Template Job Description s4

Last updated: 16th December 2015

JOB DESCRIPTION

Post title: Research Fellow – Organic Synthesis in Flow Electrochemical Reactors Academic Unit/Service: Chemistry Faculty: FNES Career pathway: ERE Level: 4 *ERE category: Research pathway Posts responsible to: Professor Richard C D Brown Posts responsible for: Post base: Non Office-based

Job purpose • To investigate and optimise oxidative electrochemical transformations in flow, targeting reactions that are of general utility in the synthesis of pharmaceutical intermediates • To investigate the scale up of selected transformations in flow electrolysis cells developed in Southampton, to enable synthesis of multigram quantities of pharmaceutical intermediates • To work with synthetic organic chemists, electrochemists and the industrial collaborator, providing regular reports on progress at meetings and through reports • To work with the collaborator and assist with the transfer of flow electrochemical synthesis technology to industrial laboratories • To contribute towards the preparation of material for publications and conference presentations

Key accountabilities/primary responsibilities % Time 1. Perform and optimise flow electrosynthesis experiments as outlined in the research proposal, 60 % including purification and full characterisation of products to a standard appropriate for publication. 2. Investigate scale up of selected reactions in flow electrochemical reactors. 15 % 3. Communication of results to project principle investigator. Attend regular project team meetings 15 % with the industrial collaborator to present results, participate in discussion and evaluation of results and project planning with other team members. Prepare reports on research progress, present results at conferences, and contribute to authorship of work to be submitted to international journals. 4. Assist in supervision and education of postgraduate and undergraduate students as appropriate 5 % and requested 5. Contribute to regular review of electrosynthesis literature and identification of industrially relevant 5 % processes for potential study.

Internal and external relationships Work as part of chemistry team on the project in Southampton reporting directly to the investigators on the project. The principle investigator (Professor Brown) will supervise individual components as appropriate, with contributions from the co-investigator (Professor Pletcher), and industry collaborator. The project requires good working relationships with the external collaborator, and will require regular reports and meetings (video / teleconference) with the external collaborator.

PERSON SPECIFICATION

How to be Criteria Essential Desirable assessed Qualifications, • Strong, first degree in chemistry (e.g. Previous experience or knowledge of Application form,

0a8fec41cfdc4873de0b5cb88969b56b.docx 1 knowledge and BSc or Masters level) the following areas could be cv, interview and experience • PhD in synthetic organic chemistry, or advantageous: letters of PhD to be awarded in the near future • Performing synthetic reactions in recommendation • Excellent knowledge of modern flow synthetic methods • Electrosynthesis • Excellent working knowledge of • Use of analytical instrumentation modern spectroscopy and analytical such as HPLC techniques • Working with industrial collaborators • Understanding of safe laboratory • Knowledge of COSHH assessment working Planning and • Practised in planning of and organising organising experimental work to achieve project objectives, and to prioritise work for completion within the given timescale • Plan work as part of a team, including logistics of some collaborative experimental work Problem • Ability to apply chemical knowledge • Ability to apply technological solving and and understanding to optimisation of solutions to reaction monitoring, initiative synthetic methodology optimisation and purification • Ability to devise, modify and optimise synthetic routes to target molecules Management • Excellent team working skills • Role model for PGs and UGs in lab and teamwork • Ability to manage project elements • Proactive in safety & lab such as budget and coordination of organisation regular meetings Communicating • Excellent verbal and written and influencing communication skills and the ability to write clearly and succinctly for publication and reports for collaborator Other skills and • Independent working and decision behaviours making when appropriate Special • Be able to work on a collaborative requirements program with a desire to understand challenges and requirements of synthesis in an industrial environment • Ability to work in industrial partners lab for short periods if required

0a8fec41cfdc4873de0b5cb88969b56b.docx 2 JOB HAZARD ANALYSIS

Is this an office-based post?

☐ Yes If this post is an office-based job with routine office hazards (eg: use of VDU), no further information needs to be supplied. Do not complete the section below.

☐ No If this post is not office-based or has some hazards other than routine office (eg: more than use of VDU) please complete the analysis below. Hiring managers are asked to complete this section as accurately as possible to ensure the safety of the post-holder.

## - HR will send a full PEHQ to all applicants for this position. Please note, if full health clearance is required for a role, this will apply to all individuals, including existing members of staff.

Occasionally Frequently Constantly ENVIRONMENTAL EXPOSURES (<30% of time) (30-60% of time) (> 60% of time) Outside work N/A Extremes of temperature (eg: fridge/ furnace) X ## Potential for exposure to body fluids N/A ## Noise (greater than 80 dba - 8 hrs twa) N/A ## Exposure to hazardous substances (eg: solvents, liquids, dust, fumes, X biohazards). Specify below: Frequent hand washing X Ionising radiation N/A EQUIPMENT/TOOLS/MACHINES USED ## Food handling N/A ## Driving university vehicles(eg: car/van/LGV/PCV) N/A ## Use of latex gloves (prohibited unless specific clinical necessity) N/A ## Vibrating tools (eg: strimmers, hammer drill, lawnmowers) N/A PHYSICAL ABILITIES Load manual handling X Repetitive crouching/kneeling/stooping N/A Repetitive pulling/pushing N/A Repetitive lifting N/A Standing for prolonged periods X Repetitive climbing (ie: steps, stools, ladders, stairs) N/A Fine motor grips (eg: pipetting) X Gross motor grips N/A Repetitive reaching below shoulder height N/A Repetitive reaching at shoulder height N/A Repetitive reaching above shoulder height N/A PSYCHOSOCIAL ISSUES Face to face contact with public X Lone working N/A ## Shift work/night work/on call duties N/A

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