Supplementary T Able 2. Clinical Data of the Analyzed Samples. Asterisk (*) Indicates Laser

Supplementary Table 2. Clinical data of the analyzed samples. Asterisk (*) indicates laser microdissected samples.

Sample ID Sampl Age range Localization Histology TNM Grade Dukes e type NAT NAT1* fresh 60-91 years sigma NAT frozen tissue NAT2* fresh rectum NAT frozen tissue NAT3* fresh colon NAT frozen descendens tissue NAT4* fresh sigma NAT frozen tissue NAT5* fresh colon ascendens NAT frozen tissue NAT6 fresh rectum NAT frozen tissue NAT7 fresh coecum NAT frozen tissue NAT8 fresh coecum NAT frozen tissue NAT9 fresh sigma NAT frozen tissue NAT10 fresh sigma NAT frozen tissue NAT11 fresh colon ascendens NAT

1 frozen tissue NAT12 fresh colon ascendens NAT frozen tissue NAT13 fresh coecum NAT frozen tissue NAT14 fresh sigma NAT frozen tissue NAT15 fresh colon ascendens NAT frozen tissue Adenoma Ad1* fresh 48-78 years rectum tubular adenoma frozen tissue Ad2* fresh rectum tubular adenoma frozen tissue Ad3* fresh sigma tubular adenoma frozen tissue Ad4* fresh colon tubular adenoma frozen descendens tissue Ad5* fresh colon tubular adenoma frozen descendens tissue Ad6 biopsy sigma tubular adenoma Ad7 biopsy sigma tubular adenoma

Ad8 biopsy coecum tubular adenoma

Ad9 biopsy colon tubular adenoma descendens Ad10 biopsy sigma tubular adenoma

2 Ad11 biopsy flexura hepatica tubulovillous adenoma

Ad12 biopsy coecum tubulovillous adenoma

Ad13 biopsy sigma tubulovillous adenoma

Ad14 biopsy colon tubulovillous adenoma descendens Ad15 biopsy rectum tubulovillous adenoma

CRC CRC1* fresh 60-91 years sigma adenocarcinoma T3N0M0 G2 B frozen tissue CRC2* fresh rectum adenocarcinoma T3N0M0 G2 B frozen tissue CRC3* fresh colon adenocarcinoma T2N0M0 G2 B frozen descendens tissue CRC4* fresh sigma adenocarcinoma T3N0M0 G2 B frozen tissue CRC5* fresh colon ascendens adenocarcinoma T3N0M0 G2 B frozen tissue CRC6 fresh rectum adenocarcinoma T3N2M0 G1 C frozen tissue CRC7 fresh coecum adenocarcinoma T3N0M0 G2 B frozen tissue CRC8 fresh coecum adenocarcinoma T3N0M0 G3 B frozen tissue CRC9 fresh sigma adenocarcinoma T3N1M0 G2 B

3 frozen tissue CRC10 fresh sigma adenocarcinoma T3N2M0 G2 C frozen tissue CRC11 fresh colon ascendens adenocarcinoma T3N2M0 G2 C frozen tissue CRC12 fresh colon ascendens adenocarcinoma T3N2M0 G2 C frozen tissue CRC13 fresh coecum adenocarcinoma T3N2M0 G1 C frozen tissue CRC14 fresh sigma adenocarcinoma T3N0M0 G1 B frozen tissue CRC15 fresh colon ascendens adenocarcinoma T3N1M0 G2 C frozen tissue