Zarins Vascular Biology Lab

Oscar J. Abilez

Address

Stanford University Zarins Vascular Biology Lab James H. Clark Center, E350 318 West Campus Drive Stanford, CA 94305-5431 (650) 725-5017 (tel) (650) 725-9082 (fax) [email protected]

Education Cornell University, New York, NY 1996-2002 M.D. University of Texas, Austin, TX 1987-1996 M.S. Graduate Work, Biomedical Engineering Post Baccalaureate Work B.S., Mechanical Engineering

Residency Stanford University, Stanford, CA 2002-2004 Resident, General Surgery Intern, General Surgery

Awards Cornell University, New York, NY Franklyn Ellenbogen Prize in Hematology/Oncology 2002 Student Leadership Award 2002 American Austrian Foundation/Max Kade Foundation Fellowship 2002 United States-European Medical Education Exchange Fellowship 2002 NIH NHLBI Predoctoral Research Training Fellowship 1999-2000 Lucille P. Markey Foundation Predoctoral Research Training Fellowship 1998-1999 NIH Molecular Mechanism of Neurological Disease Predoctoral Fellowship 1996-1997 CarboMedics, Inc., Austin, TX CarboMedics Manager Level Awards 1994-1996 University of Texas, Austin, TX Biomedical Engineering Merit Scholarship 1995 Pi Tau Sigma Mechanical Engineering Honor Society 1991 Engineering Honor Roll 1988-1991 Dean's List 1988-1991 General Motors Scholarship 1989 Haggar Foundation Scholarship 1989 Texas Achievement Award 1987-1992 Honors Colloquium Scholarship 1987 Junction High School, Junction, TX Valedictorian 1987 Oscar J. Abilez

Research Interests Tissue engineering, stem cell biology

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Research Experience Stanford University, Stanford, CA 7/04-present Postdoctoral Scholar Department of Surgery, Division of Vascular Surgery, Vascular Research Lab Advisor: Christopher Zarins, M.D.  Creating a bioreactor for dynamic cell and tissue culture  Using mouse embryonic stem cells to create a blood vessel Cornell University, New York, NY 1998-2000 Medical Student Research Fellow Department of Medicine, Division of Hematology & Oncology Advisor: Roy Silverstein, M.D.  Helped characterize the role of scavenger receptor CD36 in dendritic cell differentiation, migration, and antigen presentation  Helped develop a monoclonal antibody to the scavenger receptor CD36 Cornell University, New York, NY 1996-1997 Medical Student Research Fellow summers Department of Neuroscience Advisor: Robert Duvoisin, Ph.D.  Designed a DNA construct that coded for a fusion protein consisting of a metabotropic glutamate receptor and a green fluorescent protein (GFP) University of Texas, Austin, TX 1995-1996 Biomedical Engineering Graduate Student Advisor: Thomas Runge, M.D.  Evaluated the rheology of blood mixed with a perfluorocarbon- based artificial blood substitute

Professional Experience CarboMedics, Inc., Austin, TX 1993-1996 Engineering Specialist Supervisor: Andy Campbell, P.E.  Supported design and development of Pyrolytic® and tissue heart valve prostheses  Developed various manufacturing processes that utilized CO2 laser Eckerd Drug Store, Austin, TX 1992 Pharmacy Clerk Supervisor: Tol Wilhite  Stocked pharmaceutical items General Motors, Mesa, AZ 1991 Engineering Co-op Student Supervisor: Karl Schmitz, P.E.  Tested vehicles at Desert Proving Ground General Motors, Shreveport, LA 1989-1990 Engineering Co-op Student Supervisor: Larry Johnson, P.E.  Developed manufacturing processes at an automobile assembly plant Hill Country Hydro, Austin, TX 1988 Salesperson Supervisor: Gilbert Escobar  Sold Rainbow® vacuum cleaners

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Teaching Experience Stanford University, Stanford, CA 2004 Surgery Resident  Taught suturing and knot tying classes for medical students Cornell University, New York, NY 2000 Mentor, Cornell Science Challenge  Led 7th and 8th graders through a semester long science project Cornell University, New York, NY 1997 Teaching Assistant, Brain & Mind Course  Prepared prosections and taught head and neck anatomy University of Texas, Austin, TX 1993 Grader, Design of Thermal-Fluid Systems  Graded homework, projects, and exams House of Tutors, Austin, TX 1992-1993 Tutor  Tutored various subjects and published organic chemistry notes

Volunteer Experience Cornell University, New York, NY 1996-1997 Volunteer  Adolescent Substance Abuse Program  High School Health Professions Recruitment and Exposure Program  Lenox Hill Community Center Holiday Party Brackenridge Hospital, Austin, TX 1992-1993 Volunteer  Emergency and Pediatric Departments

Technical Skills Southern blotting, northern blotting, western blotting, flow cytometry/FACS, immunohistochemistry, recombinant DNA work, fusion protein creation, GFP work, monoclonal antibody construction, cell and tissue culture, light microscopy, confocal microscopy, digital image processing, murine husbandry, product design, product prototyping, product validation and testing, computer-aided design, animal and human surgery

Inventions Abilez O, Stanford University. “Systems, Methods, and Apparatus Configurations Using Genetic Algorithms to Design Cells, Tissues, and Tissue Systems.” USA. 2004. (Disclosed to Stanford Office of Technology Licensing, Docket S04-293).

Abilez O, Stanford University. “Tools and Instruments with Locking Mechanism that Allows Both Left and Right Handed Use.” USA. 2004. (Disclosed to Stanford Office of Technology Licensing, Docket S04-303).

Abilez O, Zarins C, Stanford University. “Methods and techniques for creating in-situ biological structures by using autologous biological materials in combination with intra- or extra-corporeal bio-mechanical, bio-chemical, bio-electric, and bio-thermal conditioning.” USA. 2005. (Disclosed to Stanford Office of Technology Licensing, Docket S05-067).

Abilez O, Hochberg L, Vase A, Velan A, Stanford University. “Systems and methods for temporally regulating agent delivery to the central nervous system.” USA. 2005. (Disclosed to Stanford Office of Technology Licensing, Docket S05-105, Patent Pending, USPTO).

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Abstracts Abilez O, Berger D, Febbraio M, Silverstein R: Bone Marrow-Derived Cells from CD36 Null Mice are Less Efficient than Those Derived from Wild-Type Mice in the Phagocytosis of Apoptotic Cells. Molecular Biology of the Cell, Nov 1999, 10S:189a.

Presentations “The Design of a Bioreactor for Tissue Engineering Applications”. Abilez O. Cardiovascular Institute Presentation, Stanford, CA. Apr 01, 2005.

“Inguinal Hernia Repair”. Abilez O. Department of Surgery Core Course, Stanford, CA. Aug 19, 2003.

“Depression: A Case Report with a Comparative Analysis of German and American Health Care Delivery Systems”. Abilez O. United States-European Medical Education Exchange (US-EUMEE) Presentation Conference, New York, NY. May 15, 2002.

“A Proposal to Study Alcoholic Liver Cirrhosis.” Abilez O. United States-European Medical Education Exchange (US-EUMEE) Conference, Lund, Sweden. Nov 13-14, 2001.

“Renal Cell Carcinoma and Inferior Vena Cava Involvement”. Abilez O. Cornell Department of Urology Conference, New York, NY. May 18, 2001.

“Bone Marrow-Derived Cells from CD36 Null Mice are Less Efficient Than Those Derived from Wild-Type Mice in the Phagocytosis of Apoptotic Cells.” Abilez O, Berger D, Febbraio M, Silverstein R. Poster presented at the 39th American Society for Cell Biology Annual Meeting, Washington, DC. Dec 11-15, 1999.

Handbooks Nguyen T, Abilez O, et al., Eds. Pocket Scalpel (Stanford Surgery Resident Handbook). 2nd ed. Palo Alto; 2004.

Nguyen T, Abilez O, et al., Eds. Pocket Scalpel (Stanford Surgery Resident Handbook). 1st ed. Palo Alto; 2003.

Professional Organizations American Society of Artificial Internal Organs (ASAIO) 1995-2000 Biomedical Engineering Society (BMES) 1994-2000 American Medical Association (AMA) 1996-2000

Medical School Service Guild Planning Committee 1996-1997 New Student Orientation Committee 1996 Brain and Mind Course Planning Committee 1996 Basis of Disease Course Planning Committee 1996 Curriculum Student/Faculty Retreat 1997-1999 Spring Picnic Committee 1997-1998

Activities Medical School Class President 1996-1998 Stimson Surgical Society President 2000-2001 Medical School Executive Council Representative 1996-1998

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Running Golfing

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References Christopher K. Zarins, M.D. Chidester Professor of Surgery Chief, Division of Vascular Surgery Director, Vascular Research Lab Stanford University School of Medicine 300 Pasteur Dr, H-3642 Stanford, CA 94305-5642 (650) 725-7830 (phone) (650) 498-6044 (fax) [email protected]

Chengpei Xu, M.D., Ph.D. Co-Director, Vascular Research Lab Stanford University School of Medicine James H. Clark Center, E350, MC 5431 318 Campus Dr West Stanford, CA 94305-5431 (650) 725-2595 (phone) (650) 725-5092 (fax) [email protected]

Thomas M. Krummel, M.D. Emile Holman Professor Chair, Department of Surgery Stanford University School of Medicine Director, Surgical Innovation Program at Stanford Susan B. Ford Surgeon-in-Chief Lucile Packard Children's Hospital 701B Welch Rd, Suite 225 Stanford, CA 94305-5784 (650) 498-4292 (phone) (650) 725-3918 (fax) [email protected]

Roy L. Silverstein, M.D. Chair, Department of Cell Biology Lerner Research Institute Cleveland Clinic Foundation NC10 9500 Euclid Ave Cleveland, OH 44195 (216) 444-5220 (phone) (216) 444-9404 (fax) [email protected]