Normal DTI Database of Cervical Spinal Cord

Normal DTI database of Cervical spinal cord Appendix I: Table 1 Mean with standard deviation of fractional anisotropy (FA) value in whole cord, ventral column (VC), lateral column (LC), dorsal column (DC) and grey matter (GM). C2 C2/3 C3 C3/4 C4 C4/5 C5 C5/6 C6 C6/7 C7 Whole 0.716 0.722 0.681 0.666 0.692 0.683 0.656 0.641 0.649 0.645 0.648 Cord ±0.080 ±0.073 ±0.071 ±0.075 ±0.076 ±0.075 ±0.067 ±0.073 ±0.076 ±0.066 ±0.075 0.747 0.760 0.701 0.684 0.731 0.710 0.673 0.647 0.673 0.662 0.591 VC ±0.132 ±0.135 ±0.140 ±0.117 ±0.137 ±0.133 ±0.133 ±0.128 ±0.156 ±0.121 ±0.100

0.784 0.782 0.747 0.735 0.778 0.771 0.750 0.734 0.742 0.737 0.744 LC ±0.092 ±0.086 ±0.100 ±0.100 ±0.083 ±0.088 ±0.080 ±0.093 ±0.091 ±0.085 ±0.094

0.780 0.796 0.774 0.742 0.812 0.794 0.781 0.754 0.770 0.746 0.791 DC ±0.083 ±0.092 ±0.098 ±0.101 ±0.079 ±0.078 ±0.098 ±0.097 ±0.107 ±0.084 ±0.115

0.492 0.488 0.440 0.435 0.420 0.421 0.384 0.412 0.412 0.480 0.533 GM ±0.103 ±0.101 ±0.105 ±0.118 ±0.120 ±0.120 ±0.103 ±0.102 ±0.105 ±0.100 ±0.106

Table 2. Mean with standard deviation of mean diffusivity (MD) value in whole cord, ventral column (VC), lateral column (LC), dorsal column (DC) and grey matter (GM). C2 C2/3 C3 C3/4 C4 C4/5 C5 C5/6 C6 C6/7 C7 Whole 1.003 1.022 1.060 1.094 1.021 1.032 1.071 1.071 1.038 1.052 1.129 Cord(10-3) ±0.119 ±0.155 ±0.156 ±0.211 ±0.188 ±0.183 ±0.188 ±0.204 ±0.202 ±0.168 ±0.232 0.887 0.900 1.010 1.063 1.013 1.021 1.126 1.175 1.048 1.045 1.218 VC(10-3) ±0.235 ±0.290 ±0.320 ±0.357 ±0.424 ±0.344 ±0.397 ±0.345 ±0.391 ±0.354 ±0.345

0.998 1.025 1.077 1.109 1.030 1.027 1.062 1.091 1.046 1.043 1.096 LC(10-3) ±0.176 ±0.210 ±0.270 ±0.291 ±0.293 ±0.251 ±0.240 ±0.280 ±0.243 ±0.277 ±0.307

1.027 1.021 1.049 1.136 0.968 0.998 0.983 1.046 0.974 1.009 0.962 DC(10-3) ±0.176 ±0.250 ±0.274 ±0.318 ±0.245 ±0.242 ±0.237 ±0.316 ±0.273 ±0.193 ±0.289

1.043 1.086 1.110 1.082 1.057 1.008 1.062 1.005 1.029 1.035 1.095 GM(10-3) ±0.149 ±0.164 ±0.152 ±0.211 ±0.212 ±0.204 ±0.209 ±0.179 ±0.149 ±0.180 ±0.196

Table 3. Mean with standard deviation of radial diffusivity (RD) value in whole cord, ventral column (VC), lateral column (LC), dorsal column (DC) and grey matter (GM). C2 C2/3 C3 C3/4 C4 C4/5 C5 C5/6 C6 C6/7 C7 Whole 0.508 0.517 0.572 0.616 0.544 0.558 0.610 0.622 0.601 0.610 0.655 Cord(10-3) ±0.149 ±0.163 ±0.166 ±0.202 ±0.187 ±0.183 ±0.172 ±0.184 ±0.194 ±0.159 ±0.203 0.424 0.426 0.543 0.593 0.520 0.538 0.638 0.688 0.596 0.598 0.762 VC(10-3) ±0.227 ±0.288 ±0.306 ±0.327 ±0.352 ±0.315 ±0.342 ±0.305 ±0.349 ±0.311 ±0.281

0.430 0.461 0.525 0.555 0.465 0.469 0.508 0.541 0.513 0.519 0.538 LC(10-3) ±0.189 ±0.216 ±0.262 ±0.292 ±0.265 ±0.242 ±0.213 ±0.249 ±0.229 ±0.255 ±0.268

0.440 0.428 0.471 0.553 0.384 0.418 0.429 0.491 0.440 0.477 0.407 DC(10-3) ±0.185 ±0.240 ±0.269 ±0.296 ±0.237 ±0.225 ±0.232 ±0.288 ±0.274 ±0.192 ±0.272

0.732 0.769 0.815 0.798 0.796 0.757 0.827 0.760 0.774 0.730 0.725 GM(10-3) ±0.157 ±0.173 ±0.166 ±0.202 ±0.211 ±0.201 ±0.201 ±0.160 ±0.130 ±0.154 ±0.158

Table 4. Mean with standard deviation of axial diffusivity (AD) value in whole cord, ventral column (VC), lateral column (LC), dorsal column (DC) and grey matter (GM). C2 C2/3 C3 C3/4 C4 C4/5 C5 C5/6 C6 C6/7 C7 Whole 1.994 2.033 2.024 2.050 1.975 1.981 1.993 1.971 1.912 1.937 2.075 Cord(10-3) ±0.183 ±0.215 ±0.173 ±0.282 ±0.260 ±0.246 ±0.277 ±0.309 ±0.266 ±0.248 ±0.372 1.813 1.847 1.945 2.003 1.998 1.987 2.102 2.149 1.951 1.939 2.131 VC(10-3) ±0.411 ±0.415 ±0.416 ±0.485 ±0.681 ±0.528 ±0.615 ±0.540 ±0.578 ±0.528 ±0.572

2.132 2.152 2.180 2.217 2.159 2.144 2.170 2.190 2.111 2.089 2.212 LC(10-3) ±0.286 ±0.280 ±0.344 ±0.360 ±0.429 ±0.339 ±0.364 ±0.425 ±0.372 ±0.404 ±0.488

2.220 2.206 2.204 2.302 2.135 2.159 2.091 2.154 2.043 2.074 2.073 DC(10-3) ±0.258 ±0.349 ±0.338 ±0.426 ±0.319 ±0.329 ±0.336 ±0.430 ±0.338 ±0.271 ±0.413

1.666 1.721 1.699 1.650 1.581 1.511 1.533 1.496 1.537 1.645 1.836 GM(10-3) ±0.250 ±0.246 ±0.235 ±0.332 ±0.309 ±0.300 ±0.290 ±0.299 ±0.287 ±0.315 ±0.397 Appendix II:

Fig. 1 MD value distribution from C2 to C7 spinal segments in whole cord (A), ventral column (B), lateral column (C), dorsal column (D) and grey matter (E).

Fig. 2 RD value distribution from C2 to C7 spinal segments in whole cord (A), ventral column (B), lateral column (C), dorsal column (D) and grey matter (E). Fig. 3 AD value distribution from C2 to C7 spinal segments in whole cord (A), ventral column (B), lateral column (C), dorsal column (D) and grey matter (E). Appendix III:

Fig. 4 Correlation between age and mean diffusivity (MD) value in whole cord (A), ventral column (B), lateral column (C), dorsal column (D) and grey matter (E).

Fig. 5 Correlation between age and radical diffusivity (RD) value in whole cord (A), ventral column (B), lateral column (C), dorsal column (D) and grey matter (E). Fig. 6 Correlation between age and axial diffusivity (AD) value in whole cord (A), ventral column (B), lateral column (C), dorsal column (D) and grey matter (E).