Person Specification s31

Last updated: JOB DESCRIPTION

Post title: Research Fellow Academic Unit/Service: Human Development and Health Faculty: Medicine Career Pathway: Education, Research and Enterprise (ERE) Level: 4 *ERE category: Research Pathway Posts responsible to: Professor of Genomics Posts responsible for: Junior members of staff and postgraduate students Post base: Office-based

Job purpose This position will support research into medical genomics and will specifically underpin the strategic relationship formed to advance the Wessex Genomics Hub (UoS, UHS and SDH).

Key accountabilities/primary responsibilities % Time 1. Investigate aspects of genomics variation with regards to clinical characteristics 25 % 2. Manage large scale NGS datasets including assessment of quality and platform evaluation. 20 % 3. Develop and validate novel methods for medical genomics 10 % 4. Prepare drafts of manuscripts for publication and reports for multidisciplinary meetings. Present 20 % work at local, national and international meetings 5. Contribute to undergraduate and postgraduate education 20% 6. Communicate with collaborators effectively 5 %

Internal and external relationships  Human Genetics and Genomic Medicine Group, HDH Academic Unit  Wessex Genomics Hub (WISH Lab)  Wessex GMC and local GeCIPS

Special Requirements  Excellent programming and data analysis skills are essential, as is experience of working with large- scale NGS data in a clinical setting.  Applications will be considered from candidates who are working towards or nearing completion of a relevant PhD qualification. The title of Research Fellow will be applied upon completion of PhD. Prior to the qualification being awarded the title of Senior Research Assistant will be given.

PERSON SPECIFICATION

How to be Criteria Essential Desirable assessed Qualifications, PhD in a relevant subject (e.g. Success in attracting external funding Application/CV knowledge and Genomics, Bioinformatics) or experience equivalent professional qualifications and experience Firm grounding in statistical methods. Strong track record in preparing

0704369669ec99db75fa93de56b89975.docxERE Level 4 – Research Pathway – Research Fellow 1 publications and other written materials. Previous experience in working with large scale (empirical and/or simulated) datasets. Experience in working with human genome sequence data. Experience analysing exome and targeted NGS data. Experience of development NGS bioinformatics analytical pipelines. Experience of interrogation and interpretation of data in the context of medical genetics. Excellent scripting/programme skills (R, Perl, C, C++). Knowledge of annotation, assembly and mapping tools Familiarity with online human gene resources and databases

Planning and Effective time management and project Appreciation of QA issues in organising planning/scheduling skills diagnostics Attention to detail and ability to work to tight timelines Demonstrable project management and organisational skills

Excellent report writing skills

Scrupulous attention to detail and data quality issues Problem solving Ability to use own initiative and solve and initiative analytical problems Ability to interpret results given biological hypotheses

Ability to generate independent ideas and directions of new research

0704369669ec99db75fa93de56b89975.docxERE Level 4 – Research Pathway – Research Fellow 2 Management Able to work as an efficient and Experience in supervising and guiding and teamwork communicative member of the team junior research staff and be expected to share expertise with other group members

Capacity to contribute to internal training and teaching as required

Experience working within a diverse interdisciplinary team Communicating Ability to communicate effectively with and influencing collaborators both internally and externally

Able to foster excellent working relationships with colleagues

Excellent communication skills, both written and oral Other skills and A desire to achieve excellence in behaviours research

Special requirements

0704369669ec99db75fa93de56b89975.docxERE Level 4 – Research Pathway – Research Fellow 3 JOB HAZARD ANALYSIS

Is this an office-based post?

☒ Yes If this post is an office-based job with routine office hazards (eg: use of VDU), no further information needs to be supplied. Do not complete the section below.

☐ No If this post is not office-based or has some hazards other than routine office (eg: more than use of VDU) please complete the analysis below. Hiring managers are asked to complete this section as accurately as possible to ensure the safety of the post-holder.

## - HR will send a full PEHQ to all applicants for this position. Please note, if full health clearance is required for a role, this will apply to all individuals, including existing members of staff.

Occasionally Frequently Constantly ENVIRONMENTAL EXPOSURES (<30% of time) (30-60% of time) (> 60% of time) Outside work Extremes of temperature (eg: fridge/ furnace) ## Potential for exposure to body fluids ## Noise (greater than 80 dba - 8 hrs twa) ## Exposure to hazardous substances (eg: solvents, liquids, dust, fumes, biohazards). Specify below: Frequent hand washing Ionising radiation EQUIPMENT/TOOLS/MACHINES USED ## Food handling ## Driving university vehicles(eg: car/van/LGV/PCV) ## Use of latex gloves (prohibited unless specific clinical necessity) ## Vibrating tools (eg: strimmers, hammer drill, lawnmowers) PHYSICAL ABILITIES Load manual handling Repetitive crouching/kneeling/stooping Repetitive pulling/pushing Repetitive lifting Standing for prolonged periods Repetitive climbing (ie: steps, stools, ladders, stairs) Fine motor grips (eg: pipetting) Gross motor grips Repetitive reaching below shoulder height Repetitive reaching at shoulder height Repetitive reaching above shoulder height PSYCHOSOCIAL ISSUES Face to face contact with public Lone working ## Shift work/night work/on call duties

0704369669ec99db75fa93de56b89975.docxERE Level 4 – Research Pathway – Research Fellow 4