Preliminary Report for the Workshop on Applied Statistics to Be Held in the Department s1

Final report for the “Workshop on Applied Statistics” held in the Department of Chemical Engineering of the School of Sciences and Technology, University of Coimbra (Portugal)

Partners involved Marco Reis QUAL Pedro Saraiva QUAL Tony Greenfield Greenfield Research

Speakers

Tony Greenfield, PhD, BSc (Statistics), CStat Belmiro Duarte, PhD, Eng. Marco Reis, Eng.

Overview Several statistical approaches to data generation and analysis were presented in this workshop and some practical applications were shown. Even though the presented methods can be used in many different contexts, the presentations were organized according to the specific domains of the case studies they addressed: Health or Industry.

Audience The targeted audience of this workshop was mainly:

. Practitioners, to extend their own expertise in data analysis; . Students, as an important complement to subjects that are not fully covered in the current undergraduate syllabus; . Educators, who find, in the case studies and simulation tools, new opportunities to pass on information regarding non-trivial statistical tools, in a visual and contextual way. Program

Part I – Applications in Health 09.30 – Tony Greenfield Simulation of clinical trials 11.00 – Belmiro Duarte Knowledge extraction in health data 11.30 –Coffee break Part II – Applications in Industry 11.45 - Marco Reis Multivariate linear regression methods with applications to industrial data 13.15 – Lunch break

14.30 - Belmiro Duarte Process improvement through statistical knowledge 16.00 - Tony Greenfield Simulation of manufacturing processes

17.30 - Closure

Activities conduced Activities conduced, include:  Preparation of materials for advertisement (leaflets, wall papers, abstracts);  Divulgation (Portuguese Universities, Institutes, Industries, Hospitals and Service Providers);  Preparation of materials to be presented (presentation slides, case studies, software);  Logistic organization (room, projector, PC, water, coffee);

Materials delivered to attendees Delivered materials include:  Schedule and abstracts of presentations;  Presentation handouts;  ENBIS leaflet;  Questionnaire;  Paper, Dossier, Coffee tickets; Outcomes of the seminar Understanding the importance of variability and handling it when it is present, usually requires some sort paradigm shift from what are the traditional way of people solving real world problems. During the workshop several statistical techniques were introduced and applied to real world case studies, in order to expose practitioners to the statistical way of approaching real world problems. By the end of the workshop, we would expect that attendees can recognize that, not only variability is almost always present, but that it requires a special way of thinking in order to solve problems where it appears (“statistical thinking”), with its own toolbox. We urged them to try them on, and show up with question, in order to give continuity to what was presented. By this time, 1 ½ weeks after the workshop, we have already received several contacts from attendees of the workshop exposing their problems and looking for more information in how to solve them using the tools presented therein, as well as invitations for more in depth presentations regarding certain particular topics.

Attendance list

Name Affiliation 1 José Vítor Martins Ramos Centro de Informática e Sistemas da UC 2 Sónia Martins Fiuza Departamento de Bioquímica Rita Figueiredo Moutinho 3 Calheiros Cruz Departamento de Bioquímica 4 Andreia de Faria Martins Rosa Hospital da Universidade de Coimbra 5 Alexandra Maria Galvão Ribeiro Instituto Superior de Engenharia de Coimbra Filipe Manuel Rodrigues Vieira 6 Martins Associação para a Investigação Biomédica i Inovação em Luz e Imagem 7 Luis Alexandre Mano Moutinho Departamento de Engenharia Civil da Universidade de Coimbra 8 Rui Carlos Cardoso Martins Departamento de Engenharia Química da Universidade de Coimbra 9 Nuno Emanuel Alves Rei Departamento de Química da Universidade de Coimbra 10 Dina Alexandra Angélico Departamento de Engenharia Química da Universidade de Coimbra 11 Pedro Manuel Rodrigues Francisco Departamento de Engenharia Química da Universidade de Coimbra 12 Cristina Gaudêncio Baptista Departamento de Engenharia Química da Universidade de Coimbra 13 Rita Alexandra Correia Navarro Faculdade de Ciências e Tecnologia da Universidade de Coimbra 14 Andrey Romanenko Departamento de Engenharia Química da Universidade de Coimbra 15 Jorge Manuel dos Santos Rocha Departamento de Engenharia Química da Universidade de Coimbra 16 Vitória del Pino Alvarez Departamento de Engenharia Química da Universidade de Coimbra 17 Paulo Alexandre Quadros Departamento de Engenharia Química da Universidade de Coimbra 18 João Miguel Coías Departamento de Engenharia Química da Universidade de Coimbra 19 Sónia Isabel Brás Castanheira Departamento de Engenharia Química da Universidade de Coimbra 20 Maria da Graça Carvalho Departamento de Engenharia Química da Universidade de Coimbra 21 Tatiana de Matos Póvoas Departamento de Engenharia Química da Universidade de Coimbra Gustavo Vieira Gonçalves Pacheco 22 Duarte Departamento de Engenharia Química da Universidade de Coimbra 23 João Pedro Redondo Fernandes Departamento de Engenharia Química da Universidade de Coimbra 24 Pedro Alexandre Seabra Oliveira Departamento de Engenharia Química da Universidade de Coimbra 25 Isabel Maria Teixeira Moutinho Departamento de Engenharia Química da Universidade de Coimbra 26 Jorge Manuel Lemos Ferreira Departamento de Engenharia Química da Universidade de Coimbra Catarina Alexandra Fernandes 27 Duarte Departamento de Engenharia Química da Universidade de Coimbra 28 António Paulo Mendes de Sousa RAIZ - Instituto de Investigação da Floresta e Papel 30 Cristina Barros Escola Superior de Tecnologia e Gestão de Leiria - Instituto Politécnico 31 Raquel Costa Departamento de Engenharia Química da Universidade de Coimbra Ana Sofia LeonardoVilela de 32 Matos Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa 33 Pedro Nuno Simões Departamento de Engenharia Química da Universidade de Coimbra 34 Maria Helena Gil Departamento de Engenharia Química da Universidade de Coimbra 35 Fernando Garcia Departamento de Engenharia Química da Universidade de Coimbra 36 Margarida Quina Departamento de Engenharia Química da Universidade de Coimbra 37 Ana Paula Egas Departamento de Engenharia Química da Universidade de Coimbra 38 António Portugal Departamento de Engenharia Química da Universidade de Coimbra 39 Licínio Ferreira Departamento de Engenharia Química da Universidade de Coimbra 40 Tavares da Silva Departamento de Engenharia Química da Universidade de Coimbra 41 Luisa Durães Departamento de Engenharia Química da Universidade de Coimbra 42 Paulo Brito Departamento de Engenharia Química da Universidade de Coimbra

Results of questionnaire

The results of the questionnaire given to attendees (see Appendix), are now briefly presented. The number of questionnaires collected was 13. For the first 5 questions, five levels of satisfaction were given for attendees in order to select the one that, for each case, most correspond to his judgment. Using “1” for “Not at all” and “5” for “Very Much”, we can see that the rounded average scores were:

(Question: Did the event meet your expectations as regards the following items:) Content: 4 (“Quite a lot”) Practical examples: 4 (“Quite a lot”) Fitting my situation: 3 (“Some/OK”) I can use the Techniques: 3 (“Some/OK”) Style of delivery: 4 (“Quite a lot”)

Regarding the reminding questions:

Question: Did you find the material difficult to follow? The results were (%): no some yes blank 69 23 0 8

Question: Would you recommend the event to others? The results were (%): no some yes blank 8 0 85 8

Question: Which techniques are you likely to use? The results were (%): MVA (PCA,PLS, etc.) 46 Sim. Clinic. Trials 15 SPC 8 none 23

Addressing now only what some people suggested that was missing, we take note of the following items:

 Practical exemplification of software “in loco”;  More examples from industry;  Introduction of some basics, before getting into more complex tools;  Avoid specific software. Appendix: Questionnaire Pro-ENBIS Questionnaire

In order to help us to improve our events, please complete this brief confidential questionnaire.

EVENT TITLE:- Workshop de Estatística Aplicada

DATE:- 28.4.2004

Did the event meet your expectations as regards the following items:

Not at all Not much Some/OK Quite a lot Very much

Content

Practical examples

Fitting my situation

I can use the Techniques

Style of delivery

Did you find the material difficult to

follow?

Would you recommend the event to

others?

Which techniques are you likely to use?

Is their anything 'missing' from the event?

General Comments:

DATE: Thank you very much for your help

The Pro-ENBIS project is supported by funding under the European Commission's Fifth Framework 'Growth' Programme via the Thematic Network "Pro- ENBIS" contract reference: G6RT-CT-2001-05059.