Name: Per: Date:

Microbiology: Learning through FILM & Research

Watch the trailer of the film Contagion.

1. What do you think this film is about?

2. Make a prediction to what you think will happen in the movie based on the trailer. Were there any clues given away?

What concepts do you think you need to know in Which of these concepts do you feel you already order to fully understand the film? have a good foundation? Biology: Microbiology Unit Circle items below that are KNOWN concepts

1. Bacteria

a. Cell Type (prokaryotic)

b. Classification (shape and arrangement)

c. Structure (adaptations for survival)

i. Pili, Cell wall, Flagella, Endospore

d. Reproduction

i. Binary fission, conjugation

2. Virus

a. Classification

i. Host

ii. Viral shape

iii. Genetic Material (DNA or RNA)

b. Structure (adaptations for survival)

i. Capsid, Protein spikes, envelope

c. Reproduction

i. Lysogenic cycle, Lytic cycle

3. Transmission of Infectious Disease

a. Direct Contact

b. Indirect Contact

c. Incubation Period

d. Mortality Rate

4. Treatment

a. Antibiotics vs. Antiviral drugs 5. Prevention

a. Vaccines, Quarantine

b. Epidemic

c. pandemic

Choose at least 5 of the terms and describe the film segment viewed in class.

Name: Per: Date:

Notes based on Film and Discussion Merriam Webster Dictionary

Observations: Connection to Curricular Concepts/Evidence

DAY 2 (scene 1) Transmission (Text dependent reading) Watch for symptoms Beth Emhoff portrays in the first scenes. Direct contact

Indirect Contact

DAY 3 (scene 2) CDC

DAY 4 (scene 3) Incubation Period Disease severity

Mortality Rate

Acquired Immunity (passive or active) vs. natural immunity

DAY 5 (scene 4) Epidemic Spread of disease

Pandemic

Attempts to slow spread Isolation

Quarantine

R-0 (R-nought): Doubling? Squared?

Fomites

DAY 7 (scene 9) Link to text reading

Time virus can survive on surfaces. Viruses

Bacteria

Paramyxovirus or Nipah Virus Image CDC confirm type of microbe Classification Host: DNA/RNA: Shape:

Characteristics about virus Capsid: Protein Spikes:

Bio Safety Levels BSL-4 (Biosafety level-4) [go to tab 4 and 10, 11]

DAY 8 (scene 12) Ground Zero Blogger (Alan Krumwiede)

Vaccine Vaccine Production

Antigen

Antibody

DAY 12 (scene 13) Index patient vs. ground zero Disease Spread

DAY 14 (scene 17) Infection path Contact Tracing

Ethical breach Case report vs. Controlled Case Study

DAY 18 (scene 22) Why does Thomas Emhoff not need to wear a mask? Public reactions

Government reactions

Blogger Fact vs. Fiction

DAY 21 (scene 25) Viral Genetics

Scientific updates

Dead virus Types of vaccines Live attenuated virus

R-nought/spread How does the change in r-nought affect the population?

DAY 26 (scene 26) FEMA: Governmental response

DAY 29 (scene 27) How did they know vaccine #57 was different? Vaccine production

How is the story about Nobel prize winner Dr. Barry Marshall related to the film?

DAY 131 (scene 29) Vaccine distribution How is the vaccine given to the public?

DAY 133 (scene 30) Vaccine distribution Fair or not? Who should get it first? DAY 135 (scene 33) What is the meaning behind the cold-storage scene? Vaccine storage

DAY 1 (scene 34) Conduct contact tracing: Index patient

Analysis Questions:

1. How might this outbreak have been different if the microbe was bacterial instead of viral?

2. Why was the blogger Alan Krumwiede (played by Jude Law) considered such a threat? At best he believed he was helping the public, at worst, he was just trying to make money by exploiting the situation. Regardless, his actions were making things worse. Explain how.

3. Dr. Leonora Orantes (Marion Cotillard), a World Health Organization epidemiologist, was kidnapped. Why? Did the kidnappers get what they wanted? Explain.

4. What are some examples of selfish and selfless behavior? 5. If you could choose a character you would be most like, which one would it be and why?

6. What are some examples of scientific facts and fiction in the film. Why would some areas be fictionalized.

Name: Per: Date:

Read the article regarding the Contagion Movie. Fill-in the chart depending on whether the portrayal was fact, fiction or a little of both. http://www.nytimes.com/2011/09/13/science/13view.html Name: Per: Date:

Microbiology Unit System Summative Assessment 80 points total http://healthmap.org/en/

Research an outbreak using the link below. Select an area of the world where your family or friend originates and investigate an infectious disease currently affecting the population.

Disease Name Fact Sketch theFiction bacteria, virus or fungi Virus associated with the outbreak. 3 pts 2 pts

Ground Zero Location

2 pts

CauseMortality (bacterial, Rate viral or fungal)

3 pts

Classification of Bacteria, virus or fungi Viral Infectivity 5 pts

Structural Adaptations of Bacteria, virus or fungi

5 pts Health Agency Response

Symptoms

10 pts Vaccine Production

ImmunePandemic Response (incubation rate, mortality rate etc.)

10 pts

Transmission (direct or indirect contact)

5 pts

Treatment (medications, alleviation of symptoms)

10 pts

Prevention Methods (including vaccine development)

10 pts

Possible Governmental responses

5 pts

References (keep track of sources used while researching)

5 pts

Use the culturegram http://online.culturegrams.com/world/index.php website and investigate how the population in the area might respond to an outbreak. Consider levels of infrastructure, transportation, country customs and superstitions about healthcare in your answer. [If used on NHS computers don’t need password. If use outside of NHS username is Naugatuck password is cgrams] 5 pts