LSU Health Sciences Center s2

LSU Health Sciences Center Center for Cardiovascular Diseases and Sciences

Malcolm Feist Cardiovascular Research Fellowships

SPRING 2018 – DUE MARCH 23, 2017

Applications for this award are only accepted in the Spring and Fall, for award dates of January 1 & July 1.

http://www.lsuhscshreveport.edu/Research/officeofresearch/intramuralgrants/index LSU Health Sciences Center Center for Cardiovascular Diseases and Sciences

Request For Applications

Malcolm Feist Cardiovascular Research Fellowships

Background: A major goal of The Center for Cardiovascular Diseases and Sciences (CCDS) is to promote cardiovascular research, education, and patient care.

Dedicated research time and support are vital for the development of young cardiovascular researchers and for the growth of the CCDS. Early development and support of basic scientists and clinicians will allow for the recruitment of young, promising cardiovascular researchers into the Center as junior faculty.

General Program Information: The Malcolm Feist Cardiovascular Fellowship program will fund a maximum of 6-8 fellows per fiscal year. Preference is given to applicants with the potential to be eligible for a K99, AHA Scientist Development Grant, or similar extramural funding opportunity. Applicants cannot submit the same application for consideration to two or more different intramural funding mechanisms at the same time. If an original application is not funded, applicants may submit up to two revisions of that application. No further revised versions of that application will be reviewed for support by any of the funding mechanisms. A new application with a new title and meaningful changes in substance must be prepared. Revised applications must include a clearly marked introduction indicating the changes that have been made in response to the reviewers' critiques. Applications that do not include such an introduction will be returned to the applicant without consideration. Research projects involving animals or human subjects must be approved by the IACUC or IRB respectively prior to submission of the grant application. A copy of the approved IACUC or IRB protocol (and informed consent form) should accompany the application.

Qualifications: Both basic science post-doctoral fellows and resident/clinical fellows will be allowed to submit a fellowship proposal to the CCDS. Applicants with more than 5 years of postdoctoral research experience at any institution are NOT ELIGIBLE to submit an application for a Malcolm Feist Research Fellowship. International scientists are welcome to submit fellowship applications. However, preference will be given to applicants with demonstrated proficiency in English (verbal and written). International applicants may be required to present an acceptable score on the TOEFL (Test of English as a Foreign Language, minimum score = 85) or the IELTS (International English Language Testing Service, minimum acceptable score = 6.5) test.

Funding Period: The proposed research and training plan may cover a period of 1, 2 or 3 years. Preference will be given to applicants seeking more than one year of research training. The initial application should specify the total length of the project, with corresponding budgets for each project year, as well as a cumulative budget. The duration of funding should reflect the amount of work proposed. For example, applicants proposing three-year projects should prepare a research plan reflecting three years of work. Fellowships are funded in 1-year increments. The Board can renew a CCDS Fellowship twice, for a total funding period of 3 years. Continued funding by the Board in years 02 and 03 is contingent upon the fellow’s productivity and progress on the project.

2  Budget: The total budget for the Fellowship will not exceed $60,000 per year. The amount budgeted for the fellow’s salary cannot exceed the amount dictated by institutional policy. The remaining funds can be dedicated for research supplies, travel, etc. Technical support and equipment purchases are not allowed. The initial application should include a budget for each project year of proposed support as well as a cumulative budget. Fellowship support can be secured for up to 3 years, contingent upon research progress and productivity. The cumulative budget cannot exceed $180,000 ($60,000 per year). Funds will be dispersed for project start dates of January 1 or July 1. Unused funds must be returned to the Center at the end of the project.

Reporting: A final report is due to the Board no later than 1 month after the end of the project.

A completed and signed Intramural Routing Sheet (Lite Green Sheet) for Intramural Applications must be submitted with the application. The Intramural Routing Sheet form is located on Office of Sponsored Programs website: http://lsuhscshreveport.edu/Research/officeofresearch/intramuralgrants/index

Submission Instructions: Applications will be accepted twice a year (approximately March and October) for funding to begin on July 1st or January 1st. Scan and include the completed and signed Intramural Routing Sheet (Lite Green Sheet) with the intramural application. The completed intramural application package will be emailed in PDF format to the Office for Sponsored Programs ([email protected]) and the CCDS ([email protected]) by 5PM on March 23, 2018.

NOTE: OSPTT is no longer requiring the original signature documents (Intramural Routing Sheet and application signature page) be delivered prior to grant submission. These signed documents must be included in the scanned application package. Applications submitted without these documents and/or signatures will be rejected for submission.

The PDF intramural application package will be named as follows: Malcolm Feist CV Res Fellowship_Last Name_First Name

Mentor/Sponsor Requirements: A cardiovascular researcher at LSUHSC must mentor Recipients of these Fellowships. A letter from the faculty mentor/sponsor indicating his/her willingness to serve in this capacity is required. The letter must include a summary of the training plan for the fellow and alternate funding sources that may be applied to the project. Only one post-doctoral fellow and one pre-doctoral fellow per faculty mentor will be funded. Preference is given to applicants with the potential to be eligible for a K99, AHA Scientist Development Grant, or similar extramural funding opportunity. The mentor should describe the applicant’s eligibility for extramural funding in the letter of support accompanying the application. If a project involves multiple PI’s, one PI must be designated as primary. If the sponsor does not have active extramural funding, then evidence must be provided (in the initial application and subsequent progress reports) that he/she has submitted at least one research proposal for national funding during the previous year. The mentor must submit an annual evaluation of the recipients’ progress for review by the CCDS Board of Directors. Individuals listed as collaborators must also submit a letter indicating his/her willingness to serve in this capacity and provide a brief description of what he/she will contribute to the project.

3 Evaluation: Applications will be reviewed by the CCDS Board of Directors (possibly with the assistance of relevant experts not serving on the Board). Priority for funding will be based on the qualifications of the applicant and sponsor, the training potential of the research plan, and commitment of the applicant, sponsor, and Department to the training experience. Applicants are encouraged to review the Malcolm Feist Cardiovascular Research Fellowship Peer Review Form prior to submitting their application. All applicants will receive a copy of their final Peer Review Forms.

FONT SIZE: Arial 11. Provide at least one-half inch margins (top, bottom, left and right) for all pages. No applicant-supplied information can appear in the margins.

LSU Health Sciences Center Center for Cardiovascular Diseases and Sciences

Malcolm Feist Cardiovascular Research Fellowship

Principal Investigator (Fellow)______Last Name First Name Middle

Position: ______Phone # ______

Department: ______

Project Title: ______

Funding Sources: CENTER FOR CARDIOVASCULAR DISEASES AND SCIENCES

Deadline: SPRING 2018 - DUE MARCH 23, 2018. Applications only accepted twice a year (Spring and Fall).

Duration of Project: ______1 Year ______2 Years ______3 Years

Period of Award (3 year maximum) _____/_____/______to ______/______/______MM DD YYYY MM DD YYYY

Total Amount Requested: $ ______($180,000 maximum)

Percent of Applicant’s Total Effort Devoted to this Project: ______%

______Fellow Signature Faculty Mentor/Sponsor

______Department Head Signature

5 TABLE OF CONTENTS (Example)

1. FACE PAGE ...... 1

2. TABLE OF CONTENTS...... 2

3. PROJECT SUMMARY ...... 3

4. BUDGET PAGES …...... 4- 7

5. BIOGRAPHICAL SKETCH (Fellow) ...... …8

6. BIOGRAPHICAL SKETCH (Faculty Mentor/Sponsor) ...... …9

7. RESEARCH SUPPORT...... 10

7. RESEARCH PLAN...... 11-20

8. LITERATURE CITED - 2 page Limit ...... 21-22

9. APPLICANT STATEMENT…………………………………………………………………………23

Each application MUST include items 1-9 in order to be considered.

APPENDIX: LIMIT TO THOSE ITEMS ABSOLUTELY NECESSARY FOR GRANT REVIEW

6 Fellow ______

ABSTRACT OF RESEARCH PLAN

Description: State the application’s broad, long-term objectives and specific aims. Describe concisely the research design and methods for achieving these goals. Avoid summaries of past accomplishments and use of the first person. This abstract is meant to serve as a succinct and accurate description of the research plan for use by the review committee. DO NOT EXCEED 200 WORDS. ______

______PERSONNEL ENGAGED ON PROJECT, including Fellow, Mentor* and Collaborators* ______Name ______Name ______Position Title ______Position Title ______Department ______Department______

Name ______Name ______Position Title ______Position Title ______Department ______Department______

* Letters required as described above (page 2)

7 Fellow ______

BUDGET DETAIL (YR 01)

Budget should include sufficient funds for the proposed project, but should not exceed maximum level recommended for relevant award.

1. Salary * Support for Fellow:

2. Supplies and Operating Expenses (Please Itemize):

3. Travel

4. Other Expenses (Please Specify):

TOTAL BUDGET $ ______(Not to exceed $60,000)

*Salary support cannot exceed annual stipend levels (for time-in rank) dictated by institutional policy.

8 Fellow ______

3. Travel

9 Fellow ______

3. Travel

10 Fellow ______

CUMULATIVE BUDGET

Year 1* Year 2* Year 3* Cumulative**

Salary Support for Fellow

Supplies and Operating Expense

Travel

Other Expenses

Total Budget *total budget may not exceed $60,000 per year **cumulative total may not exceed $180,000

11 Fellow ______

BIOGRAPHICAL SKETCH (Fellow)

Give the following information for the Principal Investigator.

NAME ______POSITION/TITLE: ______

MEMBERSHIPS AND HONORS:

EDUCATION (Begin with baccalaureate or other initial professional education and include postdoctoral training). YEAR FIELD INSTITUTION & LOCATION DEGREE OF STUDY CONFERRED ______

______RESEARCH AND PROFESSIONAL EXPERIENCE: Concluding with present position, list in chronological order, previous employment, experience, and honors. List, in chronological order, the titles, all authors, and complete references to all scientific articles (except abstracts) published by the applicant. DO NOT EXCEED TWO PAGES. If the list exceeds 2 pages, include only the most recent publications.

12 Fellow ______

BIOGRAPHICAL SKETCH (Faculty Mentor/Sponsor)

A 3-page NIH biosketch (including support information) may be substituted.

Give the following information for the Principal Investigator.

NAME ______POSITION/TITLE: ______

MEMBERSHIPS AND HONORS:

EDUCATION (Begin with baccalaureate or other initial professional education and include postdoctoral training). YEAR FIELD INSTITUTION & LOCATION DEGREE OF STUDY CONFERRED ______

______RESEARCH AND PROFESSIONAL EXPERIENCE: Concluding with present position, list in chronological order, previous employment, experience, and honors. Include present membership on any Federal Government public advisory committee. List, in chronological order, the titles, all authors, and complete references to all publications (except abstracts) during the past three years and to represent earlier publications pertinent to this application. DO NOT EXCEED TWO PAGES.

13 Fellow ______

Research Support (Faculty Mentor/Sponsor) (Use Continuation Pages if Necessary)

List, in four separate groups:

(1) Active support; (2) applications and proposals pending review or funding; (3) applications and proposals planned or being prepared for submission; and (4) projects funded in the past. Include all Federal, non-Federal, and institutional grants and contract support. If none, state "none". For each item give the source of support, identifying number, project title, name of principal investigator, time or percent of effort on the project, annual direct costs, and entire period of support.

(1) ACTIVE SUPPORT:

(2) PENDING APPLICATIONS:

(3) APPLICATIONS PLANNED OR BEING PREPARED:

(4) PROJECTS FUNDED IN THE PAST 5 YEARS:

14 Fellow ______

Research Plan

The suggested format for the Research Plan (Arial 11 Font) is:

(A) Specific Aims. State concisely and realistically what the research described in this application is intended to accomplish and/or what hypothesis is to be tested.

(B) Significance. Briefly sketch the background to the present proposal, critically evaluate existing knowledge, and specifically identify the gaps which the project is intended to fill. State concisely the importance of the research described in this application by relating the specific aims to longer term objectives.

(C) Experimental Design and Methods. Discuss the experimental design, methodology and procedures proposed to accomplish the specific aims of the project.

(D) Relevance to Cardiovascular Disease. Briefly state the relevance of proposed research to cardiovascular disease.

Items (A) through (D) may not exceed 10 single spaced pages.

(E) Literature Cited. Site only references pertaining to application. Do not exceed two pages for references. This section is not included in the10 page limit.

(F) A letter from the faculty mentor/sponsor indicating his/her willingness to serve in this capacity is required. The letter must include a summary of the training plan for the fellow and alternate funding sources that will be applied to the project, and must address all of the issues outlined under Mentor/Sponsor Requirements on page 2 (above).

(G) Applicant statement. Briefly summarize your long-term career goals and describe how receipt of this fellowship will contribute to the realization of those goals. (1/2 page maximum)

(H) Approved IACUC or IRB Protocol: Include IACUC and/or IRB protocol and documentation signifying its approval.

(I) Collaborator Letter. Submit letters of support from collaborators named in the “Personnel Engaged on Project” section of this application.

APPENDIX: Limit to those items absolutely necessary for grant review.

15 The Peer Review Form that will be used by the reviewers of your application can be found on the Office of Research website.

Fellow ______

Research Plan (10 page limitation, Arial Font 11)

Description: Use this section to describe the research plan as outlined on the previous page.