CHM 151C General Chemistry I, Fall 2008

CHEM 3371| Organic Chemistry 2 for Chemistry and Biochemistry Majors Spring 2016

Course Description

CHEM 3371: Organic Chemistry 2 for Chemistry and Biochemistry Majors

Credit Hours: 4

Lecture Meetings: MWF: 9 – 9:50 (HLMS 241)

Clickers: Not required

Webpage: http://www.colorado.edu/chem/yinlab/Pages/Teaching.html Lecture materials, quiz and exam keys, exam statistics will be posted on the webpage.

Pre-requisites: CHEM 3311 or CHEM 3351; CHEM 3321 or CHEM 3361 (all minimum grade C-).

Recitation Sessions: o CHEM 3371-114 (EKLC M2B36) M 12 -12:50 PM TA: Adam Csakai ([email protected])

o CHEM 3371-122 (EKLC M2B36) T 10 -12:50 AM TA: Adam Csakai ([email protected])

o CHEM 3371-126 (EKLC M2B36) T 2 -2:50 PM TA: Adam Csakai ([email protected])

This course provides a systematic study of theories, principles, and techniques of organic chemistry. Topics include structure and reactions of carboxylic acids and derivatives, aromatic compounds, and amines; introduction to the chemistry of heterocycles, carbohydrates, and amino acids; nomenclature of organic compounds; reaction mechanisms. Upon completion, students should be able to demonstrate an understanding of the fundamental concepts of organic topics. This course has been approved to satisfy the Comprehensive Articulation Agreement general education core requirement in natural sciences/mathematics.

CHEM 3351, FALL 2012 Page 1 of 7 Faculty Information Professor: Hubert Yin Office Location: JSCB A224 Office Hours: F: 1:30 – 3:30 (Other hours available by appt.) Telephone: 303-492-6786 Email: [email protected]

Major Course Goals Upon successful completion of the course, the student will be able to:

 understand organic molecules with correlations between chemical behavior and structure.

 systematically present basic nomenclature, reactions, and reaction mechanisms.

 understand the significance of organic chemistry in our contemporary world with particular emphases on biological and medical applications.

More specific objectives for each module of study will be distributed in class.

Textbooks  Marc Loudon, Organic Chemistry, 5th Ed. (ISBN: 978-0981519432)  Marc Loudon, Joseph G. Stowell Study Guide and Solutions Manual to Accompany Organic Chemistry, 5th Ed. (ISBN: 978-0981519449)

Grading Policies Grading Scale Your final grade will be based on the following scale: A=100-90; B=89.9-80; C=79.9-70; D=69.9 - 60; F=59.9-0 Areas of Assessment Your final course grade will be based upon the following weights for categories of assessments:  Chapter Quizzes (6) – 15% o 15-minute chapter quizzes every other week at the recitation sessions. One with the lowest score will be dropped.

 Mid-Term Exams (3) – 35% o Feb 9, Tuesday: 7 – 9 PM (HLMS 252) o Mar 8, Tuesday: 7 – 9 PM (HLMS 252)

CHEM 3351, FALL 2012 Page 2 of 7 o Apr 12, Tuesday: 7 – 9 PM (HLMS 252)

 Homework (12) – 10%

 Final Exam (1) – 40% o May 5, Thursday: 4:30 – 7 PM (TBA)

Make-up Work - Make-up work on assignments and homework will be permitted if the absence is excused. Otherwise the grade will be recorded as a zero. You must have documentation verifying the absence. If you are absent, it is your responsibility to find out what work is missed. If you miss a test a make-up exam will not be given. You will be required to take a cumulative final exam. If you miss more than one test, you will be dropped from the class. Academic Integrity In addition to good academic performance, students should exhibit honesty and integrity. If there is any question that academic honesty and integrity are not honored, students may be required to redo assignments in the presence of an instructor-selected monitor. Proof of dishonesty, including plagiarism, will make students subject to disciplinary action. Please see the "Syllabus Statements" on Page 6. Access/Disability Policy Please consult the "Syllabus Statements" on Page 6.

Attendance Policies

Enrollment in a chemistry class is a commitment by the student to all your assignments, schedules and requirements of the course. Attendance at lecture sessions is required and attendance may be taken at the beginning of class sessions. Those entering afterwards are considered “tardy.” Two tardies equal one absence .

Students are allowed a number of absences equal to the number of times the class meets each week. For lecture that will be three absences per semester. These should be used only when necessary. There are no absences allowed for an announced exam.

For absences beyond three, or absence from an exam, an “official” excuse must be submitted. An acceptable excuse is one due to circumstances beyond your control that prevented attendance of class and for which acceptable verification is provided--e.g., illness and a physician’s statement, traffic accident and a police report, school business and note from dean, etc. Credit can be given only for absences for which acceptable written verification is provided. Excuses for absences must be presented to the instructor upon return to class. For absences beyond six (6) a student will automatically be withdrawn from the class. Even if the absences are excused, a student must withdraw

CHEM 3351, FALL 2012 Page 3 of 7 after this number of absences. It is not academically sound to allow a student to continue after this many absences.

 Adding and Dropping Courses: A student may add a course with permission of the advisor through the second day of the semester. After that point, permission of the advisor and the instructor is needed in order to add a course. A student may drop a course at any time during the first eight weeks (or halfway through a summer session) of the semester by completing an official drop form, obtaining the signatures of the advisor and the instructor, and filing the form with the registrar. Students who stop attending class without officially dropping the course may receive a failing grade in the course.

 Withdrawal from a Course, Program, or the College: Emergency situations may arise after the no-penalty drop period whereby students must leave involuntarily. In this case, the student may withdraw from the course by completing a withdrawal form. The student must secure the instructor's signature on the withdrawal form. This form must be completed and filed with the registrar. Students who are passing at the time of withdrawal may receive a grade of WP. Students who are failing at the time of withdrawal may receive a grade of FW. Students who stop attending class without officially withdrawing from the course may receive a failing grade in the course.

 Instructor-Initiated Drop or Withdrawal: An instructor may drop or withdraw a student from a course if the student stops attending class or the student exceeds the maximum number of allowed absences.

Course Schedule This is an overview of the plan of study for this semester. More specific details for each section of study will be distributed in class.

 Chapter 14 The Chemistry of Alkynes  Chapter 15 Dienes, Resonance, and Aromaticity  Chapter 16 The Chemistry of Benzene and Its Derivatives  Chapter 17 Allylic and Benzylic Reactivity  Chapter 18 The Chemistry of Aryl Halides, Vinylic Halides, and Phenols  Chapter 19 The Chemistry of Aldehydes and Ketones  Chapter 20 The Chemistry of Carboxylic Acids  Chapter 21 The Chemistry of Carboxylic Acid Derivatives  Chapter 22 The Chemistry of Enolate Ions, Enols, and α, β–Unsaturated Carbonyl Compounds  Chapter 23 The Chemistry of Amines  Chapter 24 Carbohydrates  Chapter 26 Amino Acids, Peptides, and Proteins

CHEM 3351, FALL 2012 Page 4 of 7 Homework We will be using Sapling Learning for our online homework. Sapling's chemistry questions are delivered in a web browser to provide real-time grading, response-specific coaching, improvement of problem-solving skills, and detailed answer explanations. Dynamic answer modules enable one to interact with 3D models and figures, utilize drag-and-drop synthetic routes, and draw chemical structures - including stereochemistry and curved arrows. Altogether, Sapling is cheaper than a tutor, provides more value than a solutions manual, and goes beyond a mere assessment exercise to give a learning experience. Instructions: 1. Go to http://saplinglearning.com 2a. If you already have a Sapling Learning account, log in then skip to step 3. 2b. If you have Facebook account, you can use it to quickly create a SaplingLearning account. Click "create account" located under the username box, then click "Login with Facebook". The form will auto-fill with information from your Facebook account (you may need to log into Facebook in the popup window first). Choose a password and timezone, accept the site policy agreement, and click "Create my new account". You can then skip to step 3. 2c. Otherwise, click "create account" located under the username box. Supply the requested information and click "Create my new account". Check your email (and spam filter) for a message from Sapling Learning and click on the link provided in that email. 3. Find the course (University of Colorado, Boulder-CHEM 3371-Spring16-YIN) in the list (listed by school, course, semester and instructor) and click the link. 4. Select a payment option and follow the remaining instructions.  Once you have registered and enrolled, you can log in at any time to complete or review your homework assignments.  During sign up - and throughout the term - if you have any technical problems or grading issues, send an email to [email protected] explaining the issue. The Sapling support team is almost always more able (and faster) to resolve issues than your instructor and TAs.  To optimize your Sapling Learning experience, please keep your internet browser and Flash player up to date and minimize the use of RAM-intensive programs/websites while using Sapling Learning.

CHEM 3351, FALL 2012 Page 5 of 7 Syllabus Statements

Accommodation For Disabilities CU-Boulder recently underwent an investigation from the US Department of Justice regarding campus- wide accessibility. All faculty assume responsibility for ensuring that their individual courses and content are accessible to all students. If possible, utilize principles of Universal Design when creating new courses; otherwise, make appropriate alterations to existing material to accommodate students who require assistance. You may contact our Universal Instructional Design Consultant on the Academic Technology Design Team in the Office of Information Technology for more information by calling 303- 735-4357 (5-HELP).

The Boulder Provost’s Disability Task Force Recommended Syllabus Statement: If you qualify for accommodations because of a disability, please submit to your professor a letter from Disability Services in a timely manner (for exam accommodations provide your letter at least one week prior to the exam) so that your needs can be addressed. Disability Services determines accommodations based on documented disabilities. Contact Disability Services at 303-492-8671 or by e-mail at [email protected]. If you have a temporary medical condition or injury, see Temporary Injuries guidelines under the Quick Links at the Disability Services website and discuss your needs with your professor.

Religious Holidays It is the responsibility of every instructor to explain clearly his or her procedures about absences due to religious observances in the course syllabus so that all students are fully informed, in writing, near the beginning of each semester’s classes. Campus policy regarding religious observances states that faculty must make reasonable accommodation for them and in so doing, be careful not to inhibit or penalize those students who are exercising their rights to religious observance. Faculty should be aware that a given religious holiday may be observed with very different levels of attentiveness by different members of the same religious group and thus may require careful consideration to the particulars of each individual case. For more information on the religious holidays most commonly observed by CU-Boulder students consult the online interfaith calendar.

Recommended Religious Observances Syllabus Statement: Campus policy regarding religious observances requires that faculty make every effort to deal reasonably and fairly with all students who, because of religious obligations, have conflicts with scheduled exams, assignments or required attendance. See campus policy regarding religious observances for full details.

Classroom Behavior Faculty and students should be aware of the campus Classroom and Course-Related Behavior policy which describes examples of unacceptable classroom behavior and provides information on how to handle such circumstances should they arise. Faculty are encouraged to address the issue of classroom behavior in the syllabus, and to understand their professional rights and duties.

Recommended Classroom Behavior Syllabus Statement: Students and faculty each have responsibility for maintaining an appropriate learning environment. Those who fail to adhere to such behavioral standards may be subject to discipline. Professional courtesy and sensitivity are especially important with respect to individuals and topics dealing with differences of race, color, culture, religion, creed, politics, veteran’s status, sexual orientation, gender, gender identity and gender expression, age, disability, and nationalities. Class rosters are provided to the instructor with the student's legal name. I will gladly honor your request to address you by an alternate name or gender pronoun. Please advise me of this preference early in the semester so that I may make appropriate

CHEM 3351, FALL 2012 Page 6 of 7 changes to my records. For more information, see the policies on classroom behavior and the student code.

Discrimination And Harassment The University of Colorado Boulder (CU-Boulder) is committed to maintaining a positive learning, working, and living environment. CU-Boulder will not tolerate acts of sexual misconduct, discrimination, harassment or related retaliation against or by any employee or student. CU’s Sexual Misconduct Policy prohibits sexual assault, sexual exploitation, sexual harassment, intimate partner abuse (dating or domestic violence), stalking or related retaliation. CU-Boulder’s Discrimination and Harassment Policy prohibits discrimination, harassment or related retaliation based on race, color, national origin, sex, pregnancy, age, disability, creed, religion, sexual orientation, gender identity, gender expression, veteran status, political affiliation or political philosophy. Individuals who believe they have been subject to misconduct under either policy should contact the Office of Institutional Equity and Compliance (OIEC) at 303-492-2127. Information about the OIEC, the above referenced policies, and the campus resources available to assist individuals regarding sexual misconduct, discrimination, harassment or related retaliation can be found at the OIEC website.

Honor Code The Boulder campus has an Academic Integrity Policy and a student Honor Code; individual faculty members are expected to familiarize themselves with its tenets and follow the approved procedures should violations be perceived. The campus has been working diligently to make this process work better and to provide guidance on ‘gray areas’ to be helpful to both faculty and students at the Honor Code website.

All students enrolled in a University of Colorado Boulder course are responsible for knowing and adhering to the academic integrity policy of the institution. Violations of the policy may include: plagiarism, cheating, fabrication, lying, bribery, threat, unauthorized access, clicker fraud, resubmission, and aiding academic dishonesty. All incidents of academic misconduct will be reported to the Honor Code Council ([email protected]; 303-735-2273). Students who are found responsible of violating the academic integrity policy will be subject to nonacademic sanctions from the Honor Code Council as well as academic sanctions from the faculty member. Additional information regarding the academic integrity policy can be found at http://honorcode.colorado.edu.

CHEM 3351, FALL 2012 Page 7 of 7