International Registry of Acute Aortic Dissection (IRAD)

Abstracts Published or In Press

Das S, Isselbacher E, Hagan P, Evangelista A, Fattori R, Suzuki T, Oh JK, Sechtem U, Robles JM, Deutsch HJ, Gilon D, Karavite D, Russman P, Armstrong WF, Deeb GM, Bruckman D, Nienaber C, Eagle KA. Practice variations in utilization of diagnostic techniques to evaluate acute aortic dissection - results from the International Registry of Aortic Dissection (IRAD). J Am Coll Cardiol 1999; 33(2):310A.

Hagan PG, Nienaber CA, Das S, Evangelista A, Fattori R, Suzuki T, Oh JK, Sechtem U, Robles JM, Deutsch HJ, Gilon D, Bruckman D, Karavite D, Russman P, Mehta RJ, Pape L, Armstrong WF, Deeb GM, Isselbacher E, Eagle KA. Acute aortic dissection: Modern clinical spectrum - results from the International Registry for Aortic Dissection (IRAD). J Am Coll Cardiol 1999; 33(2):242A.

Nienaber CA, Fattori R, Bruckman D, Das S, Evangelista A, Suzuki T, Oh JK, Sechtem U, Robles JM, Deutsch HJ, Gilon D, Pape L, Karavite D, Russman P, Deeb GM, Isselbacher E, Eagle KA. Current management of Type A acute aortic dissection: results from the International Registry of Aortic Dissection. J Am Coll Cardiol 1999; 33(2):242A.

Moore AG, Oh JK, Bruckman D, Karavite D, Malouf J, Russman PL, Hagan P, Isselbacher E, Evangelista A, Pape L, Fattori R, Suzuki T, Sechtem U, Robles JM, Deutsch HJ, Gilon D, Das S, Deeb GM, Nienaber CA, Eagle KA. The utility of transesophageal echocardiography in the diagnosis and management of aortic dissection: an analysis of data from the International Registry of Aortic Dissection (IRAD). J Am Coll Cardiol 1999; 33(2):470A.

Evangelista A, Bruckman D, Gaca C, Hagan PG, Oh JK, Malouf J, Moore AG, Sechtem U, Llovet S, Deutsch HJ, Diedrichs H, Gilon D, Nienaber CA, O’Gara PT, Karavite DJ, Russman PL, Armstrong WF, Deeb GM, Suzuki T, Isselbacher E, Eagle KA, Pape L. Presentation, clinical findings and outcomes among patients with acute definitive intramural hematoma – results from the International Registry of Acute Aortic Dissection (IRAD). J Am Coll Cardiol 2000; 35:324A.

Fattori R, Napoli G, Bruckman D, Isselbacher E, Evangelista A, Oh JK, Malouf J, Sechtem U, Llovet A, Deutsch HJ, Diedrichs H, Gilon D, Pape L, O’Gara PT, Karavite DJ, Russman PL, Hagan PG, Armstrong WF, Deeb BM, Suzuki T, Eagle KA, Nienaber CA. Acute aortic dissection in women: Comparative analysis among genders – results from the International Registry of Acute Aortic Dissection (IRAD). J Am Coll Cardiol 2000; 35:284A.

Eagle KA, Bruckman D, Isselbacher E, Evangelista A, Fattori R, Oh JK, Moore AG, Malouf J, Sechtem U, Llovet A, Deutsch HJ, Gilon D, Pape L, O’Gara PT, Karavite D, Russman P, Hagan PG, Armstrong WF, Deeb GM, Nienaber CA, Suzuki T. Predictive of mortality in patients with type A acute aortic dissections – results from the International Registry of Acute Aortic Dissection (IRAD). J Am Coll Cardiol 2000; 35:323A.

Freeman RV, Bruckman D, Hagan P, Suzuki T, Isselbacher E, Evangelista A. Fattori R, Oh JK, Moore AG, Sechtem U, Llovet A, Deutsch HJ, Gilon D, Pape L, O’Gara PT, Karavite DJ, Russman PL, Armstrong WF, Deeb GM, Nienaber CA, Eagle KA. A non-linear model for mortality prediction in patients with Type A Acute Aortic Dissection. A study from the International Registry of Acute Aortic Dissection (IRAD). J Am Coll Cardiol 2000; 35:275A.

Januzzi JL, Sabatine MS, Evangelista A, Bruckman D, Fattori R, Oh JK, Moore AG, Malouf J, Sechtem U, Llovet A, Deutsch HJ, Gilon D. Iatrogenic aortic dissection—results from the International Registry of Aortic Dissection (IRAD). Circulation 2000; 102:.

irad-published-abstracts-0309 Mehta RJ, O’Gara PT, Hagan PG, Bossone E, Llovet A, Cooper J, Bruckman D, Gilon D. Acute aortic dissection in the elderly: Clinical characteristics, management, and outcomes in the current era. J Am Coll Cardiol 2001; 37:145A.

Mehta RH, Hagan PG, Suzuki T, Bossone E, Gilon D, Llovet A, Cooper J, Pape L, Armstrong WF, Bruckman D, Nienaber CA, Eagle KA. Predicting in-hospital mortality in acute Type A aortic dissection: lessons from the International Registry of Aortic Dissection (IRAD). J Am Coll Cardiol 2001; 37:492A.

Fattori R, Eagle KA, Williams D, Cooper J, Isselbacher E, Nienaber C. Percutaneous therapeutic procedures in acute aortic dissection: evidence for benefit is mounting. J Am Coll Cardiol 2001; 37:514A.

Suzuki T, Nienaber CA, Hagan PG, Bossone E, Gilon D, Cooper JV, Bruckman D, Armstrong WF, Eagle KA, Mehta RH. Mortality in type B aortic dissections in the current era: Results from the International Registry of Aortic Dissection (IRAD). J Am Coll Cardiol 2001; 37:514A.

Evangelista A, Elorz C, Avegliano G, Cooper J, Nienaber C, Fattori R, Suzuki T, Sechtem U, Pape L, Eagle K. Management and one-month mortality in patients with acute aortic intramural haematoma. Results from the International Registry of Acute Aortic Dissection (IRAD). European Heart Journal 2001; 22:599.

Mehta RH, Hagan PG, Suzuki T, Bossone E, Gilon D, Llovet A, Cooper J, Armstrong WF, Nienaber CA, Eagle KA. Multivariable model to predict in-hospital mortality in acute type A aortic dissection. European Heart Journal 2001; 22:598.

Fattori R, Eagle KA, Williams D, Mehta RH, Maroto LC, Cooper J, Isselbacher E, Nienaber CA. Percutaneous therapeutic procedures in acute aortic dissection: lessons from International Registry of Acute Aortic Dissection. European Heart Journal 2001; 22:599.

Suzuki T, Nienaber CA, Hagan PG, Bossone E, Gilon D, Cooper J, Armstrong WF, Maroto LC, Eagle KA, Mehta RH. Predicting mortality in type B acute aortic dissections. European Heart Journal 2001; 22:323.

Bossone E, Rampoldi V, Trimarchi S, Hagan PG, Cooper J, Smith D, Suzuki T, Nienaber C, Eagle KA, Mehta RH. Pulse deficit: an independent predictor of in-hospital complications and mortality in patients with type A aortic dissection. Circulation 2001; 104:524-525.

Mehta RH, Manfredini R, Bossone E, Smith DE, Cooper JV, Llovet A, Suzuki T, Nienaber CA, Eagle KA. Does circadian rhythm influence the risk of acute aortic dissection? J Am Coll Cardiol 2002; 39:241A.

Nallamothu BK, Mehta RH, Saint S, Eagle KA. Syncope in aortic dissection: diagnostic, prognostic, and clinical implications. J Am Coll Cardiol 2002; 39:241A.

Richartz BM, Cooper JV, Smith DE, Mehta RH, Eagle KA, Nienaber CA. Excess mortality of type A aortic dissection in women: impact of delayed diagnosis. J Am Coll Cardiol 2002; 39:241A.

Richartz BM, Smith DE, Cooper JV, Mehta RM, Eagle KA, Nienaber CA. New classification of aortic dissection with improved impact on prognosis. J Am Coll Cardiol 2002; 39:264A.

Mehta RH, Manfredini R, Hassan F, Bossone E, Cooper JV, Nienaber C, Isselbacher EM, Eagle KA. Seasonal variation in the risk of acute aortic dissections. European Heart Journal 2002; 4:10.

Richartz, BM, Schiller F, Bossone E, Cooper JV, Evangelista A, Nienaber CA. Aortic arch dissection as a distinct entity: lessons learned from IRAD. Circulation 2002; 106:473.

irad-published-abstracts-0309 Suzuki T, Mehta R, Sakomura Y, Sumiyoshi T, Bossone E, Trimarchi S, Cooper J, Smith D, Isselbacher E, Nienaber C. Clinical presentation, diagnosis, management and outcomes of acute type B aortic dissection in the current era – lessons from the international registry of aortic dissection (IRAD). Circulation 2002; 106:501.

Gilon D, Mehta RH, Oh JK, Januzzi JL, Bossone E, Cooper JV, Smith DE, Nienaber CA, Isselbacher EM. Clinical characteristics and in-hospital outcomes of patients with cardiac tamponade complicating acute type A aortic dissection. Circulation 2002; 106:672.

Al-Marayati F, Isselbacher EM, Mehta RH, O’Gara PT, Sechtem U, Bossone E, Evangelista A, Oh, JK, Nienaber CA, Eagle KA. Marfan syndrome: a distinct and highly lethal cause of aortic dissection; lessons from the international registry of aortic dissection. Circulation 2002; 106:473.

Beckman JA, Mehta RH, Bossone E, Cooper JV, Smith DE, Sechtem U, Pape L, O'Gara PT. Renal failure on presentation predicts morbidity and mortality in aortic dissection. J Am Coll Cardiol 2003; 41:235-236A.

Bossone E, Mehta RH, Trimarchi S, Cooper JV, Smith DE, Evangelista A, Myrmel T, Oh J, Nienaber CA, Eagle KA, Isselbacher EM. Coronary artery involvement in patients with acute type A aortic dissection: clinical characteristics and in-hospital outcomes. J Am Coll Cardiol 2003; 41:235A.

Januzzi JL, Isselbacher EM, Fattori R, Cooper JV, Smith DE, Eagle KA, Nienaber CA, Pape LA. Characterizing the young patient with aortic dissection: results from the International Registry of Aortic Dissection (IRAD). J Am Coll Cardiol 2003; 41:253A.

Eagle KA, Nienaber CA, Mehta RH, Cooper JV, Smith DE, Myrmel T, Sechtem U, Bossone E, Januzzi JL, Isselbacher EM. Trends in management and outcomes of acute aortic dissection: lessons learned from the first 1,000 patients enrolled in the International Registry of Acute Aortic Dissection (IRAD). J Am Coll Cardiol 2003; 41:529A.

Mehta RH, Manfredini R, Portaluppi F, Hutchison S, Cooper JV, Penn M, Bossone E, Evangelista A, Eagle KA, Nienaber CA. Influence of chronobiological variation in the risk of acute aortic dissection on in-hospital mortality. J Am Coll Cardiol 2003; 41:288A.

Trimarchi S, Nienaber CA, Rampoldi V, Mehta RH, Bossone E, Cooper JV, Smith DE, Oh JK, Isselbacher EM, Suzuki T, Eagle KA. Preoperative predictive risk model for mortality in patients with acute type A aortic dissection undergoing surgery: lessons from the International Registry of Acute Aortic Dissection (IRAD). J Am Coll Cardiol 2003; 41:512-513A.

Patel SJ, Mehta RH, Pape L, Hutchison S, Smith DE, Cooper JV, O’Gara PT, Suzuki T, Isselbacher EM, Nienaber CA, Eagle KA. Hospital volume and mortality in acute aortic dissection: does low volume predict worse outcome? J Am Coll Cardiol 2003; 41:304A.

Collins JS, Evangelista A, Nienaber CA, Bossone E, Cooper JV, Isselbacher EM, Penn M, Mehta RH. Differences in clinical features, management and outcomes of acute aortic dissection in patients with and without prior cardiac surgery. Circulation 2003; 108:480-481.

Bossone E, Isselbacher EM, Nienaber CA, Gilon D, Cooper JV, Evangelista A, Suzuki T, Mehta RH. Simple decision rule for risk stratification of elderly with acute type B aortic dissection. Circulation 2003; 108:481.

irad-published-abstracts-0309 Trimarchi S, Fattori R, Nienaber CA, Cooper JV, Smith DE, Rampoldi V, Sangiorgi G, Myrmel T, Suzuki T, Oh JK, Isselbacher EM, Eagle KA. Preoperative hemodynamic status as predictor of surgical mortality in acute type A aortic dissection patients: insights from the International Registry of Acute Aortic Dissection (IRAD). J Am Coll Cardiol 2004; 43:461-462A.

Bossone E, Mehta RH, Gilon D, Hutchison S, Distante A, Llovet A, O'Gara P, Cooper JV, Fang J, Januzzi J, Nienaber CA, Eagle KA, Armstrong WF. Prognostic role of transesophageal echocardiography in acute type A aortic dissection. J Am Coll Cardiol 2004; 43:19A

Tsai TT, Isselbacher EM, Nienaber CA, Evangelista A, Fang J, Smith DE, Cooper JV, Hutchison S, Bossone E, O'Gara P, Eagle KA, Mehta RH. Shock in patients with acute aortic dissection: clinical characteristics, risk factors and outcomes. J Am Coll Cardiol 2004; 43:22A.

Suzuki T, Trimarchi S, Smith D, Nienaber C, Evangelista A, Sakomura Y, Sumiyoshi T, Cooper JV, Pape L, Rampoldi V, Sangiorgi G, Fattori R, Isselbacher E, Eagle K. Early diagnosis of acute aortic dissection – identification of clinical variables associated with early diagnosis and determination of the usefulness of biochemical diagnosis as shown by the International Registry of Acute Aortic Dissection (IRAD) database. Circulation 2004; 110:370.

Mehta RH, Manfredini R, Bossone E, Fattori R, Evangelista A, Cooper JV, Sechtem U, Isselbacher EM, Nienaber CA, Eagle KA. The winter peak in the risk of acute aortic dissection is independent of the varying climatic conditions at different geographical locations. Circulation 2004; 110:670.

Mukherjee D, Eagle KA, Evangelista A, Sechtem U, Suzuki T, Trimarchi S, Llovet A, Myrmel M, O'Gara PT, Fang J, Cooper JV, Oh JK, Januzzi JL, Hutchison S, Fattori R, Pape LA, Isselbacher EM, Nienaber CA. Implications of periaortic hematoma in patients with acute aortic dissection: insights from the International Registry of Aortic Dissection. J Am Coll Cardiol 2005; 45:380A.

Pape LA, Januzzi J, Cooper JV, Fattori R, Evangelista A, Suzuki T, Trimarchi S, Bossone E, Oh J, Hutchison S, Beckman J, Nienaber CA, Isselbacher E, Eagle KA. Many type A aortic dissections occur at diameters less than general ly perceived. Circulation 2005; 112:534.

Tsai TT, Evangelista A, Nienaber C, Sechtem U, Fattori R, Myrmel T, Llovet A, Cooper JV, Fang J, Isselbacher E, Eagle KA. Long-term survival in patients presenting with type A aortic dissection: insights from the International Registry of Acute Aortic Dissection (IRAD). Circulation 2005; 112:534-535.

Tsai TT, Fattori R, Trimarchi S, Nienaber C, Myrmel T, Hutchison S, Sechtem U, Cooper JV, Fang J, Pape L, Januzzi J, Eagle KA, Isselbacher E. Long-term survival in patients with type B acute aortic dissection: insights from the International Registry of Acute Aortic Dissection (IRAD). Circulation 2005; 112:535.

Trimarchi S, Nienaber CA, Rampoldi V, Myrmel T, Suzuki T, Tolva V, Deeb MG, Upchurch G, Cooper JV, Fang J, Isselbacher EM, Sundt T, Eagle KA. Role and results of surgery in acute type B dissection: insights from the International Registry of Aortic Dissection (IRAD). Circulation 2005; 112:712.

Raghupathy A, Nienaber C, Myrmel T, Fattori R, Sechtem U, Oh J, Cooper JV, Eagle K, Isselbacher E, Bossone E. Geographical variation in acute type A aortic dissection: insights from the International Registry of Aortic Dissection (IRAD). Circulation 2005; 112:712.

Tsai TT, Evangelista A, Nienaber CA, Myrmel T, Sechtem U, Cooper JV, Suzuki T, Fattori R, Distante A, Sundt T, Beckman J, Januzzi J, Isselbacher EM, Eagle KA. Partial false lumen thrombosis as a predictor of mortality in patients with type B acute aortic dissection: insights from the International Registry of Acute Aortic Dissection (IRAD). J Am Coll Cardiol 2006; 47:315A.

irad-published-abstracts-0309 Rampoldi V, Trimarchi S, Eagle KA, Nienaber CA, Oh JK, Bossone E, Myrmel T, De Vincentiis C, Cooper JV, Fang J, Fattori R, Sechtem U, Isselbacher EM. Simple risk models to predict surgical mortality in acute aortic dissection: the IRAD score. J Am Coll Cardiol 2006; 47:274A.

Tsai TT, Eagle KA, Fattori R, Trimarchi S, Cooper JV, Isselbacher E, Nienaber C, Bossone E. Characterization of medically managed patients with acute type A aortic dissection: insights from the International Registry of acute Aortic Dissection (IRAD). European Heart Journal 2006.

Trimarchi S, Nienaber CA, Tsai T, Llovet A, Froe hlich J, Rampoldi V, Grassi V, Pape L, Oh J, Cooper JV, Gilon D, Fattori R, Isselbacher EM, Eagle KA. In search for optimal treatment of complicated acute type B aortic dissections: insights from the International Registry of Aortic Dissection (IRAD). Circulation 2006;114:432.

Tsai T, Nienaber CA, Isselbacher EM, Trimarchi S, Bossone E, Evangelista A, Oh JK, O’Gara P, Suzuki T, Hutchison S, Cooper JV, Meinhardt G, Myrmel T, Eagle KA, Froehlich J. Acute type A aortic dissection: does a primary tear in the aortic arch affect management and outcomes? Insights from the International Registry of Acute Aortic Dissection (IRAD). Circulation 2006; 114:432.

Tsai T, Isselbacher EM, Trimarchi S, Bossone E, Pape L, Januzzi JL, Evangelista A, Oh JK, Llovet A, Beckman J, Cooper JV, Froehlich J, Fattori R, Eagle KA, Nienaber CA. Acute type B aortic dissection: does aortic arch involvement affect management and outcomes? Insights from the International Registry of Acute Aortic Dissection (IRAD). Circulation 2006;114:433.

Fattori R, Tsai TT, Myrmel T, Hutchison SJ, Trimarchi S, Kische S, Demertzis S, Cooper JV, Eagle KA, Pyeritz RE, Isselbacher EM, Nienaber C A. Emergency treatment of acute type B dissection: is surgery still justified? Results from the International Registry of Aortic Dissection (IRAD). J Am Coll Cardiol 2007; 49:374A.

Suzuki T, Distante A, Sabino F, Sizza A, Villani M, Trimarchi S, Salerno J, Fracella S, Ignone G, De Rinaldis G, Nowak R, Birkhahn R, Hollander J, Counselman F, Bossone E, Eagle KA. A biomarker for diagnosing acute aortic dissection: preliminary experience with the smooth muscle troponin-like protein, calponin. J Am Coll Cardiol 2007; 49:374A.

Trimarchi S, Eagle KA, Nienaber CA, Suzuki T, O’Gara PT, Hutchison SJ, Rampoldi V, Bossone E, Evangelista A, Tsai TT, Froehlich JB, Cooper JV, Smith DE , Meinhardt GW, Sundt III TM, Myrmel T, Isselbacher EM. Importance of pain and hypertension in acute type B aortic dissection: insights from the International Registry of Acute Aortic Dissection (IRAD). J Am Coll Cardiol 2007; 49:284A.

Ramanath VJ, Nienaber CA, Evangelista A, Oh JK, Llovet A, Beckman JA, Hirsch AT, Harris KM, Cooper JV, Tsai TT, Eagle KA, Isselbacher EM, Froehlich JB. Risk factors, management, and outcomes of recurrent acute aortic dissection in patients from the International Registry of Acute Aortic Dissection (IRAD). AHA Quality of Care and Outcomes Research Conference 2007.

Trimarchi S, Nienaber CA, Eagle KA, Rampoldi V, Tsai T, Froehlich J, Evangelista A, Cooper JV, Li J, Meinhardt G, Sundt III T, Bossone E, Isselbacher EM. Role of age in acute type A aortic dissection outcome: Report from The International Registry of Acute Aortic Dissection (IRAD). J Am Coll Cardiol 2008;51:314A

Genther D, Isselbacher E, Grzybowski M, Cooper JV, Eagle K, Tsai T, Bossone E, Harris KM, Evangelista A, Fattori R, Ramanath V, Nienaber CA, Froehlich J. Gender and race predict aortic size among type A aortic dissection patients: observations from the International Registry of Acute Aortic Dissection (IRAD). J Am Coll Cardiol 2008;51:352A

irad-published-abstracts-0309 Shiran H, Nienaber C, Isselbacher E, Tsai T, Meinhardt G, Cooper JV, Grzybowski M, Pyeritz R, Braverman A, Suzuki T, Eagle K, Froehlich JB. Effect of low suspicion presentation of type A acute aortic dissection on care and outcomes: data from the International Registry of Acute Aortic Dissection (IRAD). J Am Coll Cardiol 2008;51:312A

Shiran H, Isselbacher E, Nienaber C, Eagle K, Tsai T, Fattori R, Beckman J, O’Gara P, Pape L, Cooper JV, Grzybowski M, Ehrlich M, Froehlich J. Low suspicion presentation of type B acute aortic dissection leads to increased mortality: data from the International Registry of Acute Aortic Dissection (IRAD). J Am Coll Cardiol 2008;51:315A

Harris KM, Hirsch AT, Isselbacher EM, Tsai T, Froehlich J, Cooper JV, Fattori R, Strauss C, Evangelista A, Eagle K, Llovet A, Nienaber CA. Gender, clinical, and diagnostic contributors to delayed recognition and treatment of acute aortic dissection: the International Registry of Acute Aortic Dissection (IRAD). J Am Coll Cardiol 2008;51:313A

Booher AM, Isselbacher E, Nienaber CA, Froehlich JB, Trimarchi S, Cooper JV, Demertzis S, Meinhardt G, Ramanath VS, Januzzi JL, Harris KM, O'Gara P, Sundt T, Pyeritz RE, Eagle KA. Proximal thoracic aorta dimension and outcomes in acute type B dissection: insights from the International Registry of Acute Aortic Dissection. J Am Coll Cardiol 2009; 53: 450A.

Isselbacher E, Nienaber CA, Trimarchi S, Evangelista A, Cooper JV, Froehlich JB, Erlich M, Oh J, Januzzi JL, O'Gara P, Sundt T, Harris KM, Bossone E, Pyeritz RE, Eagle KA. The IRAD classification system- a modern method for characterizing mortality risk of aortic dissection based on time from symptom onset, dissection location, and treatment rendered. J Am Coll Cardiol 2009; 53: 447A.

Trimarchi S, Hutchison S, Isselbacher E, Pape L, Cooper JV, Froehlich JB, Evangelista A, Meinhardt G, Beckman J, Myrmel T, Eagle KA, Pyeritz RE, Hirsch AT, Nienaber CA. Descending aortic diameter of ≥ 6.0 is a poor predictor of type B aortic dissection. J Am Coll Cardiol 2009; 53:452A.

Tsai TT, Cooper JV, Woznicki EM, Nienaber CA, Isselbacher CA, Trimarchi S, Booher AM, Evangelista A, Bossone E, Meinhardt G, Fattori R, Pyeritz RE, Eagle KA, Froehlich JB. Trends in management and outcomes of acute aortic dissection: lessons learned from the first 2242 patients enrolled in the International Registry of Acute Aortic Dissection (IRAD). J Am Coll Cardiol 2009; 53:450A.

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