Mutation Study Guide for Chapter 12 Sections 4 and 5

1. Make 3 columns, one for Point Mutations, Frameshift mutations & one for Chromosomal Mutations. Place each word or phrase under then correct heading. a) changes that involve a single nucleotide b) inversions c) substitution d) translocation e) insertion f) deletion

2) Differences between Prokaryotes and Eukaryotes. Make 2 columns again and the place the correct phrases under the heading prokaryotes or eukaryotes a) DNA is located in the nucleus b) is circular c) has an operon d) has enhancers and promoter sequences e) hox genes f) TATA box g) promoter h) gene regulation allow for cell specialization i) enhancer sequences

3. Pick all that are true: A Promoter (true or false) a) determines whether a gene is expressed b) is found after a TATA box c) is a binding site for DNA polymerase d) is a binding site for RNA polymerase e) is a DNA sequence f) is a stop or start signal for transcription

4. Pick all statements that are true about Hox Genes (true or false) a) mutations do not occur in hox genes b) they control the normal development of an animal c) occur in clusters d) determines the basic plan

5. Pick all that are true about the Lac operon (true or false) A) controls the breakdown of lactose b) controls the production of lactose c) found in prokaryotes d) found in eukaryotes e) found in bacteria f) are a group of genes that work together g) contains an operator and a promoter h) turns genes off and on as different proteins are needed i) controls the differentiation of cells

6. Lac genes circle the correct answer(s) a) are turned off by repressors b) is turned on by repressor c) turned off by lactose d) turned on by lactose

7. Gene regulation (pick the ones that are true) a) turns off or on as different proteins are needed b) Only a fraction of the available genes need to be expressed in the appropriate cells of different tissues throughout the body c) not all cells in multi cellular organism carry the complete genetic code.