CURRICULUM VITAE Lixing Lao, Phd, MB, L.Ac. President

CURRICULUM VITAE

Lixing Lao, PhD, MB, L.Ac. President Virginia University of Integrative Medicine 9401 Mathy Drive, Fairfax, VA 22031 Website: https://www.vuim.edu Tel: (703) 323 5690 ext. 108 Fax: (703) 323 5692 Email: [email protected] Cellphone: (703) 501 8833

EDUCATION

1978 – 1983 M.B. Traditional Chinese Medicine and Acupuncture, Shanghai University of Traditional Chinese Medicine, Shanghai, China 1987 – 1992 Ph.D. Physiology, University of Maryland at Baltimore, Baltimore, Maryland

Post Graduate Training

1982 – 1983 Internship: Shanghai University of Traditional Chinese Medicine, Shanghai, China 1983 – 1986 Residency: Shanghai University of Traditional Chinese Medicine, Shu-Guang Hospital, Shanghai, China

CERTIFICATIONS

1990 – Present Diplomat in Acupuncture, National Certification Commission for Acupuncture and Oriental Medicine (NCCAOM) Provider #: ACHB426-097 (NCCAOM ID: 2286) 1998 – Present Diplomat in Chinese Herbology, National Certification Commission for Acupuncture and Oriental Medicine (NCCAOM) Provider #: ACHB426-097 (NCCAOM ID: 2286) 2005 – Present Diplomat in Oriental Medicine, National Certification Commission for Acupuncture and Oriental Medicine (NCCAOM), Provider #: ACHB426-097 (NCCAOM ID: 2286)

ACUPUNCTURE LICENSURES

1988.3.21 – Present Maryland Board of Acupuncture U-00300 (Exp. 11/30/2021) 2013.9 – 2019.10 Hong Kong, Limited registration for Chinese Medicine Practice (LR0708) 2019.12.4-Present Virginia Board of Medicine, Licensed Acupuncturist (# 0121000955) (Exp. 06/30/2021)

PROFESSIONAL EXPERIENCE AND EMPLOYMENT

1983-1986 Teaching Faculty, Department of Acupuncture, Shanghai College of Traditional Chinese Medicine, Shanghai, P. R. China. 1988-1992 Graduate Research Assistant, Department of Physiology, Dental School, University of Maryland at Baltimore, MD. 1992 Research Associate, Department of Anesthesiology, University of Maryland at Baltimore 1992-2002 Teaching Faculty (part-time), Maryland Institute of Traditional Chinese Medicine. Bethesda, MD. 1992-1994 Research Assistant Professor, Department of Anesthesiology, University of Maryland at Baltimore, MD. 1994-1998 Research Assistant Professor, Complementary Medicine Program, Department of Family Medicine, University of Maryland, Baltimore, MD. 1994-2001 Clinic Director, MITCM Clinic, Maryland Institute of Traditional Chinese Medicine. Bethesda, MD. 1994-2001 Chairperson, Dept. of Clinical Training, Maryland Institute of Traditional Chinese Medicine. Bethesda, MD. 1996 Research Acupuncturist, Clinical trial of the effect of acupuncture on HIV neuropathy, Baltimore Trial, Baltimore, MD. 1998-2000 Assistant Professor, Complementary Medicine Program, Department of Family Medicine, University of Maryland, Baltimore, MD. 1998-2000 Complementary Medicine Clinic Director, Kernan Hospital, Baltimore, MD. 1999 Acting Academic Dean, Maryland Institute of Traditional Chinese Medicine. Bethesda, MD. 2000-2013 Director, Traditional Chinese Medicine Research Program, Center for Integrative Medicine, University of Maryland School of Medicine, Baltimore, MD. 2000-2007 Associate Professor, Center for Integrative Medicine, University of Maryland School of Medicine, Baltimore, MD, USA. 2002-Present Guest Professor, Shanghai University of Traditional Chinese Medicine, Shanghai, P. R. China. 2007-2013 Professor, Center for Integrative Medicine, Department of Family and Community Medicine, University of Maryland School of Medicine, Baltimore, MD., USA 2008-Present Adjunct Faculty, Doctoral Program, American College of Traditional Chinese Medicine, San Francisco, CA, USA 2011-2012 President, Virginia University of Oriental Medicine, Fairfax, VA 2011-2016 Oversea Distinguish Professor, Beijing University of Chinese Medicine, Beijing, China 2012-2014 Oversea Distinguish Professor, Shanghai University of Chinese Medicine, Shanghai, China 2013-Present Member, Board of Trustee, Virginia University of Oriental Medicine, Fairfax, VA 2013.9-2019.10 Professor and Director, School of Chinese Medicine, University of Hong Kong, Hong Kong, China 2013-present Adjunct Professor, Department of Family and Community Medicine, University of Maryland School of Medicine, Baltimore, MD. USA, 2014-2019.10 Endowed Professor, Vivian Taam Wong Professorship in Integrative Medicine, University of Hong Kong, Hong Kong, China 2019.10-Present Honorary Professor, School of Chinese Medicine, University of Hong Kong, Hong Kong, China

A CADEMIC AND PROFESSIONAL CONTRIBUTIONS 1987-1993 Member, IADR Neuroscience Group 1989-1993 Member, American Association of Acupuncture and Oriental Medicine 1989-1997 Member, Maryland Acupuncture Society; Co-Chair, Continuing Education Committee (1995-1997) 2

1990-2001 Board Member, Board of Directors, Maryland Institute of Traditional Chinese Medicine 1993 Faculty, American Academy of Medical Acupuncture Annual Symposium 1994-1999 Board Member, State of Maryland Board of Acupuncture 1995-present Advisory Board; Editorial Board, the Journal of Alternative Therapies in Health and Medicine 1997-present Authorized CNT Instructor, Council of Colleges of Acupuncture and Oriental Medicine (CCAOM) 1998-2010 Board Member, Society for Acupuncture Research (SAR) 1998-present Reviewer, Journal of Alternative and Complementary Medicine (JACM) 1999-2012 Member, Society for Neuroscience 1999- 2004 Member, Editorial Advisory Board; the Journal of Clinical Acupuncture and Oriental Medicine 2000- Present Invited Member of Site Visit Team, Accreditation Commission of Acupuncture and Oriental Medicine (ACAOM) 2001-2005 Board Member, PDQ Cancer CAM Editorial Board, National Cancer Institute (NCI), National Institutes of Health (NIH) 2002 – 2007 Member, Executive Committee, Howard County Chinese School (HCCS) 2003- 2017 Editorial Board Member, the Journal of Alternative and Complementary Medicine (JACM) 2003- 2007 Co-President, Society for Acupuncture Research (SAR) 2004- 2007 Vice President, Traditional Chinese Medicine Association & Alumni (TCMAA) 2004- 2007 Editorial Board Member, American Journal of Traditional Chinese Medicine 2004- present Member, International Society for Chinese Medicine, Macao, China 2005- 2007 Advisory Board Member, International Advisory Board, International Journal of Clinical Acupuncture 2005-present Advisory Board Member, PDQ Cancer CAM Advisory Board, National Cancer Institute (NCI), National Institutes of Health (NIH) 2005- 2013 Editorial Board Member, Journal of Chinese Integrative Medicine, China 2005- present Editorial Board Member, Chinese Medicine Journal (CMJ), China 2005- present Editorial Board Member, Journal of the Society for Integrative Oncology (JSIO) 2005-present Member of Organizing Committee, Building Bridges of Integration for TCM, TCM World Foundation 2007- 2010 Treasurer, Society for Acupuncture Research (SAR) 2007- present Committee Member, Expert Committee, World Federation of Acupuncture-Moxibustion Societies (WFAS) 2008- present Editorial Board Member, Chinese Acupuncture & Moxibustion (Chinese version) 2009- 2014 Associate Editor, the Journal of Alternative and Complementary Medicine (JACM) 2009-2011 Editor-in-Chief, American Acupuncturist, American Association of Acupuncture and Oriental Medicine (AAAOM) 2010 – 2012 Board Member and Vice Chair, Board of Directors, Howard County Chinese School (HCCS) 2010 - presentEditor, Evidence-Based Complementary and Alternative Medicine (ECAM) 2011- 2013 Senior Editor, American Acupuncturist, American Association of Acupuncture and Oriental Medicine (AAAOM) 2013- present Editor-in-Chief, Journal of Integrative Medicine (JIM), China (SCI; IF: 2.44 in 2019) 2013 - presentVice President,, World Federation of Acupuncture-Moxibustion Societies (WFAS) 2013 – 2019 Secretary General, Consortium for Globalization of Chinese Medicine (CGCM)

2014 Patent (3907874): A flexible device for research animal holding. #ZL 2014 2 0065468.4 via Beijing University. By China Intellectual Property Department, Beijing, China 2020-present Board Member, Society for Acupuncture Research (SAR)

Committees and Professional Contributions in Hong Kong (2013-2019) 1. Board member, Chinese Medicine Council of Hong Kong (香港中醫藥管理委員會) 2. Board member, Chinese Medicine Practitioners Board (香港中醫藥管理委員會中醫業小組) 3 . Board member, Chinese Medicines (herbs) Board (香港中醫藥管理委員會中藥業小組委員會) 4. Member, Heavy Metal in Chinese Medicines Working Group (香港中醫藥管理委員會修訂中成藥重金屬及有毒元素標準工作小組) 5. Board member, Chinese Medicine Development Committee, Food and Health Bureau (食物及衞生局, 中醫中藥發展委員會) 6. Member, Chinese Medicine Hospital Planning User Committee, , Food and Health Bureau (食物及衞生局, 中醫醫院發展計劃辦事處, 中醫醫院籌劃使用者委員會) 7. Member, Research and Development Committee of Chinese Medicine, Innovation and Technology Department (創新科技署, 中藥研究及發展委員會) 8. Board member, Central Committee of Chinese Medicine, Hospital Authority (醫院管理局, 中醫中央委員會) 9. Board member and Chairperson, Hong Kong Working Group on the Development of Chinese Medicine (香港中醫專科發展工作組) 10. Board member, Hospital Authority, Hong Kong West Cluster Integrated Chinese-Western Medicine (HKWC ICWM) 11. Board member, Hong Kong Buddhist Association – The University of Hong Kong Clinical Centre for Teaching and Research in Chinese Medicine: Clinical Management Committee 12. Board member, The Hong Kong Tuberculosis Association Chinese Medicine Clinic cum Training Centre of The University of Hong Kong: Clinical Management Committee 13. Board member, The Hong Kong Tuberculosis Association-The University of Hong Kong Clinical Centre For Teaching and Research in Chinese Medicine (Aberdeen): Clinical Management Committee 14. Board member, Tung Wah Hospital – The University of Hong Kong Clinical Centre for Teaching and Research in Chinese Medicine: Clinical Management Committee 15. Board member, Yan Oi Tong - The University of Hong Kong Chinese Medicine Centre forTraining and Research (Tung Chung) 16. Member, Clinical Trial Centre Management Committee, University of Hong Kong 17. Chairman, Board of Studies, part-time degree ofMaster of Chinese Medicine in Acupuncture and Moxibustion (MChinMed (Acup & Mox)) 18. Chairman, Board of Studies, part-time degree of Master of Chinese Medicine in the stream of Chinese Medicine (MChinMed) 19. Chairman, Board of Studies, part-time degree of Master of Science in Chinese Medicine (MScChinMeds) 20. Chief Examiner, Board of Examiner, part-time degree of Master of Chinese Medicine in the stream of Chinese Medicine (MChinMed) 21. Chief Examiner, Board of Examiner, part-time degree of Master of Chinese Medicine in Acupuncture and Moxibustion (MChinMed (Acup & Mox)) 22. Chief Examiner, Board of Examiner, part-time degree of Master of Science in Chinese Medicine (MScChinMeds) 23. Chief Examiner, Board of Examiner, full-time degree of Bachelor of Chinese Medicine programme (BChinMed) 24. Course Co-ordinator of BCHM2607 Medical Ethics and Professionalism in Chinese Medicine 4

Practice (醫學倫理學及中醫專業操守), full-time degree of Bachelor of Chinese Medicine programme (BChinMed) HONORS AND AWARDS 1980 Shanghai University of TCM Merit Award, Shanghai, China 1981 First Prize Scholarship of Shanghai Bureau of Higher Education, Shanghai, P. R. China 1982 First Prize Scholarship of Shanghai Bureau of Higher Education, Shanghai, P. R. China 1987 – 1991 Graduate School Merit Award, University of Maryland, Baltimore, MD 1988 – 1992 NIH Research Assistantship, Department of Physiology, Dental School, University of Maryland, Baltimore, MD 1990 – 1991 Merit Award of The National Dean's List 2002 – Present Guest Professor, College of Acupuncture and Tui Na, Shanghai University of Traditional Chinese Medicine, Shanghai, P. R. China. 2003 Award for outstanding contribution in TCM, by People’s Republic of China, Chinese TCM Association, Beijing, China 2004 May Award for outstanding service to the acupuncture and Oriental medicine profession in the field of research and to the community at-large by the AOM Alliance, Los Angles, CA 2004 – 2006 Who’s Who in Medicine and Healthcare 2005 October Award of the Year by Building Bridges of Integration for TCM. East Rutherford, NJ 2007 November Award of serving co-president of the Society for Acupuncture Research (SAR) from 2003 through 2007, Baltimore, MD 2010 Baltimore Magazine Top Doctors of 2010 in Alternative/Complementary Medicine 2014 Chen HY, Feng Y and Lao L. Chinese Medicine Higher Education Paper Award (Second Prize), National CM Higher Education Association (CMEA) 2 015 Qi-Huang International Award (岐黄国际奖), China Association of Chinese Medicine 2016 Science and Technology Award (Third Class), Shanghai Government, China 2018 Science and Technology Award (Third Class), China Association of Chinese Medicine 2019 Chief Executive’s Commendation for Community Service. The Government of the Hong Kong Special Administrative Region (SAR), China

PUBLIC ADVISORY SERVICE: STUDY SECTION REVIEWER NIH Public Health Service, Study Section on ZRG1 MOSS-K(11) Special Emphasis Panel. Small Business: Oral, Dental C raniofacial Sciences, Internet Assisted Meeting (July, 2012) NIH Public Health Service, NCCAM, Study Section on Partnerships for Complementary Alternative Medicine (CAM) Clinical Translational Research PCCTR U19 CAM Study Section - Reviewer, MD (February, 2012) Hong Kong Research Grant Council (RGC) External Reviewer Since 2010 NIH Public Health Service, NCCAM, Special Emphasis Panel/Scientific Review on PCCTR U19 CAM Study Section - Reviewer, Gaithersburg, MD (November, 2009) NIH Public Health Service, ZRG1 Study Section – Mail-in Reviewer (May, 2009) NIH Public Health Service, NCCAM, HM Study Section Reviewer (February, 2009) 5

NIH Public Health Service, VCMB Study Section Reviewer (July, 2008) NIH Public Health Service, MRS Study Section Reviewer (February, 2008) NIH Public Health Service, NCCAM, Special Emphasis Panel/Scientific Review on Centers of Excellence for Research on CAM Study Section - Reviewer, Gaithersburg, MD (November, 2007) NIH Public Health Service, BMIO Study Section – Reviewer, Tysons Corner, VA (June, 2007) NIH Public Health Service, NCCAM, Special Emphasis Panel/Scientific Review on Mechanisms of Immune Modulation Study Section - Reviewer, Bethesda, MD (March, 2007) NIH Public Health Service, Musculoskeletal Rehabilitation Sciences Study Section - Consultant, Washington, DC (Nov. 2006) Dept. of Veterans Affairs, RR&D Scientific Merit Review Board – Reviewer, Washington, DC (August, 2006) Dept. of Veterans Affairs, RR&D Scientific Merit Review Board – Reviewer, Arlington, VA (March, 2006) NIH Public Health Service, BMIO Study Section – Consultant/Discussant, MD (February, 2006) NIH Public Health Service, BMIO Study Section – Consultant/Discussant, Annapolis, MD (February, 2005) NIH Public Health Service, RPHB-B panel Mind-Body Study Section – Reviewer, Washington DC (June, 2004) NIH Public Health Service, BMIO Study Section – Consultant, Baltimore, MD (October, 2003) NIH Public Health Service, Experimental Cardiovascular Sciences Study Section – Consultant, Bethesda, MD (August, 2003) NIH Public Health Service, NCCAM Special Emphasis Panel Grant Study Section – Reviewer, Bethesda, MD (July, 2003) NIH National Cancer Institute (NCI), Board Member of PDQ Cancer CAM Editorial Board (2001-present) NIH Public Health Service NCI Cancer Center Support Grant Study Section – Reviewer, Bethesda, MD (February, 2001) NIH Public Health Service Geriatrics and Rehabilitation Medicine Study Section – Reviewer, Bethesda, MD (March, 2000) NIH Public Health Service Geriatrics and Rehabilitation Medicine Study Section – Reviewer, Bethesda, MD (November, 2000) NIH Public Health Service Special Study Section – Acupuncture Reviewer, Bethesda, MD (March, 1999) NIH Public Health Service Cardiovascular and Renal Study Section – Reviewer, Chevy Chase, MD (October, 1998) NIH Department of Health and Human Services – Reviewer, General Medicine A-2 Study Section. Bethesda, MD (September, 1998) U.S. House of Representatives Committee on Resources. Testified regarding the use of endangered species in Chinese medicines for the Rhinoceros and Tiger Conservation Act. (February, 1998)

GRANT SUPPORT Total Active Grant Support S ystematic Review on Integrated Western Medicine and Chinese Medicine Interventions for Breast Cancer Integrative Joint Organizational Platform from the Hong Kong Association for Integration of Chinese-Western Medicine Grant #: IJOP-0001-0003 (2019-2020)

Role: Principal-investigator, 10%effort (No salary requested) $150,000(HKD)

The effect of acupuncture for insomnia in breast cancer patients undergoing chemotherapy a randomized, sham-controlled trial Health and Medical Research Fund (05/01/2019-04/30/2022) Grant #:16172761 Role: Principal-investigator, 25%effort (No salary requested) $1,500,000(HKD)

WHO technical document on clinical research in traditional and complementary medicine World Health Organization (02/2018-present) Grant #:Nil Role: Principal-investigator, 5%effort (No salary requested) $46,902(HKD)

Completed Grant Support Development of a Novel Auriculotherapy Device for Pain Management Seed Fund for Translational and Applied Research (06/01/2016-11/30/2019) Grant #:201711160034; Role: Principal-investigator, 10%effort (No salary requested) $150,000(HKD)

Combined Electroacupuncture and Auricular Acupuncture for Postoperative Pain after Abdominal Surgery for Gynecological Diseases: A Randomized Sham-controlled Trial Health and Medical Research Fund (07/01/2016-06/30/2019) Grant #:13142951 Role: Principal-investigator, 25%effort (No salary requested) $761,707(HKD)

A Randomized, Wait-list Controlled Trial of Self-administered Acupressure for Symptom Management Among Chinese Family Caregivers with Caregiver Stress Health and Medical Research Fund (07/01/2016-06/30/2018) Grant #: 13143191 Role: Co-investigator, 10% effort (No salary requested) $1,000,000(HKD)

Electroacupuncture for tapering off long-term benzodiazepine use: a randomized controlled trial Health and Medical Research Fund (06/01/2015-05/31/2017) Grant #:12133661 Role: Co-investigator, 10% effort (No salary requested) $917,030(HKD)

A double-blind, randomized, two-dose trial of Tumor-shrinking Decoction (TSD), a Chinese medicine preparation in patients with symptomatic uterine fibroids Health and Medical Research Fund (04/01/2014-03/31/2016) Grant #:11121841

Role: Co-investigator, 10% effort (No salary requested) $994,600 (HKD)

Development of Chinese Medicine Acupuncture Clinical Practice Guideline in Low Back Pain Grant #: HA105/48 PT 19 (2013/14) Role: Principal Investigator, 100% effort (No salary requested) $400,000(HKD)

Development of Guideline for Research Methodology on Acupuncture Grant #: HA105/48 PT18 (2013/14) Role: Principal Investigator, 100% effort (No salary requested) $350,000(HKD)

Acupuncture Sharing Forum (2014) Grant #: HA105/48 PT18 Role: Principal Investigator, 100% effort (No salary requested) $2900(HKD)

Effects and Neurobiological Mechanisms of Traditional Moxibustion-based Laser Moxibustion with Specific Wavelength on Inflammatory Pain Nature and Science Foundation China (NSFC) (01/01/2013 – 12/31/2018) Grant #: 81320108028 Role: Co-Principal Investigator (PI: Xueyong Shen) ¥2,800,000(RMB)

Cochrane Collaboration CAM Field – Resource for Research NIH NCCAM (7/1/2013 – 06/30/2017, renewed from 2003) Grant # 2 R24 AT001293-02, Role: Co-Investigator, (PI: Brian Berman) 10% effort $3,000,000

Acupuncture to Prevent Chemotherapy Dose Reduction National Cancer Institute, NIH (02/2013-01/2015) Grant # R21 CA173263-01 Role: Co-Investigator, (PI: Ting Bao) 2% effort $206,625

Antinociceptive effects of electroacupuncture on persistent inflammatory pain via spinal adiponectin-dependent pathway to suppress neuroinflammation and central sensitization in animal models Seed Fund for Basic Research for Resubmission of GRF/ECS Proposals (07/01/2018-11/30/2018) Grant #:13142951 Role: Principal investigator, 15% effort $56,000(HKD)

Effect of Acupuncture on Postoperative Oral Surgery Pain N ational Institutes of Health, September 1994 – September 1997 Grant #: 1 R21 RR09519-01 Role: Principal investigator, 15% effort $44,030

Effect of Acupuncture on Osteoarthritis R21, Grant # 1 R21 RR09327-01 National Institutes of Health, September 1994 - December 1995 Principal Investigator: Brian M. Berman, M.D. Role: Co-investigator, 10% effort $44,550

The Effect of Electroacupuncture on Cyclophosphamide-induced Emesis in Ferrets U. S. Department of the Army - Breast Cancer Research Program, July 1994 - July 1996 Grant #: DAMD 17-94-J-4325 Role: Principal investigator, 20% effort $150,000

Acupuncture Safety/Efficacy in Knee Osteoarthritis (RO1) NIH National Center for Complementary and Alternative Medicine, September 1998 – October 2002, Grant #: UO1 AT00171 Principal Investigator: Brian M. Berman, M.D. Role: Co-investigator, 15% effort $2,552,819

Use of Acupuncture for Dental Pain: Testing a Model NIH National Center for Complementary and Alternative Medicine; 1998-2002, Grant #: 8 RO1 AT00010 Role: Principal investigator, 25% effort $1,086,027

University of Maryland DRIF Funding – The Analgesic and Anti- Inflammatory Effects of Acupuncture in the Rat (1998 – 1999) Role: Principal investigator, 25% effort $14,933

A Controlled Study Using Acupuncture as an Adjuvant to Treat Chemotherapy- Induced Nausea and Vomiting U.S. Department of the Army, July 1999 – June 2002 Grant #: BC980536 Role: Principal investigator, 20% effort $257,342

University of Maryland DRIF Funding – The Effect of Electroacupuncture on Peripheral Opioids Release (1999 – 2000) Role: Principal investigator, 15% effort $14,860

The effect of electroacupuncture on peripheral opioid release R21, NCCAM, NIH, September 2000 - June 2002 Principal Investigator: Grant Zhang, Ph.D. Role: Co-investigator, 10% effort $352,844

Consistency of TCM RA Diagnosis and herbal prescription R21, NCCAM, NIH, July 2001 to June 2003 Principal Investigator: Grant Zhang, Ph.D. Role: Co-investigator, 10% effort $308,250

Center for Complementary and Alternative Medicine Research 9 of Arthritis, Project #3: The Effects of Electro Acupuncture on Persistent Inflammation Pain in the Rat. NIH National Center For Complementary and Alternative Medicine (1999-2004) Grant # 1 P50 AT00084-01 Role: Principal investigator, 25% effort $679,701

Effects of Acupuncture on Bone Cancer Pain in Mice R21, NCI, NIH, August 2003 to July 2005 Principal Investigator: Ruixin Zhang, Ph.D. Role: Co-investigator, 10% effort $368,486

Planning Grant for International Centers for Research on CAM (PICRC) Grant # R21, AT001943-01NCCAM, NIH, September 2003 to August 2005 Principal Investigator: Brian M. Berman, M.D. Role: Co-investigator, 5% effort

OCT-Guided Intervention for Pain Management Grant # RO1 EB04057 NIBIB (7/1/2004 to 6/30/2008) Role: Co-Investigator, (PI: Cha-Min Tang). 0% effort $1,062,903

The Status and Future of Acupuncture Research: 10 years post-NIH Consensus Conference Grant # R13 AT004143-01, Agency: NCCAM, NIH 5/1/07-4/40/08) Role: Principal Investigator, 3% effort $62,505

Acupuncture for Infertility Patients: The Effects of IVF Grant # R21 AT002651-01A1, NCCAM, NIH, 9/15/05 - 8/31/08 Role: Co-Investigator, (PI: Grant Zhang). 5% effort $594,000

Center for Arthritis and Traditional Chinese Medicine (TCM) NIH National Center For Complementary and Alternative Medicine (9/2005 -- 8/2010) Grant # 1 P01 AT002605-01A1 R ole: Co-Principal Investigator, (PI: Brian Berman) 30% effort $6,140,311

Project 2: Mechanisms of Acupuncture's Effect on Inflammatory Pain Under the Center for Arthritis and Traditional Chinese Medicine (TCM) NIH National Center For Complementary and Alternative Medicine (9/2005 -- 8/2010) Grant # 1 P01 AT002605-01A1 Role: Project Leader, (PI: Brian M. Berman, Co-PI: Lixing Lao), 20% effort $790,431

Project 1: Dose Escalation Study of Chinese Herbs in Osteoarthritis of the Knee. Under the Center for Arthritis and Traditional Chinese Medicine (TCM) NIH National Center For Complementary and Alternative Medicine (9/2005 -- 8/2010) Grant # 1 P01 AT002605-01A1 Role: Co-Investigator, (PI: Brian M. Berman, Co-PI: Lixing Lao), 5% effort $1,048,450

Administration Core 10

Under the Center for Arthritis and Traditional Chinese Medicine (TCM) NIH National Center For Complementary and Alternative Medicine (9/2005 -- 8/2010) Grant # 1 P01 AT002605-01A1 Role: Co-Investigator, (PI: Brian M. Berman, Co-PI: Lixing Lao), 5% effort $780,283

International Center for Research on Complementary and Alternative Medicine (ICRC) NIH National Center For Complementary and Alternative Medicine (9/2005 -- 9/2010) Grant # 1 U19 AT003266-01 Role: Co-Investigator, (PI: Brian M. Berman). 10% effort $3,736,925

Project 1: Effects of Electroacupuncture on Visceral Sensation in a Rat Model with Visceral Hyperalgesia Under the International Center for Research on Complementary and Alternative Medicine (ICRC) NIH National Center For Complementary and Alternative Medicine (9/2005 -- 9/2010) Grant # 1 U19 AT003266-01 $417,921 Role: Co-Investigator, (PI: Brian M. Berman). 5% effort

Project 2: Chinese Herbal Formula for the Treatment of Functional Bowel Disorders: In Vitro and In Vivo Evaluation of Safety and Biological Potentials. Under the International Center for Research on Complementary and Alternative Medicine (ICRC) NIH National Center For Complementary and Alternative Medicine (9/2005 -- 9/2010) Grant # 1 U19 AT003266-01 $510,262 Role: Co-Investigator, (PI: Brian M. Berman). 5% effort

Effects of acupuncture on chemotherapy-induced pain NIH National Center For Complementary and Alternative Medicine (2/1/08 – 1/31/11) Grant # R21 AT004113-01 Role: Co-Investigator, (PI: Ruixin Zhang) 5% effort $275,000

Effects of acupuncture on pain-induced affective response NIH National Center For Complementary and Alternative Medicine (12/09 – 11/11) Grant # 1R21AT005474-01 Role: Co-Investigator, (PI: Ruixin Zhang) 5% effort $275,000

Effects of Ginseng CMC's on HIV-related Pain Unhwa Bio Corporation (Private research grant) (1/1/2012-12/31/2012) $206,804 Role: PI, 30%

Cochrane Collaboration CAM Field – Resource for Research NIH National Center For Complementary and Alternative Medicine (5/1/2003 – 04/30/2012) $2,100,322 Grant # 2 R24 AT001293-02, Role: Co-Investigator, (PI: Brian Berman) 5% effort

Auricular Acupuncture for Spinal Cord Injury Related Neuropathic Pain Paralyzed Veterans of America, PVA Research Foundation (06/01/2012-03/31/2014) Grant #2806 Role: Principal Investigator, 12% effort $75,000 11

The mechanism of a Chinese herbal formula on cancer pain NIH FOGARTY INTERNATIONAL CENTER (07/01/2010 – 06/30/2014) Grant # 1R03TW008375-01A1 Role: Principal Investigator, 10% effort (No salary requested) $173,360

P UBLICATIONS

Peer-reviewed Journal Articles 1 ) Franklin R.B., Lao L., Costello L.C. Evidence for two aspartate transport systems in prostate epithelial cells. The Prostate 1990:16(2):137-45. (SCI, IF=3.87) 2) Costello L.C., L ao L., Franklin R. Citrate modulation of high-affinity aspartate transport in prostate epithelial cells. Cell Mol Biol (Noisy-le-grand). 1993 Jul;39(5):515-24. Erratum in: Cell Mol Biol (Noisy-le-grand) 1993 Sep;39(6):701 3) Lao L., Franklin, R.B., Costello, L.C. A high-affinity L-aspartate transporter in prostate epithelial cells that is regulated by Testosterone. The Prostate 1993:22:53-63 (SCI, IF=3.87) 4) Lao L., Bergman, S., Anderson, R., Langenberg, P., Wong, R.H., and Berman, B. The effect of acupuncture on post-operative oral surgery pain: A pilot study. Acupuncture in Medicine 1994:12(1): 13-17 (SCI, IF=2.156) 5) Berman, B., Singh, B.K., Lao, L., Singh, B., Ferentz, K., Hartnoll, S. Primary care physicians’ attitudes towards complementary medicine. J. American Board of Family Physicians 1995:8(5): 361-366 (SCI, IF=0.51) 6) Berman, B., Lao, L., Greene, M., Anderson, R., Wong, R., Langenberg, P., Hochberg, M. Efficacy of traditional Chinese acupuncture in the treatment of symptomatic knee osteoarthritis: A pilot study. Osteoarthritis and Cartilage 1995:3:139-142 (SCI, IF=4.742) 7) Lao, L., Berg man, S., Langenberg, P., Wong, R.L., Berman, B.M. Efficacy of Chinese acupuncture on postoperative oral surgery pain. Oral Surgery, Oral Medicine, Oral Pathology 1995:79(4): 423-428 (SCI, IF=1.690) 8) Lao, L., Wong, R.H., Berman, B., Wynn, R.L. Electroacupuncture reduces morphine-induced emesis in ferrets. J. Alternative and Complementary Medicine, 1995:1(3): 257-261 (SCI, IF=1.622) 9) Lao, L. Acupuncture techniques and devices. J. Alternative and Complementary Medicine. 1996:2(1): 23-25 (SCI, IF=1.622) 10) Lao, L. Safety issues in acupuncture. J. Alternative and Complementary Medicine. 1996:2(1): 27-31 (SCI, IF=1.622) 11) Wong, R.H., Lao, L.#, Berman, B.M., Carter, A., Wynn, R.L. Biphasic emetic response of cyclophosphamide in the ferret. Pharmacology and Biochemistry Behavior. 1997: 58(1): 179-182 (SCI, IF=2.748) 12) Tulder, M.W. van, Cherkin, D.C., Berman, B., Lao, L., Koes, B.W. The effectiveness of acupuncture in the treatment of low back pain. SPINE. 1999: 24(11): 1113-23 (SCI, IF=2.499) 13) Tulder, M.W. van, Cherkin, D.C., Berman, B., L ao, L., Koes, B .W. The effectiveness of acupuncture in the treatment of low back pain. IN The Cochrane Collaboration Library, Issue 2, 1999. Oxford: Update Software (SCI, IF=6.124) 14) Lao, L., Bergman, S., Hamilton, G., Langenberg, P., Berman, B. Evaluation of acupuncture for pain control after oral surgery. JAMA Archives of Otolaryngology: Head and Neck Surgery. 1999: 125(5): 567-572 15) Berman, B., Singh, B., Lao, L., Hochberg, M., Langenberg, P., Li, H., Hadhazy, V. A randomized trial of acupuncture as an adjunctive therapy in osteoarthritis of the knee. British Journal of Rheumatology 1999: 38:346-354 12

16) Lao, L., Zhang, G.,Wei, F., Berman, B. M., Ren, K. Effect of electroacupuncture on hyperalgesia and Fos protein expression in rats with persistent inflammation – a new animal model. Clinical Acupuncture and Oriental Medicine. 1999/2000: 1(2): 112-114 17) Ezzo, J. , Berman, B., Hadhazy, V.A., Jadad, A.R., L ao, L., Singh, B.B. Is acupuncture effective for the treatment of chronic pain? A systematic review. Pain. 2000: 86 (3): 217-225 (SCI, IF=5.445) 18) Ezzo, J, Hadhazy, V.A., Birch S., Lao, L., Kaplan G., Hochberg M., Berman, B. Acupuncture for osteoarthritis of the knee -- A systematic review. Arthritis & Rheumatism. 2001: 44(4): 819-825 (SCI, IF=6.918) 19) Lao, L., Zhang, G., Wei, F., Berman, B. M., Ren, K. Electro-acupuncture attenuates behavioral hyperalgesia and selectively reduces spinal Fos protein expression in rats with persistent inflammation. Journal of Pain. 2001: 2(2): 111-117 (SCI, IF=4.519) 20) Singh, B.B., Berman, B.M., Hadhazy, V., Bareta, J., Lao, L., Zarow, F.M., Hochberg, M. Clinical decisions in the use of acupuncture as an adjunctive therapy for osteoarthritis of the knee. Alternative Therapies. 2001:7(4): 58-65 (SCI, IF=1.247) 21) Stuerzlinger, V., Wang, J., Lao, L. Is Chinese Herbal Medicine Safe?—A review of recent case reports. Akupunktur. 2001: 2: 90-95 (In Germany, English Abstract) 22) Sherman, K., Lao, L., MacPerson, H., Lewith, G., Hopwood, V., Kawakita K. Matching acupuncture c linical st udy designs to research questions. Clinical Acupuncture and Oriental Medicine 2002: 3:12-15 23) MacPerson, H., Sherman, K., Hammerschlag, R., Birch S., Lao, L., Zaslawski C. The clinical evaluation of traditional East Asian systems of medicine. Clinical Acupuncture and Oriental Medicine. 2002: 3:16-19 24) Lao, L., Sherman, K., Bovey, M. The role of acupuncture schools and individual practitioners in acupuncture research. Clinical Acupuncture and Oriental Medicine. 2002: 3:32-38 25) Zhang, G., Bausell, B., Lao, L., Handwerger, B., Berman, B. Assess ing the consistency of TCM diagnosis Alternative Therapies. 2003: 9(1): 66-71 (SCI, IF=1.247) 26) Lao, L., Hamilton, G., Fu, J., Berman, B. Is acupuncture safe? A systematic review of case reports Alternative Therapies. 2003: 9(1): 72-83 (SCI, IF=1.247) 27) Lao, L., Zhang, G., Wong, R., Carter, A., Wynn, R. Berman, B. The effect of electroacupuncture as an adjunct on cyclosphosphamide-induced emesis in ferrets Pharmacology Biochemistry and Behavior. 2003: 74(3): 691-699 (SCI, IF=2.748) 28) Meng, C.F., Wang, D., Ngeow, J., Lao, L., Peterson, M., Paget, S. Acupuncture for chronic low back pain in older patients: a r andomized, controlled trial. Rheumatology (Oxford). 2003 Dec;42(12):1508-17 (SCI, IF=4.818) 29) Wang, H., Wang, Q., Srivastava, R.K., Gong, S., Lao, L., Fondell, J.D., and Wang, J. Effects of total glycosides from baishouwu, on human breast and prostate cancer cell proliferation. Alternative Therapies. 2003: 9(5):62-66 (SCI, IF=1.247) 30) Zhang, R-X, Lao, L., Qiao, J.T. and Ruda, M.A. Strain differences in pain sensitivity and expression of preprodynorphin mRNA in rats following peripheral inflammation. Neurosci. Lett., 2003: 353: 213-216 (SCI, IF=2.18) 31) Lao, L., Ezzo, J. Designing acupuncture trials: one size does not fit all, Clinical Acupuncture & Oriental Medicine. 2003: 3(4): 218 – 221 32) Z hang, G., Bausell, B., Lao, L., Lee, WL, Handwerger, B., Berman, B. The variability of TCM pattern diagnosis and herbal prescription on rheumatoid arthritis patients. Alternative Therapies. 2004: 10(1): 58-63 (SCI, IF=1.247) 33) Lao, L., Zhang, R-X, Zhang, G., Wang, X-Y., Berman, B. M., Ren, K. A parametric study of electroacupuncture on persistent hyperalgesia and Fos protein expression in rats Brain Res. 2004:1020(1-2):18-29 (SCI, IF=2.746)

34) Zhang, R-X,, Lao, L., Qiao, J.T. and Ruda, M.A. Effects of aging on hyperalgesia and spinal dynorphin expression in rats with peripheral inflammation. Brain Res. 2004: 999:135-141(SCI, IF=2.746) 35) Zhang, R-X., Lao, L., Qiao, J.T., Malsnee, K. and Ruda, M.A. Endogenous and exogenous glucocorticoid suppresses up-regulation of preprodynorphin mRNA and hyperalgesia in rats with peripheral inflammation Neurosci. Lett., 2004; 359: 85-88 (SCI, IF=2.18) 36) Zhang, R-X., Lao, L., Wang, X., Ren, K., Berman, B. M. Electroacupuncture Combined with Indomethacin Enhances Anti-Hyperalgesia in Inflammatory Rats. Pharmacology and Biochemistry Behavior. 2004:78:793-797 (SCI, IF=2.748) 37) Zhang, R-X,, Lao, L., Wang, L., Liu, B., Wang, X., Ren, K., Berman, B. M. Involvement of Opioid Receptors in Electroacupuncture-Produced Antihyperalgesia in Rats with Peripheral Inflammation. Brain Res. 2004:1020(1-2):12-17 (SCI, IF=2.746) 38) Sung, J.Y., Leung, W.K., Ching, J.Y.L., Lao, L., Zhang, G., Wu, J.C.Y., Liang, S.M., Xie, H., Ho, Y.P., Chan, L.S., Berman, B., Chan, F.K.L. Agreements among traditional Chinese medicine practitioners in the diagnosis and treatment of irritable bowel syndrome. Alimentary Pharmacology & Therapeutics 2004:20:1205-1210 (SCI, IF=7.286) 39) Seem, G.W., Cassidy, C., Langevin, H., Lao, L., Seem, M. Getting to the points: a forum for master practitioners, researchers, and educators. Clinical Acupuncture and Oriental Medicine. 2004: 4:148-163 40) Berman, B., Lao, L., Langenberg, P., Lee, WL, Gilpin AMK, Hochberg, M. Effectiveness of Acupuncture as Adjunctive Therapy in Osteoarthritis of the Knee: A Randomized, Controlled Trial. Ann Intern Med. 2004;141:901-910 (SCI, IF=17.135) 41) Furlan, A., Tulder, M., Cherkin, D., Tsukayama, H., Lao, L., Koes, B., Berman, B. Acupuncture and dry-needling for low back pain. Cochrane Database Syst Rev. 2005 Jan 25;(1):CD001351 (SCI, IF=6.124) 42) Bausell, R.B., Lao, L., Bergman, S., Lee, W.L., Berman, B. Is Acupuncture Analgesia an Expectancy Effect? Preliminary Evidence Based upon Participants' Perceived Assignments in Two Placebo Controlled Trials. Evaluation & The Health Professions 2005 (Mar);28(1):9-26 (SCI, IF=1.604) 43) Zhang, R-X., Lao, L., Wang, X., Fan, A., Wang, L. Zhang, G., Ren, K., Berman, B. M. Electroacupuncture attenuates inflammation in a rat model. J Altern Complement Med. 2005 Feb;11(1):135-42 (SCI, IF=1.622) 44) Furlan, A.D., Tulder, M., Cherkin, D., Tsukayama, H., Lao, L., Koes, B., Berman, B. Acupuncture and dry-needling for low back pain: an up dated s ystematic review within the framework of the Cochrane Collaboration. Spine. 2005 Apr 15;30(8):944-63 (SCI, IF=2.499) 45) Fan, A.Y., Lao, L., Zhang, R-X., Wang, L-B., Lee, D. Y-W., Ma, Z-Z., Zhang, W-Y., Berman B. Effects of an Acetone Extract of Boswellia carterii Birdw. (Burseraceae) Gum Resin on Rats with Persistent Inflammation. Journal of Alternative and Complementary Medicine 2005 Apr;11(2):323-31 (SCI, IF=1.622) 46) Zhang, R.-X., Wang, L., Wang, X., Ren, K., Berman, B.M., Lao, L. Electroacupuncture combined with mk-801 prolongs anti-hyperalgesia in rats w ith perip heral inflammation. Pharmacology, Biochemistry and Behavior, 2005:81:146-151 (SCI, IF=2.748) 47) Zhang, R.-X., Liu, B., Lao, L., Qiao, J.T., Ruda, M.A. Spinal preprodynorphin mRNA expression in neonatal rats following peripheral inflammation. Brain Res., 2005:1038:238-242 (SCI, IF=2.746) 48) Liu, B., Zhang, R.-X., Wang, L., Ren, K., Qiao, J.T., Berman, B. M., Lao, L. Effects of pertussis toxin on electroacupuncture-produced anti-hyperalgesia in inflamed Rats. Brain Res., 2005:1044:87-92 (SCI, IF=2.746)

49) Zhang, R.-X., Wang, L., Liu, B., Qiao, J.T., Ren, K., Berman, B.M., Lao, L. Mu opioid receptor-containing neurons mediate electroacupuncture-produced anti-hyperalgesia in rats with hind paw inflammation. Brain Res., 2005: 1048(1-2):235-40 (SCI, IF=2.746) 50) Zhang, R.-X., Qiao, J.T., Wang, L., Liu, B., Ren, K., Berman, B.M., Lao, L. Electroacupuncture Suppresses Spinal Expression of Neurokinin-1 Receptors Induced by Persistent Inflammation in Rats. Neuroscience Letters 2005:384(3):339-43 (SCI, IF=2.18) 51) Fan, A.Y., Lao, L., Zhang, R-X., Zhou, A.N., Wang, L-B., Moudgil, K.D., Lee, D. Y-W., Ma, Z-Z., Zhang, W-Y., Berman, B. Effects of an acetone extract of Boswellia carterii Birdw. (Burseraceae) gum resin on adjuvant-induced arthritis in lewis rats. Journal of Ethnopharmacology. 2005: 101(1-3): 104-109 (SCI, IF=2.981) 52) Zhang, G.G., Lee, W., Bausell, B., Lao, L., Handwerger, B., Berman, B. Variability in the traditional Chinese Medicine (TCM) diagnoses and herba l pre scriptions provided by three TCM practitioners for 40 patients with rheumatoid arthritis. Journal of Alternative and Complementary Medicine. 2005:11(3):415-421 (SCI, IF=1.622) 53) Zhang GG, Yu C, Lee W, Lao L, Ren K, Berman BM. Involvement of peripheral opioid mechanisms in electroacupuncture analgesia. Explore (NY). 2005 Sep;1(5):365-71. (SCI, IF=1.363) 54) Ezzo, J.M., Vickers, A.J., Richardson, M.A., Allen, C., Dibble, S.L., Issell, B.F., Lao, L., Pearl, M., Ramirez, G., Roscoe, J.A., Shen, J., Shivnan, J.C., Streitberger, K., Treish, I., Zhan g, G. Acupuncture-Point Stimulation for Chemotherapy-Induced Nausea and Vomiting. Journal of Clinical Oncology. 2005:23(28):7188-98 (SCI, IF=24.008) 55) Zhang, R.-X., Liu, B., Wang, L., Ren, K., Qiao, J.T., Berman, B.M., Lao, L. Spinal glial activation in a new rat model of bone cancer pain produced by prostate cancer cell inoculation of the tibia. Pain. 2005: 118(1-2): 125-136 (SCI, IF=5.445) 56) Zhao, B., Wang, X ., Lin, Z., Liu, R., Lao, L. A Novel Sham Moxibustion Device: A Randomized, Placebo-controlle d Trial. Compleme ntary Therapies in Medicine. 2006:14:53-60 (SCI, IF=2.013)

57) Shen, X., Ding, G., W ei, J., Z hao, L., Zhou, Y., D eng, H., Lao, L. An Infrared Radiation Study of the Biophysical Characteristics of Traditional Moxibustion. Complementary Therapies in Medicine, 2006:14(3):213-219 (SCI, IF=2.013) 58) Lao, L., Fan, A.Y., Zhang, R-X., Zhou, A.N., Ma, Z-Z., Lee, D. Y-W., Ren, K., Berman B. Anti-hyperalgesic and anti-inflammatory effects of the modified Chinese herbal formula Huo Luo Xiao Ling Dan (HLXL) in Rats. American Journal of Chinese Medicine. 2006:34(5):833-844 (SCI, IF=3.222) 59) Lim B, Manheimer E, Lao L, Ziea E, Wisniewski J, Liu J, Berman B. Acupuncture for treatment of irritable bowel syndrome. Cochrane Database Syst Rev. 2006 Oct 18;(4):CD005111. (SCI, IF=6.124) 60) Lao L .Acupuncture practice, past and present: is it safe and effective? J Soc Integr Oncol. 2006 Winter; 4(1):13-5. (SCI, IF=1.622) 61) Ezzo JM, Richardson MA, Vickers A, Allen C, Dibble SL, Issell BF, Lao L, Pearl M, Ramirez G, Roscoe J, Shen J, Shivnan JC, Streitberger K, Treish I, Zhang G. A cupun cture-point stimulation for chemotherapy-induced nausea or vomiting. Cochrane Database Syst Rev. 2006 Apr 19;(2):CD002285 (SCI, IF=6.124) 62) Langevin HM, Hammerschlag R, Lao L, Napadow V, Schnyer RN, Sherman KJ. Controversies in acupuncture research: selection of controls and outcome measures in acupuncture clinical trials. J Altern Complement Med. 2006 Dec;12(10):943-53. (SCI, IF=1.622) 63) Manheimer E, Lim B, Lao L, Berman B. Acupuncture for knee osteoarthritis - a randomised trial using a novel sham. Acupunct Med. 2006 Dec;24 Suppl:S7-14 (SCI, IF=2.156) 64) Li A, Lao L, Wang Y, Zhang H, Ren K, Berman B, Zhang R. Interleukin-1ra inhibits Fos expression and hyperalgesia in rats. Neuroreport. 2007:18(5): 495-498 (SCI, IF=1.395) 15

65) Ren TH, Wu J, Yew D, Ziea E, Lao L, Leung WK, Berman B, Hu PJ, Sung JJ. Effects of neonatal maternal separation on neurochemical and sensory response to colonic distension in a rat model of irritable bowel syndrome. Am J Physiol Gastrointest Liver Physiol. 2007 Mar;292(3):G849-56. (SCI, IF=3.468) 66) Manheimer, E., Linde, K, Lao L, Bouter, LM, Berman, BM. Meta-analysis: Acupuncture for osteoarthritis of the knee. Ann Intern Med. 2007:146:868-877. (SCI, IF=17.135) 67) Li A, Zhang, R-X, Wang Y, Zhang, H., Ren, K., Berman, BM, Tan, M, Lao, L. Corticosterone mediates electroacupuncture-produced anti-edema in a rat model of inflammation. BMC Complementary and Alternative Medicine. 2007: 7:27 (SCI, IF=2.288) 68) Zhang R-X, Li A, Liu B, Wang L, Ren K, Qiao J-T, Berman BM, Lao L. Electroacupuncture attenuates bone cancer pain and inhibits spinal interleukin-1β expression in a rat model. Anesthesia & Analgesia. 2007:105(5): 1482-8 (SCI, IF=4.014) 69) Li A, Wang Y, Xin J, Lao L, Ren K, Berman BM, Zhang RX. Electroacupuncture suppresses hyperalgesia and spinal Fos expression by activating the descending inhibitory system. Brain Res. 2007:1186:171-179 (SCI, IF=2.746) 70) Xu L, Lao L, Ge A, Yu S, Li J, Mansky PJ. Chinese herbal medicine for cancer pain. Integrative cancer therapies. 2007 Sep;6(3):208-34. (SCI, IF=1.923) 71) Xu, L., Wei, P., Sun, D., Lao, L. Quality of reporting in 41 randomized controlled clinical trials of Chinese medicine for ca ncer pain. World Journal of Gastroenterology, 2007,15(35): 3764-3769. (SCI, IF=3.36) 72) Zhang, R.-X., Li A, Liu, B., Wang, L., Ren, K., Zhang, H., Berman, B.M., Lao, L. IL-1ra alleviates inflammatory hyperalgesia through preventing phosphorylation of NMDA receptor NR-1 subunit in rats. Pain, 2008, 135:232-239. (SCI, IF=5.445) 73) Zhang R.-X., Li A, Liu B, Wang L, Xin J, Ren K, Qiao J, Berman BM, Lao L. Electroacupuncture attenuates bone cancer-induced hyperalgesia and inhibits spinal preprodynorphin expression in a rat model. European Journal of Pain, 2008 12:870-878. (SCI, IF=3.019) 74) Shen X, Zhao L, Ding G, Tan M, Gao J, Wang L, Lao L. Effect of combined laser acupuncture on knee osteoarthritis: a pilot study. Lasers Med Sci. 2008 Jan 5 [Epub ahead of print] (SCI, IF=2.299) 75) Chan SK, Zhao M, Lao L, Fong H, Che CT. Magnolol and Honokiol Account for the Anti-Spasmodic Effect of Magnolia officinalis in Isolated Guinea Pig Ileum. Planta Medica. 2008; 74: 381–384 (SCI, IF=2.342) 76) Li A, Lao L, Wang Y, Xin J, Ren K, Berman BM, Tan, M, Zhang RX. Electroacupuncture activates corticotrophin-releasing hormone-containing neurons in the paraventricular nucleus of the hypothalammus to alleviate edema in a rat model of inflammation. BMC Complementary and Alternative Medicine, 2008: 8:20 (SCI, IF=2.288) 77) Zhang, G.G., Singh, B., Lee, W., Handwerger, B., Lao, L., Berman, B. Improvement of agreement in TCM diagnosis among TCM practitioners for persons with the conventional diagnosis of rheumatoid arthritis: effect of training. Journal of Alternative and Complementary Medicine. 2008:14(4):381-386 (SCI, IF=1.622) 78) Shen, X., Ding, G., Deng, H., Wei, J., Zhao, L., Zhou, Y., Lao, L. Infrared radiation spectrum of acupuncture point on patients with coronary heart disease. The American Journal of Chinese Medicine, 2008;36(2):211-8. (SCI, IF=3.222) 79) Shen, X., Zhao, L., Ding, G., Gao, J., Ying, J., Cheng, K., Lao, L. Can a carbon dioxide laser substitute for moxibustion? Lasers Med Sci. 2008 Jul 4 [Epub ahead of print] (SCI, IF=2.299) 80) Zhang, R.-X., Liu, B., Li A, Wang, L., Ren, K., Qiao J, Berman, B.M., Lao, L. Interleukin 1beta facilitates bone cancer pain in rats by enhancing NMDA receptor NR-1 subunit phosphorylation. Neuroscience. 2008 134:1533-8. (SCI, IF=3.277) 16

81) Zhang, RX, Fan, AY, Zhou, A.N, Moudgil, KD Ma, ZZ, Lee, DY, Fong, HH. Berman, BM, Lao, L. Extract of the Chinese herbal formula Huo Luo Xiao Ling Dan inhibited adjuvant arthritis in rats. Journal of Ethnopharmacology, 2009; Jan,121:366–371 doi:10 .1016/j.jep.2008.11.018 (SCI, IF=2.981) 82) Shen X, Zhao L, Ding G, Tan M, Gao J, Wang L, Lao L. Effect of combined laser acupuncture on knee osteoarthritis: a pilot study. Lasers Med Sci. 2009 Mar;24(2):129-36. Epub 2008 Jan 5 (SCI, IF=2.299) 83) Li, YX, Wu, F, Xu L, Lao, L. Research progress of music therapy in treatment of tumor. [in Chinese] J Chin Integr Med, [Zhong Xi Yi Jie He Xue Bao]. 2009, May 7(5):468-71 84) Rajaiah, R, Lee, DY, Ma, ZZ, Fan, AY, Lao, L, Fong, HH, Berman, MB, Moudgil, KD. Huo-Luo-Xiao-Ling Dan modulates antigen-directed immune response in adjuvant-induced inflammation. Journal of Ethnopharmacology, 2009, May, 4;123(1):40-4. Epub 2009 Mar 4. PMID: 19429337 (SCI, IF=2.981) 85) Tchantchou F, Lacor PN, Cao Z, Lao L, Hou Y, Cui C, Klein WL, and Luo Y. Stimulation of Neurogenesis and Synaptogenesis by Bilobalide and Quercetin via Common Final Pathway in Hippocampal Neurons. J Alzheimers Dis 2009 Jan 1;18(4):787-98. (SCI, IF=3.731) 86) Yu S, Peng HD, Ju DW, Wei PK, Xu L, Lao L and Li J. Mechanisms of treatment of cancer pain with a topical Chinese herbal formula in rats. Chinese Medical Journal 2009,122(17):2027-2031 (SCI, IF=1.064) 87) Yu,YB, Dosanjh,L, Tan,M, Shim,B, Lao,L, Luo, Y. Cinnamomi cortex in two herbal formulas extends life span in Caenorhabditis elegans via insulin signaling and stress response pathways. PLoS ONE, 2010, 5(2): e9339. doi:10.1371/journal.pone.0009339 (SCI, IF=2.806) 88) Li, A, Zhang, Y; Lao, L; Xin, J; Ren, K; Berman, BM; Zhang, RX. Serotonin receptor 2A/C is involved in electroacupuncture inhibition of pain in an osteoarthritis rat model. Evidence-based Complementary and Alternative Medicine (eCAM), 2010; doi: 10.1093/ecam/neq016 (SCI, IF=4.774) 89) Manheimer E, Cheng K, Linde K, Lao L, Yoo J, Wieland S, van der Windt DAWM, Berman BM, Bouter LM. Acupuncture for peripheral joint osteoarthritis. Cochrane Database of Systematic Reviews 2010, Issue 1. Art. No.: CD001977. DOI: 10.1002/14651858.CD001977.pub2. (SCI, IF=6.124) 90) Kimbrough E, Lao L, Berman B, Pelletier KR, Talamonti WJ. An integrative medicine intervention in a Ford Motor Company assembly plant. J Occup Environ Med. 2010 Mar;52(3):256-7. (SCI, IF=1.861) 91) Tjong YW, Ip SP, Lao L, Wu J, Fong HH, Sung JJ, Berman B, Che CT. Neonatal maternal separation elevates thalamic corticotrophin releasing factor type 1 receptor expression response to colonic distension in rat. Neuro Endocrinol Lett. 2010 Apr 29;31(2):215-220. [Epub ahead of print] (SCI, IF=0.918) 92) Fan, A.Y., Lao, L., Zhang, R-X., Zhou, A.N., Berman, B. Preclinical safety evaluation of the aqueous acetone extract of Chinese herbal formula Modified Huo Luo Xiao Ling Dan J Chin Integr Med, [Zhong Xi Yi Jie He Xue Bao]. 2010 May;8(5):438-447. (SCI, IF=1.116) 93) Peng, H, Peng HD, Xu L, Lao, LX Efficacy of acupuncture in treatment of cancer pain: a systematic review. J Chin Integr Med, [Zhong Xi Yi Jie He Xue Bao.] 2010 Jun;8(6):501-9. [Chinese] PMID: 20550871 94) Zhao L, Shen X, Cheng K, Deng H, Ding G, Tan M, Lao L. Validating a nonacupoint sham control for laser treatment of knee osteoarthritis. Photomed Laser Surg. 2010 Jun;28(3):351-6. PMID: 19860569 [PubMed - indexed for MEDLINE] (SCI, IF=1.68) 95) Wu JC, Ziea ET, Lao L, Lam EF, Chan CS, Liang AY, Chu SL, Yew DT, Berman BM, Sung JJ. Effect of electroacupuncture on visceral hyperalgesia, serotonin and fos expression in an animal model of irritable bowel syndrome. J Neurogastroenterol Motil. 2010 Jul;16(3):306-14. Epub 2010 Jul 26.PMID: 20680170 [PubMed - in process] (SCI, IF=2.457) 17

96) Langevin HM, Wayne PM, MacPherson H, Schnyer R, Milley RM, Napadow V, Lao L, Park J, Harris RE, Cohen M, Sherman KJ, Haramati A, Hammerschlag R. Paradoxes in Acupuncture Research: Strategies for Moving Forward. Evidence-Based Complementary and Alternative Medicine, vol. 2011, Article ID 180805, 11 pages, 2011. doi:10.1155/2011/180805 (SCI, IF=4.774) 97) Yang YH, Rajaiah R, Lee D, Ma Z, Yu H, Fong, HH, Lao, L, Berman, BM, Moudgil, KD. Suppression of ongoing experimental arthritis by a Chinese herbal formula (Huo-luo-xiao-ling dan) involves changes in antigen-induced immunological and biochemical mediators of inflammation. Evidence-Based Complementary and Alternative Medicine. 2011;2011:642027. Epub 2010 Oct 19. PMID: 20981317 (SCI, IF=4.774) 98) Hui KK, Sporko TN, Vangel MG, Li M, Fang J, Lao L.Perception of Deqi by Chinese and American acupuncturists: a pilot survey. Chine se Medicine 2011 Jan 20;6(1):2. PMID: 21251312 (SCI, IF=1.508) 99) Wang JY, Xu L, Zhang RX, Lao L. Traditional Chinese Medicine for Cancer Pain. Zhong Xi Yi Jie He Xue Bao. 2011 Feb;9(2):129-134. [Chinese]. PMID: 21288445 100) Lao L, Huang Y, Feng C, Berman BM, Tan M. Evaluating Traditional Chinese Medicine Using Modern Clinical Trial Design and Statistical Methodology: Application to a Randomized Controlled Acupuncture Trial Statistics in Medicine. 2011 Feb 23. doi: 10.1002/sim.4003. [Epub ahead of print], PMID: 2 1344469 (SCI, IF=1.8 77) 101) Shuai P, Zhou XH, Lao L, Li X. Issues of design and statistical analysis in controlled clinical acupuncture trials: An analysis of English-language reports from Western journals. Stat Med. 2011 Feb 22. doi: 10.1002/sim.4034. [Epub ahead of print] 102) Bao T, Zhang R, Badros A, Lao L. Acupuncture Treatment for Bortezomib-Induced Peripheral Neuropathy: A Case Report," Pain Research and Treatment, Vol. 2011, Article ID 920807, 4 pages, 2011. doi:10.1155/2011/920807. 103) Tjong YW, Ip SP, Lao L, Wu J, Fong HH, Sung JJ, Berman B, Che CT. Role of neuronal nitric oxide synthase in colonic distension-induced hyperalgesia in distal colon of neonatal maternal separated male rats. Neurogastroenterol Motil. 2011 Mar 16. doi: 10.1111/j.1365-2982.2011.01697.x. [Epub ahead of print] PMID: 21410601 (SCI, IF=3.671) 104) Zhang Y, Li A, Xin J, Lao L, Ren K, Berman BM, Tan M, Zhang RX. Involvement of spinal serotonin receptors in electroacupuncture anti-hyperalgesia in an inflammatory pain rat model. Neurochemical Research; 2011 DOI: 10.1007/s11064-011-0495-1(SCI, IF=2.581) 105) Tjong YW, Ip SP, Lao L, Fong HH, Sung JJ, Berman B, Che CT. Analgesic effect of Coptis chinensis rhizomes (Cop tidis Rhizoma) extract on rat model of irritable bowel syndrome. Journal of Ethnopharmacology; 2011 (135): 754-761(SCI, IF=2.981) 106) Witt CM, Lao L, Macpherson H. Evidence on acupuncture safety needs to be based on large-scale prospective surveys, not single case reports. Pain. 2011 May 5. [Epub ahead of print] (SCI, IF=5.445) 107) Manheimer E, Stafford K, Liu J, Tierney J, Lao L, Berman B, Bouter L. Effects of adjuvant acupuncture on pregnancy rates among women undergoing in vitro fertilization: systematic review and meta-analysis. CRD Register 2011: CRD42011001309. 108) Li A, Zhang Y, Lao L, Xin J, Ren K, Berman BM, Zhang RX. Serotonin Receptor 2A/C Is Involved in Electroacupuncture Inhibition of Pain in an Osteoarthritis Rat Model. eCAM. 2011:619650. Epub 2011 Jan 9. (SCI, IF=4.774) 109) Zhang Y, Li A, Lao L, Xin J, Ren K, Berman BM, Zhang RX. Rostral ventromedial medulla μ, but not κ, opioid receptors are involved in electroacupuncture anti-hyperalgesia in an inflammatory pain rat model. Brain Res. 2011 Jun 13;1395:38-45. Epub 2011 Apr 28. PMID: 21565329 [PubMed - in process] (SCI, IF=2.623)

110) Zhang Y, Meng X, Li A, Xin J, Berman BM, Lao L, Tan M, Ren K, Zhang RX. Acupuncture alleviates the affective dimenstion of pain in a rat model of inflammatory hyperalgesia. Neurochem Res. 2011 Jun 22. [Epub ahead of print] PMID: 21695393 (SCI, IF=2.24) 111) Meng X, Xu S, Lao L. Clinical acupuncture research in the west. Front Med. 2011 June; 5(2): 134-40. Epub 2011 June 22. PMID: 21695617 112) Zhang Y, Meng X, Li A, Xin J, Berman BM, Lao L, Tan M, Ren K, Zhang RX. Electroacupuncture alleviates affective pain in an inflammatory pain rat model. Eur J Pain. 2011 Aug 3. [Epub ahead of print] (SCI, IF=3.819) 113) Yi M, Zhang H, Lao L, Xing GG, Wan Y. Anterior cingulate cortex is crucial for contra- but not ipsi-lateral electro-acupuncture in the formalin-induced inflammatory pain model of rats. Mol Pain. 2011 Aug 22;7(1):61. [Epub ahead of print] (SCI, IF=4.148) 114) Meng X, Zhang Y, Li A, Xin J, Lao L, Ren K, Berman BM, Tan M, Zhang RX. The effects of opioid receptor antagonists on electroacupuncture-produced anti-allodynia/hyperalgesia in rats with paclitaxel-evoked peripheral neuropathy. Brain Res. 2011 Aug 7:58-65. [Epub ahead of print] (SCI, IF=2.623)

115) Meng XZ, Wu F, Wei PK, X iu LJ,Shi J,Pang B,Sun DZ, Q in ZF, Huang Y, a nd Lao L. A Chinese Herbal Formula to Improve General Psychological Status in Post-Traumatic Stress Disorder: A randomized placebo-controlled trial on Sichuan earthquake survivors. eCAM. Volume 2012 (2012), Article ID 691258, 11 pages doi:10.1155/2012/691258 (SCI, IF=4.7 74) 116) Yang JM, Xian YF, Ip PS, Wu JC, Lao L, Fong HH, Sung JJ, Berman B, Yeung JH, Che CT. Schisandra chinensis reverses visceral hypersensitivity in a neonatal-maternal separated rat model. Phytomedicine. 2012 Jan 7. [Epub ahead of print] PMID: 22230486 (SCI, IF=2.662) 117) Yang Z, Grinchuk Vi, Ip SP, Che CT, Fong HHS, Lao L, Wu JC, Sung JJ, Berman B, Shea-Donohue T, Zhao A. Anti-inflammatory Activities of a Chinese Herbal Formula IBS-20 in vitro and in vivo. Evidence-based Complementary and Alternative Medicine, Volume 2012 (2012), Article ID 49 1496, 12 pages doi:10.1155/2012/491496 (SCI, IF=4.774) 118) Zhang Y, Lao L, Chen, H and Ceballosh R. Acupuncture use among American adults: what acupuncture practitioners can learn from National Health Interview Survey 2007 Evidence-based Complementary and Alternative Medicine, Volume 2012 (2012), Article ID 710750, 8 pages doi:10.1155/2012/710750 (SCI, IF=4.774) 119) Zhang R, Lao L. A new rat model of bone cancer pain. Methods Mol Biol. 2012;851:261-73. PMID: 22351098 (SCI, IF=1.29) 120) Nanjundaiah S, Lee D, Ma Z, Fong HH, Lao L, Berman B, Moudgil KD. Modified Huo-Luo-Xiao-Ling Dan (HLXL) Suppresses Ad juvant Arthritis by Inhibiting Chemokines and Matrix-Degrading EnzymesModified Huo-Luo-Xiao-Ling Dan (HLXL) Suppresses Adjuvant Arthritis by Inhibiting Chemokines and Matrix-Degrading Enzymes. Evidence-Based Complementary and Alternative Medicine, Volume 2012 (2012), Article ID 589256, 8 pages doi:10.1155/2012/589256 (SCI, IF=4.774) 121) Xu SF and Lao L. From Basic Science Studies to Clinical Trials: What Recent Acupuncture Research Tells Us. Medical Acupuncture, Vol. 24, No. 1, March 2012: 10-14. 122) Liu T, Lao L. Letter to Editor: Tai chi for patients with Parkinson's disease. N Engl J Med. 2012 May 3;366(18):1737 (SCI, IF=72.406) 123) Xu SF, Li S, Shen X, Meng X, Lao L. Effects of electroacupuncture on depression in a rat model. Acupunct Electrother Res. 2011;36(3-4):259-73. PMID: 22443027 124) Zhuang LX, Xu SF, D’Adamo, Jia C, He J, Han DX, Lao LX. An effectiveness study comparing acupuncture, physiotherapy and their combination in post-stroke rehabilitation -A multi-centered randomized controlled clinical trial. Alternative Therapies In Health And Medicine; 2012, 18(3):8-13. (SCI, IF=1.215)

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137) Cheng CW, Fu SF, Zhou QH, Wu TX, Shang HC, Tang XD, Liu ZS, Liu J, Lin ZX, Lao L, Lü AP, Zhang BL, Liu BY, Bian ZX. Extending the CONSORT Statement to moxibustion. J Integr Med. 2013 Jan;11(1):54-63. doi: 10.3736/jintegrmed2013009. 138) Xianz e Meng; Yu Zhang; Lixing Lao; Rikka Saito; Aihui Li; Cristina M Backman; Brian M Berman; Ke Ren; Pin-Kang Wei; Ruixin Zhang. Spinal interleukin-17 promotes thermal hyperalgesia and NMDA NR1 phosphorylation in an inflammatory pain rat model. Pain. 2013 Feb;154(2):294-305. doi: 10.1016/j.pain.2012.10.022. Epub 2012 Nov 5. (SCI, IF=5.777) 139) Bruehl S, Apkarian AV, Ballantyne JC, Berger A, Borsook D, Chen WG, Farrar JT, Haythornthwaite JA, Horn SD, Iadarola MJ, Inturrisi CE, Lao L, Mackey S, Mao J, Sawczuk A, Uhl GR, Witter J, Woolf CJ, Zubieta JK, Lin Y. Personalized medicine and opioid analgesic prescribing for chronic pain: opportunities and challenges. J Pain. 2013 Feb;14(2):103-13. doi: 10.1016/j.jpain.2012.10.016. (SCI, IF=4.851) 140) Xu SF, Wang LZ, Cooper, E, Zhang M, Manheimer E, Berman B, Shen XY, Lao L., Adverse Events of Acupuncture: A Systematic Review of Case Reports. Evidence-based Complementary and Alternative Medicine; Volume 2013 2013:581203. doi: 10.1155/2013/581203. Epub 2013 Mar 20. (SCI, IF=4.774) 141) Haolin Zhang, Xiaolong Chen, Chan Zhang, Ruixin Zhang, Lixing Lao, You Wan and M. Yi. Comparison of restrained and unrestrained rat models of electro-acupuncture in rats Evidence-based Complementary and Alternative Medicine; Volume 2013, Article ID 404956, 5 pages. doi.org/10.1155/2013/404956), (SCI, IF=4.774) 142) Lijun Bai, Fangyuan Cui, Yihuai Zou, and Lixing Lao. Acupuncture De Qi in Stable Somatosensory Stroke Patients: Relations with Effective Brain Network for Motor Recovery. Evid Based Complement Alternat Med. 2013;2013:197238. doi: 10.1155/2013/197238. Epub 2013 Jun 2. (SCI, IF= 4.774) 143) Lijun Bai and Lixing Lao. Neurobiological foundations of acupuncture: the relevance and future prospec t based on neuroimaging evidence. Evid Based Complement Alternat Med. 2013;2013:812568. doi: 10.1155/2013/812568. Epub 2013 May 14. (SCI, IF= 4.774) 144) Yingxue Cui, Baixiao Zhao, Yuhai Huang, Zhanghuang Chen, Ping Liu, Jian Huang and Lixing Lao. Effects of Moxa (Artemisiae Argyi Folium) Smoke Exposure on Heart Rate and Heart Rate Variability in Healthy Young Adults: A Randomized, Controlled Human Study Evidence-based Complementary and Alternative Medicine; Volume 2013 Article ID 510318, 10 pages. (SCI, IF= 4.774) 145) Huanfang Xu, Yingxue Cui, Ping Liu, Li Han, Baixiao Zhao, Min Yee Lim, Hongzhu Guo and Lixing Lao. Effects of moxa smoke on monoamine neurotransmitters in SAMP8 mice. Evidence-based Complementary and Alternative Medicine; Volume 2013 Article ID 178067, 6 pages. (SCI, IF= 4.774) 146) Liu Z, Liu J, Zhao Y, Cai Y, He L, Xu H, Zhou X, Yan S, Lao L, Liu B. The efficacy and safety study of electro-acupuncture for severe chronic functional constipation: study protocol for a multicenter, randomized, controlled trial. Trials. 2013 Jun 15;14(1):176. doi: 10.1186/1745-6215-14-176. (SCI, IF= 2.117) 147) Eric Manheimer; Danielle van der Windt; Ke Cheng; Kristen Stafford; Jianping Liu; Jayne Tierney; Lixing Lao; Brian M. Berman; Patricia Langenberg; Lex M. Bouter. The effects of acupuncture on rates of clinical pregnancy among women undergoing in vitro fertilization: a systematic review and meta-analysis. Human Reproduction Update 2013; doi: 10.1093/humupd/dmt026. (SCI, IF= 10.165) 148) Bai L, Zhang M, Chen S, Ai L, Xu M, Wang D, Wang F, Liu L, Wang F, Lao L. Characterizing acupuncture de qi in mild cognitive impairment: relations with small-world efficiency of functional brain networks. Evid Based Complement Alternat Med. 2013;2013:304804. doi: 10.1155/2013/304804. Ep u b 2013 Jul 11. (SCI, IF= 4.774)

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252) Yeung WF, Chung KF, Zhang ZJ, Zhang SP, Chan WC, Ng RM, Chan CL, Ho LM, Yu BY, Chau JC, Lau NC, Lao LX. Electroacupuncture for tapering off long-term benzodiazepine use: A randomized controlled trial. J Psychiatr Res. 2019 Feb;109:59-67. doi: 10.1016/j.jpsychires.2018.11.015. Epub 2018 Nov 22. PMID: 30504097. (SCI, IF=3.745) 253) Wei Li, Ping Yin, Lixing Lao*(Co-corresponding author)., and Shifen Xu, “Effectiveness of Acupuncture Used for the Management of Postpartum Depression: A Systematic Review and Meta-Analysis,” BioMed Research International, vol. 2019, Article ID 6597503, 8 pages, 2019. (IF: 2.583) 254) Yin X, Dong B, Liang T, Yin P, Li X, Lin X, Zhou S, Qian X, Lao L*(Co-corresponding author), Xu S. Efficacy and safety of electroacupuncture on treating depression-related insomnia: a study protocol for a multicentre randomised controlled trial. BMJ Open. 2019 Apr 1;9(4):e021484. (SCI,IF=2.369) 255) Li S, Yin P, Yin X, Bogachko A, Liang T, Lao L, Xu S. Effect of acupuncture on insomnia in menopausal women: a study protocol for a randomized controlled trial. Trials. 2019 May 30;20(1):308. doi: 10.1186/s13063-019-3374-8. PMID: 31146772; PMCID: PMC6543678. (SCI, IF=1.883) 256) Zhao Y, Luo D, Ning Z, Rong J, Lao L*(Co-corresponding author). Electro-Acupuncture Ameliorated MPTP-Induced Parkinsonism in Mice via TrkB Neurotrophic Signaling. Front Neurosci. 2019 May 14;13:496. doi: 10.3389/fnins.2019.00496. PMID: 31156376; PMCID: PMC6528026. (SCI, IF= 3.810) 257) Zhao J, Zhu M, Kumar M, Ngo FY, Li Y, Lao L, Rong J. A Pharmacological Appraisal of Neuroprotective and Neurorestorative Flavonoids Against Neurodegenerative Diseases. CNS Neurol Disord Drug Targets. 2019;18(2):103-114. doi: 10.2174/1871527317666181105093834. PMID: 30394219. (SCI, IF= 2.761) 258) Zhao, J., Lao, L., Cui, W., and Rong, J. Potential link between the RagA-mTORp70S6K axis and depre ssive-behaviors during bacterial liposaccharide challenge. Journal of Neuroinflammation. 2019:16:211 (SCI, IF=5.70) 259) Han L, Liu C, Sun W, Yang X, Zhang C, Zhao B, Huang C, Yang J, Wang L, Bai H, Liu J, Lim M, He R, Huang J, Liu P, Ju D, Lao L. Twelve-week study of moxa smoke: occupational exposure in female rats. J Tradit Chin Med. 2019 Apr;39(2):207-212. (SCI, IF= 0.676) 260) Zhang L, Ng TB, Lam JKW, Wang SW, Lao L, Zhang KY, Sze SCW. Research and Development of Proteins and Peptides with Therapeutic Potential from Yam Tubers. Curr Protein Pept Sci. 2019;20(3):277-284. doi: 10.2174/1389203719666180622094356. PMID: 29932033. (SCI, IF= 2.520) 261) Cheng IC, Li RK, Leung GP, Li SL, Kong M, Lao LX, Zhang ZJ, Lin WL, Ng EH, Rong JH, Chen JP, Su J, Zhang KY, Meng W. Application of UPLC-MS/MS to simultaneously detect four bioactive compounds in the tumour-shrinking decoction (FM1523) for uterine fibroids treatment. Phytochem Anal. 2019 Jul;30(4):447-455. doi: 10.1002/pca.2827. Epub 2019 Mar 27. PMID: 30916852. (SCI, IF= 2.772) 262) Yong Ke You Qi Luo Wei Feng Wu Jiao Jiao Zhang Hong Jian Zhu Lixing Lao Hui Y. Lan H- ai Yong Chen Yong- Xian Cheng. P-etchiether A attenu-ates obstru ctive nephropathy by - - suppressing TGF β/Smad3 and NF κB signaling. J Cell Mol Med. 2019;23:5576–5587 (IF= - - 4.499) 263) Yang M, Sun M, Du T, Long H, Chen J, Liang F, Lao L. The efficacy of acupuncture for stable angina pectoris: A systematic review and meta-analysis. Eur J Prev Cardiol. 2019 Sep 17:2047487319876761. doi: 10.1177/2047487319876761. Epub ahead of print. PMID: 31529993. (SCI, IF= 3.606) 264) Li Y, Yang M, Wu F, Cheng K, Chen H, Shen X, Lao L. Mechanism of electroacupuncture on inflammatory pain: neural-immune-endocrine inte ractions. J Tradit Chin Med. 2019 Oct;39(5):740-749. 30

265) Chen Y, Zhang W, Wu H, Lao L, Xu J, Xu S. Combination of acupuncture and Chinese herbal formula for elderly adults with mild cognitive impairment: protocol for a randomized controlled trial. Trials. 2019 Dec;20(1):117. (IF: 2.067) 266) Guo MH, Zhao L, Wu F, Du J, Ding CH, Ge JH, Tan MT, Lao LX, Shen XY, Cheng K. CO2 Laser Moxibustion for Knee Osteoarthritis: Study Protocol for A Multicenter, Double-blind, Randomized Controlled Trial. Chin J Integr Med. 2020 Jan 23. (SCI,IF=1.445) 267) Li Y, Wu F, Wei J, Lao L, Shen X. The Effects of Laser Moxibustion on Knee Osteoarthritis Pain in Rats. Photobiomodul Photomed Laser Surg. 2020 Jan;38(1):43-50. doi: 10.1089/photob.2019.4716. Epub 2019 Sep 24. PMID: 31549920; PMCID: PMC6978776. (SCI,IF=1.913) 268) Gao XY, Qiao M, Zhang DW, Ren S, Lao LX, Yang XG, Shen YC, Zheng MC, Lei Y, Chen XW, Wen J. Exploration and practice of micro-video teaching of Characteristic Clinical Technology of Acupuncture and Moxibustion. Zhongguo Zhen Jiu. 2020 Jan 12;40(1):103-5. 269) Li S, Zhang Q, Yin X, Yue H, Zhang W, Lao L, Zhang Z, Wu H, Xu S. Electroacupuncture for postoperative pain after nasal endoscopic surgery: study protocol for a pilot randomized controlled trial. Trials. 2020 Feb 11;21(1):163. (SCI,IF=1.975) 270) Cheung DST, Tiwari A, Yeung WF, Yu DSF, So MKP, Chau PH, Wang XM, Lum TYS, Yuk Fung HYK, Ng BYM, Zhang ZJ, Lao L. Self-Administered Acupressure for Caregivers of Older Family Members: A Randomized Controlled Trial. J Am Geriatr Soc. 2020 Feb 25. (SCI,IF=4.388) 271) Yang M, Du T, Long H, Sun M, Liang F, Lao L. Acupuncture for menstrual migraine: a systematic review. BMJ Support Palliat Care. 2020 Mar 2. (SCI, IF=2.590) 272) Zhang C, Wang N, Tan HY, Guo W, Chen F, Zhong Z, Man K, Tsao SW, Lao L, Feng Y. Direct inhibition of the TLR4/MyD88 pathway by geniposide suppresses HIF-1α-independent VEGF expression and angiogenesis in hepatocellular carcinoma. Br J Pharmacol. 2020 Mar 6. (SCI,IF=6.583) 273) Zhao FY, Fu QQ, Zheng Z, Lao LX, Song HL, Shi Z. Verum- versus Sham-Acupuncture on Alzheimer's Disease (AD) in Animal Models: A Preclinical Systematic Review and Meta-Analysis. Biomed Res Int. 2020 Mar 31;2020:5901573. doi: 10.1155/2020/5901573. PMID: 32337259; PMCID: PMC7150729. 274) Zhang YB, Lam KH, Chen LF, Wan H, Wang GC, Lee KF, Yip CW, Liu KH, Leung PH, Chan HY, Shi YG, Zhao J, Lao LX, Li YL, Zhang YB, Meng W. Chemical constituents from the thorns of Gleditsia sin ensis a nd their cytotoxic activities. J Asian Nat Prod Res. 2020 Apr 15:1-9. (SCI,IF=1.170) 275) Li Y, Wu F, Wei J, Lao L, Shen X. Laser Moxibustion Alleviates Knee Osteoarthritis Pain by Inhibiting Spinal Microglial Activation-Mediated Neuroinflammation in Rats. Photobiomodul Photomed Laser Surg. 2020 Apr;38(4):237-243. (SCI,IF=1.913) 276) Cheung DST, Yeung WF, Suen LK, Chong TC, Ho YS, Yu BY, Chan LY, Chen HY, Lao LX. Self-administered acupressure for knee osteoarthritis in middle-aged and older adults: a pilot randomized controlled trial. Acupunct Med. 2020 Apr;38(2):75-85. (SCI,IF=2.637) 277) Chen HY, Wang C, Zhou M, Chan PY, Yam LL, Lam WL, Leung KP, Li SY, Tsang WY, Ng BFL, Ziea ETC, Yeung WF, Lao LX, Electroacupuncture for post-stroke overactive bladder: a multi-centre pilot randomized controlled trial. Acupuncture in Medicine. 2020 July (SCI, IF=2.129) 278) Yin X, Li W, Wu H, Dong B, Ma J, Li S, Lao L, Xu S. Efficacy of Electroacupuncture on Treating Depression-Related Insomnia: A Randomized Controlled Trial. Nat Sci Sleep. 2020 Jul 21;12:497-508. doi: 10.2147/NSS.S253320. PMID: 32765146; PMCID: PMC7382580. (SCI, IF= 3.230)

279) Zhao L, Cheng K, Wu F, Du J, Chen Y, Tan MT, Lao L, Shen X. Effect of laser moxibustion for knee osteoarthritis: a multi-site double-blind randomized controlled trial. J Rheumatol. 2020 Jul 1:jrheum.200217. doi: 10.3899/jrheum.200217. Epub ahead of print. PMID: 32611673. (SCI, IF= 3.187) 280) Cheung DST, Yeung WF, Chau PH, Lam TC, Yang M, Lai K, Ip CY, Lao L, Lin CC. Patient-centred, self-administered acupressure for Chinese advanced cancer patients experiencing fatigue and co-occurring symptoms: A pilot randomised controlled trial. Eur J Cancer Care (Engl). 2020 Sep 7:e13314. doi: 10.1111/ecc.13314. Epub ahead of print. PMID: 32896014. (SCI, IF= 2.34) 281) Li W, Sun M, Yin X, Lao L, Kuang Z, Xu S. The effect of acupuncture on depression and its correlation with metabolic alterations: A randomized controlled trial. Medicine (Baltimore). 2020 Oct 23;99(43):e22752. doi: 10.1097/MD.0000000000022752. PMID: 33120777; PMCID: PMC7581113. 282) Chen Y, Xiang XY, Chin KHR, Gao J, Wu J, Lao L, Chen H. Acupressure for labor pain management: a systematic review and meta-analysis of randomized controlled trials. Acupunct Med. 2020 Aug 18:964528420946044. doi: 10.1177/0964528420946044. Epub ahead of print. PMID: 32811182. 283) Shao BY, Zhang XT, Vernooij RWM, Lv QY, Hou YY, Bao Q, Lao LX, Liu JP, Zhang Y, Guyatt GH. The effectiveness of Baduanjin exercise for hypertension: a syste matic review and meta-analysis of randomized controlled trials. BMC Complement Med Ther. 2020 Oct 8;20(1):304. doi: 10.1186/s12906-020-03098-w. PMID: 33032580; PMCID: PMC7545896. (SCI, IF= 2.610) 284) Shao B, Hou S, Chan Y, Shao C, Lao L. Remission of new-onset type 2 diabetes mellitus in an adolescent using an integrative medicine approach: A case report. J Integr Med. 2020 Oct 22:S2095-4964(20)30121-7. doi: 10.1016/j.joim.2020.10.005. Epub ahead of print. PMID: 33162376.(SCI, IF= 2.446) 285) Zhao Y, Zhao J, Zhang X, Cheng Y, Luo D, Lee SM, Lao L, Rong J. Botanical Drug Puerarin Promotes Neuronal Survival and Neurite Outgrowth against MPTP/MPP+-Induced Toxicity via Progesterone Receptor Signaling. Oxid Med Cell Longev. 2020 Oct 17;2020:7635291. doi: 10.1155/2020/7635291. PMID: 33123315; PMCID: PMC7586160. (SCI, IF=5.076) 286) Wang X, Yin X, Guo XT, Wang Y, Jin WQ, Mao AJ, Lao L, Zhang ZJ, Zhang J, Xu SF. Effects of the pestle needle therapy, a type of acupoint stimulation, on post-hemorrhoidectomy pain: A randomized controlled trial. J Integr Med. 2020 Nov;18(6):492-498. doi: 10.1016/j.joim.2020.08.001. Epub 2020 Aug 6. PMID: 32798197. 287) Mu J, Furlan AD, Lam WY, Hsu MY, Ning Z, Lao L*(Corresponding author). Acupuncture for chronic nonspecific low back pain. Cochrane Database of Systematic Reviews 2020, Issue 12. Art. No.: CD013814. DOI: 10.1002/14651858.CD013814. (IF: 7.890) 288) Li S, Wang Z, Wu H, Yue H, Yin P, Zhang W, Lao L, Mi Y, Xu S. Electroacupuncture versus Sham Acupuncture for Perimenopausal Insomnia: A Randomized Controlled Clinical Trial. Nat Sci Sleep. 2020;12:1201-1213 https://doi.org/10.2147/NSS.S282315 (IF: 3.230) Non-peer-reviewed Articles, Editorial Tasks, Invited Articles 1) Lao, L., Daniel, K. M., Case Study: Differentiation and treatment: urticaria and herpes zoster. The MAS Journal 1990:2(1): 7-8 2) Lao, L. (Consultant) Acupuncture. IN S. Loeb (Ed.) Handbook of Therapeutic Interventions. Springhouse: Springhouse Corporation, 1994 3) Lao, L. Book Review. Alternative Therapies in Health and Medicine 1996:2(5): 132 4) Lao, L. Commentary. Research in Complementary Medicine. 1997:4:125-132 5) Lao, L. For ward IN Hart, C., Goh, M. Traditional Chinese Medicin e. New York: Dell Publishing, 1997 32

6) Hammerschlag, R., Culliton, P.D., Langevin, H.M., Lao L. A new partnership: the Society for Acupuncture Research and the Journal of Alternative and Complementary Medicine. [Editorial] Journal of Alternative & Complementary Medicine. 2003:9(6):807-8 7) Lao, L. Recommendations for enhancing the quality of traditional Chinese medicine clinical research reporting (in Chinese) J Chin Integr Med, 2004, 2(6):402-406 8) Lao, L., Berman B.M., Evaluating the effects of acupuncture on knee osteoarthritis, a stepwise approach to research—University of Maryland experience. American Journal of Traditional Chinese Medicine, 2005;6(1):5-12 9) Berman, B.M., Cilpin, A.M.K., Lao, L. In Response to Letter to Editor. Ann Intern Med. 2005;142:872-873 10) Berman, BM, Lao, L, Langenberg, P, Lee WL, Cilpin, AMK, Hochberg MC. Letter to Editor Focus on Alternative and Complementary Therapies. 2005;June:10[2]:122 11) Lao, L. Commentary on Sood, et al., Cochrane Systematic Reviews in Acupuncture: Methodological Diversity in Database Searching. Journal of Alternative and Complementary Medicine 2005;11(4):723-724 12) Lao, L., Berman, B.M., Evaluating the effects of acupuncture on knee osteoarthritis, a stepwise approach to research—University of Maryland experience. (in Chinese) J Chin Integr Med, 2005, 3(6):421-5 13) Shen , X, Ding, G.H., Wei, J., Ling, Zhou, W., Zhou, L., Deng, H., Lao, L. The biophysical basis of traditional moxibustion. Journal of Alternative and Complementary Medicine, 2006, 12(2): 224-225 14) Ding, G.H., Shen, X., Deng, H., Wei, J., Zhao, L., Zhou, Y., Lao, L. Infrared radiation spectrums at acupuncture point Nei Guan (PC6) on patients with coronary heart disease. Journal of Alternative and Complementary Medicine, 2006, 12(2): 207 15) Lao, L., Brian Berman. Evaluating the effects of acupuncture on knee osteoarthritis- a stepwise approach to research, University of Maryland experience. The American Acupuncturist - AAAOM’s Official Publication for Practitioners of Oriental Medicine. 2007;40:8-11 16) Lao, L. [Acupuncture clinical studies and evidence-based medicine--an update] Zhen Ci Yan Jiu. 2008 Feb;33(1):53-61. Chinese 17) Lao, L. Current status of acupuncture clinical research-challenges and methodology . The American Acupuncturist - AAAOM’s Official Publication for Practitioners of Oriental Medicine. 2008;44:26-31 18) Napadow V, Ahn A, Longhurst J, Lao L, Stener-Victorin E, Harris R, Langevin HM. The status and future of acupuncture clinical research. J Altern Complement Med. 2008 Sep;14(7):861-9. PMID: 18803495 19) Schnyer R, Lao L, Hammerschlag R, Wayne P, Langevin HM, Napadow V, Harris R, Park J, Milley R, Cohen M, MacPherson H. Society for Acupuncture Research: 2007 conference report: "The status and future of acupuncture research: 10 years post-NIH Consensus Conference". J Altern Complement Med. 2008 Sep;14(7):859-60. PMID: 18803494 20) Lao L, Schy ner RN. Society for Acupunc ture Research 2007 Conference "The Status and Future of Acupuncture Research: 10 Years Post-NIH Consensus Conference", Baltimore, MD. J Altern Complement Med. 2008 Sep;14(7):857. PMID: 18803493 21) Lao L, Berman BM The Center for Integrative Medicine at the University of Maryland: the first complementary and alternative medicine center in a US medical school [in Chinese] J Chin Integr Med, [Zhong Xi Yi Jie He Xue Bao]. 2008 Nov;6(11):1205-9. 22) Zhang D, Yao W, Ding GH, Yang J, Schwarz W, Fei L, Liu F, Shen X, Lao L. A fluid mechanics model of tissue fluid flow in limb connective tissue-a mechanism of acupuncture signal transmission, Journal of Hydrodynamics. 2009, 21(5):675-684

23) Lao, L. Traditional Chinese Medicine, How do you treat osteoarthritis in your practice? -- Clinical Roundup. Alternative and Complementary Therapies. 2009, 15(2): 87; DOI:10.1089/act.2009.15205 24) Lao, L. Promoting Acceptance of Acupuncture and Traditional Chinese Medicine. Interview by Anne Lanctôt and Suzanne Snyder. Altern Ther Health Med. 2010 Nov-Dec;16(6):66-74. PMID: 21280464 25) 周一辰，徐世芬，Lixing Lao. 针灸和中医药在美国的发展概况. 环球中医药，2011；4（1）： 58-61 26) Meng X, Xu S, Lao L. Clinical acupuncture research in the West. Front Med. 2011 Jun;5(2):134-40. Epub 2011 Jun 22. Review.PMID: 21695617 27) Shen XY, Lao L, Zhang Y, Cheng K. Biophysical and clinical research on acupuncture and moxibustio n. Evid Based Complement Alternat Med. 2015;2015:518138. doi: 10.1155/2015/518138. 28) Ning Z, Lao L. Acupuncture for Pain Management in Evidence-based Medicine. J Acupunct Meridian Stud. 2015 Oct;8(5):270-3. doi: 10.1016/j.jams.2015.07.012. Epub 2015 Sep 1. 29) 張曉雨,寧志鵬,陳海勇,勞力行. 針刺治療膝骨性關節炎的臨床試驗結果與對照組設置相關性研究的系統分析[J]. 中國疼痛醫學雜志,2015,(10). 30) Lao L, Ning Z. Integrating traditional Chinese medicine into mainstream healthcare system in Hong Kong, China-A model of integrative medicine in the HKU-SZ Hospital. J Integr Med. 2015 Nov;13(6):353-5. doi: 10.1016/S2095-4964(15)60218-7. 31) 黄飞霞, 陈海勇, 裴霞, 陆怡衡, 周立群, 劳力行, 宋佳, 孙灵芝, 甄雪燕, 赵艳, 郑越. 胡焕章运用“知常达变”治疗脾胃病经验. 河北中医 2017,06(39),805-808+818. DOI:10.3969/j.issn.1002-2619.2017.06.001. 32) 宋佳, 孙灵芝, 甄雪燕, 赵艳, 郑越, 劳力行, 陈海勇, 裴霞, 陆怡衡, 黄飞霞, 周立群. 论外感与内伤的统一性. 新中医 2017,07(49),174-177. DOI:10.13457/j.cnki.jncm.2017.07.061. 33) 黄飞霞, 陆怡衡, 丛莘, 劳力行, 翁庚民. 翁庚民运用扶阳法治疗失眠的经验总结. 中国民间疗法. 2018,03(26),102-104. DOI:10.19621/j.cnki.11-3555/r.2018.0365. 34) Shen, Y., Lao, L. Can acupuncture treat COVID-19 symptoms? Discussion of possible underline mechanisms. Acupuncture Today. July 2020.

Contributing Author 1) Shlay, J.C., Chaloner, K., Max, M.B., Flaws, B., Reichelderfer, P., Wentworth, D., Hillman, S., Brizz, B., Cohn, D.L. Acupuncture and amitriptyline for pain due to HIV-related peripheral neuropathy: a randomized controlled trial. Terry Beirn Community Programs for Clinical Research on AIDS. JAMA. 1998 Nov 11;280(18):1590-5. (Lao, L., contributing author) 2) MacPherson H, White A, Cummings M, Jobst KA, Rose K, Niemtzow RC; STRICTA Group. Standards for Reporting Interventions in Controlled Trials of Acupuncture: the STRICTA recommendations. J Altern Complement Med. 2002, 8(1):85-9. (Lao, L. contributing author) 3) MacPherson H, Altman DG, Hammerschlag R, Youping L, Taixiang W, et al. (2010) Revised STandards for Reporting Interventions in Clinical Trials of Acupuncture (STRICTA): Extending the CONSORT Statement. PLoS Med 7(6): e1000261. doi:10.1371/journal.pmed.1000261 (Lao, L. contributing author) 4) Vickers AJ, Cronin AM, Maschino AC, Lewith G, MacPherson H, Foster NE, Sherman KJ, Witt CM, Linde K; Acupuncture Trialists' Collaboration. Acupuncture for chronic pain: individual patient data meta-analysis. Arch Intern Med. 2012 Oct 22;172(19):1444-53. doi: 10.1001/archinternmed.2012.3654. (Lao, L. contributing author)

Book Chapters

1) Lao, L. Traditional Chinese Medicine, Part III, Chapter 12. Essentials of Complementary and Alternative Medicine. Wayne B. Jonas and Jeffery S. Levin, Eds. Philadelphia: Lippincott Williams & Wilkins, 1999 2) Lao, L., Berman, B., Ezzo, J., Hammerschlag, R. Assessing Clinical Efficacy of Acupuncture: Considerations for the Future Design of Clinical Trials in Acupuncture. Chapter 11 IN Stüx, G., and Hammerschlag, R. (eds.) Clinical Acupuncture--Scientific Basis. Berlin: Springer-Verlag, 2001 3) Ezzo, J., Lao, L., Berman, B. Assessing Clinical Efficacy of Acupuncture: What Has Been Learned from Systematic Reviews of Acupuncture? Chapter 7 IN Stüx, G., and Hammerschlag, R. (eds.) Clinical Acupuncture--Scientific Basis. Berlin: Springer-Verlag, 2001 4) Hammerschlag, R. Lao, L. Future Directions for Research on the Physiology of Acupuncture. Chapter 12 IN Stüx, G., and Hammerschlag, R. (eds.) Clinical Acupuncture--Scientific Basis. Berlin: Springer-Verlag, 2001 5) Hammerschlag, R., Langevin, H., Lao, L. Lewith, G. Physiological Dynamics of Acupuncture: Correlations and Mechanisms. Chapter 10. Acupuncture Research-Strategies for Establishing an Evidence Base. Huge MacPherson, Richard Hammerschlag, George Lewith, Rosa Schnyer (eds.). Philadelphia: Churchill Livingstone- Elsevier, 2007 6) Linde, K., Hammerschlag, R., Lao, L. Evidence overviews: the role of systematic reviews and meta-analyses. Chapter 11. Ac upunct ure Research-Strategies for Establishing an Evidence Base. Huge MacPherson, Richard Hammerschlag, George Lewith, Rosa Schnyer (eds.). Philadelphia: Churchill Livingstone- Elsevier, 2007 7) Bao, T, Lao, L, Bardia, A. Cancer Pain Control with Traditional Chinese Medicine. Chapter 8 IN William C.S. Cho (Editor), Supportive cancer care with Chinese medicine. London: Springer, 2010:169-225. 8) Zhang, R. and Lao, L. Modern cancer Research on Chinese Medicine: Acupuncture. Chapter 10 IN William C .S. Cho (Editor), Supportive cancer care with Chinese medicine. London: Springer, 2010: 253-270. 9) Chiaramonte, D and Lao, L. Integrating Chinese and Western Medicine in Cancer Treatment. Chapter 13 IN William C.S. Cho (Editor), Supportive cancer care with Chinese medicine. London: Springer, 2010: 341-362. 10) Ruixin Zhang, Lixing Lao. Acupuncture and Moxibustion in Animal Models of Cancer. Chapter 13 IN William C. S. Cho (Editor), Evidence-based Anticancer Complementary and Alternative Medicine. London: Springer, 2012: 291-311. 11) Lixing Lao, Ling Xu, and Shifen Xu. Traditional Chinese Medicine. Chapter 9 IN Alfred Längler, Patrick J. Mansky, Georg Seifert (Editors), Integrative Pediatric Oncology. London: Springer, 2013: 125-136. 12) Zhang J, Zhao B, Lao L. (eds.) Acupuncture and Moxibustion (International Standard Library of Chinese Medicine). Beijing, China: People’s Medical Publishing House; 2014. 13) Lixing LAO, Haiyong CHEN. Chapter 6 How to Design, Conduct and Report a Randomized Controlled Trial (RCT) on Acupuncture. Professional English for Traditional Chinese Medicine Research (Y Tong&L Lao). Beijing: People's health publishing house. 14) Lixing LAO, Wing Fai YEUNG. Chapter 7 Research topic design and grantsmanship. Professional English for Traditional Chinese Medicine Research (Y Tong&L Lao). Beijing: People's health publishing house. 15) Zhang J, Zhao B, Lao L. (eds.) Acupuncture and Moxibustion (International Standard Library of Chinese Medicine). USA. PMPH-USA (February 21, 2017). 16) Baixiao Zhao, Huanbin Du, Lixing Lao (Editor-In-Chief). English Textbook Series of Beijing University of Chinese Medicine: Acupuncture and Moxibustion. Beijing, China. People’s Medical Publishing House; 2017.

17) Tong Yao, Lao Lixing. (Editor-In-Chief)《中医科研英语教程》Beijing, China: People’s Medical Publishing House; 2018. 18) Lixing Lao, Mingxiao Yang. Evidence-Based Acupuncture and Mechanistic Studies of Acupuncture. Bern, Switzerland The Peter Lang Publishing Group; 2018. 19) Lixing Lao, Mingxiao Yang. Difficulties and Challenges Facing Clinical Acupuncture Trials. Bern, Switzerland The Peter Lang Publishing Group; 2018.

Abstracts/Proceedings 1) Berman, B.M., Lao, L., Anderson, R.W. Effects of acupuncture on post-operative dental pain. Poster presented at the Seventh World Congress on Pain, Paris, France. Abstract, pp. 432 (August, 1993) 2) Lao, L., Berman, B., Wong, R., Wynn, R.L. Effect of Electroacupuncture as an adjuvant for treating cyclophosphamide-induced emesis in ferrets. IN Era of Hope, Volume III: Proceedings of the Dept. of Defense Breast Cancer Research Program Meeting. (November, 1997) 3) Tulder, MW van, Cherkin, D.C., Berman, B., Lao, L., Koes, B.W. The Effectiveness of Acupuncture in the Treatment of Low Back Pain. Proceedings of International Society of Technology Assessment in Health Care, Ottawa, Canada. (1997) 4) Lao, L., Zhang, G., Berman, B. Electroacupuncture Attenuate Hyperalgesia and Modulates FOS Protein Expression with Unilateral Persistent Inflammation. Proceedings: Society for th Neuroscience 28 Annual Meeting. (November, 1998) 5) Zhang, G., Graczyk, Z., Ren, K., Stein, C., Berman, B., Lao, L. Local Naloxone Blockade of Acupuncture Analgesia: Peripheral Opiods Implicated. Proceedings: Society for Neuroscience th 29 Annual Meeting. (October, 1999) 6) Zhang, G., Zhang, R-X, Ren, K., Wang, X-Y., Berman, B., Lao, L. Parametric Studies Of The Effects Of Electroacupuncture On Persistent Inflammatory Hyperalgesia In Rats. International Scientific Conference On Complementary, Alternative And Integrative Medicine R esearch, San Francisco, CA (May, 2001) 7) Richardson, MA, Ezzo, J., Vickers, A., Allen, C., Lao, L., Zhang, G., Ramirez, G. Acupuncture for Chemotherapy Induced Nausea and Vomiting in Adults: A Systematic Review. International Scientific Conference On Complementary, Alternative And Integrative Medicine Research, San Francisco, CA (May, 2001) 8) Lao, L. Zhang, R-X, Zhang, G., Wang, X-Y., Berman, B., Ren, K., The Effect of Electroacupuncture (EA) on Persistent Inflammatory Pain in Rats: Animal Model, EA Parameters and Acupoint Specificity. Chinese Medicine Meets Modern Science: New York 21st Century Chinese Medicine Forum. New York. (August 11-12, 2001) 9) Lao, L., Zhang, R-X, Zhang, G., Wang, X-Y., Berman, B., Ren, K., Effects Of Electroacupuncture Parameters and Acupuncture Point Specificity On Persistent Inflammatory Hyperalgesia In Rats. Society for Acupuncture Research 8th Annual Meeting. Minneapolis, Minnesota. (October 19-20, 2001) 10) Zhang, G, Bausell, B, Lao, L., Handwerger, B. Consistency of TCM Rheumatoid Arthritis Diagnosis and Herbal Prescrip tion. Society for Acupuncture Research 8th Annual Meeting. Minneapolis, Minnesota. (October 19-20, 2001) 11) Zhang, R.-X.., Zhang, G., Wang, X., Berman, B., Ren, K. and Lao, L. The effects of electroacupuncture (EA) on persistent hyperalgesia and inflammation-induced Fos protein th expression in rats: A parametric study. Proceedings: Society for Neuroscience 31 Annual Meeting. San Diego, CA. (November, 2001) 12) Zhang, R-X, Wang, X-Y., Zhang, G., Berman, B., Ren, K., Lao, L. Antihyperalgesic And Anti-inflammatory Synergism Between Electroacupuncture And Morphine Or Indomethacin In Rat. International Scientific Conference On Complementary, Alternative And Integrative Medicine Research, Boston, MA (April, 2002) 36

13) Zhang, R-X, Wang, X-Y., Zhang, G., Berman, B., Ren, K., Lao, L. Antihyperalgesic synergism between electroacupuncture (EA) and morphine, indomethacin or MK-801. 10th World Congress on Pain, San Diego, USA (August 17-22, 2002) 14) Lao, L., Bausell, B ., Bahr-Robertson, M., Tkaczuk, K., Lee, W.L., Berman, B. A Controlled Study Using Acupuncture As An Adjuvant to Treat Chemotherapy-Induced Nausea And Vomiting. Era of Hope 2002 Department of Defense Breast Cancer Research Program Meeting. Orlando, Florida (September 25-28, 2002) 15) Lao, L. Teaching TCM and Acupuncture in America: Sharing Teaching Experience, st Proceedings (pp: 205-9): The 1 International Symposium on Education of Traditional Chinese Medicine. Beijing, China (November 2002) 16) Zhang, R-X, Wang, X-Y., Zhang, G., Berman, B., Ren, K., and Lao, L. Combinations of electroacupuncture (EA) with morphine or indomethacin synerg istically or additively alleviate th inflammation in rats. Proceedings: Society for Neuroscience 32 Annual Meeting. Orlando, FL. (November, 2002) 17) Zhang, R-X, Wang, X-Y., Zhang, G., Berman, B., Ren, K., and Lao, L. Parameter-dependent effects of electroacupuncture (ea) on hyperalgesia and fos protein expression in rats with nd persistent inflammatory pain. Soc. Neurosci. Abstr. 33 A nnual Meeting. New Orleans, LA. (November, 2003) 18) Fan, A.Y., Zhang, R-X., Wang, L-B., Berman B., and Lao, L. A Chinese herb BOSWELLIA CARTERII attenuates hyperalgesia and edema in rats with persistent inflammation. Soc. rd Neurosci. Abstr. 33 A nnual Meeting. New Orleans, LA. (November, 2003) 19) Eaton, K., Lao, L., Wegener, S., Palmer, J., Bennett, E., and Jacobs, M. The efficacy of electroacupuncture for acute pain management following total knee replacement. Society for Acupuncture Research 10th Annual Symposium. Cambridge, MA. (November 15-16, 2003) 20) Lao, L., Fan, A.Y., Zhang, R-X., Wang, L-B., Ma, Z-Z., Zhang, W-Y., Lee, D. and Berman, B. Chinese herb attenuates hyperalgesia and edema in rats with persistent inflammation, a comparison between boswellia carterii and modified huo-luo-xiao-ling dan. Society for Acupuncture Research 10th Annual Symposium. Cambridge, MA. (November 15-16, 2003) 21) Zhang, R-X, Lao, L#. Wang, X-Y., Ren, K., Berman, B., Electroacupuncture alleviates hyperalgesia in a bone cancer pain mouse model. Complementary Therapies and Cancer Care: A Research Symposium, London, United Kingdom (June 2004) 22) Furlan, A., Van Tulder, M., Cherkin, D., tsukayama, H., Lao, L., Koes, B., Berman, B.M. Acupuncture for low-back pain: An updated Cochrane systematic review. Cochrane Back Review Group, Toronto, Ontario (2004)

23) Zhao BX, W ang XJ, Lao, L., The Validation of a Newly Designed Placebo Moxibustion Device: A randomized controlled trial. Society for Acupuncture Research 11th Annual Symposium. San Francisco, CA. (October, 1-3, 2004) 24) Lao, L., Zhang, R-X, Wang, L., Bing. L., Wang, X-Y., Ren, K., Berman, B. Mechanisms of electroacupuncture anti-hyperalgesia in peripheral inflammation: opioid receptor involvement. Society for Acupuncture Research 11th Annual Symposium. San Francisco, CA. (October, 1-3, 2004) 25) F urlan, A., Van Tulder, M., Cherkin, D., Tsukayama, H., Lao, L., Koes, B., Berman, B.M. Acupuncture for low-back pain: An updated Cochrane systematic review. Society for Acupuncture Research 11th Annual Symposium. San Francisco, CA. (October, 1-3, 2004) 26) Leung WK, Wu JCY, Chan LS, Chan FKL, Xie H, Fung SSL, Liang SM , Lao L, Fong H, Berman B, Che CT, Sung JJY. Treatmetn of Diarrhea-predominant irritable bowel syndrome with traditional Chines medicine: a randomized double-blind placebo controlled trial. Presented at the Asian Pacific Digestive Week, October 4-7, 2004, Beijing, china. 27) Ziea, E., Wu, J., Lao, L., Ren, T., Yew, D., Sung, J. Effect of Neonatal Maternal Separation Stress (NMSS) on Pain Threshold and Neurochemical Responses of Colonic Mucosa and 37

Spinal Cord to Nocioceptive Colonic Balloon Distension in Adult Rats. Soc. Neurosci. Abstr. th 34 A nnual Meeting. San Diego, CA. (October, 23-27, 2004) 28) Fan, A.Y., Lao, L., Zhang, R-X., Zhou, A-N., Wang, L-B., Ma, Z-Z.,Zhang, W-Y., Lee, D., Moudgil, K.D. and Berman, B. -Arthritic effects of a Chinese herb boswellia carterii in lewis th rats with adjuvant arthritis. Soc. Neurosci. Abstr. 34 A nnual Meeting. San Diego, CA. (October, 23-27, 2004) 29) Zhang, R-X, Lao, L., Wang, L., Liu, B., Wang, X., Ren, K., Berman, B. M. Involvement of opioid receptors in electroacupuncture-produced anti-hyperalgesia in rats with peripheral th inflammation. Soc. Neurosci. Abstr. 34 A nnual Meeting. San Diego, CA. (October, 23-27, 2004) nd 30) Lao, L. Standard TCM Curriculum Requirements in the U.S. The 2 International Symposium on Tradi tional Chinese Medicine Education, Shanghai, China (Nove mber 2-3, 2004) 31) Klyushnenkova, E.N., Fan, A.Y., Jiang, S.P., Bausell, B., Alexander, R.B., Lao, L. Herbal Therapy With Anti-Cancer Formula (ACF) Delays Primary Tumor Development In Tramp-C2 Mouse Model Of Prostate Cancer. International Society of Biological Therapy of Cancer, 19th Annual Meeting, San Francisco, (November, 4-7, 2004) 32) Bausell, R.B., Lao, L., Bergman, S., Is Acupuncture Analgesia an Expectancy Effect? International Symposium in Oral Maxillofacial Surgery, Hawaii (Jan 31-Feb. 4, 2005) 33) Zhang, R.-X., Liu, B., Wang, L., Ren, K., Qiao, J.T., Berman, B.M., Lao, L. Spinal glial activation in a new rat model of bone cancer pain produced by prostate cancer cell inoculation th of the tibia. Soc. Neurosci. Program No. 169.2. Abstr. 35 A nnual Meeting. Washington, DC: (Nov. 12-16, 2005) 34) Liu, B., Zhang, R-X, Wang, L., Ren, K., Qiao, J., Berman, B. M., Lao, L., Electroacupuncture (EA) attenuates hyperalgesia in a rat model of bone cancer pain. Soc. Neurosci. Program No. th 623.3.Abstr. 35 A nnual Meeting. Washington, DC: (Nov. 12-16, 2005) 35) Zhang, R-X, Lao, L., Wang, L., Bing. L., Qiao, J., Ren, K., Berman, B. Mu opioid receptor-containing neurons and spinal gi/o-protein mediate electroacupuncture-produced anti-hyperalgesia in rats with hind paw inflammation. Society for Acupuncture Research 12th Annual Symposium. Albuquerque, NM. (October 21 – 23, 2005) 36) Shen, X, Ding, G , D eng, H., Wei, J., Z hao, L., Zhou, Y., L ao, L. Infrared radiation spectrums at acupuncture point nei guan (PC6) on patients with coronary heart disease. Society for Acupuncture Research 12th Annual Symposium. Albuquerque, NM. (October 21 – 23, 2005)

37) Shen, X, Ding, G, W ei, J., Z hao, L., Zhou, Y., Deng, H., Lao, L. The biophysical basis of traditional moxibustion. Society for Acupuncture Research 12th Annual Symposium. Albuquerque, NM. (October 21 – 23, 2005) 38) Ziea, E.T.C., Lao, L., Wu, J., Leung, R., Leung, W.K., Sung, J.J.Y. Electro-acupuncture significantly reduces cFos & serotonin (5HT) responsiveness of brain-gut axis to colorectal distension in rat model of visceral hyperalgesia. Abstract submitted for presentation in Digestive Disease Week 2005, Chicago. 39) Lao, L. Effect of Chinese herbs on persistent inflammation in rats, International Society of Chinese Medicine Conference: Chinese Medicine for the Prevention and Treatment of Contemporary Diseases: An Evidence-based Approach, Macao, China (April 3, 2005) 40) Lao, L., Manheimer, E., Berman, B. Systematic Reviews of Chinese Medicine, International Society of Chinese Medicine conference: Chinese Medicine for the Prevention and Treatment of Contemporary Diseases: An Evidence-based Approach, Macao, China (April 3, 2005) 41) Zhang, R., Li, B., Wang, L., Ren, K., Qiao, J., Berman, B.M., Lao, L. Georgia World Congress Center: Halls B3-B5; Electroacupuncture (EA) attenuates hyperalgesia and 38

inhibits IL-1β expression in a rat model of bone cancer pain, Soc. Neurosci. 36th th Annual Meeting, Atlanta, Georgia (October 14 , 2006). 42) Li, A., Zhang, R., Wang, Y., Zhang, H., Ren, K., Berman, B., Tan, M., Lao, L. Corticosterone mediates electroacupuncture-produced anti-edema in a rat model of th inflammation. Soc. Neurosci. 37 Annual Meeting. San Diego: (Nov. 3-7, 2007) 43) Zhang, R., Li, A., Liu, B., Wang, L., Ren, K., Zhang, H., Berman, B., Lao, L. IL-1ra alleviates inflammatory hyperalgesia through preventing phosphorylation of NMDA th receptor NR-1 subunit in rats. Soc. Neurosci. 37 Annual Meeting. San Diego: (Nov. 3-7, 2007) 44) Ziea, E., Wu, J., Yew, D., Chu, S., Leung, R., Lam, E., Lao, L., Berman, B., Sung, J. A Comparative Study of The Treatment Effect of Electroacupuncture (ST36) And Different Sham Acupunctures In An IBS Rat Model. 10 Years Post-NIH Consensus Conference, O-B-2 (Nov. 9-11, 2007). J Altern Complement Med. 2007:13(8):857-8 45) Shen, X., Zhao, L., Ding, G., Li, G., Wang, L., Lao, L. A Pilot Study of 650nm And 10.6μm Laser Acupuncture Irradiation On Patients With Osteoarthritis Of The Knee. 10 Years Post-NIH Consensus Conference, PI-8 (Nov. 9-11, 2007). J Altern Complement Med. 2007:13(8):865 46) Xu, L., Wei, P., Sun, D., Lao, L. An Analysis of The Quality of Reporting In 41 Randomized, Controlled Clinical Trials of Chinese Medicine For Cancer Pain. 10 Years Post-NIH Consensus Conference, PI-33 (Nov. 9-11, 2007). J Altern Complement Med. 2007:13(8):873-4 47) Zhang, R., Li, A., Liu, B., Wang, L., Wang, Y., Ren, K., Qiao, J., Berman, B., Lao, L. Electroacupuncture Attenuates Bone Cancer Pain And Inhibits Spinal Innterleukin-1βExpression In A Rat Model. 10 Years Post-NIH Consensus Conference, PⅡ-1 (Nov. 9-11, 2007). J Altern Complement Med. 2007:13(8):892 48) Li, A., Zhang, R., Wang, Y., Zhang, H. , Ren, K., Berman, B., Tan, M., Lao, L. Corticosterone Mediates Electroacupuncture-produced Anti-edema In A Rat Model of Inflammation. 10 Years Post-NIH Consensus Conference, PⅡ-4 (Nov. 9-11, 2007). J Altern Complement Med. 2007:13(8):893 49) Wei, J., Shen, X., Wang, T., Mao, H., Zhou, Y., Lao, L. Circadian Difference of Volt-Ampere Characteristics of Acupoint Daling(PC7). 10 Years Post-NIH Consensus Conference, PⅡ-35 (Nov. 9-11, 2007). J Altern Complement Med. 2007:13(8):903 50) Ziea, E., Wu, J., Yew, D., Chan, C., Leung, A., Leung R., Lao, L., Berman, B., Sung, J., Comparing Effects of 4 Different Acupoints On Serotoni n And C Fos Expression In The Brain-gut Axins In An IBS Rat Model. 10 Years Post-NIH Consensus Conference, PⅡ-65 (Nov. 9-11, 2007). J Altern Complement Med. 2007:13(8):913 51) Chan, S., Zhao, M., Fong, H., Lao, L. Che, C. The Anti-spasmodic Effect of Magnolia Officinalis Is Determined By Its Magnolol And Honokiol Contents. 10 Years Post-NIH Consensus Conference, PⅡ-76 (Nov. 9-11, 2007). J Altern Complement Med. 2007:13(8):917 52) Tan, M., Lao, L., Fang, H., Zhang, R., Chen, K., Berman, B. Statistical Issues In Evaluating The Effectiveness of TCM: From Animal Models To Clinical Trials. 10 Years Post-NIH Consensus Conference, PⅡ-88 (Nov. 9-11, 2007). J Altern Complement Med. 2007:13(8):920 53) Lao, L. Evidenced-Based Medicine in Acupuncture. The 20th Anniversary of World Federation of Acupuncture- Mosibustion Societies (WFAS) and International Acupuncture Congress- Abstracts. Beijing, China. (Oct.20-22, 2007): P15-29 54) Lao, L. Acupuncture Clinical Studies and Evidence Based Medicine - An Update. 2007’ In ternational Forum of Acupuncture Medical Specialists. China Academy of Chinese Medical Sciences. Beijing, China (Nov.19-21, 2007):P23-33 39

55) Yousuf, S.; Frick, K.D.; Spencer, C.; Lao, L.; Berman, B.M.; Steinwachs, D.M.; Hochberg, M.C. Cost effectiveness of traditional Chinese acupuncture as adjunctive therapy in osteoarthritis of the knee. Osteoarthritis and Cartilage. 2007; Volume 15, Supplement C, Page C36, Abstract #38. DOI: 10.1016/S1063-4584(07)61674-4 (Podium presentation at the December 2007 World Congress on Osteoarthritis, Ft. Lauderdale, FL, 6-9 December 2007.) 56) ZHANG, RX, LIU, B, LI, A, WANG, Y, REN, K, QIAO, JT, BERMAN, BM, LAO, L. Interleukin 1β facilitates bone cancer pain in rats by enhancing NMDA receptor NR-1 th subunit phosphorylation Neurosci. 38 Annual Meeting Washington DC (Nov 19, 2008) 57) LI, A, LAO, L, WANG, Y, XIN, J, REN, K, BERMAN, BM, TAN, M , ZHANG, RX. Electroacupuncture activates corticotrophin-releasing hormone-containing neurons in the paraventricular nucleus of the hypothalamus to alleviate edema in a rat model of th inflammation Neurosci. 37 Annual Meeting Washington DC (Nov 18, 2008) 58) L ee DY-W, Lao L, Moudgil K, Fong H, Berman B: Treatment of Osteoarthritis with HLXLD: A Translational TCM Study in the US. In: 9th Meeting of Consortium for Globalization of Chinese Medicine (CGCM): August 23-25, 2010; Hong Kong; 2010. 59) Bao T, Medeiros M, Zhang R, Lao L, Badros A: Improvement of painful bortezomib-induced peripheral neuropathy following acupuncture treatment in a case series of patients with multiple myeloma. 2011 American Soceity of Clinical Oncology (ASCO) Annual Meeting. Chicago, IL (June 3- 7, 2011) 60) Xu S, Shen X, Li S, Lao L. Effects of electroacupuncture on depression in a rat model. Neuroscience, Poster VV74, 296.10. November, 13,2011. Washington, DC. 61) Lao L, Y. Zhang, X.Y. Shen, A. Li, J. Xin, B.M. Berman, M.Tan, K, Ren, R.X. Zhang (2012) Acupuncture alleviates affective dimension of pain in a rat model of inflammatory hyperalgesia. International Research Congress on Integrative Medicine and Health, Portland, OR , May 15-18, 2012. 62) R.X. Zhang, X.Z. Meng, Y. Zhang, X.Y. Shen, A. Li, B.M. Berman, K, Ren, P.K. Wei, L. Lao, (2012) Electroacupuncture alleviates hyperalgesia by inhibiting spinal interleukin-17 in an inflammatory pain rat model. International Research Congress on Integrative Medicine and Health, Portland, May 15-18, 2012. 63) Wang Lizhen, Zhao Ling, Zhang Haimeng, Wu Fan, Lao Lixing, Shen Xueyong, (2012) The Effect of 650nm and 10.6μm Laser Radiation on Knee Osteoarthritis C57 Black Mouse in serum PGE2 and HA. International Research Congress on Integrative Medicine and Health, Portland, OR , May 15-18, 2012. 64) Wu Fan, Zhao Ling, Wang Lizhen Zhang Haimeng, Lao Lixing, Shen Xueyong, (2012) Observation on effects of 10.6μm laser moxibustion in patients with knee osteoarthritis: A double-blind, randomized, controlled study. International Research Congress on Integrative Medicine and Health, Portland, OR, May 15-18, 2012. 65) ze SCW, Lu J, Lai YM, Wong KL, Lao L, Leigh AB, Zhang L, Zhang Y, Ng TB: The magic of Chinese yam. In ITC InnoCarnival 20132013. 66) Zhang L, Ng TB, Lao L, Zhang Y, Cheung HP, Sze CWS: Aberrantly up-regulated expression of transferrin and ferritin induces iron overload and thereby ovarian aging in Sprague-Dawley rats (Sprague-Dawley). In 8th Pong Ding Yuen International Symposium on Traditional Chinese Medicine, 2nd International Chinese Symposium on Free Radical Research & 6th Symposium for Three Districts of Cross-straits on Free Radical Research2014. 67) Zhang L, Cheung HP, Lee CKF, Ng TB, Zhang Y, Lao L, Sze CW: Proteomics analysis of the ovarian tissues of Sprague-Dawley Rats of different ages to identify aging-associated changes. In International Symposium on Healthy Aging, ISHA 20142014. 68) Wang S, Ng TB, Lao L, Sze CW: Combing network phytochemistry with networking pharmacology approaches to elucidate the action mechanism of Traditional Chinese Medicine 40

Formula: chemical constitutes of erxian decoction up-regulated estrogen receptor expression and induced estradiol-biosynthesis for menopause as a study model. In Meeting of Consortium for Globalization of Chinese Medicine, CGCM 20142014. 69) Wang S, Cheung HP, Ng TB, Lao L, Zhang Y, Sze CWS: Screening and mechanistic study of estradiol-stimulating fractions derived from erxian decoction in aged sprague-dawley rats. In 8th Pong Ding Yuen International Symposium on Traditional Chinese Medicine, 2nd International Chinese Symposium on Free Radical Research & 6th Symposium for Three Districts of Cross-straits on Free Radical Research2014. 70) Sze SCW, Zhang L, Cheung HP, Wang S, Lao L, Ng TB: Proteomics analysis of the effects of erxian decoction on retarding ovarian aging. In Meeting of Consortium for Globalization of Chinese Medicine, CGCM 20142014. 71) Sze CWS, Lee CKF, Shaw PC, Ng TB, Wong RNS, Lao L, Zhang Y: DNA microarray for authentication of medicinal dendrobium species. In BIT's 3rd Annual Conference & Expo of AnalytiX-20142014. 72) Lu J, Wong RNS, Zhang L, Lao L, Zhang Y, Ng TB, Sze CW: Comparative analysis of estradiol-stimulating proteins from four different Dioscorea species. In Meeting of Consortium for Globalization of Chinese Medicine, CGCM 20142014. 73) Liu J, Tang SCW, Sze CWS, Lao L, Ho JCM, Lee CKF, Zhang Y: Traditional Chinese Medicine is a promising alternativ e for t he management of diabetic nephropathy. In 8th Pong Ding Yuen International Symposium on Traditional Chinese Medicine, 2nd International Chinese Symposium on Free Radical Research & 6th Symposium for Three Districts of Cross-straits on Free Radical Research2014. 74) Li L, Ng CY, Wang N, Cheung F, Wang L, Zhang Z, Lao L, Lain D, Feng Y: A new teaching and learning module of Chinese Medicine on-site field trip combing with moodle e-learning platform. In International Postgraduate Symposium on Chinese Medicine, IPSCM 20142014. 75) Leigh AB, Lai YM, Zhang Y, Lao L, Sze CWS: Comparison of effectiveness between CAM118 granules and granule mixtures of its individual herbs at different temperatures on human colon carcinoma HT-29 cells. In 8th Pong Ding Yuen International Symposium on Traditional Chinese Medicine, 2nd International Chinese Symposium on Free Radical Research & 6th Symposium for Three Districts of Cross-straits on Free Radical Research2014. 76) Feng Y, Li L, Lao L: How to establish and develop a School of Chinese Medicine in a Westernized University: attentions of the University of Hong Kong. In University President Forum for Higher Education in Chinese Medicine. Changsha2014. 77) Cheung F, Ho SY, Lam TH, Lao L, Feng Y: Factors associated with preference to use Chinese Medicine in people with chronic diseases in Hong Kong. In Meeting of the Consortium for Globalization of Chinese Medicine, CGCM 20142014. 78) Chen H, Feng Y, Lao L: Chinese integrative medicine: inclusion of a Chinese medicine programme in a conventional medical institute. In 25th Anniversary Foundation Meeting of National CM Higher Education Associaton2014. 79) Zhao Jia, Lao Lixing, Rong Jianhui, (2015) Botanical drug puerarin attenuates 6- hydroxydopa mine (6-OH DA)-induced neurotoxicity via upregulating mitochondrial enzyme arginase-2, ASPET Annual Meeting during Experimental Biology 2015, Boston, Massachusetts, USA, March 28 – April 1, 2015. 80) Gorman Peter, Estores Irene, Chen Kevin, Jackson Brian, Lao Lixing. (2015) Auricular Acupuncture for Spinal Cord Injury Related Neuropathic Pain: A Pilot Controlled Clinical Trial. Society for Acupuncture Research 2015 International Conference, Boston, MA, November 12–14, 2015. 81) Liu Juntian, Zhao Baixiao, Huang Chang, Liu Yaomeng, Lao Lixing. (2015) Effects of Different Parts of Moxibustion on Mitochondrial Activities in APP/PS 1 Mice. Society for Acupuncture Research 2015 International Conference, Boston, MA, November 12–14, 2015. 41

82) Niu Xuan, Bai Lijun, Sun Chuanzhu, Wang Shan, Lao Lixing. (2015) Heterogeneous Neural Mechanism Underlying Ipsi- and Contra-lateral Acupuncture Analgesia in the Capsaicin-induced Pain Model. Society for Acupuncture Research 2015 International Conference, Boston, MA, November 12–14, 2015. 83) Zhang Ruixin, Wu Fan, Cheng Ke, Deng Haiping, Wang Lizhen, Lao Lixing, Berman Brian M, Shen Xueyong. (2016) Carbon Dioxide Laser Treatment Inhibits Monocyte Chemotactic Protein to Alleviate Knee Osteoarthritis Pain in Rats. The International Congress on Integrative Medicine and Health (ICIMH), Las Vegas, Nevada, USA May 17–20, 2016. 84) Estores Irene, Chen Kevin, Jackson Brian, Lao Lixing, Gorman Peter. (2016) Auricular Acupuncture for Spinal Cord Injury Related Neuropathic Pain: A Pilot Controlled Clinical Trial. The International Congress on Integrative Medicine and Health (ICIMH), Las Vegas, Nevada, USA May 17–20, 2016. 85) Zhao Jia, Lao Lixing, Rong Jianhui, (2016) Plant Natural Product Puerarin Ameliorates Depressive Behaviors and Chronic Pain in Mice with Spared Nerve Injury (SNI). New Zealand Applied Neurosciences Conference 2016, Auckland, New Zealand, November 24–26, 2016. 86) Lao L, Chen H, Wang H, Lam S: Evidence-base Medicine in Acupuncture Research: Challenges and Opportunities. In Meeting of the Consortium for Globalization of Chinese Medicine2016. 87) Zhao Jia, Rong Jianhui, Lao Lixing, (2017) Unexpected antidepressant and analgesic activities of Chinese medicine puerarin and its molecular targets. 16th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), Guangzhou, China, August 18 - 20, 2017. 88) Wang X, Ng TB, Lee CKF, Lai YM, Lao LX, Sze CWS: Use of rodent models in the study of menopausal symptoms: A review of experimental studies. In 11th European Congress on Menopause and Andropause (EMAS 2017). Amsterdam, The Netherlands: European Congress on Menopause and Andropause.; 2017. 89) Mu JL, Furlan AD, Lam WY, Hsu MY, Ning Z, Lao L: Acupuncture for chronic non-specific low back pain: a systematic review and meta-analysis. In Meeting of Consortium for Globalization of Chinese Medicine (CGCM). pp. 25. Guangzhou, China: The 16th CGCM conference.; 2017:25. 90) Chen H, Ning Z, Wong N, Ng BFL, Ziea ETC, Lao L: Types of control in acupuncture clinical trials might affect the conclusion of the trials. In Society for Acupuncture Research (SAR) Conference2017. 91) Chen H, Ning Z, Lam WL, Zhao Y, Lun WM, Ng BFL, Ziea ETC, Lao L: How to design a control in acupuncture randomized controlled trials. In The 16th Me eting of Consortium for Globalization of Chinese Medicine 20172017. 92) Lam Wing Lok, Yeung Wing Fai, Lau Chak Sing, Chen Haiyong, Lao Lixing. (2017) Electroacupuncture in Ankylosing Spondylitis pain control: A single-arm pilot study. The 10th Pong Ding Yuen International Symposium on Traditional Chinese Medicine, Hong Kong, December 1-3, 2017. 93) Meng Wei, Lian Wei Ling, Zhang Yan Bo, Zhang Zhang Jin, Lao Lixing. (2018) A Double-blind, Randomized, Two-Dose Trial of Chinese Medicine, Tum or-Shrinking Decoction (TSD), in Patients with Symptomatic Uterine Fibroids. 2018 International Congress on Integrative Medicine and Health, Baltimore, MD, USA, May 8-11, 2018. 94) Lam Wing Lok, Wang Haiyi, Zhang Jialing, Zhao Yingke, Mu Jinglan, Hsu Marcos, Yeung Wing Fai, Chen Haiyong, Lao Lixing. (2018) Acupuncture in Postoperative Pain management– Results of A systematic review and meta-analysis. The 17th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), Kuching, Sarawak, Malaysia, August 8-10, 2018. 95) Lam Wing Lok, Yeung Wing Fai, Lau Chak Sing, Chen Haiyong, Lao Lixing. (2018) Electroacupuncture in Ankylosing Spondylitis pain control: Results of a single-arm pilot study. 42

The 17th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), Kuching, Sarawak, Malaysia, August 8-10, 2018. 96) Lao Lixing. Challenges of Chinese Medicine Clinical Trials: How to interpret the data from “negative” R CTs? The 3rd International Symposium on Phytochemicals in Medicine and Food, Kunming, Yunnan, China, August 25-30, 2018. 97) Yin X, Gou M, Xu J, Dong B, Yin P, Masquelin F, Wu J, Xu S*, Lao Lixing*. Efficacy and safety of acupuncture treatment on primary insomnia: a randomized controlled trial. The ICMART-iSAMS 2018 World Congress on Medical Acupuncture and Related Techniques, Munich, Germany, September 07-09, 2018. 98) Yin X, Gou M, Xu J, Dong B, Yin P, Masquelin F, Wu J, Xu S*, Lao Lixing*. Efficacy and safety of acupuncture treatment on primary insomnia: a randomized controlled trial. The World Acupuncture Day, Paris, France, November 15-17, 2018.

TEACHING

Mentoring (visiting scholars): 1) 2006 - 2007 Yi Wang (China)- research in TCM and kidney diseases 2) 2006 - 2007 Ling Xu (China)- research in TCM and cancer 3) 2007 - 2007 Ling Zhao (China)– research in laser acupuncture 4) 2008 - 2009 Euiju Lee (Korea) – research on diagnosis 5) 2008 - 2009 Yoo Jung Hee (Korea)- research on diagnosis 6) 2009 - 2009 Corey Miller (USA)- research on TCM and acupuncture 7) 2009 - 2009 Timothy Kirk Miller (USA)- research on TCM and acupuncture 8) 2009 - 2009 Ari Ojeda Ocampo More (Brazil) - research on acupuncture 9) 2010 - 2010 Yichen Zhou (China) - undergraduate research on oversea TCM 10) 2010 - 2011 Serng B. Pak (Korea) - general research 11) 2010 - 2011 Xianze Meng (China) - research on TCM clinical and basic science 12) 2010 - 2011 Shifen Xu (China) – research on acupuncture 13) 2011 – 2011 Ming Zhang (China) – research on TCM and cancer 14) 2011 - 2011 Ana Flavia Lima (Brazil)- resident fellowship clinical shadowing 15) 2011 – 2011 Jessica Liu (Brazil)- undergraduate research 16) 2 011 – 2011 William Chang (USA)- high school student intern lab training 17) 2011 - 2012 Rikka Saito (Japan) – lab basic science research 18) 2 011 - 2012 Tao Liu (China) - research in TCM and placebo 19) 2011 - 2012 Dong-Won Shin (Korea) – lab basic science research 20) 2012 - 2013 Ke Cheng (China)– research in acupuncture and systematic review 21) 2012 - 2013 Lizhen Wang (China) – research on laser moxibustion 22) 2 012 - 2013 Jie Gao (China) - general research in TCM 23) 2 012 - 2013 Yi Li (China) - general research on acupuncture 24) 2012 - 2013 Qin Wang (China) – lab research in cancer pain 25) 2013 - 2014 Jiaxu Chen (China) - general research in TCM 26) 2013 - 2014 Miao Wang (China) - general research in TCM 27) 2015- 2016 Haiyi Wang (China) - general research in TCM

Supervisor (RPg): 1) 2014-presentWing Lok Lam (HK) – Ph.D. student, research on acupuncture 2) 2 015-presentZhao Yingke (China) – Ph.D. student, research on acupuncture 3) 2016-present Ning Zhipeng (China)-Mphil/Ph.D. student, research on acupuncture 4) 2017-present Chen Jie (China) – Ph.D. student, research on osteoarthritic pain 5) 2017-present Yuan Li (China) – PhD student, traditional Chinese medicine 43

6) 2017-present Zhang Jialing (China) – Ph.D. student, research on acupuncture

Supervior (PDFs): 1) 2015-2016 Wing Fai Yeung (HK) - postdoctoral fellow, research on acupuncture and low back pain 2) 2015-2017 Mu Jinglan (China) - postdoctoral fellow, research on acupuncture and low back pain 3) 2016-2019 Zhao Jia (China) - postdoctoral fellow, research on Chinese herb and neuropathic pain 4) 2016-2019 Lo Kui-Qing (HK) - postdoctoral fellow, research on Ancient Literature 5) 2017-2019 Yang Mingxiao (China) - postdoctoral fellow, research on acupuncture and clinical epidemiology

Co-supervisor (RPg): 1) 2014-2018 Chan Kam Wa (HK) – PhD student, research on integrative medicine 2) 2013-2018 Wai Chung Clara (HK) – PhD student, traditional Chinese medicine 3) 2015-2018 You Jieshu (China) – PhD student, traditional Chinese medicine 4) 2016-2018 Guo Wei (China) – PhD student, traditional Chinese medicine

PRESENTATIONS

1990 1) Lao, L., Franklin, R.B. and Costello, L.C., Characteristics of a Low Affinity Aspartate Transpo rter in Rat Ventral Prostate Epithelial Cells. FASEB Annual Conference, Washington D.C. (1990)

1993 2) Lao, L. Issues and challenges in acupuncture research. Lecture and discussion in 1993 Symposium: Research and clinical Applications in Acupuncture, sponsored by the American Academy of Medical Acupuncture, Marriott Inner Harbor, Baltimore, MD, (May, 1993) 3) Lao, L. and Lu, M. Continuing Education Course: Acupuncture and its Role in Palliative Care, Present ed at the Second Annual Collaborative Approaches in Palliative Care, Fairfax Hospital, Northern Virginia, (December 8, 1993) 4) Lao, L. and Wong, R.H., Guest Lecturer for Conjoint Sciences II: Acupuncture and its Role in Dentistry, Baltimore College of Dental Surgery, Dental School, UMAB, (December 1, 1993)

1994 5) Lao, L. Alternative techniques in chronic pain: Acupuncture. Guest lecturer for Pain Management Seminar, St. Agnes Hospital, Baltimore, Maryland. (February, 199 4) 6) Lao, L. Safety in Acupuncture. Invited speaker for Workshop on Acupuncture, Office of Alternative Medicine, National Institutes of Health, and Food and Drug Administration, Rockville, Maryland. (April, 1994) 7) Lao, L. Classical Acupuncture Techniques and Devices. Invited speaker for Workshop on Acupuncture, Office of Alternative Medicine, National Institutes of Health, and Food and Drug Administration, Rockville, Maryland. (April, 1994) 8) Lao, L. Chinese Herbal Medicine. Invited speaker for Department of Pharmaceutical Science s Graduate Student Seminar, School of Pharmacy, University of Maryland at Baltimore. (May, 1994) 44

9) Lao, L. Methodology of Acupuncture in Clinical Trials. Fifth Symposium on Acupuncture Analgesia and Acupuncture Anesthesia, Wuhan, China. (September, 1994) 10) Berman, B.M., Lao, L., Wong, R.H., Anderson, R.W., Langenberg, P., Greene, M., and Hochberg, M.D. Effect o f Acupuncture on Osteoarthritis: A Pilot Study. Fifth Symposium on Acupuncture Analgesia and Acupuncture Anesthesia, Wuhan, China. (September, 1994) 11) Lao, L., Bergman, S., Langenberg, P., Wong, R.H., and Berman, B. The Effect of Acupuncture on Post-Operative Oral Surgery Pain. Fifth Symposium on Acupuncture Analgesia and Acupuncture Anesthesia, Wuhan, China. (September, 1994) 12) Lao, L. Acupuncture and Dental Pain. Guest lecturer. U. Md. School of Dentistry. (Nov. 1994)

1995 13) Lao, L. Acupuncture and Postoperative Oral Surgery Pain. NIH Exploratory Grant Awardees Conference, Bethesda, MD. (April 1995) 14) Lao, L. Medical Training and Education. Panelist. The First International Congress on Alternative & Complementary Medicine. Arlington, VA. (May 1995) 15) Lao, L. Efficacy of Acupuncture on Post-operative Oral Surgery Pain. The Second Conference on World Traditional Medicine, Las Vegas, NV. (May, 1995) 16) Lao, L. The Effect of Acupuncture on Posto perative Oral Surgery Pain.. National Acupuncture and Oriental Medicine Alliance. Washington, DC. (May, 1995) 17) Lao, L. Acupuncture Research. Panel Discussion. National Acupuncture and Oriental Medicine Alliance. Washington, DC. (May, 1995) 18) Lao, L. Issues Facing our Profession. A Researcher’s Perspective. Panel Discussion. National Acupuncture and Oriental Medicine Alliance. Washington, DC. (May, 1995) 19) Lao, L. Acupuncture and Postoperative Oral Surgery Pain. NIH Methodology Conference. Bethesd a, MD. (August 1995) 20) Lao, L. Antiemetic Effect of Acupuncture on Chemotherapy-induced Nausea and Vomiting. Chinese Medical and Health Association Annual Scientific Symposium, Rockville, Maryland. (September, 1995) 21) Lao, L. Acupuncture and Dental Pain. Guest lecturer. U. Md. School of Dentistry. Baltimore, MD. (November, 1995)

1996 22) Lao, L. Chinese Medicine and HIV/AIDS. Baltimore Nurses’ Forum on AIDS. Baltimore, MD. (February 14, 1996) 23) Lao, L. The Effect Of Acupuncture On Post-Operative Oral Surgery Pain. NIH Alternative MedicineProgram Advisory Council (AMPAC). Bethesda, MD (June 13-14, 1996) 24) Lao, L. Controlled Acupuncture Clinical Trial on Osteoarthritis of the Knee. -- Awarded as an Excellent Paper. The 4th World Conference on Acupuncture, New York. (September 18-22, 1996)

1997 25) Lao, L. Acupuncture. Guest speaker. Med-Peds Conference. U. Md. School of Medicine. (February 6, 1997) 26) Lao, L. Acupuncture and Arthritis. Guest speaker, Grand Rounds; Rheumatology Dept. Johns Hopkins University School of Medicine. Baltimore, MD (March 25, 1997) 27) Lao, L. Acupuncture Technique/Demonstration. National Center for Health Statistics. Washington, D.C. (May 5, 1997) 28) Lao, L. Acupuncture in Western Medicine. Medicine Grand Rounds. University of MD School of Medicine. Baltimore, MD. (May, 1997) 45

29) Lao, L. Acupuncture for Dental and Post-Operative Pain. NIH Consensus Development Conference on Acupuncture. Bethesda, MD (November, 1997)

1998 30) Lao, L. Testimony on the Use of Endangered Species in Chinese Medicines for the Rhinoceros and Tiger Conservation Act. U.S. House of Representatives Committee on Resources. Washington, D.C. (February, 1998) 31) Lao, L. Acupuncture in Medicine. Grand Rounds. Community Hospital, Laurel, MD. (April, 1998) 32) Lao, L. Acupuncture Research Methodology. (Invited Lecturer). Seminar. Shanghai University of Traditional Chinese Medicine. Shanghai, China. (June, 1998) 33) Lao, L. Recognition of Acupuncture by the NIH. (Invited Speaker) Third International Conference on Integrated and Bioenergetic Medicine. College Park, MD. (July, 1998) 34) Lao, L. Electroacupuncture Attenuates Hyperalgesia and Modules Fos-protein Expression in Rats with Unilateral Persistent Inflammation. Society for Acupuncture Research Annual Meeting. Palo Alto, CA (September, 1998) 35) Lao, L. Acupuncture Research at the University of Maryland. Society for Acupuncture Research Annual Meeting. Palo Alto, CA. (Sept. 1998) 36) Lao, L. Neijing and the Ro le of Emotion in TCM. Seminar. Maryland Institute of Traditional Chinese Medicine. Bethesda, MD. (December, 1998)

1999 37) Lao, L. Acupuncture. Building Bridges: Relationship-Centered Care as the Link between Convention and Complementary Medicine. Johns Hopkins University School of Medicine. Baltimore, MD (March, 1999) 38) Lao, L. Placebo-Controlled Acupuncture Clinical Trial on Post-Operative Oral Surgery Pain. American Dental Society of Anesthesiology Conference. Washington, D.C. (April, 1999) 39) Lao, L. Acupuncture in Oral Surgery. Moving with the Sun ’99: Global Telemedicine Conference. In cooperation with Chinese Academy of Traditional Chinese Medicine, Beijing, and Prince of Wales Hospital, London. Baltimore, MD. (April, 1999) 40) Lao, L. Acupuncture and Pain Control. Walter Reed Army Hospital. Bethesda, MD. (May, 1999) 41) Lao, L. Acupuncture Treatment for Osteoarthritis. National Acupuncture and Oriental Medicine th Alliance 6 Annual Conference. Safety Harbor, FL. (May, 1999) 42) Lao, L. Physiological Basis of Acupuncture. Society for Acupuncture Research Annual Meeting. Irvine, CA. (May, 1999) 43) Lao, L. Acupuncture Basic Science Research: A New Animal Model. Seminar. Center for Addictions and Alternative Medicine Research. Minneapolis, MN. (June, 1999) 44) Lao, L. Acupuncture Research. (Invited Lecturer) Conference. Yan Huang Chinese Traditional Medical Hospital. Beijing, China. (August, 1999) 45) Lao, L. Traditional Chinese Medicine and Wildlife Conservation (panelist) Health planet, health people conference. Beijing, China. (October 1999)

2000 46) Lao, L. Effect of Electroacupuncture as an Adjuvant for Treating Chemotherapy-Induced Emesis American Cancer Society Science Writers Seminar Tampa, FL. (March, 2000) 47) Lao, L. Acupuncture History and Safety Issues. Invited speaker for Complementary & Alternative Medicine in Cardiovascular, Lung & Blood Research, NIH National Center for Complimentary and Alternative Medicine, National Heart, Lung an d B lood Institutes, Bethesda, Maryland. (June, 2000) 46

48) Lao, L. Effect of Electroacupuncture on Inflammation-induced Persistent Pain in Rats. (Invited Lecturer). Shanghai University of Traditional Chinese Medicine. Shanghai, China. (August, 2000) 49) Lao, L., A progress report on NCCAOM Center for Arthritis. Society for Acupuncture Research 7th Annual Symposium. Baltimore, MD. (October, 21-22, 2000)

2001 50) Lao, L. Testimony on Training, Education, Credentialing and Licensing of Complementary and Alternative Medicine Practice (Invited Speaker). White House Commission on Complementary and Alternative Medicine Policy. Washington, D.C. (February, 2001) 51) Lao, L. Strategies For Incorporating Conventional Medicine And TCM Diagnostic Criteria Into Acupun cture Research (Invited Speaker). International Symposium on Acupuncture Research Methodology, Exeter, UK. (July 2-4, 2001) 52) Lao, L. Designing acupuncture trials: one size does not fit all. (Invited Speaker). International Symposium on Acupuncture Research Methodology, Exeter, UK. (July 2-4, 2001) 53) Lao, L. Strategies For Incorporating Conventional Medicine And TCM Diagnostic Criteria Into Acupuncture Research (Invited Speaker). International Symposium on Acupuncture Research Methodology, Exeter, UK. (July 2-4, 2001) 54) Lao, L. Designing acupuncture trials: one size does not fit all. (Invited Speaker). International Symposium on Acupuncture Research Methodology, Exeter, UK. (July 2-4, 2001) 55) Lao, L. The Effect of Electroacupuncture (EA) on Persistent Inflammatory Pain in Rats: Animal Model, EA Parameters and Acupoint Specificity. (Invited Speaker). Chinese Medicine Meets Modern Science: New York 21st Century Chinese Medicine Forum. New York. (August 11-12, 2001) 56) Lao, L. Effects Of Electroacupuncture Parameters and Acupuncture Point Specificity On Persiste nt Inflammatory Hyperalgesia In Rats. (Presenter). Society for Acupuncture Research 8th Annual Meeting. Minneapolis, Minnesota. (October 19-20, 2001) 57) Lao, L. Acupuncture in Primary Care. (Conference Faculty). Contemporary Forums: Alternative and Complementary Therapies. Washington, D.C. (October 11-12, 2001) 58) Lao, L. Hyperalgesia in rats: Elecroacupuncture parameters and acupoint specificity. 8th Annual Symposium Society for Acupuncture Research. Minneapolis, MN (October 2001) 59) Lao, L. Workshop: Placebo/sham acupuncture procedures: Group exercise in credibility th testing of placebo/sham needling procedures. 8 Annual Symposium Society for Acupuncture Research. Minneapolis, MN (October 2001) th 60) Lao, L. Panel Chairman, Reports on Research Conferences. 8 Annual Symposium Society for Acupuncture Research. Minneapolis, MN (October 2001) th 61) Lao, L. Future Directions in AOM Research. 8 Annual Symposium Society for Acupuncture Research. Minneapolis, MN (October 2001) 62) Lao, L. Rheumatoid arthritis: Consistency of TCM diagnosis and herbal prescriptions. 8th Annual Symposium Society for Acupuncture Research. Minneapolis, MN (October 2001) 2002 63) Lao, L. National Cancer Institute Panel Meeting. Acupuncture Clinical Trials: Challenges and Strategies Bethesda, MD (January 2002) 64) Lao, L. Research Methodology in Acupuncture and TCM- An One Week Seminar (Invited speaker), Beijing University of Traditional Chinese Medicine, Beijing, China (June 2002) 65) Lao, L. Research Methodology and Evidence Based Medicine in Acupuncture and TCM (Invited speaker), Shanghai University of Traditional Chinese Medicine, Shanghai, China (July 2002)

66) Lao, L. Development of Research Programs at Acupuncture Schools and Clinics: Challenges th and Opportunities (Group Discussion Leader), Society for Acupuncture Research 9 Annual Symposium, Seattle, WA (October 2002) 67) Lao, L. Synergistic and Additive Effects of Electroacupuncture and Morphine or Indomethacin in Rats with Hyperalgesia and Inflammation (Invited speaker) Society for th Acupuncture Research 9 Annual Symposium, Seattle, WA (October 2002) 68) Lao, L. Bridging the Gap Between acupuncture clinical Trials and Clinical Practice (Invited rd speaker), 3 TWGHs-CUHK Eddie Wang Symposium on Complementary Chinese and Western Medicine-Integrated Approach, Hong Kong, China (October 2002) 69) Lao, L. Challenges and Issues in TCM Research: Can a Western Ruler Measure Eastern Distances? (Invited speaker), Hong Kong Health, Welfare and Food Bureau, U.S. National Institute of Health, and University of Maryland, Hong Kong, China (October 2002) 70) Lao, L. & Berman, B. Acupuncture and Pain: Evidence-based Medicine (Invited speaker), Shanghai University of Traditional Chinese Medicine, Shanghai, China (November 2002) 71) Lao, L. Acupuncture: Future Directions for Clinical Research on Acupuncture (Invited th speaker), 6 Congress of the Brazilian Society of Medical Acupuncture, Gramado -RS, Brazil (December 2002) th 72) Lao, L. Acupuncture: Physiology of Acupuncture (Invited speaker), 6 Congress of the Brazilian Society of Medical Acupuncture, Gramado -RS, Brazil (Decem ber 2002) th 73) Lao, L. Acupuncture: Evidence-based Medicine (Invited speaker), 6 Congress of the Brazilian Society of Medical Acupuncture, Gramado -RS, Brazil (December 2002)

2003 74) Lao, L. Cancer as a Disorder of the Human Energy System (Invited commentator), Comprehensive Cancer Care 2003, Washington DC (April 2003) 75) Lao, L. Effects of Electroacupuncture on Persistent Inflammatory Hyperalgesia in Rats, NIH National Center for Complementary & Alternative Medicine, Center Directors’ Meeting, Ann Arbor, Michigan (June 2003) 76) Lao, L. Effects of Chinese Herbs on Inflammatory Hyperalgesia and Edema in Rats, Building Bridges of Integration for TCM, Traditional Chinese Medicine World Foundation, East Rutherford, New Jersey, (October 9-12, 2003) 77) Lao, L. Effects of Electroacupuncture in Combinations with Morphine or Indomethacin to Synergistically or Additively Alleviate Inflammatory Pain in Rats, NIH National Institute of Drug Abuse, Molecular Neurobiology Branch, Baltimore, Maryland (August 2003) 78) Lao, L. Can a Western Ruler Measure Eastern Distances? Opportunities and Challenges in TCM Research, Building Bridges of Integration for TCM, Traditional Chinese Medicine World Foundation, East Rutherford, New Jersey, (October 9-12, 2003) 79) Lao, L. Acupuncture/TCM for Inflammatory Pain, Building Bridges of Integration for TCM, Traditional Chinese Medicine World Foundation, East Rutherford, New Jersey, (October 9-12, 2003) 80) Lao, L. Chinese herb attenuates hyperalgesia and edema in rats with persistent inflammation, a comparison between boswellia carterii and modified huo-luo-xiao-ling-dan. Society for Acupuncture Research 10th Annual Symposium. Cambridge, MA. (November 15-16, 2003) 81) Lao, L. Acupuncture and TCM clinical research methodology (Invited speaker), Shanghai University of Traditional Chinese Medicine, Shanghai, China (November, 28, 2003) 82) Lao, L. Brief history, development and current status of acupuncture/TCM in the US (Invited speaker), Shanghai University of Traditional Chinese Medicine, Shanghai, China (December, 1, 2003)

83) Lao, L. A Western ruler and Eastern distances: opportunities and challenges in TCM/acupuncture research (Invited speaker), Shanghai University of Traditional Chinese Medicine, Shanghai, China (December, 2, 2003)

2004 84) Lao, L. Clinical Trials and Challenges of Acupuncture Therapy for Pain Disorders (Invited speaker), Traditional Chinese Medicine Association-Alumni (TCMA), Mount Sinai Hospital, New York City, NY (January 4, 2004) 85) Lao, L. Nutritional Cantonese Soups: healthy, delicious, yet easy to cook. Howard County Chinese School (HCCS), Ellicott City, MD (February, 2004) 86) Lao, L. Diffusion of Traditional Chinese Medicine in the Western Medical View. Chinese Med Panel in Chinese American Intercollegiate Conference (CAIC), Duke University, Durham, NC (April, 2004) 87) Lao, L. Electrical Acupuncture: Clinical Applications. Workshop in 2004 Symposium: Medical Acupuncture in the new millennium: integrating science with tradition, the American Academy of Medical Acupuncture, Chicago, Illinois (April, 2004) 88) Lao, L. To Provide Electro Acupuncture Perspective to Review of Clinical Vignettes. Plenary Expert Panel in 2004 Symposium: Medical Acupuncture in the new millennium: integrating science with trad ition, the American Academy of Medical Acupuncture, Chicago, Illinois (April, 2004) 89) Lao, L. Electrical Acupuncture: Basic Research and Clinical Implications. Plenary Session in 2004 Symposium: Medical Acupuncture in the new millennium: integrating science with tradition, the American Academy of Medical Acupuncture, Chicago, Illinois (April, 2004) 90) Lao, L. Acupuncture Seminar: Introduction. Lunch-time seminar sponsored by UMB School of Medicine Students Associations CAO, APSA, and AMSA, Baltimore, Maryland (April, 2004) 91) Lao, L. Patent Herbs Used in Neurological Disorders (I & 2). Seminar Series, Maryland Academy of TCM, Adelphi, MD (May & June, 2004) 92) Lao, L. Acupuncture and TCM clinical research methodology Workshop, Shanghai University of Traditional Chinese Medicine, Shanghai, China (June 28-29, 2004) 93) Lao, L. Design of Acupuncture/TCM Clinical Trials: Opportunities and Challenges in TCM Research. Evidence based Chinese medicine Forum, International Society for Chinese Medicine (ISCM), Macao, China (July 5-7, 2004) 94) Lao, L. Evidence-based Medicine: Cochrane Collaboration in CAM. Evidence based Chinese medicin e Forum, International Society for Chinese Medicine (ISCM), Macao, China (July 5-7, 2004) 95) L ao, L. Patent Herbs Used in Ear, Nose & Throat Disorders (I & 2). Seminar Series, Maryland Academy of TCM, Adelphi, MD (September, 2004) 96) Lao, L. Electrical Acupuncture: Basic Research and Clinical Applications. CME Seminar, Maryland Society of Medical Acupuncture, Columbia, MD (September, 2004) 97) Lao, L. Mechanisms of electroacupuncture anti-hyperalgesia in peripheral inflammation: opioid receptor involvement. Society for Acupuncture Research 11th Annual Symposium. San Francisco, CA. (October, 2004) 98) Lao, L., The Validation of a Newly Designed Placebo Moxibustion Device: A randomized controlled trial. Society for Acupuncture Research 11th Annual Symposium. San Francisco, CA. (October, 1-3, 2004) 99) Lao, L. Is there a Scientific Basis for TCM? Building Bridges of Integration for TCM, Traditional Chinese Medicine World Foundation, East Rutherford, New Jersey, (October 7-10, 2004)

100) Lao, L. Traditional Chinese Medicine for Inflammatory Pain. Building Bridges of Integration for TCM, Traditional Chinese Medicine World Foundation, East Rutherford, New Jersey, (October 7-10, 2004) nd 101) Lao, L. Standard TCM Curriculum Requirements in the U.S. The 2 International Symposium on Traditional Chinese Medicine Education, Shanghai, China (November 2-3, 2004) 102) Lao, L. Safe Practices, Patient & Staff Education -- Acupuncture in Oncology Practice and Research, Society for Integrative Oncology First International Conference, Times Square, New York, NY (November 17-19, 2004)

2005 103) Lao, L. , Manheimer E, and Berman B. Systematic Reviews of Chinese Medicine, Internat ional Society of Chinese Medicine conference: Chinese Medicine for the Prevention and Treatment of Contemporary Diseases: An Evidence-based Approach, Macao, China (April 3, 2005) 104) Lao L. Effect of Chinese herbs on persistent inflammation in rats, International Society of Chinese Medicine conference: Chinese Medicine for the Prevention and Treatment of Contemporary Diseases: An Evidence-based Approach, Macao, China (April 3, 2005) 105) Lao, L. How to write a scientific paper on TCM research? Shanghai University of Traditional Chinese Medicine, Shanghai, China (April, 2005). 106) Lao, L. How to design a clinical trial of TCM research? Shu Guang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China (April, 2005). 107) Lao, L. Demonstration of Electro-Acupuncture; Harvard Continuing Medical Education Course, Structural Acupuncture for Physicians, Harvard Medical School, Cambridge, Massachusetts (April 21, 2005) 108) Lao, L. Scientific paper: Electro-Acupuncture; Harvard Continuing Medical Education Course, Structural Acupuncture for Physicians, Harvard Medical School, Cambridge, Massachusetts (April 21, 2005) 109) Lao, L. Is there scientific basis for TCM? -- challenges and strategies for TCM research, Australian Acupuncture & Chinese Medicine Annual Conference, Melbourne, Australia (May 15, 2005) 110) Lao, L. Effect of acupuncture on osteoarthritis, Australian Acupuncture & Chinese Medicine Annual Conference, Melbourne, Australia (May 14, 2005) 111) Lao, L. Acupuncture Research methodology, Tri-State College of Acupuncture Faculty Develop ment Course, New York City, NY (June 18, 2005) 112) Lao, L. Building bridges between scientific research and clinical practice – challenges and strategies for TCM research; Building Bridges of Integration for TCM, Traditional Chinese Medicine World Foundation, East Rutherford, New Jersey, (October 8, 2005). 113) L ao, L. Effectiveness of acupuncture as adjunctive therapy in osteoarthritis of the knee: a randomized trial Building Bridges of Integration for TCM, Traditional Chinese Medicine World Foundation, East Rutherford, New Jersey, (October 8, 2005). 114) Lao, L. Acupuncture in MS, Multiple Sclerosis: Advances in Management, Baltimore, MD (October 15, 2005) 115) Lao, L. Alternative Medicine Approaches to MS, Multiple Sclerosis: Advances in Management, Baltimore, MD (October 15, 2005) 116) Lao, L. Effect of acupuncture on osteoarthritis- a phase III, ramdomized, placebo-controlled clinical trial. Society for Acupuncture Research 12th Annual Symposium. Albuquerque, NM. (October 23, 2005) 117) Lao, L. Invited panelist. Neurobiological Correlates of Acupuncture. NCCAM, NIH, Bethesda, MD (Nov ember 18, 2005)

118) Lao, L. PAIN & ANALGESIA – III: Acupuncture and Chiropractic. Pathophysiology & Therapeutics, 1 (MSPR 521). UMB, Baltimore, MD (December 2, 2005) 119) Lao, L. Acupuncture in Primary Care. Core Lecture, Dept. Family Medicine, UMB, Baltimore, MD (Dec ember 21, 2005)

2006 120) L ao, L. Acupuncture and TCM History, Evidence-based Practice and Safety. CAM Course, Johns Hopkins University Medical School, Baltimore, MD (February 15, 2006) 121) Lao, L. Acupuncture History, Safety and Research. CAM Elective Course, University of Maryland Baltimore School of Medicine, Baltimore, MD (March 2, 2006) 122) Lao, L. Traditional Chinese Medicine (TCM) -- an introduction. CAM Elective Course, University of Maryland Baltimore School of Medicine, Baltimore, MD (March 9, 2006) 123) L ao, L. Acupuncture and CAM - History, Evidence-based Practice and Safety. Course PHMY 595, University of Maryland Baltimore School of Pharmacy, Baltimore, MD (March 16, 2006) 124) Lao, L. The Effect of Traditional Chinese Medicine on Arthritis. Grand Rounds, Chester River Hospital, Chestertown, MD, (March 22, 2006) 125) Lao, L. International Research Collaboration – University of Maryland Experience. Traditional Chinese Medicine (TCM) and Cancer Research: Fostering Collaborations; Advancing the Science, NCI, NIH, Bethesda, MD, (April 12, 2006) 126) Lao, L. Effect of Acupuncture on Pain – Clinical Trials. 25th American Pain Society’s Annual Scientific Meeting, San Antonio, TX, (May 4, 2006) 127) Lao, L. Sham Acupuncture Control – What do we learn from animal studies. North American Research Conference On Complementary and Integrative Medicine, Edmonton, Canada, (May 25, 2006) th 128) Lao, L. Acupuncture: A Therapeutic Approach to Chronic Pain. The 14 Annual Congress on Women ’s Health, Hilton Head Island, South Carolina, (June 4, 2006) 129) L ao, L. Workshop on Clinical Research Methodology in TCM. Korea Institute of Oriental Medicine, Daejeon, Korea (June 17-18, 2006) 130) Lao, L. Acupuncture in Primary Care. Grand Round, Frederick Memorial Hospital, Frederick, MD (June 23, 2006) 131) Lao, L. Arthritis and TCM. Traditional Chinese Medicine Association & Alumni (TCMAA), New York City, NY (June 25, 2006) 132) Lao, L. Panelist, Acupuncture Research Workshop Foundation for Traditional Chinese Medicin e, York, United Kingdom (July 5-8, 2006) 133) Lao, L. Clinical Researches on Traditional Chinese Medicine: Challenges and Strategies. Shanghai University of Traditional Chinese Medicine, Shanghai, China (Sept. 13, 2006). 134) Lao, L. Use of Animal Models to Investigate the Effects of Acupuncture on Pain (I & II). International Training Course, Fudan University, Shanghai, China (Sept. 22, 2006). 135) Lao, L. Methodological quality of RCTs. Seminar on Systematic Review/Meta-Analysis Methodology, Beijing University of Chinese Medicine, Beijing, China (Sept. 25-29, 2006). 136) Lao, L. Effectiveness of Acupuncture as Adjunctive Therapy in Osteoarthritis of the Knee: A Randomized Trial. The International Conference of Oriental Medicine, Kyung Hee University, Seoul, Korea (Sept. 28, 2006) 137) Lao, L. Controversies in Acupuncture Research: Selection of Controls and Outcome Measures. Building Bridges of Integration for TCM, Traditional Chinese Medicine World Foundation, East Rutherford, New Jersey (October 7, 2006). 138) Lao, L. Acupuncture and Arthritis - Evidence-Based Medicine. Integrative Health Options conference, New Jersey Medical School, Newark, New Jersey (October 20, 2006) 139) Lao, L. Acupuncture in Primary Care. Core Lecture, Dept. of Family & Community Medicine, UMB, Baltimore, MD (November 22, 2006) 51

140) Lao, L. Nociception, Pain And Analgesia: Integrative Medicine and Pain Management. Course # DBMS 642, Department of Biomedical Sciences, Dental School, UMB, Baltimore, MD (November 29, 2006) 141) Lao, L. PAIN & ANALGESIA – III: Acupuncture and Chiropractic. Pathophysiology & Therapeutics, 1 (MSPR 521). UMB, Baltimore, MD (December 1, 2006)

2007 142) L ao, L. Acupuncture & Chinese Medicine - History, Evidence-based Practice and Safety. Course PHMY 595, University of Maryland Baltimore School of Pharmacy, Baltimore, MD (March 29, 2007) 143) Lao, L. Acupuncture & Pain Management, Department of Physiology and Biophysics, School of Medic ine, Georgetown University, Washington DC (April 2, 2007) 144) Lao, L. Evidence Based TCM Practice: -- Challenges and Opportunities. International TCM Congress. Vienna, Australia ( September 28, 2007) 145) Lao, L. Chinese Herbal Soup Recipes for Health. TCM Congress - Tao of Jing. Vienna, Austria (September 28, 2007) 146) Lao, L. Applications of Electroacupuncture. International TCM Congress. Vienna, Australia (September 28, 2007) 147) Lao, L. “West meets the East” - The Role of Acupuncture and Chinese Medicine in Patient Care. Abbott Northwestern Hospital. (October 5, 2007) 148) Lao, L. Invited Keynote Speaker. Ancient Acupuncture and Modern Evidence Based Medicine -- Challenges and Opportunities. International Conference on Automation Science and Technology. Chinese Academy of Sciences. Beijing, China. (October 19, 2007) 149) Lao, L. Invited Keynote Speaker. Acupuncture in Evidence Based Medicine. The 20th Anniversary of World Federation of Acupuncture- Mosibustion Societies (WFAS) and International Acupuncture Congress. Beijing, China. (October 20, 2007) th 150) Lao, L. Functions and Specificities of Acupuncture Points. The 20 Anniversary of World Federation of Acupuncture- Mosibustion Societies (WFAS) and International Acupuncture Congress. Beijing, China. (October 21, 2007) 151) Lao, L. TCM Education in US. The 20th Anniversary of World Federation of Acupuncture-Moxibustion Societies (WFAS) and International Acupuncture Congress. Beijing, China. ( October 21, 2007) 152) Lao, L. Electroacupuncture (EA) Mechanisms on Persistent Inflammation and Pain. Society for Acup uncture Research 2007 Annual Conference. Baltimore, Maryland. (November 10, 2007) 153) Lao, L. Acupuncture Clinical Studies and Evidence Based Medicine -- An Update. International Symposium on Acupuncture Research. China Academy of Chinese Medical Sciences. Beijing, China (November 20, 2007) 154) Lao, L. Acupuncture Clinical Studies and Evidence Based Medicine -- An Update. Shanghai University of Traditional Chinese Medicine. Shanghai, China. (November 22, 2007) 155) Lao, L. Clinical Researches on Traditional Chinese Medicine: -- Challenges and Strategies. Chang Zheng Hospital. Shanghai, China ( November 23, 2007)

2008 156) Lao, L. Acupuncture and Parkinson’s’ disease. Kernan Parkinson’s supporting group (March 11, 2008) rd 157) L ao, L. Acupuncture in Primary Care--History, Evidence-based Practice and Safety. 3 Year Medical Student Clerkship Lecture, Dept. of Family & Community Medicine, UMB, Baltimore, MD (Once a month from January through December, 2008)

158) Lao, L. Acupuncture & Chinese Medicine - History, Evidence-based Practice and Safety. Course PHMY 595, University of Maryland Baltimore School of Pharmacy, Baltimore, MD (March 13, 2008) 159) L ao, L. Clinical Research Design I (24 hours credit). Course #DA711, American College of Traditional Chinese Medicine, San Francisco, CA (March 27-31, 2008) 160) Lao, L. Acupuncture Code of Ethics. Seminar series, Maryland Academy of TCM, Bethesda, MD (April 20, 2008) 161) Lao, L. Medical Qigong. Maryland Academy of TCM, Bethesda, MD (April 27, 2008) 162) Lao, L. Promoting Traditional Chinese Medicine in the United States and the Western World: Challenges and Strategies. State Administration of TCM, Beijing, China (May 5, 2008) 163) L ao, L. TCM Clinical Research and Acceptance in USA: Challenges and Difficulties. Guangzhou University of TCM, Guangzhou, China (May 6, 2008) 164) Lao, L. Promoting Clinical Research on Traditional Chinese Medicine: Strategies and Methodology. Guangzhou University of TCM, Guangzhou, China (May 8, 2008) 165) Lao, L. Clinical Efficacy of Acupuncture: Challenges and Methodology. CCTN-DCNBR/NIDA Joint Workshop: Pain, Stress, and Healthier Life Choices with an Eastern Approach, NIDA/NIH, Rockville, Maryland (May 20, 2008) 166) Lao, L. Acupuncture in Primary Care--History, Evidence-based Practice and Safety. Core Lecture for Residents, Dept. of Family & Community Medicine, UMB, Baltimore, MD (July 9, 2008) 167) Lao, L. Treatment for inflammatory pain and related diseases -- Clinical applications of electroacupuncture (EA). American Association of Acupuncture & Oriental Medicine (AAAOM) Conference, Chicago, IL (Oct. 18, 2008) 168) Lao, L. Acupuncture Activates endogenous resilience to inflammatory pain. Beijing Joint Conference of Physiological Sciences, Beijing, China (Oct. 21, 2008) 169) Lao, L. Clinical Research on Acupuncture and TCM: Research Design, Grant Writing, and Manuscript Preparation. Changhai Hospital. Shanghai, China (October 30, 2008) 170) L ao, L. Clinical Research on TCM: Challenges, Research Design, and Manuscript Preparation. Shanghai University of TCM, Shanghai, China (November 5, 2008) 171) Lao, L. TCM Clinical Research and Acceptance in USA - Challenges and Difficulties. World Health Organization - State Administration of TCM Workshop, Guangzhou University of TCM, Guangzhou, China (Nov. 11, 2008) 172) Lao, L. Clinical Research Design I (24 hours credits). Course #DA711, American College of Tradition al Chinese Medicine, San Francisco, CA (Dec 12-14, 2008)

2009 173) Lao, L. Evidence-Based Medicine in Traditional Chinese Medicine. The National Center for Complementary and Alternative Medicine (NCCAM), Education Series on Complementary and Integrative Medicine, NIH, Bethesda, MD (Jan 5, 2009) rd 174) Lao, L. Acupuncture in Primary Care--History, Evidence-based Practice and Safety. 3 Year Medical Student Clerkship Monthly Lecture, Dept. of Family & Community Medicine, UM B, Baltimore, MD (Once a month from January through December, 2009) 175) L ao, L. Acupuncture History, Safety and Research. CAM Elective Course, Center for Integrative Medicine, University of Maryland Baltimore School of Medicine, Baltimore, MD ( February 11, 2009) 176) Lao, L. PAIN & ANALGESIA – III: Acupuncture for Chronic Pain. Pathophysiology & Therapeutics, 1 (MSPR 521). UMB, Baltimore, MD (February 17, 2009) 177) L ao, L. Traditional Chinese Medicine (TCM) -- an introduction. CAM Elective Course, Center for Integ rative Medicine, University of Maryland Baltimore School of Medicine, Baltimore, MD (February 25, 2009) 53

178) Lao, L. Invited Presentation: Clinical Research on Traditional Chinese Medicine: Methodological Problems and Challenges. WHO working group meeting on clinical studies, Milan, Italy (March 30, 2009) 179) Lao, L. Acupuncture & Chinese Medicine - History, Evidence-based Practice and Safety. Course PHMY 595, University of Maryland Baltimore School of Pharmacy, Baltimore, MD (April 16, 2009) 180) Lao, L. TCM Treatment of Arthritis and Related Disorders-- Research Update. Seminar series, Maryland Academy of TCM, Bethesda, MD (April 19, 2009) 181) Lao, L. and Che, CT. Safety Profile and Biological Property of a Chinese Herbal Formula. North American Research Conference on Complementary and Integrative Medicine (NARCCIM). Minneapolis, Minnesota, (May 13, 2009) 182) Lao, L. (co-chair of the symposium) Acupuncture Activates Endogenous Resilience to Inflammatory Pain. North American Research Conference on Complementary and Integrative Medicine (NARCCIM). Minneapolis, Minnesota, (May 14, 2009) 183) Lao, L. Acupuncture in Primary Care--History, Evidence-based Practice and Safety. Core Lecture for Residents, Dept. of Family & Community Medicine, UMB, Baltimore, MD (May 20, 2009) 184) Lao, L. TCM Clinical Research Design and Development in the West-- A Workshop. Third Annual International Symposium on Evaluation of Clinical Trial Methodologies, Applications, Design, and Frontiers of Data Analysis-- New Methodological Developments in Traditional Chinese Medicine Research. Beijing, China, (June 26, 2009) 185) Lao, L. Invited keynote speech: Key Issues and Strategies in TCM Research. Third Annual International Symposium on Evaluation of Clinical Trial Methodologies, Applications, Design, and Frontiers of Data Analysis-- New Methodological Developments in Traditional Chinese Medicine Research. Beijing, China, (June 27, 2009) 186) Lao, L. Traditional Chinese Medicine in Primary Care--History, Evidence-based Practice and Safety. Core Lecture for Residents, Dept. of Family & Community Medicine, UMB, Baltimore, MD (July 29, 2009) 187) Lao, L. Acupuncture and Pain Management. Grand Round. Kernan Hospital, Baltimore, MD (Aug. 12, 2009) 188) L ao, L. Acupuncture History, Safety and Research. CAM Elective Course, Center for Integrative Medicine, University of Maryland Baltimore School of Medicine, Baltimore, MD (Oct. 28, 2009) 189) Lao, L. Traditional Chinese Medicine (TCM) -- an introduction. CAM Elective Course, Center for Integrative Medicine, University of Maryland Baltimore School of Medicine, Baltimore, MD (Nov. 2, 2009) 190) Lao, L. A discussion/demonstration on acupuncture. The Complementary and Integrative Medicine Student Interest Group, University of Maryland School of medicine, Baltimore, MD (November 4, 2009) 191) Lao, L. Key Issues and Strategies in TCM Research. International Conference and Exposition on Tradi tional Medicine 2009. Guangzhou, China (Nov. 10, 2009) 192) Lao, L. Complementary and alternative medicine-a workshop. Asian Pacific American Medical Student Association, Johns Hopkins School of Medicine, Baltimore, MD (December 9, 2009) 193) Lao, L. Clinical Research Design I (24 hours credits). Course #DA711, American College of Traditional Chinese Medicine, San Francisco, CA (Dec 11-13, 2009)

2010

rd 194) L ao, L. Acupuncture in Primary Care--History, Evidence-based Practice and Safety. 3 Year Medical Student Clerkship Monthly Lecture, Dept. of Family & Community Medicine, UMB, Baltimore, MD (Once a month from January through December, 2010) th 195) L ao, L. Acupuncture History, Safety and Research. 4 Year CAM Elective Course, Center for Integrative Medicine, University of Maryland Baltimore School of Medicine, Baltimore, MD (Feb. 4 & Oct. 27, 2010) 196) Lao, L. Acupuncture & Chinese Medicine - History, Evidence-based Practice and Safety. Course PHMY 595, University of Maryland Baltimore School of Pharmacy, Baltimore, MD (Feb. 12, 2010 ) th 197) Lao, L. Traditional Chinese Medicine (TCM) -- an introduction. 4 Year CAM Elective Course, Center for Integrative Medicine, University of Maryland Baltimore School of Medicine, Baltimore, MD (Feb. 17 & Nov. 3, 2010) 198) Lao, L. PAIN & ANALGESIA – III: Acupuncture for Chronic Pain. Pathophysiology & Therapeutics, 1 (MSPR 521). UMB, Baltimore, MD (February 24, 2010) 199) Lao, L. Involvement of supraspinal opioid receptors in electroacupuncture-produced anti-hyperalgesia in rats with peripheral inflammation. Society for Acupuncture Research 2010 Annual Conference. Chapel Hill, North Carolina, (March 20, 2010) 200) Lao, L. Acupuncture in Primary Care. Grand Rounds, Department of Family & Community Medicin e , University of Maryland School of Medicine, Baltimore, MD, (Aug. 25, 2010) 201) L ao, L. Auricular Acupuncture. Resident Core Lecture, Department of Family & Community Medicine, University of Maryland School of Medicine, Baltimore, MD, (Aug. 25, 2010) 202) Lao, L. Key Issues and Strategies in TCM Research. Long Hua Hospital, Shanghai, China (Sept. 9, 2010) 203) Lao, L. Challenges and Strategies on Acupuncture Clinical Trial Design -- a panel discussion. Congress of the Medical Acupuncture College of São Paulo (CMASP), São Paulo, Brazil (October 14, 2010) 204) Lao, L. Mechanism of acupuncture on inflammation and persistent pain. Congress of the Medical Acupuncture College of São Paulo (CMASP), São Paulo, Brazil (October 14, 2010) 205) Lao, L. Acupuncture treatment for knee pain. Congress of the Medical Acupuncture College of São Paulo (CMASP), São Paulo, Brazil (October 15, 2010) 206) Lao, L. Electroacupuncture: clinical application – a workshop. Congress of the Medical Acupuncture College of São Paulo (CMASP), São Paulo, Brazil (October 16, 2010) 207) Lao, L. The Effect of Acupuncture on Postoperative Oral Surgical Pain: a Placebo-Controlled Clinical Trial. Congress of the Medical Acupuncture College of São Paulo (CMASP), São Paulo, Brazil (October 17, 2010) 208) Lao, L. Auricular Acupuncture-A Workshop. Congress of the Medical Acupuncture College of São Paulo (CMASP), São Paulo, Brazil (October 17, 2010) 209) Lao. L. Integrative Medicine an Emerging Model In Clinical Practice and University Curriculum. Seminar. Universidade Federal de Santa Catarina. (UFSC), Florianopolis, Brazil (October 20, 2010) th 210) Lao, L. Auricular Acupuncture. 4 Year CAM Elective Course, Center for Integrative Medicine, University of Maryland Baltimore School of Medicine, Baltimore, MD (Nov. 1, 2010) 211) Lao, L. Keynote Speech: Acupuncture Research –An Update. World Federation of Acupuncture and Moxibustion Societies (WFAS) 2010 International Acupuncture Conference in US. San Francisco, CA, (November 6, 2010) 212) Lao, L. Keynote Speech: Acupuncture Research –An Update. World Federation of Acupuncture and Moxibustion Societies (WFAS) 2010 International Acupuncture Conference in US. San Francisco, CA, (November 6, 2010)

213) Lao, L. Mechanism of acupuncture on inflammation and persistent pain. World Federation of Acupuncture and Moxibustion Societies (WFAS) 2010 International Acupuncture Conference in US. San Francisco, CA (Nov. 6, 2010) 214) Lao, L. Acupuncture in Me dicine. Lunch Seminar, Harbor Hospital, Baltimore, MD, (November 17, 2010) rd 215) Lao, L. Mechanism of acupuncture on inflammation and persistent pain. The 3 International Conference on the Modernization of Traditional Chinese Medicine (TCM). Chengdu, China (November 25, 2010)

2011 rd 216) L ao, L. Acupuncture in Primary Care--History, Evidence-based Practice and Safety. 3 Year Medical Student Clerkship Monthly Lecture, Dept. of Family & Community Medicine, UM B, Baltimore, MD (Once a month from January through December, 2011) 217) Lao, L. Plenary Speaker: Mechanisms of Acupuncture on Irritable Bowel Syndrome. Hong Kong International Acupuncture Conference. Hong Kong, China (Jan. 14, 2011) 218) Lao, L. Clinical Research in TCM and Acupuncture (8 hours credits). Course DRE 803-806, Research Methodology IV. Five Branches University, San Jose, CA (Jan 30, 2011) 219) Berman, B & Lao, L. Mechanisms of acupuncture modulation in acute pain (human research). DOD – NIH Workshop on Acupuncture for Treatment of Acute Pain. Bethesda, MD (Feb 2, 2011) 220) Lao, L. Mechanisms of Acupuncture on Irritable Bowel Syndrome. International conference on TCM and Functional Gastrointestinal Disorders (FGID) and Inflammatory Bowel Disease (IBD): East Meets West. Hong Kong, China (Feb. 17, 2011) 221) Lao, L. Research Design on TCM Clinical Trials. Seminar, Shanghai Traditional Chinese Medicine Hospital, Shanghai, China (Feb. 22, 2011) 222) Lao, L. Acupuncture in Chinese Medicine. Lunch ‘n Learn Workshops, Work/Life Strategies Department in HR, University of Maryland Baltimore, Baltimore, MD, (March 8, 2011) 223) Lao, L. Tai Chi. Lunch ‘n Learn Workshops, Work/Life Strategies Department in HR, University of Maryland Baltimore, Baltimore, MD, (March 23, 2011) 224) Lao, L. From Basic Science Studies to Clinical Trials – What Recent Acupuncture Research Tells Us. 2011 Symposium of the American Academy of Medical Acupuncture, San Diego, CA (April, 1, 2011) 225) Lao, L. Traditional Chinese Medicine. Resident Core Lecture, Department of Family & Commu nity Medicine, University of Maryland School of Medicine, Baltimore, MD, (May 4, 2011) 226) Lao, L. Plenary Speaker: From Basic Science Studies to Clinical Trials – What Recent Acupuncture Research Tells Us. 2011 Annual Conference of American Association of Acupuncture and Oriental Medicine (AAAOM), Baltimore, MD (May 13, 2011) 227) Lao, L. Invited Panelist. Roundtable Discussion. From Basic Science Studies to Clinical Trials. 2011 Forum on Scientific Explanation on Tradition Chinese Medicine and Acupuncture, Nan Tong, Jiang Su Province, China, (June 20, 2011) 228) Lao, L. Invited Speaker. Complementary and Alternative Medicine and Cancer. Traditional Chinese Medicine and Modern Technology for Cancer Prevention and Treatment. Shanghai Graduate Student Summer School. Shanghai U. of TCM affiliated Longhua Hospital, Shanghai, China (July 18, 2011) 229) Lao, L. Invited Panelist. Roundtable Discussion. Interdisciplinary Consensus Workshop on the development of an Effectiveness Guidance Document for Acupuncture Research. Santa Fe, NM (July 24, 2011) 230) Lao, L. Invited Panelist. Roundtable Discussion 1: How can differences in clinical patient characteristics of pain and treatment responses better inform clinical medicine and 56

prospective research? Pathways Toward Evidence-Based, Personalized Analgesic Medication. National Institute on Drug Abuse (NIDA), Bethesda, MD (September 14, 2011) 231) Lao, L. Clinical Research Design I (20 hours). Doctoral Program (DAOM), Course #DA715, America n College of Traditional Chinese Medicine, San Francisco, CA (September 9-11, 2011) 232) Lao, L. Invited Speaker. Acupuncture Code of Ethics and Safety. Seminar (CEUs) at Virginia Institute of Traditional Chinese Medicine, VA (September 25, 2011) 233) Lao, L. Invited Speaker. Acupuncture in Inflammatory Disease: Use and Mechanisms, International Scientific Acupuncture and Meridian Symposium, Irvine, CA, USA (October 7, 2011) 234) Lao, L. Invited Speaker. Development and Status of TCM/Acupuncture Education in the USA. Second World Education Congress of Chinese Medicine, Beijing, China (October 29, 2011) 235) Lao, L. Invited Speaker. From Basic Science Studies to Clinical Trials – What Recent Acupuncture Research Tells Us Forum of Distinguished Professor Series, Beijing University of Chinese Medicine, Beijing, China (November 25, 2011) 236) Lao, L. Invited Speaker. From Basic Science Studies to Clinical Trials – What Recent Acupuncture Research Tells Us. Harbor Hospital, Health Science Library Baltimore, MD, (December 5, 2011)

2012 rd 237) Lao, L. Acupuncture in Primary Care--History, Evidence-based Practice and Safety. 3 Year Medical Student Clerkship Monthly Lecture, Dept. of Family & Community Medicine, UMB, Baltimore, MD (Once a month from January through December, 2012) 238) Lao, L. Invited Panelist. Roundtable Discussion: Manual Acupuncture vs Electroacupuncture. Society for Acupuncture Research (SAR) Think Tank Workshop. Boston, MA, (January 19-22, 2012) th 239) Lao, L. Acupuncture History, Safety and Research. 4 Year CAM Elective Course, Center for Integrative Medicine, University of Maryland Baltimore School of Medicine, Baltimore, MD (Feb. 2, 2012) th 240) Lao, L. Auricular Acupuncture: Lecture and Workshop. 4 Year CAM Elective Course, Center for Integrative Medicine, University of Maryland Baltimore School of Medicine, Baltimore, MD (Feb. 6, 2012) th 241) Lao, L. Traditional Chinese Medicine (TCM) -- an introduction. 4 Year CAM Elective Course, Center for Integrative Medicine, University of Maryland Baltimore School of Medicine, Baltimore, MD (Feb. 8, 2012) 242) Lao, L. Clinical Evidence of Acupuncture on Treating Low Back Pain. American Academy of Pain Medicine. Palm Spring, CA, (February 25, 2012) 243) Lao, L. East Meets West. Health & Wellness Conference. Center for Integrative Medicine, University of Maryland School of Medicine, Baltimore, MD, (April 14, 2012) 244) Lao, L. Invited Speaker. Development and Status of Acupuncture Needling Techniques in the West. W orld Federation of Chinese Medicine Societies (WFCMS). Changchun, China (June 23, 2012) 245) Lao, L. Instructor. Clean Needle Techniques (CNT) Course. TAI-Sophia, Laura, MD (July 8, 2012) 246) Lao, L. Invited Speaker. The Complexities Inherent in Placebo-Controlled Acupuncture Studies 2012 International Symposium on Theory and Evidence in Acupuncture. Singapore (August 21, 2012) 247) Lao, L. Invited Speaker. Clinical Research on Acupuncture and TCM: Research Design, Grant Writing, and Manuscript Preparation. Xinjiang Medical University Affiliated Second Hospital. Wulumuqi, Xinjiang, China, (August 23, 2012) 57

248) Lao, L. Invited Speaker. Clinical Research on Acupuncture and TCM: Research Design, Grant Writing, and Manuscript Preparation. Xinjiang People’s Hospital, Wulumuqi, Xinjiang, China, (August 25, 2012) 249) Lao, L. Invited Speaker. What elements are necessary for a competitive research grant proposal? Public workshop about the grant proposal writing. LKS Faculty of Medicine, Hong Kong University, Hong Kong, (August 30, 2012) 250) Lao, L. Invited Speaker. From pre-clinical studies to clinical trials - Acupuncture research in the Center for Integrative Medicine at the University of Maryland Public seminar on researches. LKS Faculty of Medicine, Hong Kong University, Hong Kong, (August 31, 2012) 251) Lao, L. Acupuncture in Primary Care. Wellness Hub-Wellness Grand Round, University of Maryland Baltimore, Baltimore, MD (September 20, 2012) 252) Lao, L. Invited Speaker. Development and Status of TCM/Acupuncture Education in the USA. Second World Education Congress of Chinese Medicine, Beijing, China (October 29, 2011) th 253) Lao, L. Acupuncture History, Safety and Research. 4 Year CAM Elective Course, Center for Integrative Medicine, University of Maryland Baltimore School of Medicine, Baltimore, MD (September 27, 2012) th 254) Lao, L. Auricular Acupuncture: Lecture and Workshop. 4 Year CAM Elective Course, Center for Integrative Medicine, University of Maryland Baltimore School of Medicine, Baltimore, MD (October 2, 2012) th 255) Lao, L. Traditional Chinese Medicine (TCM) -- an introduction. 4 Year CAM Elective Course, Center for Integrative Medicine, University of Maryland Baltimore School of Medicine, Baltimore, MD (October 11, 2012) 256) Lao, L. Acupuncture Treatment of Musculoskeletal Pain -- Research Update. Seminar series, Maryland Academy of TCM, Bethesda, MD (October 14, 2012) 257) Lao, L. Acupuncture Research in West – An Update. Seminar of Oversea Distinguished Professo r. Shanghai University of Traditional Chinese Medicine (SUTCM), Shanghai, China (November 7, 2012) 258) Lao, L. Invited Speaker. Research on Acupuncture Needling Technique in the West. The 30th Anniversary of School of Acupuncture-Moxibustion and Tuina, BUCM & The 3rd International Symposium of Techniques of Acupuncture-Moxibustion and Tuina, Beijing, China (November 10, 2012)

2013 rd 259) Lao, L. Acupuncture in Primary Care--History, Evidence-based Practice and Safety. 3 Year Medical Student Clerkship Monthly Lecture, Dept. of Family & Community Medicine, UMB, Baltimore, MD (Fridays, once a month from January through Junee, 2013) th 260) Lao, L. Acupuncture History, Safety and Research. 4 Year CAM Elective Course, Center for Integrative Medicine, University of Maryland Baltimore School of Medicine, Baltimore, MD (Jan. 31, 2013) 261) Lao, L. Auricular Acupuncture and Traditional Chinese Medicine: Lecture and Workshop. 4th Year CA M Elective Course, Center for Integrative Medicine, University of Maryland Baltimore School of Medicine, Baltimore, MD (Feb. 5, 2013) 262) Lao, L. Electroacupuncture Inhibits Spinal p-CAMKII to Suppress Chemotherapy-induced Pain in Rats. Society for Acupuncture Research 2010 Annual Conference. Ann Arbor, Michigan, (April 20, 2013) 263) Lao, L. Topical Treatment With Tong-Luo-San-Jie Gel (TLSJ) Alleviates Bone Cancer Pain in Rats. Society for Acupuncture Research 2010 Annual Conference. Ann Arbor, Michigan, (April 20, 2013)

264) Lao, L. East Meets West: Treating Pain with Acupuncture. Health & Wellness Conference. Center for Integrative Medicine, University of Maryland School of Medicine, Baltimore, MD, (May 4, 2013) 265) Lao, L. State of the Art in Acupuncture Research: an Update. 2013 Symposium of the American Academy of Medical Acupuncture, Baltimore, Maryland, (May 5, 2013) 266) Lao, L. Invited Speaker. Acupuncture/TCM Research in the West-- status and impact. Xi`an Jiaotong University, Xi`an, China (July 8,2013) (Grant # R24 AT001293) 267) Lao, L. Invited Speaker. Latest Research and Development Trend in Chinese Medicine. Seminar on Research and Development of Chinese Medicines. Committee on Research and Development of Chinese Medicine, Hong Kong, China (September 5, 2013) 268) Lao, L. Invited Speaker. Acupuncture Clinical Trials: an update. The 4th International Confere nce on the Modernization of Traditional Chinese Medicin e (TCM), Chengdu, China (September 26, 2013) 269) Lao, L. Invited Speaker. From bench to bedside: Translational studies of acupuncture for inflammatory pain. Karolinska Institute, Stockholm, Sweden (October 6, 2013) 270) Lao, L. Invited Speaker. Acupuncture and Chinese Medicine Research in the West: Status, Impact and Development. World Federation for Acupuncture and Moxibustion Societies, WFAS, Sydney, Australia (November 3, 2013) 271) Lao, L. Invited Speaker. Development of Acupuncture Practice and Training in the USA. Chinese University of Hong Kong, Hong Kong (November 30, 2013) 272) Lao, L. Invited Speaker. TCM/Acupuncture Education and Research in the USA. The 3rd editor meeting and digitalization expert symposium, Beijing, China (December 7,2013)

2014 273) Lao, L. Invited Speaker. Traditional Therapy for Osteoarthritis – Current Evidence, Integrative Care for Osteoarthritis Symposium – East meets West, Prince of Wales Hospital, Hong Kong (January 11, 2014) 274) Lao, L. Invited Speaker. Development of TCM acupuncture overseas and HKU’s philosophy in training TCM talents. Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China (March 7, 2014) 275) Lao, L. Invited Speaker. Evidence-based medicine in TCM. Hong Kong Baptist University, Hong Kong (March 16, 2014) 276) Lao, L. Invited Speaker. Conference on “Understanding & Application of TCM in Enhancing Medical Health Against Emerging Environment Health in the Asia Pacific Region”, Mercer, Hong Kong (March 20, 2014) 277) Lao, L. Invited Speaker. Mechanisms of Acupuncture on Pain – An Overview. Asian Congress on Pain, Taiwan, China (March 28, 2014) 278) Lao, L. Invited Speaker. Acupuncture Clinical Trials on Pain – An Update. Asian Congress on Pain, Taiwan, China (March 29, 2014) 279) Lao, L. Invited Speaker. From Bench to Bedside: Translational Studies of Acupuncture for Inflammatory Pain. Asian 59

Congress on Pain, Taiwan, China (March 29, 2014)

2015 280) Lao, L. Invited Speaker. 中醫在美國的地位、現狀、行醫資格及在主流醫學的作用, 香港中醫學會中醫專業持續進修課程, 香港 (March 29, 2015) 281) Lao, L. Invited Speaker. Build-up of Chinese Medicine Hospital: China and Abroad Experience, Seminar on “Chinese Medicine Hospital in Hong Kong: Building Up Directions”, Hong Kong (March 15, 2015) 282) Lao, L. Invited Speaker. 2015首屆兩岸四地中醫藥循証高峰論壇, 北京 (June 5, 2015) 283) Lao, L. Invited Speaker. 針刺治療痛症的循證醫學進展, 第三屆國際中醫痛症研討會, 香港 (June 21, 2015) 284) Lao, L. Invited Speaker. 痛症的針刺及中醫藥治療學術會議, 深圳 (Sep 12, 2015) 285) Lao, L. Invited Speaker. 8th European Congress for Integrative Medicine (ECIM) Nordic Summit on Integrative Medicine and Global Health, Denmark (Sep 25, 2015) 286) Lao, L. Invited Speaker. iSAMS 2015 Conference (International Scientific Acupuncture and Meridian Symposium), New Zealand (Oct 2, 2015) 287) Lao, L. Invited Speaker. 2015 International Conference on the inaugural of International Consortium for Chinese Medicine and Cancer (ICCMC), Dalian (Oct 17, 2015) 288) Lao, L. Invited Speaker. 腫瘤的中醫藥防治和研究進展學術會議（2015）, 深圳 (Nov 14, 2015) 2 89) Lao, L. Invited Speaker. The 9th Pong Ding Yuen International Symposium on Traditional Chine se Medicine – Chinese Medicine for Mental Health: From Bedside to Bench, Hong Kong (Dec 5, 2015)

2016 290) Lao, L. Invited Speaker. International forum on the development of Hong Kong Chinese medicine hospital. HKBU, Hong Kong (12 March 2016). 291) Lao, L. Invited Speaker. The Symposium “Learning from Nature, learning from our Ancestors; from traditio n to evidence based medicines”. Leiden University, Netherlands (April 13-15, 2016). 292) Lao, L. Invited Speaker. Acupuncture on pain management ─ is there any Evidence? International Forum on Traditional Chinese Medicine. Longhua Hospital, Shanghai, China (May 26-29, 2016) 293) Lao, L. Invited Speaker. 2016 年中醫藥防治疼痛及相關性神經系統疾病高峰論壇, 香港大學 (June 5, 2016) 294) Lao, L. Invited Speaker. Conference on acupuncture for cancer symptom management, NIH Main Campus, Bethesda, Maryland (June 16-17, 2016) 295) Lao, L. Chairman. Joint Symposium of Big Data in Integrative Medicine Research, The Chinese University of Hong Kong (July 16, 2016) 296) Lao, L. Invited Speaker. Evidence-base medicine in acupuncture research: challenges and opp ortunities , The 15th

Meeting of the Consortium for Globalization of Chinese Medicine (CGCM), Academia Sinica in Taipei, Taiwan (August 22-26, 2016)

2017 300) Lao, L. Visiting Faculty. Integrative Medicine Week of UCLA. UCLA Center for East-West Medicine (CEWM), LA, USA. (Jul 14-16, 2017) 301) Lao, L. Invited Speaker. Virginia University of Oriental Medicine Weekend Engagement of Acupuncture and Oriental Medicine. Virginia University of Oriental Medicine, VA, USA. (Jul 28-30, 2017) 302) Lao, L. Invited expert. 2017 International Consortium for Chinese Medicine and Cancer (ICCM C). International Consortium for Chinese Medicine and Cancer, Guangzhou, China. (Aug 17, 2017) 303) Lao, L. Invited Speaker. 中医药研究学术交流, 江西中医药大学循证医学研究中心, Nanchang, Guangzhou (Sep 14-17, 2017). 304) Lao, L. Invited expert. 2017 National Certification Commission for Acupuncture and Oriental Medicine, Guangzhou NCCAOM Clean Needle Technique (CNT) courses. NCCAOM, Beijing, China. (Oct 10, 2017) 305) Lao, L. Invited Speaker. Development of Chinese Medicine in HKU-SZH-Sharing Experience, Chinese Medicine Hospital Experts Sharing Seminar, Hong Kong Hospital Authority, Hospital Authority Building, Hong Kong (Nov 11, 2017). 306) Lao, L. Panel Discussion Speaker. Chinese Medicine Hospital Experts Sharing Seminar, Hong Kong Hospital Authority, Hospital Authority Building, Hong Kong (Nov 11, 2017). 307) Lao, L. Invited Speaker. Current stages of acupuncture analgesia: evidence from clinic settings, Summary Report of the National Natural Science Foundation of China on interaction of acupuncture analgesia and placebo: evidence from pain sensitivity and effective connectivity analysis. Xi’an Jiaotong University, Xi’an China. (Nov 13-15, 2017). 308) Lao, L. Guest Expert. 中医针灸传承基地学术交流论坛. 澳门中医药学会, Dongguan, Guangdong, China. (Nov 24-26, 2017). 309) Lao, L. Invited Speaker. 世界针联第九届会员大会暨2017中国北京世界针灸学术大会. 世界针灸学会联合会、中国中医科学院和世界卫生组织. Beijing, China (Dec 1-4, 2017). 310) Lao, L. Invited Speaker. A Global View of TCM for Disease Prevention, 世界中聯體質研究專業委員會換屆大會暨第六屆學術年會,世界中聯體質研究專業委員會, Shenzhen Hospital Affiliated to Beijing University of TCM, Shenzhen, Guangzhou (Dec 4, 2017). 311) Lao, L. Invited Speaker. 2017世界首届针灸康养大会. 世界针灸联合会、中国中医科学院、 CCTV-7中国农业电影电视中心, Qujiang, China (Dec 5, 2017). 312) Lao, L. Panel Discussion Speaker. 中医学专业（针灸推拿5+3一体化方向）和全英语（针灸学）专业教学管理、课程设置专家咨询会. Shanghai University of Traditional Chinese Medicine, Shanghai, China. (Dec 22-24, 2017).

2018 313) Lao, L. Invited Speaker. 上海市中医医院科研基金撰写培训, 上海市中医医院, Shanghai, China (Feb 12-14, 2018). 314) Lao, L. Invited Speaker. 晨星文化中国人才计划, 浙江大学儒商与东亚文明研究中心, Hangzhou, China (Mar 30-Apr 1, 2018). 315) Lao, L. Invited Expert. DSMB Meeting for NSFC Project--clinical trial of CO2 laser moxibustion for knee osteoarthritis: A double-blind randomized controlled trial (National Natural Science Foundation of China (81320108028), Shanghai University of Traditional Chinese Medicine, Shanghai, China. (May 4-6, 2018)

316) Lao, L. A double-blind, randomized, two-dose trial of Chinese medicine, Tumor-Shrinking Decoction (TSD), in patients with symptomatic uterine fibroids, 2018 International Congress on Integrative Medicine and Health, Baltimore, Maryland, U.S.A (May 8-11, 2018). 317) Lao, L. Invited Speaker.國際針灸高峰論壇. Convention Hall, Hong Kong Convention and Exhibition Centre, Hong Kong, China. (May 17, 2018) 318) Lao, L. Invited Speaker. 2018 Beijing International Neurology and Acupuncture Seminar. Beijing Landmark Towers, Beijing, China. (June 30, 2018) 319) Lao, L. Invited Speaker. 針刺的轉換醫學: “無痛針刺”的臨床應用, 作用機理及循證醫學. Hong Kong International Summit of Chinese Medicine. Convention Hall, Hong Kong Convention and Exhibition Centre, Hong Kong, China. (August 05, 2018) 320) Lao, L. Challenges of Chinese Medicine Clinical Trials: How to interpret the data from “negative” R CTs? The 3rd International Symposium on Phytochemicals in Medicine and Food, Kunming, Yunnan, China. (August 25-30, 2018) 321) Lao, L. Efficacy and safety of acupuncture treatment on primary insomnia: a randomized controlled trial. The ICMART-iSAMS 2018 World Congress on Medical Acupuncture and Related Techniques, Munich, Germany. (September 07-09, 2018) 322) Lao, L. Efficacy and safety of acupuncture treatment on primary insomnia: a randomized controlled trial. The World Acupuncture Day, Paris, France. (November 15-17, 2018)

2019 323) Lao, L. Invited Speaker. Evidence-based medicine and mechanisms of action of acupuncture. University of Macau, Macau, China (Feb 15-16, 2019) 324) Lao, L. Invited Speaker. Chinese Medicine and Chinese Culture. Zhejiang University, Hangzhou, Zhejiang Province, China (April 19-21, 2019) 325) Lao, L. Invited Speaker. 針刺的轉換醫學: “無痛針刺”的臨床應用, 作用機理及循證醫學. Henan University of TCM, Zhengzhou, Henan Province, China (April 27, 2019) 326) Lao, L. Keynote Speaker. Graduation Ceremony, Virginian University of Integrative Medicine, Fairfax, VA, USA (June 9, 2019) 327) Lao, L. Presenter. The effect of acupuncture for treating primary insomnia. Annual symposium of the Society for Acupuncture Research (SAR), Burlington, Vermont, USA (June 27, 2019) 328) Lao, L. Presenter. Perception of the Use of Threatened and Endangered Species in Traditional Chinese Medicine among Hong Kong Public and HKU Students: Two Surveys. 18th Annual symposium of the Consortium for Globalization of Chinese Medicine (CGCM), Shangh ai, China (Aug. 9, 2019) 329) Lao, L. Keynote Speaker. The impact of evidence-medicine on acupuncture development. The 13th Conference on Methodology of Evidence-Based Medicine of Integrative Medicine. The First Affiliated Hospital of Anhui University of Chinese Medicine, Anhui, China (Aug. 17, 2019). 330) Lao, L. Invited Speaker. Research Methodology in Acupuncture Trials. Shanghai Municipal Hospital of Chinese Medicine. Shanghai, China (Sept. 20, 2019). 331) Lao, L. Invited Speaker. Research methodology of acupuncture/Chinese medicine clinical study. Division of Integrative Medicine, I.M. Sechenov First Moscow State Medical University (Sechenov University) in Moscow, Russia. (Sept. 24, 2019).

2020 332) Lao, L. Invited Speaker. Chinese Medicine and Chinese Culture. Zhejiang University, Hangzhou, Zhejiang Province, China (Zoom Meeting. Oct. 17, 31 and Nov. 7, 2020) 333) Lao, L. Panel Moderators. Panel: Integration of Traditional Chinese Medicine (TCM) With Weste rn Me dicine for Cancer Treatment, Prevention and Research. Trans NCI-NIH Conference on

International Perspectives on Integrative Medicine for Cancer Prevention and Cancer Patient Management, NCI, NIH, Bethesda, MD, USA (Zoom Meeting, October 28, 2020). 334) Lao, L. Presenter. TCM/Acupuncture Students Training in Oncology -- Sharing Experience from t he Univ ersity of Hong Kong. Oncology Acupuncture: From Neuroscience to Patient Wellbeing, Memorial Sloan Kettering Cancer Center, Division of Integrative Medicine. NY, USA (Zoom Meeting, Nov. 6, 2020). 335) Lao, L. Invited Speaker. Evidenced-Based Acupuncture on Pain Management. Sao Paulo Medical Acupuncture Society (CMAeSP), Sao Paulo, Brazil. (Zoom Meeting. Oct. 20, 2020) 336) Lao, L. Invited Speaker. Clinical Research Update on Acupuncture. International Symposium of Acupuncture on Pain Management (针刺镇痛国际研讨会), Nanjing University of Chinese Medicine, Nanjing, Jiangsu Province, China (Zoom Meeting. Nov. 21, 2020) 337) Lao, L. Invited Speaker. An update on Acupuncture Evidence and Clinical Research. IX Interdisciplinary Congress of Pain – CINDOR, Brazil. (Zoom Meeting. Dec. 12, 2020)