-10:00 PM, ET/PT) on the CBS Television Network. The full list of nominees is available at https://theemmys.tv/daytime. “Now more than ever, daytime television provides a source of comfort and continuity made possible by these nominees’ dedicated efforts and sense of community,” said Adam Sharp, President & CEO of NATAS. “Their commitment to excellence and demonstrated love for their audience never cease to brighten our days, and we are delighted to join with CBS in celebrating their talents.” “As a leader in Daytime, we are thrilled to welcome back the Daytime Emmy Awards,” said Jack Sussman, Executive Vice President, Specials, Music and Live Events for CBS. “Daytime television has been keeping viewers engaged and entertained for many years, so it is with great pride that we look forward to celebrating the best of the genre here on CBS.” The Daytime Emmy® Awards have recognized outstanding achievement in daytime television programming since 1974. The awards are presented to individuals and programs broadcast between 2:00 am and 6:00 pm, as well as certain categories of digital and syndicated programming of similar content. This year’s awards honor content from more than 2,700 submissions that originally premiered in calendar-year 2019. -
Pubmed, Pubmed Central, Medlineplus: What’S the Difference?
PubMed, PubMed Central, MedlinePlus: What’s the Difference? Lea Leininger Health Sciences Librarian UNC Greensboro 12/9/2011 Outline 1. Comparison: PubMed, PubMed Central, MedlinePlus 2. PubMed Overview 3. PubMed Searching 4. MedlinePlus Overview 5. MedlinePlus Searching 6. Additional Resources and Help Comparison PubMed PubMed Central MedlinePlus • Index/db for • Repository of free full • Consumer health medical & related text articles from web portal literature peer reviewed medical & life science • Original content + • > 20 million journals links to librarian- citations: Medline • Cover-to-cover reviewed sites database and more content of back issues of some journals; • Written at 8th • Scholarly & trade other journals only grade reading level journals, a few pop provide selected • Good for general articles • Good for high level public + students audiences (upper • I only visit this site when following links needing basic info level undergrads from PubMed and above) searches These are all free sites from NCBI, the National Library of Medicine, and the NIH PubMed Overview http://pubmed.gov PubMed (1946-present) = Medline + OLDMEDLINE + citations from publishers1 Medline (largest part of PubMed) is also available by subscription from commercial vendors • 5,400 current biomedical and health journals2 • Medicine, nursing, dentistry, veterinary medicine, health care systems, some life sciences • MeSH (Medical Subject Headings) indexing • Useful search limits but no peer reviewed limit • Links to free full text and article purchases 1. PubMed Fact Sheet: http://www.nlm.nih.gov/pubs/factsheets/pubmed.html 2. Medline Fact Sheet: http://www.nlm.nih.gov/pubs/factsheets/medline.html PubMed Searching Typically give a huge pile of results. Keyword searching launches Automatic Term Mapping (ATM) to MeSH terms; if no match found, then to journal names, then author names1 Easy starting keyword searches • Follow Limits link then enter your keywords in the search box at the top • Or Clinical Query at PubMed home (for patient treatment questions) = your keywords. -
F9 Gene Coagulation Factor IX
F9 gene coagulation factor IX Normal Function The F9 gene provides instructions for making a protein called coagulation factor IX. Coagulation factors are a group of related proteins that are essential for the formation of blood clots. After an injury, clots protect the body by sealing off damaged blood vessels and preventing further blood loss. Coagulation factor IX is made in the liver. This protein circulates in the bloodstream in an inactive form until an injury that damages blood vessels occurs. In response to injury, coagulation factor IX is activated by another coagulation factor called factor XIa. The active protein (sometimes written as coagulation factor IXa) interacts with coagulation factor VIII and other molecules. These interactions set off a chain of additional chemical reactions that form a blood clot. Health Conditions Related to Genetic Changes Hemophilia Mutations in the F9 gene cause a type of hemophilia called hemophilia B. More than 900 alterations in this gene have been identified. The most common mutations change single DNA building blocks (base pairs) in the gene. A small percentage of mutations delete or insert multiple base pairs or rearrange segments of DNA within the gene. Mutations in the F9 gene lead to the production of an abnormal version of coagulation factor IX or reduce the amount of this protein. The altered or missing protein cannot participate effectively in the blood clotting process. As a result, blood clots cannot form properly in response to injury. These problems with blood clotting lead to excessive bleeding that can be difficult to control. Mutations that completely eliminate the activity of coagulation factor IX result in severe hemophilia. -
Medlineplus for Health Professionals
Educate Patients and Families External Resources MedlinePlus offers a wide variety of resources to • Links to selected websites vetted through educate patients and their families on their disease the National Institutes of Health (NIH) or condition: including other government agencies, ® • Handouts – over 30,000 links to professional organizations and partners MedlinePlus informational and printable web pages, and • Links to resources include genetic testing for Health Professionals downloadable items in English with over and related sites, health literacy 10,000 links to Spanish materials information and health statistics from the at: http://medlineplus.gov/ National Center for Health Statistics • The Multiple Languages link points to Information for Patients & Families information in nearly 50 languages Linking to MedlinePlus and Resources for Health Professionals • Easy-to-Read materials use common words http://www.nlm.nih.gov/medlineplus/linking.html for diseases and conditions • Patient education information including Anyone is welcome to link to MedlinePlus handouts and easy-to-read resources • The A.D.A.M. Medical Encyclopedia in and/or to any of its health topic pages. English and Spanish is updated quarterly • Links to authoritative information in multiple languages • Over 950 Health Topics on disorders, MedlinePlus Connect links information to diagnosis, etc., are reviewed twice a year patient portals and electronic health records; • Easy to understand patient instruction with new links added daily see: http://medlineplus.gov/connect. pages in the Medical Encyclopedia • Interactive Tutorials and Anatomy Videos • Links to searches of PubMed/MEDLINE Need Help? in English and Spanish, plus hour-long for patient appropriate journal articles Surgery Videos updated annually Librarians find health information for patients • Extensive library of anatomy and surgery and professionals. -
Severe Congenital Neutropenia
Severe congenital neutropenia Description Severe congenital neutropenia is a condition that causes affected individuals to be prone to recurrent infections. People with this condition have a shortage (deficiency) of neutrophils, a type of white blood cell that plays a role in inflammation and in fighting infection. The deficiency of neutrophils, called neutropenia, is apparent at birth or soon afterward. It leads to recurrent infections beginning in infancy, including infections of the sinuses, lungs, and liver. Affected individuals can also develop fevers and inflammation of the gums (gingivitis) and skin. Approximately 40 percent of affected people have decreased bone density (osteopenia) and may develop osteoporosis, a condition that makes bones progressively more brittle and prone to fracture. In people with severe congenital neutropenia, these bone disorders can begin at any time from infancy through adulthood. Approximately 20 percent of people with severe congenital neutropenia develop certain cancerous conditions of the blood, particularly myelodysplastic syndrome or leukemia during adolescence. Some people with severe congenital neutropenia have additional health problems such as seizures, developmental delay, or heart and genital abnormalities. Frequency The incidence of severe congenital neutropenia is estimated to be 1 in 200,000 individuals. Causes Severe congenital neutropenia can result from mutations in one of many different genes. These genes play a role in the maturation and function of neutrophils, which are cells produced by the bone marrow. Neutrophils secrete immune molecules and ingest and break down foreign invaders. Gene mutations that cause severe congenital neutropenia lead to the production of neutrophils that die off quickly or do not function properly. -
UCLA WOMEN’S TENNIS 2013 Team Photo / Roster Info
2013 UCLA WOMEN’S TENNIS 2013 Team Photo / Roster Info. 2013 Bruins — Front Row (L-R): Head Coach Stella Sampras Webster, Kyle McPhillips, Dylan Kirsch, Robin Anderson, Chanelle Van Nguyen, Kaitlin Ray, Catherine Harrison, Volunteer Assistant Coach Laura Gordon, Associate Head Coach Rance Brown. Back Row (L-R): Megan Lester, Skylar Morton, Courtney Dolehide, Holly Fleming, Morgan Thomas, Pamela Montez. 2013 Roster Team Personnel Head Coach: Stella Sampras Webster Name Ht. Yr. R/L Hometown (Previous School) 17th Season, UCLA ‘91 Robin Anderson 5-3 So. R Matawan, NJ (Matawan Regional) Courtney Dolehide 6-0 Jr. R Hinsdale, IL (Hinsdale Central) Associate Head Coach: Rance Brown Holly Fleming 5-11 RSr. L London, England (Latymer Upper School) 16th Season, Long Beach State ‘11 Catherine Harrison 5-5 Fr. R Germantown, TN (Laurel Springs) Volunteer Assistant Coach: Laura Gordon Dylan Kirsch 5-5 Fr. R Brentwood, CA (Brentwood) 1st Season, UCLA ’06 Megan Lester 5-7 Jr. R La Quinta, CA (La Quinta) Student Managers: Olivia Annacone, Emily Altieri Dominika Matkowska 5-5 Fr. R Szczecin, Poland (Adam Asnyk) Kyle McPhillips 5-5 Fr. R Willoughby, OH (Andrews Osborne Academy) Pamela Montez 5-5 Sr. R La Quinta, CA (La Quinta) Pronunciation Guide Skylar Morton 5-8 So. R Bethesda, MD (Laurel Springs) Courtney Dolehide DOLE-uh-hide Kaitlin Ray 5-4 So. R Little Rock, AR (Kaplan College Prep) Dylan Kirsch Kersh Morgan Thomas 5-6 Jr. R Rolling Hills, CA (Palos Verdes) Dominika Matkowska Dom-in-eeka Chanelle Van Nguyen 5-2 So. R Miami, FL (K12 International Academy) Chanelle Van Nguyen van-WIN 1 2013 UCLA WOMEN’S TENNIS 2013 Coaching Staff Stella SAMPRAS WEBSTER Head Coach 17th Season UCLA ‘91 Career Coaching Record Year Overall Conf. -
Diabetes Complications
Trusted Health Information from the National Institutes of Health ® MedlineNIHFall 2012 Plusthe magazine Preventing & Managing Diabetes Complications Movie and TV Star Anthony Anderson Educating About the Dangers of Diabetes Anthony Anderson and Tempestt Bledsoe star in the new NBC situation comedy, Guys with Kids. Plus! Time to Get Your Steady Advances in Turning the Tide Annual Flu Shot Cystic Fibrosis Research Against AIDS Protect yourself and others NFL star Boomer Esiason and son Elton John and NIH work to end during this flu season16 Gunnar fight CF together4 the AIDS pandemic 2 A publication of the NATIONAL INSTITUTES OF HEALTH and the FRIENDS of the NATIONAL LIBRARY OF MEDICINE FRIENDS OF THE NATIONAL LIBRARY OF MEDICINE qOutgoing FNLM Chairman and Presi- dent Donald West King, MD, received a standing ovation for his many services to FNLM and the Library over the years. 2012 In mid-September, the FriendsAwards held its annual Awards GalaGala to celebrate advances Event! in public health, medicine, and health communications, as well as the individuals and organizations dedicated to these causes. The 2012 Gala brought together representatives from the public, professional, and business sectors in health care to show their support for the Library. Sincerely, Glen P. Campbell, Chairman Friends of the National Library of Medicine uGlen Campbell, FNLM Chairman, receives the Distinguished Health Communications Award for Karen Hunter, Senior Vice President Global Academic & Customer Relations, Elsevier, who was unable to attend. Hunter’s award recognized her for leadership in electronic delivery of information to libraries. Photos: Michael Spencer, NIH Michael Spencer, Photos: pAlfred Sommer (left), MD, MHS, Professor, Johns Hopkins Bloomberg pThe Honorable John Edward Porter (right), former School of Public Health, receives the pAnna Ercoli Schnitzer (center), MLIS, Disabilities Distinguished Medical Science Award Librarian, Taubman Health Sciences Library, University of U.S.