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Covid-19 and Children
COVID-19 AND CHILDREN REPORT OF A SPECIAL TASK FORCE LED BY THE CHIEF SCIENCE ADVISOR OF CANADA July 2020 Office of the Chief Bureau du conseiller Science Advisor of Canada scientifique en chef du Canada TABLE OF CONTENT EXECUTIVE SUMMARY 2 TASK FORCE MEMBERS 4 I. OBJECTIVE 5 Mandate 5 Methodology 5 II. CONTEXT AND STATE OF KNOWLEDGE 6 1. The role of children in the transmission of SARS-CoV-2 7 2. Disease presentation and risk factors in children 9 3. The impact of COVID-19 social measures on children and their families 11 III. FINDINGS 13 IV. ANALYSIS AND FUTURE CONSIDERATIONS 14 A. Children in daycares and schools 14 B. Addressing the challenges of COVID-19 in vulnerable children 16 V. CONCLUSION 17 REFERENCES 18 EXECUTIVE SUMMARY For the past six months, the world has been The key task force findings are: dealing with an unprecedented pandemic caused by a new corona virus: SARS-CoV-2. Much has 1. Children are susceptible to SARS-CoV-2 been learned since on the virus and the illness infection but the disease is generally it causes, COVID-19, but many knowledge gaps milder in children than in older adults for persist on the prevalence, clinical presentation reasons that have not yet been identified. and transmission of COVID-19 in children. 2. Younger children (up to 10 years of age) Children form a unique population that may seem to have lower infection rates than have different infectivity and role in disease older children. The reasons behind this age- transmission compared to adults. -
October 2018 Asbmb Today 1 Editor’S Note
CONTENTS NEWS FEATURES PERSPECTIVES 2 24 48 EDITOR’S NOTE MEET MONA NEMER, PROFESSIONAL DEVELOPMENT Look back and listen CANADA’S TOP SCIENCE ADVISER Policy is your BFF 3 32 50 NEWS FROM THE HILL THE PHOTOSYNTHESIS FIX AFRICAN-AMERICAN MEN Weigh in on initiatives across the NIH IN THE MOLECULAR BIOSCIENCES 41 Managing underrepresentation 4 ANNUAL MEETING MEMBER UPDATE 41 Scientific session snapshots 48 44 Abstract advice 7 46 Abstract topics NEWS 7 Chapter leader finds his niche 24 8 Shadow gene gives otters, manatees susceptibility to banned bug-killer 10 2018 honor society inductees 11 50 LIPID NEWS Studying protein–lipid interactions 12 JOURNAL NEWS 32 12 Scientists sweep cellular neighborhoods where Zika hides out 13 Spectroscopic studies scrutinize links between liver disease and mitochondria 15 Scientists fill in a piece of the copper transport puzzle 16 What bacteria can teach us about combating atrazine contamination 18 Award winners pen essays for JBC 20 From the journals 8 41 OCTOBER 2018 ASBMB TODAY 1 EDITOR’S NOTE THE MEMBER MAGAZINE OF THE AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY Look back and listen By Comfort Dorn OFFICERS COUNCIL MEMBERS Gerald Hart Squire J. Booker President Victoria J. DeRose Wayne Fairbrother n general, and My involvement in Jennifer DuBois Rachel Green especially in this this work was minimal. Secretary Blake Hill space, I like to look Early in the process, Toni M. Antalis Susan Marqusee I Treasurer Celia A. Shiffer ahead. That’s my job. when Allison told us Takita Felder Sumter This week (about two she wanted to make an JoAnn Trejo EX-OFFICIO MEMBERS weeks before you are audio article, I dubbed David Bernlohr ASBMB TODAY EDITORIAL reading these words), it an “audicle” and Hao Wu I am making assign- won a few laughs. -
Older Women's Health Priorities and Perceptions of Care Delivery
Research Recherche Older women’s health priorities and perceptions of care delivery: results of the WOW health survey Cara Tannenbaum, Nancy Mayo, Francine Ducharme ß See related article page 165 Abstract s women’s life expectancy increases, physicians are confronted with the challenge of treating an elderly Background: As women get older, their health priorities change. A population that is predominantly female and has a We surveyed a sample of older Canadian women to investi- variety of health priorities and needs. Older women face gate what health priorities are of concern to them, their per- functional, psychological and social difficulties in addition ceptions about the care delivered to address these priorities to health-related conditions. One solution to align care and the extent to which priorities and perceptions of care dif- more closely with women’s health priorities is to practise fer across age groups and provinces. patient-centred care, whereby clinical decision-making is Methods: The WOW (What Older women Want) cross-sec- focused primarily on the priorities and preferences of indi- tional health survey was mailed in October 2003 to 5000 vidual patients.1–3 Data on older women’s health priorities community-dwelling women aged 55–95 years from 10 4–6 Canadian provinces. Women were asked questions on 26 are scarce, and understanding the gamut of their con- health priorities according to the World Health Organiza- cerns is important for directing patient-centred, priority- tion’s International Classification of Functioning, Disability driven agendas. The WOW — What Older women Want and Health, and their perceptions of whether these priorities — health survey was conducted to determine health priori- were being addressed by health care providers through ties of older Canadian women and the extent to which screening or counselling. -
Effectiveness of Continence Promotion for Older Women Via Community Organisations: a Cluster Randomised Trial
BMJ Open: first published as 10.1136/bmjopen-2013-004135 on 10 December 2013. Downloaded from Open Access Research Effectiveness of continence promotion for older women via community organisations: a cluster randomised trial Cara Tannenbaum,1 Rona Agnew,2 Andrea Benedetti,3 Doneal Thomas,4 Eleanor van den Heuvel5 To cite: Tannenbaum C, ABSTRACT et al Strengths and limitations of this study Agnew R, Benedetti A, . Objectives: The primary objective of this cluster Effectiveness of continence randomised controlled trial was to compare the ▪ promotion for older women First study to provide level 1 evidence that con- effectiveness of the three experimental continence via community organisations: tinence promotion is an effective strategy for a cluster randomised trial. promotion interventions against a control intervention improving urinary symptoms among untreated BMJ Open 2013;3:e004135. on urinary symptom improvement in older women with community-dwelling older women. doi:10.1136/bmjopen-2013- untreated incontinence recruited from community ▪ Participants were recruited via community orga- 004135 organisations. A second objective was to determine nisations with representation across diverse whether changes in incontinence-related knowledge socioeconomic strata. ▸ Prepublication history for and new uptake of risk-modifying behaviours explain ▪ Rates of knowledge acquisition and behaviour this paper is available online. these improvements. change provide an explanatory mechanism for To view these files please Setting: 71 community organisations across the UK. the observed improvements in incontinence in visit the journal online Participants: 259 women aged 60 years and older participants receiving the combined education (http://dx.doi.org/10.1136/ with untreated incontinence entered the trial; 88% plus self-management strategy. -
Debates of the Senate
DEBATES OF THE SENATE 1st SESSION • 42nd PARLIAMENT • VOLUME 150 • NUMBER 155 OFFICIAL REPORT (HANSARD) Thursday, November 2, 2017 The Honourable GEORGE J. FUREY, Speaker CONTENTS (Daily index of proceedings appears at back of this issue). Debates Services: D’Arcy McPherson, National Press Building, Room 906, Tel. 613-995-5756 Publications Centre: Kim Laughren, National Press Building, Room 926, Tel. 613-947-0609 Published by the Senate Available on the Internet: http://www.parl.gc.ca 4050 THE SENATE Thursday, November 2, 2017 The Senate met at 1:30 p.m., the Speaker in the chair. Honourable senators, we have a long list of senators who would like to speak today. In order to get all senators in in the Prayers. time provided, I would ask senators to keep their remarks to two minutes, please. VISITORS IN THE GALLERY Hon. Larry W. Smith (Leader of the Opposition): I would like to congratulate the Honourable Senator Kelvin Ogilvie for The Hon. the Speaker: Honourable senators, I wish to draw his outstanding contribution to Canada in his service as senator, your attention to the presence in the gallery of Indigenous youth as well as in his career prior to his 2009 appointment. delegates and staff of the Nishnawbe Aski Nation. They are the guests of the Honourable Senator Sinclair. What Senator Ogilvie brought to the Senate was his extensive knowledge as well as his fundamental understanding of the On behalf of all honourable senators, I welcome you to the power and evolution of the knowledge economy. He had an Senate of Canada. -
Freeland, Champagne to Balance Canada-US Relationship
Heard on the Hill Foreign Policy Michael Harris Politics Hill Climbers Susan Riley Sheila Copps p. 9 Senate news Energy p. 6 NDP rookie MP Matthew Rose LeMay p. 7 policy briefi ng pp. 19-27 Green making waves p. 4 Hill Times’ 30th shin dig p. 33 THIRTY-FIRST YEAR, NO. 1686 CANADA’S POLITICS AND GOVERNMENT NEWSPAPER MONDAY, DECEMBER 2, 2019 $5.00 Opinion Climate catastrophe was a problem with the climate. In fact, they have gone up 15 per So much for promises of ‘early and deep cent in the past 10 years. So much for the promises of “early and deep cuts” in emissions to avoid catastrophic heating. cuts’ to avoid castrophic climate change Governments have been making these promises since the ONDON, U.K.—What a sur- report by the United Nations is BY GWYNNE DYER emissions are still going up 30 early 1990s, and they are never Lprise! The annual emissions now out, and greenhouse gas years after we fi rst realized there Continued on page 10 News Prime minister News Foreign policy News Legislation New Foreign Affairs Minister Humbled François-Philippe Policy primer: Champagne and Trudeau new Deputy Prime Liberals Minister and changes Intergovernmental promise to Affaris Minister leadership style, Chrystia Freeland, address Impact pictured at but unclear if Rideau Hall on Assessment law Nov. 20, 2019. The Hill Times it’s an ‘actual photographs by outrage without conversion’ or Andrew Meade amendments just a ‘diff erent BY PETER MAZEREEUW role, for now’ overnment offi cials are pol- Gishing off “guidance” docu- ments that experts say could be BY ABBAS RANA used by new Environment Minis- ‘No such thing as too ter Jonathan Wilkinson to make fter dealing with numerous good on his promise to address Ahigh-profi le controversies in criticisms of his government’s his fi rst mandate, being reduced Impact Assessment Act without to a minority government in many cooks’: Freeland, changing the law. -
Canada Report Anke Kessler, Andrew Sharpe, Martin Thunert (Coordinator)
Canada Report Anke Kessler, Andrew Sharpe, Martin Thunert (Coordinator) Sustainable Governance Indicators 2019 © vege - stock.adobe.com Sustainable Governance SGI Indicators SGI 2019 | 2 Canada Report Executive Summary Canada’s economic position is strong, despite lingering barriers to internal trade, high household debt and overheated property markets in major cities. The Canadian government has managed to avoid major economic disruptions during the recent NAFTA renegotiations, but remains at the mercy of an unpredictable U.S. administration. The federal government debt is moderate and sustainable, but the provinces have come under increasing fiscal strain from rising health care costs, which are likely to rise further in the foreseeable future. The government of Prime Minister Trudeau has been praised for its 2018 budget which introduced gender conscious accounting of impacts, expanded parental leave and introduced the Canadian Workers Benefit (a refundable tax credit for low-income earners). The Liberals under Trudeau also expanded benefits under the Canadian Pension Plan, which remains fiscally sound, and recently legalized cannabis, fulfilling a high profile campaign pledge. The government has also been celebrated for its positive messaging toward immigrants and returning Canada to an active role in U.N. peacekeeping operations. On other policy issues, the government has had trouble meeting the high expectations it established during the election campaign and in the early years of its term. Key bills on security oversight, environmental regulation and access to information remain before parliament, but are at risk falling off the agenda if they are not passed before the upcoming federal election in October 2019. Campaign promises notwithstanding, the government has yet to develop a national strategy for childcare and early childhood education. -
Dr. Lynn A. Raymond, MD, Phd, FRCPC, President Dr. Jaideep Bains, Phd, Vice-President Lynn Raymond, MD
th Vancouver, Calgary and Québec city, February 28 , 2018 The Canadian Association for Neuroscience From: Dr. Lynn A. Raymond, MD, PhD, FRCPC, President Dr. Jaideep Bains, PhD, Vice-President Lynn Raymond, MD. Ph.D. President Dr. Katalin Toth, PhD, Chair of the Advocacy Committee, University of British Columbia Canadian Association for Neuroscience To: The Honourable Kirsty Duncan, Minister of Science and Jaideep Bains, Ph.D Minister of Sport and Persons with Disabilities Vice-President The Honourable William Francis Morneau, Minister of University of Calgary Finance Katalin Toth, Ph.D The Right Honourable Justin Trudeau, Prime Minister Chair of the Advocacy Government of Canada Committee Université Laval Edward Ruthazer , Ph.D. Dear Ministers Duncan, Morneau and Trudeau, Secretary As representatives of the largest association of neuroscientists in Canada, we McGill University wish to thank you and applaud the announcement of important new Derek Bowie, Ph.D. financial support for Investigator-led fundamental research in budget 2018. Treasurer McGill University This budget makes significant strides towards the implementation of the recommendations of the Fundamental Science Review, commissioned by the Board of Directors: honourable Kirsty Duncan, and is good news for scientists across the country Freda Miller, Ph.D and all Canadians. Past-President University of Toronto The investments announced today will have a significant impact for all Canadians. Scientific research is among the highest-yield investments that Shernaz Bamji, Ph.D. University of British Columbia the government can make – it provides training for highly qualified personnel and leads to discoveries that improve the lives and health of everyone. Stephanie Borgland, Ph.D. -
Female Grant Applicants Are Equally Successful When Peer Reviewers Assess the Science, but Not When They Assess the Scientist
bioRxiv preprint doi: https://doi.org/10.1101/232868; this version posted March 2, 2018. The copyright holder for this preprint (which was not certified by peer review) is the author/funder. All rights reserved. No reuse allowed without permission. Female grant applicants are equally successful when peer reviewers assess the science, but not when they assess the scientist Holly O. Witteman, PhD1; Michael Hendricks, PhD2; Sharon Straus, MD FRCPC MSc HBSc3; Cara Tannenbaum, MD MSc4 1Associate Professor, Department of Family and Emergency Medicine, Faculty of Medicine, 1050 avenue de la Médecine, Université Laval, Quebec City, Canada, G1V 0A6 2Assistant Professor, Department of Biology, Faculty of Science, 1205 av du Docteur-Penfield, McGill University, Montreal, Canada, H3A 1B1 3Professor, Li Ka Shing Knowledge Institute of St. Michael's Hospital, 30 Bond Street, Toronto, Canada, M3B 2T9 4Scientific Director, Institute for Gender and Health, Canadian Institutes of Health Research, Ottawa, Canada, H3A 1W4 Corresponding author: Holly O. Witteman, 1050 avenue de la Médecine, Pavillon Ferdinand- Vandry, Université Laval, Québec City, Québec, Canada, G1V 0A6, telephone: 418.656.2131 x3981, fax: 418.656.2465, email: [email protected] Keywords (MeSH terms): Peer Review, Research/methods; Sex Factors Keywords (non-MeSH terms): Gender Bias Running title: Gender Bias in Grant Review Word count: 3500 words bioRxiv preprint doi: https://doi.org/10.1101/232868; this version posted March 2, 2018. The copyright holder for this preprint (which was not certified by peer review) is the author/funder. All rights reserved. No reuse allowed without permission. ABSTRACT (299 words) Background: Previous research shows that men often receive more research funding than women, but does not provide empirical evidence as to why this occurs. -
For Peer Review Only
BMJ Open BMJ Open: first published as 10.1136/bmjopen-2013-004135 on 10 December 2013. Downloaded from Effectiveness of continence promotion for older women via community organisations: a cluster randomised trial ForJournal: peerBMJ Open review only Manuscript ID: bmjopen-2013-004135 Article Type: Research Date Submitted by the Author: 27-Sep-2013 Complete List of Authors: Tannenbaum, Cara; Université de Montréal, Faculty of Medicine Agnew, Rona; Glasgow Caledonian University, Benedetti, Andrea; McGill University, Departments of Medicine and of Epidemiology, Biostatistics & Occupational Health Thomas, Doneal; McGill University, Departments of Medicine and of Epidemiology, Biostatistics & Occupational Health van den Heuvel, Eleanor; Brunel University, <b>Primary Subject Urology Heading</b>: Secondary Subject Heading: Geriatric medicine Keywords: Urinary incontinences < UROLOGY, PUBLIC HEALTH, GERIATRIC MEDICINE http://bmjopen.bmj.com/ on September 24, 2021 by guest. Protected copyright. For peer review only - http://bmjopen.bmj.com/site/about/guidelines.xhtml Page 1 of 35 BMJ Open BMJ Open: first published as 10.1136/bmjopen-2013-004135 on 10 December 2013. Downloaded from 1 2 3 4 5 Effectiveness of continence promotion for older women via community organisations: 6 a cluster randomised trial 7 8 9 1 2 3 10 Cara Tannenbaum, MD, MSc Rona Agnew, PhD Andrea Benedetti, PhD Doneal 11 Thomas, MSc4 Eleanor van den Heuvel, PhD5 12 13 14 1 15 AssociateFor Professor, peer Faculty of Medicine, review Université de Montréal, only Quebec, Canada 16 -
Reduction of Inappropriate Benzodiazepine Prescriptions Among Older Adults Through Direct Patient Education the EMPOWER Cluster Randomized Trial
Research Original Investigation Reduction of Inappropriate Benzodiazepine Prescriptions Among Older Adults Through Direct Patient Education The EMPOWER Cluster Randomized Trial Cara Tannenbaum, MD, MSc; Philippe Martin, BSc; Robyn Tamblyn, PhD; Andrea Benedetti, PhD; Sara Ahmed, PhD Supplemental content at IMPORTANCE The American Board of Internal Medicine Foundation Choosing Wisely jamainternalmedicine.com Campaign recommends against the use of benzodiazepine drugs for adults 65 years and older. The effect of direct patient education to catalyze collaborative care for reducing inappropriate prescriptions remains unknown. OBJECTIVE To compare the effect of a direct-to-consumer educational intervention against usual care on benzodiazepine therapy discontinuation in community-dwelling older adults. DESIGN, SETTING, AND PARTICIPANTS Cluster randomized trial (EMPOWER [Eliminating Medications Through Patient Ownership of End Results] study [2010-2012, 6-month follow-up]). Community pharmacies were randomly allocated to the intervention or control arm in nonstratified, blocked groups of 4. Participants (303 long-term users of benzodiazepine medication aged 65-95 years, recruited from 30 community pharmacies) were screened and enrolled prior to randomization: 15 pharmacies randomized to the educational intervention included 148 participants and 15 pharmacies randomized to the “wait list” control included 155 participants. Participants, physicians, pharmacists, and evaluators were blinded to outcome assessment. INTERVENTIONS The active arm received -
Canadian Science Meets Parliament: Building
Science and Public Policy, 2020, 1–4 doi: 10.1093/scipol/scz062 Perspective Canadian Science Meets Parliament: Building relationships between scientists and Downloaded from https://academic.oup.com/spp/advance-article-abstract/doi/10.1093/scipol/scz062/5710706 by guest on 26 March 2020 policymakers Jiaying Zhao1,*, Meghan B. Azad 2, Erin M. Bertrand3, Cole Burton 4, Valorie A. Crooks5, Jackie Dawson6, Adam T. Ford 7, Angela Kaida8, Arjun Krishnaswamy9, Chikin Kuok10, Catherine L. Mah11, Matt McTaggart12, Amanda J. Moehring 13, Dominique Robert14, Albrecht Schulte-Hostedde 15, Heather Sparling16, Mary A. De Vera17, Stephanie Waterman18 and Trushar R. Patel 19,* 1Canada Research Chair in Behavioural Sustainability, University of British Columbia, Vancouver, BC, Canada, 2Canada Research Chair in the Developmental Origins of Chronic Disease, University of Manitoba, Winnipeg, MB, Canada, 3Canada Research Chair in Marine Microbial Proteomics, Dalhousie University, Halifax, NS, Canada, 4Canada Research Chair in Terrestrial Mammal Conservation, University of British Columbia, Vancouver, BC, Canada, 5Canada Research Chair in Health Service Geographies, Simon Fraser University, Burnaby, BC, Canada, 6Canada Research Chair in Environment, Society, and Policy, University of Ottawa, Ottawa, ON, Canada, 7Canada Research Chair in Wildlife Restoration Ecology, University of British Columbia, Kelowna, BC, Canada, 8Canada Research Chair in Global Perspectives in HIV and Sexual and Reproductive Health, Simon Fraser University, Burnaby, BC, Canada, 9Canada