Program Director/Principal Investigator (Last, First, Middle): .

BIOGRAPHICAL SKETCH Provide the following information for the Senior/key personnel and other significant contributors in the order listed on Form Page 2. Follow this format for each person. DO NOT EXCEED FOUR PAGES.

NAME POSITION TITLE Bentley, Margaret E. Carla Smith Chamblee Distinguished Professor of Global eRA COMMONS USER NAME (credential, e.g., agency login) Nutrition, Associate Dean for Global Health, Associate MARGARET_BENTLEY Director, Institute for Global Health & Infectious Diseases EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, include postdoctoral training and residency training if applicable.) DEGREE INSTITUTION AND LOCATION MM/YY FIELD OF STUDY (if applicable) Michigan State University, Lansing, MI B.A. 1976 Anthropology & Nutrition

University of Connecticut, Storrs, CT M.A. 1983 Anthropology

University of Connecticut, Storrs, CT. Ph.D. 1987 Anthropology

A. Personal Statement Dr. Bentley is a medical/nutritional anthropologist whose research focus is on women’s and infants’ nutrition, infant and young child feeding, HIV and breastfeeding, and community-based interventions for improving growth and development of young children. She has expertise in both qualitative and quantitative research methods and in the application of these for program development and evaluation. Bentley was PI of a recently completed NICHD/NIH five-year longitudinal study, Infant Care, Feeding, and Risk of Obesity, to examine the role of behavioral and environmental factors on infant health outcomes in low-income African-American mothers and infants in North Carolina. She was also PI of an NICHD/NIH 60 village, 600 mother-infant pair randomized clinical trial to improve growth and development of infants and young children in Andhra Pradesh, India, whose data are in analyses. She was PI of a Bill and Melinda Gates study that is analyzing nutrition and biomarker data of HIV-positive women enrolled in the BAN (Breastfeeding, Antiretroviral, and Nutrition) study in Malawi.

B. Positions and Honors

Positions and Employment 1985-86 UNICEF, South Asia Regional Office, Diarrhea Management Program, New Delhi, India 1986-87 Research Associate, Division of Human Nutrition, Department of International Health, School of Hygiene and Public Health, The Johns Hopkins University, Baltimore, MD 1987-89 Assistant Professor, Division of Human Nutrition, Department of International Health, School of Hygiene and Public Health, The Johns Hopkins University, Baltimore, MD 1989-90 Acting Division Director, Assistant Professor, Division of Human Nutrition, Department of International Health, School of Hygiene and Public Health, The Johns Hopkins University, Baltimore, MD 1990-92 Assistant Professor, Division of Human Nutrition, Department of International Health, School of Hygiene and Public Health, The Johns Hopkins University, Baltimore, MD 1992-93 Visiting Scholar, International Food Policy Research Institute, Washington, D.C. 1993-98 Associate Professor, Division of Human Nutrition, Department of International Health, School of Hygiene and Public Health, The Johns Hopkins University, Baltimore, MD 1998-03 Associate Professor (Tenured), Department of Nutrition, School of Public Health and Fellow, Carolina Population Center, University of North Carolina at Chapel Hill (UNC-CH)

PHS 398/2590 (Rev. 06/09) Page Biographical Sketch Format Page Program Director/Principal Investigator (Last, First, Middle): . 1998-03 Adjunct Associate Professor, Division of Human Nutrition, Department of International Health, The Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland 1999-02 Associate Chair, Department of Nutrition, School of Public Health, UNC-CH 2003- Professor, Department of Nutrition, School of Public Health, UNC-CH 2003- Associate Dean for Global Health, School of Public Health, UNC-CH 2007- Associate Director, Institute for Global Health and Infectious Diseases, UNC-CH 2010- Adjunct Professor, Department of Anthropology, University of North Carolina, UNC-CH 2012- Carla Smith Chamblee Distinguished Professor of Global Nutrition

Other Experience and Professional Memberships American Institute of Nutrition American Public Health Association American Anthropological Association Council on Nutritional Anthropology International Union of Anthropological and Ethnological Sciences Society for Applied Anthropology Society for International Nutrition Society for Medical Anthropology Society for Nutrition Education International Society for Research on Human Milk and Lactation

Honors 2012- Carla Smith Chamblee Distinguished Professor of Global Nutrition 2006- Ambassador, Paul G. Rogers Society for Global Health Research 2002- Fellow, Society for Applied Anthropology 2000- Member, Delta Omega Society

C. Selected Peer-reviewed Publications (in chronological order) 1. Doak, C. M.*, Adair, L. S., Bentley, M., Monteiro, C., & Popkin, B. M. (2005). The dual burden household and the nutrition transition paradox. International Journal of Obesity, 29(1), 129-136. 2. Thrasher, J. F.*, & Bentley, M. E. (2006). The meanings and context of smoking among mexican university students. Public Health Reports (Washington, D.C.: 1974), 121(5), 578-585. 3. Corneli, A.L.*, Bentley, M. E., Sorenson, J. R., Henderson, G. E., van der Horst, C., Moses. A, Nkhoma, J., Tenthani, L., Ahmed, Y., Heilig, C. M., Jamieson, D.J. (2006). Using formative research to develop a context-specific approach to informed consent for clinical trials. Journal of Empirical Research on Human Research Ethics, 1(4), 45. 4. Easter, M. M.*, Linnan, L. A., Bentley, M. E., DeVellis, B. M., Meier, A., Frasier, P. Y., et al. (2007). "Una mujer trabaja doble aqui": Vignette-based focus groups on stress and work for latina blue-collar women in eastern North Carolina. Health Promotion Practice, 8(1), 41-49. 5. Dearden, K. A., Hilton, S., Bentley, M. E., Caulfield, L. E., Wilde, C., Ha, P. B., et al. (2009). Caregiver verbal encouragement increases food acceptance among Vietnamese toddlers. The Journal of Nutrition, 139(7), 1387-1392. 6. Bentley, M. E., Wasser, H.M.*, Creed-Kanashiro, H.M. (2011). Responsive feeding and child undernutrition in low- and middle-income countries. The Journal of Nutrition. doi: 10.3945/jn.110.130005. 7. Wasser, H.*, Bentley, M., Borja, J., Goldman, B.D., Thompson, A., Slining, M., Adair, L. (2011). Infants perceived as "fussy" are more likely to receive complementary foods before 4 months. Pediatrics, 127(2), 22 Shroff, M.R., Griffiths, P.L., Suchindran, C., Balakrishna, N., Vazir, S, Bentley, M.E. Does maternal autonomy influence feeding practices and infant growth in rural India? (In Press, Soc Sci Med). 8. Thompson, A.L., Adair, L.S., Bentley, M.E. Pressuring and restrictive feeding styles influence infant feeding and size among a low-income African-American sample (Accepted, Obesity). PHS 398/2590 (Rev. 06/09) Page Biographical Sketch Format Page Program Director/Principal Investigator (Last, First, Middle): . 9. Mehta, U. J.*, Siega-Riz, A. M., Herring, A. H., Adair, L. S., Bentley, M. E. (2012). Pregravid body mass index, psychological factors during pregnancy and breastfeeding duration: Is there a link? Matern Child Nutr 8(4), 423-433. 10. Kayira, D., Bentley, M. E., Wiener, J., Mkhomawanthu, C., King, C. C., Chitsulo, P., Chigwenembe, M., Ellington, S., Hosseinipour, M. C., Kourtis, A. P., Chasela, C., Tembo, M., Tohill, B., Piwoz, E. G., Jamieson, D. J., van der Horst, C., & Adair, L. (2012). A lipid-based nutrient supplement (LNS) mitigates weight loss among HIV-infected women in a factorial, randomized trial to prevent mother-to-child transmission during exclusive breastfeeding. American Journal of Clinical Nutrition, 95(3), 759-765. 11. Flax, V. L.*, Mäkinen, S., Ashorn, U., Cheung, Y. B., Maleta, K., Ashorn, P., Bentley, M. E. (2013). Responsive feeding and child interest in food vary when rural Malawian children are fed lipid-based nutrient supplements or local complementary food. Matern Child Nutr. 9(3), 369-380. 12. *Flax, V. L., Bentley, M. E., Chasela, C. S., Kayira, D., Hudgens, M. G., Knight, R. J., Soko, A., Jamieson, D. J., van der Horst, C. M., & Adair, L. S. (2012). Use of lipid-based nutrient supplements by HIV-Infected Malawian women during lactation has no effect on infant growth from 0 to 24 Weeks. J Nutr., 142(7), 1350-1356. 13. Hoffman, E. R*. Bentley, M. E., Hamer, R. M., Hodges, E. A., Ward, D. S., Bulik, C. M. (2012). A comparison of infant and toddler feeding practices of mothers with and without histories of eating disorders. Matern Child Nutr. [Epub ahead of print] doi: 10.1111/j.1740-8709.2012.00429.x. 14. Thompson A. L., Adair L. S., & Bentley M. E. (2013). Maternal characteristics and perception of temperament associated with infant TV exposure. Pediatrics, 131(2), e390-e397. 15. Thompson, A. L. & Bentley, M. E. (2013). The critical period of infant feeding for the development of early disparities in obesity. Soc Sci Med, 97, 288-296. 16. Thompson, A. L., Adair, L. S., & Bentley, M. E. (2013). Pressuring and restrictive feeding styles influence infant feeding and size among a low-income African-American sample. Obesity, 21(3), 562-571. 17. Bentley, M. E., Johnson, S. L., Wasser, H., Creed-Kanashiro, H., Shroff, M., Fernandez, S., Rao, F., & Cunningham, M. (2014). Formative research methods for designing culturally appropriate, integrated child nutrition and development interventions: An overview. Annals of the New York Academy of Sciences, 1308, 54-67. 18. Flax, V. L., Bentley. M. E., Combs, G. F. Jr., Chasela, C. S., Kayira, D., Tegha, G., Kamwendo, D., Daza, E. J., Fokar, A., Kourtis, A. P., Jamieson, D. J., van der Horst, C. M., & Adair, L. S. (2014). Plasma and breastmilk selenium in HIV-infected Malawian mothers are positively associated with infant selenium status but are not associated with maternal supplementation. Am J Clin Nutr., 99(4), 950-956. 19. Flax, V. L., Negerie, M., Ibrahim, A. U., Leatherman, S., Daza, E. J., & Bentley, M. E. (2014). Integrating group counseling, cell phone messaging, and participant-generated songs and dramas into a microcredit program increases Nigerian women’s adherence to international breastfeeding recommendations. J Nutr. [Epub ahead of print] doi: 10.3945/jn.113.190124 20. Siega-Riz, A. M., Estrada Del Campo, Y., Kinlaw, A., Reinhart, G. A, Allen, L. H., Shahab-Ferdows, S., Heck, J., Suchindran, C. M., & Bentley, M. E. (2014). Effect of supplementation with a lipid-based nutrient supplement on the micronutrient status of children aged 6-18 months living in the rural region of Intibucá, Honduras. Paediatr Perinat Epidemiol., 28(3), 245-254. 21. Ablah, E., Biberman, D. A., Weist, E. M., Buekens, P., Bentley, M. E., Burke, D., Fionnegan, J. R., Flahault, A., Frenk, J., Gotsch, A. R., Klag, M. K., Lopez, R., M. H., Nasca, P., Shortell, S., & Spencer, H. C. (2014). Improving Global Health Education: Development of a Global Health Competency Model. Am J Trop Med Hyg, 90(3), 560-565. 22. Widen, E. M., Bentley, M. E., Kayira, D., Chasela, C. S., Daza, D. J., Kacheche, Z. K., Tegha, G., Jamieson, D. J., Kourtis, A. P., van der Horst, C. M., Allen, L. H., Shahab-Ferdows, S., & Adair, L. S. for the BAN Study Team. (2014). Changes in soluble transferrin receptors and hemoglobin concentrations in Malawian mothers are associated with those values in their exclusively breastfed, HIV-exposed infants. J Nutr., 144(3), 367-374.

PHS 398/2590 (Rev. 06/09) Page Biographical Sketch Format Page Program Director/Principal Investigator (Last, First, Middle): . D. Research Support

Ongoing Research Support R01-HD073237 Bentley (PI) 09/01/12-09/01/17 Role: PI National Institutes of Health, NICHD Mothers and Others: Family-based Obesity Prevention for Infants and Toddlers This research will evaluate a community-based intervention for African-American women (and one other individual of her choice) who are recruited during pregnancy and followed until the infant is 18 months reduces the risk of obesity in their children and leads to optimal growth and development.

6015-S03 Curtis (PI) 05/11/12-05/06/17 Role: Co-Investigator Industry Sponsor (Westat, Inc.) Monitoring and Evaluation for Feed the Future Feedback Program Feedback will be a major evaluation, performance monitoring, and knowledge sharing program whose primary objective is to provide the best available empirical evidence from the FTF Initiative to inform policy, investment, and intervention decisions aimed at improving food security in vulnerable countries.

No Grant Number Bartram (PI) 08/23/13-02/22/16 Role: Collaborating Investigator Michael and Susan Dell Foundation Understanding How Pilot Programs Become Self-sustaining at Scale: Social Enterprises and Water in Schools of Delhi and Jaipur. Our main goal is to analyze how a social enterprise model of drinking water provision in Delhi and Jaipur can be enhanced for long term performance. Recommend steps required to transfer and scale to other schools in India states.

No Grant Number Handa (PI) 11/01/09-10/31/14

Role: Collaborating Investigator This project will provide technical assistance to data collection and analysis in order to evaluate the impact of social cash transfer schemes in 3 Africa countries: Malawi, Rwanda and Ethiopia. Three rounds of longitudinal data will be collected, at baseline and two follow-up periods, of program participants and a control group selected through both experimental and non-experimental methods. Five meta-analyses will be conducted in year 5 that will bring together the overall results from the 3 evaluations, and provide lessons learned on the impact of cash grants and other complementary services on the health, education and welfare of children in Africa.

Completed Research Support 1R24TW008810-01 Bentley (PI) 09/15/10-08/31/11 Water Wisdom: Developing Local-Global Capacities in Managing Water This project will develop a one-year post-doctoral training program for addressing water and sanitation issues through a team-based, multi-disciplinary approach. Role: PI

OPP53107 Bentley (PI) 09/01/09-08/31/12 Improving Nutritional Status and Health of Infants and Lactating Women through the Use of Lipid Based Nutrition Supplements (LNS): Evidence from a Longitudinal, Randomized Trial in Lilongwe, Malawi Our main goal is to provide the scientific evidence to support the broad use of low-cost LNS to enhance the nutritional status of women and children. Role: PI

1R25TW007493 Bentley (PI) 09/29/05-08/31/11 UNC-Chapel Hill Framework Program in Global Health To expand global health curriculum and research opportunities campus wide and engage faculty and students in an interdisciplinary study of global health issues. Role: PI

PHS 398/2590 (Rev. 06/09) Page Biographical Sketch Format Page Program Director/Principal Investigator (Last, First, Middle): .

3R25TW007493-03S1 Bentley (PI) 9/01/10-8/31/12 Support the implementation of a new professional online Global Health Certificate in Fall 2010, as well as offering distance global health courses to MPH students in the University of\Malawi College of Medicine, Division of Public Health. Role: PI

No Grant Number Bentley (PI) 11/01/10-04/30/12 Healthy and Secure 0-2 year olds UNC – ChildFund Innovation Lab to Define the ChildFund Program Offer Role: PI

No Grant Number Handa (PI) 11/01/09-10/31/14 Role: Collaborating Investigator This project will provide technical assistance to data collection and analysis in order to evaluate the impact of social cash transfer schemes in 3 Africa countries: Malawi, Rwanda and Ethiopia. Three rounds of longitudinal data will be collected, at baseline and two follow-up periods, of program participants and a control group selected through both experimental and non-experimental methods. Five meta-analyses will be conducted in year 5 that will bring together the overall results from the 3 evaluations, and provide lessons learned on the impact of cash grants and other complementary services on the health, education and welfare of children in Africa. Role: Collaborating Investigator

No Grant Number Van der Horst (PI) 09/30/04-09/29/14 Breast-feeding, Antiretrovirals, and Nutrition in HIV (BAN) This study is currently analyzing data from Malawi in a drug and nutrition related clinical trial that tested the efficacy of providing nutrition supplements or ARV drugs to HIV positive mothers or their infants. Role: Co-Investigator

No Grant Number Bentley (PI) 05/15/11-06/01/13 Linking Microcredit, Technology, and Promotion of IYCF Breastfeeding Guidelines in Bauchi State, Nigeria This is a behavioral intervention trial testing the promotion of breastfeeding and complementary feeding messages delivered through existing women’s microcredit groups through face-to-face and text-messaging channels. Role: PI

1-R21-ES016729-02 Entwisle (PI) 09/30/07-06/30/11 Dynamically Integrating Macro and Micro Processes With unique data for Northeast Thailand, an empirically informed, spatially explicit agent-based model of interrelationships among individual behavior, household land use and wealth, social networks, and communities was constructed. Role: Collaborating Advisor

1R34MH080750-02 Bulik (PI) 06/06/08-02/28/11 Breaking the Cycle of Risk: Intervention for Mothers with Eating Disorders This project developed a parenting intervention for mothers with current or past eating disorders called NURTURE (Networking, Uniting, and Reaching out To Upgrade Relationships and Eating). Role: Investigator

1R03HD057775-02 Bentley (PI) 09/30/07-08/31/10 The Feasibility of Replacement Feeding as an HIV Prevention Method in Malawi The Breastfeeding, Antiretroviral, and Nutrition (BAN) study was a randomized controlled trial in Lilongwe, Malawi, that evaluated antiretroviral and nutrition interventions to reduce mother-to-child transmission of HIV during breastfeeding. This information will help to guide the Malawi government policy and others on the feasibility of the provision of a high-quality breast milk replacement for HIV positive mothers after exclusive breastfeeding counseling. Role: PI PHS 398/2590 (Rev. 06/09) Page Biographical Sketch Format Page