Hellenic Accreditation System

Annex to the G1/4 Certificate No. 889-2

SCOPE of ACCREDITATION of the Clinical Laboratory of IN VITRO LABS S.A., Private Diagnostic Laboratories of Biotechnology

Materials/Product Types of test/Properties measured Applied methods/Techniques used s tested

Biochemical Tests

Blood serum Determination of 55 parameters Automated immune-biochemical analyzer ABBOTT Architect ci8200* 1. Β2 microglobulin (B2M) Turbidimetric with polystyrene latex particles 2. C reactive protein (CRP) Turbidimetric with polystyrene latex particles 3. Complement C3 Immunoturbidimetric 4. Complement C4 Immunoturbidimetric 5. Immunoglobulin Α (IgA) Immunoturbidimetric 6. Immunoglobulin G (IgG) Immunoturbidimetric 7. Immunoglobulin Μ (IgM) Immunoturbidimetric 8. Antistreptolysin O, (ASO) Turbidimetric with polystyrene latex particles 9. Rheumatoid Factor (RF) Turbidimetric with polystyrene latex particles 10.Transferrin (TRF) Immunoturbidimetric 11.Ceruloplasmin (CER) Immunoturbidimetric 12.Copper (Cu) Colorimetric (Dibr-PAESA) 13.Alanine aminotransferase (ALT/SGPT) IFCC, without P-5'-P 14.Aspartate aminotransferase (AST/SGOT) IFCC, without P-5'-P 15.Lactate dehydrogenase (LDH) IFCC, lactate to pyruvate 16.Haptoglobin (HPT) Immunoturbidimetric 17. Cholesterol (CHOL) Enzymatic reaction 18. Triglycerides (TRIG) Enzymatic reaction with Glycerol Phosphate Oxidase 19.Total Bilirubin (TBil) Diazonium Salt 20.Cholesterol HDL Enzymatic reaction with Accelerator Selective Detergent

of 12 Annex G1/4 to the Certificate ESYD No. 889-2 01.03.2016 Materials/Product Types of test/Properties measured Applied methods/Techniques used s tested 21.Cholesterol LDL Enzymatic reaction, Measured with Liquid Selective Detergent 22. Iron (Fe) Colorimetric assay with Ferene Blood serum 23. Albumin (ALB) Colorimetric assay with Bromcresol (continued) Purple 24. Total Protein (TP) Biuret Method 25.Alkaline phosphatase (ALP) Colorimetric assay with Para- nitrophenyl Phosphate 26.Creatine kinase (CK) Colorimetric assay with N-acetyl-L- cysteine (NAC) 27.Gamma-glutamyl trasferase (γ-GT) Enzymatic reaction with L-gamma- glutamyl-3-carboxy-4-nitroanilide Substrate 28. Lipase (LIP) Enzymatic reaction with Quinone Dye 29. Immunoglobulin E (IgE) Turbidimetric with polystyrene latex particles 30. Lithium (Li) Colorimetric assay with porphyrin 31. Creatine kinase MB isoenzyme- activity (CK- IFCC / Immunosuppression MB activity) 32. Amylase (AMYL) Enzymatic kinetic with CNPG3 Substrate 33. Chloride (Cl) Indirect, with ion-selective electrode diluted potentiometry 34. Magnesium (Mg) Enzymatic with isocitrate dehydrogenase 35.Phosphorus (P) Photometric with Phosphomolybdenic Acid 36. Sodium (Na) Indirect, with ion-selective electrode diluted potentiometry 37. Potassium (K) Indirect, with ion-selective electrode diluted potentiometry 38. Uric acid (Ua) Colorimetric enzymatic with uricase 39. Glucose (GLU) Colorimetric assay with Hexokinase /G-6- PDH 40. Urea (UREA) Urease Method 41. Creatinine (CREA) JAFFE Method Kinetic Alkaline Picrate 42. Calcium (Ca) Colorimetric assay with Arsenazo III Urine 43. Total Protein Urine (PT-UR) Turbidimetric with chloride benzethonium 44. Microalbumin Urine (MALB-UR) Immunoturbidimetric 45. Amylase (AMYL) Enzymatic kinetic with CNPG3 Substrate 46. Chloride (Cl) Indirect, with ion-selective electrode diluted potentiometry 47. Magnesium (Mg) Enzymatic with isocitrate dehydrogenase 48.Phosphorus (P) Photometric with Phosphomolybdenic Acid 49. Sodium (Na) Indirect, with ion-selective electrode diluted potentiometry 50. Potassium (K) Indirect, with ion-selective electrode diluted potentiometry 51. Uric acid (Ua) Colorimetric enzymatic with uricase 52. Glucose (GLU) Colorimetric assay with Hexokinase /G-6- PDH 53. Urea (UREA) Urease Method 54. Creatinine (CREA) JAFFE Method Kinetic Alkaline Picrate 55. Calcium (Ca) Colorimetric assay with Arsenazo III Determination of 2 parameter Cryoscopic Osmometer Osmomat 030* Blood serum 1. Serum Osmolality (OSMOL) Measurement of osmolality with Urine 2. Urine Osmolality (OSMOL-UR) Cryoscopic Osmometer

of 12 Annex G1/4 to the Certificate ESYD No. 889-2 01.03.2016 Materials/Product Types of test/Properties measured Applied methods/Techniques used s tested

Serum Protein Electrophoresis

Blood serum Determination of 5 parameters Automated Electrophoresis System SEBIA Capillarys 1. Albumin (ALB) Capillary Electrophoresis 2. Alfa1 globulins (A1) 3. Alfa2 globulins (A2) 4. Beta globulins (B) 5. Gamma globulins (G)

Test for detection of monoclonal proteins

Blood serum Detection of 1 parameter Electrophoresis apparatus semiautomatic multivariate system HYDRASYS FOCUSING * 1. Genre / type of monoclonal protein Electrophoresis / immunofixation

Toxicology Tests

Urine Determination of 7 parameters Automated immune-biochemical analyzer ABBOTT Architect ci8200* 1. Amphetamines (AMPH) Enzyme Immunoassay 2. Cocaine (COC) 3. Cannabinoids (THC) 4. Opiates (OPI) 5. Barbiturates (BARB) 6. Benzodiazepines (BENZO) 7. Ethanol (ETH) Kinetic Enzymatic with Alcohol Dehydrogenase

Immunochemical Tests

Blood serum Determination of 13 parameters Automated immunochemical analyzer ADVIA CENTAUR XP* 1. Cancer antigen Ca125 Chemiluminescence 2. Cancer antigen Ca15-3 3. Cancer antigen Ca 19-9 4. Carcinoembryonic antigen (CEA) 5. Alpha-fetoprotein (A-FP) 6. Free Prostate-specific antigen (Free-PSA) 7. Prostate-specific antigen (PSA) 8. C- peptide (C-Pept) 9. Insulin (INS) 10. Parathormone (PTH) 11. Prolactin (PRL) 12. Cortisol (CORT) Urine 13. Cortisol(CORT-UR) Blood serum Determination of 37 parameters Automated immune-biochemical analyzer ABBOTT Architect ci8200* Page 3 of 12 Annex G1/4 to the Certificate ESYD No. 889-2 01.03.2016 Materials/Product Types of test/Properties measured Applied methods/Techniques used s tested 1. B chorionic gonadotropin (B-HCG) Chemiluminescent Microparticle 2. Carbamazepine (CARB) Immunoassay (CMIA) 3. Digoxin (DIGOX) 4. Phenobarbital (PHENO) 5. Phenytoin (PHENYNT) 6. Valproic acid (VPA) 7. Theophylline (THEO) 8. Dehydroepiandrosterone –sulphate (DHEA-S) 9. Sex hormone-binding globulin (SHBG) 10. Free Triidothyronine (Free T3) 11. Free Thyroxin (Free-T4) 12. Triidothyronine total (T3) 13. Thyroxin total (Τ4) 14. Thyrotropin Hormone (TSH) 15. Ferritin (Ferr) 16. Follate Acid (FOL) 17. Vitamin B12 18. 25-hydroxy vitamin D (25-OH-Vit D) 19. Estradiol (O2) 20. Follicle Stimulating Hormone (FSH) 21. Luteinizing Hormone (LH) 22. Progesterone (PRG) 23. Testosterone (Testo) 24. B type natriuretic peptide (BNP) 25. Troponin I (TROP I) 26. Creatine kinase MB isoenzyme mass (CK-MB mass) 27. Myoglobin (MYO) 28. Toxoplasma IgG antibodies (TOXO IgG) 29. Toxoplasma IgM antibidies (TOXO IgM) 30. Rubella virus IgG antibodies (Rubella IgG) 31. Rubella virus IgM antibodies (Rubella IgM) 32. Cytomegalovirus IgG antibodies (CMV IgG) 33. Cytomegalovirus IgM antibodies (CMV IgM) 34. Hepatitis C IgG antibodies (Anti-HCV) 35. Human immunodeficiency virus type 1 & 2 (HIV-1 & 2) 36. Hepatitis B virus surface antigen (HBsAg) 37. Hepatitis B virus core total antibodies (HBcAb) Determination of 2 parametres Automated immunochemical analyzer Immulite 2000 XPi*

1. Calcitonin (CT) Chemiluminescence

Blood Plasma 2. Adrenocorticotropic hormone (ACTH) (EDTA) Blood serum Determination of 1 parameter Automated immunochemical analyzer Immulite 2000* 1. Growth hormone (HGH) Chemiluminescence

Hematological Tests

of 12 Annex G1/4 to the Certificate ESYD No. 889-2 01.03.2016 Materials/Product Types of test/Properties measured Applied methods/Techniques used s tested Whole blood Determination of 10 parameters Automated Hematological (EDTA) analyzersABBOTT Cell Dyn 3700* 1. Ηematocrit (HCT) Calculative from RBC and MCV 2. Ηemoglobin (Hb) Colorimetric 3. Μean corpuscular hemoglobin (MCH) Calculative from HGB and RBC 4. Μean corpuscular hemoglobin concentration Calculative from HGB and HCT (MCHC) 5. Μean corpuscular volume (MCV) Change in Electrical impedance 6. Mean platelet volume (MPV) 7. Platelets (PLT) 8. Red Cell Distribution Width (RDW) 9. Red Cells (RBC) 10. White Cells (WBC) Change in Electrical impedance and visual assessment Determination of 10 parameters Automated Hematological analyzer ROCHE SYSMEX XT-1800i * 1. Ηematocrit (HCT) Calculative from RBC and MCV 2. Ηemoglobin (Hb) Colorimetric 3. Μean corpuscular hemoglobin (MCH) Calculative from HGB and RBC 4. Μean corpuscular hemoglobin concentration Calculative from HGB and HCT (MCHC) 5. Μean corpuscular volume (MCV) Calculative from RBC and HCT 6. Mean platelet volume (MPV) Change in Electrical impedance 7. Platelets (PLT) 8. Red Cell Distribution Width (RDW) 9. Red Cells (RBC) 10. White Cells (WBC) Flow cytometry and visual assessment Determination of 1 parameter Chromatographic analyzer VARIANT II TURBO Bio-Rad*

1. Determination of glycated hemoglobin A1c HPLC (ion exchange High-

(HbA1C ) performance chromatography)

Clotting-Hemostasis Tests

Whole blood Determination of 8 parameters Clotting analyzer STAGO STAR (CITRATE) EVOLUTION * 1. Activated partial thromboplastin time (aPTT) Clotting 2. Prothrombin time (Pt) Clotting 3. Prothrombin time international normalized ratio Clotting (Pt INR) 4. Antithrombin (ATIII) Colorimetric with synthetic substrate C BS 61.50 5. Fibrinogen (FIBR) Clotting with excess of Thombin according to Clauss method 6. Protein C activity (PROT C) Colorimetric with synthetic substrate C BS 42.46 7. Free protein S antigen (Free S) Turbidimetric with polystyrene latex 8. D fibrin fragments (D-Dimers) particles

Immunological Tests

of 12 Annex G1/4 to the Certificate ESYD No. 889-2 01.03.2016 Materials/Product Types of test/Properties measured Applied methods/Techniques used s tested Blood serum Determination of 1 parameter Biorad Immunofluorescence PhD System* 1.Antinuclear antibodies (ANA) Immunofluorescence IFA with cellular substrate HEP-2 Determination of 6 parameters Automated immunochemical analyzer LIASON DIASORIN* 1.Antibodies against double-stranded DNA (ds Chemiluminescence DNA) 2. Antibodies against Extractable nuclear antigens ENA (SSA, SSB, RNP, SM, SCL-70, Jo1, Centromere) 3. Herpes Ι IgG antibodies (HSV I IgG) 4. Herpes ΙΙ IgG antibodies (HSV ΙΙ IgG) 5.Anti-cardiolipin IgG antibodies (aCL IgG) 6.Anti-cardiolipin IgM antibodies (aCL IgM) Determination of 2 parameters Automated immunochemical analyzer ELISA EUROIMMUNE* 1. Anti-beta-2-glycoprotein I IgG antibodies ELISA (aβ2GPI IgG) 2. Anti-beta-2-glycoprotein I IgM antibodies IgM (aβ2GPI IgM)

Molecular Genetics

Peripheral Blood Detection of 36 mutations of the cystic fibrosis Manufacturer’s kit INNO-LiPA transmembrane regualtor gene (CFTR) and 3 CFTR19 and INNO-LiPA CFTR17 polymorphisms at intron 8: (INNOGENETICS)* Polymerase Chain Reaction (PCR) with the use of the thermal cycler MASTER 1. F508del 21. 3849+10kbC→T CYCLER W/O GRADIENT 2. G542X 22. 2183AA→G EPPENDORFF and reverse dot blot 3. N1303K 23. 394delTT 4. W1282X 24. 2789+5G→A 5. G551D 25. 3659delC 6. 1717-1G→A 26. R1162X 7. R553X 27. R117H 8. CFTRdele2,3(21kb) 28. R334W 9. I507del 29. R347P 10. 711+1G→T 30. G85E 11. 3272-26A→G 31. 1078delT 12. 3905insT 32. 2143delT 13. R560T 33. A455E 14. 1898+1G→A 34. E60X 15. S1251N 35. 2184delA 16. I148T 36. 711+5G→A 17. 3199del6 T Polymorphisms at intron 18. 3120+1G→A 8: 19. Q552X 37. 5T 20. 621+1G→T 38. 7T 39. 9T

Peripheral Blood Detection of ΔF508del mutation of the cystic Manufacturer’s kit with Real Time fibrosis transmembrane regualtor gene (CFTR) PCR (Primer Design) with the use of the Real Time thermal cycler STRATAGENE MX3000P Peripheral Blood Detection of HLA B-27 Manufacturer’s kit with SSP-PCR (One Lambda) with the use of thermal cycler MASTER CYCLER W/O GRADIENT EPPENDORFF and visualization of the existence of amplification product Page 6 of 12 Annex G1/4 to the Certificate ESYD No. 889-2 01.03.2016 Materials/Product Types of test/Properties measured Applied methods/Techniques used s tested

Determination of allergens

Blood serum Determination of 191 allergens (Specific Automated immunochemical immunoglobulin IgE - RAST) analyzer Immulite 2000* ANTHOXANTHUM ODORATUM, Chemiluminescence 1. g1 SWEET VERNAL GRASS CYNODON DACTYLON, 2. g2 BERMUDA GRASS DACTYLIS GLOMERATA, 3. g3 ORCHARD GRASS FESTUCA ELATIOR, MEADOW 4. g4 FESCUE 5. g5 LOLIUM PERENNE, RYE-GRASS PHLEUM PRATENSE, TIMOTHY 6. g6 GRASS PHRAGMITES COMMUNIS, 7. g7 COMMON REED POA PRATENSIS, MEADOW 8. g8 GRASS, KENTUCKY BLUE AGROSTIS STOLONIFERA, RED 9. g9 TOP, BENTGRASS SORGHUM HALEPENSE, 10. g10 JOHNSON GRASS BROMUS ARVENSIS, BROME 11. g11 GRASS SECALE CEREALE, 12. g12 CULTIVATED RYE GRASS HOLCUS LANATUS, VELVET 13. g13 GRASS AVENA SATIVA, CULTIVATED 14. g14 OAT GRASS TRITICUM SATIVUM, 15. g15 CULTIVATED WHEAT GRASS PASPALUM NOTATUM, BAHIA 16. g17 GRASS ELYMUS TRITICOIDES, WILD 17. g70 RYE GRASS PHALARIS CANARIENSIS, 18. g71 CANARY GRASS 19. g202 CULTIVATED CORN, ZEA-MAYS AMBROSIA ELATIOR, COMMON 20. w1 RAGWEED SHORT AMBROSIA PSILOTACHYA, 21. w2 WESTERN RAGWEED AMBROSIA TRIFIDA, GIANT 22. w3 RAGWEED FRANSERIA ACANTHICARPA, 23. w4 FALSE RAGWEED ARTEMISIA ABSINTHIUM, 24. w5 WORMWOOD, SAGEBRUSH ARTEMISIA VULGARIS, 25. w6 MUGWORT 26. w7 CRYSANTHEMUM LEUCANTHEMUM, MARGUERITE, OX-EYE DAISY

of 12 Annex G1/4 to the Certificate ESYD No. 889-2 01.03.2016 Materials/Product Types of test/Properties measured Applied methods/Techniques used s tested TARAXACUM OFFICINALIS, 27. w8 DANDELION PLANTAGO LANCEOLATA, 28. w9 PLANTAIN CHENOPODIUM ALBUM, 29. w10 LAMB’S QUARTERS SALSOLA KALI, SALTWORT, 30. w11 RUSSIAN THISTLE SOLIDAGO VIRGAUREA, 31. w12 GOLDEN ROD XANTHIUM COMMUNE, 32. w13 COCKLEBUR AMARANTHUS RETROFLEXUS, 33. w14 COMMON PIGWEED ATRIPLEX LENTIFORMIS, 34. w15 SCALE, LENSCALE IVA CILIATA, ROUGH 35. w16 MARSHELDER RUMEX ACETOSELLA, SHEEP 36. w18 SORREL PARIENTARIA OFFICINALIS, 37. w19 WALL PELLITORY 38. w20 URTICA DIOICA, NETTLE PARIENTARIA JUDAICA, WALL 39. w21 PELLITORY ACER NEGUNDO, BOX-ELDER, 40. t1 MAPLE 41. t2 ALNUS URCANA, GREY ALDER BETULA VERRUCOSA, 42. t3 COMMON SILVER BIRCH CORYLUS AVELLANA, 43. t4 HAZELNUT FAGUS SILVATICA, AMERICAN 44. t5 BEECH MOUNTAIN CEDAR, JUNIPERUS 45. t6 SPP. 46. t7 QUERCUS ALBA, OAK 47. t8 ULMUS AMERICANA, ELM 48. t9 OLEA EUROPEA, OLIVE JUGLANS CALIFORNICA, 49. t10 WALNUT PLATANUS ACERIFOLIA, 50. t11 MAPLE LEAF SYCAMORE 51. t12 SALIX ALBA, WILLOW POPULUS SPP., POPLAR, 52. t14 COTTONWOOD FRAXINUS EXCELSIOR, WHITE 53. t15 ASH 54. t16 PINUS SILVESTRIS, WHITE PINE 55. t18 EUCALYPTUS SPP. 56. t19 ACACIA SPP. CUPRESSUS SEMPERVIRENS, ITALIAN/MEDITERRANEAN/FU 57. t23 NERAL CYPRESS 58. t37 WHITE BALD CYPRESS 59. t70 MORUS ALBA/MULBERRY

of 12 Annex G1/4 to the Certificate ESYD No. 889-2 01.03.2016 Materials/Product Types of test/Properties measured Applied methods/Techniques used s tested CASUARINA EQUISETIFOLIA, 60. t73 AUSTRALIAN PINE 61. t210 PRIVET, LIGUSTRUM VULGARE DERMATOPHAGOIDES PTERONYSSINUS (HOUSE DUST 62. d1 MITE) DERMATOPHAGOIDES 63. d2 FARINAE (FLOUR MITE) DERMATOPHAGOIDES 64. d3 MICROCERAS 65. d71 LEPIDOGLYPHUS DESTRUCTOR 66. d72 TYROPHAGUS PUTRESCENTIAE 67. d73 GLYCYPHAGUS DOMESTICUS EYROGLYPHUS MAYNEI 68. d74 (HOUSE DUST MITE) 69. h1 GREER LABS 70. h2 HOLLISTER-STIER LABS 71. m1 PENICILLIUM NOTATUM 72. m2 CLADOSPORIUM HERBARUM 73. m3 ASPERGILLUS FUMIGATUS 74. m4 MUCOR RACEMOSUS 75. m5 CANDIDA ALBICANS ALTERNARIA ALTERNATA 76. m6 (TENUIS) 77. m207 ASPERGILLUS NIGER 78. m312 ASPERGILLUS CLAVATUS 79. p1 ASCARIS 80. k20 WHOOL (SHEEP’S/LAMB’S) 81. k74 SILK (Bombyx mori) 82. k82 LATEX, HEVEA BRAZILIENSIS 83. k83 COTTON SEED 84. o1 COTTON 85. f1 EGG WHITE 86. f75 EGG YOLK 87. f232 OVALBUMIN 88. f233 OVOMUCOID 89. f245 EGG 90. f2 COW'S MILK 91. f67 PARMESAN CHEESE 92. f76 A-LACTALBUMIN 93. f77 B-LACTOGLOBULIN 94. f78 CASEIN 95. f81 CHEESE CHEDDAR TYPE 96. f82 CHEESE MOLD-TYPE 97. f170 SWISS CHEESE 98. f231 MILK BOILED 99. f325 SHEEP’ S MILK 100. f360 YOGHURT 101. f409 GOAT’ S MILK 102. f4 WHEAT FLOUR 103. f5 RYE FLOUR 104. f6 BARLEY FLOUR 105. f7 OAT FLOUR 106. f8 CORN FLOUR 107. f9 RICE 108. f10 SESAME SEED Page 9 of 12 Annex G1/4 to the Certificate ESYD No. 889-2 01.03.2016 Materials/Product Types of test/Properties measured Applied methods/Techniques used s tested 109. f11 BUCKWHEAT FLOUR 110. f79 GLUTEN, GLIADIN 111. f33 ORANGE 112. f44 STRAWBERRY 113. f49 APPLE 114. f84 KIWI FRUIT 115. f92 BANANA 116. f94 PEAR 117. f95 PEACH 118. f96 AVOCADO 119. f237 APRICOT 120. f242 CHERRY 121. f259 GRAPE 122. f13 PEANUT 123. f17 HAZEL NUT BRAZIL NUT (from Bertholletia 124. f18 excelsa) 125. f20 ALMOND 126. f36 COCONUT 127. f202 CASHEW NUT 128. f203 PISTACHIO NUT 129. f256 WALNUT 130. f12 GREEN PEA 131. f14 SOYA BEAN 132. f15 WHITE BEAN 133. f25 TOMATO 134. f31 CARROT 135. f35 POTATO 136. f47 GARLIC 137. f48 ONION 138. f212 MUSHROOM 139. f214 SPINACH 140. f235 LENTIL 141. f26 PORK 142. f27 BEEF 143. f83 CHICKEN MEAT 144. f88 MUTTON / LAMB 145. f213 RABBIT MEAT 146. f284 TURKEY MEAT 147. f3 CODFISH 148. f23 CRAB 149. f24 SHRIMP 150. f37 BLUE MUSSEL 151. f40 TUNA 152. f41 SALMON 153. f59 OCTOPUS 154. f61 SARDINE (S.PILCHARDUS) 155. f65 PERCH 156. f80 LOBSTER 157. f207 CLAM 158. f258 SQUID 159. f45 BAKER'S YEAST 160. f89 MUSTARD 161. f90 MALT 162. f93 CACAO

of 12 Annex G1/4 to the Certificate ESYD No. 889-2 01.03.2016 Materials/Product Types of test/Properties measured Applied methods/Techniques used s tested 163. f105 CHOCOLATE 164. f221 COFFEE 165. f222 TEA 166. f247 HONEY 167. e1 CAT EPITHELIUM - DANDER 168. e2 DOG EPITHELIUM 169. e3 HORSE DANDER 170. e4 COW DANDER 171. e5 DOG DANDER 172. e71 MOUSE EPITHELIUM 173. e80 GOAT EPITHELIUM 174. e81 SHEEP EPITHELIUM 175. e215 PIGEON FEATHERS 176. i1 APIS MELLIFERA, BEE VENOM 177. i2 WHITE FACED HORNET COMMON WASP/YELLOW 178. i3 JACKET VENOM 179. i4 PAPER WASP VENOM DOLICHOVESPULA 180. i5 ARENARIA/YELLOW HORNET VESPA CRABO/EUROPEAN 181. i75 HORNET BLATELLA GERMANICA, 182. i6 COCKROACH 183. i8 MOTH 184. i71 MOSQUITO 185. i73 CHIRONOMUS PLUMOSUS MEDITERRANEAN FLOUR 186. i203 MOTH 187. i204 HORSE FLY 188. c1 PENICILLIN G 189. c2 PENICILLIN V 190. c203 AMPICILLIN 191. c204 AMOXICILLIN Blood serum Determination of 17 allergens panels Automated immunochemical analyzer Immulite 2000* 1. GP1 Panel of grasses, flowering early (g3, Chemiluminescence g4, g5, g6, g8) 2. GP2 Panel of grasses, flowering early(g2, g5, g6, g8,g10, g17) 3. GP4 Panel of grasses, blooming late(g1, g5, g7, g12) 4. WP3 Weed panel (w6, w9, w10, w12, w20) 5. TP4 Tree pollen panel (t7, t8, t11, t12, t14) 6. HP1 Homemade dust Ppanel (h1, d1, d2, i6) 7. MP1 Fungi panel (m1, m2, m3, m5, m6) 8. IP8 Inhalant panel (d1, e1, e5, g6, g12, m2, t3, w6) 9. IP10 Inhalant panel (t9, t11, t23, w9, w19) 10.FP5 Food panel (f11, f2, f3, f4, f13, f14)

of 12 Annex G1/4 to the Certificate ESYD No. 889-2 01.03.2016 Materials/Product Types of test/Properties measured Applied methods/Techniques used s tested 11.FP15 Fruit panel (f33, f49, f92, f95) 12.FP1 Nuts panel (f13, f17, f18, f20, f36) 13.FP51 Vegetables and mustard panel (f25, f31, f35, f47, f89) 14.FP2 Fish and shellfish panel (f3, f24, f37, f40, f41) 15.EP70 Rodent panel (e6, e82, e84, e87, e88) 16.EP71 Panel of farm-birds feathers (e70, e85, e86, e89) 17.EP72 Panel of pet-birds feathers (e78, e891 e86201) *Reference to the commercial name of a specific analyzer/kit, refers to a specific analytical method and protocol

Site of assessment: Permanent premises, 9, Leventi str., 12132, Peristeri, Attiki, Greece. Approved signatories: E. Makri, K. Chatzantonaki, G. Zormpas, V. Kotsigiannis, R. Kaizer, M. Kechagia, A. Pavlos , K. Gkarelis, A. Charvalou, D. Dimitriadi.

This Scope of Accreditation replaces the previous one dated 20.04.2015. The Accreditation Certificate No. 889-2, to ELOT EN ISO 15189:2012, is valid until 15.10.2017.

Athens, March 01, 2016

Ioannis Sitaras Director of the Laboratories Accreditation Division

of 12 Annex G1/4 to the Certificate ESYD No. 889-2 01.03.2016