Table S1

Linear mixed effects regression models using Conditioning Phase, Estradiol level, Progesterone level, PTSD group membership, and Task Order to predict the differential skin conductance response to the CS+, compared to the CS-.

Source B SE 95% Conf. Int. p Differential SCR for Early Extinction minus Differential SCR for Acquisition Intercept -.055 .117 -.293 - .182 .640 Estradiol .001 .004 -.007 - .010 .714 Progesterone .030 .019 -.009 - .069 .129 PTSD group -.025 .175 -.380 - .330 .887 Estradiol X -.001 .000 -.002 - .000 .148 Progesterone Estradiol X PTSD .003 .006 -.010 - .016 .647 group Progesterone X -.063 .028 -.120 - -.007 .030 PTSD Group Estradiol X .001 .001 -.001 - .002 .323 Progesterone X PTSD group Differential SCR for Late Extinction minus Differential SCR for Early Extinction Intercept -.034 .049 -.133 - .064 .485 Estradiol .003 .002 -.001 - .006 .099 Progesterone -.016 .008 -.032 - .001 .066 PTSD group .050 .072 -.096 - .197 .492 Estradiol X .000 .000 .000 - .001 .186 Progesterone Estradiol X PTSD -.002 .003 -.007 - .004 .555 group Progesterone X .016 .012 -.007 - .040 .172 PTSD Group Estradiol X .000 .000 -.001 - .000 .346 Progesterone X PTSD group Differential SCR for Extinction Retention minus Differential SCR for Early Extinction Intercept -.119 .088 -.299 - .060 .186 Estradiol .000 .003 -.006 - .006 .929 Progesterone -.025 .015 -.055 - .004 .092 PTSD group .284 .129 .022 - .545 .034 Estradiol X .001 .000 .000 - .002 .049 Progesterone Estradiol X PTSD -.003 .006 -.015 - .009 .599 group Progesterone X .046 .023 -.002 - .093 .060 PTSD Group Estradiol X -.001 .001 -.002 - .000 .029 Progesterone X PTSD group Differential SCR for Extinction Retention minus Differential SCR for Late Extinction Intercept -.091 .099 -.292 - .111 .368 Estradiol -.002 .003 -.009 - .004 .515 Progesterone -.011 .016 -.043 - .021 .474 PTSD group .241 .146 -.054 - .537 .106 Estradiol X .000 .000 .000 - .001 .242 Progesterone Estradiol X PTSD -.002 .006 -.014 - .011 .776 group Progesterone X .030 .024 -.020 - .081 .228 PTSD Group Estradiol X -.001 .001 -.002 - .000 .117 Progesterone X PTSD group Note. Conf. Int.= confidence interval; PTSD = posttraumatic stress disorder; SCR = Skin conductance response. Figure S1. Extinction Retention as Predicted by Estradiol, Progesterone, and PTSD Group. Extinction retention is defined as differential SCR [measured in microSiemens (μS)] for the extinction retention phase minus differential SCR for the early extinction phase. Lower scores indicate better extinction retention.