Curriculum Vitae Michael F. O'brien, M.D

CURRICULUM VITAE MICHAEL F. O'BRIEN, M.D.

Office: Miami Children's Hospital 3100 S.W. 62nd Avenue Miami, Florida 33155-3009 Phone: (305) 662-8366 Fax: (305) 663-9194 E-Mail: [email protected]

Date of Birth: June 14, 1954

Place of Birth: Hartford, Connecticut

Education: Medical School: State University of New York at Downstate Brooklyn, New York September 1985 - June 1987 M.D., 1987

Albany Medical College Albany, New York September 1983 - June 1985

College: Columbia University New York, New York September 1979 - May 1983 Bachelor of Science, 1983

University of Montana Missoula, Montana September 1972 - May 1973

Graduate Hospital Clinical Experience: Fellowship Scoliosis Research Society Traveling Fellowship 1997 Ronald L. DeWald, M.D. 1725 W. Harrison St. #440 Chicago, Illinois 60612 May 17, 1997 - June 7, 1997

International Spine Fellowship H Alan Crockard FRCS National Hospital for Neurology and Neurosurgery Queens Square - London, England August 1, 1993 - September 1, 1994

Spine Surgery Fellowship Keith H. Bridwell MD Barnes Hospital Washington University Medical Center St. Louis, Missouri July 1, 1992 - August 1, 1993

Residency: State University of New York at Downstate/ Kings County Hospital Brooklyn, New York Orthopaedic Surgery Resident July 1, 1988 - June 30, 1992

Internship: State University of New York at Downstate/ Kings County Hospital Brooklyn, New York Surgical Intern July 1, 1987 - June 30, 1988

Degrees: Charter Diplomat - American Board of Spine Surgery 1998 Diplomat - American Board of Orthopaedic Surgery 1997 Part I, American Board of Orthopaedic Surgery, 1992 Diplomat - National Board of Medicine Examiners, 1989 Doctor of Medicine, 1987 Bachelor of Science, 1983

Licensure: Colorado - 34814 Florida - ME 0067068 Missouri - MD 100255 New York State - 183459-1 Illinois - 036-102080 Indiana - 01052321 Societies: American Board Spine Surgery North American Spine Society Cervical Spine Research Society Scoliosis Research Society American Academy of Orthopaedic Surgeons American Medical Association Colorado Medical Society Clear Creek Medical Society Denver Medical Society Royal Society of Medicine Florida Medical Association Alachua County Medical Society

Honors: Dean's List Columbia University

National Honor Society Notre Dame High School

Awards: Orthopaedic Research Award SUNY Downstate Medical College June 1987

Fellow Spinal Surgery Paper Award GICD-USA 1994

Scoliosis Research Society Traveling Fellowship Spring 1997

Grants: North American Spine Society Acromed Research Grant: The Role of Transforming Growth Factor-Beta in the Spinal Cord Response to Acute Spinal Trauma. October 1993.

Academic Responsibilities: Faculty: Spine Fellowship Program – University of Colorado

Assistant Clinical Professor UC

Cooper Union Engineering School: EID 122 Biomaterials Assistant Instructor 1988 - 1992

EID 125 Biomechanics Assistant Instructor 1988 - 1992

Columbia University Anatomy Lab Instructor 1983 Faculty:

Practical Anatomy Workshop: Spinal Fracture Treatment, St. Louis, University, St. Louis, Missouri, April 1993.

British Cervical Spine Society: Cervical Instrumentation Workshop, Glasgow, Scotland, November 1993.

Surgical Workshop using Anatomical Prosection: Thoracolumbar Spine Workshop, University College, London, November 1993.

Hands-on Workshop on Stabilization of the Craniovertebral Junction: Hannover, Germany, December 1993.

Anterior Column Support: Mystique, Myth and Truth, Research Institute International, Gainesville, Florida, January/February 1995.

Anterior Cervical Osteosynthesis: Indications, Techniques and Results, Research Institute International, Gainesville, Florida, February 1995.

International Spine Workshop, Bethesda National Naval Medical Center, Bethesda, Maryland, June 11-23, 1995.

Anterior Column Support of the Thoracolumbar Spine, Research Institute International, New York, New York, December 6-9, 1995.

International Spine Workshop, Bethesda National Naval Medical Center, Bethesda, Maryland, June 1996.

Anterior Column Support of the Cervical and Thoracolumbar Spine, Research Institute International, Nassau, November 1996.

Latest Techniques in the Management of Rheumatoid Cervical Spine, Spinal Science Advancement Foundation (SSAF), New York Symposium, Millennium Broadway Hotel, New York, December 1999.

Think Tank. Spinal Deformity: Challenges and Solutions of Surgical Treatment, Las Croabas, Puerto Rico, May 2000.

Pedicle Fixation in the Thoracic Spine. Memphis, Tennessee, September 22, 2000.

GICD - 10th Annual Advanced Course on the Surgical Management of Spinal Disorders, Beaver Creek, Colorado, January 2001.

Spine Education Summit (DePuy Acromed), Vail, Colorado, February 2001.

Pedicle Fixation in the Thoracic Spine. Memphis, Tennessee, February 10, 2001.

Thoracolumbar Workshop, Perth, Australia, April 2001.

Spondylolysis and Spondylolisthesis – Instructional Course #404, American Academy of Orthopedic Surgeons, San Francisco, California, February 2001. Pedicle Fixation in the Thoracic Spine. Memphis, Tennessee, May 19, 2001.

Pedicle Fixation in the Thoracic Spine. Half Moon Bay, California, October 13, 2001.

Pedicle Fixation in the Thoracic Spine. St. Louis, Missouri, February 2, 2002.

Spine Education Summit (DePuy Acromed), Vail, Colorado, February 2002.

Spondylolysis and Spondylolisthesis – Instructional Course #112, American Academy of Orthopedic Surgeons, Dallas, Texas, February 2002.

Advanced Deformity Training, Medtronic Sofamor Danek, Scottsdale, Arizona, April 2002.

Pedicle Fixation in the Thoracic Spine. Bethesda, Maryland, April 27, 2002.

Fundamentals of Spinal Deformity II – Scoliosis Research Society CME Course. Seattle, Washington, September 2002.

Spondylolysis and Spondylolisthesis – Instructional Course #370, American Academy of Orthopedic Surgeons, New Orleans, Louisiana, February 2003.

Spine Education Summit (DePuy Acromed), Vail, Colorado, March 2003.

Advanced Deformity Training, Medtronic Sofamor Danek, Scottsdale, Arizona, April 9-10, 2003.

3rd International Spine Symposium (DePuy), Athens, Greece, May 2003.

Global Spine (SSAF), Dana Point, California, June 2003.

10th International Meeting on Advanced Spine Techniques, Rome, Italy, July 2003. Study Group Meetings:

Medtronic Sofamor Danek Study Group Meeting, Memphis, Tennessee, February 2001

Medtronic Sofamor Danek Study Group Meeting, Amelia Island, Florida, May 2001

Medtronic Sofamor Danek Study Group Meeting, Chicago, Illinois, December 2001

Medtronic Sofamor Danek Study Group Meeting, Scottsdale, Arizona, April 2002

Medtronic Sofamor Danek Study Group Meeting, Chicago, Illinois, December 2002

Medtronic Sofamor Danek Study Group Meeting, Scottsdale, Arizona, April 2003

Presentations:

The Contribution of The Three Columns of The Spine to Rotational Stability. Scoliosis Research Society, 23rd Annual Meeting, Baltimore, Maryland, September 1988.

The Contribution of The Three Columns of The Spine to Rotational Stability. American Academy of Orthopaedic Surgeons, 56th Annual Meeting, Las Vegas, Nevada, February 1989.

Axial and Rotational Stability of the Spine. The International Society for the Study of the Lumbar Spine, 16th Annual Meeting, Tokyo, Japan, May 1989.

The Effect of the Three Columns of the Spine on the Instantaneous Axis of Rotation. Scoliosis Research Society, 24th Annual Meeting, Amsterdam, Holland, September 1989.

The Effect of the Three Columns of the Spine on Instantaneous Axis of Rotation. American Academy of Orthopaedic Surgeons, 57th Annual Meeting, New Orleans, Louisiana, February 1990.

Neurologic Injury in Spinal Trauma: Diagnosis, Prognosis and Treatment. Orthopaedic Grand Rounds, Brooklyn, New York, March 1990.

The Effect of the Three Columns of the Spine on the Instantaneous Axis of Rotation in Flexion. Scoliosis Research Society, 25th Annual Meeting, Honolulu, Hawaii, September 1990.

Two Stage Free Flap. New York Society of Hand Surgery, Resident's Meeting, New York, New York, May 1990.

The Effect of the Three Columns of the Spine on the Instantaneous Axis of Rotation in Flexion. American Academy of Orthopaedic Surgeons, 58th Annual Meeting, Los Angeles, California, March 1991.

Instantaneous Axis of Rotation as a Function of the Three Columns of the Spine. North American Spine Society, 6th Annual Meeting, Denver, Colorado, July 1991.

Hemivertebra Resection: An Analysis of the Technique. Spine Science and Management, New Orleans, Louisiana, November 1992. Role of Lumbar Facet Joints in Spinal Stability: Identification of Alternative Paths of Loading. American Academy of Orthopaedic Surgeons, 60th Annual Meeting, San Francisco, California, February 1993.

Preoperative Spinal Canal Investigation in "Large" Adolescent Idiopathic Scoliosis Curves: Scoliosis Research Society, 28th Annual Meeting, Dublin, Ireland, September 1993.

Fresh Frozen Allograft For Posterior Spinal Fusions in Neuromuscular Scoliosis: Scoliosis Research Society, 28th Annual Meeting, Dublin, Ireland, September 1993.

SSEP Monitoring of Upper Extremity Function During Spinal Deformity Surgery: Scoliosis Research Society, 28th Annual Meeting, Dublin, Ireland, September 1993.

Recognition of Proximal Thoracic Idiopathic Curves Treated With Cotrel-Dubousset Instrumentation: Scoliosis Research Society, 28th Annual Meeting, Dublin, Ireland, September 1993.

Preoperative Spinal Canal Investigation in "Large" Adolescent Idiopathic Scoliosis Curves: North American Society, 8th Annual Meeting, San Diego, California, October 1993.

Fresh Frozen Allograft For Posterior Spinal Fusions in Neuromuscular Scoliosis: North American Spine Society, 8th Annual Meeting, San Diego, California, October 1993.

Recognition of Proximal Thoracic Idiopathic Curves Treated With Cotrel-Dubousset Instrumentation: North American Spine Society, 8th Annual Meeting, San Diego, California, October 1993.

Preoperative Spinal Canal Investigation in "Large" Adolescent Idiopathic Scoliosis Curves Spine, Science and Management, New Orleans, Louisiana, November 1993.

Astrocyte Response to Spinal Cord Injury: An Immunohistochemical Investigation: Cervical Spine Research Society, 21st Annual Meeting, New York, December 1993.

Preoperative Spinal Canal Investigation in "Large" Adolescent Idiopathic Scoliosis Curves: American Academy of Orthopaedic Surgeons, 61st Annual Meeting, New Orleans, Louisiana, March 1994.

Fresh Frozen Allograft For Posterior Spinal Fusions in Neuromuscular Scoliosis: American Academy of Orthopaedic Surgeons, 61st Annual Meeting, New Orleans, Louisiana, March 1994.

SSEP Monitoring of Upper Extremity Function During Spinal Deformity Surgery: American Academy of Orthopaedic Surgeons, 61st Annual Meeting, New Orleans, Louisiana, March 1994.

Recognition of Proximal Thoracic Idiopathic Curves Treated with Cotrel-Dubousset Instrumentation: American Academy of Orthopaedic Surgeons, 61st Annual Meeting, New Orleans, Louisiana, March 1994.

Astrocyte Response to Spinal Cord Injury: An Immunohistochemical Investigation: American Spinal Injury Association, Philadelphia, Pennsylvania, April 1994.

SSEP Monitoring of Upper Extremity Function During Spinal Deformity Surgery: American Spinal Injury Association, Philadelphia, Pennsylvania, April 1994.

Characterization of Cellular and Molecular Events in Acute Spinal Cord Injury GICD 11th International Congress, Arcachon, France, May 1994. A Posterolateral Approach to Extreme Lateral Lumbar Disk Herniations, Society of British Neurologic Surgeons, Dundee, Scotland, September 1994.

Astrocyte Response to Spinal Cord Injury: An Immunohistochemical Investigation, North American Spine Society , Minneapolis, Minnesota, November 1994.

A Posterolateral Approach to Extreme Lateral Lumbar Disk Herniations, North American Spine Society , Minneapolis, Minnesota, November 1994.

Laminoplasty Augmentation of Spinal Canal Area Using a Novel Technique: A Computerized Morphometric Analysis, Cervical Spine Research Society, Baltimore, Maryland, December 1994.

Histology of the Atlantoaxial Joint in Rheumatoid Arthritis: A Clinico-Pathologic Correlation in 33 Surgical Cases, Cervical Spine Research Society, Baltimore, Maryland, December 1994.

Astrocytic Response to Spinal Cord Injury: An Immunohistochemical Investigation, American Academy of Orthopedic Surgeons, Orlando, Florida, February 1995.

Development and Analysis of a Three Dimensional Finite Element Model of a Lumbar Vertebra Using Impact Loading, American Academy of Orthopedic Surgeons, Orlando, Florida, February 1995.

A Novel Technique for Laminoplasty Augmentation of Spinal Canal Area Using Titanium Mini-Plate Stabilization: A Computerized Morphometric Analysis, North American Spine Society, Washington, DC, October 1995.

Histology of the Atlantoaxial Joint in Rheumatoid Arthritis: A Clinico-Pathologic Correlation in 33 Surgical Cases, North American Spine Society, Washington, DC, October 1995.

A Novel Technique for Laminoplasty Augmentation of Spinal Canal Area Using Titanium Mini-Plate Stabilization: A Computerized Morphometric Analysis, American Academy of Orthopedic Surgeon, February 1996.

A Novel Technique for Laminoplasty Augmentation of Spinal Canal Area Using Titanium Mini-Plate Stabilization: A Computerized Morphometric Analysis, American Academy of Orthopedic Surgeons, Specialty Day, February 1996.

Histology of the Chronic Rheumatoid Atlantoaxial Joints: Clinico-Pathologic Analysis of 33 Operative Cases, Japanese Scoliosis Research Society Meeting, Traveling Fellowship, Tokyo, Japan, May 1997.

Effect of Methylprednisolone on the Acute Spinal Cord Injury: A Histologic Investigation in a Rat Model, Korean Scoliosis Research Society Meeting, Traveling Fellowship, Pusan, Korea, June 1997.

Effect of Methylprednisolone on the Acute Spinal Cord Injury: A Histologic Investigation in a Rat Model, Scoliosis Research Society Meeting, St. Louis, Missouri, September 1997.

Report of SRS Traveling Fellowship 1997, Scoliosis Research Society Meeting, St. Louis, Missouri, September 1997.

Occipitocervical Biomechanics: Considerations in Posterior Fixation and Fusion, Taiwan Spine Society Meeting, National Taiwan University, Taipei Taiwan, May 1997. Effect of Methylprednisolone on the Acute Spinal Cord Injury: A Histologic Investigation in a Rat Model, American Academy of Orthopedic Surgeons , Spine Day, February 1998.

Craniocervical Junction Pathology; Surgical and Philosophical Approaches, 1998 Lakewood Orthopaedic Spine Symposium, Denver, Colorado, November 1998.

Pedicle Screw Fixation in Thoracic AIS: Is This An Anatomically Viable Technique, 6 th International Meeting on Advanced Spine Techniques (IMAST), Vancouver, BC, Canada, July 1999.

Craniocervical Junction Pathology: An Algorithm for Treatment, 6 th International Meeting on Advanced Spine Techniques (IMAST), Vancouver, BC, Canada, July 1999.

Biomechanical Analysis of Multiple Smith Robinson versus Multilevel Corpectomy in a Human Cadaveric Model, 1999 Lakewood Orthopaedic Spine Symposium, Denver, Colorado, November 1999.

Pedicle Screw Fixation in Thoracic AIS: Is This An Anatomically Viable Technique, Scoliosis Research Society Meeting, San Diego, California, August 1999.

Biomechanical Analysis of Multiple Smith Robinson versus Multilevel Corpectomy in a Human Cadaveric Model, Cervical Spine Research Society Meeting. Seattle, Washington, 1999.

Latest Techniques in the Management of the Rheumatoid Cervical Spine, Spine Surgery for the Next Millennium: New Techniques and Technologies, New York, New York, December 1999.

Revision Cervical Spine Surgery, Spine Surgery for the Next Millennium: New Techniques and Technologies, New York, New York, December 1999.

Thoracic Pedicle versus Pedicle/Rib Fixation: A Biomechanical Study, [abstract] 7 th International Meeting on Advanced Spine Techniques, Barcelona, Spain, July 2000.

Posterior Spinal Fusion versus 360 Fusion in a Calf Spine Model: A Biomechanical Analysis of Motion at the Instrumented and Adjacent Uninstrumented Segments, [abstract] 7 th International Meeting on Advanced Spine Techniques, Barcelona, Spain, July 2000.

Central and Juxta-Endplate Vertebral Body Screw Placement: A Biomechanical Analysis in a Human Cadaveric Model, [abstract] 7 th International Meeting on Advanced Spine Techniques, Barcelona, Spain, July 2000.

Platelet Calmodulin Levels: A Predictor of Curve Progression in AIS, [paper] North American Spine Society, New Orleans, Louisiana, October 2000.

Thoracic Pedicle versus Pedicle/Rib Fixation: A Biomechanical Study, [paper] North American Spine Society, New Orleans, Louisiana, October 2000.

The Efficacy of Interbody Support With Anterior Instrumentation in AIS, [poster] North American Spine Society, New Orleans, Louisiana, October 2000.

Central and Juxta-endplate Vertebral Body Screw Placement: A Biomechanical Analysis, [paper] North American Spine Society, New Orleans, Louisiana, October 2000. Thoracic Pedicle versus Pedicle/Rib Fixation: A Biomechanical Study, [paper] Scoliosis Research Society – 35 th Annual Meeting, Cairns, Queensland, Australia, October 2000.

Anterior Single Rod Instrumentation in Thoracolumbar Adolescent Idiopathic Scoliosis With and Without the Use of Interbody Structural Support, [paper] Scoliosis Research Society – 35 th Annual Meeting, Cairns, Queensland, Australia, October 2000.

Platelet Calmodulin Levels in Adolescent Idiopathic Scoliosis (AIS): A Predictor of Curve Progression and Severity, [paper] Scoliosis Research Society – 35 th Annual Meeting, Cairns, Queensland, Australia, October 2000.

Central and Juxta-endplate Vertebral Body Screw Placement: A Biomechanical Analysis in a Human Cadaveric Model, [paper] Scoliosis Research Society – 35 th Annual Meeting, Cairns, Queensland, Australia, October 2000.

Posterior Spinal Fusion versus 360 Fusion in a Calf Spine Model: A Biomechanical Analysis of Motion at the Instrumented and Adjacent Uninstrumented Segments, [poster] Scoliosis Research Society – 35 th Annual Meeting, Cairns, Queensland, Australia, October 2000.

Sacro-pelvic Fixation in Spinal Deformities, Spinal Deformity: Challenges and Solutions of Surgical Treatment Think Tank, El Conquistador, Puerto Rico, May 2000.

Rheumatoid Arthritis of the Cervical Spine and Techniques for Management, 11 th Annual Colorado Spine Symposium Panorama Orthopaedics, November 10, 2000.

Survey of the Cervical Spine in a Population of Adults with Down Syndrome, Cervical Spine Research Society Meeting, Charleston, South Carolina, November 2000.

Osteotomy of the Spine as Treatment for Fixed Spinal Deformity After Spinal Trauma, Classic and Contemporary Insights in Spine Surgery - GICD New York, New York, December 2000.

Diagnosis and Treatment of Primary Tumors of the Spine, Classic and Contemporary Insights in Spine Surgery - GICD New York, New York, December 2000.

Cervicothoracic Junction Problems and Solutions, GICD - 10 th Annual Course on the Surgical Management of Spinal Disorders, Beaver Creek, Colorado, January 2001.

Posterior Cervical Decompression: Laminectomy vs Laminoplasty – Indications and Techniques, GICD - 10 th Annual Course on the Surgical Management of Spinal Disorders, Beaver Creek, Colorado, January 2001.

Adjacent Segment Syndrome, GICD - 10 th Annual Course on the Surgical Management of Spinal Disorders, Beaver Creek, Colorado, January 2001.

Cervical Spine: Considerations for Posterior Biomechanics and Instrumentation, DePuy AcroMed national Sales Meeting, Tucson, Arizona, January 2001.

Low Grade Isthmic/Lytic Spondylolisthesis in Adults [paper], American Academy of Orthopedic Surgeons, San Francisco, California, February 2001.

Interbody Fusion Techniques. [lecture] Thoracolumbar Workshop, Perth, Australia, April 2001. Thoracic and Lumbosacral Landmarks. [lecture] Thoracolumbar Workshop, Perth, Australia, April 2001.

Surgical Approaches to the Posterior Thoracic & Lumbar Spine: Anatomy & Operative Considerations. [lecture]. Thoracolumbar Workshop, Perth, Australia, April 2001.

Thoracic Pedicle Screw Versus Thoracic Pedicle/ Rib Screw Fixation: A Biomechanical Study. [paper] Spine Society of Australia Meeting, Fremantle, Australia, April 2001.

Transition Zone Syndrome: Iatrogenic Sequela of Surgery or Natural History?, [paper] 8 th International Meeting on Advanced Spine Techniques, Paradise Island, Bahamas, July 2001.

Traumatic Sacral Spondylolisthesis Following Instrumentation for Spinal Deformity [paper] Scoliosis Research Society – 36 th Annual Meeting, Cleveland, Ohio, September 2001.

CT Scan Accuracy of “Free Hand” Thoracic Pedicle Screw Placement in Pediatric Spinal Deformity. [poster] Scoliosis Research Society – 36 th Annual Meeting, Cleveland, Ohio, September 2001.

Preoperative MRI Screening for Surgical Decision Regarding Approach for Anterior Cervical Spine Fusion. [poster] Scoliosis Research Society – 36 th Annual Meeting, Cleveland, Ohio, September 2001.

Traumatic Sacral Spondylolisthesis Following Instrumentation for Spinal Deformity. [paper] Scoliosis Research Society – 36 th Annual Meeting, Cleveland, Ohio, September 2001.

Rheumatoid Arthritis of the Cervical Spine & Techniques for Management, 12 th Annual Colorado Spine Symposium Panorama Orthopaedics, November 9, 2001.

Biomechanical and Computer Analyses of the Structural Properties of Anterior and Posterior Instrumentation for Occipitocervical Fusion. [paper] Cervical Spine Research Society-29 th Annual Meeting. PRIVATE Monterey, California, November 2001.

Radiographic And Biomechanical Analysis Of Multilevel Reconstruction Of The Cervical Spine With The Smith-Robinson Corpectomy Techniques With And Without Anterior Plates In A Human Cadaveric Model. [paper] Cervical Spine Research Society-29 th Annual Meeting. PRIVATE Monterey, California, November 2001.

Dysphagia After Multilevel Anterior Cervical Arthrodesis: A Clinical and Cineradiographic Evaluation. [paper]. Cervical Spine Research Society-29 th Annual Meeting. PRIVATE Monterey, California, November 2001.

Bioactive Bone Cement: The Solution for Osteolysis [paper], 9 th International Meeting on Advanced Spine Techniques, Montreux, Switzerland, May 2002.

Radiographic & Biomechanical Analysis of Multilevel Reconstruction of the Cervical Spine Smith- Robinson vs. Corpectomy Techniques with and without Anterior Cervical Plates: A Human Cadaveric Model [paper], 9 th International Meeting on Advanced Spine Techniques, Montreux, Switzerland, May 2002.

Bioactive Bone Cement: The Solution for Osteolysis [paper], European Cervical Spine Research Society, Paris, France, June 2002. Anterior and Posterior Instrumentation for Occipitocervical Stabilization: A Biomechanical and Computer Analyses [paper], European Cervical Spine Research Society, Paris, France, June 2002.

Ethicon Endo-surgery, Cincinnati, OH, July 2002.

Attenuation of Ciliary Neurothropic Factor (CNTF) in Acute Spinal Cord Injury (ASCI) Treated with Intravenous Methylprednisolone (MP) [Paper], Scoliosis Research Society – 37 th Annual Meeting, Seattle, Washington, September 2002.

Survey of the Cervical Spine in a Population of Adults with Down Syndrome [Paper], Scoliosis Research Society – 37 th Annual Meeting, Seattle, Washington, September 2002.

Bioactive Bone Cement” The Solution for Osteolysis and Late Implant Loosening [Paper], Scoliosis Research Society – 37 th Annual Meeting, Seattle, Washington, September 2002.

Reliability of Radiographic Parameters for Scoliosis Evaluation [Paper], Scoliosis Research Society – 37 th Annual Meeting, Seattle, Washington, September 2002.

An Analysis of Patient and Parent Assessment of Deformity in Idiopathic Scoliosis Using the Water Reed Visual Assessment Scale [Paper], Scoliosis Research Society – 37 th Annual Meeting, Seattle, Washington, September 2002.

Adolescent Idiopathic Scoliosis: Current Concepts for Classification & the Biomechanics of Posterior Spinal Instrumentation (PSI), 12th Annual Colorado Spine Symposium Panorama Orthopaedics, November 8, 2002.

Instrumentation of the Cervical Thoracic Junction: A Biomechanical Comparison of Thoracic Pedicle Screws vs. Thoracic Hooks as Distal Anchors for Long Constructs [paper], Cervical Spine Research Society, Miami, Florida, December 2002.

Interobserver Variability in Identifying End, Neutral and Stable Vertebra in Adolescent Idiopathic Scoliosis [Paper], Scoliosis Research Society – 38 th Annual Meeting, Quebec, September 2003.

MSD Spinal Deformity Group Radiographic Measurement Manual: Spondylolisthesis [Paper], Scoliosis Research Society – 38 th Annual Meeting, Quebec, September 2003.

A multicenter clinical and radiographic analysis of anterior and posterior surgical techniques for treatment of “single overhang” Thoracic AIS [Paper], Scoliosis Research Society – 38 th Annual Meeting, Quebec, September 2003.

The Importance of Spino-Pelvic Balance After Spinal Instrumentation for High Grade Developmental Spondylolisthesis [Paper], Scoliosis Research Society – 38 th Annual Meeting, Quebec, September 2003.

A multicenter clinical and radiographic analysis of anterior and posterior surgical techniques for treatment of thoracolumbar/lumbar AIS: the Current state of the Art [Paper], Scoliosis Research Society – 38 th Annual Meeting, Quebec, September 2003.

End Organ Effects of High Dose of Human Equivalent Methylprednisolone in a Spinal Cord Injury Rat Model [Paper], Scoliosis Research Society – 39 th Annual Meeting, Buenos Aires, Argentina, September 2004. Restoration of Thoracic Sagittal Kyphosis Following Operative Treatment for Adolescent Idiopathic Scoliosis: A Comparison of Three Surgical Approaches [Paper], Scoliosis Research Society – 39 th Annual Meeting, Buenos Aires, Argentina, September 2004.

Scientific Exhibits:

Haher TR, Lospinuso M, O'Brien MF, Cataldo J, Weisman T: The Contribution of the Three Columns of the Spine to Spinal Stability: A Biomechanical Study. Scoliosis Research Society, 22nd Annual Meeting, San Francisco, California, September 1987.

Haher TR, O'Brien MF, Chow G, Valenza J, Welin D: The Contribution of the Three Columns of the Spine to Rotational Stability. Scoliosis Research Society, 23rd Annual Meeting, Baltimore, Maryland, September 1988.

Haher TR, O'Brien MF, Chow G, Valenza J, Welin D: The Contribution of the Three Columns of the Spine to Rotational Stability: A Biomechanical Model. American Academy of Orthopaedic Surgeons, 56th Annual Meeting, Las Vegas, Nevada, 1989.

Haher TR, O'Brien MF, Chow G, Valenza J, Welin D: The Contribution of the Three Columns of the Spine to Rotational Stability: A Biomechanical Model. American Spinal Injury Association, Las Vegas, Nevada, April 1989.

Haher TR, Felmly WT, O'Brien MF, Welin D: The Instantaneous Axis of Rotation as a Function of the Three Columns of the Spine. Scoliosis Research Society, 24th Annual Meeting, Amsterdam, Holland, September 1989.

Haher TR, O'Brien MF, Choueka J: The Instantaneous Axis of Rotation as a Function of the Three Columns of the Spine. American Academy of Orthopaedic Surgeons, 57th Annual Meeting, New Orleans, Louisiana, 1990.

Haher TR, O'Brien MF, Felmly WT: The Effect of the Three Columns of the Spine on the Instantaneous Axis of Rotation in Flexion. Scoliosis Research Society, 25th Annual Meeting, Honolulu, Hawaii, September 1990.

Haher TR, O'Brien MF, Felmly WT: The Effect of the Three Columns of the Spine on the Instantaneous Axis of Rotation in Flexion. American Academy of Orthopaedic Surgeons, 58th Annual Meeting, Washington, DC, March, 1991.

Monsanto E, Caligirui D, O'Brien MF: Two Stage Free Flap. American Society for Reconstructive Microsurgery, 6th Annual Meeting, Toronto, Canada, September 1990.

Haher TR, O'Brien MF, Dryer JW: Lumbar Facet Joints in Spinal Stability, Scoliosis Research Society, 27th Annual Meeting, Kansas City, Missouri, September 1992.

Haher TR, O'Brien MF, Dryer JW: Role of the Lumbar Facet Joints in Spinal Stability: Identification of Alternative Paths of Loading. American Academy of Orthopaedic Surgeons, 60th Annual Meeting, San Francisco, California, February 1993. O'Brien MF, Bridwell KH, Lenke LG, Baldus C, Blanke K: "De Novo" Degenerative Scoliosis: Guidelines for Evaluation and Treatment. Scoliosis Research Society, 28th Annual Meeting, Dublin, Ireland, September 1993.

Haher TR, O'Brien MF, Dryer JW: Role of the Lumbar Facet Joints in Spinal Stability: Identification of Alternative Paths of Loading. Scoliosis Research Society, 28th Annual Meeting, Dublin, Ireland, September 1993.

O'Brien MF, Bridwell KH, Lenke LG, Baldus C, Blanke K: "De Novo" Degenerative Scoliosis: Guidelines For Evaluation and Treatment. North American Spine Society, 8th Annual Meeting, San Diego, California, October 1993.

A Novel Technique for Laminoplasty Augmentation of Spinal Canal Area Using Titanium Mini- Plate Stabilization: A Computerized Morphometric Analysis, North American Spine Society, Washington DC, October 1995.

A Posterolateral Microsurgical Approach to Extreme Lateral Lumbar Disc Herniations, American Academy of Orthopedic Surgeons, Atlanta, Georgia, February 1996.

A Novel Technique for Laminoplasty Augmentation of Spinal Canal Area Using Titanium Mini-Plate Stabilization: A Computerized Morphometric Analysis, American Academy of Orthopedic Surgeons , Atlanta, Georgia, February 1996.

O'Brien MF, Hahn J, Smith DAB, Lowe TG, Vraney RT, Tahernia AD, Haher T, Merola A, Yeung A: Biomechanics of Anterior VS Posterior Plating of the Occipitocervical Junction: A Computer Analysis. 6 th International Meeting on Advanced Spine Techniques (IMAST), [poster] Vancouver, BC, Canada, July 1999.

Tahernia AD, Lowe TG, Vraney RT, O'Brien MF, Kong Y, Smith DAB, MSc: Unilateral Transforaminal Posterior Lumbar Interbody Fusion: Indications, Techniques, and Results. 6 th International Meeting on Advanced Spine Techniques (IMAST), [poster] Vancouver, BC, Canada, July 1999.

AD Tahernia M.D., MF O'Brien, M.D., TG Lowe, M.D., RT Vraney, M.D., DAB Smith, MSc: An Algorithm for Treatment of Deformity of the Craniocervical Junction, SRS Annual Meeting, [poster] San Diego, California, September 1999.

Pedicle Screw Fixation in Adolescent Idiopathic Scoliosis (AIS): Is This an Anatomically Viable and Safe Technique? SRS Annual Meeting, [poster] San Diego, California, September 1999.

Tahernia AD, Lowe TG, Vraney RT, O’Brien MF, Kong Y, Smith D: Unilateral Transforaminal Posterior Lumbar Interbody Fusion: Indications and Results. SRS Annual Meeting, [paper] San Diego, California, September 1999.

MF O'Brien, M.D., AD Tahernia,M.D., TG Lowe, M.D., RT Vraney, M.D., DAB Smith, MSc, An Algorithm for Treatment of Deformity of the Craniocervical Junction, Cervical Spine Research Society Meeting. Seattle, Washington 1999.

Michael F. O’Brien, M.D., David A.B. Smith, M.Sc., Josh V. Hahn, B.S., Thomas G. Lowe, M.D., Robert T. Vraney, M.D., A. David Tahernia, M.D., Thomas R. Haher, M.D., Andrew A. Merola, M.D., and Amy Yeung, M.Eng.: Biomechanics of Anterior vs Posterior Plating of the Occipitocervical Junction: A Computer Analysis, Cervical Spine Research Society Meeting. Seattle, Washington 1999PRIVATE .

Michael F. O’Brien MD, Robert T. Vraney MD, Jeffrey B. Wood MD, Thomas G. Lowe MD, David A.B. Smith MD, David Fitzgerald BSME, Paul R. Alongi MD, Thomas Haher MD, Andrew Merola MD, Susan James PhD: Radiographic and Biomechanical Analysis of multilevel Smith- Robinson Vs. Corpectomy Reconstruction of the Cervical Spine: A Human Cadaveric Model. 7 th International Meeting on Advanced Spine Techniques (IMAST), Barcelona, Spain, July 2000.

Paul Alongi MD, Thomas Lowe MD, Michael O’Brien MD, Jeffrey Wood MD: The Efficacy Of Interbody Structural Support With Anterior Instrumentation In Thoracolumbar Adolescent Idiopathic Scoliosis, North American Spine Society, New Orleans, Louisiana, October 2000.

Robert E. Donnelly MD, Michael F. O’Brien MD, Paul R. Alongi MD, Thomas G. Lowe MD, Thomas F. Dwyer MD: Posterior Hemivertebrae Resection for Congenital Kyphoscoliosis: A Technique, Scoliosis Research Society Meeting 35 th Annual Meeting, Cairns, Australia, October 2000.

Robert E. Donnelly MD, David A.B. Smith MSc, Michael F. O’Brien MD, Thomas G. Lowe MD, David G. Fitzgerald BSME, The Biomechanical Properties of Fresh-Frozen Human Vertebral Bodies: Considerations for Use as Allograft Interbody Spacers in Cervical Spinal Reconstruction, Cervical Spine Research Society Meeting. Charleston, South Carolina, November 2000.

Dwyer TF, O’Brien MF, DeWald C, Gelb DG, Flawn LB, Lowe TG, Donnelly RE: Traumatic Sacral Spondylolisthesis Following Instrumentation for Spinal Deformity [paper] Scoliosis Research Society – 36 th Annual Meeting, Cleveland, Ohio, September 2001.

O’Brien MF, Lowe TG, Wood JB, Eule J, Dwyer TF, Donnelly RE, Smith DAB: Transition Zone Syndrome: Iatrogenic Sequela of Surgery or Natural History?, [paper] 8 th International Meeting on Advanced Spine Techniques, Paradise Island, Bahamas, July 2001

Survey of the Cervical Spine in a Population of Adults with Down Syndrome [poster], American Academy of Orthopedic Surgeons, Dallas, Texas, February 2002.

Posterior Pullout Failure of Deformity Constructs in the Thoracic Spine: A Biomechanical Evaluation of Traditional Hook and Thoracic Pedicle Screw Constructs [e-poster], 9 th International Meeting on Advanced Spine Techniques, Montreux, Switzerland, May 2002.

Clinical and Outcomes Analysis of the Midline vs. Wiltse Approach to the Lumbar Spine: A Novel Application of an Established Surgical Approach [e-poster], 9 th International Meeting on Advanced Spine Techniques, Montreux, Switzerland, May 2002.

An Evaluation of Screw and Thread Design for Occipital Fixation [e-poster], 9 th International Meeting on Advanced Spine Techniques, Montreux, Switzerland, May 2002.

Dysphagia After Multilevel Anterior Cervical Arthrodesis: A Clinical and Cineradiographic Evaluation [e-poster], 9 th International Meeting on Advanced Spine Techniques [e-poster] , Montreux, Switzerland, May 2002.

Traumatic Sacral Spondylolisthesis: A Consequence of Spinal Instrumentation and Fusion to the Sacrum in the Elderly [e-poster], 9 th International Meeting on Advanced Spine Techniques, Montreux, Switzerland, May 2002. Vertebral Endplate Strength as a Function of Position: A Biomechanical Impactor Study [e-poster], 9 th International Meeting on Advanced Spine Techniques, Montreux, Switzerland, May 2002.

Lateral Pullout Failure of Deformity Constructs in the Thoracic Spine: A biomechanical Evaluation of Traditional Hook and Thoracic Pedicle Screw Constructs [e-poster], 9 th International Meeting on Advanced Spine Techniques, Montreux, Switzerland, May 2002.

Relevance of the Cross Sectional Area and Geometry of Interbody Spacers in Anterior Spinal Reconstruction: A Biomechanical Study in a Human Cadaveric Model [e-poster], 9 th International Meeting on Advanced Spine Techniques, Montreux, Switzerland, May 2002.

Chiari I Malformation Associated with Syringomyelia and Scoliosis: A 20-Year Review of Surgical and Non-Surgical Treatment in a Pediatric Population [poster], European Cervical Spine Research Society, Paris, France, June 2002.

Radiographic & Biomechanical Analysis of Multilevel Reconstruction of the Cervical Spine Smith- Robinson vs. Corpectomy Techniques with and without Anterior Cervical Plates: A Human Cadaveric Model [poster], European Cervical Spine Research Society, Paris, France, June 2002.

Human Cadaveric Vertebral Endplate Strength Study: As a Function of Position & Cage Size [poster], European Cervical Spine Research Society, Paris, France, June 2002.

Accuracy and Efficacy of Thoracic Pedicle Screws in Curves over 90 Degrees [E-Poster], Scoliosis Research Society – 37 th Annual Meeting, Seattle, Washington, September 2002.

Adolescent Idiopathic Scoliosis Radiographic Measurement Manual [E-Poster], Scoliosis Research Society – 37 th Annual Meeting, Seattle, Washington, September 2002.

Attenuation of Ciliary Neurothropic Factor (CNTF) in Acute Spinal Cord Injury (ASCI) Treated with Intravenous Methylprednisolone (MP) [Poster], Scoliosis Research Society – 37 th Annual Meeting, Seattle, Washington, September 2002.

Reliability of Radiogrpahic Parameters for Scoliosis Evaluation [Poster], Scoliosis Research Society – 37 th Annual Meeting, Seattle, Washington, September 2002.

Interobserver Variability In Identifying End, Neutral And Stable Vertebrae In Adolescent Idiopathic Scoliosis [e-poster], 10th International Meeting on Advanced Spine Techniques (IMAST), Rome, Italy, July 2003.

Finite element modeling of thoracic pedicle screw constructs [e-poster],10th International Meeting on Advanced Spine Techniques (IMAST), Rome, Italy, July 2003.

Comparison of Digital versus Manual Radiographic Measurements for Scoliosis Evaluation [E- Poster], Scoliosis Research Society – 38 th Annual Meeting, Quebec, September 2003.

Finite Element Modeling of Thoracic Pedicle Screw Constructs [Poster], Scoliosis Research Society – 38 th Annual Meeting, Quebec, September 2003.

Surgical Management of the Cervical Spine in a Population of Adults with Down Syndrome [Poster], Scoliosis Research Society – 38 th Annual Meeting, Quebec, September 2003. Thoracic Spine Construct Stability is Dependent upon the Number of and Configuration of Pedicle Screws [Poster], Scoliosis Research Society – 39 th Annual Meeting, Buenos Aires, Argentina, September 2004.

STUDIES Radiographic and Clinical Outcome Assessment of “Single Curves” in Adolescent Idiopathic Scoliosis: A Pilot Study Prelude to a Prospective Investigation. Summary: The main purpose of this pilot study is to develop and define the necessary radiographic (process) and clinical (patient) outcome measures to evaluate patients with single curve, adolescent idiopathic scoliosis (AIS) being treated with current surgical techniques.

Colorado Spine Symphony Study. Summary: The Symphony Platelet Concentrate System is designed to be used for the safe and rapid preparation of autologous platelet-rich-plasma (PRP) from a small sample of blood immediately prior to surgery. The PRP can be mixed with autograft and allograft bone grafting materials prior to implantation to assist in the rate and reliability of achieving a fusion.

A Randomized Multi-Center Study to Evaluate the Safety and Efficacy of the Cervical I/F Cage for Anterior Cervical Fusion. Summary: The purpose of this randomized multi-center clinical trial is to determine the safety and effectiveness of the Cervical I/F Cage for interbody fusion in treatment of degenerative disc disease in one or two adjacent levels in the cervical spine.

BIBLIOGRAPHY:

I. ABSTRACTS Haher TR, Devlin V, Felmly WT, O'Brien MF, Wilen D, Perrier G, Chow G, Valenza J, Choueka J, Vassiliou A, Parrish S, Ahmad J: The Contribution of the Three Columns of the Spine to Spinal Stability in Compression and Torsion. Orthopaedic Transactions, 14(1):31, 1990.

Haher TR, Felmly WT, O'Brien MF, Welin D, Perrier G, Devlin V, Choueka J, Vassiliou A, Chow G, Ahmad J: The Instantaneous Axis of Rotation as a Function of the Three Columns of the Spine. Orthopaedic Transactions, 14(1):728, 1990.

Haher TR, Felmly WT, Welin D, Choueka J, O'Brien MF, Perrier G, Vassiliou A: The Instantaneous Axis of Rotation as a Function of the Three Columns of the Spine. Orthopaedic Transactions, 14(1):786, 1990.

Haher TR, Bergman M, O'Brien MF, Felmly WT, Masciale J, Choueka J, Goldstein J, Chow G, Vassiliou A: The Effects of Three Columns of the Spine on the Instantaneous Axis of Rotation in Flexion. Orthopaedic Transactions, 15:(1)730, 1991.

Haher TR, Lospinuso M, Tozzi J, O'Brien MF, Devlin V, Weisman T, Tennant R, Valenza J, Parrish S, Ahmad J, Caltaldo J: The Contribution of the Three Columns of the Spine to Spinal Stability: A Biomechanical Model. Orthopaedic Transactions, 12:(1):262, 1988.

Haher TR, O'Brien MF, Dryer J, Schloub J, Orchowski J: The Role of the Lumbar Facet Joints in Spinal Stability: Identification of Alternative Paths of Loading. Orthopaedic Transactions, 17:(1):130, 1991. A Novel Technique for Laminoplasty Augmentation of Spinal Canal Area Using Titanium Mini-Plate Stabilization: A Computerized Morphometric Analysis, Orthopedic Transactions in Press, Volume 20, No. 1, Page 16, 1996.

II. JOURNAL ARTICLES Haher TR, Felmly WT, O'Brien MF, Baruch H, Velanza J, Parrish S, Ahmad J, Langone M: The Contribution of the Three Columns of the Spine to Rotational Stability. Spine, 14(7):663-669, 1989.

Haher TR, Felmly WT, O'Brien MF, Welin D, Perrier G, Ahmad J, Valenza J, Parrish S: The Contributions of the Three Columns of the Spine to Spinal Stability: A Biomechanical Model. Paraplegia, 27:432-439, 1989.

Haher TR, Bergman M, O'Brien MF, Felmly WT: The Effect of the Three Columns of the Spine on the Instantaneous Axis of Rotation in Flexion and Extension. Spine, 16(8s):312, 1991.

Haher TR, O'Brien MF: Instantaneous Axis of Rotation as a Function of the Three Columns of the Spine. Spine, 17(6s):149-153, 1992.

O'Brien M, Haher TR: Biomechanics of the Spine in Sports. Clinics in Sports Medicine, 12(3): 449- 464, 1993.

O'Brien MF, Bridwell KH, Lenke LG, Schoenecker PL: Intracanalicular Osteochondroma Producing Spinal Cord Compression in Hereditary Multiple Exostoses. Journal of Spinal Disorders, 7(3): 236- 241, 1994.

Bridwell KH, Sedgewick, TA, O'Brien MF, Lenke LG, Baldus C: The Role of Fusion and Instrumentation in the Treatment of Degenerative Spondylolisthesis With Spinal Stenosis. Journal of Spinal Disorders, 6(6): 461-472, 1994.

O'Brien MF, Lenke LG, Bridwell KH, Blanke K: Preoperative Spinal Canal Investigation in Adolescent Idiopathic Scoliosis Curves  70. Spine, 19(14):1606-1610, 1994.

O'Brien MF, Lenke LG, Bridwell KH, Padberg A, Stokes M: Evoked Potential Monitoring of the Upper Extremities During Thoracic and Lumbar Spinal Deformity Surgery: A Prospective Study. Journal of Spinal Disorders, 7(4):277-284, 1994.

Lenke LG, Bridwell KH, O'Brien MF, Baldus C, Blanke K: Recognition and Treatment of the Proximal Thoracic Curve in Adolescent Idiopathic Scoliosis Treated with Cotrel- Dubousset Instrumentation. Spine, 19(14):1589-1597, 1994.

O'Brien MF, Lenke LG, Bridwell KH, Joyce ME: Astrocyte Response and Transforming Growth Factor-beta Localization in Acute Spinal Cord Injury, Spine, 19(20):2321-2330, 1994.

Haher TR, O’Brien MF, Dryer JW, Nucci R, Zipnick R, Leone DJ: The Role of the Lumbar Facet Joints in Spinal Stability, Identification of Alternative Paths of Loading. Spine 19(23):2667-2671, 1994.

Bridwell KH, O'Brien MF, Lenke LG, Baldus C, Blanke K: Posterior Spinal Fusion Supplemented With Only Allograft Bone in Paralytic Scoliosis: Does it Work? Spine, 19(23): 2658-2666, 1994.

O’Brien MF, Peterson D, Crockard HA: A Posterolateral Microsurgical Approach to Extreme Lateral Lumbar Disc Herniations, Journal of Neurosurgery , 83:636-640, 1995 . Casey ATH, O’Brien MF, Kumar V, Crockard HA, Heyward R: Don’t Twist My Child’s Head Off : Iatrogenic Cervical Dislocations , British Medical Journal, 311:1212-1213, 1995.

O’Brien MF, Peterson D, Casey ATH, Crockard HA: A Novel Technique For Laminoplasty Augmentation of Spinal Canal Area Using Titanium Miniplate Stabilization: A Computerized Morphometric Analysis, Spine, 21(6):474-483,1996.

Lou J, Lenke LG, Xu F, O’Brien M: In-Vivo Bcl-2 Oncogene Neuronal Expression in the Rat Spinal Cord, Spine, 23(5):517-23, 1997.

O’Brien MF, Lenke LG, Mardjetko S, Lowe TG, Kong Y, Eck K, Smith D: Pedicle morphology in thoracic adolescent idiopathic scoliosis: Is pedicle fixation an anatomically viable technique? Spine, 25(18):2285-93, 2000.

Merola A, O’Brien MF, Castro BA, Smith DA, Eule JM, Lowe TG, Dwyer AP, Haher TR, Espat NJ: Histologic characterization of acute spinal cord injury treated with intravenous methylprednisolone. J Orthop Trauma, 16(3):155-61, 2002.

Lowe TG, Tahernia AD, O’Brien MF, Smith DA: Unilateral transforaminal posterior lumbar interbody fusion (TLIF): Indications, technique, and 2-year results. J Spinal Disord Tech, 15(1):31-8, 2002.

Casey AT, Crockard HA, Pringle J, O’Brien MF, Stevens JM: Rheumatoid arthritis of the cervical spine: Current techniques for management. Orthop Clin North Am, 33(2):291-309, 2002.

Eule JM, Erickson MA, O’Brien MF, Handler M: Chiari I malformation associated with syringomyelia and scoliosis: A twenty-year review of surgical and non-surgical treatment in a pediatric population. Spine 27(13):1451-5, 2002.

O’Brien MF, Casey AT, Crockard A, Pringle J, Stevens JM: Histology of the craniocervical junction in chronic rheumatoid arthritis: A clinicopathologic analysis of 33 operative cases. Spine 27(20):2245-54, 2002.

O’Brien MF: Low grade isthmic/lythic spondylolisthesis in adults. (Review) (76 Refs). Instructional Course Lectures 52:511-24, 2003.

Lowe TG, Alongi PR, Smith DA, O’Brien MF, Mitchell SL, Pinteric RJ: Anterior Single Rod Instrumentation for Thoracolumbar Adolescent Idiopathic Scoliosis with and without the Use of Structural Interbody Support. Spine 28(19)2232-41; discussion 2241-2, 2003

Sanders JO, Polly DW Jr, Cats-Baril W. Jones J, Lenke LG, O’Brien MF, Stephens Richards B, Sucato DJ; AIS Section of the Spinal Deformity Study Group: Analysis of Patient and Parent Assessment of Deformity in Idiopathic Scoliosis Using the Walter Reed Visual Assessment Scale. Spine 28(18):2158- 63, 2003.

Lowe TG, Hashim S, Wilson LA, O’Brien MF, Smith DA, Diekmann MJ, Trommeter J: A Biomechanical Study of Regional Endplate Strength and Cage Morphology as it Relates to Structural Interbody Support. Spine 29(21):2389-94, 2004.

Labelle H, Rousouly P, Berthonnaud E, Transfeldt E, O’Brien, M, Chopin D, Hresko T, Dimnet J: Spondylolisthesis, Pelvic Incidence, and Spinopelvic Balance: A Correlation Study. Spine 29(18):2049-2054, 2004. Labelle H, Roussouly P, Berthonnaud E, Dimnet J, O’Brien, MF: The Importance of Spino-Pelvic Balance in L5-S1 Developmental Spondylolisthesis: A Review of Pertinent Radiologic Measurements. Spine 30(S6):S27-S34, 2005.

Kuklo TR, Potter BK, O’Brien MF, Schroeder TM, Lenke LG, Polly DW Jr; Spinal Deformity Study Group: Reliability Analysis for Digital Adolescent Idiopathic Scoliosis Measurements. J Spinal Disord Tech 18(2):152-9, 2005

Kuklo TR, Potter BK, Polly DW Jr, O’Brien MF, Schroeder TM, Lenke LG: Reliability Analysis for Manual Adolescent Idiopathic Scoliosis Measurements. Spine 30(4):444-54, 2005.

Lowe TG, Enguidanos ST, Smith DA, Hashim S, Eule JM, O’Brien MF, Diekmann MJ, Wilson L, Trommeter JM: Single-rod Versus Dual-rod Anterior Instrumentation for Idiopathic Scoliosis: A Biomechanical Study. Spine 30(3):311-7, 2005.

Kuklo TR, Lenke LG, O’Brien MF, Lehman RA Jr, Polly DW Jr, Schroeder TM: Accuracy and Efficacy of Thoracic Pedicle Screws in Curves more than 90 Degrees. Spine 30(2):222-6, 2005.

Deviren V, Acaroglu E, Lee J, Fujita M, Serena H, Lenke LG, Polly D, Kuklo TR, O’Brien MF, Brumfield D, Puttlitz CM: Pedicle Screw Fixation of the Thoracic Spine: An In Vitro Biomechanical Study on Different Configurations. Spine 30(22):2530-2537.

Kuklo TR, O’Brien MF, Lenke LG, Polly DW, Sucato DS, Richards BS, Lubicky J, Ibrahim K, Kawakami N, King A; Spinal Deformity Study Group: AIS Section: Comparison of the Lowest Instrumented, Stable, and Lower End Vertebrae in “Single Overhang” Thoracic Adolescent Idiopathic Scoliosis; Anterior Versus Posterior Spinal Fusion. Spine 31(19):2232-6, 2006.

Macagno AE, O’Brien MF: Thoracic and Thoracolumbar Kyphosis in Adults. Spine 31(19 Suppl):S161-70, 2006.

Kuklo TR, Potter BK, Schroeder TM, O’Brien MF: Comparison of Manual and Digital Measurements in Adolescent Idiopathic Scoliosis. Spine 31(11):1240-6, 2006.

Sucato DJ, Agrawal S, O’Brien MF, Lowe TG, Richards SB, Lenke L: Restoration of Thoracic Kyphosis after Operative Treatment of Adolescent Idiopathic Scoliosis: Multicenter Comparison of Three Surgical Approaches. Spine 33(24):2630-6, 2008.

Labelle H, Roussouly P, Chopin D, Berthonnaud E, Hresko T, O’Brien M: Spino-pelvic Alignment after Surgical Correction for Developmental Spondylolisthesis. European Spine Journal 17(9):1170-6, 2008.

III. BOOK CHAPTERS

Haher TR, Felmly WT, O'Brien MF: Diagnosis and Treatment of Spinal Fractures. In: Bridwell KH, DeWald RL (eds.): The Textbook of Spinal Surgery (1st Edition). Philadelphia, J.B. Lippincott Company, 1991. Lenke LG, O'Brien MF: Treatment of Spine Fractures. In: Perry CR (ed.): The Handbook of Fractures. New York: McGraw Hill Publishing Co., 1994.

Haher TR, Felmly WT, O'Brien MF: Diagnosis and Treatment of Spinal Fractures. In: Bridwell KH, DeWald RL (eds): The Textbook of Spinal Surgery (2nd Edition). Philadelphia, J.B. Lippincott Company, 1995.

O'Brien MF, Lenke LG, Joyce ME: Pathophysiology and Treatment of Spinal Cord Injuries: Cellular and Molecular Mechanisms: In: Bridwell KH, DeWald RL (eds): The Textbook of Spinal Surgery (2nd Edition). Philadelphia, J.B. Lippincott Company, 1995.

O’Brien MF, Lenke LG: Spinal Fractures. In Dee R. (Ed) Textbook of Orthopedic Surgery 1996.

O’Brien MF, Sutterlin CE: Occipitocervical Biomechanics: Clinical and Biomechanical Implications for Posterolateral Occipitocervical Stabilization and Fusion. In: Haher TR (Ed) Spine State of the Art Review 1996.

O’Brien MF, Sandhu H: Spine Fracture Section Editor, Techniques in Fracture Fixation. Ed. Tornetta P, Mosby , Philadelphia 1997.

O’Brien MF: The Craniocervical Junction-Anterior Problems and Surgical Solutions. In Devlin VJ (ed): Anterior Spinal Column Surgery. Spine: State of the Art Review, Vol. 12, No. 3. Philadelphia, Hanley & Belfus, Inc., 1998.

O'Brien MF, Lowery GL, Pennisi AE: Surgical Management of Advanced Degenerative Disease of the Lumbar Spine with Multiplanar Deformity, The American Association of Neurological Surgeons, 225-233, 1999.

O’Brien MF: The Craniocervical Junction-Anterior Problems and Surgical Solutions. In Devlin VJ (ed): Anterior Spinal Column Surgery. Spine: State of the Art Review, Vol. 12, No. 3. Philadelphia, Hanley & Belfus, Inc., 1998.

O’Brien MF: Occipitocervical Junction: Decompression and Fusion. Haher TR, Merola AA (eds) Surgical Techniques of the Spine. Thieme Medical Publishers, Inc., 1999.

O’Brien MF, Jones AF: Complications of Anterior Spine Surgery. Lenke LG, Betz R, Harms J (eds), Modern Anterior Scoliosis Surgery, Quality Medical Publishers, Inc., 2000.

O’Brien MF, Shufflebarger HL: Treatment of Cervicothoracic Junction Pathology Using the Summit System. Kim DH, Vaccaro AR, Fessler RG (eds) Spinal Instrumentation. Thieme Medical Publishers, Inc., 2005.

O’Brien MF, Shufflebarger HL: MOSS MIAMI Instrumentation for Treatment of Thoracic Scoliosis and Kyphosis. Kim DH, Vaccaro AR, Fessler RG (eds) Spinal Instrumentation. Thieme Medical Publishers, Inc., 2005.

IV. INSTRUCTIONAL VIDEO 1. A Posterolateral Microsurgical Approach to Extreme Lateral Lumbar Disc Herniations, 1994 2. Transoral Resection of Clival Chordomas via an “Open-Door” Maxillotomy, 1994 Extracurricular Interests: Cabinetry and Furniture Building Metal Sculpture Printmaking Sailing Scuba Diving

References available upon request

Michael F O’Brien MD, Curriculum Vitae Updated DATE \@ "M/d/yyyy" 6/24/2009