Pileup of Remnant Orf1-Orf2 Element (PCR Fragment Jhp959+Jhp962)

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Pileup of Remnant Orf1-Orf2 Element (PCR Fragment Jhp959+Jhp962)

1 50 Lith10 aactcttatg cgatggtggt atcaataaat acgatttaag ttgcgggggc SpainB84 aactcttatg cgatggtggt atcaataaat acgatctaac atgtgcgggt Lith11 aactcttatg cgatggcggt atcaataaat acgatttaac atgtggggga SpainB50 aactcttatg cgatggcggt atcaataagt atgatttaac atgcgcgggc J99 aactcttatg cgatggcggt atcaataggt ataatctctc ttgtgcgggt India27 aactcttatg cgatggcggt atcaataagt atggcttaag ctgtgcgggt

51 100 Lith10 ttaactgcta acttattagc cgataatctt tggtcttatg gtttgcgaga SpainB84 ttaaccccta acttattagc cgataatctt tggtcttatg gtttgcgaga Lith11 ttaactgcta acttattagc caacaatctt tggtcttatg ggttgcgaga SpainB50 ttaactgcta atttattagc cgataatctt tggtcttatg gactacgaga J99 cttaccgaaa atttgctaaa agacattgag gtaaatctcg gtttagcgac India27 cttactgaaa atctgttaaa agatattttc aataatattg gactagcaac

101 150 Lith10 tgaggagtat gatgaagagg gtaatgtgat ...... taaa aaagaggcgg SpainB84 tgaggattat gatgatgagg gtaatgtgat ...... tgaa aaagaggcgg Lith11 tgaggattat gatgatgagg gcaatgtgat ...... tgaa aacgaggcgg SpainB50 tgaggactat gatgatgagg gtaatgttat cgagcctaaa aatgaaaacg J99 tcacgaggag gttgatgagt atattgata. ..acctggat aaagaggagg India27 tgctaaagag gttgatgagc atttagccga gttggataaa gaggaggcgg

151 200 Lith10 aggctgaaaa tttagaaaac taaacccccc ccagt..ggg gtggctctcc SpainB84 aggctgaaaa tttagaaaac taaactcccc ccctttgtga ggggtttcct Lith11 aggttgaaat tttagaaaac taaccccccc ...... t tgtggggtct SpainB50 agagcgaggt tgaaaactaa tcccccccct tttttttggg gtggctctcc J99 aagctgaaaa attagaaaac taaccgcccc caactctttt gggggtctcc India27 ag...... ttaaaagaa taaccccccc cttgtggggt ...... c

201 250 Lith10 ttttttttaa tctctctttt atttctttta ttttttcttt tttcattccc SpainB84 ttttttttaa tctctctttt atttctttta ttttttcttt tttcattccc Lith11 ccttttttaa tctctctttt att..ctttt atttttcttt ttccattccc SpainB50 ttttttaatc tctcttttct ttgctctctt atttttcttt tttcattccc J99 ttttttaatc tctcttttat ...... tctttgattt ttttattccc India27 tcctttttaa tctcttttat ...tctttta ttttttcttt tttcattccc

251 300 Lith10 tCTCTAATCT GTCCATTTAA TTTTGTTTAA AATATATTAT GTGTATAATC SpainB84 tCCCTAATCT GTCCATTTAA TTTTGTTTAA AATATATTAT GTGTATAATT Lith11 tCCCTAATCT GTCCATTTAA TTTTGTTTAA AATATATTAT GTGTATAATC SpainB50 tCCCTAACCT GTCCATTTAA TTTTGTTTAA AATATATTAT GTGTATAATC J99 tCTCTAACCT GTTAATTTAA TTTTGTTTAA AATATATTAT GTGTATAATC India27 tCCCTAATCT GTCAATTTAA TTTTGTTTAA AATATATTAT GTGTATAATC

301 350 Lith10 ATAAGAAATT TAATCAAAGG TAGTGCCATG CTTATAAACG CTGTCATAGA SpainB84 ATAAGAAATT CACTCAAAGG TAGTGCCATG CTTATAAACG CTGTCATAGA Lith11 ATAAGAAATT TAATCAAAGG TAGTGCCATG CTTATAAACG CTGTCATAGA SpainB50 ATAAGAAATT TAATCAAAGG TAGTGCCATG CTTATAAACG CTGTCATAGA J99 ATAAGAAATT TAATCAAAGG TAGTGCCATG CTTATAAACG CTGTCATAGA India27 ATAAGAAATT TAATCAAAGG TAGTGCCATG CTTATAAACG CTGTCATAGA

351 400 Lith10 AAAAGATGAG AATGGGTATT TTGCTTTTGT CCCCTTTCTA AAAGGCTGTG SpainB84 AAAAGATGAG AATGGGTATT TTGCTTTTGT CCCCTTTCTA AAAGGCTGTG Lith11 AAAAGATGAG AATGGGTATT TTGCTTTTGT CCCCTTTCTA AAAGGCTGTG SpainB50 AAAAGATGAG AATGGGTATT TTGCTTTTGT CCCCTTTCTA AAAGGCTGTG J99 AAAAGATGAG AATGGGTATT TTGCTTTTGT CCCCTTTCTA AAAGGCTGTG India27 AAAAGATGAG AATGGGTATT TTGCTTTTGT CCCCTTTCTA AAAGGCTGTG

401 450 Lith10 TATCACAAGG GAAAAGTTAT GAAGAAGCCC TAAGAAACAT TAAAGAAGCC SpainB84 TATCACAAGG GAAAAGTTAT GAAGAAGCCC TAAGAAACAT TAAAGAGGCC Lith11 TATCACAAGG GAAAAGTTAT GAAGAAGCCC TAAGAAACAT TAAAGAAGCC SpainB50 TATCACAAGG GAAAAGTTAT GAAGAAGCCC TAAGAAACAT TAAAGAAGCC J99 TATCACAAGG GAAAAGTTAT GAAGAAGCCC TAAGAAATAT TAAAGAAGCC India27 TATCACAAGG GAAAAGTTAT GAAGAAGCCC TAAGAAACAT TAAAGAAGCC

451 500 Lith10 ATAGAGCTTT ATTTGGGAGA TTTAGAAGCC GATGAGTTAG CTTTTCTTTC SpainB84 ATAGAGCTTT ATTTGGGAGA TTTAGAAGCC GATGAGTTAG CTTTTCTTTC Lith11 ATAGAGCTTT ATTTGGGAGA TTTAGAAGCC GATGAGTTAG CTTTTCTTTC SpainB50 ATAGAGCTTT ATTTGGGAGA TTTAGAAGCC GATGAGTTAG CTTTTCTTTC J99 ATAGAGCTTT ATTTGGGAGA TTTAGAAGCC GATGAGTTAG CTTTTCTCTC India27 ATAGAGCTTT ATTTGGGAGA TTTAGAAGCC GATGAGTTAG CTTTTCTTTC

501 550 Lith10 TAAGAAAAAT TCTGTAATAG CACCCATTGA GATAGCTTTT GCCTGAATTG SpainB84 TAATAAAAAT TCTGTAATAG CACCCATTGA GATAGCTTTT GCCTGAATTG Lith11 TAAGAAAAAT TCTGTAATAG CACCCATTGA GATAGCTTTT GCCTGAATTG SpainB50 TAAGAAAAAT TCTGTAATAG CACCCATTGA GATAGCTTTT GCCTGAATTG J99 TAAGAAAAAT TCTGTAATAG CACCCATTGA GATAGCTTTT GCCTGAATTG India27 TAAGAAAAAT TCTGTAATAG CACCCATTGA GATAGCTTTT GCCTGAATTG

551 600 Lith10 CCACGACTCA CAGCTAAAGA AGCAGAGAAG CTATTATTGC AGAATGGATT SpainB84 CCACGACTCA CAGCTAAAGA AGCAGAGAAG CTATTATTGC AGAATGGATT Lith11 CCACGACTCA CAGCTAAAGA AGCAGAGAAG CTATTATTGC AGAATGGATT SpainB50 CCACGACTCA CAGCTAAAGA AGCAGAGAAG CTATTATTGC AGAATTGATT J99 CCACGACTCA CAGCTAAAGA AGCAGAGAAA CTATTATTGC AGAATGGATT India27 CCACGACTCA CAGCTAAAGA AGCAGAGAAG CTATTATTGC AGAATGGATT

601 650 Lith10 TATTTTCTCT AGGCAAAAAG GCAGCCATAG AATTTATGTG AAAGATAAAA SpainB84 TGTTTTCTCT AGGCAAAAAG GCAGCCATAG AATTTATGTG AAAGATAAAA Lith11 TGTTTTCTCT AGGCAAAAAG GCAGCCATAG AATTTATGTG AAAGATAAAA SpainB50 TGTTTTCTCT AGGCAAAAAG GCAGCCATAG AATTTATGTG AAAGATAAAA J99 TGTTTTCTCT AGGCAAAAAG GTAGCCATAG AATTTATGTG AAAGATAAAA India27 TGTTTTCTCT AGGCAAAAAG GCAGCCATAG AATTTATGTG AAAGATAAAA

651 700 Lith10 TCAGGCAGGT TTTGCCTTTT CATTCTAGCG AAATCTTGCA CCCTAAAATA SpainB84 TCAGGCAGGT TTTGCCTTTT CATTCTGGCG AAATCTTGCA CCCCAAAATA Lith11 TCAGGCAGGT TTTGCCTTTT CATTCTAGCG AAATCTTGCA CCCTAAAATA SpainB50 TCAGGCAGGT TTTGCCTTTT CATTCTGGCG AAATCTTGCA CCCTAAAATA J99 TCAGGCAGGT TTTGCCTTTT CATTCTGGCG AAATCTTGCA CCCTAAAATA India27 TCAGGCAGGT TTTGCCTTTT CATTCTGGCG AAATCTTGCA CCCTAAAATA

701 750 Lith10 GTGAAAGAAA TCATGGAAAA TATCCTTAAA TGAAATCT.A AAGAAGTCTT SpainB84 GTGAAAGAAA TCATGGAAAA TATCCTTAAA TGAAATCT.A AAGAAGTCTT Lith11 GTGAAAGAAA TCATGGAAAA TATCCTTAAA TGAAATCT.A AAGAAATCTT SpainB50 GTGAAAGAAA TCATGGAAAA TATCCTTAAA TGAAATCTCA AAGAAGTCTT J99 GTGAAAGAAA TCATGGAAAA TACCCTTAAA TGAAGTCT.A AAGAAGTCTT India27 GTGAAAGAAA TCATGGAAAA TATCCTTAAA TGAAATCT.A AAGAAGTCTT

751 800 Lith10 AAAGATCTTA AACAATATaa aaacccaaca aaaagcgttt ttagtgggtt SpainB84 AAAGATCTTA AACAATATaa aaacccaaca aaaagcgttt ttagtgggtt Lith11 AAAGATCTTA AACAATATaa aaacccaaca aaaagcgttt ttagtgggtt SpainB50 AAAGATCTCA AACAATATaa aaacccaaca aaaagcgttt ttagtgggtt J99 AAAGATCTCA AACAATATaa aaacccaaca aaaagcgttt ttagtgggtt India27 AAAGATCTTA AACAATATaa aaacccaaca aaaagcgttt ttagtgggtt

801 Lith10 tttgcgttta SpainB84 tttgcgttta Lith11 tttgcgttta SpainB50 tttgcgttta J99 tttgcgttta India27 tttgcgttta

Figure S1. Pileup of the orf1-2 remnant (PCR fragment jhp959+jhp962). Upper case represents sequence of orf1-2 remnant. Underline represents termination codon of jhp959. Last three nucleotides in all sequences are termination codon of jhp962 (reverse). 1 70 Chen4 (1) GCGGTATCAATAAATACGGCTTAAGCTGTGCGGGTCTTACCGAAAACTTGTTAAAAGACATTTTTAATAA HP1024 (1) GCGGCATCAATAAATACGGCTTAAGTTGTGCGGGTCTTACCGAAAATTTATTAAAAGATGTTGAATTAAC HP1031 (1) GCGGTATCAATAAATACGGATTAAGCTGTGCGGGTCTTACCGAAAATCTGTTAAAAGACATTGAGCTTTC HP1032 (1) GCGGTATCAATAAATACGGCTTAAGTTGTGCGGGTCTTACCGAAAATCTGTTAAAAGATATTGAGCCTGC HP1034 (1) GCGGTATCAATAAATATGATTTAACATGCACGGGTCTTACCGAAAATTTATTAAAAGATGTTGAATTAAC I-44 (1) GCGGTATCAATAAATACGGCTTAAGCTGTGCGGGTCTTACTGAAAATTTGTTAAAAGGCATTTTTAATAA I-48 (1) GCGGTATCAATAAATACGGCTTAAGCTGTGCGGGTCTTACTGAAAATCTGTTAAAAGATATTGAGGTAAA I-77 (1) GCGGTATCAATAAGTATAATCTTTCATGTGGCGGTTTAACTAAAAATTTGTTAAACGATTTTACGCCTTA PeCan1 (1) GTGGTATCAACAAATACGACTTAACTTGTGCGGGCTTAACCCCTAACTTATTAGCCGAT--AATCT---- PeCan18B (1) GTGGTATCAATAAGTATGATTTAACTTGTACGGGCTTAACCCCTAACTTATTAGCCGAT--AATCT---- PeCan9 (1) GCGGTATCAATAAATACGGATTAAGCTGTGCGGGTCTTACCGAAAATCTGTTAAAAGATATTTTCAATAA SpB43 (1) GCGGTATCAATAAATATGGCTTAAGCTGTGCGGGTCTTACTGAAAATCTGTTAAAAGACGTTGAACCTAA SpB63 (1) GCGGTATCAATAGGTATAATCTCTCTTGTGCGGGTCTTACTGAAAATTTACTAAACGATGTAATCCCGCA SpB71 (1) GCGGTATCAATAAATACGATTTAACATGTGGGGGATTAACTGCTAACTTATTAGCCGAC--AATCT---- SpB76 (1) GCGGTATCAATAGATATGATTTAAGTTGTGCGGGCTTAACTGCTAACTTATTAGCCGAC--AATCT---- Consensus (1) GCGGTATCAATAAATACGG TTAAG TGTGCGGGTCTTACCGAAAATTTGTTAAAAGAT TT T 71 140 Chen4 (71) TATCGGTTTAGCAAATGTTAAAGAAGT--TGATGAGCATTTAGCTAATTTAGA------TA HP1024 (71) TTTTGGTTTAGCGACCCCTAGTGAGAT--TGATGAGTATCTCGCTAATTTAGA------TA HP1031 (71) CTTTGGTTTAGCGACCCCTAGTGAGAT--TGATGAGTATCTCGCTAATTTAGA------AA HP1032 (71) CTTTGGTCTAGCAACGCATGCGGAGGT--TGATGAGGAGTTAGCAAAATTGGA------AA HP1034 (71) TTTTGGTTTAGCGACCCCTAGTGAGAT--TGATGAGTATCTTGATATTTTAGA------TA I-44 (71) TATCGGTTTAGCAAATGTTAAAGAGGT--TGATGAGCATCTTGTTAATTTAGA------TA I-48 (71) TCTTGGTTTAGCAACGCATGAGGAGAT--TGATGAGTATTTTGCTAATTTAGA------AA I-77 (71) TATGGGGCTTATGGACCAAGAGTCG-----CTTGATGCGTTTTTAGAGGAGGA------AAATG---- PeCan1 (65) --TGGGGGTTATGGACTACGAGATGAGGGCGATGAGGATTTAGATAAAG----CG------PeCan18B (65) --TTGGTCTTATGGATTGCGAGATGAGGATTATGATGATGAGGGTAATGTTATCGAGTCTAAAAATGAAA PeCan9 (71) TATTGGACTAGCAACTGCTAAAGAGGT--TGATGAGCACCTTGCTAATTTAGA------CA SpB43 (71) TTTCGGTTTAGCGACTAATAAAGAGAT--TGATGAGTATCTCGCTAATTTAGA------TA SpB63 (71) TATTGGGCTAGAGGCTGATGAGAAGT--ATCTTAAAGAATTGGACAAGGATGAGG------AATTGTCTA SpB71 (65) --TTGGTCTTATGGGTTGCGAGATGAGGATTATGATGAGAAGGGTAATGTGATTAAGGAGAGGGATATTG SpB76 (65) --TGGTTATTATGGGTTGTTAACTA------ATAGCGACTTATCAAATGAAAACG------Consensus (71) T TTGGT TAGCGACT T A GAGAT TGATGAG AT T GCTAATTTAGA A 141 210 Chen4 (124) AAGAGGAGGCGGAG------TTAAA-----AGAA TA ACCCCCCCC----TTGT-GGGG---T- HP1024 (124) AGGAGGGAGAGGT------AGA------A TA GCCCCCC------ATGTGGGGT---GG HP1031 (124) AAGAGGGAGAGGT------AAA------A TA ACCCCCCCCCTATAAGAAGGGT---GG HP1032 (124) AAGAGGGAGAGAT------AGA------A TA ACCCCCCC-----ATGTGGGGT---GG HP1034 (124) AGGAGGAGAAGAGAG------T-AGA------A TA ACCCCCC------ATGTGGGGT---GG I-44 (124) AAGAGGAGGCGGAG------TTAAA-----AGAA TA ACCCCCCCT----ATGG-GGGG---GT I-48 (124) AAGAGGAGAGTGAAAG------CGCTTCCAT-TGTAGAA TA ACTCCCCCC----ATGTGGAGT---GG I-77 (124) ---AGGGCGAGGC------TGAAAATTTAGAAA------AC TA ACC---CCCCCA--TGTGGGGT---GG PeCan1 (114) --GAGGCGGAGACTGAAAAT-----TTAGAAA------AC TA ACCGCCCCCAAC--TCTTTTG---GGG PeCan18B (133) ACGAGGGCGAGGCTGAAAATACTACTTTTAAAGAGGAGGAA TA AACTCCCCCCAC--TCTCTTGTGAGGG PeCan9 (124) AAGAGGAGGCGGAG------TTAAA-----AGAA TA ACCCTTATG----GGGGAGGGG---GT SpB43 (124) AAGAGGAGGCGGAG------TTAAA-----AGAA TA ACCCCCCCC----CCTAGTGGG---GT SpB63 (133) AAAACTCCGATGAGTGGTTTGCTAGTTTGAAAA------AC TA ACCTCCCCCCCA--TGTGGGGT---AG SpB71 (133) TTACGGGAGAGGAGTTAAATAATGCGGAGGGTAATGTAGAA TA AACCCCCCCCCC--ACTCCTAGTGGGG SpB76 (112) ---AGAGCGAGGCTGAAAATACCACCTTTAAAGAGGGGGAA TA AACCCCCCCCA---TGTGGGGT---GG Consensus (141) AAGAGG GAGG T AAA GAATAACCCCCCCC TGTGGGGT GG 211 280 Chen4 (167) --CTCCTTTTTTTT------HP1024 (161) CTCT-TTTTT------TCTC------TCTT------A----TTTTTCTTTTTTCA HP1031 (167) CTCTCTTTTATTTTTTTCTCTCTTATTCTC------TCTTTTAT-CCTCTTA----TTTTTCTTTTT-CA HP1032 (162) CTCCCTTTTTCTTT-----CTTTTATTCTC------TCTT------A----TTTTTCTTTT---A HP1034 (164) CTCTCTTTTTTTAATCTCTTATTTTTTTTC------TCTT------A----TTTTTCTTTT---A I-44 (168) GGCTCTCTTTTTTT------I-48 (178) CTCTCCTTTTTTTAATCTCCTTTTATTTTA------GTTTTCTT-G---TAT----CATAAGCGTTATAA I-77 (171) CTCTCCTTTTTTT-AATCTCT-CTTTTATT----TCTCTTTTAT-TCTTTTATCGTTATAAGTGGCTA-- PeCan1 (165) GTCTCCTTTTTTTTAATCTTTTCTTTTATT------CTTTTAT--TTCTTTTTCTTTTTTCTTGTGTCG PeCan18B (201) GTCTCCTTTTTT--AATCTCT-CTTTTATT------CTTTTCT--TTCT------TTTTTCTTGTGTCG PeCan9 (169) GGCTCTCTTTTTTTAATCTCTTATTTTTCT------TTTTTT------A SpB43 (169) GGCTCTCCTTTTTTAATCTCTTTTATTTTT------CTTTTTCT-T---CT------A SpB63 (192) CTCTCCTTTTTTTTAATCTCT-CTTTTATTCTCTTATCTTGTATCTTTTTTATGTTGTTTTCTTGCTTGC SpB71 (201) TGGCTCTTTTTTTTAATCTCT-CTTTTATT------TTTTAT--TCTTTA----GTTTTCTTGTATC- SpB76 (173) CTCTCCTTTTTT--AATCTCT-CTT---TT------CTTTGCT--CTCTTA----TTTTTCTTTTTTCA Consensus (211) CTCTCCTTTTTTTTAATCTCT TTTT TT CTTTT T T A TTTTTCTT T A 281 350 Chen4 (179) ------TA-ATC--TCTTTTAT------HP1024 (193) TTGATTT-----A----ATAGC-----GATTC-AAAGGTCGTTTGA------HP1031 (225) TTGATTG-----A-----TAGC-----GAT------GCCGTTTGA------HP1032 (203) TTGATTG-----A-----TAGC-----GATTA-AA--GTCGTTTAA------HP1034 (210) TTGATTG-----G-----TAGC-----GATTA-AAG--CCGTTTAA------I-44 (182) ------TA-AT---TCTTTTAT------I-48 (234) TTGATTT-----A-----TAGC-----GATTA-AAG--TCGTTTAA------I-77 (232) -TAAATCAATTCACACGCTCTTTTATTGATTAGTAAGGTTTTCTATTGATTAAAGTTAAAAA-GCGTTAT PeCan1 (226) TTGTTTTAGTTTTACTGCTCTCATTTTAGTTTTAATGCTCTTTTAT------A------PeCan18B (253) TTGTTTTAGTTTTACTGCTCTCATTTTAGTTTTAACGCTCTTTTAT------A------PeCan9 (206) TGGATTT-----A-----TAGC-----GATTA-AGG--TCGTTTAA------SpB43 (211) TTGATTT-----A-----TAGC-----GATTA-AAG--CCGTTTAA------SpB63 (261) TTATTTTAGTTTAAACGCTCTTTTATTGATTAGTAAG-TTTTCTATTGATTAAAGTTAAAAAAGCGTTTA SpB71 (255) --ATAAGCGTTATAATTGATTTATAGCGATTA--AAGCCGTT-TAA------SpB76 (224) TTCTTTT------CTTGTATC------GTTAGAATGC-----TAT------A------Consensus (281) TTGATTT A TA C GATTA AA TC TTTAA 351 418 Chen4 (192) ------AGCGTTCTTTTAAGAAATCGTGCGCAGATACCCGTTTTCGCTCAGCATGACATACA HP1024 (224) -ATCCATTGAT-AGCGCTCT-TTAAGAAATCGTGCGCAGATACCCGTTTTCGCTCAGCATGACATACA HP1031 (249) -ATCCATTGAT-AGCGCTCT-TTAAGAAATCGTGCGCAAATACCCGTTTTCGCTCAGCATGACATACA HP1032 (231) -ATCCATTGAT-AGCGCTCT-TTAAGAAATCGTGCGCAGATACCCGTTTTCGCTCAGCATGACATACA HP1034 (238) -ATCCATTGAT-AGCGCTCT-TTAAGAAATCGTGCGCAGATACCCGTTTTCGCTCAGCATGACATACA I-44 (194) -TAGTTTTATTAAAAGGTCTTTTAAGAAATCGTACGCAAATACCCGTTTTCGCTCAGCATGACATACA I-48 (262) -ATCCATTTAT-AGTGCTCTTTTAAGAAATCGTGCGCAGATACCCGTTTTCGCTCAGCATGACATACA I-77 (300) AACCAATTTATA-GCGTTCTCTTAAGAAATCGTGCGCAAATACCCGTTTTCGCTCAGCATGACATACA PeCan1 (273) -ATCCGTTTATAAGCATTCTCTTAAGAAATCGTGCGCAAATACCCGTTTTCGCTCAGCATGACATACA PeCan18B (300) -ATCCATTTATA-GCGTTCTTTTAAGAAATCGTGCGCAAATACCCGTTTTCGCTCAGCATGACATACA PeCan9 (234) -ATCCATTTATAAGCATTCTCTTAAGAAATCGTGCGCAAATACCCGTTTTCGCTCAGCATGACATACA SpB43 (239) -ATCCATTTATAAGCATTCTCTTAAGAAATCGTGCGCAAATACCCGTTTTCGCTCAGCATGACATACA SpB63 (330) AATCAATTTATA-GCGTTCTTTTAAGAAATCGTGCGCAAATACCCGTTTTCGCTCAGCATGACATACA SpB71 (296) -ATCCATTTATA-GTACTCTTTTAAGAAATCGTGCGCAAATACCCGTTTTCGCTCAGCATGACATACA SpB76 (253) -ACCAATTTATA-GCGTTCTTTTAAGAAATCGTGCGCAAATAACCGTTTTCGCTCAGCATGACATACA Consensus (351) ATCCATTTATAAGCGTTCT TTAAGAAATCGTGCGCAAATACCCGTTTTCGCTCAGCATGACATACA

Figure S2.

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