Linear Mixed Effects Regression Models Using Conditioning Phase, Estradiol Level, Progesterone

Table S1

Linear mixed effects regression models using Conditioning Phase, Estradiol level, Progesterone level, PTSD group membership, and Task Order to predict the differential skin conductance response to the CS+, compared to the CS-.

Source B SE 95% Conf. Int. p Differential SCR for Early Extinction minus Differential SCR for Acquisition Intercept -.055 .117 -.293 - .182 .640 Estradiol .001 .004 -.007 - .010 .714 Progesterone .030 .019 -.009 - .069 .129 PTSD group -.025 .175 -.380 - .330 .887 Estradiol X -.001 .000 -.002 - .000 .148 Progesterone Estradiol X PTSD .003 .006 -.010 - .016 .647 group Progesterone X -.063 .028 -.120 - -.007 .030 PTSD Group Estradiol X .001 .001 -.001 - .002 .323 Progesterone X PTSD group Differential SCR for Late Extinction minus Differential SCR for Early Extinction Intercept -.034 .049 -.133 - .064 .485 Estradiol .003 .002 -.001 - .006 .099 Progesterone -.016 .008 -.032 - .001 .066 PTSD group .050 .072 -.096 - .197 .492 Estradiol X .000 .000 .000 - .001 .186 Progesterone Estradiol X PTSD -.002 .003 -.007 - .004 .555 group Progesterone X .016 .012 -.007 - .040 .172 PTSD Group Estradiol X .000 .000 -.001 - .000 .346 Progesterone X PTSD group Differential SCR for Extinction Retention minus Differential SCR for Early Extinction Intercept -.119 .088 -.299 - .060 .186 Estradiol .000 .003 -.006 - .006 .929 Progesterone -.025 .015 -.055 - .004 .092 PTSD group .284 .129 .022 - .545 .034 Estradiol X .001 .000 .000 - .002 .049 Progesterone Estradiol X PTSD -.003 .006 -.015 - .009 .599 group Progesterone X .046 .023 -.002 - .093 .060 PTSD Group Estradiol X -.001 .001 -.002 - .000 .029 Progesterone X PTSD group Differential SCR for Extinction Retention minus Differential SCR for Late Extinction Intercept -.091 .099 -.292 - .111 .368 Estradiol -.002 .003 -.009 - .004 .515 Progesterone -.011 .016 -.043 - .021 .474 PTSD group .241 .146 -.054 - .537 .106 Estradiol X .000 .000 .000 - .001 .242 Progesterone Estradiol X PTSD -.002 .006 -.014 - .011 .776 group Progesterone X .030 .024 -.020 - .081 .228 PTSD Group Estradiol X -.001 .001 -.002 - .000 .117 Progesterone X PTSD group Note. Conf. Int.= confidence interval; PTSD = posttraumatic stress disorder; SCR = Skin conductance response. Figure S1. Extinction Retention as Predicted by Estradiol, Progesterone, and PTSD Group. Extinction retention is defined as differential SCR [measured in microSiemens (μS)] for the extinction retention phase minus differential SCR for the early extinction phase. Lower scores indicate better extinction retention.