Dr. Reza Entezari Heravi, Pharm.D, Ph.D of Pharmaceutical Biotechnology
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CVCV RezaReza Entezari Entezari Heravi, Heravi, Ph.D Ph.D (Biotechnology)(Biotechnology)
Dr. Reza Entezari Heravi, Pharm.D, Ph.D of Pharmaceutical Biotechnology,
School of Pharmacy, Mashhad University of Medical Sciences (MUMS)
Date of Birth: 18.06.1981- Tehran
Marital Status: Married
Ph.D average score: 19.03
EDUCATION
2000-2006 School of Pharmacy, Mashhad University of Medical Science
2006-2014 School of Pharmacy, Biotechnology assistant (Ph.D)
2014 till now Assistant professor in Biotechnology department, Zabol University of medical Sciences
MEMBERSHIP
1. Iranian Committee of Biotechnology
2. Iranian Committee of Genetics
3. Frankfurt Innovation Center, Max-Planck Institute, Frankfurt am Main, Germany
PROFESSIONAL EXPERIENCES
1. Epidemiological studies
2. Genetic polymorphism
3. HPLC methods
4. Drug design & Drug discovery
5. Molecular Modeling 6. Molecular Docking
7. Bioinformatics
8. Gene expression profiling
9. Transcriptome studies (cDNA Microarrays, Real-time PCR)
10. Natural anti-sense technology
11. Transgenic animals and plants
12. Cancer biomarkers
13. Teaching Molecular and Cellular Biology and Biotechnology in Azad University of Pharmacy, Tehran
14. Real-time PCR
15. Primer Design
16. Stem Cells and their differentiation
CERTIFICATES/COURSES
1. SPSS workshop, 2009
2. Transcriptome for cDNA microarray workshop, 2007
3. Six-month scholarship in Max-Planck Institute, Frankfurt Innovation Center, GenXPro, Frankfurt am Main, Germany, June 2010-January 2011 (working on Next-generation sequencing)
4. Supre-SAGE courses for cancer biomarkers, Frankfurt am Main, Germany, 2011
5. Complexity systems and Chaos theory, Santa Fe Institute, New Mexico, USA, 2014
COMPUTER SKILLS
Microsoft Office (Word, Excel, Outlook, Power Point), Photoshop, Adobe Acrobat, Endnote, ChemOffice, GenePix Microarray Software, Misc. PCR designer software, SPSS statistical analysis and among many others, NCBI methods.
RESEARCH INTERESTS
1. Epigenetic profiling of complex diseases (i.e. late-onset Alzheimer’s, cancer, PTSD) 2. Pharmacoepigenomics (drug-epigenome interactions)
3. Influence of environment (e.g. nutrition, radiation) on human health and epigenetic integrity
4. Development of epigenetic profiling methods (microarrays and nucleotide chemistry)
5. Bioinformatics
6. Cancer signaling pathways
7. Drug design for cancer therapy
8. Stem Cell differentiation
AWARDS
1. Second rank in 10th seminar of Iranian Pharmacist, Mashhad, 2003
2. First rank in all student of biotechnology, Mashhad pharmacy school, 2007
3. The Best Researcher of Mashhad University of Medical Sciences, 2009
4. The Best book translator of Mashhad University of Medical Sciences for the Book: “ Molecular Biotechnology, Bernard Glick and Jack J Pasternack”, 2009
5. Membership of Frankfurt Innovation center, GenXPro, Frankfurt am Main, Germany, 2010
6. Certificate form for working with Prof. Dr. Guenter Kahl, Johann wolfgang Goethe University for research about Natural anti-sense biomarkers in Pancreatic cancer using Super-SAGE methods
7. 93rd Canadian Chemistry Conference and Exhibition. May 29 –June 2, 2010. Toronto. Canada. Reza Entezari Heravi, Farzin Hadizadeh, Jalil Tavakol Afshari, Mojtaba Sankian and Javad Behravan. Synthesis and activity of new analogs of selecoxib as cyclooxygenase 2 (COX-2) inhibitors.
PUBLICATIONS AND ARTICLES
1. The Biotechnology reference book: Molecular Biotechnology, Bernard Glick and Jack J Pasternack, 2009 2. Book: Bioinformatic for Dummies
3. Book: Encyclopedia of Foods (In Press)
4. Association of CYP2A6*1 and CYP2A6*4 with nicotine metabolism in an Iranian population (DNA and Cell Biology)
5. Association of MDR1 gene polymorphism with gastric cancer in an ethnic Iranian population (Indian Journal of Cancer)
6. Association of MDR1 gene polymorphism with colorectal cancer in an Iranian population (Molecular Biology Reports)
7. Association of MDR1 gene polymorphism and ALL in Iranian population (Iranian Journal of Blood and Cancer)
8. Novel selective Cox-2 inhibitors induce apoptosis in Caco-2 colorectal carcinoma cell line (European Journal of Pharmaceutical Sciences)
9. Cyclooxygenase-2 inhibitors increases Bax/Bcl-2 ratio and up-regulates Caspase-3 gene expression (Genes & Genomics)
LANGUAGE
Fluent in English, Average in German
OTHER RESEARCH
1. Modeling, Design and biological evaluation of four celecoxib analogous as apoptosis inducer in colorectal cancer cell lines
2. Evaluation of four celecoxib analogous as MAP kinase inhibitors
MY THESIS
Gene expression profiling of Caco-2 colorectal cancerous cell line in response to four new analogous of celecoxib by using cDNA microarray method. Projects in Process
1. Differentiation of human adipose and bone marrow stem cells to beta-islet pancreatic cells to produce insulin.
2. Design, Modeling and Synthesis of new Histone deacetylase inhibitors as new drugs for pain relief.
Contact me:
E-mail:[email protected]