Electronic Supplementary Material Table 1: Drugs and Chemicals Associated with Substantial

References Unsafe Previously unsafe, but probably

1,15 safe in therapeutic dose Anti-infective Dapsone Clorquine

Nitrofurantione (and related) Mepacrine

Primaquine Quinine

Pamaquine Sulfadimidine

Sulfanilamide Sulfasalazine

Sulfacetamide Aldesulfone

Sulfapyridine Glibenclamide

Sulfamethoxazole Co-trimoxazol

Ciprofloxacin

Levofloxacin

Nalidic acid

Norfloxacin

Ofloxain

Miscellaneous Acetanilide Asprin

Uricase (rasburicase, pegloticase) Acetaminophen

Phenazopyridine Antipyrin

Methylthioninium chloride (methylene Aminophenzone (and related

blue) NSAID’s)

Dimercaprol Ascorbic acid

Nalidixic acid Mesalazine

Niridazole Vitamin K analogues

Methylthionium Chloramphenicol Doxorubicin

Dimercaprol

Probenecid Chemicals and Fava beans Acalypha indica extract foods Aniline dyes

Naphthalene (mothballs, lavatory

deodorant)

Henna compounds (and related dyes

used for hair and tattoos)

2,4,6-trinitrotoluene

Electronic Supplementary Material Table 1: Drugs and chemicals associated with substantial hemolysis in patients with G6PD deficiency