Infection Outcomes in Rheumatoid Arthritis Patients Switching Anti-TNF Agents

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Infection Outcomes in Rheumatoid Arthritis Patients Switching Anti-TNF Agents

The D EGGE GROUP, LTD Drug Safety Research and Information

Appendices

Risk of Significant Infection in Rheumatoid Arthritis Patients Switching Anti-Tumor Necrosis Factor- Drugs

1616 North Fort Myer Drive, Suite 1430 Arlington, Virginia 22209-3100 Office (703) 276-0067 Fax (703) 276-0069 Table of Appendices

APPENDIX A. Serious Infectious Diseases...... 2

APPENDIX B. Infectious Conditions...... 6

APPENDIX C. J-Codes for Intravenous Antimicrobial Treatment...... 8

APPENDIX D. List of Intravenous Antibiotics...... 8

APPENDIX E. Procedural Codes for Joint Surgery in RA Patients...... 11

APPENDIX F. List of DMARDS...... 26

APPENDIX G. J-Codes for DMARDS Used for Rheumatoid Arthritis Treatment...... 26

APPENDIX H. List of Oral Corticosteroids...... 27

APPENDIX I. List of Antidiabetic Drugs...... 28

APPENDIX J. List of Medications to Treat Asthma/COPD...... 29

The Degge Group, Ltd. A - 1 aTNF Switching Study 04/06/2018 APPENDIX A. Serious Infectious Diseases Defined by Hospitalization or Requiring Intravenous Antibiotics

ICD-9-CM Code Category / Code Description

001-009 Intestinal infectious diseases 001 Cholera 002 Typhoid and paratyphoid fevers 003 Other salmonella infections 004 Shigellosis 005 Other food poisoning (bacterial) 006 Amebiasis 007 Other protozoal intestinal disease 008 Intestinal infections other organisms 009 Ill-defined intestinal infections 010-018 Tuberculosis* 010 Primary tuberculous infection* 011 Pulmonary tuberculosis* 012 Other respiratory tuberculosis* 013 Tuberculosis of meninges and CNS* 014 TB intestine/peritoneum/mesenteric* 015 Tuberculosis of bones and joints* 016 TB of genitourinary system* 017 Tuberculosis of other organs* 018 Miliary tuberculosis* 020-027 Zoonotic bacterial diseases 020 Plague 021 Tularemia 022 Anthrax 023 Brucellosis 024 Glanders 025 Melioidosis 026 Rat-bite fever 027 Other zoonotic bacterial diseases 030-041 Other bacterial diseases 030 Leprosy* 031 Diseases due to other mycobacteria* 032 Diphtheria* 033 Whooping cough* 034 Strep sore throat and scarlet fever 035 Erysipelas 036 Meningococcal infection* 037 Tetanus* 038 Septicemia 039 Actinomycotic infections 040 Other bacterial diseases 041 Bacterial infection in other conditions 042 Human Immunodeficiency Virus

The Degge Group, Ltd. 2 aTNF Switching Study 04/06/2018 ICD-9-CM Code Category / Code Description

042 Human immunodeficiency virus disease (HIV) 045-049 Poliomyelitis/other non-arthropod viral diseases of CNS* 045 Acute poliomyelitis* 046 Slow virus infection of CNS* 047 Meningitis due to enterovirus* 048 Other enterovirus diseases of central nervous system* 049 Other viral diseases of CNS* 050-057 Viral diseases accompanied by exanthem 050 Smallpox 051 Cowpox and paravaccinia 052 Chickenpox 053 Herpes zoster 054 Herpes simplex 055 Measles 056 Rubella 057 Other viral exanthemata 060-066 Arthropod-borne viral diseases 060 Yellow fever 061 Denge 062 Mosquito-borne viral encephalitis 063 Tick-borne viral encephalitis 064 Viral encephalitis transmitted by unspecified arthropods 065 Arthropod-borne hemorrhagic fever 066 Other arthropod-borne viral diseases 070-079 Other diseases due to viruses & chlamydiae 070 Viral hepatitis* 071 Rabies 072 Mumps 073 Ornithosis 074 Diseases due to coxsackie virus 075 Infectious mononucleosis 076 Trachoma 077 Other conjunctiva disease virus/chlamidae 078 Other disease virus/chlamidiae 079 Viral/chlamydial infection 080-088 Rickettsioses & other arthropod-borne diseases 080 Louse-borne (epidemic) typhus 081 Other typhus 082 Tick-borne rickettsioses 083 Other rickettsioses 084 Malaria 085 Leishmaniasis 086 Trypanosomiasis 087 Relapsing fever 088 Other arthropod-borne diseases 090-099 Syphilis & other venereal diseases* 090 Congenital syphilis* 091 Early syphilis symptomatic*

The Degge Group, Ltd. 3 aTNF Switching Study 04/06/2018 ICD-9-CM Code Category / Code Description

092 Early syphilis latent* 093 Cardiovascular syphilis* 094 Neurosyphilis* 095 Other late syphilis with symptoms* 096 Late syphilis, latent* 097 Other and unspecified syphilis* 098 Gonococcal infections* 099 Other venereal diseases* 100-104 Other spirochetal diseases 100 Leptospirosis 101 Vincent's angina 102 Yaws 103 Pinta 104 Other spirochetal infection 110-118 Mycoses* 110 Dermatophytosis* 111 Other/unspecified dermatophytosis* 112 Candidiasis* 114 Coccidioidomycosis* 115 Histoplasmosis* 116 Blastomycotic infection* 117 Other mycoses* 118 Opportunistic mycoses* 120-129 Helminthiases 120 Schistosomiasis (bilharziasis) 121 Other trematode infections 122 Echinococcosis 123 Other cestode infection 124 Trichinosis 125 Filarial infection/dracontiasis 126 Ancylostomiasis and necatoriasis 127 Other intestinal helminthiases 128 Other/unspecified helminthiases 129 Intestinal parasitism, unspecified 130-136 Other infectious & parasitic diseases 130 Toxoplasmosis 131 Trichomoniasis 132 Pediculosis/phthirus infestation 133 Acariasis 134 Other infestation 135 Sarcoidosis 136 Other/unspecified infectious/parasitic disorder

137-139 Late effects of infectious & parasitic diseases 137 Late effects of tuberculosis 138 Late effects of acute poliomyelitis 139 Late effect infect/parasitic disease

The Degge Group, Ltd. 4 aTNF Switching Study 04/06/2018 * Selected conditions chosen to represent serious infections regardless of hospitalization or IV antibiotic administration.

International Classification of Diseases, Ninth Revision, Clinical Modification. 9th ed. Washington, DC: US Department of Health and Human Services, Centers for Disease Control and Prevention, Centers for Medicare and Medicaid Services; 2007.

The Degge Group, Ltd. 5 aTNF Switching Study 04/06/2018 APPENDIX B. Infectious Conditions Requiring Hospitalization or Intravenous Antibiotics

ICD-9 Code Code Description 254.1 Abscess of thymus 255.8 Oth disorders of adrenal gland - cortisol-binding globulin abnormality (for abscess) 323.x Encephalitis, myelitis, and encephalomyelitis 324.x Intracranial and intraspinal abscess 357.0 Acute infective polyneuritis 380.1 Infective otitis externa 382.0 Acute suppurative otitis media 382.9 Unspecified otitis media 383.x Mastoiditis and related conditions 384.0 Acute myringitis without mention of otitis media 384.1 Chronic myringitis without mention of otitis media 421.x Acute and subacute endocarditis 422.x Acute myocarditis 424.9 Endocarditis, valve unspecified 447.2 Rupture of artery (for artery ascess) 457.2 Lymphangitis 460 Acute nasopharyngitis [common cold] 461.x Acute sinusitis 462 Acute pharyngitis 463 Acute tonsilitis 464.x Acute laryngitis and tracheitis 465.x Acute upper respiratory infections of multiple or unspecified sites 466.x Acute bronchitis and bronchiolitis 472 Chronic pharyngitis and nasopharyngitis 473.x Chronic sinusitis 474.0 Chronic tonsilitis 475 Peritonsillar abscess 476.x Chronic laryngitis and laryngotracheitis 480 Viral pneumonia 481 Pneumococcal pneumonia 482 Other bacterial pneumonia 483 Pneumonia due to other specified organism 484 Pneumonia in infectious diseases classified elsewhere 485 Bronchopneumonia, organism unspecified 486 Pneumonia, organism unspecified 487.1 Influenza with other respiratory manifestations 487.8 Influenza with other manifestations 490 Bronchitis, not specified as acute or chronic 491.2 Obstructive chronic bronchitis 510.x Empyema 511.1 Pleurisy with effusion, with mention of a bacterial cause other than tuberculosis 513.x Abscess of lung and mediastinum 519.1 Other diseases of trachea and bronchus, NEC (for bronchial abscess) 519.2 Mediastinitis 522.5 Periapical abscess without sinus 522.7 Periapical abscess with sinus 523.3 Acute periodontitis 528.3 Cellulitis and abscess of oral soft tissues 528.5 Diseases of the lips (for labial abscess) 529.0 Glossitis 540-542 Appendicitis

The Degge Group, Ltd. 6 aTNF Switching Study 04/06/2018 ICD-9 Code Code Description 550.0 Inguinal hernia, with gangrene 551.x Other hernia of abdominal cavity, with gangrene 566 Abscess of anal and rectal regions 567.x Peritonitis 569.5 Abscess of intestine 572 Liver abscess and sequelae of chronic liver disease 572.0 Abscess of liver 572.1 Portal pyaemia 574.0 Calculus of gallbladder with acute cholecystitis 574.1 Calculus of gallbladder with other cholecystitis 574.3 Calculus of bile duct with acute cholecystitis 574.4 Calculus of bile duct with other cholecystitis 575.0 Acute cholecystitis 575.1 Other cholecystitis 576.1 Cholangitis 590.x Infections of kidney 595.x Cystitis 597.0 Urethral abscess 597.8 Other urethritis 599.0 Urinary tract infection, site not specified 603.1 Infected hydrocele 604.x Orchitis and epididymitis 607.1 Balanoposthitis 607.2 Other inflammatory disorders of penis 614.x Inflammatory disease of ovary, fallopian tube, pelvic cellular tissue and peritoneum 615.0 Acute inflammatory diseases of uterus, except cervix 615.9 Unspecified inflammatory diseases of uterus, except cervix 616.x Inflammatory disease of cervix, vagina, and vulva 680.x Carbuncle and furuncle 681.x Cellulitis and abscess of finger and toe 682.x Other cellulitis and abscess 684 Impetigo 685.0 Pilonidal cyst, without abcess 686.x Other local infections of skin and subcutaneous tissue 711.0 Pyogenic arthritis 711.9 Infectious arthritis 728.0 Infective myositis 729.4 Fasciitis, unspecified 730.x Osteomyelitis, periostitis, and other infections involving bone 785.4 Gangrene 788.7 Urethral discharge 790.7 Bacteremia, unspecified 790.8 Viremia, unspecified 996.6 Infection and inflammatory reaction due to internal prosthetic device, implant, graft 998.5 Postoperative infection 999.3 Complications of medical care, other infections

World Health Organization: Manual of the international statistical classification of diseases, injuries and causes of death. Ninth revision, Volume 1. Geneva, WHO 1977.

The Degge Group, Ltd. 7 aTNF Switching Study 04/06/2018 APPENDIX C. Medication Names Used to Define Intravenous Antibiotics*

Generic Name Generic Name Amikacin Erythromycin Lactobionate Ampicillin Gentamicin Ampicillin Sodium/Sulbactam Sodium Imipenem Azithromycin Imipenem-Cilastatin Aztreonam Kanamycin Capreomycin Levofloxacin Cefazolin Linezolid Cefepime Meropenem Cefotaxime Metronidazole Cefotetan Moxifloxacin Cefoxitin Nafcillin Ceftazidime Norfloxacin Ceftizoxime Ofloxacin Ceftriaxone Oxacillin Cefuroxime Piperacillin Cilastatin Piperacillin-Tazobactam Cilastatin Sodium/Imipenem Polymyxin B Sulfate/Trimethoprim Sulfate Ciprofloxacin Quinupristin Clavulanate Potassium Streptomycin Clindamycin Sulbactam Dalfopristin Sulfamethoxazole Dalfopristin-Quinupristin Sulfamethoxazole/Trimethoprim Daptomycin Tazobactam Sodium Dextrose Ticarcillin Ertapenem Sodium Tobramycin Erythromycin Trimethoprim Erythromycin Gluceptate Vancomycin

*NDC codes are not displayed due to the excessively large number of codes

The Degge Group, Ltd. 8 aTNF Switching Study 04/06/2018 APPENDIX D. Intravenous Antimicrobial Treatment J-Codes

J Code Code description J0120 Injection tetracycline up to 250 mg J0200 Inj alatrofloxacin mesylate 100 mg J0278 Injection, amikacin sulfate, 100 mg (2006) J0285 Injection amphotericin B 50 mg J0286 Injection amphotericin B 50 mg (2000) J0287 Infection amphotericin B lipid complex 10 mg (2006) J0288 Inj ampho B cholesteryl sulfate complex 10 mg (2006) J0290 Injection ampicillin sodium 500 mg J0295 Inj ampclln sodim/sulbactam-1.5 g J0456 Injection azithromycin 500 mg (2006) J0500 Injection dicyclomine hcl up 20 mg J0530 Inj pen G benzathine & pcn G procaine up to 600k u (2006) J0540 Inj pen G benzathine & pcn G procaine up to 1.2m u (2006) J0550 Inj pen G benzathine & pcn G procaineup to 2.4m u (2006) J0560 Inj pen G benzathine up to 600k u (2006) J0570 Injection pen G benzathine up to 2.4m u (2006) J0580 Inj penicillin G benzathine up to 2.4m u (2006) J0690 Injection cefazolin sodium 500 mg J0692 Inj cefepime hydrochloride 500 mg J0694 Injection cefoxitin sodium 1 g J0695 Cefonocid sodium injection (1998) J0696 Injection ceftriaxone sodium-250 mg J0697 Inj sterl cefuroxime sodium-750 mg J0698 Cefotaxime sodium per g J0710 Injection cephapirin sodium up 1 g J0713 Injection ceftazidime per 500 mg J0715 Injection ceftizoxime sodium-500 mg J0720 Inj chloramphenicol sodium succinate up to 1 g (2006) J0740 Injection cidofovir 375 mg J0743 Inj cilastatin sodim imipenem-250mg J0744 Inj ciprofloxacin for iv infusion 200 mg (2006) J0744 Inj ciprofloxacin iv infus 200 mg J0770 Injection colistimethate sodium up to 150 mg (2006) J0878 Injection daptomycin 1 mg (2006) J1335 Injection ertapenem sodium 500 mg (2006) J1362 Erythromycin glucep / 250 mg (1998) J1364 Injection erythromycin lactobionate 500 mg (2006) J1570 Injection ganciclovir sodium 500 mg J1580 Injection garamycin gent to 80 mg J1590 Injection gatifloxacin 10 mg (2006) J1840 Injection kanamycin sulfate up to 55 mg (2006) J1850 Inj kanamycin sulfate up 75 mg J1890 Injection cephalothin sodium to 1 g J1956 Injection levofloxacin 250 mg J2010 Injection lincomycin HCl to 300 mg J2020 Injection linezolid 200mg J2185 Injection meropenem 100 mg (2006)

The Degge Group, Ltd. 9 aTNF Switching Study 04/06/2018 J Code Code description J2280 Injection moxifloxacin 100 mg (2006) J2460 Inj oxytetracycline HCl up to 50 mg (2000) J2460 Injection oxytetracycline HCl up to 50 mg (2006) J2510 Inj penicillin G procaine aqueous up to 600 k u (2006) J2540 Injection pcn G K+ to 600000 units J2543 Inj pip/tz 1 gram/0.125 grams J2700 Inj oxacillin sodium to 250 mg J2770 Injection quinupristin/dalfopristin 500 mg (150/350) (2006) J3000 Injection streptomycin up to 1 g (2006) J3260 Inj tobramycin sulfate to 80 mg J3320 Inj spectinomycin dihydrochloride up to 2 g (2006) J3370 Injection vancomycin hcl 500 mg J3490 UCD-amikacin sulfate 50 mg (2006) J3490 UCD-aztreonam 500 mg (2006) J3490 UCD-cefotetan (2006) J3490 UCD-clavulanate potass ticarcillin disodium 0.1-3 g (2006) J3490 UCD-clindamycin phosphate 150 mg (2006) J3490 UCD-minocycline hcl 100 mg (2006) J3490 UCD-nafcillin sodium 1 g (2006) J3490 UCD-rifampin 600 mg (2006) S0016 Injection amikacin sulfate 500 mg (2000) S0017 Inj amikacin sulfate 500 mg (2000) S0024 Injection ciprofloxacin, 200mg S0032 Inj nafcillin sodium 2 g (2000) S0034 Inj ofloxacin 400 mg (2000) S0039 Inj sulfamethoxazole and trimethoprim 10 ml (2000) S0040 Inj ticarcilln & clavulanate K+31 gm S0072 Injection amikacin sulfate 100 mg S0073 Injection aztreonam 500 mg S0074 Injection cefotetan disodium 500 mg S0077 Inj clindamycin phosphate 300 mg S0081 Inj piperacillin sodium 500 mg (2000) S5017 Antibiotic administration supplies (without pump), per day S9494 Hit antibiotic/antifungal; diem S9500 Hit antibiotic/antifungal; Q24 hrs S9501 Hit antibiotic/antifungal; Q12 hrs S9502 Hit ABx antiviral/antifungal; Q8 hrs S9504 Hit ABx antiviral/antifungal; Q4 hrs S9539 Administration of antibiotics, intravenously

UCD -Unclassified drug.

The Degge Group, Ltd. 10 aTNF Switching Study 04/06/2018 APPENDIX E. List of ICD-9-CM Codes for Opportunistic Infections Dx Code Description 0030 Salmonella Gastroenteritis 004 Shigellosis 0040 Shigella Dysenteriae 0041 Shigella Flexneri 0042 Shigella Boydii 0043 Shigella Sonnei 0048 Other Shigella Infections 0049 Shigellosis Unspec 006 Amebiasis 0060 Acute Amebic Dysentery Wo Abscess 0061 Chron Intestin Amebiasis Wo Abscess 0062 Amebic Nondysenteric Colitis 0063 Amebic Liver Abscess 0064 Amebic Lung Abscess 0065 Amebic Brain Abscess 0066 Amebic Skin Ulceration 0068 Amebic Infection Other Sites 0069 Amebiasis Unspec 0072 Coccidiosis 0074 Cryptosporidiosis 0080 Intestinal Infection Due To E Coli 00843 Intestinal Infec Campylobacter 00849 Intestinal Infec Other Bacteria 0085 Uns Bacterial Enteritis 0088 Other arthropod-borne diseases 010 Primary Tuberculous Infection 0100 Primary Tuberculous Complex 01000 Primary Tuberculosis Complex Uns Exam 01001 Primary Tuberculosis Complex No Exam 01002 Primary Tuberculosis Complex Exam Unkn 01003 Primary Tuberculosis Complex Micro Dx 01004 Primary Tuberculosis Complex Cult Dx 01005 Primary Tuberculosis Complex Histo Dx 01006 Primary Tuberculosis Complex Other Test 01010 Tuberculosis Pleurisy Primary ProgTuberculosis Uns Exam 01011 Tuberculosis Pleurisy Primary ProgTuberculosis No Exam 01012 Tuberculosis Pleurisy Primary ProgTuberculosis Exam Unk 01013 Tuberculosis Pleurisy Primary ProgTuberculosis Micro Dx 01014 Tuberculosis Pleurisy Primary ProgTuberculosis Cult Dx 01015 Tuberculosis Pleurisy Primary ProgTuberculosis Histo Dx 01016 Tuberculosis Pleurisy Primary ProgTuberculosis Oth Test 01080 Oth Primary Progressive Tuberculosis Uns Exam 01081 Oth Primary Progressive Tuberculosis No Exam 01082 Oth Primary Progressive Tuberculosis Exam Unk 01083 Oth Primary Progressive Tuberculosis Micro Dx 01084 Oth Primary Progressive Tuberculosis Cult Dx 01085 Oth Primary Progressive Tuberculosis Histo Dx 01086 Oth Primary Progressive Tuberculosis Oth Test 01090 Uns Primary Tuberculosis Infection Uns Exam

The Degge Group, Ltd. 11 aTNF Switching Study 04/06/2018 01091 Uns Primary Tuberculosis Infection No Exam 01092 Uns Primary Tuberculosis Infection Exam Unkn 01093 Uns Primary Tuberculosis Infection Micro Dx 01094 Uns Primary Tuberculosis Infection Cult Dx 01095 Uns Primary Tuberculosis Infection Histo Dx 01096 Uns Primary Tuberculosis Infection Oth Test 0110 Tuberculosis Of Lung Infiltrative 01100 Tuberculosis Of Lung Infiltrative Uns Exam 01101 Tuberculosis Of Lung Infiltrative No Exam 01102 Tuberculosis Of Lung Infiltrative Exam Unkn 01103 Tuberculosis Of Lung Infiltrative Micro Dx 01104 Tuberculosis Of Lung Infiltrative Cult Dx 01105 Tuberculosis Of Lung Infiltrative Histo Dx 01106 Tuberculosis Of Lung Infiltrative Oth Test 01110 Tuberculosis Of Lung Nodular Uns Exam 01111 Tuberculosis Of Lung Nodular No Exam 01112 Tuberculosis Of Lung Nodular Exam Unkn 01113 Tuberculosis Of Lung Nodular Micro Dx 01114 Tuberculosis Of Lung Nodular Cult Dx 01115 Tuberculosis Of Lung Nodular Histo Dx 01116 Tuberculosis Of Lung Nodular Other Test 01120 Tuberculosis Of Lung W Cavitation Uns Exam 01121 Tuberculosis Of Lung W Cavitation No Exam 01122 Tuberculosis Of Lung W Cavitation Exam Unkn 01123 Tuberculosis Of Lung W Cavitation Micro Dx 01124 Tuberculosis Of Lung W Cavitation Cult Dx 01125 Tuberculosis Of Lung W Cavitation Histo Dx 01126 Tuberculosis Of Lung W Cavitation Oth Test 01130 Tuberculosis Of Bronchus Uns Exam 01131 Tuberculosis Of Bronchus No Exam 01132 Tuberculosis Of Bronchus Exam Unkn 01133 Tuberculosis Of Bronchus Micro Dx 01134 Tuberculosis Of Bronchus Cult Dx 01135 Tuberculosis Of Bronchus Histo Dx 01136 Tuberculosis Of Bronchus Other Test 01140 Tuberculosis Fibrosis Lung Uns Exam 01141 Tuberculosis Fibrosis Lung No Exam 01142 Tuberculosis Fibrosis Lung Exam Unkn 01143 Tuberculosis Fibrosis Lung Micro Dx 01144 Tuberculosis Fibrosis Lung Cult Dx 01145 Tuberculosis Fibrosis Lung Histo Dx 01146 Tuberculosis Fibrosis Lung Other Test 01150 Tuberculosis Bronchiectasis Uns Exam 01151 Tuberculosis Bronchiectasis No Exam 01152 Tuberculosis Bronchiectasis Exam Unkn 01153 Tuberculosis Bronchiectasis Micro Dx 01154 Tuberculosis Bronchiectasis Cult Dx 01155 Tuberculosis Bronchiectasis Histo Dx 01156 Tuberculosis Bronchiectasis Other Test 01160 Tuberculosis Pneumonia Uns Exam 01161 Tuberculosis Pneumonia No Exam 01162 Tuberculosis Pneumonia Exam Unkn 01163 Tuberculosis Pneumonia Micro Dx 01164 Tuberculosis Pneumonia Cult Dx

The Degge Group, Ltd. 12 aTNF Switching Study 04/06/2018 01165 Tuberculosis Pneumonia Histo Dx 01166 Tuberculosis Pneumonia Other Test 01170 Tuberculosis Pneumothorax Uns Exam 01171 Tuberculosis Pneumothorax No Exam 01172 Tuberculosis Pneumothorax Exam Unkn 01173 Tuberculosis Pneumothorax Micro Dx 01174 Tuberculosis Pneumothorax Cult Dx 01175 Tuberculosis Pneumothorax Histo Dx 01176 Tuberculosis Pneumothorax Other Test 01180 Other Pulmonary Tuberculosis Uns Exam 01181 Other Pulmonary Tuberculosis No Exam 01182 Other Pulmonary Tuberculosis Exam Unkn 01183 Other Pulmonary Tuberculosis Micro Dx 01184 Other Pulmonary Tuberculosis Cult Dx 01185 Other Pulmonary Tuberculosis Histo Dx 01186 Other Pulmonary Tuberculosis Other Test 01190 Uns Pulmonary Tuberculosis Uns Exam 01191 Uns Pulmonary Tuberculosis No Exam 01192 Uns Pulmonary Tuberculosis Exam Unkn 01193 Uns Pulmonary Tuberculosis Micro Dx 01194 Uns Pulmonary Tuberculosis Cult Dx 01195 Uns Pulmonary Tuberculosis Histo Dx 01196 Uns Pulmonary Tuberculosis Other Test 0120 Tuberculous Pleurisy 01200 Tuberculosis Pleurisy Uns Exam 01201 Tuberculosis Pleurisy No Exam 01202 Tuberculosis Pleurisy Exam Unkn 01203 Tuberculosis Pleurisy Micro Dx 01204 Tuberculosis Pleurisy Cult Dx 01205 Tuberculosis Pleurisy Histo Dx 01206 Tuberculosis Pleurisy Other Test 01210 Tuberculosis Of Intrathoracic Nodes Uns Exam 01211 Tuberculosis Of Intrathoracic Nodes No Exam 01212 Tuberculosis Of Intrathoracic Nodes Exam Unkn 01213 Tuberculosis Of Intrathoracic Nodes Micro Dx 01214 Tuberculosis Of Intrathoracic Nodes Cult Dx 01215 Tuberculosis Of Intrathoracic Nodes Histo Dx 01216 Tuberculosis Of Intrathoracic Nodes Oth Test 01220 Isolated Trach/Bronch Tuberculosis Uns Exam 01221 Isolated Trach/Bronch Tuberculosis No Exam 01222 Isolated Trach/Bronch Tuberculosis Exam Unkn 01223 Isolated Trach/Bronch Tuberculosis Micro Dx 01224 Isolated Trach/Bronch Tuberculosis Cult Dx 01225 Isolated Trach/Bronch Tuberculosis Histo Dx 01226 Isolated Trach/Bronch Tuberculosis Oth Test 01230 Tuberculosis Laryngitis Uns Exam 01231 Tuberculosis Laryngitis No Exam 01232 Tuberculosis Laryngitis Exam Unkn 01233 Tuberculosis Laryngitis Micro Dx 01234 Tuberculosis Laryngitis Cult Dx 01235 Tuberculosis Laryngitis Histo Dx 01236 Tuberculosis Laryngitis Other Test 01280 Other Respiratory Tuberculosis Uns Exam 01281 Other Respiratory Tuberculosis No Exam

The Degge Group, Ltd. 13 aTNF Switching Study 04/06/2018 01282 Other Respiratory Tuberculosis Exam Unkn 01283 Other Respiratory Tuberculosis Micro Dx 01284 Other Respiratory Tuberculosis Cult Dx 01285 Other Respiratory Tuberculosis Histo Dx 01286 Other Respiratory Tuberculosis Other Test 0130 Tuberculous Meningitis 01300 Tuberculosis Meningitis Uns Exam 01301 Tuberculosis Meningitis No Exam 01302 Tuberculosis Meningitis Exam Unkn 01303 Tuberculosis Meningitis Micro Dx 01304 Tuberculosis Meningitis Cult Dx 01305 Tuberculosis Meningitis Histo Dx 01306 Tuberculosis Meningitis Other Test 01310 Tuberculoma Of Meninges Uns Exam 01311 Tuberculoma Of Meninges No Exam 01312 Tuberculoma Of Meninges Exam Unkn 01313 Tuberculoma Of Meninges Micro Dx 01314 Tuberculoma Of Meninges Cult Dx 01315 Tuberculoma Of Meninges Histo Dx 01316 Tuberculoma Of Meninges Oth Test 01320 Tuberculoma Of Brain Uns Exam 01321 Tuberculoma Of Brain No Exam 01322 Tuberculoma Of Brain Exam Unkn 01323 Tuberculoma Of Brain Micro Dx 01324 Tuberculoma Of Brain Cult Dx 01325 Tuberculoma Of Brain Histo Dx 01326 Tuberculoma Of Brain Oth Test 01330 Tuberculosis Abscess Of Brain Uns Exam 01331 Tuberculosis Abscess Of Brain No Exam 01332 Tuberculosis Abscess Of Brain Exam Unkn 01333 Tuberculosis Abscess Of Brain Micro Dx 01334 Tuberculosis Abscess Of Brain Cult Dx 01335 Tuberculosis Abscess Of Brain Histo Dx 01336 Tuberculosis Abscess Of Brain Other Test 01340 Tuberculoma Of Spinal Cord Uns Exam 01341 Tuberculoma Of Spinal Cord No Exam 01342 Tuberculoma Of Spinal Cord Exam Unk 01343 Tuberculoma Of Spinal Cord Micro Dx 01344 Tuberculoma Of Spinal Cord Cult Dx 01345 Tuberculoma Of Spinal Cord Histo Dx 01346 Tuberculoma Of Spinal Cord Oth Test 01350 Tuberculosis Abscess Of Spinal Cord Uns Exam 01351 Tuberculosis Abscess Of Spinal Cord No Exam 01352 Tuberculosis Abscess Of Spinal Cord Exam Unkn 01353 Tuberculosis Abscess Of Spinal Cord Micro Dx 01354 Tuberculosis Abscess Of Spinal Cord Cult Dx 01355 Tuberculosis Abscess Of Spinal Cord Histo Dx 01356 Tuberculosis Abscess Of Spinal Cord Oth Test 01360 Tuberculosis Encephalitis/Myelitis Uns Exam 01361 Tuberculosis Encephalitis/Myelitis No Exam 01362 Tuberculosis Encephalitis/Myelitis Exam Unkn 01363 Tuberculosis Encephalitis/Myelitis Micro Dx 01364 Tuberculosis Encephalitis/Myelitis Cult Dx 01365 Tuberculosis Encephalitis/Myelitis Histo Dx

The Degge Group, Ltd. 14 aTNF Switching Study 04/06/2018 01366 Tuberculosis Encephalitis/Myelitis Oth Test 01380 Other Tuberculosis Cent Nerv Sys Uns Exam 01381 Other Tuberculosis Cent Nerv Sys No Exam 01382 Other Tuberculosis Cent Nerv Sys Exam Unkn 01383 Other Tuberculosis Cent Nerv Sys Micro Dx 01384 Other Tuberculosis Cent Nerv Sys Cult Dx 01385 Other Tuberculosis Cent Nerv Sys Histo Dx 01386 Other Tuberculosis Cent Nerv Sys Oth Test 01390 Uns Tuberculosis Cent Nerv Sys Uns Exam 01391 Uns Tuberculosis Cent Nerv Sys No Exam 01392 Uns Tuberculosis Cent Nerv Sys Exam Unkn 01393 Uns Tuberculosis Cent Nerv Sys Micro Dx 01394 Uns Tuberculosis Cent Nerv Sys Cult Dx 01395 Uns Tuberculosis Cent Nerv Sys Histo Dx 01396 Uns Tuberculosis Cent Nerv Sys Other Test 0140 Tuberculous Peritonitis 01400 Tuberculosis Peritonitis Uns Exam 01401 Tuberculosis Peritonitis No Exam 01402 Tuberculosis Peritonitis Exam Unkn 01403 Tuberculosis Peritonitis Micro Dx 01404 Tuberculosis Peritonitis Cult Dx 01405 Tuberculosis Peritonitis Histo Dx 01406 Tuberculosis Peritonitis Other Test 01480 Oth Tuberculosis Perit/Mesen Gland Uns Exam 01481 Oth Tuberculosis Perit/Mesen Glands No Exam 01482 Oth Tuberculosis Perit/Mesen Gland Exam Unkn 01483 Oth Tuberculosis Perit/Mesen Gland Micro Dx 01484 Oth Tuberculosis Perit/Mesen Gland Cult Dx 01485 Oth Tuberculosis Perit/Mesen Gland Histo Dx 01486 Oth Tuberculosis Perit/Mesen Gland Oth Test 0150 Tuberculosis Of Vertebral Column 01500 Tuberculosis Of Vertebral Column Uns Exam 01501 Tuberculosis Of Vertebral Column No Exam 01502 Tuberculosis Of Vertebral Column Exam Unkn 01503 Tuberculosis Of Vertebral Column Micro Dx 01504 Tuberculosis Of Vertebral Column Cult Dx 01505 Tuberculosis Of Vertebral Column Histo Dx 01506 Tuberculosis Of Vertebral Column Oth Test 01510 Tuberculosis Of Hip Uns Exam 01511 Tuberculosis Of Hip No Exam 01512 Tuberculosis Of Hip Exam Unkn 01513 Tuberculosis Of Hip Micro Dx 01514 Tuberculosis Of Hip Cult Dx 01515 Tuberculosis Of Hip Histo Dx 01516 Tuberculosis Of Hip Other Test 01520 Tuberculosis Of Knee Uns Exam 01521 Tuberculosis Of Knee No Exam 01522 Tuberculosis Of Knee Exam Unkn 01523 Tuberculosis Of Knee Micro Dx 01524 Tuberculosis Of Knee Cult Dx 01525 Tuberculosis Of Knee Histo Dx 01526 Tuberculosis Of Knee Other Test 01550 Tuberculosis Of Limb Bones Uns Exam 01551 Tuberculosis Of Limb Bones No Exam

The Degge Group, Ltd. 15 aTNF Switching Study 04/06/2018 01552 Tuberculosis Of Limb Bones Exam Unkn 01553 Tuberculosis Of Limb Bones Micro Dx 01554 Tuberculosis Of Limb Bones Cult Dx 01555 Tuberculosis Of Limb Bones Histo Dx 01556 Tuberculosis Of Limb Bones Other Test 01560 Tuberculosis Of Mastoid Uns Exam 01561 Tuberculosis Of Mastoid No Exam 01562 Tuberculosis Of Mastoid Exam Unkn 01563 Tuberculosis Of Mastoid Micro Dx 01564 Tuberculosis Of Mastoid Cult Dx 01565 Tuberculosis Of Mastoid Histo Dx 01566 Tuberculosis Of Mastoid Other Test 01570 Tuberculosis Of Other Bone Uns Exam 01571 Tuberculosis Of Other Bone No Exam 01572 Tuberculosis Of Other Bone Exam Unkn 01573 Tuberculosis Of Other Bone Micro Dx 01574 Tuberculosis Of Other Bone Cult Dx 01575 Tuberculosis Of Other Bone Histo Dx 01576 Tuberculosis Of Other Bone Oth Test 01580 Tuberculosis Of Other Joint Uns Exam 01581 Tuberculosis Of Other Joint No Exam 01582 Tuberculosis Of Other Joint Exam Unkn 01583 Tuberculosis Of Other Joint Micro Dx 01584 Tuberculosis Of Other Joint Cult Dx 01585 Tuberculosis Of Other Joint Histo Dx 01586 Tuberculosis Of Other Joint Oth Test 01590 Tuberculosis Of Uns Bones/Joints Uns Exam 01591 Tuberculosis Of Uns Bones/Joints No Exam 01592 Tuberculosis Of Uns Bones/Joints Exam Unkn 01593 Tuberculosis Of Uns Bones/Joints Micro Dx 01594 Tuberculosis Of Uns Bones/Joints Cult Dx 01595 Tuberculosis Of Uns Bones/Joints Histo Dx 01596 Tuberculosis Of Uns Bones/Joints Other Test 0160 Tuberculosis Of Kidney 01600 Tuberculosis Of Kidney Uns Exam 01601 Tuberculosis Of Kidney No Exam 01602 Tuberculosis Of Kidney Exam Unkn 01603 Tuberculosis Of Kidney Micro Dx 01604 Tuberculosis Of Kidney Cult Dx 01605 Tuberculosis Of Kidney Histo Dx 01606 Tuberculosis Of Kidney Other Test 01610 Tuberculosis Of Bladder Uns Exam 01611 Tuberculosis Of Bladder No Exam 01612 Tuberculosis Of Bladder Exam Unkn 01613 Tuberculosis Of Bladder Micro Dx 01614 Tuberculosis Of Bladder Cult Dx 01615 Tuberculosis Of Bladder Histo Dx 01616 Tuberculosis Of Bladder Other Test 01620 Tuberculosis Of Ureter Uns Exam 01621 Tuberculosis Of Ureter No Exam 01622 Tuberculosis Of Ureter Exam Unkn 01623 Tuberculosis Of Ureter Micro Dx 01624 Tuberculosis Of Ureter Cult Dx 01625 Tuberculosis Of Ureter Histo Dx

The Degge Group, Ltd. 16 aTNF Switching Study 04/06/2018 01626 Tuberculosis Of Ureter Other Test 01630 Tuberculosis Of Oth Urinary Organs Uns Exam 01631 Tuberculosis Of Oth Urinary Organs No Exam 01632 Tuberculosis Of Oth Urinary Organs Exam Unkn 01633 Tuberculosis Of Oth Urinary Organs Micro Dx 01634 Tuberculosis Of Oth Urinary Organs Cult Dx 01635 Tuberculosis Of Oth Urinary Organs Histo Dx 01636 Tuberculosis Of Oth Urinary Organs Oth Test 01640 Tuberculosis Of Epididymis Uns Exam 01641 Tuberculosis Of Epididymis No Exam 01642 Tuberculosis Of Epididymis Exam Unkn 01643 Tuberculosis Of Epididymis Micro Dx 01644 Tuberculosis Of Epididymis Cult Dx 01645 Tuberculosis Of Epididymis Histo Dx 01646 Tuberculosis Of Epididymis Other Test 01650 Tuberculosis Of Oth Male Gen Organs Uns Exam 01651 Tuberculosis Of Oth Male Gen Organs No Exam 01652 Tuberculosis Of Oth Male Gen Organs Exam Unkn 01653 Tuberculosis Of Oth Male Gen Organs Micro Dx 01654 Tuberculosis Of Oth Male Gen Organs Cult Dx 01655 Tuberculosis Of Oth Male Gen Organs Histo Dx 01656 Tuberculosis Of Oth Male Gen Organs Oth Test 01660 Tuberculosis Oophoritis/Salpingitis Uns Exam 01661 Tuberculosis Oophoritis/Salpingitis No Exam 01662 Tuberculosis Oophoritis/Salpingitis Exam Unkn 01663 Tuberculosis Oophoritis/Salpingitis Micro Dx 01664 Tuberculosis Oophoritis/Salpingitis Cult Dx 01665 Tuberculosis Oophoritis/Salpingitis Histo Dx 01666 Tuberculosis Oophoritis/Salpingitis Oth Test 01670 Tuberculosis Of Oth Fem Gen Organs Uns Exam 01671 Tuberculosis Of Oth Fem Gen Organs No Exam 01672 Tuberculosis Of Oth Fem Gen Organs Exam Unkn 01673 Tuberculosis Of Oth Fem Gen Organs Micro Dx 01674 Tuberculosis Of Oth Fem Gen Organs Cult Dx 01675 Tuberculosis Of Oth Fem Gen Organs Histo Dx 01676 Tuberculosis Of Oth Fem Gen Organs Oth Test 01690 Uns Genitourinary Tuberculosis Of Uns Exam 01691 Uns Genitourinary Tuberculosis Of No Exam 01692 Uns Genitourinary Tuberculosis Of Exam Unkn 01693 Uns Genitourinary Tuberculosis Of Micro Dx 01694 Uns Genitourinary Tuberculosis Of Cult Dx 01695 Uns Genitourinary Tuberculosis Of Histo Dx 01696 Uns Genitourinary Tuberculosis Of Oth Test 0170 Tuberculosis Skin And Subcutaneous Tissue 01700 Tuberculosis Of Skin/Subq Cellular Uns Exam 01701 Tuberculosis Of Skin Subq Cellular No Exam 01702 Tuberculosis Of Skin Subq Cellular Exam Unkn 01703 Tuberculosis Of Skin Subq Cellular Micro Dx 01704 Tuberculosis Of Skin Subq Cellular Cult Dx 01705 Tuberculosis Of Skin Subq Cellular Histo Dx 01706 Tuberculosis Of Skin Subq Cellular Oth Test 01710 Tuberculosis Erythema Nod W Hypsens Uns Exam 01711 Tuberculosis Erythema Nod W Hypsens No Exam 01712 Tuberculosis Erythema Nod W Hypsens Exam Unkn

The Degge Group, Ltd. 17 aTNF Switching Study 04/06/2018 01713 Tuberculosis Erythema Nod W Hypsens Micro Dx 01714 Tuberculosis Erythema Nod W Hypsens Cult Dx 01715 Tuberculosis Erythema Nod W Hypsens Histo Dx 01716 Tuberculosis Erythema Nod W Hypsens Oth Test 01720 Tuberculosis Peripheral Lymph Nodes Uns Exam 01721 Tuberculosis Peripheral Lymph Nodes No Exam 01722 Tuberculosis Peripheral Lymph Nodes Exam Unkn 01723 Tuberculosis Peripheral Lymph Nodes Micro Dx 01724 Tuberculosis Peripheral Lymph Nodes Cult Dx 01725 Tuberculosis Peripheral Lymph Nodes Histo Dx 01726 Tuberculosis Peripheral Lymph Nodes Oth Test 01730 Tuberculosis Of Eye Unspec 01731 Tuberculosis Of Eye No Exam 01732 Tuberculosis Of Eye Exam Unkn 01733 Tuberculosis Of Eye Micro Dx 01734 Tuberculosis Of Eye Cult Dx 01735 Tuberculosis Of Eye Histo Dx 01736 Tuberculosis Of Eye Ot Test 01740 Tuberculosis Of Ear Unspec 01741 Tuberculosis Of Ear No Exam 01742 Tuberculosis Of Ear Exam Unkn 01743 Tuberculosis Of Ear Micro Dx 01744 Tuberculosis Of Ear Cult Dx 01745 Tuberculosis Of Ear Histo Dx 01746 Tuberculosis Of Ear Ot Test 01750 Tuberculosis Of Thyroid Gland Uns Exam 01751 Tuberculosis Of Thyroid Gland No Exam 01752 Tuberculosis Of Thyroid Gland Exam Unkn 01753 Tuberculosis Of Thyroid Gland Micro Dx 01754 Tuberculosis Of Thyroid Gland Cult Dx 01755 Tuberculosis Of Thyroid Gland Histo Dx 01756 Tuberculosis Of Thyroid Gland Other Test 01760 Tuberculosis Of Adrenal Glands Uns Exam 01761 Tuberculosis Of Adrenal Glands No Exam 01762 Tuberculosis Of Adrenal Glands Exam Unkn 01763 Tuberculosis Of Adrenal Glands Micro Dx 01764 Tuberculosis Of Adrenal Glands Cult Dx 01765 Tuberculosis Of Adrenal Glands Histo Dx 01766 Tuberculosis Of Adrenal Glands Other Test 01770 Tuberculosis Of Spleen Uns Exam 01771 Tuberculosis Of Spleen No Exam 01772 Tuberculosis Of Spleen Exam Unkn 01773 Tuberculosis Of Spleen Micro Dx 01774 Tuberculosis Of Spleen Cult Dx 01775 Tuberculosis Of Spleen Histo Dx 01776 Tuberculosis Of Spleen Other Test 01780 Tuberculosis Of Esophagus Uns Exam 01781 Tuberculosis Of Esophagus No Exam 01782 Tuberculosis Of Esophagus Exam Unkn 01783 Tuberculosis Of Esophagus Micro Dx 01784 Tuberculosis Of Esophagus Cult Dx 01785 Tuberculosis Of Esophagus Histo Dx 01786 Tuberculosis Of Esophagus Other Test 01790 Tuberculosis Of Other Organs Uns Exam

The Degge Group, Ltd. 18 aTNF Switching Study 04/06/2018 01791 Tuberculosis Of Other Organs No Exam 01792 Tuberculosis Of Other Organs Exam Unkn 01793 Tuberculosis Of Other Organs Micro Dx 01794 Tuberculosis Of Other Organs Cult Dx 01795 Tuberculosis Of Other Organs Histo Dx 01796 Tuberculosis Of Other Organs Oth Test 0180 Acute Miliary Tuberculosis 01800 Acute Miliary Tuberculosis Uns Exam 01801 Acute Miliary Tuberculosis No Exam 01802 Acute Miliary Tuberculosis Exam Unkn 01803 Acute Miliary Tuberculosis Micro Dx 01804 Acute Miliary Tuberculosis Cult Dx 01805 Acute Miliary Tuberculosis Histo Dx 01806 Acute Miliary Tuberculosis Other Test 01880 Other Miliary Tuberculosis Uns Exam 01881 Other Miliary Tuberculosis No Exam 01882 Other Miliary Tuberculosis Exam Unkn 01883 Other Miliary Tuberculosis Micro Dx 01884 Other Miliary Tuberculosis Cult Dx 01885 Other Miliary Tuberculosis Histo Dx 01886 Other Miliary Tuberculosis Oth Test 01890 Uns Miliary Tuberculosis Uns Exam 01891 Uns Miliary Tuberculosis No Exam 01892 Uns Miliary Tuberculosis Exam Unkn 01893 Uns Miliary Tuberculosis Micro Dx 01894 Uns Miliary Tuberculosis Cult Dx 01895 Uns Miliary Tuberculosis Histo Dx 01896 Uns Miliary Tuberculosis Other Test 0310 Pulmonary Diseases Other Mycobact 0312 Disseminated Mycobacterium 039 Actinomycotic Infections 0390 Cutaneous Actinomycotic Infection 0391 Pulmonary Actinomycotic Infection 0392 Abdominal Actinomycotic Infection 0393 Cervicofacial Actinomycotic Infect 0394 Madura Foot Actinomycotic Infect 0398 Actinomycotic Infection Other Sites 0399 Actinomycotic Infection Uns Site 0461 Jakob Creutzfeldt Disease 0463 Prog Multifocal Leukoencephalopathy 053 Herpes Zoster 0530 Herpes Zoster W Meningitis 0531 Herpes Zoster W Nerv System Compli 05310 Herpes Zoster W Uns Nervous Compl 05311 Geniculate Herpes Zoster 05312 Postherpetic Trigeminal Neuralgia 05313 Postherpetic Polyneuropathy 05314 Herpes Zoster Myelitis 05319 Herpes Zoster W Oth Nervous Compli 0532 Herpes Zoster W Ophthalmic Complic 05320 Herpes Zoster Dermatitis Eyelid 05321 Herpes Zoster Keratoconjunctivitis 05322 Herpes Zoster Iridocyclitis 05329 Herpes Zoster W Oth Ophthalmic Comp

The Degge Group, Ltd. 19 aTNF Switching Study 04/06/2018 0537 Herpes Zoster W Other Complications 05371 Otitis External Herpes Zoster 05379 Herpes Zoster W Other Complications 0538 Herpes Zoster W Uns Complication 0539 Herpes Zoster Wo Complication 054 Herpes Simplex 0540 Eczema Herpeticum 0541 Genital Herpes 05410 Genital Herpes Unspec 05411 Herpetic Vulvovaginitis 05412 Herpetic Ulceration Vulva 05413 Herpetic Infection Penis 05419 Other Genital Herpes 0542 Herpetic Gingivostomatitis 0543 Herpetic Meningoencephalitis 0544 Herpes Simplex W Ophthalmic Complic 05440 Herpes Simp W Uns Ophthalmic Compl 05441 Herpes Simplex Dermatitis Eyelid 05442 Herpes Simplex Dendritic Keratitis 05443 Herpes Simplex Disciform Keratitis 05444 Herpes Simplex Iridocyclitis 05449 Herpes Simp W Oth Ophthalmic Compli 0545 Herpetic Septicemia 0546 Herpetic Whitlow 0547 Herpes Simplex W Other Complication 05471 Visceral Herpes Simplex 05472 Herpes Simplex Meningitis 05473 Herpes Simplex Otitis Externa 05474 Herpes Simplex Myelitis 05479 Herpes Simplex W Other Compli 0548 Herpes Simplex W Uns Compli 0549 Herpes Simplex Wo Compli 059 Other poxvirus infections 0588 Other human herpesvirus infection 0590 Other orthopoxvirus infections 0591 Other parapoxvirus infections 0592 Yatapoxvirus infections 0598 Other poxvirus infections 0599 Poxvirus infections, unspecified 07041 Acute Hepatitis C W Hepatic Coma 07044 Chr Hepatitis C W Coma 07051 Acute Hepatitis C Wo Hep Coma 07054 Chr Hepatitis C Wo Coma 07070 Uns Viral Hepatitis C Wo Coma 07071 Uns Viral Hepatitis C W Coma 0780 Molluscum Contagiosum 0781 Viral Warts 07810 Viral Warts Unspecified 07811 Condyloma Acuminatum 07819 Other Specified Viral Warts 0785 Cytomegaloviral Disease 0794 Human Papilloma Virus Infection 090 Congenital Syphilis 0900 Early Congenital Syphilis Sympt

The Degge Group, Ltd. 20 aTNF Switching Study 04/06/2018 0901 Early Congenital Syphilis Latent 0902 Uns Early Congenital Syphilis 0903 Syphilitic Interstitial Keratitis 0904 Juvenile Neurosyphilis 09040 Uns Juvenile Neurosyphilis 09041 Congenital Syphilitic Encephalitis 09042 Congenital Syphilitic Meningitis 09049 Oth Juvenile Neurosyphilis 0905 Oth Late Congenital Syphilis Sympt 0906 Late Congenital Syphilis Latent 0907 Uns Late Congenital Syphilis 0909 Congenital Syphilis Unspec 091 Early Syphilis Symptomatic 0910 Genital Syphilis 0911 Primary Anal Syphilis 0912 Other Primary Syphilis 0913 Secondary Syphilis Skin/Mucous Memb 0914 Adenopathy Secondary Syphilis 0915 Uveitis Due To Secondary Syphilis 09151 Syphilitic Chorioretinitis 09152 Syphilitic Iridocyclitis 0916 Secondary Syphilis Of Viscera/Bone 09161 Secondary Syphilitic Periostitis 09162 Secondary Syphilitic Hepatitis 09169 Secondary Syphilis Oth Viscera 0917 Secondary Syphilis Relapse 0918 Other Forms Of Secondary Syphilis 09181 Acute Syphilitic Meningitis 09182 Syphilitic Alopecia 09189 Oth Forms Secondary Syphilis 0919 Uns Secondary Syphilis 092 Early Syphilis Latent 0920 Early Syphilis Latent W Relapse 0929 Uns Early Syphilis Latent 093 Cardiovascular Syphilis 0930 Aneurysm Aorta Syphilitic 0931 Syphilitic Aortitis 0932 Syphilitic Endocarditis 09320 Uns Syphilitic Endocarditis Valve 09321 Syphilitic Mitral Valve 09322 Syphilitic Aortic Valve 09323 Syphilitic Tricuspid Valve 09324 Syphilitic Pulmonary Valve 0938 Other Cardiovascular Syphilis 09381 Syphilitic Pericarditis 09382 Syphilitic Myocarditis 09389 Other Cardiovascular Syphilis 0939 Uns Cardiovascular Syphilis 094 Neurosyphilis 0940 Tabes Dorsalis 0941 General Paresis 0942 Syphilitic Meningitis 0943 Asymptomatic Neurosyphilis 0948 Other Specified Neurosyphilis

The Degge Group, Ltd. 21 aTNF Switching Study 04/06/2018 09481 Syphilitic Encephalitis 09482 Syphilitic Parkinsonism 09483 Syphilitic Dissem Retinochoroiditis 09484 Syphilitic Optic Atrophy 09485 Syphilitic Retrobulbar Neuritis 09486 Syphilitic Acoustic Neuritis 09487 Syphilitic Rupt Cerebral Aneurysm 09489 Other Specified Neurosyphilis 0949 Neurosyphilis Unspecified 095 Other Late Syphilis With Symptoms 0950 Syphilitic Episcleritis 0951 Syphilis Lung 0952 Syphilitic Peritonitis 0953 Syphilis Liver 0954 Syphilis Kidney 0955 Syphilis Bone 0956 Syphilis Muscle 0957 Syphilis Synovium/Tendon/Bursa 0958 Other Forms Late Sympt Syphilis 0959 Uns Late Symptomatic Syphilis 096 Late Syphilis Latent 097 Other And Unspecified Syphilis 0970 Late Syphilis Unspecified 0971 Latent Syphilis Unspecified 0979 Syphilis Unspecified 1101 Dermatophytosis Nail 112 Candidiasis 1120 Candidiasis Mouth 1121 Candidiasis Vulva/Vagina 1122 Candidiasis Ot Urogenital Sites 1123 Candidiasis Skin/Nails 1124 Candidiasis Lung 1125 Disseminated Candidiasis 1128 Candidiasis Other Sites 11281 Candidal Endocarditis 11282 Candidal Otitis Externa 11283 Candidal Meningitis 11284 Candidal Esophagitis 11285 Candidal Enteritis 11289 Candidiasis Other Sites 1129 Candidiasis Uns Site 114 Coccidioidomycosis 1140 Primary Coccidioidomycosis 1141 Prim Extrapulm Coccidioidomycosis 1142 Coccidioidal Meningitis 1143 Ot Prog Coccidioidomycosis 1144 Chr Pulm Coccidioidomycosis 1145 Uns Pulm Coccidioidomycosis 1149 Coccidioidomycosis Unspec 115 Histoplasmosis 1150 Infection Histoplasma Capsulatum 11500 Histoplasma Capsulat Infec Wo Manif 11501 Histoplasma Capsulat Meningitis 11502 Histoplasma Capsulat Retinitis

The Degge Group, Ltd. 22 aTNF Switching Study 04/06/2018 11503 Histoplasma Capsulat Pericarditis 11504 Histoplasma Capsulat Endocarditis 11505 Histoplasma Capsulat Pneonia 11509 Histoplasma Capsulat W Oth Manif 1151 Infection By Histoplasma Duboisii 11510 Histoplasma Dub Infection Wo Manif 11511 Histoplasma Dub Meningitis 11512 Histoplasma Dub Retinitis 11513 Histoplasma Dub Pericarditis 11514 Histoplasma Dub Endocarditis 11515 Histoplasma Dub Pneumonia 11519 Histoplasma Dub Infect W Oth Manif 1159 Histoplasmosis Unspecified 11590 Uns Histoplasmosis Wo Manifestation 11591 Uns Histoplasmosis Meningitis 11592 Uns Histoplasmosis Retinitis 11593 Uns Histoplasmosis Pericarditis 11594 Uns Histoplasmosis Endocarditis 11595 Uns Histoplasmosis Pneumonia 11599 Uns Histoplasmosis W Oth Manif 116 Blastomycotic Infection 1160 Blastomycosis 1161 Paracoccidioidomycosis 1162 Lobomycosis 1173 Aspergillosis 1174 Mycotic Mycetomas 1175 Cryptococcosis 118 Opportunistic Mycoses 1288 Other specified helminthiasis 130 Toxoplasmosis 1300 Meningoencephalitis Toxoplasmosis 1301 Conjunctivitis Toxoplasmosis 1302 Chorioretinitis Toxoplasmosis 1303 Myocarditis Toxoplasmosis 1304 Pneumonitis Toxoplasmosis 1305 Hepatitis Toxoplasmosis 1307 Toxoplasmosis Other Sites 1308 Multisystemic Dissem Toxoplasmosis 1309 Toxoplasmosis Unspecified 1362 Free Living Amebae Infections 1363 Pneumocystosis 1368 Other Infectious/Parasitic Diseases 176 Kaposi's Sarcoma 1760 Kaposi's Sarcoma Skin 1761 Kaposi's Sarcoma Soft Tissue 1762 Kaposi's Sarcoma Palate 1763 Kaposi's Sarcoma Gastrointestinal 1764 Kaposi's Sarcoma Lung 1765 Kaposi's Sarcoma Lymph Nodes 1768 Kaposi's Sarcoma Other Sites 1769 Kaposi's Sarcoma Site Unspec 3210 Cryptococcal Meningitis 37005 Mycotic Corneal Ulcer 481 Pneumococcal Pneumonia

The Degge Group, Ltd. 23 aTNF Switching Study 04/06/2018 482 Other Bacterial Pneumonia 4820 Pneumonia Klebsiella Pneumoniae 4821 Pneumonia Pseudomonas 4822 Pneumonia Hemophilus Influenzae 4823 Pneumonia Due To Streptococcus 48230 Pneumonia Uns Streptococcus 48231 Pneumonia Streptococcus Group A 48232 Pneumonia Streptococcus Group B 48239 Pneumonia Oth Streptococcus 4824 Pneumonia Due To Staphylococcus 48240 Pneumonia Uns Staphylococcus 48241 Pneumonia Staphlococcus Aureus 48249 Oth Staphylococcus Pneumonia 4828 Pneumonia Due To Other Bacteria 48281 Pneumonia Anaerobes 48282 Pneumonia Escherichia Coli 48283 Pneumonia Oth Gram Negative Bact 48284 Legionnaires' Disease 48289 Pneumonia Other Bacteria 4829 Uns Bacterial Pneumonia 4830 Pneumonia Mycoplasma Pneumoniae 4846 Pneumonia Aspergillosis 4847 Pneumonia Oth Systemic Mycoses 5186 Allergic Bronchopulmonary Aspergill 5286 Leukoplakia Oral Mucosa

The Degge Group, Ltd. 24 aTNF Switching Study 04/06/2018 APPENDIX F. Procedural Codes Used to Define Joint Surgery

CPT- 4 Category description Procedures for hand/wrist 25040 Arthrotomy, radiocarpal or midcarpal joint, with exploration, drainage, or removal of foreign body 25085 Capsulotomy, wrist (eg, contracture) 25100 Arthrotomy, wrist joint; with biopsy 25101 Arthrotomy, wrist joint; with joint exploration, with or without biopsy, with or without removal of loose or foreign body 25105 Arthrotomy, wrist joint; with synovectomy 25118 Synovectomy, extensor tendon sheath, wrist, single compartment; 25119 Synovectomy, extensor tendon sheath, wrist, single compartment; with resection of distal ulna Capsulorrhaphy or reconstruction, wrist, open (eg, capsulodesis, ligament repair, tendon transfer or graft) (includes synovectomy, capsulotomy and open 25320 reduction) for carpal instability 25332 Arthroplasty, wrist, with or without interposition, with or without external or internal fixation 25394 Osteoplasty, carpal bone, shortening 25443 Arthroplasty with prosthetic replacement; scaphoid carpal (navicular) 25445 Arthroplasty with prosthetic replacement; trapezium 25446 Arthroplasty with prosthetic replacement; distal radius and partial or entire carpus (total wrist) 25447 Arthroplasty, interposition, intercarpal or carpometacarpal joints 25449 Revision of arthroplasty, including removal of implant, wrist joint 25670 Open treatment of radiocarpal or intercarpal dislocation, one or more bones 25800 Arthrodesis, wrist; complete, without bone graft (includes radiocarpal and/or intercarpal and/or carpometacarpal joints) 25805 Arthrodesis, wrist; with sliding graft 25810 Arthrodesis, wrist; with iliac or other autograft (includes obtaining graft) 25820 Arthrodesis, wrist; limited, without bone graft (eg, intercarpal or radiocarpal) 25825 Arthrodesis, wrist; with autograft (includes obtaining graft) 26070 Arthrotomy, with exploration, drainage, or removal of loose or foreign body; carpometacarpal joint 26075 Arthrotomy, with exploration, drainage, or removal of loose or foreign body; metacarpophalangeal joint, each 26080 Arthrotomy, with exploration, drainage, or removal of loose or foreign body; interphalangeal joint, each 26100 Arthrotomy with biopsy; carpometacarpal joint, each 26105 Arthrotomy with biopsy; metacarpophalangeal joint, each 26110 Arthrotomy with biopsy; interphalangeal joint, each 26130 Synovectomy, carpometacarpal joint

The Degge Group, Ltd. 25 aTNF Switching Study 04/06/2018 CPT- 4 Category description 26135 Synovectomy, metacarpophalangeal joint including intrinsic release and extensor hood reconstruction, each digit 26140 Synovectomy, proximal interphalangeal joint, including extensor reconstruction, each interphalangeal joint 26145 Synovectomy, tendon sheath, radical (tenosynovectomy), flexor tendon, palm and/or finger, each tendon 26160 Excision of lesion of tendon sheath or joint capsule (eg, cyst, mucous cyst, or ganglion), hand or finger 26170 Excision of tendon, palm, flexor or extensor, single, each tendon 26180 Excision of tendon, finger, flexor or extensor, each tendon 26340 Manipulation, finger joint, under anesthesia, each joint 26471 Tenodesis; of proximal interphalangeal joint, each joint 26474 Tenodesis; of distal joint, each joint 26476 Lengthening of tendon, extensor, hand or finger, each tendon 26477 Shortening of tendon, extensor, hand or finger, each tendon 26478 Lengthening of tendon, flexor, hand or finger, each tendon 26479 Shortening of tendon, flexor, hand or finger, each tendon 26480 Transfer or transplant of tendon, carpometacarpal area or dorsum of hand; without free graft, each tendon 26483 Transfer or transplant of tendon, carpometacarpal area or dorsum of hand; with free tendon graft (includes obtaining graft), each tendon 26525 Capsulectomy or capsulotomy; interphalangeal joint, each joint 26530 Arthroplasty, metacarpophalangeal joint; each joint 26531 Arthroplasty, metacarpophalangeal joint; with prosthetic implant, each joint 26540 Repair of collateral ligament, metacarpophalangeal or interphalangeal joint 26541 Reconstruction, collateral ligament, metacarpophalangeal joint, single; with tendon or fascial graft (includes obtaining graft) 26542 Reconstruction, collateral ligament, metacarpophalangeal joint, single; with local tissue (eg, adductor advancement) 26545 Reconstruction, collateral ligament, interphalangeal joint, single, including graft, each joint 26548 Repair and reconstruction, finger, volar plate, interphalangeal joint 26565 Osteotomy; metacarpal, each 26567 Osteotomy; phalanx of finger, each 26568 Osteoplasty, lengthening, metacarpal or phalanx 26841 Arthrodesis, carpometacarpal joint, thumb, with or without internal fixation; 26842 Arthrodesis, carpometacarpal joint, thumb, with or without internal fixation; with autograft (includes obtaining graft) 26843 Arthrodesis, carpometacarpal joint, digit, other than thumb, each; 26844 Arthrodesis, carpometacarpal joint, digit, other than thumb, each; with autograft (includes obtaining graft) 26850 Arthrodesis, metacarpophalangeal joint, with or without internal fixation; 26852 Arthrodesis, metacarpophalangeal joint, with or without internal fixation; with autograft (includes obtaining graft) 26860 Arthrodesis, interphalangeal joint, with or without internal fixation;

The Degge Group, Ltd. 26 aTNF Switching Study 04/06/2018 CPT- 4 Category description Arthrodesis, interphalangeal joint, with or without internal fixation; each additional interphalangeal joint (list separately in addition to code for primary 26861 procedure) 26862 Arthrodesis, interphalangeal joint, with or without internal fixation; with autograft (includes obtaining graft) Arthrodesis, interphalangeal joint, with or without internal fixation; with autograft (includes obtaining graft), each additional joint (list separately in addition 26863 to code for primary procedure) 28070 Synovectomy; intertarsal or tarsometatarsal joint, each 28072 Synovectomy; metatarsophalangeal joint, each 28272 Capsulotomy; interphalangeal joint, each joint (separate procedure) 28310 Osteotomy, shortening, angular or rotational correction; proximal phalanx, first toe (separate procedure) 28312 Osteotomy, shortening, angular or rotational correction; other phalanges, any toe 29840 Arthroscopy, wrist, diagnostic, with or without synovial biopsy (separate procedure) 29844 Arthroscopy, wrist, surgical; synovectomy, partial 29845 Arthroscopy, wrist, surgical; synovectomy, complete 29846 Arthroscopy, wrist, surgical; excision and/or repair of triangular fibrocartilage and/or joint debridement 29848 Endoscopy, wrist, surgical, with release of transverse carpal ligament 29900 Arthroscopy, metacarpophalangeal joint, diagnostic, includes synovial biopsy 29901 Arthroscopy, metacarpophalangeal joint, surgical; with debridement 29902 Arthroscopy, metacarpophalangeal joint, surgical; with reduction of displaced ulnar collateral ligament (eg, stenar lesion) Procedures for elbow/shoulder/arm area 23040 Arthrotomy, glenohumeral joint, including exploration, drainage, or removal of foreign body 23044 Arthrotomy, acromioclavicular, sternoclavicular joint, including exploration, drainage, or removal of foreign body 23101 Arthrotomy, acromioclavicular joint or sternoclavicular joint, including biopsy and/or excision of torn cartilage 23105 Arthrotomy; glenohumeral joint, with synovectomy, with or without biopsy 23106 Arthrotomy; sternoclavicular joint, with synovectomy, with or without biopsy 23405 Tenotomy, shoulder area; single tendon 23406 Tenotomy, shoulder area; multiple tendons through same incision 23420 Reconstruction of complete shoulder (rotator) cuff avulsion, chronic (includes acromioplasty) 23465 Capsulorrhaphy, glenohumeral joint, posterior, with or without bone block 23466 Capsulorrhaphy, glenohumeral joint, any type multi-directional instability 23470 Arthroplasty, glenohumeral joint; hemiarthroplasty 23472 Arthroplasty, glenohumeral joint; total shoulder (glenoid and proximal humeral replacement (eg, total shoulder)) 23480 Osteotomy, clavicle, with or without internal fixation; 23485 Osteotomy, clavicle, with or without internal fixation; with bone graft for nonunion or malunion (includes obtaining graft and/or necessary fixation) 23700 Manipulation under anesthesia, shoulder joint, including application of fixation apparatus (dislocation excluded)

The Degge Group, Ltd. 27 aTNF Switching Study 04/06/2018 CPT- 4 Category description 23800 Arthrodesis, glenohumeral joint; 23802 Arthrodesis, glenohumeral joint; with autogenous graft (includes obtaining graft) 24000 Arthrotomy, elbow, including exploration, drainage, or removal of foreign body 24100 Arthrotomy, elbow; with synovial biopsy only 24101 Arthrotomy, elbow; with joint exploration, with or without biopsy, with or without removal of loose or foreign body 24155 Resection of elbow joint (arthrectomy) 24160 Implant removal; elbow joint 24301 Muscle or tendon transfer, any type, upper arm or elbow, single (excluding 24320-24331) 24305 Tendon lengthening, upper arm or elbow, each tendon 24310 Tenotomy, open, elbow to shoulder, each tendon 24320 Tenoplasty, with muscle transfer, with or without free graft, elbow to shoulder, single (seddon-brookes type procedure) 24330 Flexor-plasty, elbow (eg, steindler type advancement); 24331 Flexor-plasty, elbow (eg, steindler type advancement); with extensor advancement 24341 Repair, tendon or muscle, upper arm or elbow, each tendon or muscle, primary or secondary (excludes rotator cuff) 24343 Repair lateral collateral ligament, elbow, with local tissue 24344 Reconstruction lateral collateral ligament, elbow, with tendon graft (includes harvesting of graft) 24345 Repair medial collateral ligament, elbow, with local tissue 24346 Reconstruction medial collateral ligament, elbow, with tendon graft (includes harvesting of graft) 24360 Arthroplasty, elbow; with membrane (eg, fascial) 24361 Arthroplasty, elbow; with distal humeral prosthetic replacement 24362 Arthroplasty, elbow; with implant and fascia lata ligament reconstruction 24363 Arthroplasty, elbow; with distal humerus and proximal ulnar prosthetic replacement (eg, total elbow) 24365 Arthroplasty, radial head; 24366 Arthroplasty, radial head; with implant 24800 Arthrodesis, elbow joint; local 24802 Arthrodesis, elbow joint; with autogenous graft (includes obtaining graft) 25107 Arthrotomy, distal radioulnar joint including repair of triangular cartilage, complex 25290 Tenotomy, open, flexor or extensor tendon, forearm and/or wrist, single, each tendon Reconstruction for stabilization of unstable distal ulna or distal radioulnar joint, secondary by soft tissue stabilization (eg, tendon transfer, tendon graft or 25337 weave, or tenodesis) with or without open reduction of distal radioulnar joint 25350 Osteotomy, radius; distal third 25390 Osteoplasty, radius or ulna; shortening 25391 Osteoplasty, radius or ulna; lengthening with autograft 25392 Osteoplasty, radius and ulna; shortening (excluding 64876)

The Degge Group, Ltd. 28 aTNF Switching Study 04/06/2018 CPT- 4 Category description 25393 Osteoplasty, radius and ulna; lengthening with autograft 25441 Arthroplasty with prosthetic replacement; distal radius 25442 Arthroplasty with prosthetic replacement; distal ulna 25443 Arthroplasty with prosthetic replacement; scaphoid carpal (navicular) 25444 Arthroplasty with prosthetic replacement; lunate 25830 Arthrodesis, distal radioulnar joint with segmental resection of ulna, with or without bone graft (eg, sauve-kapandji procedure) 26060 Tenotomy, percutaneous, single, each digit 26450 Tenotomy, flexor, palm, open, each tendon 26455 Tenotomy, flexor, finger, open, each tendon 26460 Tenotomy, extensor, hand or finger, open, each tendon 27003 Tenotomy, adductor, subcutaneous, open, with obturator neurectomy 27054 Arthrotomy with synovectomy, hip joint 29805 Arthroscopy, shoulder, diagnostic, with or without synovial biopsy (separate procedure) 29806 Arthroscopy, shoulder, surgical; capsulorrhaphy 29807 Arthroscopy, shoulder, surgical; repair of slap lesion 29819 Arthroscopy, shoulder, surgical; with removal of loose body or foreign body 29820 Arthroscopy, shoulder, surgical; synovectomy, partial 29821 Arthroscopy, shoulder, surgical; synovectomy, complete 29822 Arthroscopy, shoulder, surgical; debridement, limited 29823 Arthroscopy, shoulder, surgical; debridement, extensive 29824 Arthroscopy, shoulder, surgical; distal claviculectomy including distal articular surface (mumford procedure) 29825 Arthroscopy, shoulder, surgical; with lysis and resection of adhesions, with or without manipulation 29826 Arthroscopy, shoulder, surgical; decompression of subacromial space with partial acromioplasty, with or without coracoacromial release 29827 Arthroscopy, shoulder, surgical; with rotator cuff repair 29830 Arthroscopy, elbow, diagnostic, with or without synovial biopsy (separate procedure) 29834 Arthroscopy, elbow, surgical; with removal of loose body or foreign body 29835 Arthroscopy, elbow, surgical; synovectomy, partial 29836 Arthroscopy, elbow, surgical; synovectomy, complete 29837 Arthroscopy, elbow, surgical; debridement, limited 29838 Arthroscopy, elbow, surgical; debridement, extensive Procedures for hip area 24301 Muscle or tendon transfer, any type, upper arm or elbow, single (excluding 24320-24331) 24400 Osteotomy, humerus, with or without internal fixation

The Degge Group, Ltd. 29 aTNF Switching Study 04/06/2018 CPT- 4 Category description 24420 Osteoplasty, humerus (eg, shortening or lengthening) (excluding 64876) 27000 Tenotomy, adductor of hip, percutaneous (separate procedure) 27001 Tenotomy, adductor of hip, open 27005 Tenotomy, hip flexor(s), open (separate procedure) 27006 Tenotomy, abductors and/or extensor(s) of hip, open (separate procedure) 27033 Arthrotomy, hip, including exploration or removal of loose or foreign body Capsulectomy or capsulotomy, hip, with or without excision of heterotopic bone, with release of hip flexor muscles (ie, gluteus medius, gluteus minimus, 27036 tensor fascia latae, rectus femoris, sartorius, iliopsoas) 27050 Arthrotomy, with biopsy; sacroiliac joint 27052 Arthrotomy, with biopsy; hip joint 27125 Hemiarthroplasty, hip, partial (eg, femoral stem prosthesis, bipolar arthroplasty) 27130 Arthroplasty, acetabular and proximal femoral prosthetic replacement (total hip arthroplasty), with or without autograft or allograft 27132 Conversion of previous hip surgery to total hip arthroplasty, with or without autograft or allograft 27134 Revision of total hip arthroplasty; both components, with or without autograft or allograft 27137 Revision of total hip arthroplasty; acetabular component only, with or without autograft or allograft 27138 Revision of total hip arthroplasty; femoral component only, with or without allograft 27140 Osteotomy and transfer of greater trochanter of femur (separate procedure) 27146 Osteotomy, iliac, acetabular or innominate bone; 27147 Osteotomy, iliac, acetabular or innominate bone; with open reduction of hip 27151 Osteotomy, iliac, acetabular or innominate bone; with femoral osteotomy 27156 Osteotomy, iliac, acetabular or innominate bone; with femoral osteotomy and with open reduction of hip 27161 Osteotomy, femoral neck (separate procedure) 27275 Manipulation, hip joint, requiring general anesthesia 27284 Arthrodesis, hip joint (including obtaining graft); 27286 Arthrodesis, hip joint (including obtaining graft); with subtrochanteric osteotomy 27448 Osteotomy, femur, shaft or supracondylar; without fixation 27450 Osteotomy, femur, shaft or supracondylar; with fixation 27465 Osteoplasty, femur; shortening (excluding 64876) 27466 Osteoplasty, femur; lengthening 27468 Osteoplasty, femur; combined, lengthening and shortening with femoral segment transfer 29860 Arthroscopy, hip, diagnostic with or without synovial biopsy (separate procedure) 29861 Arthroscopy, hip, surgical; with removal of loose body or foreign body 29862 Arthroscopy, hip, surgical; with debridement/shaving of articular cartilage (chondroplasty), abrasion arthroplasty, and/or resection of labrum

The Degge Group, Ltd. 30 aTNF Switching Study 04/06/2018 CPT- 4 Category description 29863 Arthroscopy, hip, surgical; with synovectomy Procedures for knee area 27330 Arthrotomy, knee; with synovial biopsy only 27331 Arthrotomy, knee; including joint exploration, biopsy, or removal of loose or foreign bodies 27332 Arthrotomy, with excision of semilunar cartilage (meniscectomy) knee; medial or lateral 27333 Arthrotomy, with excision of semilunar cartilage (meniscectomy) knee; medial and lateral 27334 Arthrotomy, with synovectomy, knee; anterior or posterior 27335 Arthrotomy, with synovectomy, knee; anterior and posterior including popliteal area 27390 Tenotomy, open, hamstring, knee to hip; single tendon 27391 Tenotomy, open, hamstring, knee to hip; multiple tendons, one leg 27392 Tenotomy, open, hamstring, knee to hip; multiple tendons, bilateral 27403 Arthrotomy with meniscus repair, knee 27427 Ligamentous reconstruction (augmentation), knee; extra-articular 27428 Ligamentous reconstruction (augmentation), knee; intra-articular (open) 27429 Ligamentous reconstruction (augmentation), knee; intra-articular (open) and extra-articular 27435 Capsulotomy, posterior capsular release, knee 27437 Arthroplasty, patella; without prosthesis 27438 Arthroplasty, patella; with prosthesis 27440 Arthroplasty, knee, tibial plateau; 27441 Arthroplasty, knee, tibial plateau; with debridement and partial synovectomy 27442 Arthroplasty, femoral condyles or tibial plateau(s), knee; 27443 Arthroplasty, femoral condyles or tibial plateau(s), knee; with debridement and partial synovectomy 27445 Arthroplasty, knee, hinge prosthesis (eg, walldius type) 27446 Arthroplasty, knee, condyle and plateau; medial or lateral compartment 27447 Arthroplasty, knee, condyle and plateau; medial and lateral compartments with or without patella resurfacing (total knee arthroplasty) 27486 Revision of total knee arthroplasty, with or without allograft; one component 27487 Revision of total knee arthroplasty, with or without allograft; femoral and entire tibial component 27570 Manipulation of knee joint under general anesthesia (includes application of traction or other fixation devices) 27580 Arthrodesis, knee, any technique 27712 Osteotomy; multiple, with realignment on intramedullary rod (eg, sofield type procedure) 27715 Osteoplasty, tibia and fibula, lengthening or shortening 27871 Arthrodesis, tibiofibular joint, proximal or distal 29866 Arthroscopy, knee, surgical; osteochondral autograft(s) (eg, mosaicplasty) (includes harvesting of the autograft)

The Degge Group, Ltd. 31 aTNF Switching Study 04/06/2018 CPT- 4 Category description 29867 Arthroscopy, knee, surgical; osteochondral allograft (eg, mosaicplasty) 29868 Arthroscopy, knee, surgical; meniscal transplantation (includes arthrotomy for meniscal insertion), medial or lateral 29870 Arthroscopy, knee, diagnostic, with or without synovial biopsy (separate procedure) 29873 Arthroscopy, knee, surgical; with lateral release 29874 Arthroscopy, knee, surgical; for removal of loose body or foreign body (eg, osteochondritis dissecans fragmentation, chondral fragmentation) 29875 Arthroscopy, knee, surgical; synovectomy, limited (eg, plica or shelf resection) (separate procedure) 29876 Arthroscopy, knee, surgical; synovectomy, major, two or more compartments (eg, medial or lateral) 29877 Arthroscopy, knee, surgical; debridement/shaving of articular cartilage (chondroplasty) 29879 Arthroscopy, knee, surgical; abrasion arthroplasty (includes chondroplasty where necessary) or multiple drilling or microfracture 29880 Arthroscopy, knee, surgical; with meniscectomy (medial and lateral, including any meniscal shaving) 29881 Arthroscopy, knee, surgical; with meniscectomy (medial or lateral, including any meniscal shaving) 29882 Arthroscopy, knee, surgical; with meniscus repair (medial or lateral) 29883 Arthroscopy, knee, surgical; with meniscus repair (medial and lateral) 29884 Arthroscopy, knee, surgical; with lysis of adhesions, with or without manipulation (separate procedure) Arthroscopy, knee, surgical; drilling for osteochondritis dissecans with bone grafting, with or without internal fixation (including debridement of base of 29885 lesion) 29886 Arthroscopy, knee, surgical; drilling for intact osteochondritis dissecans lesion 29887 Arthroscopy, knee, surgical; drilling for intact osteochondritis dissecans lesion with internal fixation Procedures for ankle/foot joints 26535 Arthroplasty, interphalangeal joint; each joint 26536 Arthroplasty, interphalangeal joint; with prosthetic implant, each joint 27605 Tenotomy, percutaneous, achilles tendon (separate procedure); local anesthesia 27606 Tenotomy, percutaneous, achilles tendon (separate procedure); general anesthesia 27610 Arthrotomy, ankle, including exploration, drainage, or removal of foreign body 27612 Arthrotomy, posterior capsular release, ankle, with or without achilles tendon lengthening 27620 Arthrotomy, ankle, with joint exploration, with or without biopsy, with or without removal of loose or foreign body 27625 Arthrotomy, with synovectomy, ankle; 27626 Arthrotomy, with synovectomy, ankle; including tenosynovectomy 27700 Arthroplasty, ankle; 27702 Arthroplasty, ankle; with implant (total ankle) 27703 Arthroplasty, ankle; revision, total ankle 27870 Arthrodesis, ankle, open 28010 Tenotomy, percutaneous, toe; single tendon 28011 Tenotomy, percutaneous, toe; multiple tendons

The Degge Group, Ltd. 32 aTNF Switching Study 04/06/2018 CPT- 4 Category description 28020 Arthrotomy, including exploration, drainage, or removal of loose or foreign body; intertarsal or tarsometatarsal jt 28022 Arthrotomy, including exploration, drainage, or removal of loose or foreign body; metatarsophalangeal joint 28024 Arthrotomy, including exploration, drainage, or removal of loose or foreign body; interphalangeal joint 28050 Arthrotomy with biopsy; intertarsal or tarsometatarsal joint 28052 Arthrotomy with biopsy; metatarsophalangeal joint 28054 Arthrotomy with biopsy; interphalangeal joint 28070 Synovectomy; intertarsal or tarsometatarsal joint, each 28086 Synovectomy, tendon sheath, foot; flexor 28088 Synovectomy, tendon sheath, foot; extensor 28090 Excision of lesion, tendon, tendon sheath, or capsule (including synovectomy) (eg, cyst or ganglion); foot 28092 Excision of lesion, tendon, tendon sheath, or capsule (including synovectomy) (eg, cyst or ganglion); toe(s), each 28230 Tenotomy, open, tendon flexor; foot, single or multiple tendon(s) (separate procedure) 28232 Tenotomy, open, tendon flexor; toe, single tendon (separate procedure) 28234 Tenotomy, open, extensor, foot or toe, each tendon 28260 Capsulotomy, midfoot; medial release only (separate procedure) 28261 Capsulotomy, midfoot; with tendon lengthening 28262 Capsulotomy, midfoot; extensive, including posterior talotibial capsulotomy and tendon(s) lengthening (eg, resistant clubfoot deformity) 28264 Capsulotomy, midtarsal (eg, heyman type procedure) 28270 Capsulotomy; metatarsophalangeal joint, with or without tenorrhaphy, each joint (separate procedure) 28302 Osteotomy; talus 28304 Osteotomy, tarsal bones, other than calcaneus or talus; 28305 Osteotomy, tarsal bones, other than calcaneus or talus; with autograft (includes obtaining graft) (eg, fowler type) 28306 Osteotomy, with or without lengthening, shortening or angular correction, metatarsal; first metatarsal 28307 Osteotomy, with or without lengthening, shortening or angular correction, metatarsal; first metatarsal with autograft (other than first toe) 28308 Osteotomy, with or without lengthening, shortening or angular correction, metatarsal; other than first metatarsal, each 28309 Osteotomy, with or without lengthening, shortening or angular correction, metatarsal; multiple (eg, swanson type cavus foot procedure) 28313 Reconstruction, angular deformity of toe, soft tissue procedures only (eg, overlapping second toe, fifth toe, curly toes) 28705 Arthrodesis; pantalar 28715 Arthrodesis; triple 28725 Arthrodesis; subtalar 28730 Arthrodesis, midtarsal or tarsometatarsal, multiple or transverse; 28735 Arthrodesis, midtarsal or tarsometatarsal, multiple or transverse; with osteotomy (eg, flatfoot correction) 28737 Arthrodesis, with tendon lengthening and advancement, midtarsal, tarsal navicular-cuneiform (eg, miller type procedure)

The Degge Group, Ltd. 33 aTNF Switching Study 04/06/2018 CPT- 4 Category description 28740 Arthrodesis, midtarsal or tarsometatarsal, single joint 28755 Arthrodesis, great toe; interphalangeal joint 28760 Arthrodesis, with extensor hallucis longus transfer to first metatarsal neck, great toe, interphalangeal joint (eg, jones type procedure) 29891 Arthroscopy, ankle, surgical, excision of osteochondral defect of talus and/or tibia, including drilling of the defect 29894 Arthroscopy, ankle (tibiotalar and fibulotalar joints), surgical; with removal of loose body or foreign body 29895 Arthroscopy, ankle (tibiotalar and fibulotalar joints), surgical; synovectomy, partial 29897 Arthroscopy, ankle (tibiotalar and fibulotalar joints), surgical; debridement, limited 29898 Arthroscopy, ankle (tibiotalar and fibulotalar joints), surgical; debridement, extensive 29899 Arthroscopy, ankle (tibiotalar and fibulotalar joints), surgical; with ankle arthrodesis Procedures for lumbar/spine/jaw/other 21010 Arthrotomy, temporomandibular joint 21240 Arthroplasty, temporomandibular joint, with or without autograft (includes obtaining graft) 21242 Arthroplasty, temporomandibular joint, with allograft 21243 Arthroplasty, temporomandibular joint, with prosthetic joint replacement 22210 Osteotomy of spine, posterior or posterolateral approach, one vertebral segment; cervical 22212 Osteotomy of spine, posterior or posterolateral approach, one vertebral segment; thoracic 22214 Osteotomy of spine, posterior or posterolateral approach, one vertebral segment; lumbar Osteotomy of spine, posterior or posterolateral approach, one vertebral segment; each additional vertebral segment (list separately in addition to primary 22216 procedure) 22220 Osteotomy of spine, including discectomy, anterior approach, single vertebral segment; cervical 22222 Osteotomy of spine, including discectomy, anterior approach, single vertebral segment; thoracic 22224 Osteotomy of spine, including discectomy, anterior approach, single vertebral segment; lumbar Osteotomy of spine, including discectomy, anterior approach, single vertebral segment; each additional vertebral segment (list separately in addition to 22226 code for primary procedure) 22532 Arthrodesis, lateral extracavitary technique, including minimal discectomy to prepare interspace (other than for decompression); thoracic 22533 Arthrodesis, lateral extracavitary technique, including minimal discectomy to prepare interspace (other than for decompression); lumbar Arthrodesis, lateral extracavitary technique, including minimal discectomy to prepare interspace (other than for decompression); thoracic or lumbar, each 22534 additional vertebral segment (list separately in addition to code for primary procedure) 22548 Arthrodesis, anterior transoral or extraoral technique, clivus-c1-c2 (atlas-axis), with or without excision of odontoid process 22554 Arthrodesis, anterior interbody technique, including minimal discectomy to prepare interspace (other than for decompression); cervical below c2 22556 Arthrodesis, anterior interbody technique, including minimal discectomy to prepare interspace (other than for decompression); thoracic 22558 Arthrodesis, anterior interbody technique, including minimal discectomy to prepare interspace (other than for decompression); lumbar Arthrodesis, anterior interbody technique, including minimal discectomy to prepare interspace (other than for decompression); each additional interspace 22585 (list separately in addition to code for primary procedure) 22590 Arthrodesis, posterior technique, craniocervical (occiput-c2)

The Degge Group, Ltd. 34 aTNF Switching Study 04/06/2018 CPT- 4 Category description 22595 Arthrodesis, posterior technique, atlas-axis (c1-c2) 22600 Arthrodesis, posterior or posterolateral technique, single level; cervical below c2 segment 22610 Arthrodesis, posterior or posterolateral technique, single level; thoracic (with or without lateral transverse technique) 22612 Arthrodesis, posterior or posterolateral technique, single level; lumbar (with or without lateral transverse technique) Arthrodesis, posterior or posterolateral technique, single level; each additional vertebral segment (list separately in addition to code for primary 22614 procedure) Arthrodesis, posterior interbody technique, including laminectomy and/or discectomy to prepare interspace (other than for decompression), single 22630 interspace; lumbar Arthrodesis, posterior interbody technique, including laminectomy and/or discectomy to prepare interspace (other than for decompression), single 22632 interspace; each additional interspace (list separately in addition to code for primary procedure) 22800 Arthrodesis, posterior, for spinal deformity, with or without cast; up to 6 vertebral segments 22802 Arthrodesis, posterior, for spinal deformity, with or without cast; 7 to 12 vertebral segments 22804 Arthrodesis, posterior, for spinal deformity, with or without cast; 13 or more vertebral segments Total disc arthroplasty (artificial disc), anterior approach, including discectomy to prepare interspace (other than for decompression), lumbar, single 22857 interspace 22862 Revision including replacement of total disc arthroplasty (artificial disc) anterior approach, lumbar, single interspace 22865 Removal of total disc arthroplasty (artificial disc), anterior approach, lumbar, single interspace 23450 Capsulorrhaphy, anterior; putti-platt procedure or magnuson type operation 23455 Capsulorrhaphy, anterior; with labral repair (eg, bankart procedure) 26500 Reconstruction of tendon pulley, each tendon; with local tissues (separate procedure) 27280 Arthrodesis, sacroiliac joint (including obtaining graft) 27282 Arthrodesis, symphysis pubis (including obtaining graft) 29800 Arthroscopy, temporomandibular joint, diagnostic, with or without synovial biopsy (separate procedure) 29804 Arthroscopy, temporomandibular joint, surgical Total disc arthroplasty (artificial disc), anterior approach, including discectomy to prepare interspace (other than for decompression) cervical; single 0090T interspace Total disc arthroplasty (artificial disc), anterior approach, including discectomy to prepare interspace (other than for decompression) cervical; each 0092T additional interspace (list separately in addition to code for primary procedure) 0093T Removal of total disc arthroplasty, anterior approach cervical; single interspace 0095T Removal of total disc arthroplasty, anterior approach cervical; each additional interspace (list separately in addition to code for primary procedure) 0096T Revision of total disc arthroplasty, anterior approach cervical; single interspace 0098T Revision of total disc arthroplasty, anterior approach cervical; each additional interspace (list separately in addition to code for primary procedure) Total disc arthroplasty (artificial disc), anterior approach, including discectomy to prepare interspace (other than for decompression), lumbar, each 0163T additional interspace 0164T Removal of total disc arthroplasty, anterior approach, lumbar, each additional interspace 0165T Revision of total disc arthroplasty, anterior approach, lumbar, each additional interspace

The Degge Group, Ltd. 35 aTNF Switching Study 04/06/2018 ICD-9 Category description Incision and excision of joint structures Arthrotomy for removal of prosthesis (Includes removal of posterior spinal motion preservation (dynamic stabilization, facet replacement, interspinous 80.0* process) device(s)) 80.1* Other arthrotomy 80.2* Arthroscopy 80.3* Biopsy of joint structure 80.4* Division of joint capsule, ligament, or cartilage 80.5* Excision, destruction and other repair of intervertebral disc 80.6* Excision of semilunar cartilage of knee 80.7* Synovectomy 80.8* Other local excision or destruction of lesion of joint 80.9* Other excision of joint Repair and plastic operations on joint structures 81.1 Arthrodesis and arthroereisis of foot and ankle (Includes: arthrodesis of foot and ankle with: bone graft, external fixation device) 81.11 Ankle fusion, Tibiotalar fusion 81.12 Triple arthrodesis,Talus to calcaneus and calcaneus to cuboid and navicular 81.13 Subtalar fusion 81.14 Midtarsal fusion 81.15 Tarsometatarsal fusion 81.16 Metatarsophalangeal fusion 81.17 Other fusion of foot 81.18 Subtalar joint arthroereisis 81.2 Arthrodesis of other joint (Includes: arthrodesis with: bone graft external fixation device excision of bone ends and compression) 81.20 Arthrodesis of unspecified joint 81.21 Arthrodesis of hip 81.22 Arthrodesis of knee 81.23 Arthrodesis of shoulder 81.24 Arthrodesis of elbow 81.25 Carporadial fusion 81.26 Metacarpocarpal fusion 81.27 Metacarpophalangeal fusion 81.28 Interphalangeal fusion 81.29 Arthrodesis of other specified joints

The Degge Group, Ltd. 36 aTNF Switching Study 04/06/2018 ICD-9 Category description 81.3 Refusion of spine (Includes: arthrodesis of spine with: bone graft internal fixation correction of pseudarthrosis of spine) 81.30 Refusion of spine, not otherwise specified Refusion of atlas-axis spine, Craniocervical fusion by anterior, transoral, or posterior technique, C1-C2 fusion by anterior, transoral, or posterior 81.31 technique, Occiput C2 fusion by anterior, transoral, or posterior technique 81.32 Refusion of other cervical spine, anterior technique (Arthrodesis of C2 level or below) 81.33 Refusion of other cervical spine, posterior technique (Arthrodesis of C2 level or below) 81.34 Refusion of dorsal and dorsolumbar spine, anterior technique (Arthrodesis of thoracic or thoracolumbar region) 81.35 Refusion of dorsal and dorsolumbar spine, posterior technique (Arthrodesis of thoracic or thoracolumbar region) 81.36 Refusion of lumbar and lumbosacral spine, anterior technique (Anterior lumbar interbody fusion (ALIF); Arthrodesis of lumbar or lumbosacral region) 81.37 Refusion of lumbar and lumbosacral spine, lateral transverse process technique Refusion of lumbar and lumbosacral spine, posterior technique, Arthrodesis of lumbar or lumbosacral region 81.38 81.39 Refusion of spine, not elsewhere classified Other repair of joint of lower extremity (Includes: arthroplasty of lower extremity with: external traction or fixation, graft of bone (chips) or 81.4 cartilage internal fixation device) 81.40 Repair of hip, not elsewhere classified Five-in-one repair of knee, Medial meniscectomy, medial collateral ligament repair, vastus medialis advancement, semitendinosus advancement, and pes 81.42 anserinus transfer 81.43 Triad knee repair, Medial meniscectomy with repair of the anterior cruciate ligament and the medial collateral ligament (O'Donoghue procedure) 81.44 Patellar stabilization (Roux-Goldthwait operation for recurrent dislocation of patella) 81.45 Other repair of the cruciate ligaments 81.46 Other repair of the collateral ligaments 81.47 Other repair of knee 81.49 Other repair of ankle Joint replacement of lower extremity (Includes: arthroplasty of lower extremity with: external traction or fixation graft of bone (chips) or 81.5 cartilage internal fixation device or prosthesis) 81.51 Total hip replacement, Replacement of both femoral head and acetabulum by prosthesis, Total reconstruction of hip 81.52 Partial hip replacement, Bipolar endoprosthesis 81.53 Revision of hip replacement, not otherwise specified, Revision of hip replacement, not specified as to components(s) replaced, (acetabular, femoral, both) 81.54 Total knee replacement (Bicompartmental, Tricompartmental, Unicompartmental (hemijoint)) 81.55 Revision of knee replacement,not otherwise specified 81.56 Total ankle replacement 81.57 Replacement of joint of foot and toe 81.59 Revision of joint replacement of lower extremity, not elsewhere classified 81.6 Other procedures on spine

The Degge Group, Ltd. 37 aTNF Switching Study 04/06/2018 ICD-9 Category description 81.62 Fusion or refusion of 2-3 vertebrae 81.63 Fusion or refusion of 4- 8 vertebrae 81.64 Fusion or refusion of 9 or more vertebrae 81.65 Percutaneous vertebroplasty, Injection of bone void filler (cement) (polymethylmethacrylate) (PMMA) into the diseased or fractured, vertebral body Percutaneous vertebral augmentation, Insertion of inflatable balloon, bone tamp, or other device displacing (removing) (compacting) bone to create a 81.66 space (cavity) (void) prior to the injection of bone void filler (cement) (polymethylmethacrylate) (PMMA) or other substance, Arcuplasty, Kyphoplasty, SKyphoplasty, Spineoplasty Arthroplasty and repair of hand, fingers and wrist (Includes: arthroplasty of hand and finger with: external traction or fixation, graft of bone 81.7 (chips) or cartilage, internal fixation device or prosthesis) 81.71 Arthroplasty of metacarpophalangeal and interphalangeal joint with implant 81.72 Arthroplasty of metacarpophalangeal and interphalangeal joint without implant 81.73 Total wrist replacement 81.74 Arthroplasty of carpocarpal or carpometacarpal joint with implant 81.75 Arthroplasty of carpocarpal or carpometacarpal joint without implant 81.79 Other repair of hand, fingers and wrist Arthroplasty and repair of shoulder and elbow (Includes: arthroplasty of upper limb NEC with: external traction or fixation graft of bone (chips) 81.8 or cartilage internal fixation device or prosthesis 81.80 Total shoulder replacement 81.81 Partial shoulder replacement 81.82 Repair of recurrent dislocation of shoulder 81.83 Other repair of shoulder, Revision of arthroplasty of shoulder 81.84 Total elbow replacement 81.85 Other repair of elbow 81.9 Other operations on joint structures 81.91 Arthrocentesis, Joint aspiration 81.92 Injection of therapeutic substance into joint or ligament 81.93 Suture of capsule or ligament of upper extremity 81.94 Suture of capsule or ligament of ankle and foot 81.94 Suture of capsule or ligament of ankle and foot 81.95 Suture of capsule or ligament of other lower extremity 81.96 Other repair of joint 81.97 Revision of joint replacement of upper extremity (Partial, Removal of cement spacer, Total) 81.98 Other diagnostic procedures on joint structures 81.99 Other

The Degge Group, Ltd. 38 aTNF Switching Study 04/06/2018 * The following fourth-digit subclassification is for use with ICD-9-CM procedure code range 80.0-80.9: 0 unspecified site 1 shoulder 2 elbow 3 wrist 4 hand and finger 5 hip 6 knee 7 ankle 8 foot and toe 9 other specified sites

The Degge Group, Ltd. 39 aTNF Switching Study 04/06/2018 APPENDIX G. Medications Used to Define DMARD Treatment*

Generic Brand Names Auranofin Ridaura Aurothioglucose Solganal Azathioprine Azathioprine Usp Tablets Azathioprine Sodium Imuran Cyclosporine Sangcya Solution Oral; Gengraf Capsules Gold Chloride Gold Chloride Trihydrate Gold Sodium Thiomalate Myochrysine Hydroxychloroquine Hydroxychloroquine Sulfate; Plaquenil Leflunomide Arava Tablets Methotrexate† Rheumatrex Dose Pack†; Folex† Minocycline Minocycline Hydrochloride; Minocin Penicillamine Cuprimine Capsules Sulfasalazine Sulfasalazine *NDC codes are not displayed due to the excessive number † Methotrexate products were treated as a separate covariate

APPENDIX H. J-Codes Used to Define DMARD Treatment

J Code Code description J2910 Aurothioglucose J7501 Azathioprine parenteral 100 mg J7500 Azathioprine oral 50 mg J7516 Cyclosporine parenteral 250 mg J7502 Cyclosporine oral 100 mg J7515 Cyclosporine oral 25 mg J1600 Inj gold sodium thiomalate to 50 mg J8610 Methotrexate oral 2.5 mg† J9250 Methotrexate sodium 5 mg† J9260 Methotrexate sodium 50 mg† † Methotrexate products were treated as a separate covariate

The Degge Group, Ltd. 40 aTNF Switching Study 04/06/2018 APPENDIX I. Medications Used to Define Oral Corticosteroids*

Generic Dexamethasone Methylprednisolone Prednisolone Prednisone *NDC codes are not displayed due to the excessive number

The Degge Group, Ltd. 41 aTNF Switching Study 04/06/2018 APPENDIX J. Antidiabetic Drugs Used to Define History of Diabetes*

Generic Acarbose Acetohexamide Chlorpropamide Exenatide Glimepiride Glipizide Glucagon Glyburide Insulin Insulin Aspart Insulin Beef/Pork Insulin Bovine Insulin Detemir Insulin Glargine Recombinant Insulin Glulisine Recombinant Insulin Human Insulin I-131 Insulin Inhalation, Rapid Acting Insulin Lispro Recombinant Metformin Metformin-Rosiglitazone Miglitol Nateglinide Pioglitazone Pramlintide Acetate Repaglinide Rosiglitazone Maleate Sitagliptin Phosphate Tolazamide Tolbutamide Troglitazone *NDC codes are not displayed due to the excessive number

The Degge Group, Ltd. 42 aTNF Switching Study 04/06/2018 APPENDIX K. Medications Used to Define Asthma/COPD Treatment*

Generic Albuterol Albuterol Sulfate/Ipratropium Bromide Aminophylline Arformoterol Tartrate Beclomethasone Beclomethasone Dipropionate Budesonide Cromolyn Dextrose Dyphylline Flunisolide Fluticasone Propionate/Salmeterol Xinafoate Formoterol Formoterol Fumarate Ipratropium Bromide Isoproterenol Hydrochloride Levalbuterol Levalbuterol Tartrate Metaproterenol Mometasone Mometasone Furoate Montelukast Omalizumab Pirbuterol Salmeterol Salmeterol Xinafoate Terbutaline Theophylline Theophylline Calcium Salicylate Theophylline Sodium Glycinate Triamcinolone Triamcinolone Acetonide Zafirlukast Zileuton *NDC codes are not displayed due to the excessive number

The Degge Group, Ltd. 43 aTNF Switching Study 04/06/2018

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