Work Address: Institute of Medical Microbiology and Hygiene

Curriculum vitae

Name: Udo Reischl, Ph.D.

Work Address: Institute of Medical Microbiology and Hygiene University of Regensburg Franz-Josef-Strauss-Allee 11 D-93053 Regensburg, Germany Tel: ++49-941-944-6450 Fax: ++49-941-944-6402 E-mail: [email protected] www.udo-reischl.de

Date of Birth: 01.12.1963

Place of Birth: Deggendorf, Bavaria, Germany

Nationality: German

Family Status: Married, 1 Son, 1 Daughter

C.V. for Dr. Udo Reischl (September 2002) page 1 of 4 General Education

1969-1973 Primary School, Grafenau, Germany 1973-1982 High School, Grafenau May 1982 Graduation from High School

Scientific Education

1982 - 1985 Study of Chemistry Faculty of Chemistry, University of Regensburg, Regensburg, Germany

1985 - 1987 Study of Biochemistry Faculty of Biochemistry, Ludwig- Maximilians University, Munich

1987 - 1988 Diploma Thesis (Biochemistry) Faculty of Biochemistry, Prof. G. Isolation and characterization of the Hartmann, Ludwig-Maximilians restriction endonucleases Ecl XI and University, Munich, Germany Mcr I and Boehringer Mannheim GmbH, Penzberg, Germany

1989 - 1992 Ph.D. Thesis Boehringer Mannheim GmbH, Development of alternative strategies Penzberg, Germany for the in vitro amplification of nucleic and acids based on natural replication and Faculty of Biochemistry, Ludwig- transcription mechanisms Maximilians University, Munich, Germany

1992-1996 Group Leader Position Institute of Medical Microbiology and Molecular Diagnostics Hygiene (director: Prof. Dr. H. Wolf), University of Regensburg, Regensburg, Germany

Since 1996 Senior Scientist Institute of Medical Microbiology and Molecular Diagnostics Hygiene (Director: Prof. Dr. H. Wolf), University of Regensburg, Regensburg, Germany

C.V. for Dr. Udo Reischl (September 2002) page 2 of 4 Fields of Particular Expertise / Research  Cloning, expression and purification of recombinant proteins.  Development and clinical evaluation of recombinant antigens.  Since 1989 experience in the design and work with systems for in vitro amplification of nucleic acids (PCR, RT-PCR, LCR, NASBA, etc.).  Extensive experience in applied nucleic acid-based diagnostics.  Development of diagnostic test systems for clinical bacteriology and virology.  High-sensitive detection and identification of mycobacteria.

Achievements  Author of more than 100 scientific publications in the field.  Inventor position at several German, European and US patent applications dealing with the amplification or specific detection of nucleic acids.  Member of the "German Study Group on Mycobacteria" (AKM).  Member of the board E3 of the German Institute of Standardization (DIN) "Serological procedures for the diagnosis of infectious diseases".  Vice-chairman of the board AK E3/E9 of the German Institute of Standardization (DIN) "Molecular biology-based procedures for the detection of Mycobacteria".  Member of the study group "Molecular biology-based procedures for epidemiological typing of mycobacteria" of the German Association for Hygiene and Microbiology (DGHM).  Member of the Editorial Board of "BioTechniques".  Editor of a book entitled "Molecular Diagnostics of Infectious Diseases: Methods and Protocols", Methods in Molecular Medicine Series, Humana Press Inc., Totowa, USA.  Co-Editor of a book entitled "Quantitative PCR Protocols", Methods in Molecular Medicine Series, Humana Press Inc., Totowa, USA.  Co-Editor of a book entitled "Rapid Cycle Real-Time PCR: Methods and Applications – Microbiology and Food Analysis", Springer Press, Heidelberg, Germany.  Consultant activities for various diagnostic companies in the field of Molecular Diagnostics.  Member of the Advisory Board of SmartGene Inc., Zürich, Switzerland.

C.V. for Dr. Udo Reischl (September 2002) page 3 of 4  National Reference Laboratory for diagnostic PCR using AMPLICOR Mycobacterium tuberculosis, AMPLICOR HCV und COBAS AMPLICOR (accredited by Roche Diagnostics, Mannheim, Germany).  Reference Laboratory for diagnostic LightCycler applications in the field of Clinical Bacteriology (accredited by Roche Molecular Biochemicals, Mannheim, Germany)  Coordinator of the INSTAND proficiency panel studies "PCR-based detection of bacterial pathogens" and member of the quality maintenance board of the the German Association for Hygiene and Microbiology (DGHM).  Member of the Editorial Board of BioTechniques, Molecular Biotechnology, and Frontiers in Bioscience.  Member of the Advisory Board of Eaton Publishing, Westborough, MA.  Member of the Editorial Advisory Board for the Encyclopedia of Diagnostic Genomics and Proteomics (EDGP), Marcel Dekker Inc., New York.  Ad hoc reviewer for the following journals: Journal of Clinical Microbiology, BioTechniques, Journal of Virological Methods, International Journal of Systematic and Evolutionary Microbiology, Journal of Microbiological Methods, Emerging Infectious Diseases, Molecular Biotechnology, FEMS Immunology and Medical Microbiology.

C.V. for Dr. Udo Reischl (September 2002) page 4 of 4