Curriculum Vita s6

Curriculum Vita

Douglas P. Boyd, PhD

As of July 8, 2002

PRESENT POSITIONS:

Chief Scientist, GE-Imatron 389 Oyster Point Blvd, So. San Francisco, CA 94080 Tele: 415-583-9964 Imatron is a public company that develops and manufactures Ultrafast CT scanners for use in hospitals and clinics. (NYSE: GE)

Adjunct Professor of Radiology, Univsersity of Califronia, San Francisco UCSF is the leading academic radiology department

Board of Directors, Invision Technology, Inc., Newark CA. InVision is a public company that develops and manufactures airport baggage scanners for explosive detection, landmine detectors, and wood vision products. (Nasdaq: INVN)

Board of Directors, Imaging Technology Group, Inc., South San Francisco, CA. ITG is a private corporation that owns and operates Heartscan imaging centers that employ EBT scanners for screening applications.

Board of Directors, Thermatrx, Chicago. Thermatrx is a private corporation that has developed a revolutionary advanced prostate treatment device based on microwave technology.

PREVIOUS PROFESSIONAL POSITIONS:

1968-1970: Member Technical Staff, Bell Telephone Laboratories, Murray Hill, N.J.

1970-1976: Research Physicist. Stanford University, W.W. Hansen Laboratories of Physics

1976-1984: Professor of Radiology, University of California, San Francisco

1984-- Adjunct Professor of Radiology, University of California, San Francisco—an honorary clinical appointment that is renewed from time to time in exchange for teaching services. Boyd CV Page 2 1983-1990: President, CEO, and Founder of Imatron, Inc.

1990-2001: Chairman of the Board, and CTO, Imatron Inc.

1995-2002: Chairman of the Board and founder, Accuimage Diagnostics Inc. (Nasdaq:AIDP.OB)

EDUCATION:

B.S. Physics, 1963, The University of Rochester, Rochester, N.Y. PhD, Physics, 1968, Rutgers University, New Brunswick, N.J.

PROFESSIONAL AFFILIATIONS:

Founding Board Member: The IEEE Society for Medical Imaging Past Member: The American Association of Physicists in Medicine Past Member: The American Physical Society Editorial Board: The American Journal of Cardiac Imaging Member: The North American Society of Cardiovascular Radiology

HONORS AND AWARDS:

1990 Testified before the Presidential Commission on Airline Safety, Washington DC 1991 Invited Speaker, Japan Assoc. for Medical Imaging Technology 1991 Keynote Address, The American Society for Nondestructive Testing, San Diego 1992 Invited Speaker, The 11th Congress of the Japanese Society of Medical Imaging 1993 Conway Safe Skies Award, World Development Council, Singapore. Competitive annual award recognizing the most significant contribution to international air transport safety. 1993 Stanford University Alumni magazine feature recognizing the third largest contribution to Stanford’s patent licensing fund. 1994 Professor Sabino Di Rienzo International Award, nomination. The Di Rienzo Foundation, Buenos Aires, Argentina. Competitive award based on contributions to advances in Radiology. 1996 Nominated: Engineer of the Year, Design News Magazine. 1998: Elected as Fellow of the American Institute for Medical and Biological Engineering. 2002 Named Scientist of the Week, www.vp.org

RESEARCH CONTRIBUTIONS:

Dr. Boyd has contributed to the fields of imaging technology, accelerator and beam physics, superconducting systems, nuclear physics, and medical physics. He developed the first fan beam-Xenon detector CT system, which was licensed to GE. The development of electron beam-based Ultrafast CT, manufactured by Imatron, Inc., has led to a number of advances in diagnosis and treatment, particularly in the fields of Boyd CV Page 3 cardiology and wellness. The development of the CTX-5000 explosives detection scanner, manufactured by InVision, promises to have a major impact on airline security in the future. He holds several patents and has published more than 100 articles in these fields.

PATENTS (partial list):

US 3,983,398 Method and apparatus for x-ray and gamma-ray 3-D tomography using a fan beam.

US 4,075,491 Position sensitive x-ray or gamma-ray detector and 3-D using same.

US 4,079,492: Fan beam x- or gamma-ray 3-D tomography.

US 4,138,721 Non-rotary fan beam x- or gamma-ray 3-D tomography.

US 4,352,021 X-ray transmission scanning system and method and electron beam x-ray scan tube for use therewith.

US 4,736,396 Tomosynthesis using High-Speed CT Scanning System

US 4,993,055 Rotating X-ray Tube with External Bearings.

US 4,977,585 Self Shielded Computerized Tomographic Scanner

US 5,014,293 Computerized Tomographic X-ray Scanner System and Gantry Assembly

US 5,105,456 High Duty-Cycle X-ray Tube

US 5,721,889 Scanned volume CT scanner

US 5,491,734 Off-axis scanning electron beam computed tomography system

US0144492 Electronic beam Computed Tomographic scanner system with helical or tilted target, collimator and detector componets to eliminate cone beam

PUBLICATIONS (partial list):

Boyd D, Kane JV: Alternating gradient accelerating tube. Rev. Sci. Instr. 37:555, 1967.

Boyd D, Donovan PF, Mollenaur JF: Analysis of the reaction D+P->P+P+N. Phys. Rev. 39:595, 1967.

Dovovan PF, Kane JV, Mollenauer JF, Zupancic C, Boyd D: He3+p elastic scattering from 12.6 to 15.4 meV. Phys. Rev. 158:973, 1967. Boyd CV Page 4

Boyd D, Dovovan PF, Mollenauer JF: The proton-neutron final-state interaction. Phys. Rev. 188:1544, 1969.

Assimalopoulos P, Beardsworth E, Boyd D, Donovan PF: Coincidence studies of the reaction d+He3 and d+He4. Nucl. Phys. A144:272, 1970.

Nagatani K, Boyd D, Donovan PF, Beardsworth E, Assimalopoulos P: Doule spin- isospin-flip reaction. Phys. Rev. Letts. 24:675, 1970.

Boyd D, Fairbank WM, Schwettman HA, Simpson J: A cryogenic source of negative pions for cancer therapy. Proc. of the Helium Society Symposium, Washington DC< May 1971.

Boyd D, Rand R, Rothbart G, Barth E: Coaxial and printed circuit delay lines for multi- wire proportional chamber readout. IEEE Trans. Nucl. Sci. NS-19:148, 1972.

Bagshaw MA, Boyd D, Fairbank WM, Kaplan HS, Ki GC, Schwettman HA, Palos BB: Clinical dosimetry for negative pi-mesons. Radiology 108:197, 1973.

Boyd D, Schwettman HA, Simpson J: A large acceptance pion channel for cancer therapy. Nucl. Instr. and Meth. 111:315, 1973.

Kaplan HS, Bagshaw MA, Schwettman HA, Fairbank WM, Boyd D: A hospital-based superconducting accelerator facility for negative pi-meson beam radiotherapy. Radiology 108:159, 1973.

Boyd D, Coonrod J, Dehnert J, Chu D, Lim C, MacDonald B, Perez-Mendez V: A high pressure Xenon proposrtional chamber for x-ray laminogrpahic reconstruction using fan beam geometry. IEEE Trans. Nucl. Sci. NS-21:184, 1974.

Li GC, Boyd D, Schwettman HA: Pion dose calculations suitable for treatment planning. Physics in Med. and Biol. 19:436, 1974.

Boyd D: Instrumentation for fan beam computerized tomography of the body. In: Image Processing for 2-D and 3-D Reconstruction from Projections, published by the American Optical Society, page TuA6, August 1975.

Dreike P, Boyd D: Convolution reconstruction of fan beam projections. Computer Graphics and Image Processing 5:459, 1976.

Boyd DP, Korobkin MT, Moss A: Engineering Status of CT Scanning; SPIE Vol. 96 Optical Instrumentation in Medicine V, p303-312, 1976. Boyd CV Page 5 Boyd D, Korobkin M, Margulis A: Comparison of translate-rotate and pure rotary CT body scanners. In: Proc. of SPIE Applied Optical Instruments in Medicine VI. October 1977.

Boyd, DP: Computerized-Tomography: Isotope Sources; Int. J. Radiation Oncology Biol. Phys. 3:53-56, 1977.

Brasch RC, Boyd DP, Gooding CA: Computed Tomography scanning in Children: Comparison of Radioation Dose and Resolving Power of Commercial CT Scanners, Am. J. of Roentenology 131:95-101, 1978.

Boyd D, Moss A, Korobkin M: Engineering status of CT. Optical Eng. 16:27, 1977.

Genant HK, Boyd D: Quantitative bone mineral analysis using dual-energy computed tomographic scanning. Invest. Radiol. 12:545, 1977.

Lim CB, Cheng A, Boyd D: A fast iterative method for 3D positron image rexonstuction. ANS Trans: 26:154, 1977.

Norman D, Price D, Boyd D, Fishman R, Newton TH: Quantitative aspects of CT scanning relating to blood and CSF. Radiology 123:335-338, 1977.

Pistenman DA, Fessenden P, Boyd DP Luxton G, Taber R, Bagshaw M: Initial performance of the Stanford Medical Pion Generator (SMPG). Radiology 122:597, 1977.

Hanson K, Boyd D: The characteristics of CT recosntruction noise and their effect on detectability. IEEE Trans. Nucl. Sci. NS-25(1):160-163, 1978.

Lim CB, Cheng A, Boyd D, Hattner RS: A 3D iterative reconstruction method for stationary planar positron cameras. IEEE Trans. Nucl. Sci. NS-25:196, 1978.

Boyd D: Recent progress in CT hardware develoopment. In: Symposium on Physical and Technical Aspects of Transmission and Emission Computed Tomography, pages A4-11, Tokyo, January, 1978.

Abols Y, Genant HK, Rosenfeld D, Boyd D, Ettinger B, Gordon GS: Spinal bone mineral determinations using computerized tomography in patients, controls and phantoms. In: Proceedings of the 4th Interantional Conference on Bone Measurement, Toronto, 1978.

Brasch R, Gooding C, Boyd D: CT body scanning in children: comparison of radiation dose and resolving power of several commercial scanners. Am. J. Roentgen. 131:95-101, 1978.

Norman D, Diamond C, Boyd D: Relative detectability of intracranial calcifications in computed tomograpms and skull radiography. J. Computed Assisted Tomography 2:61- 64, 1978. Boyd CV Page 6

Lipton MJ, Hayashi TT, Boyd DP, Carlsson E: Ventricular Cast Volume Measurements by CT; Radiology 127:419-423, 1978.

Boyd DP, Gould RG, Quinn JR, Sparks R, Stanley JH, Hermannsfeldt WB: A Proposed Dynamic 3-D Densitometer for Early Detection and Evaluation of Heart Disease, IEEE Trans Nuclear Science, NS-26:2724, 1979.

Boyd DP: Status of Diagnostic X-Ray CT; IEEE Trans. on Nuclear Science. Vol. NS- 26(2):2836-2839, 1979.

Boyd D, Axel L, Cann C: New clinical applications of CT scanning. Toshiba Review 3:36-42, 1979.

Federle MP, Moss AA, Boyd D, Royal SA: Coronal and sagittal reconstructions using a 4.8 second CT body scanner. Am J Roent 133:625-632, 1979.

Smith V, Parker DL, Stanley JH, Phillips TL, Boyd DP, Kan PT; Development of a Computed Tomographic Scanner for Radiation Therapy Treatment Planning; Radiology 136:489-493, 1980.

Boyd, D. Theoretical possibilities for future CT technology. Diagnostic Imaging Dec. 1982.

Boyd, DP, Couch, JL, Napel, SA, Parker, DL, Peschmann, KR, Herrmansfeldt, W.: High-speed multi-slice, x-ray computed tomography. IEEE International Workshop on Physics and Engineering in Medical Imaging, 1982.

Rowan, WH, Boyd, DP, Couch, JL, Ortendahl, D: Algorithms for limited-angle computed tomography. IEEE 1982 Workshop on Physics and Engineering in Medical Imaging, 1982.

Boyd, DP, Lipton, MJ: Cardiac Computed Tomography. Proc. IEEE 71:298-307, 1983.

Gould, RG, Couch, JL, Napel, SA, Peschmann, KR, Rand, RE, Boyd, DP: Performance characteristics of an Ultrafast scanning electron beam CT scanner. Proc. AAPM 1983.

Lipton, MJ, Boyd, DP: Measurement of regional myocardial perfusion by CTT.: In CT of the Heart and Great Vessels, ed. C. Higgins. Futura Publishing Company, 1983.

Lipton, MJ, CB Higgins RJ Herfkens, BH Brundage DP Boyd. Initial Results with Cine- CT; Journal of Computer Assisted Tomography 8(2):362,1984.

Lipton MJ, Higgins CB, Farmer D, Boyd DP: Cardiac Imaging with a High-Speed Cine- CT Scanner: Preliminary Results; Radiology 152(3):579-582, 1984. Boyd CV Page 7 Peschmann, KR, Napel, S, Couch, JL, Rand RE, Alei, R, Ackelsberg, SM, Gould, R., and Boyd, DP: High-speed computed tomography: systems and performance. Applied Optics, Vol 24:4052-4060, 1985.

DW Farmer, MJ Lipton, CB Higgins, H. Ringertz, PB Dean, R. Sievers, DP Boyd; In Vivo Assessment of Left Ventricular Wall and Chamber Dynamics during Transient Myocardial Ischemia using Cine CT; American Journal of Cardiology; 55:560-656, 1985.

Lipton MJ, Higgins CB, Boyd DP: Computed Tomography of the Heart: Evaluation of Anatomy; Journal of the American College of Cardiology: 5(1):555-695, 1985.

Lipton MJ, Brundage BH, Higgins CB, and Boyd DP: Clinical Applications of Dynamic Computed Tomorgraphy; Progress in Cardiovascular Diseases, 28(5):349-366, 1986.

Boyd DP, Couch JL, Napel SA, Peschmann KR, Rand RE; Ultra Cine-CT for Cardiac Imaging: Where Have We Been? What Lies Ahead?; American Journal of Cardiac Imaging 1(2):175-185, 1987.

Boyd DP, and Haugland, CH: “Ultrafast CT” (review article), in Innervision Vol.5, No.12, Published by Hagbros Publishing Co., Ltd, Tokyo, 1990.

Boyd, DP: “The Development of Ultrafast CT and its Future Prospects” Japanese Society of Medical Imaging Technology, Med. Imag. Tech. Vol. 9, No. 3, p237-242, June 1991.

Hasegawa, BH, Stebler, B, Rutt, BK, Martinez, A., Gingold, EL, Barker, CS, Faulkner, KG, Cann, CE, Boyd, DP: Prototype high-purity germanium detector system with fast photon counting circuitry for medical imaging. Medical Physics, Sept/Oct 1991.

Boyd, DP: “Screening for Coronary Artery Disease Using Ultrafast CT” Proceedings of the Cardiovascular Science and Technology Conference, Dec. 12-14, 1992, p19, The Association for the Advancement of Medical Instrumentation (abs.).

Boyd, DP and Haugland, CH: Recent Progress in Electron Beam Tomography: Med. Imag. Tech. Vol. 11,No. 5, page 578-585, December 1993.

S. M. Song, D. P. Boyd, R. M. Leahy, Bruce H. Brundage, S. A. Napel: "Determining Cardiac Velocity Fields and Intraventricular Pressure Distribution for a Sequence of Ultrafast CT Cardiac Imaging." IEEE Transactions on Medical Imaging, March 1993.

Boyd D: Advances in Computed Tomography Innovations; Administrative Radiology Journal, July 1996.

Book Chapters Boyd CV Page 8 Boyd D: Physics priniples; computerized tomography. In: Alimentary Tract Roentgenorgraphy III (Imaging). Eds: Margulis nad Burhenne. St. Louis, CV Mosby Co., p.1-11, 1979,

Margulis AR, Boyd DP, Korobkin M: Comparison of bimodal and pure rotary CT body scanners. In: Total Body Computerized Tomography ed. by P. Gerhardt and G. Van Kaick, George Thieme Verlag, Stuttgart, 1979.

Lipton MJ, Boyd DP: Quantitation in the heart by CT imaging. Mos aa, Goldberg HI (eds): Computed Tomography, Ultrasound and X-Ray: An Integrated Approach, Univ. of California, San Francisco Ext. Programs in Med. Education press, p275-278, 1980.

Boyd, D. P. Transmission Computed Tomography. In Radiology of the Skull and Brain, Vol. 5, eds. T.H. Newton , D.G. Potts., St. Louis: C.V. Mosby Company, 1981.

Henant HK, Boyd D, Rosenfeld D, Abols Y, Cann E: Quantitative bone mineral analysis using computed tomography. In: Non-Invasive Measurements of Bone Mass and Their Clinical Application. ed. S. Cohn, CRC prss, 1981,

Lipton MJ, Boyd DP: Contrast Media in Dynamic Computed Tomogrpahy of the Heart and Great Vessels; in Contrast Media in Computed Tomography International Workship, Berlin Jan 14-17, 1981; Published by Exerpta Medica, Amsterdam-Oxford-Princeton.

Boyd DP, Lipton MJ. Future Directions for CT Technologies; in SPSE conference Proceedings Image Analysis Techniques and Applications, Tucson Az, Jan 1981.

Lipton MJ and Boyd DP: Contrast media in dynamic computed tomography of the heart and great vessels. In: Contrast Media in Computed Tomography, International workshop, Berlin, January 14-17, 1981, Published by Exerpta Medica, Amsterdam-Oxford- Princeton.

Lipton MJ, Brundage BH, Higgins CB, Boyd DP: CT Scanning of the Heart; in Cardiovascular Clinics, 1982.

Boyd, DP, Parker, DL: Basic principles of computed tomography. In Computed Tomography of the Body, eds. A. Moss, G. Gamsu. H. Genant. W.B. Saunders Co., 1983.

Lipton, MJ, Boyd, DP: Computed transmission tomography for cardiovascular diagnosis. In: Recent Advances in Radiology and Medical Imaging, Ed. R.E. Steiner. Churchhill Livingston, 1983.

Boyd, DP: Computerized transmission tomography of the heart using scanning electron beams. In CT of the Heart and Great Vessels, ed. C. Higgins. Futura Publishing Company, 1983. Boyd CV Page 9 Lipton MJ, Boyd DP: Measurement of Regional Myocardial Perfusion by CTT: in CT of the Heart and Great Vessels, ed. C. Higgins, Futura Publishing Co., 1983.

Boyd, DP, Korobkin, M., Moss, A.: Instrumentation; Computed Tomography. In Alimentary Tract Radiology, Vol. 1, eds: A. Margulis, and H.J. Burhenne. St. Louis: CV Mosby Compnay, 1983.

Lipton, MJ, Boyd, DP: Computed tomography in cardiovascular disease. In Disease in Sectional Imaging Methods: A Comparison, eds. J. Littleton and M. Durizch. University Park Press, 1983.

MJ Lipton, CB Higgins, DP Boyd; in NMR, CT, and Interventional Radiology, pp81-91, edited by Moss, Ring and Higgins, 1984.

S. G. Magistri, S. A. Napel, K. R. Peschmann, R. E. Rand, J. L. Couch, M.J. Lipton, DP. P. Boyd, "Recent Technical Advances in Cine-Computed Tomography". In New Developments in Imaging, R. Ch. Otto and C. B. Higgins, Editors, Thieme Medical Publishers, Inc., 1986.

Jaschke, W., Gronemeyer, DHW Seibel, RMM, Boyd DP: Perspektiven fur CT- gesteuerte Punktionstechniken durch Ultra-Fast-Cine-CT. In Interventionelle Computer- tomographi Lehrbuch und Atlas zur interventionellen Operationstechnik und Schmerztherapie, eds. Gronemeyer and Seibel, Ueberreuter Wissenshaft, Berlin, 1989, and Interventional Computed Tomography, Blackwell Scientifc, 1990.

Boyd, DP, Parker DL, Goodsit MM: Principles of Computed Tomography; chapter 29 in CT/MR of the Body, ed: Moss AA, Gamsu G, Genant HK, W.B. Saunders Co., 1991.

Boyd DP; Technology Requirements for Computed Tomographic Imaging; in Proceedings of the Symposium on Technology Requirements for Biomedical Imaging, Georgetown University, May 22-23, 1991

Boyd, DP, and King, D: “Screening for coronary artery disease without contrast media using Ultrafast CT” in Proceedings of the 5th International Symposium on Magnetic Resonance - MR’93, Garmisch-Partenkirchen, 1993.

TEACHING:

Mr. Dan Boome, PhD, University of California, Irvine, Thesis examination committee, Dept. of Radiological Sciences, 1988

Ms. Elzbieta Mazur, PhD The University of Manitoba, Examiner for PhD orals, Depts of Botany and Radiology, 9/15/93

PUBLIC SERVICE: Boyd CV Page 10 Editorial Advisory Board: The American Journal of Cardiac Imaging

Reviewer: NIH committees, National Academy of Science committees, several scientific journals, etc.