1. Which of the Following Statement(S) Is True?

1. Which of the following statement(s) is true? a. Due to inbreeding there is possibility of shortened lifespan of the newly created inbred strain of mice. b. It is possible to produce mice that are 100% homozygous after 20 successive brother x sister inbreeding generations. c. Congenic mice only differ by a single differential locus. d. Both a and b e. Both a and c 2. Which of the following are examples of myeloid cells? a. Neutrophils b. Basophils c. T lymphocytes d. All of the above e. Only a and b 3. Which of the following represent primary lymphoid tissue(s)? a. Bone marrow b. Thymus c. Spleen d. a and b e. all of the above 4. Which of the following statements describe immunogen? a. They must be at least 5-10 kDa b. They must have structural complexity. c. Haptens can be immunogens when presented to the immune response as a conjugate with a carrier protein. d. b and c are true e. a, b and c are true 5. Xenografts are grafts exchanged between a. Close friends b. Identical twins c. Xena the warrior princess and her enemies d. Different individuals within a species e. Different species 6. An adjuvant is a. A non-specific stimulator of immune activation b. A viral protein that enables the viral particle to bud from infected cells c. A type of T lymphocyte d. A very intensive inflammation e. None of the above 7. Antibodies can cause precipitation of target antigens as a result of a. Crosslinking the target b. Changing the salt concentration of the surrounding microenvironment c. Causing major structural changes in the 3 dimensional nature of the antigenic monomer d. Producing an endothermic reaction that causes cryoglobulin to fall out of solution e. All of the above [Type text] [Type text] [Type text] 8. Adjuvants work in several ways to enhance the immune response. Do you expect an adjuvant to work if co-injected with the synthetic polymer Teflon as the immune stimulus? a. Yes, Teflon is highly immunogenic molecules and adjuvant will only enhance the response further b. No, Teflon is not of sufficient size to provoke an immune response. c. No, Teflon is highly immunogenic and adjuvant cannot increase the large response that they elicit. d. No, Teflon is not of sufficient molecular complexity to induce an immune response. e. No, Teflon is recognized as “self” by the body 9. When a second exposure to the same microbial antigen occurs, which change to immunity would be most likely? a. The complement (C’) in the liquid fraction of the blood would precipitate. b. The lag phase of the immune response would be longer c. The vigor of the immune response would be greater than what happened after the initial exposure. d. The number of circulating T cells would decrease. e. None of the above 10. What is an idiotype? a. The antigenic shape of the Fc region b. The name of the most important class of antibody c. The antigenic shape of the antibody’s antigen combining site d. The allelic antigens that distinguish one antibody from antibodies of the same class and subclass in a different individual of the same species e. The force needed to hold antibodies to antigens