Faculty of Science s1

F A C U L T Y O F S C I E N C E P . J . Š A F Á R I K U N I V E R S I T Y K O Š I C E , S L O V A K I A

A N N U A L R E P O R T 2 0 0 1

1 INTRODUCTION

The Faculty of Science of the P. J. Šafárik University in Košice was founded in 1963 and during its existence it has educated more than 4 000 graduates of both, joint and single degree programme study in all branches of natural science. The quality of its educational and research activities and involvement in the European scientific and higher education development programmes strengthen the chance of the Faculty to line up among respected European higher education institutions. The Institutional Development Programme includes the main recommendations and guiding principles conceived by the Joint Declaration of the European Ministers of Education convened in Bologna on June 19th, 1999 on "European space for higher education" and "World Declaration on Higher Education for the Twenty-first Century" as well as priorities stated by the representatives of the summit in Prague, 2001 entitled “Conference on European Higher Education”. In the frame of generally accepted model 3-5-8, the Faculty provides the Bachelor's and Master's degree study in the following branches: Biology, Chemistry, Environmental Ecology, Informatics, Mathematics and Physics as well as all joint degree programmes in combinations of Biology, Chemistry, Geography, Informatics, Mathematics and Physics making thus the offered range of natural science branches almost complete. Up to 10 per cent of the graduates take up doctoral study at the Faculty in one of the thirteen accredited fields of science. The graduates of the Faculty find employment not only as researchers and secondary school teachers but also adapt in the business sphere and public administration. Some of them successfully undertake doctoral study or postdoctoral training abroad to apply in the European labour market. New forms of further long-life education as a part of service to the society are provided not only for graduates of the Faculty of Science but also for public. The RNDr. (Rerum Naturalium Doctor) examinations, qualification examinations, various courses and training projects are to be mentioned. In accordance with the European documents on higher education the Faculty approached towards the fundamental reform of educational system by the implementation of the credit-based system in line with the European standard ECTS in the past years. Joining the European programme SOCRATES / ERASMUS promoted the possibility for students to undertake a fully recognized period of a study in EU as an integral part of their degree and academic qualification. The higher education at the Faculty of Science is provided on a research background closely interacting with domestic and foreign scientific and educational institutions. Up to 60 per cent of our scientific outputs are made within this co-operation. The research in the field of Biology, Ecology, and Geography is orientated on study of biodiversity of plants and animals, biotechnology of medicinal plants, carcinogenesis, prevention and cancer therapy, and relief evolution of the Slovak karst; in Chemistry on synthesis and properties of new compounds with biological activity and new materials; in Informatics on fuzzy techniques, neural networks and logical programming; in Mathematics on graph theory, algebraic structures, differential equations and topology; in Physics on development of new magnetic materials, theoretical and experimental research of low magnetism and quantum liquids at ultra-low temperatures, nuclear collision studies and photodynamic effect.

2 ACADEMIC OFFICIALS

Dean : Prof. Alexander Feher, DSc.

Vice - deans : Assoc. Prof. Eva Čellárová, PhD. (international relations)

Assoc. Prof. Ján Imrich, PhD. (research)

Assoc. Prof. Dušan Šveda, PhD. (academic affairs)

Chairman of Academic Senate : Assoc. Prof. Pavol Sovák, PhD.

Address : Faculty of Science P. J. Šafárik University Moyzesova 16 041 54 Košice Slovak Republic

Telephone : +421-55-6227665, 6222121-3 Fax : +421-55-6222124 E - mail : [email protected] http://www.science.upjs.sk

SCIENTIFIC BOARD

Chairman : Prof. Alexander Feher, DSc. (Department of Experimental Physics, Fac. Sci., P. J. Šafárik University)

Members : Prof. Eva Ahlersová, DSc. (Department of Animal and Human Physiology, Fac. Sci., P. J. Šafárik University) Prof. Andrej Bobák, DSc. (Department of Theoretical Physics and Geophysics, Fac. Sci., P. J. Šafárik University) MSc. Dušan Budzák (Research Institute for Man-Made Fibres, Svit) Prof. Lev Bukovský, DSc. (Department of Mathematical Informatics, Fac. Sci., P. J. Šafárik University) Assoc. Prof. Eva Čellárová, PhD. (Department of Experimental Botany and Genetics, Fac. Sci., P. J. Šafárik University) Assoc. Prof. Juraj Černák, PhD. (Department of Inorganic Chemistry, Fac. Sci., P. J. Šafárik University)

3 Prof. Slavko Chalupka, PhD. (Department of Theoretical Physics and Geophysics, Fac. Sci., P. J. Šafárik University) Prof. Pavol Dubinský, DSc. (Parasitological Institute of the Slovak Academy of Sciences, Košice) Prof. Milan Dzurilla, PhD. (Department of Organic Chemistry, Fac. Sci., P. J. Šafárik University) Assoc. Prof. Peter Fedoročko, PhD. (Department of Cell and Molecular Biology, Fac. Sci., P. J. Šafárik University) Prof. Karol Flórián, DSc. (Department of Physical and Analytical Chemistry, Fac. Sci., P. J. Šafárik University) Prof. Miriam Gálová, DSc. (Department of Physical and Analytical Chemistry, Fac. Sci., P. J. Šafárik University) Assoc. Prof. Viliam Geffert, DSc. (Department of Mathematical Informatics, Fac. Sci., P. J. Šafárik University) Assoc. Prof. Zdenko Hochmuth, PhD. (Department of Geography, Fac. Sci., P. J. Šafárik University) Assoc. Prof. Igor Hudec, PhD. (Department of Zoology and Ecology, Fac. Sci., P. J. Šafárik University) Assoc. Prof. Ján Imrich, PhD. (Department of Organic Chemistry, Fac. Sci., P. J. Šafárik University) Assoc. Prof. Peter Javorský, DSc. (Institute of Animal Physiology of the Slovak Academy of Sciences, Košice) MSc. Dušan Jeleň (Chemko Co., Strážske) Prof. Stanislav Jendroľ, DSc. (Department of Geometry and Algebra, Fac. Sci., P. J. Šafárik University) MSc. Peter Kavuľa (PV Trade Ltd., Košice) Assoc. Prof. Peter Kopčanský, PhD. (Institute of Experimental Physics of the Slovak Academy of Sciences, Košice) Assoc. Prof. Ivan Kútny, PhD. (Department of Humanities, Fac. Sci., P. J. Šafárik University) Prof. Ladislav Lovaš, PhD. (Faculty of Public Administration, P. J. Šafárik University) Prof. Gabriela Martinská, PhD. (Department of Nuclear Physics, Fac. Sci., P. J. Šafárik University) Prof. František Mihina, PhD. (Philosophical Faculty, University of Prešov, Prešov) Prof. Pavol Miškovský, DSc. (Department of Biophysics, Fac. Sci., P. J. Šafárik University) Prof. Eva Mišúrová, PhD. (Department of Cell and Molecular Biology, Fac. Sci., P. J. Šafárik University) Prof. Ľudovít Parilák, PhD. (Institute of Material Research of the Slovak Academy of Sciences, Košice) Prof. Dušan Podhradský, DSc. (Department of Biochemistry, Fac. Sci., P. J. Šafárik University) Prof. Branislav Rovan, PhD. (Faculty of Mathematics, Physics and Informatics, Comenius University, Bratislava) Assoc. Prof. Pavol Sovák, PhD. (Department of Experimental Physics, Fac. Sci., P. J. Šafárik University)

4 Prof. Vincent Šoltés, PhD. (Faculty of Economics, Technical University Košice) Assoc. Prof. Dušan Šveda, PhD. (Department of Mathematical Analysis, Fac. Sci., P. J. Šafárik University) Prof. Peter Vojtáš, DSc. (Department of Mathematical Informatics, Fac. Sci., P. J. Šafárik University)

STRUCTURE OF FACULTY

S E C T I O N S Biology Social and Chemistry Informatics Mathematics Physics Sciences Geography

Full - Time 3 4 2 1 5 0 Professors

Part -Time 2 2 0 0 2 0 Professors

Full - Time 10 13 2 12 14 2 Assoc. Prof.

Part - Time 2 2 1 5 0 0 Assoc. Prof.

Assistant 13 17 7 13 11 4 Professors

Senior 7 5 0 0 11 0 Researchers

Researchers 13 4 1 0 10 0

BIOLOGY Animal and Human Physiology and GEOGRAPHY Cell and Molecular Biology Experimental Botany and Genetics Geography Zoology and Ecology

5 CHEMISTRY Biochemistry Inorganic Chemistry Organic Chemistry Physical and Analytical Chemistry

INFORMATICS Centre of Applied Informatics Mathematical Informatics

MATHEMATICS Geometry and Algebra Mathematical Analysis

PHYSICS Biophysics Experimental Physics Nuclear Physics Theoretical Physics and Geophysics

DEPARTMENTS of Humanities SOCIAL SCIENCES Philosophy, Pedagogy and Psychology

RESEARCH HIGHLIGHTS

The Faculty of Science of the P. J. Šafárik University in Košice, in accord with a new Higher Education Act, belongs to a group of research faculties, which put a strong accent on research as an integral part of their mission. Multidisciplinary character of the Faculty of Science offers possibilities for interdisciplinary and multidisciplinary approach and integration of scientific activities. More than 170 university teachers and researchers together with about 100 doctoral students are involved in up to 70 scientific projects funded by domestic and foreign grant agencies, as Slovak Grant Agency for Science (VEGA), Slovak Cultural and Educational Agency (KEGA), NATO Research Foundation, DAAD (Germany), National Science Foundation (U.S.A.), and others. In last years, the Faculty keeps high volume and quality of scientific outputs. Excellence in research measured by international standards is a first objective of our research teams. In an applied research, main interest is devoted to pharmaceutical, pharmacological, chemical and material research. Performance of the Faculty scientific base compares favourably with the rest of Slovakia on a range of indicators. Continuing increase in funding streams for research due to the growing activity and per capita income from research grants and contracts prevails several times the average of the Slovak universities. The numbers of Faculty publications and citations in the last three years are shown below:

6 1999 2000 2001 Monographs and books 13 10 3 Textbooks 32 35 35 SCI papers 140 124 131 Non-SCI papers 60 79 75 Preprints and conference papers 115 175 116 Abstracts 178 118 189 Patents 6 0 0

1999 2000 2001 Citations total 588 745 623 SCI 363 445 371 Non-SCI 225 300 252

Impact factor of the Faculty (a number of SCI citations divided by a number of SCI papers) in 2001 reached the value 2.83 (2000 – 3.58, 1999 - 2.59).

DOCTORAL STUDY

The ambition of the Faculty is to provide, through a doctoral study, the stream of specialized and highly trained researchers able to undertake basic as well as applied research and development. To recruit and develop the next generation of researchers, the doctoral programmes have in 2001 been provided in following fields:

Analytical Chemistry Animal Physiology Biochemistry Biophysics Condensed Matter Physics and Acoustics Discrete Mathematics Genetics Inorganic Chemistry Mathematical Logics and Foundations of Mathematics Nuclear and Sub-nuclear Physics Organic Chemistry Programme and Information Systems Theory of Teaching of Mathematics Theory of Teaching of Physics

7 At the end of 2001 the Faculty had 57 internal doctoral students funded by the Ministry of Education and 50 external doctoral students, mostly employees of other universities and research institutions. Many doctoral students are supervised by individuals with top national and international reputations for their research and receive an excellent research training as a result. The scientific contributions of doctoral students represent a permanently increasing portion of the Faculty's scientific outputs. In 2001, 17 doctoral theses were defended. Along with research activities, doctoral students participate also in teaching.

EDUCATION

Throughout Slovakia, the Faculty belongs among pioneers in implementation of a credit- based system of a study, which was developed with help of EC projects (TEMPUS UM JEP 13050-98) and supported by a self-made information system (TEMPUS UM JEP 13401-98). With an aim to enlighten access to higher education to a larger number of applicants, almost 400 full-time undergraduate students were admitted to the Faculty in 2001. In last five years, the Faculty increased the number of students by more than 50 percent. The following teaching programmes are offered to them:

 Single (one-subject) programmes Biology with specialization in Animal and Human Physiology Cell and Molecular Biology Genetics and Plant Physiology Zoology and Ecology Chemistry with specialization in Biochemistry Inorganic Chemistry Organic Chemistry Physical and Analytical Chemistry Environmental Ecology with specialization in Chemistry in Environment Ecology Environmental Adaptation of Animals Environmental Science Informatics with specialization in Computer Systems and Networks Information and Knowledge Systems Mathematics with specialization in Financial and Insurance Mathematics Mathematical Informatics Mathematical Management Physics with specialization in Astronomy and Astrophysics Biophysics and Chemical Physics Nuclear Physics Physical Engineering of Materials Physics of Condensed Matter

 Joint (two-subject) programmes for teachers' preparation (combination of following subjects) Biology, Chemistry, Geography, Informatics, Mathematics, Physics, and Mathematics and Catechetics, Physics and Catechetics

8 Distribution of undergraduate students

Number of students

Joint (two-subject) Single program m es 500 402 400 300 219 200 174 165 151 154 200 130 145 92 100 59 67 16 0 s s y y s s s y r c y r c s s y y i i t t c c c g g i c c h i g i s s i i s t s t t o i o i t t p o l y l y l e a a a a a o h o h m h o m r i i m p m p e e c m c m b g b r r e h h e e e o o o t c f c f h h e . a t t n n g v i i c a a n m e m

9 AWARDS

Silinger prize 2001 awarded by the Slovak Botanical Society of Slovak Academy of Sciences for publication activities: Vanda Š v e h l í k o v á, Department of Experimental Botany and Genetics

Dean´s prize for science 2001, teachers and researchers

1. Prof. Stanislav J e n d r o ľ , DSc., Discrete Mathematics 2. Assoc. Prof. Vladimír L i s ý , PhD., Biophysics and Chemical Physics 3. Prof. Miriam G á l o v á, DSc. , Physical and Analytical Chemistry 4. Assoc. Prof. Miroslav R e p č á k , PhD., Plant Physiology

Dean´s prize for science 2001, doctoral students

1. Jozef H r i c, Biophysics 2. Erik B r u o t h, Discrete Mathematics 3. Bianka B o j k o v á, Physiology of Animals 3. Ivana D u n č k o v á, Theory of Teaching of Chemistry

10 APPOINTMENTS IN 2001

Professors

Andrej B o b á k , DSc. Professor of Physics since April 26, 2001

Pavol M i š k o v s k ý , DSc. Professor of Physics since April 26, 2001

Peter V o j t á š , DSc. Professor of Mathematical Informatics since April 26, 2001

Associate Professors

Gabriela A n d r e j k o v á , PhD. Assoc. Professor of Informatics since March 3, 2001

Zuzana D a x n e r o v á , PhD. Assoc. Professor of Biology since October 1, 2001

Matúš H a r m i n c , PhD. Assoc. Professor of Mathematics since April 1, 2001

Kvetoslava M a r k u š o v á , PhD. Assoc. Professor of Physical Chemistry since November 11, 2001

Božena M i h á l i k o v á, PhD. Assoc. Professor of Mathematics since April 1, 2001

Andrej O r i ň á k , PhD. Assoc. Professor of Analytical Chemistry since July 1, 2001

Associate Professors (external)

Dušan B r u n c k o , PhD. Assoc. Professor of Physics since February 15, 2001

Miroslav R e p i c k ý , PhD. Assoc. Professor of Mathematics since February 15, 2001

Doctor of Science

Villiam G e f f e r t , DSc. Doctor of Science in Theoretical Informatics since January 30, 2001

11 DOCTORAL THESES DEFENDED IN 2001

1. Tomáš Madaras – Discrete Mathematics „The structure of plane graphs“ 2. Mojmír Suchý – Organic Chemistry „Synthesis of some indole phytoalexins and relative compounds“ 3. Vladimír Kovaľ – Condensed Matter Physics and Acoustics „Electrophysical attributes and structure of piezoceramic matter“ 4. Marcel Morovský - Biochemistry „Bacteriocinic gram-positive rumen coccus“ 5. Vladimír Lacko – Discrete Mathematics „Persistency in combinatorial optimalization problems“ 6. Jozef Jirásek – Discrete Mathematics „Shrinkage of number of cycles in oriented graphs by rotation of edges“ 7. Erik Čižmár - Condensed Matter Physics and Acoustics „Contribution to the experimental study of non-linear magnetic excitations in selected low- dimensional magnetic systems“ 8. Slavomír Gabáni - Condensed Matter Physics and Acoustics „Study of metal attributes of 4f-electron systems in selected borides of precious solids at low temperatures“ 9. Anna Zorkovská - Condensed Matter Physics and Acoustics „Influence of substitutions on the structure and magnetic properties of Finemet“ 10. Oľga Fričová - Condensed Matter Physics and Acoustics „Study of modified polypropylene fibers with help of NMR and dynamic-mechanical methods“ 11. Norbert Popély – Mathematical Logics and Mathematical Foundations „Turing’s machinery with alternation“ 12. Peter Kubatka – Animal Physiology „Chemical prevention of mammary tumour of female rats using antiestrogens of raloxifen and pineal hormone melatonine variability of induction of experimental mammary carcinogenesis“ 13. Igor Majláth – Animal Physiology „Selected etiologic displays of Lacerta viridis, Laur. , 1768, in natural environment of Slovak karst“ 14. Katarína Kalická – Animal Physiology „Chemical prevention of mammary carcinogenesis using non-steroid antiflogistics (indometacine, nimezulide) and melatonine in female rats“ 15. Martina Chamilová – Animal Physiology „Metabolic changes in chemical prevention programs of mammary carcinogenesis induced in female rats“ 16. Marcel Török – Organic Chemistry „Experimental and theoretical study of intermolecular cyclization of some propenoylthioureas and Dimroth rearrangement of 1,3-thiazines“ 17. Pavol Bobík – Nuclear and Sub-nuclear Physics „Transition of cosmic radiation through magnetic sphere of Earth“

12 CONFERENCES ORGANISED BY THE FACULTY OF SCIENCE

"11th Czech and Slovak Conference on Magnetism" Košice, August 20-23, 2001

“Cycles & Colourings in Graphs ’2001” Stará Lesná, September 9-14, 2001

"Structure and Stability of Biomacromolecules SSB 2001" Košice, September 12-14, 2001

„Model of Science Teachers’ Further Education" Košice, September 19-21, 2001

"Environmental Education in Schools of Slovak Republic" Košice, December 6-7, 2001

13 S E C T I O N S a n d D E P A R T M E N T S

BIOLOGY and GEOGRAPHY

Department of Animal and Human Physiology

Mailing address: Department of Animal and Human Physiology Faculty of Science P. J. Šafárik University Moyzesova 11 041 67 Košice

Telephone: +421-55-6222610, 6222615, 6228656 Fax: +421-55-6222124 E-mail: [email protected]

Head of Department: Assoc. Prof. Beňadik Šmajda, PhD.

Full-time Professor: Eva Ahlersová, DSc.

Part-time Professor: Ivan Ahlers, DSc.

Full-time Assoc. Professors: Edita Paulíková, PhD. Beňadik Šmajda, PhD.

Assist. Professor: Peter Kubatka, PhD.

Senior Researcher: Igor Majláth, PhD.

Researchers: Bianka Bojková Mária Čermáková

Doctoral Students: Eva Adámeková Vladinmír Fekiač Martina Marková Erika Slivková

Home Collaboration : Educational and Counselling Centre of US Steel Košice, Košice-Šaca Neurobiological Institute, Slovak Academy of Sciences, Košice

Foreign Partners :

14 Chronobiology Laboratories, University of Minnesota, USA Institute of Oncology, St. Petersburg, Russia

Department of Cell and Molecular Biology

Mailing address: Department of Cell and Molecular Biology Faculty of Science P. J. Šafárik University Moyzesova 11 041 67 Košice

Telephone: +421-55-6228310, 6222610, 6222615, 6228656 Fax: +421-55-6222124 E-mail: [email protected]

Head of Department: Assoc. Prof. Peter Fedoročko, PhD.

Full-time Professor: Eva Mišúrová, PhD.

Full-time Assoc. Professors: Zuzana Daxnerová, PhD. Peter Fedoročko, PhD. Katarína Kropáčová, PhD.

Assist. Professors: Peter Solár, PhD. Mariana Kolesárová

Senior Researchers: Mária Kožurková, PhD. Nadežda Macková, PhD. Veronika Molnárová, PhD.

Researchers: Mariana Čekanová Viera Eliášová Mariana Kolesárová Lucia Slovinská

Doctoral Students: Beáta Falisová Štefánia Klimová Martina Regensbogenová

Home Collaboration : Institute of Veterinary Medicine, Košice L. Pasteur Medical Faculty Hospital, Košice Tissue Bank of the Burns Centre, US Steel Košice Hospital, Košice-Šaca Research Institute for Medicine, Modra

Foreign Partners : Intercell Biomedical Research and Development AG, Vienna, Austria

15 Institute of Biophysics, Academy of Sciences of the Czech Republic, Brno, Czech Republic Department of Molecular Virology, Baylor College of Medicine, Houston, USA

Department of Experimental Botany and Genetics

Mailing address: Department of Experimental Botany and Genetics Faculty of Science P. J. Šafárik University Mánesova 23 041 67 Košice

Head of Department: Assoc. Prof. Eva Čellárová, PhD.

Part-time Professor: Róbert Hončariv, PhD.

Full-time Assoc. Professors: Eva Čellárová, PhD. Katarína Kimáková, PhD. Pavol Mártonfi, PhD. Miroslav Repčák, PhD.

Assist. Professors: Martin Bačkor, PhD. Anna Macková, PhD. Katarína Bruňáková Patrícia Saxová

Senior Researchers: Anton Grejtovský, PhD. Jana Halušková, PhD.

Researchers: Adriana Eliášová Patrik Mráz Martina Urbanová

Doctoral Students: Zuzana Babincová Zuzana Jasenčáková Jana Koperdáková Ján Košuth Adriana Pastírová Adriana Pružinská Vanda Švehlíková

Home Collaboration : Faculty of Natural Sciences, Comenius University, Bratislava

16 Institute of Drugs Research, Modra Institute of Plants Genetics and Biotechnology, Slovak Academy of Sciences, Nitra Agricultural Farm, Stará Ľubovňa

Foreign Partners : University of Gent, Belgium Botanical Institute, Academy of Sciences of the Czech Republic, Pruhonice, Czech Republic Institute of Experimental Botany, Academy of Sciences of the Czech Republic, Olomouc, Czech Republic Agricultural Research Centre, Mikkeli, Finland University of Oulu, Finland Institute of Plant Genetics and Crop Plant Research, Gatersleben, Germany Institute of Resistance Genetics, Grünbach, Germany Faculty of Horticultural Science, Saint István University, Budapest, Hungary University of Szeged, Hungary Plant Research International, Wageningen, The Netherlands University of Nottingham, UK Florida Institute of Technology, Melbourne, USA

Department of Geography

Mailing address: Department of Geography Faculty of Science P. J. Šafárik University Jesenná 5 04154 Košice

Telephone: +421-55-6258594, 6221926 Fax: +421-55-6222124 E-mail: [email protected]

Head of Department: Assoc. Prof. Zdenko Hochmuth, PhD.

Full-time Professor: Ján Košťálik, DSc.

Full-time Assoc. Professor: Zdenko Hochmuth, PhD.

Assist. Professors: Dušan Barabas, PhD. Anton Fogaš Silvia Pavlíková Martin Rosič

Researcher: Jaroslava Harvanová

Home Collaboration : Slovak Speleological Society, Liptovský Mikuláš

17 Slovak Museum of Nature Protection and Speleology, Liptovský Mikuláš

Foreign Partners : Department of Physical Geography and Paleography, M. C. Sklodowska University, Lublin, Poland

Department of Zoology and Ecology

Mailing address: Department of Zoology and Ecology Faculty of Science P. J. Šafárik University Moyzesova 11 041 67 Košice

Head of Department: Assoc. Prof. Igor Hudec, PhD.

Part-time Assoc. Professors: Igor Hudec, PhD. Nadežda Stollárová, PhD.

Assist. Professors: Ľubomír Panigaj, PhD. Andrej Mock

Senior Researcher: Assoc. Prof. Kristína Chlebovská, PhD.

Researchers: Peter Ľuptáčik Milan Mešter Jozef Mižura

Doctoral Student: Zuzana Višňovská

Home Collaboration : Institute of Zoology, Slovak Academy of Sciences, Košice Parasitological Institute, Slovak Academy of Sciences, Košice

Foreign Partners : Faculty of Sciences, Charles University, Prague, Czech Republic Institute of Nature Conservation, Polish Academy of Sciences, Kraków, Poland

Research Projects

Antiestrogens in the combination with melatonin in the chemoprevention of mammary carcinogenesis in female rats. VEGA 1/7421/20 (Ivan Ahlers, 1/2000 - 12/2002)

18 The chemoprevention of mammary carcinogenesis in female rats by non-steroidal anti-inflammatory drugs in the combination with melatonin. VEGA 1/7397/20 (Eva Ahlersová, 1/2000 - 12/2002)

Heavy metal tolerance induction in the selected strains of lichen photobionts Trebouxia sp. - in vitro resynthesis of heavy metal tolerant lichen populations. VEGA 1/6029/99 (Martin Bačkor, 1/1999 - 12/2001) Genetic characteristics of genus Daphnia in Slovak dams. VEGA 2/6013/99 (Juraj Banykó, 1/1999 - 12/2001)

Genetic study of diploid genotypes of Hypericum perforatum L. at cell and molecular levels and effect of hypericin on radiosensitivity of cancer cells. VEGA 1/6028/99 (Eva Čellárová, 1/1999 - 12/2001)

Tumour cell and hemopoietic cell proliferation in mice after radiation therapy and/or immunotherapy under conditions of modulated eicosanoid metabolism. VEGA 1/6026/99 (Peter Fedoročko, 1/1999 - 12/2001)

Some responses of Chamomilla recutita (L.) Rausch. metabolism to heavy metals in soil. VEGA 1/6033/99 (Anton Grejtovský, 1/1999 - 12/2001)

Biosystematic study of some groups of the genus Hieracium sect. Alpina in Central Europe. VEGA 1/7558/20 (Patrik Mráz, 1/2000 - 12/2002)

Taxonomic revision of selected species of genera Veronica, Erophila, Melampyrum Erysimum, Senecio Thlaspi a Alyssum. VEGA 2/7081/20 (Pavol Mártonfi, 1/2000 - 12/2002)

The effect of some environmental genotoxic agents on the liver and kidney. VEGA 1/6030/99 (Eva Mišúrová, 1/1999 - 12/2001)

Evaluating the measure of influence of the water power station activities on biodiversity in Pieniny. VEGA 1/7559/20 (Ľubomír Panigaj, 1/2000 - 12/2002)

Stress secondary metabolites of Chamomilla recutita (L.) Rauschert. VEGA 1/7425/20 (Miroslav Repčák, 1/2000 - 2/2002)

The role of endogenous opiates in behavioural changes after irradiation in rats. VEGA 1/6425/99 (Beňadik Šmajda, 1/1999 - 12/2001)

The relief evolution in eastern part of Slovak Karst and surrounding parts of Volovské vrchy Mts. and Košice basin. VEGA 1/7396/20 (Zdenko Hochmuth, 1/2000 - 12/2002)

Recognize the beauty of the wild nature. KEGA project. (Róbert Hončariv, 7/1999 - 12/2001)

Assessment of performance: Physiological health and (epi) genetic stability. Quality enhancement of plant production through tissue culture. COST 843 (Eva Čellárová 10/2000-12/2004)

Development of medicine with an effective substance Vermikulin and use of medicinal plants. 02.04 Genetic aspects of hypericin synthesis in diploid genotypes of Hypericum perforatum L. and its hemopoietic and anticancer effects. R&D project 98-513-I-03/02-04 (Eva Čellárová, 1/1999 - 12/2001)

Development of medicine with an effective substance Vermikulin and use of medicinal plants. 02.01 Breeding and protection of medicinal plants. R&D project 98-513-I-03/02-01 (Miroslav Repčák, 1/1999 - 2/2001)

19 Selected results An antiestrogene of new generation, raloxifen was applied to female rats with N-methyl-N- nitrosourea induced carcinogenesis. This treatment, when given 2-times a week, decreased the incidence of mammary tumours by 67 % in comparison with controls and prolonged the latency of tumourigenesis (Kubatka et al., Neoplasma). The tamoxifen lowered the concentrations of cholesterol in serum and of triacylglycerols in the liver. The combined treatment with melatonin reduced the content of liver lipids (Chamilová et al., Biologia, VEGA 1/4721/20). The chemopreventive effect of indomethacin, a cyclooxygenase-1 inhibitor, was studied in experiments on Sprague-Dowley rats with 7,12-dimethylbenz(a)anthracene induced mammary carcinogenesis. A marked oncostatic effect of indomethacin alone or in combination with melatonin was found. After indomethacin treatment and after combined treatment with indomethacin and melatonin, a decrease in malonylaldehyde concentration in liver and in bone marrow of rats occurred (Môciková-Kalická et al., Folia Biol. (Praha), VEGA 1/7397/20). Ionizing radiation caused a decrease of nociception to heat stimuli in the hot-plate test in male Sprague-Dowley rats. This effect was blocked by naloxone, a blocator of the opioid μ- receptors. In the peripheral blood of irradiated rats a significant decrease of lymphocyte counts and an increase in neutrophiles occurred. These changes were reversed by a naloxone treatment (VEGA 1/6025/99). Proliferation of mouse fibrosarcoma cells G:5:113 was studied in vitro after affecting particular pathways of arachidonic acid metabolism by selected inhibitors. After 48h of cultivation nonspecific lipoxygenase inhibitors, nordihydroguaiaretic acid (NDGA) and esculetin, a specific 12-lipoxygenase inhibitor, baicalein, and inhibitor of five-lipoxygenase activating protein, MK-886, suppressed markedly the number of cells and induced significant changes in cell cycle distribution in a dose-dependent manner. While proadifen, an inhibitor of cytochrome P-450-monooxygenase, applied in low concentrations increased the cell number, at higher concentrations it inhibited cell proliferation and significantly changed the cell cycle. Cyclooxygenase inhibitors, ibuprofen, flurbiprofen and diclofenac suppressed cell number only moderately without any changes in the cell cycle. The occurrence of apoptosis was not significant for any of the selected drugs in comparison with untreated control cells. Moreover, not even one of the drugs caused the specific cleavage of poly(ADP-ribose)polymerase to the 89-kDa fragment, however, a decrease in total amount of this protein was observed after treatment with NDGA and esculetin (Hoferová et al., submitted, VEGA 1/6026/99). In the area of plant molecular biology and molecular cytogenetics the emphasis was given on the study the role of active oxygen species in plants, their reactive nature, cellular source and role in plant defense and morphogenetic responses (Vranová et al., J. Exp. Bot.). Studies on the cell cycle were focused on determination of a relation between chromatin organization and replication/histone acetylation (Jasenčáková et al., Chromosoma). New evidence of the reproduction diversity in Hypericum perforatum that was reconstructed from flow-cytometry data brought novel strategies to manage apomixis in plants (Matzk et al., The Plant J.). Simultaneously, genealogical lines consisting of four generations of somaclones and their progenies in Hypericum perforatum were subjected to genetic analysis of inheritance of some reproduction patterns that have been found as ploidy-dependent. Molecular analysis of cryopreserved Hypericum perforatum L. meristems brought evidence on DNA stability in the studied regions (VEGA1/6028/99). The results of botanical research contributed to the knowledge on genetic variability of taxons within the Hieracium section by determination of their chromosome numbers and mode of reproduction (Mráz, Folia Geobot.). Identification of umbelliferone as a stress metabolite in Chamomilla recutita (Repčák et al., J. Plant Physiol.) and its accumulation under abiotic stress and new evidence on the uptake and

20 accumulation of mobile forms of heavy metals contributed to the knowledge in the area of plant physiology.

Selected publications

1. Čavarga I., Brezáni P., Čekanová-Figurová M., Solár P., Fedoročko P., Miškovský P.: Photodynamic therapy of murine fibrosarcoma with a topical and systemic administration of Hypericin. Phytomedicine 8, 325-330, 2001 2. Chamilová M., Bojková B., Kalická K., Kubatka P., Adámeková E., Ahlersová E., Ahlers I., Pástorová B. : Retinyl acetate and melatonin in chemoprevention of mammary carcinogenesis in female rats: metabolic changes. Acta Vet. (Brno) 70, 57-63, 2001 3. Chamilová M., Bojková B., Kubatka P., Kalická K., Adámeková E., Ahlers I., Ahlersová E.: Prevention of N-methyl-N-nitrosourea-induced mammary carcinogenesis in female rats by tamoxifen and melatonin: metabolic alterations. Biologia 56, 565-571, 2001 4. Grejtovský A., Repčák M., Eliašová A., Markušová K. : Effect of cadmium on active principle contents of Matricaria recutita. L. Herba Polonica 47, 203-208, 2001 5. Jasenčáková Z., Meister A., Schubert I.: Chromatin organization and its relation to replication and histone acetylation during the cell cycle in barley. Chromosoma 110, 83-92, 2001 6. Kováč, ľ.,Ľuptáčk, P., Miklisová, D.: Soil Oribatida and Collembola communities across a land depression in an arable field. Eur. J. Soil. Biol. 37, 1-5, 2001 7. Kubatka P., Bojková B., Kalická K., Chamilová M., Adámeková E., Ahlers I., Ahlersová E., Čermáková M.: Preventive effects of raloxifene and melatonin in N-methyl-N-nitrosourea-induced mammary carcinogenesis in female rats. Neoplasma 48, 313-319, 2001 8. Kubatka P., Bojková B., Môciková-Kalická K., Mníchová-Chamilová M., Adámeková E., Ahlers I., Ahlersová E., Čermáková M.: Effects of tamoxifen and melatonin on mammary gland cancer induced by N-methyl- N-nitrosourea and by 7,12- dimethylbenz(a)anthracene, respectively, in female Sprague–Dawley rats. Folia Biol. (Praha) 47, 5-10, 2001 9. Marhold K., Mártonfi P.: Typification of two Linnaean species names of the genus Thlaspi (Brassicaceae). Novon 11, 189-192, 2001 10. Mártonfi P., Repčák M., Ciccarelli D., Garbari F.: Hypericum perforatum L. – chemotype without rutin from Italy. Biochem. Syst. Ecol. 29, 659-661, 2001 11. Mártonfi P.: New species of the genus Hypericum sect. Hypericum (Guttiferae) from Slovakia. Folia Geobot. 36, 371-384, 2001 12. Matzk F., Meister A., Brutovská R., Schubert I.: Reconstruction of reproductive diversity in Hypericum perforatum L.opens novel strategies to manage apomixis. The Plant J. 26, 275-282, 2001 13. Mníchová M., Môciková K., Kubatka P., Bojková B., Ahlers I., Ahlersová E.: Metabolic changes in mammary carcinogenesis induced in female rats by irradiation and DMBA administration: the effect of melatonin in a chemoprevention project. Biologia 56, 225-230, 2001 14. Môciková-Kalická K., Bojková B., Adámeková E., Mníchová-Chamilová M., Kubatka P., Ahlersová E., Ahlers I.: Preventive effects of indomethacin and melatonin on 7, 12-dimethylbenz(a)anthracene-induced mammary carcinogenesis in female Sprague-Dawley rats. A preliminary report. Folia Biol. 47, 75-79, 2001 15. Mock A.: Millipedes (Diplopoda) in hothouses – first records from Slovakia. Biologia 56, 468-472, 2001 16. Mráz P., Chrtek J., Kirschner J.:

21 Genetic variation in the Hieracium rohacsense group (Hieracium sect. Alpina). Phyton. Horn. 41, 109-116, 2001 17. Mráz P.: Chromosome numbers in selected species of Hieracium sect. Alpina (Asteraceae) from Central and Eastern Europe. Folia Geobot. 36, 321-332, 2001 18. Pristaš, P., Molnárová, V., Javorský, P.: Restriction and modification systems of ruminal bacteria. Fol. Microbiol. 46, 71-72, 2001 19. Repčák M., Imrich J., Franeková M.: Umbelliferone, a stress metabolite of Chamomilla recutita (L.) Rauschert. J. Plant Physiol. 158, 1085-1087, 2001 20. Repčák M., Pastírová A., Imrich J., Švehlíková V., Mártonfi P.: The variability of (Z)- and (E)-2-β-D-glucopyranosyloxy-4-methoxy cinnamic acids and apigenin glucosides in diploid and tetraploid Chamomilla recutita. Plant Breeding 120, 188-190, 2001 21. Repčák M., Pastírová A., Švehlíková V., Mártonfi P.: Quantity pattern of the main phenolic compounds in the tetraploid Chamomilla recutita. Biologia, 56, 455-457, 2001 22. Slovinská L., Kropáčová K., Kolesárová M., Mišúrová E.: Effects of combined treatment of rats with cadmium and ionizing radiation on nucleic acids in the kidneys, liver and haemopoietic organs. Folia Biol. 47, 92-100, 2001 23. Smilde W. D., Halušková J., Sasaki T., Graner A.: New evidence for the synteny of rice chromosome 1 and barley chromosome 3H from rice expressed sequence tags. Genome 44, 361-367, 2001 24. Tajovský, K., Mock, A., Krumpál, M.: Millipedes (Diplopoda) in the birds´ nests in Slovakia. Eur. J. Soil. Biol. 37, 2001 25. Van Breusegem F., Vranová E., Dat J. F., Inzé D.: The role of active oxygen species in plant signal transduction. Plant Sci. 161, 405-414, 2001 26. Vranová E., Tähtiharu S., Rutchadaporn S., Willekens H., Heino P., Palva E. T., Inzé D., van Camp W.: The AKT3 potassium channel protein interacts with the AtPP2CA protein phosphatase 2C. J. Exp. Bot. 52, 181-182, 2001

22 CHEMISTRY

Department of Biochemistry

Mailing address: Department of Biochemistry Faculty of Science P. J. Šafarik University Moyzesova 11 04167 Košice

Head of Department: Assoc. Prof. Marián Antalík, PhD.

Part-time Professor: Dušan Podhradský, DSc.

Part-time Assoc. Professor: Marián Antalík, PhD.

Assist. Professors: Erik Sedlák, PhD. Viktor Víglaský, PhD. Nataša Tomášková - Mernik

Researchers: Danica Sabolová Eva Valušová

Doctoral Students: Jozef Adamčík Mária Neužilová Marek Stupák Rastislav Varhač

Home Collaboration : Institute of Experimental Physics, Slovak Academy of Sciences, Košice Institute of Physiology of Livestock, Slovak Academy of Sciences, Košice

Foreign Partners : Institute of Biophysics, Academy of Sciences of the Czech Republic, Brno, Czech Republic Department of Biochemistry, University of Bayreuth, Bayreuth, Germany Department of Biochemistry, University Texas Health Science Center, San Antonio, USA Department of Human Biol. Chem. Genetics, University Texas, Medical Branch, Galveston, USA

23 Department of Inorganic Chemistry

Mailing address: Department of Inorganic Chemistry Faculty of Science P. J. Šafárik University Moyzesova 11 04167 Košice

Head of Department: Assoc. Prof. Juraj Černák, PhD.

Full-time Professor: Katarína Györyová, DSc.

Full-time Assoc. Professors: Juraj Černák, PhD. Jozef Chomič, PhD. Mária Ganajová, PhD. Mária Reháková, PhD.

Assist. Professors: Ján Bubanec, PhD. Magdaléna Dzurillová, PhD. Ivan Potočňák, PhD. Vladimír Zeleňák, PhD. Zuzana Vargová

Doctoral Students: Erika Andogová Silvia Čuvanová Ivana Gibalová Juraj Kuchár Jana Paharová Mária Szakácsová Ľubica Triščíková

Home Collaboration : Matej Bel University, Banská Bystrica Faculty of Science, Comenius University, Bratislava Faculty of Chemical Technology, Slovak Technical University, Bratislava Institute of Material Research, Slovak Academy of Sciences, Košice Technical University, Košice

Foreign Partners : Pedagogical Academy, Graz, Austria

24 Pedagogical Academy, Wien, Austria Pedagogical Institute, Linz, Austria Faculty of Science, Charles University, Prague, Czech Republic Institute of Inorganic Chemistry, Institute of Macromolecular Chemistry, Institute of Physical Chemistry, Academy of Sciences of the Czech Republic, Prague, Czech Republic Masaryk University, Brno, Czech Republic University of Cairo, Egypt University Poitiers, France University Bayreuth, Germany University Halle, Germany Philipps-University, Marburg, Germany University Catania, Italy University Peruggia, Italy University of Gainesville, USA

Department of Organic Chemistry

Mailing address: Department of Organic Chemistry Faculty of Science P. J. Šafárik University Moyzesova 11 04167 Košice

Telephone: +421-55-6228332, 6228114, 6226317, 6222610, 6228656-57 Fax: +421-55-6222124 E-mail: [email protected]

Head of Department: Assoc. Prof. Jozef Gonda, PhD.

Full-time Professors: Milan Dzurilla, PhD. Pavol Kristian, DSc.

Full-time Assoc. Professors: Juraj Bernát, PhD. Jozef Gonda, PhD. Oľga Hritzová, PhD. Peter Kutschy, PhD. Gejza Suchár, PhD.

Assist. Professor: Dušan Koščík, PhD.

Senior Researchers: Assoc. Prof. Ján Imrich, PhD. Ivan Danihel, PhD. Miroslava Martinková, PhD. Marcel Török, PhD. Mojmír Suchý, PhD.

Researcher: Beáta Mátheová

25 Doctoral Students: Eva Bálentová Patrik Čonka Zuzana Čurilová Imrich Géci Peter Ivanko Martin Humeník Ladislav Janovec Miroslava Magurová Renáta Marušková Mária Vilková Martin Walko Janka Záletová

Home Collaboration : Department of Organic Chemistry, Comenius University, Bratislava Department of Organic Chemistry, Slovak Technical University, Bratislava Georganics Co., Bratislava Institute of Chemistry, Slovak Academy of Sciences, Bratislava Merck Ind-Lab, Co., Bratislava Research Institute for Soil Fertility, Bratislava Synkola Co., Bratislava Rhodia Industrial Yarns Slovakia, Co., Humenné TEHO Co., Košice Domsprav, Co., Michalovce CHEMKO, Co., Strážske

Foreign Partners : Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague, Czech Republic Department of Inorganic Chemistry, Charles University, Prague, Czech Republic Department of Chemistry, University of Turku, Finland Institute for Chemical Reaction Science, Tohoku University, Sendai, Japan Novartis AG, Switzerland Syngenta/Novartis AG, Basel, Switzerland

Department of Physical and Analytical Chemistry

Mailing address: Department of Physical and Analytical Chemistry Faculty of Science P. J. Šafárik University Moyzesova 11 04167 Košice

Telephone: + 421-55-6222605, 6228114, 6226317, 6222610, 6228656 Fax: + 421-55-6222124 E-mail: [email protected]

Head of Department: Prof. Karol Flórián, DSc.

26 Full-time Professor: Miriam Gálová, DSc.

Part-time Professor: Karol Flórián, DSc.

Full-time Assoc. Professors: Milan Brutovský, PhD. Adam Košturiak, PhD. Ander Oriňák, PhD. Kvetoslava Markušová, PhD.

Part-time Assoc. Professor: Vasiľ Andruch, PhD.

Assist. Professors: Taťána Gondová, PhD. Daniela Kládeková, PhD. Renáta Oriňáková, PhD. František Kaľavský Pavol Meľuch Ján Novák Katarína Reiffová Viera Vojteková

Researcher: Andrea Turoňová

Doctoral Students: Miroslav Gál Martina Justinová Marcel Michlovič Monika Telepčáková Zdeněk Tokár

Home Collaboration : Department of Physical Chemistry, Department of Analytical Chemistry, Comenius University, Bratislava. HSC Service Co., Bratislava Research Institute for Soil Fertility, Bratislava Institute of Material Research, Slovak Academy of Sciences, Košice Faculty of Metallurgy, Technical University, Košice

Foreign Partners : J. Heyrovský Institute of Physical Chemistry and Electrochemistry, Academy of Sciences of the Czech Republic, Prague, Czech Republic Institute of Inorganic Chemistry, Academy of Sciences of the Czech Republic, Řež, Czech Republic Department of Chemical Technology and Environmental Chemistry, L. Eötvös University, Budapest, Hungary School of Chemistry and Geology, G. Mercator University, Duisburg, Germany Institute of Inorganic and Analytic Chemistry, F. Schiller University, Jena, Germany Institute of Chemistry, Ernst-Moritz-Arndt-University, Greifswald, Germany

Research Projects

Cyanocomplexes as low dimensional magnetic materials: Preparation, structure and magnetic properties. VEGA 1/7426/20

27 (Juraj Černák, 1/2000 - 12/2002)

Application of electrochemical procedures for alloying and characterization of dispersed materials used in powder metallurgy. VEGA 1/6024/99 (Miriam Gálová, 1/1999 - 12/2001)

Stereoselective synthesis of nucleoside antibiotics and analogues of the polyoxins, nikkomycins and phytoalexine group. VEGA 1/6080/99 (Jozef Gonda, 1/1999 - 12/2001)

New ways to syntheses of biologically interesting acridinyl and anthracenyl derivatives. VEGA 1/6077/99 (Ján Imrich, 1/1999 - 12/2001)

New and unconventional magnetic materials. VEGA 1/6079/99 (Adam Košturiak, 1/1999 - 12/2001)

The stability of nucleic acids and complexes of nucleic acids with proteins. VEGA 1/8047/01 (Dušan Podhradský, 1/2001 - 12/2003)

Materials on the basis of inclusion compounds, their properties and possibility of applications VEGA 1/8049/01 (Mária Reháková, 1/2001 – 12/2003)

Model of science teachers´ further education. Tempus Phare AC JEP 14327-1999 (Mária Ganajová, 2001 – 2002)

Evaluation, optimisation and validation of solid-sampling methods of analysis. Slovak-German project. (Karol Flórián, 5/1999 - 12/2001)

Investigations on structure and properties of acridine and flavonoid derivatives with anti - cancer and anti - Alzheimer activity. Slovak-Finnish project. (Ján Imrich, 1/2000 - 12/2002)

Selected Results

In biochemistry, a problem of heat stress on distribution of plazmide DNA from z E. coli was studied. Increasing the temperature lowers a number of superhelical topoisomers. At higher temperatures new alternative structures untypical for mesophilic organisms are arising (Sedlák et al., Biochemistry). Stability of elongation factor Ts from Thermus thermophilus consisting of two antiparalel beta- sheets connected by central disulfide bond was studied by calorimetry and circular dichroism in presence or absence of the disulfide bond. The fraction of van't Hoff a calorimetric enthalpy (delta H(vH) / delta H(cal)) shows that EF-Ts undergoes a thermal unfolding as a dimer independently on the -S-S- bond. A physiological application of the dimer structure of EF-Ts is possible (VEGA 1/8047/01). Research in inorganic chemistry included preparation of new homo- and heterobimetalic coordination compounds with cyano ligands and a correlation study of their magnetic and structural properties (Černák et al., Inorg. Chim. Acta, Monatsh. Chem.). Magnetostructural correlations in the selected transition metal tetracyanonickelnatanes possessing chain structure have been experimentally investigated. It was shown that the compounds containing non-magnetic transition metal in the exchange bridge are characterized by a low value of exchange coupling constant (Černák et al., Coord. Chem. Rev., VEGA 1/7426/20). Summation, comparison and choice of the best criterion for determination of the shape of coordination polyeders of pentacoordinated copper compounds with N-donor ligands was done and

28 verified on compounds containing bromide and chloride anions. (Potočňák, VEGA 1/6106/99). New information on properties and application possibility of zeolite and clinoptilolite materials were acquired (Reháková, VEGA 1/8049/01). Next, new complexes of zinc carboxylates with bioactive compounds (e.g. theophyline, nicotine amide) were prepared. Their thermal, spectral and structural properties and biological activity towards bacteria and fungi were determined. In organic chemistry, new original methods of synthesis of plant antimicrobial secondary metabolites - phytoalexins were elaborated, and resulting products were used in studies of convergent synthesis of nucleosides. Thus, stereochemical studies of a cruciferous oxindole phytoalexin, spirobrassinin and its spirooxazoline analogue were carried out (Suchý et al., J. Org. Chem.). A new original synthesis of indole phytoalexin cyclobrassinon and some its analogues, possessing 1,3-thiazino(6,5-b)indol-4-one tricyclic ring system was performed by various ways (Suchý et al., Tetrahedron Lett., Kutschy et al., Tetrahedron Lett.). Natural phytoalexin camalexin with antifungal and antitumour activity was prepared by a new method (Dzurilla et al., Molecules, VEGA 1/6080/99). New stereoselective syntheses of a nucleoside part of antibiotics polyoxine J, nikkomycine B and linkosamine, based on (3,3)-sigmatropic rearrangements of trihalogenacetimidates and allylthiocyanates derived from D-ribose, uridine and D-galactose, were elaborated (Gonda et al., Tetrahedron Lett.) The stereoselective ketene Claisen rearrangement of chiral 5-isopropylsulfanyl- 3-penten-2-amines was interpreted using a semiempirical AM1 method (Gonda, Martinková, Ernst, Belluš, Tetrahedron). A new stereoselective „domino“ reaction composed of two subsequent reactions: a (3,3)-sigmatropic rearrangement of allylthiocyanates and following intermolecular heterocyclization was developed. This method allows a stereocontrolled synthesis of enantiomerically pure 2,3-diaminocarboxylic acids or compounds with 1,2-diamine fragment (Gonda, Martinková, Imrich, Tetrahedron, in press, VEGA 1/6080/99). Utilization of a specific reactivity of the C-9 acridine carbon in 9-isothiocyanatoacridine derivatives allowed preparing a broad series of new spiroheterocyclic derivatives containing 9,10- dihydroacridine skeleton (spirotriazolines, thiazolidinones and thiazolines) with antibacterial and antitumour activity. As the most important, the synthesis of polycyclic derivatives containing spirodihydroacridine, imidazole a thiazole skeleton was achieved (Klika et al., J. Org. Chem.). New highly fluorescent N-(10-metylacridinium-9-yl)thiourethanes, applicable as biomarkers of aminoacids and peptides were prepared from 10-metyl-9-isothiocyanatoacridiniumtriflate (Kristian et al., Heterocycles). X-Ray structural parameters of 9-isothiocyanatoacridine were confirmed and compared with those obtained by AM1, PM3 and ab initio calculations (Danihel et al., Chem. Pap.). New general method for synthesis of regioisomeric 3-R-2-iminothiazolidin-4-ones with high regioselectivity was elaborated and applied for synthesis of anthracenyl thiazolidinones (VEGA 1/6077/99). In physical chemistry, reactivity of an activated and passivated powder iron surface was derived from the rate of its electrochemical dissolving. A corrosion potential of Fe powders was established and the correlation between the reactivity of the powder surface and rate constants of Ni electroplating was found (Gálová et al., Partic. Sci. Technol., VEGA 1/6024/99) Substituted derivatives of phenyliminoxindole as materials applicable in electronics and analytical chemistry were synthesized on the basis of isatine. Influence of thin surface layers with anticorrosion, insulating and magnetic properties on macroscopic magnetic characteristics of amorphous metal bands was studied (Valko et al., Acta Phys. Slov., VEGA 1/6079/99). In didactics of chemistry, a "Model of Further Education of Teachers of Science Subjects" and supporting freeware "School information service for chemistry" as a part the Slovak national project INFOVEK for teachers of chemistry was elaborated. Educational courses "Multimedia and learning in chemistry supported by computer", "Environmental education in chemistry" and "Chemistry of

29 everyday life" were organized, as well. (Ganajová et al., http://kekule.science.upjs.sk, Tempus AC_JEP 14327-1999)

1. Bágeľová J. Gažová Z. Antalík M: Conformational stability of ferricytochrome c near the heme in its complex with heparin in alkaline pH. Carbohyd. Polym. 45, 227-232, 2001 2. Černák J, Lipkowski J., Potočňák I. Hudák A.: Bis-{bis(1,3-diaminopropane)copper(II) tetracyanonickellate(II)} tetrahydrate: Preparation, characterisation and crystal structure of a novel molecular tetracyanonickellate. Monatsh. Chem. 132, 193-202, 2001 3. Černák J., Orendáč M., Potočňák I., Chomič J., Orendáčová A., Skoršepa J., Feher A.: Cyanocomplexes with one-dimensional structure: Preparation, crystal structure and magnetic properties. Coordin. Chem. Rev. 224, 51-66, 2001 4. Černák J., Skoršepa J., Abboud K.A., Meisel M.W., Orendáč M., Orendáčová A., Feher A.: Preparation, crystal structure and magnetic properties of Cu(en)2Pd(CN)4 . Inorg. Chim. Acta 326, 3-8, 2001 5. Danihel I., Böhm S., Bušová T.: Acridin-9-yl isothiocyanate: Comparison of structural parameters from quantum-chemical calculations with corresponding X-ray data. Chem. Pap. 55, 113-117, 2001 6. Dzurilla M., Kutschy P., Záletová J., Ružinský M., Kováčik V.: Synthesis of camalexin. Molecules 6, 716-720, 2001 7. Flórián K., Hassler J., Förster O. : A long-term validation of the modernised DC-ARC-OES solid-sample method . Fresen. J. Anal. Chem. 371, 1047-1051, 2001 8. Gálová M., Oriňáková R., Grygar T., Lux L., Heželová M. : Relation between the dissolution reactivity of powder substances and efficiency of their electroplating. Particul. Sci. Technol. 19, 85-94, 2001 9. Gonda J., Martinková M., Ernst B., Belluš D.: 1,2-Asymmetric induction in the ketene Claisen rearrangement of (2S,3E)-5-isopropylsulfanyl)-3-pentenes. Tetrahedron 57, 5607-5613, 2001 10. Gonda, J., Martinková M., Walko M., Závacká E., Budešínsky M., Cisarová I.: Stereoselective synthesis of the 5`-aminofuranoside part of polyoxins via (3,3)-sigmatropic rearrangement of allylic thiocyanates. Tetrahedron Lett., 42, 4401-4404, 2001 11. Imrich J., Bernát J. , Kristian P., Klika K.D., Pihlaja K., Balentová E., Vilková M.: Synthesis of new spiro dihydroacridines from 9-substituted acridinyl synthons. Chem. Listy 95, 753-754, 2001 12. Klika K.D., Bernát J., Imrich J., Chomča I., Sillanpää R., Pihlaja K.: Unexpected formation of a spiro acridine and fused ring system from the reaction between an N-acridinylmethyl- substituted thiourea and bromoacetonitrile under basic conditions. J. Org. Chem. 66, 4416-4418, 2001 13. Kristian P., Bernát J., Imrich J., Sedlák E., Alföldi J., Čornanič M.: New approach to synthesis of N-substituted 9-amino/iminoacridines with important fluorescence properties. Heterocycles 55, 279-290, 2001 14. Kutschy P., Suchý M., Andreani A., Dzurilla M., Rossi M.: A new photocyclization approach to the rare 1,3-thiazino[6,5-b]indol-4-one derivatives. Tetrahedron Lett. 42, 9281-9283, 2001 15. Morovský, M., Pristaš, P., Javorský, P.: Bacteriocins of ruminal bacteria. Folia. Microbiol. 46, 61-62, 2001 16. Morovský, M., Pristaš, P., Javorský, P., Nes, I.F., Holo, H.: Isolation and characterization of enterocin BC25 and occurrence of the entA gene among ruminal gram-positive cocci.

30 Microbiol. Res. 156, , 1-006, 2001 17. Potočňák I., Dunaj-Jurčo M., Mikloš D., Jäger L.: Crystal structure of bis(2,2'-bipyridine-N,N')(dicyanamide-N)copper(II) tricyanomethanide. Electronic and structural parameters describing the shape of coordination polyhedra in five- coordinated copper(II) compounds. Monatsh. Chem. 132, 315-327, 2001 18. Potočňák I., Dunaj-Jurčo M., Mikloš D., Massa W., Jäger L.: Bis(2,2'-bipyridine) (dicyanamido) copper (II) tetrafluoroborate. Acta Crystallogr. C57, 363-365, 2001 19. Reháková M.,Wadsten T., Nagyová S., Bastl Z., Briančin J: Study of copper forms of synthetic zeolite ZSM5 containing ethylenediamine. J. Incl. Phenom. 39, 181-186, 2001 20. Sedlák E., Valušová E., Nesper-Brock, M., Antalík M., Sprinzl M.: Effect of the central disulfide bond on the unfolding behaviour of elongation factor Ts from Thermus thermophilus. Biochemistry 40, 9579-9586, 2001 21. Suchý M., Kutschy P., Dzurilla M., Kováčik V., Andreani A., Alfőldi J.: 1,3-Thiazino[6,5-b]indol- 4-one derivatives. The first synthesis of indole phytoalexin cyclobrassinon. Tetrahedron Lett. 42, 6961-6963, 2001 22. Suchý M., Kutschy P., Monde K., Goto H., Harada N., Takasugi M., Dzurilla M., Balentová E.: Synthesis, absolute configuration, and enantiomeric enrichment of a cruciferous phytoalexin, (S)-(-)- spirobrassinin, and its oxazoline analog. J. Org. Chem. 66, 3940-3947, 2001 23. Turoňová A., Gálová M., Lux L., Gál M. : Electrochemical processes during plating Fe powder particles by Ni and Ni/Cu coating in the fluidized bed. J. Solid State Electrochem. 5, 502-506, 2001 24. Valko L., Hurta E., Valko M., Sláma J., Košturiak A.: Binuclear iron Fe(II) 3-semicarbazone-2,3-dioxoindole complexes as potential organic ferromagnetics. Acta Phys. Slov. 51, 281-287, 2001 25. Valušová, E., Sedlák, E., Antalík, M., Nock, S. & Sprinzl, M.: Effect of N-domain on the stability of elongation factor Ts from Thermus thermophilus. Biochim. Biophys. Acta, Protein Struct. Mol. Enzymol. 1547, 117-126, 2001 26. Zeleňák, V., Győryová, K., Čečková, M.: Spectral, thermoanalytical and XRD study of zinc(II) complexes containing adenine and guanosine. Thermochim. Acta 371, 103-109, 2001

31 INFORMATICS

Department of Mathematical Informatics

Mailing address: Department of Mathematical Informatics Faculty of Science P. J. Šafárik University Jesenná 5 / Park Angelinum 9 04154 Košice

Telephone: +421-55-6220949, 6221128-29, 6222971, 6221926-28 Fax: +421-55-6222124 E-mail: [email protected]

Head of Department: Prof. Peter Vojtáš, DSc.

Full-Time Professors: Lev Bukovský, DSc. Peter Vojtáš, DSc.

Full-Time Assoc. Professors: Gabriela Andrejková, PhD. Viliam Geffert, DSc.

Visiting Assoc. Professor: Andrej Kyselovič, PhD.

Assist. Professors: Jozef Jirásek, PhD. Stanislav Krajči, PhD. Norbert Popély, PhD. Jozef Studenovský, PhD. Jan Vinař, PhD. Rastislav Lencses Milan Schmotzer

Researcher: Marián Andrejko

Doctoral Students: Ľubomíra Ištoňová Eva Jenčušová Marcel Mojžiš Ondrej Štibrík Eva Trenklerová

32 Home Collaboration : VSL Software Ltd., Košice US Steel Košice, Educational and Counselling Centre, Košice US Steel Košice, Informatics Co., Košice

Research Projects

Structure of some objects of real analysis studied by set-theoretical methods. VEGA 1/7555/20 (Lev Bukovský, 1/2000 - 12/2002)

Combinatorial structures and complexity of algorithms. VEGA 1/7465/20 (Viliam Geffert, 1/2000 - 12/2002)

Semantics, analysis and design of flexible query answering system over databases enhanced by fuzzy logic knowledge base. VEGA 1/7557/20 (Peter Vojtáš, 1/2000 - 12/2002)

Preparation of teachers from primary and secondary schools and high of schools to create self-made hypermedia teaching materials. KEGA 255/2000 (Gabriela Andrejková, 1/2000 - 12/2001)

Set-theoretical aspects of the theory of real functions. NATO PST.CLG.977652 (Lev Bukovský, 3/2001 - 3/2003)

Selected Results

Soundness and completeness of fuzzy logic programming was demonstrated and an adequate data model found. Also, the source of discontinuity in GAP programs was identified and a variant with continuous semantics proposed. For finding the string most similar to the common subsequence of fuzzy sets, algorithms for fuzzy set operations and a time polynomial algorithm were created. Next, incremental neural networks for predicting special functions were designed. Results were demonstrated and graph algorithms designed and implemented for reducing the number of cycles in directed graphs by changing edge direction (with an application to computer networks), (Vojtáš, Fuzzy Set Syst., VEGA 1/7557/20).

33 It was shown that, on inputs of length exceeding 5n^2, any n-state unary 2nfa (two-way nondeterministic finite automaton) can be simulated by a (2n+2)-state quasi-sweeping 2nfa. Such a result, besides providing a new "normal form" for two-way nondeterministic finite automata, enables to obtain a subexponential simulation of unary 2nfa's by 2dfa's (two-way deterministic finite automata). It was proved that any n-state unary 2nfa can be simulated by a sweeping 2dfa with O(n^{log_2(n+1)+3}) states (Geffert et al., VEGA 1/7465/20). New necessary and/or sufficient conditions for equality of certain classes of thin sets defined by various functions were found. The most important result is the obtaining the lower estimates for cardinalities of bases for certain classes of thin sets. These results were not known even for the classic trigonometric case (Bukovský et al., VEGA 12/7555/20). The relationships among classes of topological spaces connected with the so-called Hurewicz property was found. It was possible to obtain a complete overview of equalities and inequalities among these classes. The most important result is the identification of the class of so-called mQN spaces and spaces with countable Hurewicz property which provides solutions to a number of open problems (NATO PST.CLG.977652). Hypermedia presentation entitled „Preparation of primary and secondary school teachers for independent creation of hypermedia teaching material“, Part II was prepared. The volume is divided into two parts: the first comprises text of lectures while the second consists of presentations of specific hypermedia projects (Andrejková, KEGA 255/2000).

1. Bukovský L., Reclaw I., Repický M.: Spaces not distinguishing convergences of real – valued functions. Topol. Appl. 112, 13-40, 2001. Int. J. Game Theory 29, 487-494, 2001. 2. Vojtáš P.: Fuzzy logic programming. Fuzzy Set. Syst. 124, 361-370, 2001. 3. Geffert V., Mereghetti C., Pighizzini G.: Converting two-way nondeterministic unary automata into simpler automata. Theor. Comput. Sci. (to appear), 19 pp., 2002.

34 MATHEMATICS

Department of Geometry and Algebra

Mailing address: Department of Geometry and Algebra Faculty of Science P. J. Šafárik University Jesenná 5 04154 Košice

Head of Department: Prof. Stanislav Jendroľ, DSc.

Full-Time Professor: Stanislav Jendroľ, DSc.

Full-Time Assoc. Professors: Katarína Cechlárová, PhD. Mirko Horňák, PhD. Matúš Harminc, PhD. Jaroslav Ivančo, PhD. Judita Lihová, PhD. Danica Studenovská, PhD. Marián Trenkler, PhD.

35 Part-Time Assoc. Professor: Peter Mihók, PhD. Marián Klešč, PhD. Miroslav Ploštica, PhD.

Assist. Professors: Gabriel Semanišin, PhD. Roman Soták, PhD. Tomáš Madaras

Doctoral Students: Erik Bruoth Stanislav Dubrovčák Jana Hajduková Vladimír Lacko Andrea Marcinová Gabriela Martinove Karla Musilová Danka Timková

Home Collaboration : Departments of Mathematics at: Matej Bel University, Banská Bystrica, Faculty of Mathematics and Physics, Comenius University, Bratislava, Slovak Technical University, Bratislava, Technical University, Košice, University of Transport and Communication, Žilina Institute of Mathematics, Slovak Academy of Sciences, Bratislava

Foreign Partners : Departments of Mathematics at: Technical University Klagenfurt, Technical University Wien, Austria, Charles University, Prague, Masaryk University, Brno, Palacký University, Olomouc, West Bohemian University, Plzeň, Czech Republic, Technical University Ilmenau, Technical University Dresden, Technical University Braunschweig, Technical University Freiberg, Germany, Mathematical Institute, Hungarian Academy of Sciences, Budapest, SZTAKI Budapest, Technical University Budapest, Hungary, Keio University, Yokohama, Japan, AGH Krakow, Technical University, Warsaw, Technical University, Zielona Góra, Poland, University of Ljubljana, Slovenia, University of Surrey, Guildford, UK, University of Louisville, Louisville, Vanderbilt University, Nashville, University of Washington, Seattle, USA.

Department of Mathematical Analysis

Mailing address: Department of Mathematical Analysis Faculty of Science P. J. Šafárik University Jesenná 5 04154 Košice

36 Telephone: +421-55-6222932, 6221926, 6221128, 6222971 Fax: +421-55-6222124 E-mail: [email protected]

Head of Department: Assoc. Prof. Jozef Džurina, PhD.

Full-Time Assoc. Professors: Zuzana Bukovská, PhD. Jozef Džurina, PhD. Božena Miháliková, PhD. Ján Ohriska, PhD. Dušan Šveda, PhD.

Part-Time Assoc. Professor: Ján Borsík, PhD. Cyril Lenárt, PhD.

Assist. Professors: Štefan Kulcsár, PhD. Oľga Kulcsárová, PhD. Valéria Skřivánková, PhD. Ivan Žežula,PhD. Martina Hančová Denisa Kaňuková Stanislav Lukáč Ingrid Semanišinová Zuzana Slováková Ľubomír Šnajder

Doctoral Students: Ingrid Minďaková Alena Šimčová Silvia Švihlová

Home Collaboration : Faculty of Science, University of Žilina, Žilina

Foreign Partners : Department of Mathematics, Masaryk University, Brno, Czech Republic Department of Mathematics, University of Ioannina, Ioannina, Greece Institute of Mathematics and Informatics, Lajos Kossuth University, Debrecen, Hungary Department of Mathematics and Computing, University of Veszprém, Hungary Laboratory for Computer Technique and Automatisation, Joint Institute for Nuclear Research, Dubna, Russia

Research Projects

Asymptotic properties of functional differential equations. VEGA 1/7466/20 (Jozef Džurina, 1/2000 - 12/2002)

Polyhedra, graphs and their properties. VEGA 1/7467/20 (Stanislav Jendroľ, 1/2000 - 12/2002)

37 Algebraic structures. VEGA 1/7468/20 (Danica Studenovská, 1/2000 - 12/2002)

Hypermedia and the Internet in training mathematics and computer science teachers. VEGA 1/7472/20 (Dušan Šveda, 1/2000 - 12/2002)

Extended growth curve model and its applications. VEGA 1/7471/20 (Ivan Žežula, 1/2000 - 12/2002)

Selected Results

The exact solution concerning the cyclic chromatic number, problem of convex 3-polytopes has been obtained for all convex 3-polytopes having k-gonal faces, k  60, (Enomoto et al., J. Discrete Math.). Unexpected result has been found saying that the weight of any induced path and an induced cycle in claw-free graphs is independent from the length of the path or the cycle, respectively (Harant et al., J. Graph Theory). An old problem concerning the edge weights in simple graph posed by the famous Hungarian mathematician P. Erdős was solved completely (Jendroľ, Schiermeyer, Combinatorica). New original knowledge about the structure of light subgraphs in different families of maps on compact 2-manifolds were added to the topological graph theory (Jendroľ, Voss, Discrete Math. vol. 233, Discrete Math. vol. 236, Ann. Combinatorics). The complete characterisation of all non planar graphs whose line graph have crossing number one is given. This result corrects a blunder published in a paper which appeared in J. Graph Theory in 1979 (Jendroľ, Klešč, J. Graph Theory). A positive answer regarding an existence of (so called) I(5,n)-fulleroids, another candidates for carbon molecules, was given. The geometric structure of I(5,n)-fulleroids is very similar to that of the famous fullerenes. Thus, the questions postulated by English theoretical chemist P. Fowler, a French geometer Deza and a German informatician Delgado were answered (Jendroľ, Trenkler, J. Math. Chem.). In the oscillation theory of ordinary differential equations, new comparison principles and their application to problems discussed in the theory of FDEs with or without the neutral terms were established and conditions for all non-oscillatory solutions with certain asymptotic behaviour were obtained. Moreover, oscillatory and asymptotic properties of solutions of ordinary differential equations, especially with quasi-derivatives (linear, non-linear, with damping, with deviating arguments), were discussed and the qualitative properties of the neutral and FDEs of the second order and two-dimensional systems of neutral differential equations were dealt with (Džurina, Math Slovaca; Džurina, Kulcsár, Publ. Math. Debrecen, VEGA 1/7466/20). A new discrete model of mathematical economy to study countries formation was proposed and showed that results implied by continuous models (Alesina and Spolaore: Democratisation leads to splitting of countries) are not valid in general (Cechlárová et al., J. Global Optim.). An algorithm for finding the maximum cardinality matroid intersection was extended to enable it also to partition the elements of the basic set to three classes; elements belonging to all optimum solutions, elements belonging to none and elements belonging to some but not to all optimum solutions (Cechlárová, Lacko, Discrete Appl. Math.) The extended growth curve model with variance components were studied. An iterative procedure for the estimation of the first order parameters in the model with unknown second order parameters was developed. (Baranová et al., Folia Vet., VEGA 1/7471/20) The definitive answer to the question of the existence of magic cubes in higher dimensions is given (Mihalíková, Study Univ. Žilina). Discrete model of dynamic portfolio of financial assets was constructed (Skřivánková, Hančová, Matem., fyz., inform.). Objective measures of portfolio risk, financial time series analysis and forecasting were discussed (Skřivánková, Skřivánek, STATIS

38 Bratislava). Probability of ruin and optimal investment strategies were found (Skřivánková, Hančová, Matem. fyz. inform.) The role of mathematical contents, teaching methods and information technologies to achieve principal goals of mathematical education were discussed (Cechlárová et al, Textbook, PF UPJŠ Košice, Harminc, Semanišinová, Acta Univ. Purkyn., Lukáč, Textbook, PF UPJŠ Košice, Lukáč, Šnajder, Textbook, Slov. Pedag. Publish. House, Moravčíkova et al, Int. J. Cont. Eng. Educ. Life- long Learn., Šnajder et al., Textbook, PF UPJŠ Košice, Šveda, Minďáková, Proc. Int. Conf., PF UPJŠ Košice). Selected publications

1. Baranová M., Maľa P., Burdová D., Jacková A., Žežula I.: The influence of the nitrate load on the accumulation of nitrates and nitrites in slaughter poultry. Folia Vet. 45, 157-159, 2001 2. Cechlárová K., Dahm M., Lacko V.: Efficiency and stability in a discrete model of country formation. J. Global Optim. 20, 239-256, 2001 3. Cechlárová K., Lacko V.: Persistency in combinatorial optimisation problems on matroids. Discrete Appl. Math. 110, 121-132, 2001 4. Cechlárová K., Romero-Medina A.: Stability in coalition formation games. Int. J. Game Theory 29, 487-494, 2001 5. Cechlárová K., Semanišinová I., Šveda D.: Mathematics of everyday life. Textbook, PF UPJŠ Košice, 2001, 45 pp. 6. Džurina J.: Unbounded oscillation of the second order neutral differential equations. Math. Slovaca, 51, 441-447, 2001 7. Džurina J., Kulcsár Š.: Oscillation criteria for second order neutral functional differential equations. Publ. Math. Debrecen 1-2, 59, 25-33, 2001 8. Enomoto H., Horňák M., Jendroľ S.: Cyclic chromatic number of 3-connected plane graphs SIAM. J. Discrete Math. 14, 121-137, 2001 9. Harant J., Horňák M., Skupień Z.: Separating 3-cycles in plane triangulations. Discrete Math. 239, 127-136, 2001 10. Harant J., Jendroľ S., Randerath B., Ryjáček Z., Schiermeyer I., Voigt M.:

On weights of induced paths and cycles in claw free and K1,r-free graphs. J. Graph Theory, 131-143, 2001 11. Harminc, M.: Activities with domino in elementarily mathematics. Orava J., 2, 16-17, 2001 12. Harminc M., Semanišinová I.: The Rareer Method of Repetition. Acta Univ. Purkyn. 72, 103-108, 2001 13. Harminc M., Soták R.: Graphs with average labelling. Discrete Math. 233, 127-132, 2001 14. Horňák M., Pčola Š.:

Achromatic number of K5 × Kn for large n. Discrete Math. 234, 159-169, 2001 15. Jendroľ S., Klešč M.: On graphs whose line graphs have crossing number one. J. Graph Theory 37, 181-188, 2001 16. Jendroľ S., Owens P. J.: On light graphs in 3-connected plane graphs without triangular or quadrangular faces. Graph. Combinator. 17, 659-680, 2001

39 17. Jendroľ S., Schiermeyer I. On a max-min problem concerning weights of edges. Combinatorica 21(3), 351-359, 2001 18. Jendroľ S., Trenkler M.: More icosahedral fulleroids. J. Math. Chem. 29, 235-243, 2001 19. Jendroľ S., Voss H.-J.: Light subgraphs of multigraphs on compact 2-dimensional manifolds. Discrete Math. 233, 329-351, 2001 20. Jendroľ S., Voss H.-J.: Local structures in plane maps and distance colourings. Discrete Math. 236, 167-177, 2001 21. Jendroľ S., Voss H.-J.: Subgraphs with restricted degrees of their vertices in polyhedral maps on compact 2-manifolds. Ann. Combinatorics 5, 211-226, 2001 22. Lihová J.: Strict order-betweennesses. Acta Univ. M. Belii, Math. 27-33, 2001 23. Lukáč S.: Multimedia and computer assisted learning of mathematics. Textbook, PF UPJŠ Košice, 2001, 60 pp. 24. Lukáč S., Semanišinová I., Šnajder Ľ.: Computer aided mathematical teaching. Textbook, PF UPJŠ Košice, 2001, 56 pp. 25. Lukáč S., Šnajder Ľ.: Thematic exercise book „ Working with tables“ for 1st class of grammar school. Textbook, Slov. Pedag. Publish. House, Bratislava, 2001, 48 pp. 26. Mihalíková B.: A note on the asymptotic properties of systems of neutral differential equations. Stud. Univ. Žilina, 13, 133-139, 2001 27. Moravčíková Ľ., Kalas I., Šnajder Ľ.: Integration of ICT into education in Slovak republic. Int. J. Cont. Eng. Educ. Life-long Learn., 11, 468-486, 2001 28. Skřivánková V., Hančová M.: Win or bankruptcy? Matem., fyz., inform. 5, 269-276, 2000-2001 29. Skřivánková V., Skřivánek J.: Quantitative methods in finance. Textbook, STATIS Bratislava, 2001, 124 pp. 30. Šnajder Ľ. a kol.: Education teleprojects. Textbook, PF UPJŠ Košice, 2001, 69 pp. 31. Šnajder Ľ., Lukáč S., Šimčová A.: Introduction to working with computers. PF UPJŠ - textbook, 2001, 54 pp. 32. Šveda D., Minďáková I.: Collection of mathematical exercises as a database Proc. Int. Conf. „Scheme of Further Education of Natural Science Teachers“, PF UPJŠ Košice, 128-131, 2001 33. Trenkler M.: Magic p-dimensional cubes. Acta Arith. 96, 361-364, 2001 34. Trenkler M.: Super-magic complete n-partite hypergraphs. Graph. Combinatorics 17, 171-175, 2001

40 PHYSICS

Department of Biophysics

Mailing address: Department of Biophysics Faculty of Science P. J. Šafárik University Jesenná 5 04154 Košice

Head of Department: Prof. Pavol Miškovský, DSc.

Full-time Professor: Pavol Miškovský, DSc.

Full-time Assoc. Professors: Pavol Jasem, PhD. Vladimír Lisý, PhD.

Assist. Professor: Jozef Uličný, PhD.

Senior Researcher: Branislav Brutovský, PhD.

41 Doctoral Students: Jozef Hritz Silvia Kočanová Andrea Petrufová Mária Richterová

Home Collaboration : Institute of Drugs Research, Modra Department of Biophysics and Chemical Physics, Comenius University, Bratislava International Laser Centre, Bratislava

Foreign Partners : Institute of Physics, Charles University, Prague, Czech Republic Laboratory of Physics and Chemistry of Biomolecules, University P. and M. Curie, Paris, France Department of Biochemistry, University of Bologna, Italy Materials Science Institute of Madrid, CSIC, Madrid, Spain Department of Physical Chemistry, Arrhenius Laboratory, University of Stockholm, Sweden Department of Theoretical Physics, Odessa State University, Ukraine Department of Chemistry, Iowa State University, Ames, USA

Department of Experimental Physics

Mailing address: Department of Experimental Physics Faculty of Science P. J. Šafárik University Park Angelinum 9 04154 Košice

Head of Department: Assoc. Prof. Peter Kollár, PhD.

Full-time Professor: Alexander Feher, DSc.

Visiting Professor: Olexander Anders, DSc.

Full-time Assoc. Professors: Josef Gajdušek, PhD. Peter Kollár, PhD. Michal Konč, PhD. Martin Orendáč, PhD. Pavol Petrovič, PhD. Pavol Sovák, PhD. Pavol Vojtaník, DSc.

Assist. Professors: Ján Degro, PhD.

42 Zuzana Ješková, PhD. Marián Kireš, PhD. Peter Matta, PhD. Ľudmila Onderová, PhD. Tibor Švec, PhD.

Senior Researchers: Erik Čižmár, PhD. Ján Füzer, PhD. Róbert Harakály, PhD. Ľuboš Lokner, PhD. Alžbeta Orendáčová, PhD. Rastislav Varga, PhD. Zuzana Zorkovská, PhD.

Researchers : Jaroslav Chovan Peter Marko Radomír Mlýnek Adriana Zeleňáková

Doctoral Students: Rastislav Andrejco Jozef Bednarčík Erika Fechová Vladimír Grejták Marcela Kajňáková Radoslav Kalakay Tibor Révay Adriana Trojanovičová Alexander Vlček

Home Collaboration : Institute of Experimental Physics, Slovak Academy of Sciences, Košice US Steel, Steel Co.Ltd., Košice

Foreign Partners : Institute of Experimental Physics, Vienna University of Technology, Vienna, Austria Very Low Temperature Research Centre, National Centre for Scientific Research, Grenoble, France Institute of Physics, University of Bayreuth, Germany IWW, Technical University Clausthal, Clausthal-Zellerfeld, Germany Department of Physics, University of Crete, Heraklion, Greece Central Research Institute for Physics, Hungarian Academy of Science, Budapest, Hungary Faculty of Physics, Adam Mickiewicz University, Poznan, Poland Department of Physics, Faculty of Teaching, C. Pulaski Technical University, Radom, Poland Department of Solid State Physics, University of Lodž, Lodž, Poland Institute of Molecular Physics, Polish Academy of Science, Poznan, Poland Institute of Physics, Polish Academy of Science, Warsaw, Poland P. L. Kapica Institute for Physical Problems, Russian Academy of Sciences, Moscow, Russia Department of Physics, Uzhgorod State University, Uzhgorod, Ukraine Institute for Low Temperature Physics, UAS, Kharkov, Ukraine Department of Physics, University of Florida, Gainesville, USA

43 Department of Nuclear Physics

Mailing address: Department of Nuclear Physics Faculty of Science P. J. Šafárik University Jesenná 5 04154 Košice

Telephone: + 421-55-6221926, 6221128, 6222971, 6258683 Fax: + 421-55-6222124 E-mail: [email protected]

Head of Department: Prof. Gabriela Martinská, PhD.

Full-time Professor: Gabriela Martinská, PhD.

Part-time Professor: Emanuel Síleš, PhD.

Full-time Assoc. Professor: Stanislav Vokál, PhD.

Assist. Professors: Adela Kravčáková, PhD. Jana Vrláková

Senior Researchers: Alexander Dirner, PhD. Jozef Urbán, PhD.

Researchers: Ján Fedorišin Ján Mušinský Ján Solár Marcel Uličný Martina Vytykačová

Doctoral Students: Radovan Brenkus Filip Tomasz

Home Collaboration: Institute of Experimental Physics, Slovak Academy of Sciences, Košice

Foreign Partners: Yerevan Physics Institute, Yerevan, Armenia School of Physics, University of Sydney, Sydney, Australia Institute of High Energy Physics, Academia Sinica, Beijing, China Institute of Particle Physics, Hua-Zhong University, Wuhan, Hubei, China Department of Physics, Hunan Education Institute, Changsha, Hunan, China Department of Physics, Shanxi Normal University, Linfen, Shanxi, China Cairo University, Cairo, Egypt Institute of Nuclear Physics, Research Centre Jülich, Germany Department of Physics, Panjab University, Chandigarh, India Department of Physics, University of Rajastan, Jaipur, India

44 Department of Physics, University of Jammu, Jammu, India Banaras Hindu University, Varanasi, India High Energy Physics Institute, Alma-Ata, Kazakhstan Institute of Atomic Energy, Warsaw, Poland Institute of Gravitation and Space Research, Bucharest, Romania Laboratory High Energy Physics, Joint Institute for Nuclear Research, Dubna, Russia P. N. Lebedev Institute of Physics, Moscow, Russia V. G. Khlopin Radium Institute, St. Petersburg, Russia Polytechnic Institute, St. Petersburg, Russia Department of Physics, University of Lund, Lund, Sweden European Organization for Nuclear Research (CERN), Geneva, Switzerland Laboratory of Relativistic Nuclear Physics, Institute of Nuclear Physics, Tashkent, Uzbekistan Laboratory of High Energies, Physical-Technical Institute, Tashkent, Uzbekistan

Department of Theoretical Physics and Geophysics

Mailing address: Department of Theoretical Physics and Geophysics Faculty of Science P. J. Šafárik University Moyzesova 16 04154 Košice

Telephone: +421-55-6225358, 6222121-3 Fax: +421-55-6222124 E-mail: [email protected]

Head of Department: Prof. Andrej Bobák, DSc.

Full-time Professors: Andrej Bobák, DSc. Slavko Chalupka, PhD.

Full-time Assoc. Professors: Vladimír Ilkovič, PhD. Michal Jaščur, PhD. Ľubomír Tóth, PhD. Eva Vargová, PhD. Angela Zentková, PhD.

Assist. Professors: Denis Horváth, PhD. Samuel Mockovčiak, PhD.

Senior Researcher: Rudolf Gális, PhD.

45 Researcher: Štefan Parimucha

Doctoral Students: Fathi O. A. Abubrig Silvia Lacková Jozef Strečka Martin Gmitra

Home Collaboration : Institute of Experimental Physics, Slovak Academy of Sciences, Košice Astronomical Institute, Slovak Academy of Sciences, Tatranská Lomnica

Foreign Partners : Astronomical Institute, Academy of Sciences of the Czech Republic, Ondřejov, Czech Republic Institute of Astrophysics, Paris, France Gerhard Mercator University, Duisburg, Germany University of Athens, Greece Department of Physics, University of Naples „Federico II”, Naples, Italy Department of Applied Science, Kyushu University, Fukuoka, Japan Department of Informatics, Nagoya University, Nagoya, Japan Department of Solid State Physics, University of Lodž, Lodž, Poland Joint Institute of Nuclear Research, Dubna, Russia Uzhgorod State University, Uzhgorod, Ukraine

Research Projects

A theoretical study of the mixed-spin magnetic systems. VEGA 1/6020/99 (Andrej Bobák, 1/1999 – 12/2001)

Magnetic quantum states of one-dimensional magnetics and superfluid helium 3He-B at very low temperatures. VEGA 1/7473/20 (Alexander Feher, 1/2000 - 12/2002)

Magnetic properties of crystalline and amorphous thin films with layer structure. VEGA 1/6021/99 (Vladimír Ilkovič, 1/1999 - 12/2001)

The structure and magnetic properties of amorphous and fine grain ferromagnets. VEGA 1/8040/01 (Peter Kollár, 1/2001 - 12/2003)

The influence of segregation and precipitation processes on quality of intercrystalline interface in alloyed steel for energy industry. VEGA 2/1062/21 (Jana Kresťanková, 1/2001 – 12/2003)

Dynamics of biological macromolecules and vesicles: collective excitations, surface phenomena and their effects in spectroscopic experiments. VEGA 1/7401/20 (Vladimír Lisý, 1/2000 - 12/2002)

Excitations in superfluid phases of helium-3 at ultralow temperatures. VEGA 2/7226/20 (Ľuboš Lokner, 1/2000 - 12/2002)

Near threshold meson production, correlations and spin effects in light nuclei reactions. VEGA 1/8041/01 (Gabriela Martinská, 1/2001 - 12/2003)

Study of electron-proton interactions in H1 experiment in conditions of extended illumination. VEGA 2/1169/21 (Pavol Murín, 1/2001 – 12/2003)

46 Multifrequency analysis of stars in interaction. VEGA 2/1157/21 (Štefan Parimucha, 1/2001 – 12/2003)

Development of new ferromagnetic thin films on Fe and Co basis with nanocrystalline and granular structure. Study of their structure and dynamic and static magnetic properties. VEGA 1/7556/20 (Pavol Sovák, 1/2000 - 12/2002)

Construction and study of potential energy surfaces of selected biologically relevant molecules and their alternative representations by massively parallelizable genetic algorithm, artificial intelligence and neural network techniques. VEGA 1/8045/01 (Marcel Uličný, 1/2001 – 12/203

Study of new forms and phase transitions of nucleic matter at extremal densities of energy. VEGA 1/6112/99 (Jozef Urbán, 1/1999 - 12/2001)

Mathematical methods in gravimetry and magnetometry. VEGA 1/6023/99 (Eva Vargová, 1/1999 - 12/2001)

Relativistic nuclear interactions measured by uniform method in emulsion tracking detector (EMU01 experiments). VEGA 1/6022/99 (Stanislav Vokál, 1/1999 - 12/2001)

Processing and stability of thermodynamically non-equilibrium soft magnetic materials. VEGA 1/8046/01 (Pavol Vojtaník, 1/2001 - 12/2003)

Virtual collaboration - a pilot project. KEGA 253/2000 (Pavol Murín, 1/2000 - 12/2002)

Phase transitions in complex fluids. Slovak-Norwegian project. (Jozef Černák, 1/2000 - 12/2002)

Relativistic analysis of constituent quark model for mesons. Slovak-Ukrainian project. (Slavko Chalupka, 1/2001 – 12/2003)

Characterization of novel low dimensional magnetic systems. NSF INT/2001-0089140. (Alexander Feher, 2/2001 - 1/2004)

Proton transfer in biomolecules: Interaction of hypericin with model cellular components. NSF 9613962 (Pavol Miškovský, 1/1998 - 12/2000)

Antiviral and antineoplastic photo-activity of hypericin and hypocrellin: Mechanism of action on cellular and molecular level. Slovak-French project. (Pavol Miškovský, 1/2001 - 12/2004)

Study of anticancer and antiretroviral activity of aromatic polycyclic dions (hypericin, hypocrellin). Slovak-Czech project. (Pavol Miškovský, 1/2000 - 12/2001) Development of a drug with the active substance Vermikulin and the application of curing herbs, Part. problem: Pharmacological utilisation of hypericin and its derivatives and complexes in photodynamic therapy of AIDS and cancer. R&D project 98-513-I-03 (Pavol Miškovský, 1/1999 - 12/2001)

Selected results In biophysical research, structural and dynamical parameters of the complexes of human serum albumin (HSA) with hypericin (Hyp) and hypocrellin A (HA) have been determined. A detailed structural model of HSA/Hyp has been constructed in which the position of Hyp in the subdomain IIA is defined with respect to the aminoacids near tryptophan 214 (Miškovský et al., Photochem. Photobiol., VEGA 1/6027/99).

47 The theory of the neutron and light scattering by droplet microemulsions has been developed. We described the neutron spin-echo experiments on emulsion systems based on our hypothesis of energy dissipation in the oil-water interface layer (Lisý et al., J. Mol. Liq., VEGA 1/7401/20). The theory of the gamma rays absorption and scattering by hydrated proteins within a Debye- Brinkman model of protein as a porous particle is presented (Tchesskaya, Lisý, J. Mol. Liq., VEGA 1/7401/20). Explanation of the details of excited states and contribution to the mechanism of photoinduced changes of natural photoprotective and immunosuppressive human skin component – urocanic acid by a new theoretical method was made. The method itself is very promising due to low computational cost and high predictive power (Danielsson, et al., J. Amer. Chem. Soc., VEGA 1/8045/01). In the condensed matter physics, experimental studies of two-dimensional 3He at very low temperatures have been carried out. It was demonstrated that in the spin-liquid regime spin frustration appears in the studied system (Collin et al., Phys. Rev. Lett., VEGA 1/7473/20).

The magnetic phase diagram of the dipolar magnetic system KEr(MoO4)2 with strong tetragonal distortion was investigated. The analysis of the experimental results indicates that the dipolar magnet with strong tetragonal distortion in external magnetic field applied along the easy axis resembles the behaviour of the S=1/2 two-dimensional Ising model on the rectangular lattice in B||z with the nearest neighbour interactions only. The behaviour of experimental and numerical data at lower critical temperatures suggests the existence of a tricritical point characteristic for metamagnets (Orendáčová et al., Phys. Rev. B, VEGA 1/7473/20).

The Fe40Ni38Mo4B18 alloy shows structural magnetic relaxation in the temperature range 20- 300 oC. The analysis of the MAE spectrum gives the activation energy spectrum with the pre- -16 exponential factor 0=5x10 s and the most probable activation energy Q = 1.45 eV. Annealing at 400 oC for 1 hour leads to the precipitation of the nanocrystalline fcc-FeNi grains dispersed in the amorphous residual matrix, while annealing at 600 oC/1h results in a two-phase polycrystalline alloy with fcc-FeNi and (FeNiMo)23B6 crystals (Vojtaník et al., Mater. Sci. Forum, VEGA 1/8046/01). The influence of the holes arranged into the lines perpendicular to the ribbon axis produced by laser treating on the domain structure, coercivity, shape and tilting of the hysteresis loops of Finemet was investigated. Small (and optimum) density of dotted lines causes a formation of small domains as a consequence of domain branching. These domains are responsible for the reduction of power losses at higher frequencies (Zeleňáková et al., J. Magn. Magn. Mater., accepted, Zeleňáková et al., Czech J. Phys., accepted, VEGA 1/8040/01). The influence of Al and the selected rare-earth elements (Pr, Nd and Gd) on the structure and magnetic properties of Finemet-type alloys in the form of ribbons and thin films was investigated. Structural investigations, measurements of thermal dependence of magnetization and spin-wave analysis have shown that the small concentration of Al (up to 3 at.%) modifies the short-range order in the alloy in the way that leads to stronger exchange interaction between the Fe atoms (Zorkovská et al., Czech. J. Phys., accepted, VEGA 1/7556/20). Research in nuclear physics was orientated towards the nuclear collision studies in a wide range of relativistic energies (1 A GeV - 200 A GeV) and a large variety of nuclei (d - Pb). Experiments WA97 and NA57 at CERN were designed to study the production of strange and multistrange particles in Pb-Pb and p-Be collisions. The yields and transverse mass spectra of the 0 particles/antiparticles K s, Ξ, Λ, Ω and negative particles were measured in Pb-Pb collisions. A significant strangeness enhancement in central Pb-Pb interaction has been observed in agreement

48 with the hypothesis regarding the quark-gluon plasma (QGP) formation (Antinori, ..., Urbán et al., J. Phys. G.: Nucl. Par. Phys; Nucl. Phys. A, VEGA 2/6113/99). The strange baryon production in the least central Pb-Pb collisions at 158 A GeV/c accessible by NA57 experiment exhibit different behaviour from the more central events, which may indicate an onset of a new regime in nuclear collisions. First results for antibaryon/baryon ratios at 40 A GeV/c were obtained. The combined results of strange baryon production at different energies allow to shed a new light on the creation of the QGP in nuclear collisions (Antinori, ..., Fedorišin at al., Nucl. Phys. A; J. Phys. G.: Nucl. Part. Phys. VEGA 1/6112/99). The 3Hep interactions at 8.0 GeV/c have been studied and the mean free path about 14 000 Z=2 nuclei leading to 2319 secondary interactions was done. An admixture of 0.5% of anomalons was found with a mean free path of 1.5 cm as compared to around 250 cm for primary interactions (Glagolev, …, Martinská et al., Jadernaja fizika, VEGA 1/8041/01). Scaled factorial moment analysis for the multiplicity distributions of shower particles in the pseudorapidity phase space has been done. An evidence for the presence of dynamical fluctuations was shown for the non-peripheral interactions of 28Si+Ag(Br) at 14.6 A GeV/c and 4.5 A GeV/c (Adamovich, …, Kravčáková et al., APH N.S. Heavy Ion Physics, VEGA 1/6022/99). Within the theoretical physics, the global phase diagram of the mixed spin-1 and spin-3/2 Ising ferrimagnetic system with different single-ion anisotropies acting on the spin-1 and spin-3/2 was determined. For the first time, the first-order boundaries separating different ordered phases at low temperatures have been obtained (Abubrig et al., Physica A, VEGA 1/6020/99).

The generalized version of the two sublattice Wu model with two- and four spin interactions was exactly solved by the use of a generalized „star-triangle“ transformation. The existence of a new disordered phase has been predicted in the system with integer spins on one sublattice (Lacková, Jaščur, Phys. Rev. E, VEGA 1/6020/99). Based on the reaction field approximation, the critical behaviour of an amorphous magnetic superlattice consisting of two different ferromagnets was examined for different lattice types and faces (Tuleja et al., phys. stat. sol. (b), VEGA 1/6021/99). In a geophysical research, the mathematical method based on spherical harmonics and Debye potentials have been developed to show the properties of the inverse problem of magnetometry (Chalupka, Vargová, Studia geophys. et geod., VEGA 1/6023/99). The research in astrophysics was directed to the analysis of the light curves of the contact system XY UMa obtained during observing period in 1994-2001 in BVRI filtres (Pribulla et al., Astron. Astrophys., VEGA 2/1157/21). An analysis of UBV photoelectric photometry for the eclipsing binary KW Persei based on new observational data showed that the light changes are not only due to eclipses, but also to activity in the system (Gális et al., Astron. Astrophys.,VEGA 2/1008/21). In a didactics of physics, a new model of teachers´ further education based on a School Information Service was created and tested. (Tempus AC JEP 14327/1999). Selected publications

1. Abubrig O.F., Horváth D., Bobák A., Jaščur M.: Mean-field solution of the mixed spin-1 and spin-3/2 Ising system with different single-ion anisotropy..., Physica A 296, 437-450, 2001 2. Adamovich M.I., ..., Kravčáková A., Vokál S., Vrláková J. et al.: Factorial Moments of 28Si Induced Interactions with Ag(Br) Nuclei, APH N.S. Heavy Ion Phys. 13, 213-221, 2001

49 3. Adloff C., ..., Murín P. et al.: Photoproduction with a leading proton at HERA. Nucl. Phys. B 619, 3-21, 2001 4. Adloff C.,..., Murín P. et al.: A search for leptoquark bosons in e-p collisions at HERA. Phys. Lett. B 523, 234-242, 2001 5. Adloff C.,..., Murín P. et al.: D*+meson production in deep inelastic diffractive interactions at HERA. Phys. Lett. B 520, 191-203, 2001 6. Adloff C.,..., Murín P. et al.: Deep inelastic inclusive e+p scattering at low x and a determination of alpha(s). Eur. Phys. J. C21, 33-61, 2001 7. Adloff C.,..., Murín P. et al.: Diffractive jet production in deep inelastic e+p collisions at HERA. Eur. Phys. J. C20, 29-49, 2001 8. Adloff C.,..., Murín P. et al.: Dijet production in charged and neutral current e+p interactions at high Q **2. Eur. Phys. J. C19, 429-440, 2001 9. Adloff C.,..., Murín P. et al.: Measurement and QCD analysis of jet cross-sections in deep inelastic positron-proton collisions at s**(1/2) of 300 GeV. Eur. Phys. J. C19, 289-311, 2001 10. Adloff C.,..., Murín P. et al.: Measurement of deeply virtual Compton scattering at HERA. Phys. Lett. B 517, 47-58, 2001 11. Adloff C.,..., Murín P. et al.: Measurement of neutral and charged current cross-sections in electron-proton collisions at high Q **2. Eur. Phys. J. C19, 269-288, 2001 12. Adloff C.,..., Murín P. et al.: On the rise of the proton structure function F(2) towards low x. Phys. Lett. B 520, 183-190, 2001 13. Adloff C.,..., Murín P. et al.: Searches at HERA for squarks in R-parity violating supersymmetry. Eur. Phys. J. C20, 639-657, 2001 14. Adloff C.,..., Murín P. et al.: Three jet production in deep inelastic scattering at HERA. Phys. Lett. B 515, 17-29, 2001 15. Antinori F., ..., Fedorišin J, Martinská G., Urbán J., Vrláková J. et al.: Status of the NA57 experiment at CERN SPS. J. Phys. G.: Nucl. Part. Phys. 27, 383-390, 2001 16. Antinori F., ..., Fedorišin J, Martinská G., Urbán J., Vrláková J. et al.: Determination of the event centrality in the WA97 and NA57 experiments. J. Phys. G.: Nucl. Part. Phys. 27, 391-396, 2001 17. Antinori F., ..., Fedorišin J, Martinská G., Urbán J., Vrláková J. et al.: Study of the Production of Strange and Multi-Strange Particles in Lead-Lead Interactions at the CERN SPS: the NA57 Experiment. Nucl. Phys. A 681, 165-173, 2001 18. Antinori F., ..., Urbán J., et al.: Strange baryon production in Pb-Pb collisions at 158 A GeV/c. J. Phys. G.: Nucl. Part. Phys. 27, 375-381, 2001 19. Antinori F., ..., Urbán J., et al.: Centrality dependence of the expansion dynamics in Pb-Pb collisions at 158 A GeV. J. Phys. G.: Nucl. Part. Phys. 27, 2325-2344, 2001 20. Antinori F., ..., Urbán J., et al.: Multistrange baryon production in heavy ion reactions at the SPS. Nucl. Phys. A 685, 407-413, 2001 21. Antinori F., ..., Urbán J., et al.: Strange particle production in p-Be, p-Pb, Pb-Pb at 158 A GeV/c (WA97 experiment). Nucl. Phys. A 681, 141-148, 2001 22. Atalaj S., Adiguzel H.I., Squire P.T., Sovák P.: Study of nanocrystalline Fe-M-Cu-Nb-Si-B (M = Cr, Co, Ni) ribbons by elastic modulus measurements.

50 Mat. Sci. Eng. A 304-306, 918-922, 2001 23. Chalupka S., Vargová E.: On some aspects on the inversion problem in magnetostatics. Studia Geophys. et Geodet. 45, 168-175, 2001 24. Chovan J., Papanicolaou N.: Weak ferromagnetism in cuprates. Physica B 296, 163-166, 2001 25. Collin E., Triqueneaux S., Harakály R., Roger M., Bauerle C., Bunkov Yu. M., Godfrin H.: Quantum Frustration in the Spin Liquid Phase of Two-Dimensional 3He. Phys. Rev. Lett. 86, 2477-2450, 2001 26. Danielsson J., Uličný J., Laaksonen A: A TD-DFT study of the photochemistry of urocanic acid in biologically relevant ionic, rotameric, and protomeric forms. J. Am. Chem. Soc. 123, 9817-9821, 2001 27. Fechová E., Kováč J., Kollár P., Füzer J., Konč M.: The structure and magnetic properties of powder FINEMET materials. J. Metastab. Nanocryst. Mater. 10, 577-582, 2001 28. Gabáni S., Flachbart K., Konovalova E., Orendáč M., Paderno Y., Pavlík V., Šebek J.:

Properties of the in-gap states in SmB6,. Solid State Commun. 117, 641-644, 2001 29. Gális R., Hric L. Niarchos P.: KW Persei – a near-contact system? Astron. Astrophys. 373, 950-959, 2001 30. Glagolev V.V., ..., Martinská G., Urbán J. et al.: Mean free path of the Z=2 nuclei from 3Hep interactions in liquid hydrogen. Jader. Fiz. 64, 969-974, 2001 31. Horváth D., Gmitra M., Vávra I.: Neural network approach to magnetic dot arrays modelling. J. Magn. Magn. Mater. 231, 273-286, 2001 32. Kollár P., Fechová E., Füzer J., Zeleňáková A., Kavečanský V., Kováč J., Konč M.:

The magnetic properties of compacted Fe73,5Cu1Nb3Si13,5B9 alloy in amorphous and nanocrystalline state. J. Metastab. Nanocryst. Mater. 10, 559-564, 2001 33. Lacková S., Jaščur M.: Exact results of a generalized Wu model with two- and four-spin interactions. Phys. Rev. E 64, 036126-1- 036126-6, 2001 34. Lisý V., Brutovský B., Zatovsky A.V., Zvelindovsky A.V.: On the theory of light and neutron scattering from droplet microemulsions. J. Mol. Liq. 93, 113-118, 2001 35. Miškovský P., Hritz J., Sánchez-Cortés S., Fabriciová G., Uličný J., Chinsky L.: Interaction of hypericin with serum albumins: surface enhanced Raman spectroscopy and molecular modelling study. Photochem. Photobiol. 74, 172-183, 2001 36. Orendáčová A., Horváth D., Orendáč M., Čižmár E., Kačmár M., Bondarenko V., Anders A. G., Feher A.: Monte Carlo studies of the magnetic phase diagram of Ker(MoO4)2 : A dipolar magnet with strong tetragonal distortion. Phys. Rev. B 65, 014420-1-014420-8, 2001 37. Pinčák R., Pudlák M.: Noise breaking the twofold symmetry of photosynthetic reaction centers: electron transfer. Phys. Rev. E 64, 031906 1-10, 2001 38. Pribulla T., Chochol D., Heckert P. A., Errico L., Vittone A.A., Parimucha Š., Teodorani, M.: An active binary XY UMa revisited. Astron. Astrophys. 371, 997-1011, 2001 39. Pribulla T., Vaňko M., Chochol D., Parimucha Š.: Photoelectric photometry of the eclipsing contact binaries: EF Dra, GW Cep and CW Cas. Contrib. Astron. Obs. Skalnaté Pleso 31, 26-42, 2001 40. Staničová J., Kovalčík P., Chinsky L., Miškovský P.: Pre-resonance Raman and surface-enhanced Raman spectroscopy study of the complex of the antiviral and antiparkinsonian drug amantadine with histidine. Vib. Spectrosc. 25, 41-51, 2001 41. Tchesskaya T.Yu., Lisý V.: Hydrodynamic fluctuations of liquids inside and out of porous particle.

51 J. Mol. Liq. 93, 123-126, 2001 42. Tuleja S., Ilkovič V., Mockovčiak S., Tóth Ľ.: Critical behaviour in magnetic amorphous superlattice. Phys. stat. sol. (b) 227, 569-577, 2001 43. Vaňko M., Pribulla T., Chochol D.,Parimucha Š., Kim C. H., Lee J. W., Han J. Y.: Photoelectric and CCD photometry of eclipsing contact binaries: UV Lyn, FU Dra and AH Aur. Contrib. Astron. Obs. Skalnaté Pleso 31, 129-147, 2001 44. Varga R., Marko P., Vojtaník P.: Perminvar effect in amorphous FeCrSiB alloys. Mater. Sci. Forum, 373-376, 401-404, 2001 45. Vojtaník P., Matejko R., Varga R., Ocelík V.: Structural and magnetic properties of nanocrystalline FeNiMoB precursor. Mater. Sci. Forum, 373-376, 237-240, 2001 46. Vojtaník P.: Magnetic relaxations and magnetization properties of ferromagnetic alloys. Mater. Sci. Forum, 373-376, 87-92, 2001 47. Zeleňáková A., Kollár P., Vértesy Z., Kuzminski M., Ramin D., Rieheman W: Influence of small circular holes on the coercivity and domain structure of nanocrystalline Finemet. Scripta Mater. 44, 613-617, 2001

SOCIAL SCIENCES

Department of Philosophy, Pedagogy and Psychology

Mailing address: Department of Philosophy, Pedagogy and Psychology Faculty of Science P. J. Šafárik University Mánesova 23 041 67 Košice

Telephone: + 421-95-6322122, 6337352-53, 6331556 Fax: + 421-95-6222124 E-mail: [email protected]

Head of Department: Assoc. Prof. Irena Lokšová, PhD. Full-Time Assoc. Professors: Irena Lokšová, PhD. Eva Schnitzerová, PhD.

Assist. Professors: Peter Nezník, PhD. Oľga Orosová,PhD. Silvia Kontírová Pavol Tholt

Home Collaboration :

52 Faculty of Medicine, P. J. Šafárik University, Košice Foundation FILIA, Košice Matej Bel University, Banská Bystrica Pedagogical and Psychological Departments of Comenius University, Bratislava and Constatine the Philosopher University, Nitra University of Prešov, Prešov

Foreign Partners : Pedagogical and Psychological Departments of Universities in Brno, Ostrava, Prague and Olomouc, Czech Republic University Bayreuth, Germany University Udine, Italy University Opole, Poland Welsh University, Longwood, UK

Selected Results

Textbook devoted to prevention of drug addiction was written in co-operation with the Faculty of Medicine, P. J. Šafárik University, Košice, the Faculty of Philosophy, University of Prešov and the FILIA Foundation, Košice (Orosová, Schnitzerová). The textbook offers basic psychological, philosophical and medical information in the field of drug addiction prevention and prevention of risky behaviour for students. A textbook “Can we understand to children? (Psychological theories help to teachers)”, (Orosová O.), intended to develop the teachers´ ability to be competent in helping, was written. The book has been distributed among all relevant school offices and basic and secondary schools in the Slovak Republic.

1. Lokšová,I.: Conception of creative teaching. Pedagogická orientace p. 6-12., 2001 2. Orosová, O.: Narrative approach to psychological preparation of teachers. Pedagogická revue, 53, 4, p. 320 330, 2001 3. Schnitzerová,E., Orosová,O.: Primary prevention of addictions and preparation of upcoming teachers to its realisation. Technológia vzdelávania, IX, 1, p.14-16, 2001 4. Schnitzerová,E.: Social behaviour of students in context of traditional and alternative education. Technológia vzdelávania, IX, 9, p.14-17, 2001 5. Schnitzerová,E.: Prosocial behaviour and possibilities of its development. Pedagogické spektrum, X, 9/10 , p.25 33, 2001