Harold W. Jaffe, M.D.

Harold W. Jaffe, M.D.

Curriculum Vitae

Date of Birth: April 26, 1946 Place of Birth: Newton, Massachusetts Citizenship: U.S.A.

Degrees: University of Oxford M.A. by Resolution 2004

University of California M.D. 1971 Los Angeles, California

University of California A.B. 1967 Berkeley, California

Honors: Lifetime Scientific Achievement Award 2004 Centers for Disease Control and Prevention

Distinguished Service Medal 1992 U.S. Public Health Service

Unit Commendation 1991 U.S. Public Health Service

Meritorious Service Medal 1986 U.S. Public Health Service

Honor Award for Field Investigations and Services 1984 Centers for Disease Control

Commendation Medal 1984 U.S. Public Health Service

Unit Commendation 1981 U.S. Public Health Service

Alpha Omega Alpha 1971

1 Harold W. Jaffe, M.D.

Phi Beta Kappa 1967

Departmental Citation in Genetics, 1967 University of California, Berkeley

Certification:

Fellowship of the Faculty of Public Health of the Royal College of Physicians of the United Kingdom 2006

UK General Medical Council 2004

American Board of Internal Medicine Infectious Diseases 1980

American Board of Internal Medicine 1974

National Board of Medical Examiners 1972

Professional Career:

Fellow of St Cross College Professor and Head, Department of Public Health University of Oxford Oxford, England 2004-

Director National Center for HIV, STD, and TB Prevention Centers for Disease Control and Prevention Atlanta, GA 2001-2004

Director, Division of AIDS, STD and TB Laboratory Research, and Associate Director for HIV/AIDS, National Center for Infectious Diseases Centers for Disease Control and Prevention 1995-2001

Director, Division of HIV/AIDS Centers for Disease Control 1992-1995

Deputy Director for Science Division of HIV/AIDS Centers for Disease Control 1989-1992

2 Harold W. Jaffe, M.D.

Visiting Professor Chester Beatty Laboratories Institute of Cancer Research and Department of Medicine Hammersmith Hospital London, England 7/89-7/90

Chief Epidemiology Branch AIDS Program Centers for Disease Control 1983-1988

Epidemic Intelligence Service Officer Acquired Immunodeficiency Syndrome (AIDS) Activity Centers for Disease Control 1981-1983

Clinical Research Investigator Venereal Disease Control Division Centers for Disease Control 1980-1981

Fellow in Infectious Diseases University of Chicago Chicago, Illinois 1977-1980

Clinical Research Investigator Venereal Disease Control Division Centers for Disease Control 1974-1977

Resident in Medicine UCLA Hospital Los Angeles, California 1972-1974

Intern in Medicine UCLA Hospital Los Angeles, California 1971-1972

Appointments:

Assistant Surgeon General (Retired) U. S. Public Health Service

3 Harold W. Jaffe, M.D.

Clinical Assistant Professor of Medicine Emory University School of Medicine Atlanta, GA

Member, Institute of Medicine The National Academies USA

Fellow, Faculty of Public Health Royal Colleges of Physicians of the United Kingdom

Honorary Consultant in Epidemiology (Infectious Diseases) Oxford Radcliffe Hospitals NHS Trust

Committees:

Member, Program Committee, National Conference on Retroviruses and Opportunistic Infections, USA

Member, Life Sciences Committee, Health Protection Agency, UK

Editorial:

Member, Editorial Board, Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology

Member, Editorial Board, AIDS

Supervision of Students awarded DPhil degree

1. Nora Mutalima. Infections and childhood cancer in Malawi (2007)

2. Nathan Grills. “Believing” in HIV: The Effect of Faith on the Response of Christian Faith Based Organisations to HIV in India. (2008)

3. Mike April. “Human Immunodeficiency Virus Testing and Linkage-to-Care in South Africa: Epidemiological and Economic Evaluation of Expansion” (2008)

4 Harold W. Jaffe, M.D.

PUBLICATIONS

1. Yorra FH, Oblath R, Jaffe HW, Simmons DH, Levy SE. Massive thrombosis associated with use of the Swan-Ganz catheter. Chest 1974;65:682-684.

2. Jaffe HW. The laboratory diagnosis of syphilis. New concepts. Ann Intern Med 1975;83:846-850.

3. Kaufman RE, Johnson RE, Jaffe HW, Thornsberry C, Reynolds GH, Wiesner PJ. National gonorrhea therapy monitoring study. Treatment results. N Engl J Med 1976;294:1-4.

4. Jaffe HW, Biddle JW, Thornsberry C, Johnson RE, Kaufnan RE, Reynolds GH, Wiesner PJ. National gonorrhea therapy monitoring study. In vitro antibiotic susceptibility and its correlation with treatment results. N Engl J Med 1976;294:5-9.

5. Jaffe HW, Reynolds GH, Wiesner PJ. National gonorrhea therapy monitoring study. Adverse drug reactions. J Am Vener Dis Assoc 1976;3:29-31.

6. Jaffe HW. Treatment of latent syphilis. J Am Vener Dis Assoc 1976;3:143-145.

7. Balows A, Feeley JC, Jaffe HW. Laboratory diagnosis of treponematoses (with emphasis on syphilis). In: Johnson RD, ed. The Biology of Parasitic Spirochetes. New York: Academic Press, 1976:201-208.

8. Elliott WE, Reynolds GH, Thornsberry C, Kellogg DS, Jaffe HW, Brown ST, Armstrong J, Rein MF. Treatment of gonorrhea with trimethoprim-sulfamethoxazole. J Infect Dis 1977;135:939-943.

9. Thornsberry C, Jaffe HW, Brown ST, Edwards T, Biddle JW, Thompson SE. Spectinomycin-resistant Neisseria gonorrhoeae. JAMA 1977;237:2405-2406.

10. Jaffe HW, Zaidi AA, Thornsberry C, Reynolds GH, Wiesner PJ. Trends and seasonality of antibiotic resistance of Neisseria gonorrhoeae. J Infect Dis 1977;136:684-688.

11. Jaffe HW, Larsen SA, Peters M, Franco Jove D, Lopez B, Schroeter AL. Tests for treponemal antibody in CSF. Arch Intern Med 1978;138:252-255.

5 Harold W. Jaffe, M.D.

12. Jaffe HW, Larsen SA, Jones OG, Dans PE. Hemagglutination tests for syphilis antibody. Am J Clin Pathol 1978;70:230-233.

13. Thornsberry C, Jaffe HW, Reynolds GH, Zaidi AA, Wiesner PJ. Patient variables associated with penicillin resistance in Neisseria gonorrhoeae. Antimicrob Agents Chemother 1978;14:327-330.

14. Brown ST, Jaffe HW, Zaidi AA, Filker R, Herrmann KL, Lyerla HC, Franco Jove D, Budell JW. Sensitivity and specificity of diagnostic tests for genital infection with Herpesvirus hominis. Sex Transm Dis 1979;6:10-13.

15. Jaffe HW, Schroeter AL, Reynolds GH, Zaidi AA, Martin JE Jr, Thayer JD. Pharmacokinetic determinants of penicillin cure of gonococcal urethritis. Antimicrob Agents Chemother 1979;15:587-591.

16. Jaffe HW, Rice DT, Voigt R, Fowler J, St. John RK. Selective mass treatment in a venereal disease control program. Am J Public Health 1979;69:1181-1182.

17. Jaffe HW, Sweeney HM, Nathan C, Weinstein RA, Kabins SA, Cohen S. Identity and interspecific transfer of gentamicin-resistance plasmids in Staphylococcus aureus and Staphylococcus epidermidis. J Infect Dis 1980;141:738-747.18.

18. Jaffe HW, Biddle JW, Johnson SR, Wiesner PJ. Infections due to penicillinase-producing Neisseria gonorrhoeae in the United States: 1976-1980. J Infect Dis 1981;144:191-197 (CDC News).

19. Ashford WA, Potts DW, Adams HJU, English JC, Johnson SR, Biddle JW, Thornsberry C, Jaffe HW. Spectinomycin-resistant penicillinase-producing Neisseria gonorrhoeae. Lancet 1981;2:1035-1037.

20. Weinstein RA, Kabins SA, Nathan C, Sweeney HM, Jaffe HW, Cohen S. Gentamicin-resistant staphylococci as hospital flora: Epidemiology and resistance plasmids. J Infect Dis 1982;145:374-382.

21. Jaffe HW, Sweeney HM, Weinstein RA, Kabins SA, Nathan C, Cohen S. Structural and phenotypic varieties of gentamicin-resistance plasmids in hospital strains of Staphylococcus aureus and coagulase-negative staphylococci. Antimicrob Agents Chemother 1982;21:773-779.

22. Centers for Disease Control Task Force on Kaposi's Sarcoma and Opportunistic Infections. Epidemiologic aspects of the current outbreak of Kaposi's sarcoma and opportunistic infections. N Engl J Med 1982;306:248-252.

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23. Jaffe HW, Kraus SJ, Edwards TA, Weinberger SS, Zubrzycki L. Gonorrhea diagnosis using a genetic transformation test on mailed clinical specimens. J Infect Dis 1982;146:275-279.

24. Jaffe HW. Nongonococcal urethritis: Treatment of men and their sexual partners. Rev Infect Dis 1982;4 (suppl):5772-5777.

25. Jaffe HW, Kabins SA. Cerebrospinal fluid examination in patients with syphilis. Rev Infect Dis 1982;4 (suppl):5842-S847.

26. Jaffe HW, Choi K, Thomas PA, et al. National case-control study of Kaposi's sarcoma and Pneumocystis carinii in homosexual men: Part 1, epidemiologic results. Ann Intern Med 1983;99:145-151.

27. Jaffe HW, Bregman DJ, Selik RM. Acquired immune deficiency syndrome in the United States: The first 1,000 cases. J Infect Dis 1983;148:339-345.

28. Auerbach DM, Darrow WW, Jaffe HW, Curran JW. A cluster of cases of the acquired immune deficiency syndrome: Patients linked by sexual contact. Am J Med 1984;76:487-492.

29. Guinan ME, Thomas PA, Pinsky PF, Goodrich JT, Selik RM, Jaffe HW, Haverkos HW, Noble G, Curran JW. Heterosexual and homosexual patients with the acquired immunodeficiency syndrome. A comparison of surveillance, interview, and laboratory data. Ann Intern Med 1984;100:213-218.

30. Curran JW, Lawrence DN, Jaffe HW, et al. Acquired immunodeficiency syndrome (AIDS) associated with transfusions. N Engl J Med 1984;310:69-75.

31. Jaffe HW, Francis DP, McLane MF, et al. Transfusion-associated AIDS: Serologic evidence of human t-cell leukemia virus infection of donors. Science 1984;223:1309-1312.

32. Feorino PM, Kalyanaraman VS, Haverkos HW, Cabradilla CD, Warfield DT, Jaffe HW, Harrison AK, Gottlieb MS, Goldfinger D, Chermann J-C, Barre-Sinoussi F, Spira TJ, McDougal JS, Curran JW, Montagnier L, Murphy FA, Francis DP. Lymphadenopathy associated virus infection of a blood donor-recipient pair with acquired immunodeflciency syndrome. Science 1984;225:69-72.

33. Kalyanaraman VS, Cabradilla CD, Getchell JP, Narayanan R, Braff EH, Chermann J-C, Barre-Sinoussi F, Montagnier L, Spira TJ, Kaplan J, Fishbein D, Jaffe HW, Curran JW, Francis DP. Antibodies to the core proteins of lymphadenopathy-associated virus (LAV) in patients with AIDS. Science 1984;225:321-323.

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34. Thomas PA, Jaffe HW, Spira TJ, Reiss R, Guerrero IC, Auerbach D. Unexplained immunodeficiency in children. JAMA 1984;252:639-644.

35. Chamberland ME, Castro KG, Haverkos HW, Miller BI, Thomas PA, Reiss R, Walker J, Spira TJ, Jaffe HW, Curran JW. Acquired immunodeficiency syndrome in the United States: An analysis of cases outside high incidence groups. Ann Intern Med 1984;101:617-623.

36. Jaffe HW. Management of the Reactive Serology. In: Holmes KK, Wiesner PJ, Mardh PA, Sparling PF, eds. Sexually Transmitted Diseases. New York: McGraw Hill, 1984:313-318.

37. Curran JW, Gold J, Jaffe HW. The acquired immunodeficiency syndrome (AIDS). In: Holmes KK, Wiesner PJ, Mardh PA, Sparling PF, eds. Sexually Transmitted Diseases. New York: McGraw Hill, 1984:691-706.

38. Jaffe HW, Feorino PM, Darrow WW, et al. Persistent infection with human T-lymphotropic virus type III/1ymphadenopathy-associated virus in apparently healthy homosexual men. Ann Intern Med 1985;102:627-628.

39. Feorino PM, Jaffe HW, Palmer E, et al. Transfusion-associated acquired immunodeficiency syndrome: Evidence for persistent infection in blood donors. N Engl J Med 1985;312:1293-1296.

40. Nicholson JKA, McDougal JS, Jaffe HW, et al. Exposure to human T lymphotropic virus type III/lymphadenopathy-associated virus and immunologic abnormalities in asymptomatic homosexual men. Ann Intern Med 1985;103:37-42.

41. Jaffe HW, Darrow WW, Echenberg DF, et al. The acquired immunodeflciency syndrome in a cohort of homosexual men. A six-year follow-up study. Ann Intern Med 1985;103:210-214.

42. Jaffe HW, Sarngadharan MG, DeVico AL, et al. Infection with HTLV-III/LAV and transfusion-associated acquired immunodeficiency syndrome. Serologic evidence of an association. JAMA 1985;254:770-773.

43. McDougal JS, Hubbard M, Nicholson JKA, Jones BM, Holman RC, Roberts J, Fishbein DB, Jaffe HW, Kaplan JE, Spira TJ, Evatt BL. Immune complexes in the acquired immunodeficiency syndrome (AIDS): Relationship to disease manifestation, risk group, and immunologic defect. J Clin Immunol 1985;5:l30-l38.

44. McDougal JS, Jaffe HW, Cabridilla CD, et al. Screening tests for blood donors presumed to have transmitted the acquired immunodeficiency syndrome. Blood 1985;65:772-775.

45. Curran JW, Morgan WM, Hardy AM, Jaffe HW, Darrow WW, Dowdle WR. The epidemiology of AIDS: Current status and future prospects. Science 1985;229:1352-1357.

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46. Peterman TA, Jaffe HW, Feorino PM, et al. Transfusion-associated acquired immunodeficiency syndrome in the United States. JAMA 1985;254:2913-2917.

47. Jaffe HW, Hardy AM, Morgan WM, Darrow WW. The acquired immunodeficiency syndrome in gay men. Ann Intern Med 1985;103:662-664.

48. Francis DP, Jaffe HW, Fultz PN, Getchell JP, McDougal JS, Feorino PM. The natural history of infection with the lymphadenopathy-associated virus/human T-lymphotropic virus type III. Ann Intern Med 1985;103:719-722.

49. Curran JW, Morgan WM, Starcher ET, Hardy AM, Jaffe HW. Epidemiological trends of AIDS in the United States. Cancer Research 1985;45:4602S-4604S.

50. Darrow WW, Jaffe HW, Thomas PA, et al. Sex of interviewer, place of interview, and responses of homosexual men to sensitive questions. Arch Sex Behav 1986;15:79-88.

51. Nicholson JKA, Echenberg DF, Jones BM, Jaffe HW, Feorino PM, McDougal JS. T-cytotoxic/supressor cell phenotypes in a group of asymptomatic homosexual men with and without exposure to HTLV-III/LAV. Clin Immunol and Immunopathol 1986;40:505-514.

52. Lifson AR, Castro KG, McCray E, Jaffe HW. National surveillance of AIDS in health care workers. JAMA 1986;256:3231-3234.

53. Jaffe HW. The acquired immunodeficiency syndrome epidemic: Issues for health care professionals (Ninth Annual National Foundation for Infectious Diseases Lecture). Am J Infect Control 1986;55:272-279.

54. Rabkin CS, Thomas PA, Jaffe HW, Schultz S. Prevalence of antibody to HTLV-III/LAV in a population attending a sexually transmitted diseases clinic. Sex Transm Dis 1987;14:48-51.

55. Jaffe HW, Hardy AM, Bush TJ, Selik RM, Morgan WM. AIDS within population groups in the United States. Ann Inst Pasteur/Virol 1987;138:75-78.

56. Darrow WW, Echenberg DF, Jaffe HW, et al. Risk factors for human immunodeficiency virus (HIV) infections in homosexual men. Am J Public Health 1987;77:479-483.

57. Srinivasan A, York D, Ranganathan P, Ferguson R, Butler D, Feorino P, Kalyanaraman V, Jaffe H, Curran J, Anand R. Transfusion-associated AIDS: Donor-recipient human immunodeficiency virus exhibits genetic heterogeneity. Blood 1987;69:1766-1770.

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58. McDougal JS, Kennedy MS, Nicholson JKA, Spira TJ, Jaffe HW, Kaplan JE, Fishbein DB, O'Malley P, Aloisio CH, Black CM, Hubbard M, Reimer CB. Antibody response to human immunodeficiency virus in homosexual men. J. Clin Invest 1987;80:316-324.

59. Rogers MF, Thomas PA, Starcher ET, Noa MC, Bush TJ, Jaffe HW. Acquired immunodeficiency syndrome in children: Report of the Centers for Disease Control national surveillance, 1982 to 1985. Pediatrics 1987:79:1008-1014.

60. Anand R, Moore J, Jaffe H, Feorino P, Weinstein R, Curran J, Srinivasan A. DNA and protein heterogeneity in serial isolates of human immunodeficiency virus (HIV-1): Indication of change in vivo Microbios 1987;52:191-201.

61. Peterman TA, Stoneburner RL, Allen JR, Jaffe HW, Curran JW. Risk of HIV transmission from heterosexual adults with transfusion-associated infections. JAMA 1988;259:55-58.

62. Castro KG, Lieb S, Jaffe HW, Narkunas JP, Calisher CH, Bush T, Witte JJ. The Belle Glade Field-Study Group. Transmission of HIV in Belle Glade, Florida: Lessons for other communities in the United States. Science 1988;239:l93-l97.

63. Curran JW, Jaffe HW, Hardy AM, Morgan WM, Selik R, Dondero TJ. The epidemiology of HIV infection and AIDS in the United States. Science 1988;239:610-616.

64. Castro KG, Lifson AR, White CR, Bush TJ, Chamberland ME, Lekatsas AM, Jaffe HW. Investigations of AIDS patients with no previously identified risk factors. JAMA 1988;259:l338-l342.

65. Jaffe HW, Lifson AR. Acquisition and transmission of HIV. Infect Dis Clin N Amer 1988;2:299-306.

66. Ward JW, Holmberg SD, Allen JR, Cohn DL, Critchley SE, Kleinman SH, Lenes BA, Ravenholt O, Davis JR, Quinn MG, Jaffe HW. Transmission of human immunodeficiency virus (HIV) by blood transfusions screened as negative for HIV antibody. N Engl J Med 1988;3l8:473-478.

67. Hughes JM, Garner JS, Marcus R, Jaffe HW. AIDS: Epidemiologic lessons from the health-care setting. J Hosp Infect 1988;ll(suppl. A):209-2l7.

68. Lieb S, Castro KG, Calisher CH, Withum DG, Buff EE, Schable CA, Monath TP, Jaffe HW, Witte JJ. Human immunodeficiency virus infection in a rural community. J Fla Med Assoc 1988;75:301-304.

69. Lifson AR, Rutherford GW, Jaffe HW. The natural history of human immunodeficiency virus infection. J Infect Dis (AIDS Commentary) 1988;l58:l360-l367.

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70. Byers RH Jr, Morgan WM, Darrow WW, Doll L, Jaffe HW, Rutherford G, Hessol N, O'Malley PM. Estimating AIDS infection rates in the San Francisco Cohort. AIDS 1988;2:207-210.

71. Jaffe HW, Lifson AR. Acquisition and transmission of HIV. In: MA Sande and PA Volberding, eds. The Medical Management of AIDS. Philadelphia: W.B. Saunders Co., 1988:19-27.

72. Holmberg SD, Horsburgh CR Jr, Ward JW, Jaffe HW. Biologic factors in the sexual transmission of human immunodeficiency virus. J Infect Dis (AIDS Commentary) 1989;l60:ll6-l25.

73. Horsburgh CR Jr, Ou CY, Jason J, Holmberg SD, Longini IM Jr, Schable C, Mayer KH, Lifson AR, Schochetman G, Ward JW, Rutherford GW, Evatt BL, Seage GR, Jaffe HW. Duration of human immunodeficiency virus infection before detection of antibody. Lancet 1989;2:637-640.

74. Hessol NA, Lifson AR, O'Malley PM, Doll LS, Jaffe HW, Rutherford G. Prevalence, incidence, and progression of human immunodeficiency virus in homosexual and bisexual men in hepatitis B vaccine trials, 1978-1988. Am J Epidemiol 1989;130:1167-1175.

75. Winkelstein W Jr, Padian NS, Rutherford G, Jaffe HW. Homosexual men. In: RA Kaslow and DP Francis, eds. The Epidemiology of AIDS. New York. Oxford University Press, 1989;117-135.

76. Seage GR III, Horsburgh CR Jr, Hardy AM, Mayer KH, Barry MA Groopman JE, Jaffe HW, Lamb GA. Increased suppressor T cells in probable transmitters of human immunodeficiency virus infection. Am J Public Health 1989;79:1638-1643.

77. Chiasson MA, Stoneburner RL, Lifson AR, Hildebrandt DS, Ewing WE, Schultz S, Jaffe HW. Risk factors for human immunodeficiency virus type 1 (HIV-l) infection in patients at a sexually transmitted disease clinic in New York City. Am J Epidemiol 1990;131:208-220.

78. Lifson AR, Darrow WW, Hessol NA, O'Malley PM, Barnhart JL, Jaffe HW, Rutherford GW. Kaposi's sarcoma in a cohort of homosexual and bisexual men: Epidemiology and analysis for cofactors. Am J Epidemiol 1990;131:221-231.

79. Beral V, Peterman TA, Berkelman RL, Jaffe HW. Kaposi's sarcoma among persons with AIDS: A sexually transmitted infection? Lancet 1990;335:123-128.

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80. Rosenblum LS, Hadler SC, Castro KG, Lieb S, Jaffe HW, the Belle Glade Study Group. Heterosexual transmission of hepatitis B virus in Belle Glade, Florida. J Infect Dis 1990;161:407-411.

81. Horsburgh CR Jr., Ou C-Y, Jason J, Holmberg SD, Lifson AR, Moore JL, Ward JW, Seage GR, Mayer KH, Evatt BL, Schochetman G, Jaffe HW. Concordance of polymerase chain reaction with human immunodeficiency virus antibody detection. J Infect Dis 1990;162:542-545.

82. Jaffe HW. AIDS: Epidemiologic Features. J Am Acad Dermatol 1990;22:1167-1171.

83. Handsfield HH, Jaffe HW. Epidemiology of AIDS and HIV infection in the United States. In: Holmes KK, Core L, Collier AC, Handsfield HH, eds. AIDS Dx/Rx. New York: McGraw-HilI, 1990:1-15.

84. Weiss RA, Jaffe HW. Duesberg, HIV and AIDS [commentary]. Nature 1990;345:659-660.

85. Jaffe HW. What doctors want to tell judges about AIDS. The Judges Journal 1990;29:8-13, 61-64.

86. Rutherford GW, Lifson AR, Hessol NA, Darrow WW, O'Malley PM, Buchbinder SP, Barnhart JL, Bodecker TW, Cannon L, Doll LS, Holmberg SD, Harrison JS, Rogers MF, Werdegar D, Jaffe HW. Course of HIV-1 infection in a cohort of homosexual and bisexual men: an 11 year follow up study. Br Med J 1990;301:1183-1188.

87. Beral V, Bull D, Jaffe H, Evans B, Gill N, Tillett H, Swerdlow AJ. Is risk of Kaposi's sarcoma in AIDS patients in Britain increased if sexual partners came from the United States or Africa? Br Med J. 1991;302:624-625.

88. Beral V, Peterman T, Berkelman R, Jaffe H. AIDS-associated non-Hodgkins lymphoma. Lancet 1991;337:805-809.

89. Chiasson MA, Stoneburner RL, Hildebrandt DS, Ewing WE, Telzak EE, Jaffe HW. Heterosexual transmission of HIV-1 associated with the use of smokable freebase cocaine (crack). AIDS 1991;5:1121-1126.

90. Peterman TA, Jaffe HW, Friedman-Kien AE, Weiss RA. The Aetiology of Kaposi's sarcoma. In: V Beral, HW Jaffe, and RA Weiss, eds. Cancer, HIV and AIDS. New York: Cold Spring Harbor Laboratory Press, 1991:23-37.

91. Chamberland ME, Conley LJ, Bush TJ, Ciesielski CA, Hammett TA, Jaffe HW. Health care workers with AIDS. National surveillance update. JAMA 1991;266:3459-3462.

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92. Beral V, Bull D, Darby S, Weller I, Carne C. Beecham M, Jaffe H. Risk of Kaposi's sarcoma and sexual practices associated with faecal contact in homosexual or bisexual men with AIDS. Lancet 1992;339:632-635.

93. Ciesielski C, Marianos D, Ou C-Y, Dumbaugh R, Witte J, Berkelman R, Gooch B, Myers G, Luo C-C, Schochetman G, Howell J, Lasch A, Bell K, Economu N, Scott B, Furman L, Curran J, Jaffe H. Transmission of human immunodeficiency virus in a dental practice. Ann Intern Med 1992;116(10):798-805.

94. Ou C-Y, Ciesielski CA, Myers G, Bandea CI, Luo C-C, Korber BTM, Mullins JI, Schochetman G, Berkelman RL, Economu AN, Witte JJ, Furman LJ, Satten GA, MacIness KA, Curran JW, Jaffe HW. Laboratory Investigations Group, Epidemiologic Investigation Group. Molecular epidemiology of HIV transmission in a dental practice. Science 1992;256:1165-1171.

95. O'Brien TR, Shaffer N, Jaffe HW. Acquisition and transmission of HIV. In: MA Sande and PA Volberding, eds. The Medical Management of AIDS. Third Edition, Philadelphia: W.B. Saunders Co., 1992:3-17.

96. Smith DK, Neal JJ, Holmberg SD. CDC Idiopathic CD4+ T-Lymphocytopenia Task Force. Unexplained opportunistic infections and CD4+ T-lymphocytopenia without HIV infection. N Engl J Med 1993;328:373-379.

97. Gooch B, Marianos D, Ciesielski C, Dumbaugh R, Lasch A, Jaffe H, Bond W, Lockwood S, Cleveland J. Lack of evidence of patient-to-patient transmission of HIV in a dental practice. JADA 1993;124:38-44.

98. Peterman TA, Jaffe HW, Beral V. Epidemiologic clues to the etiology of Kaposi's sarcoma. AIDS 1993;7:605-611.

99. Telzak EE, Chiasson MA, Bevier PJ, Stoneburner RL, Castro KG, Jaffe HW. HIV-1 seroconversion in patients with and without genital ulcer disease. A Prospective Study. Ann Intern Med 1993;119:1181-1186.

100. Schable C, Zekeng L, Pau C-P, Hu D, Kaptue L, Gurtler L, Dondero T, Tsague J-M, Schochetman G, Jaffe H, George R. Sensitivity of United States HIV antibody tests for detection of HIV-1 group O infections. Lancet 1994;344:1333-4

101. Jaffe HW, McCurdy JM, Kalish ML, et al. Lack of HIV transmission in the practice of a dentist with AIDS. Ann Intern Med 1994;121:855-9.

102. Ciesielski CA, Marianos DW, Schochetman G, Witte JJ, Jaffe HW. The 1990 Florida dental investigation. The Press and the Science (Perspective). Ann Intern Med 1994;121:886-8.

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103. Rogers MF, Jaffe HW. Reducing the risk of maternal-infant transmission of HIV: A door is opened (Editorial). N Engl J Med 1994;331:1222-3.

104. Buehler JW, Petersen LR, Jaffe HW. Current trends in the epidemiology of HIV/AIDS. In: MA Sande and PA Volberding, eds. The medical management of AIDS. Fourth Edition, Philadelphia: W.B. Saunders Co. 1995:3-21.

105. Schable C, Zekeng L, Pau C-P, Hu D, Kaptue L, Gurtler L, Dondero T, Tsague J-M, Schochetman G, Jaffe H, George JR. Sensitivity of United States HIV antibody tests for detection of HIV-1 group O infections. Lancet l994;344:1333-4.

106. Robert LM, Chamberland ME, Cleveland JL, Marcus R, Gooch BF, Srivastava PU, Culver DH, Jaffe HW, Marianos DW, Panlilio AL, Bell DM. Investigations of patients of health care workers infected with HIV. The Centers for Disease Control and Prevention Database. Ann Intern Med l995;122:653-7.

107. Kaplan JE, Masur H, Jaffe HW, Holmes KK. Reducing the impact of opportunistic infections in patients with HIV infection. New guidelines. (Editorial) JAMA 1995;274: 347-8.

108. Kaplan JE, Masur H, Holmes KK, Wilfert CM, Sperling R, Baker SA, Trapnell CB, Freedberg KA, Cotton D, Powderly WG, Jaffe HW, and the USPHS/IDSA Prevention of Opportunistic Infections Working Group. USPHS/IDSA guidelines for the prevention of opportunistic infections in persons infected with human immunodeficiency virus: An overview. Clin Infect Dis 1995; 21 (Suppl 1):S12-31.

109. Hu DJ, Dondero TJ, Rayfield MA, George JR, Schochetman G, Jaffe HW, Luo C-C, Kalish ML, Weinger BG, Pau C-P, Schable CA, Curran JW. The emerging genetic diversity of HIV. The importance of global surveillance for diagnostics, research, and prevention. JAMA 1996;275:210-5.

110. Chang Y, Ziegler J, Wabinga H, Katangole-Mbidde E, Boshoff C, Schultz T, Whitby D, Maddalena D, Jaffe HW, Weiss RA, the Uganda Kaposi’s Sarcoma Study Group, Moore PS. Kaposi’s sarcoma-associated herpevirus and Kaposi’s sarcoma in Africa. Arch Intern Med 1996;156:202-4.

111. Moore PS, Kingsley LA, Holmberg SD, Spira T, Gupta P, Hoover DR, Parry JR, Conley LJ, Jaffe HW, Chang Y. Kaposi’s sarcoma-associated herpesvirus infection prior to the onset of Kaposi’s sarcoma. AIDS 1996;10:175-80.

112. Kaplan JE, Hu DL, Holmes KK, Jaffe HW, Masur H, DeCock KM. Preventing opportunistic infections in human immunodeficiency virus-infected persons:

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Implications for the developing world. Am J Trop Med Hyg (Editorial) 1996;55:1-11

113. Ward JW, Petersen LR, Jaffe HW. Current trends in the epidemiology of HIV/AIDS. In MA Sande and PA Volberding, eds. The medical management of AIDS. Fifth Edition. Philadelphia: W.B. Saunders Co. 1997:3-16.

114. Expert Group of the Joint United Nations Programme on HIV/AIDS. Implications of HIV variability for transmission: Scientific and Policy Issues. AIDS 1997;11:UNAIDS 1- UNAIDS 15.

115. Kaplan JE, Masur H, Jaffe HW, Holmes KK. Preventing opportunistic infections in persons infected with HIV: 1997 guidelines. JAMA (Editorial) 1997;278;337-8.

116. Jaffe HW, Frankel SS. Kaposi’s sarcoma and human herpesvirus 8. In: CR Horsburgh, Jr. and AM Nelson, eds. Pathology of Emerging Infections. Washington, DC: ASM Press. 1997:107-17.

117. Ziegler JL, Newton R, Katongole-Mbidde E, Mbulataiye S, DeCock K, Wabinga H, Mugerwa J, Katabira E, Jaffe H, Parkin DM, Reeves G, Weiss R, Beral V. Risk factors for Kaposi’s sarcoma in HIV-positive subjects in Uganda. AIDS 1997;11:1619-26.

118. Jaffe HW, Schochetman G. Group O human immunodeficiency virus-1 infections. Infect Dis Clinics North America 1998;12:39-46.

119. Spira TJ, Jaffe HW. Human herpesvirus 8 and Kaposi’s sarcoma. In WM Scheld, WA Craig, and JM Hughes (ed.) Emerging Infections 2. ASM Press, Washington, DC, 1998:81- 104.

120. Tsang SX, Switzer WM, Shanmugam V, Johnson J, Goldsmith C, Wright A, Fadly A, Thea D, Jaffe H, Folks TM, Heneine W. Evidence of avian leukosis virus subgroup E and endogenous avian virus in measles and mumps vaccines derived from chicken cells: Investigation of transmission to vaccine recipients. J Virol 1999;73:5843-51.

121. Jaffe HW, Pellett PE. Human herpesvirus 8 and Kaposi’s sarcoma - some answers, more questions. N Engl J Med (Editorial) 1999;340:1912-3.

122. Jones JL, Hanson DL, Dworkin MS, Ward JW, Jaffe HW. Adult/Adolescent Spectrum of HIV Disease Project Group. Effect of antiretroviral therapy on recent trends in selected cancers among HIV-infected persons. J Acquir Immune Defic Syndr 1999;21(Suppl 1): S117.

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123. Jones JL, DeCock KM, Jaffe HW. Current Trends in the Epidemiology of HIV/AIDS. In MA Sande and PA Volberding (ed). The Medical Management of AIDS. 6th Edition. W.B. Saunders Company, Philadelphia, 1999:3-22

124. Collaborative Group on AIDS Incubation and HIV Survival including CASCADE EU Concerted Action (H. Jaffe, member). Time from HIV-1 seroconversion and death before widespread use of highly-active antiretroviral therapy: A collaborative re-analysis. Lancet 2000;355:1131-7.

125. Gnann JW Jr., Pellett PE, Jaffe HW. Human herpesvirus 8 (HHV-8) and Kaposi’s sarcoma in persons infected with human immunodeficiency virus. Clin Infect Dis 2000;30:S72-6.

126. Jones JL, Hanson DL, Dworkin MS, Jaffe HW. Adult/Adolescent Spectrum of Disease Project Group. Incidence and trends in Kaposi’s sarcoma in the era of effective antiretroviral therapy. J Acquir Immune Defic Syndr 2000;24:270-4

127. Otten RA, Smith DK, Adams DR, Pullium JK, Jackson E, Kim CN, Jaffe H, Janssen R, Butera S, Folks TM. Efficacy of postexposure prophylaxis after intravaginal exposure of pig-tailed macaques to a human-derived retrovirus (human immunodeficiency virus type 2). J Virol 2000;74:9771-5.

128. International Collaboration on HIV and Cancer (H Jaffe, Chairman, Steering Committee). Highly active antiretroviral therapy and incidence of cancer in human immunodeficiency virus- infected adults. J Natl Cancer Inst 2000;92:1823-30. 129. Newton R, Ziegler J, Ateenyi-Agaba C, Boursarghin L, Casabonne D, Beral V, Mbidde E, Carpenter L, Reeves G, Parkin DM, Wabinga H, Mbulaiteye S, Jaffe H, Bouboulia D, Boshoff C, Touze A, Coursaget P, Uganda Kaposi’s Sarcoma Study Group. The epidemiology of conjunctival squamous cell carcinoma in Uganda. Br J Cancer 2002;87:301- 8.

130. Newton R, Ziegler J, Beral V, Mbidde E, Carpenter L, Wabinga H, Mbulaiteye S, Appleby P, Reeves, G, Jaffe H. A case-control study of human immunodeficiency virus infection and cancer in adults and children residing in Kampala, Uganda. Int J Cancer 2001; 92:622-7.

131. Castro KG, Jaffe HW. Rationale and methods for the National Tuberculosis Genotyping and Surveillance Network. Emerg Infect Dis 2002;11:1188-91.

132. Cannon MJ, Dollard SC, Black JB, Edlin BR, Hannah C, Hogan SE, Patel MM, Jaffe HW, Offermann MK, Spira TJ, Pellett PE, Gunthel CJ. Risk factors for Kaposi’s sarcoma in men seropositive for both human herpesvirus 8 and human immunodeficiency virus. AIDS 2003 ; 17:215-22

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133. Robbins KE, Lemey P, Pybus OG, Jaffe HW, Youngpairoj AS, Brown TM, Salemi M, Vandamme A-M, Kalish,MK. U.S. HIV-1 epidemic: Estimation of date of origin,population history and characterization of early strains. J Virol. 2003;77: 6359-66.

134. Newton R, Ziegler J, Bourboulia D, Casabonne D, Beral V, Mbidde E, Carpenter L, Reeves G, Parkin DM, Wabinga H, Mbulaiteye S, Jaffe H, Weiss R, Boshoff C. The sero- epidemiology of Kaposi’s sarcoma-associated herpesvirus (KSHV/HHV-8) in adults with cancer in Uganda. Int J Cancer 2003;103:226-32.

135. Ziegler J, Newton R, Bourboulia D, Casabonne D, Beral V, Mbidde E, Carpenter L, Reeves G, Parkin DM, Wabinga H, Mbulaiteye S, Jaffe H, Weiss R, Boshoff C. Risk factors for Kaposi’s sarcoma: A case-control study of HIV-seronegative people in Uganda. Int J Cancer 2003;103:233-40.

136. Newton R, Ziegler J, Bourboulia D, Casabonne D, Beral V, Mbidde E, Carpenter L, Parkin DM, Wabinga H, Mbulaiteye S, Jaffe H, the Uganda Kaposi's Sarcoma Study Group, Weiss R, Boshoff C. Infection with Kaposi's sarcoma-associated herpesvirus (KSHV) and human immunodeficiency virus (HIV) in relation to the risk and clinical presentation of Kaposi's sarcoma in Uganda. Brit J Cancer, 2003; 89: 502-4.

137. Kalish ML, Robbins KE, Pieniazek D, Schaefer A, Nzilambi N, Quinn TC, St. Louis ME, Youngpairoj AS, Phillips J, Jaffe HW, Folks TM. Recombinant viruses and early global HIV-1 epidemic. Emerg Infect Dis 2004;10:1227-34.

138. Laney AS, Dollard SC, Jaffe HW, Offerman MK, Spira TJ, Gunthel CJ, Pellet PE, Cannon MJ. Repeated measures study of human herpesvirus 8 (HHV-8) DNA and antibodies in men seropositive for both HHV-8 and HIV. AIDS 2004;18:1-8.

139. Jaffe HW. Whatever happened to the U.S. AIDS epidemic? Science 2004;305:1243-4.

140. Newton R, Bousarghin L, Ziegler J, Casabonne D, Beral V, Mbidde E, Carpenter L, Parkin DM, Wabinga H, Mbulaiteye S, Jaffe H, Touzé A, Coursaget A and the Uganda Kaposi's Sarcoma Study Group. Human Papillomaviruses and Cancer in Uganda, Eur J Cancer Prev, 2004; 13: 113-8.

141. Jaffe HW. The early days of AIDS in the United States: A personal perspective. Curare 2005;28:132-6.

142. Newton R, Ribeiro T, Alvarez E, Ziegler J, Casabonne D, Carpenter L, Beral V, Mbidde E, Parkin DM, Wabinga H, Mbulaiteye S, Jaffe H, Touze A, Coursaget P, Uganda Kaposi’s Sarcoma Study Group. BK virus and cancer in Uganda. European Journal of Cancer 143. Prevention. 2006;15:285-9.

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143. Newton R, Ziegler JL, Casabonne D, Carpenter L, Gold BD,Owens M, Beral V, Mbidde E, Parkin M, Wabinga H, Mbulaiteye S, Jaffe H, Uganda Kaposi's Sarcoma Study Group. Helicobacter pylori and cancer among adults in Uganda. Infectious Agents and Cancer 2006;1:5.

144. Bulterys M, Smith D, Chao A, Jaffe H. Hormonal contraception and incident HIV-1 infection: New insight and continuing challenges. AIDS 2007;21:97-9.

145. Hammill M, Burgoine K, Farrell F, Hemelaar J, Patel G, Welchew DE, Jaffe HW. Time to move towards opt-out testing for HIV in the UK. BMJ 2007;334:1352-4.

146. Paxton LA, Hope T, Jaffe HW. Pre-exposure prophylaxis for HIV infection: What if it works? Lancet 2007;370:89-93.

147. Franceschi S, Jaffe H. Cervical Cancer screening of women living with HIV infection: A must in the era of antiretroviral therapy. Clin Infect Dis 2007:45;510-3.

148. Jaffe HW, Valdiserri RO, DeCock KM. The Reemerging HIV/AIDS epidemic in men who have sex with men. JAMA 2007;298:2412-4.

149. Carpenter LM, Newton R, Casabonne D, Ziegler J, Mbulaiteye S, Mbidde E, Wabinga H, Jaffe H, Beral V. Antibodies against malaria and Epstein Barr virus in childhood Burkitt lymphoma: a case-control study in Uganda. Int J Cancer 2008;122:1319-23.

150. MacDonald A, Humphreys J, Jaffe HW. Prevention of HIV transmission in the UK: What is the role of male circumcision? Sex Trans Infect 2008;84:158-160.

151. Mutalima N, Molyneux E, Jaffe H, Kamiza S, Borgstein E, Mkandawire N, Liomba G, Batumba M, Lagos D, Gratrix F, Boshoff C, Casabonne D, Carpenter LM, Newton R. Associations between Burkitt Lymphoma among Children in Malawi and Infection with HIV, EBV and Malaria: Results from a Case-Control Study. *PLoS ONE 2008;3(6):e2505.

152. Jaffe HW. Universal access to HIV/AIDS treatment. Promises and problems. JAMA 2008; 300:573-5.

153. Jaffe HW. The early days of the HIV-AIDS epidemic in the USA. Nature Immunology. 2008;9:1201-3.

154. Jaffe HW. Increasing knowledge of HIV infection status through opt-out testing. Journal of Bioethical Inquiry 2009;6:229-33.

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155. Smith AD, Tapsoba P, Peshu N, Sanders EJ, Jaffe HW. Invisible in the HIV/AIDS response – Men who have sex with men in sub-Saharan Africa. Lancet (in press)

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