Curriculum Vitae s124

Bio-data (Curriculum vitae)

T.R. SHANTHA, LMP (University of Mysore), M.D (University of Calcutta, R.G. Kar Medical College), Ph.D. (Emory University School of Medicine), F.A.C.A, D.A.B.A, (Anesthesia), D.A.P.M, D.A.B.A.P.M (pain manage, USA), F.Z.S (Lon), F.R.M.S (Eng),

Home Address: 115 Bayberry Hills, McDonough, GA 30253. USA Email and Web: [email protected] ; www.3E-Technologies.com

Phone. 770-507-6565; Cell: 678-640-7705

Dr. T. R. Shantha was nominated for Nobel Prize for the year 2007 in Physiology and medicine for his discoveries made with Prof. Dr. G.H. Bourne on the membranes of the peripheral nervous system during his research carrier spanning 15 years at Emory University School of Medicine, Atlanta, GA. (Nomination for NP are not made posthumously)

(T. R. Shanthaveerappa, in previous publications)

Author of 7 books and more than 125 research papers in various scientific journals all over the world. Only scientist to publish 7 research papers in distinguished British Journal NATURE, as well as other journals such as Science, New England J Medicine and J. National. Cancer Inst., World health org Bul. J Cell Biology, J Anatomy, La Cellule, ZZ microscopic anatomy, Hishctochemie, Experimental Eye Research, American J. of physiology, Archives of ophthalmology, Anatomical record, American Journal of Anatomy, J of Anatomy (Lond), Anesthesiology, Anesthesia Analgesia, British J. Anesthesia, ) and many other international peer reviewed reputable research journals.

2007 September: Published an important article on “Unknown Health Risks of Inhalation Insulin” By T. R. Shantha, MD, PhD, FACA, Life Extension, September 2007 issue in USA (pp 78-83). This latest publication warns of the dangers of sing this expensive insulin resulting more cancers, polyps, exaggerated asthmatic attack and COPD, vocal cord nodules, oro-aero-upper digestive tack cancers, infections and other conditions. The carcinogenic and other ill effects may not show until decades of its use as we saw in Vioox, Avandia and other drugs use resulting early death. This research article may save thousands of lives by preventing the development of cancer. Pfizer company withdrew Exubera (inhalation insulin) from the market after publication of this article; taking a loss of 2.5 billion dollars. Many drug companies are considering this article as a warning regarding the development of Carcinogenic inhaled insulin.

Bio Data (CV) of Dr. T. R. Shantha 1 Sunday, October 12, 2008 Page 1 of 37 See page 2 and 3 documents of Nobel Prize Nomination

Medical, Book, computer software and Hardware Editor: The Inspirator International- Pacific Rim's largest circulation English magazine and Financial Services Advisor, a US bi monthly English publication with circulation of 90,000(T. R. (Shanthaveerappa, in previous publications).

Bio Data (CV) of Dr. T. R. Shantha 2 Sunday, October 12, 2008 Page 2 of 37 Married with six children: 2 sons are physicians (anesthesiologist and urologist), one daughter is per fusionist trained under Denton Cooley Texas Heart Institute in Houston, Jessica is in medical school in Atlanta, Erica is senior in UGA, and Lauren is Junior in Tuscaloosa, Alabama.

Education: Schools attended by T. R. Shantha

Bio Data (CV) of Dr. T. R. Shantha 3 Sunday, October 12, 2008 Page 3 of 37 Name of the School Place Year Degree Received 1 Primary School, Janthikolalu, 1940-1944 Primary School India 2 Middle School Chitradurga 1944-1948 Lower Secondary India School, LS 3 Government High School, Chitradurga 1949-1951 SSLC. 4 University Medical Bangalore 1951-1955 LMP (Physician- School India Licensed Medical Practice) 4 R.G. Kar Medical College Calcutta, 1956-1958 MD degree India 5 Emory University School Atlanta 1960-1962 PhD in Basic medical of Medicine Sciences, Major in Anatomy 6 Residency at anesthesia Atlanta, 1968-1979 Residency completion department at Emory certification to University School of practice anesthesia Medicine, Grady Hospital

Degrees and Fellowship bestowed

Degrees Conferred Years Conferred 1 LMP (University of Mysore) 1955 2 M.D (University of Calcutta), 1958 3 Ph.D. (Emory University School of Medicine), 1962 4 F.A.C.A,(Fellow of American Society of 1969 Anesthesia) 5 D.A.B.A, (Diplomat of American Society of 1972 Anesthesia) 6 D.A.B.A.P.M (Diplomat of American Society of 1992 Anesthesia) 7 D.A.P.M, (pain manage, USA), 1992 8 F.Z.S (Fellow of Zoological Society of London) 1965 (approximate) 9 F.R.M.S (Fellow of the Royal Microscopical 1965 (approximate) Society of England),

JOBS HELD BY DR. SHANTHA

# Job Description Years of jobs held

Bio Data (CV) of Dr. T. R. Shantha 4 Sunday, October 12, 2008 Page 4 of 37 1 Appointed by the Director of Medical Services and by from August 1958 to the Public Service Commission for the Government of August 1960 Mysore, Karnataka State, India, as assistant surgeon, and worked in various capacities. SDS Sanitarium, and Victoria Hospital, Bangalore. 2 Lecturer, Department of Anatomy, Bangalore Medical Till August 1960 College, University of Mysore. 3 Research fellow and graduate student in the Department September, 1960, and of Anatomy and Basic Medical Sciences, Emory received PhD in the University School of Medicine, Atlanta, Georgia. spring of 1962 4 During this period (September 1960 to June 1962) assigned to teach medical and dental students in Gross Anatomy, Neuroanatomy, and to conduct Histology laboratories. 5 Lecturer in Anatomy, Emory University, Department of From July 1962 Anatomy, Atlanta, Georgia: .Teaching Medical and Dental students 5 Assistant Professor of Anatomy, Associate Professor of From June 1964 to Ophthalmic Research, Neurohistochemistry and June 1965. Histology; Emory University School of Medicine, Atlanta, Georgia . Published 11 papers on the eye, discovered new membrane on nerves, and Arachnoid villi in the optic nerve of man and monkey. 6 Director of Neurohistochemistry, Yerkes Regional June 1965 to 1968. Primate Center, Emory University, Atlanta, and Published 4 books on the brain and Neurohistochemistry Papers. 7 Fellow in Department of Anesthesiology, Emory November 1968 to University School of Medicine, Atlanta, Georgia,). October 1970 (Residency Training) 8 Associate Professor, Department of Anesthesiology November 1970 to Yerkes Regional Primate Research Center, and 1972 Associate Professor of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia. Dr. T. R. Shantha was the first person to be appointed as Associate Professor in the history of Emory University after residency training. 9 Staff Anesthesiologist, Georgia Baptist Medical Center, 1972-1997 Atlanta, Georgia, 10 Staff Anesthesiologist, Columbus Medical Center, 1976 to 1987. Columbus, Georgia, and Worked 48 hours from Friday 5PM to Sunday 5PM for 10 years 11 Associate Chairman, Department of Anesthesiology, until 1988 Georgia Baptist Medical Center, Atlanta, Georgia. 12 Visiting Professor, J. J. M. Medical College, 1989-present Davanagere, Karnataka, India 13 Clinical Professor, Medical College of Georgia, 1990 -1997

Bio Data (CV) of Dr. T. R. Shantha 5 Sunday, October 12, 2008 Page 5 of 37 August, Georgia, 14 Medical Director, SouthEastern Pain Institute, (SEPI) 1990 to 1997 Georgia Baptist Medical Center of Atlanta,

16 Staff Member: Millennium Health Care,4370 George 2000-2003? town Sq. Atlanta, GA 30338, Avatar Cancer Center, 1867 Independent Sq, Atlanta, GA, 30338 17 Staff and Private Practice 2001-Present Integrated Medical Specialists Integrated Chemotherapy Specialist 115 Eagle Spring Dr, Stockbridge, GA.30381

Previously:

Personal Data: Children: Dr. T. R. Shantha is a proud father of 2 sons and 4 daughters. Two his sons are physicians practicing in Georgia and South Carolina, his daughter is PA working in Macon Medical center as per-fusionists helping cardiac patients. She was trained as cardiovascular per -fusionist trained under Famous heart surgeon Dr. Denton Cooley of Texas Heart Institute. One of his daughters (fourth child) is admitted to Morehouse Medical College for the class of 2007, and the fifth daughter is a premed student seeking medical admission, and the last daughter is perusing public relations and hospitality carrier in Atlanta, Galilean.

Dr. Shantha is a US Citizen

DISTINCTIONS AND AWARDS :

Nobel Prize Nomination: Dr. T. R. Shantha is nominated for Nobel Prize for the year 2007 in Physiology and medicine for his discoveries made on the membranes of the peripheral nervous system during his research carrier spanning 15 years at Emory University School of Medicine, Atlanta, GA. Even before this nomination; Comments were made by Nobel Laureates Such as Prof. Peter Medawar, that “Dr. T. R. Shantha and Dr. G.H. Bourne’s work on the membranes of the nervous system deserves Nobel Prize in Medicine” when they listened to the presentation of his work in distinguished Scientific assemblies all over the world.

Bio Data (CV) of Dr. T. R. Shantha 6 Sunday, October 12, 2008 Page 6 of 37 4. Awarded two first prizes from the Georgia Society of Anesthesiologists in 1969 and 1970 in an Anesthesia Residency essay competition on subjects concerned with Anesthesiology. (1. Pain: A Dilemma, 1969; 2. Reflexes in Anesthesia, 1970). 5. Listed in Who's Who in American Men of Science and in Outstanding Atlantan’s (Heritage publication, 1978-79) 6. Received A.M.A. Physician Recognition Award during 1970-1996. The latest one was for 3 years starting from 1997. 7. Declared Dr. Shantha day by DeKalb county Chief executive (CEO- Ms. Leona Levitan) and the county commissioners in honor of my contribution in research, humanitarian and philanthropic work in 1993. 8. Proclaimed honorary citizen by City of Atlanta, New Orleans, Knoxville, Topeka Kansas, Kansas City of Missouri, and Kentucky cornel etc. 9. He was selected as the distinguished physician and Scientist by American Association of Physicians from India (AAPI) and VSNA members in the year 2005. This association has 42000 physicians practicing in US. In the same year he was also awarded the distinguished service award by VSNA society of India.

PREVIOUSLY:

1. Clinical Professor: Department of Anesthesia, Medical College of Georgia, Augusta, GA 30912-2700 up to 1997, Associate professor Emory University School of Medicine, Medical Staff: Columbus Medical Center, Columbus, GA, Staff Anesthesiologist, Grady Memorial Hospital, 1970-1975 (some of it is voluntary free service) 2. Medical Director, Neuro Histochemistry Section, Yerkes Regional Primate Center of Emory University, Atlanta, GA. 3. Ex. Medical Director: Southeastern Pain Institute, (SEPI), at Georgia Baptist Medical Center, Atlanta, GA 4. Associate Chairman and staff Member, Department of Anesthesia, Georgia Baptist Medical Center (now Atlanta Medical Center) 353 Parkway, Atlanta, GA 30312 5. Staff Member: Millennium Health Care,4370 George town Sq. Atlanta, GA 30338, Avatar Cancer Center, 1867 Independent Sq, Atlanta, GA, 30338 Alternative Survival Medicine, Inc, Fountain of Youth Health Care Center, PC 6. Medical, Book, computer software and Hardware Editor: The Inspirator International-Pacific Rim's largest circulation English magazine and Financial Services Advisor, a US bi monthly English publication with circulation of 90,000 7. Editorial Board, Pain practice management magazine, 1998 8. Staff and Private practice: Integrated Medical Specialist, 2000-2005

Bio Data (CV) of Dr. T. R. Shantha 7 Sunday, October 12, 2008 Page 7 of 37 SCIENTIFIC SOCIETY AFFILIATIONS PREVIOUS AND NOW: Previous: Member of the Sigma Xi Society Member of the Southern Society of Anatomists of the U.S.A. Member of the International and American Histochemical Society Member of the American Association of Anatomist

Current , previous and some inactive : Fellow of the Zoological Society of London (F.Z.S.),Fellow of the Royal Microscopical Society of England (F.R.M.S.) Member of the American Society of Anesthesiologists, Member of the Medical Association of Georgia and Atlanta Member of the American Medical Association – Active to the present Member of the Georgia Society of Anesthesiologists and Southern Society of Anesthesiologists Member of the Greater Atlanta Society of Anesthesiologists Member of the Indian Medical Council Member of the American Academy of Pain Management Patron member and member: American Association of Physicians from India (AAPI AND GAPI,) American Association of Regional Anesthesia, Member of ACAM and A4M Life member and past-trustee of Atlanta chapter, Veerashaiva Samaj of North America Member: Under sea and Hyperbaric Medical Society. ) American Society of Clinical Oncology, (ASCO) 2003-present.

MEDICAL LICENSE:

License to Practice Medicine and Prescribe Controlled Substances: Licensed in state of Georgia in the year 1972 to practice medicine and surgery (No. 014721); India, in 1955-1958 (# 1971). Controlled Substance registration certificate, Schedule 2, 2N, 3, 3N, 4, 5, #. AS-30574 56.

E.C.F.M.G. Certification: Passed the examination given by the Education Council for Foreign Medical Graduates Board (E.C.F.M.G. Certificate No.63869, 1965

MEDICAL BOARD CERTIFICATIONS:

1. Fellow of the American College of Anesthesiologists, 1973, # 5780 (F.A.C.A) 2. Diplomat of the American Board of Anesthesiology, 1973, # 6106 (D.A.B.A.) Diplomat of the American Academy of Pain Management, 1992, #. 41208 (D.A.P.M) 3. Diplomat, Clinical Electro medical Research Academy, 1996, Certificate #. 7270 4. Diplomat of the American Board of Pain management, 1996, # 06106 5. Certified and Trained in Hyperbaric Medicine May 21, 1999 by the Hyperbaric Medicine Program of Palmetto Richland Memorial hospital. University of South Carolina, Columbia, SC

Experience:

1. Appointed by the Director of Medical Services and by the Public Service Commission for the Government of Mysore, Karnataka State, India, as assistant surgeon, and worked in various capacities from August 1958 to August 1960.

Bio Data (CV) of Dr. T. R. Shantha 8 Sunday, October 12, 2008 Page 8 of 37 2. Assistant Surgeon in thoracic surgery and tuberculosis unit in S.D.S Sanatorium; cardiology and ENT departments in Victoria Hospital. Both hospitals are attached to the University of Mysore for training physicians. 3. Lecturer, Department of Anatomy, Bangalore Medical College, University of Mysore. 4. Research fellow and graduate student in the Department of Anatomy and Basic Medical Sciences, Emory University School of Medicine, Atlanta, Georgia in September, 1960, and received PhD in the spring of 1962. 5. During this period (September 1960 to June 1962) assigned to teach medical and dental students in Gross Anatomy, Neuroanatomy, and to conduct Histology laboratories. 6. From July 1962, Lecturer in Anatomy, Emory University, Department of Anatomy, Atlanta, Georgia. 7. Assistant Professor of Anatomy form July 1963 to June 1964, Emory University, Department of Anatomy, Atlanta, 8. Assistant Professor of Anatomy, Associate Professor of Ophthalmic Research, Neurohistochemistry and Histology, Emory University School of Medicine, Atlanta, Georgia from June 1964 to June 1965. 9. Director of Neurohistochemistry, Yerkes Regional Primate Center, Emory University, Atlanta, June 1965 to 1968. 10. Fellow in Department of Anesthesiology, Emory University School of Medicine, Atlanta, Georgia, November 1968 to October 1970 (Residency Training). 11. Associate Professor, Department of Anesthesiology (I was the first person to be appointed as Associate Professor in the history of Emory University after residency training); Yerkes Regional Primate Research Center, and Associate Professor of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia, November 1970 to 1972. 12. Staff Anesthesiologist, Georgia Baptist Medical Center, Atlanta, Georgia, 1972- 1997 13. Staff Anesthesiologist, Columbus Medical Center, Columbus, Georgia, 1976 to 1987. 14. . 15. Medical Director, SouthEastern Pain Institute, (SEPI) Georgia Baptist Medical Center of Atlanta, 1990s to 1997 16. Clinical Professor: Department of Anesthesia, Medical College of Georgia, Augusta, GA 30912-2700 up to 1997, Associate professor Emory University School of Medicine, Medical Staff: Columbus Medical Center, Columbus, GA 17. Medical Director, Yerkes Regional Primate Center of Emory University, Atlanta, GA. 18. Associate Chairman and staff Member, Department of Anesthesia, Georgia Baptist Medical Center (now Atlanta Medical Center) 353 Parkway, Atlanta, GA 30312

19. Staff Member: Millennium Health Care,4370 George town Sq. Atlanta, GA 30338, Avatar Cancer Center, 1867 Independent Sq, Atlanta, GA, 30338 Alternative Survival Medicine, Inc, Fountain of Youth Health Care Center, PC

Bio Data (CV) of Dr. T. R. Shantha 9 Sunday, October 12, 2008 Page 9 of 37 20. Visiting Professor, J. J. M. Medical College, Davanagere, Karnataka, India, 1989-present

Distinctions:

1. Awarded gold medal and numerous other prizes in final matriculation examination (1951). Awarded Kapoorchand Gold Medal by Maharaja of Mysore, Jaya Chama Rajendra Wadiar at Chitaldrug high school grounds. 2. Distinction (center rank) in Surgery and Pathology in final M.D. examination (1958). 3. Made numerous "A" grades in various courses taken as Ph.D. student (1960-62). Obtained Ph.D. within the minimum prescribed time (6 quarters i.e. 18 months) by Emory University. 4. Awarded two prizes from the Georgia Society of Anesthesiologists in 1969 and 1970 in an Anesthesia Residency essay competition on subjects concerned with Anesthesiology. (1. Pain: A Dilemma, 1969; 2. Reflexes in Anesthesia, 1970). 5. Listed in Who's Who in American Men of Science and in Outstanding Atlantan’s (Heritage publication, 1978-79) 6. Received A.M.A. Physician Recognition Award during 1970-1996. The latest one was for 3 years starting from 1997. 7. Declared Dr. Shantha day by DeKalb county Chief executive (CEO- Ms. Leona Levitan) and the county commissioners in honor of my contribution in research, humanitarian and philanthropic work in 1993. 8. Proclaimed honorary citizen by City of Atlanta, New Orleans, Knoxville, Topeka Kansas, Kansas city of Missouri, and Kentucky cornel etc. 9. He was selected as the distinguished physician and Scientist by American Association of Physicians from India (AAPI) for the year 2005. This association has 42000 physicians practicing in US. In the same year he was also awarded the distinguished service award by VSNA society of India at Maryland convention.

PATENTS ISSUED; PATENTS AND TRADEMARKS REGISTERED:

1. Patent # 5,195,965 March 23, 1993. Method and apparatus for localized treatment of human viral infections. It can be used in many diseases including HPV infection, esophageal cancers, chronic interstitial cystitis, Uterine bleeding in post menopausal woman etc.

2. Patent: Trans-sphenoid stimulation for treatment of Alzheimer's, Parkinsonism, pain, senile brain atrophy, addiction, mental diseases of various kinds etc. The patent number 5735817, April 7, 1998

3. Patent # 5,792,100 August 11, 1998. The treatment method for Trans sphenoidal Stimulation of the pituitary Gland and the of nerve structures. Equal owner of patent on e-Lamp:

4. Part owner of United States Patent 6,285,119; September 4th 2001 with Shaam. Light bulbs having increased efficiency without using mercury.

Bio Data (CV) of Dr. T. R. Shantha 10 Sunday, October 12, 2008 Page 10 of 37 This invention is under UL and Energy efficiency testing. Can be in the market by 2008.

5. Part owner of United States Patent on e-Lamp with Shaam: Light Bulb Device. Design patent. US D461, 260 S, August 6th 2002. This can be used in the above patent and many other inventions such as CFL and LED light bulbs. It is environmentally friendly.

SUBMITTED ON THURSDAY, AUGUST 16, 2007

The Provisional Patents: By Shantha and Shaam

6. 2007: IN THE UNITED STATES PATENT AND TRADEMARK OFFICE the following provisional patent applications were filed by Dr. Shantha and Dr. Shaam Sundhar as applicants. These applications can be converted to real patents within a year.

i. Title: e-LAMP II: Date Mailed: Thursday, August 16, 2007; Provisional Patent Application; Commissioner of Patents and Trademarks; P.O. Box: 1450; Alexandria, VA 22313-1450. This design patent application is environment friendly and will only dispose only mercury bulb keeping the register to be used for the next bulb insert.

ii. Title: SELF ILLUMINATING NUMERS ON POST BOX, DOOR, STREET NUMBERS AND NAMES, STREET NAMES ON THE POSTS, NAME PLATE WITH STREET NUMBERS ON THE LAWNS, ADVERTISEMENT ON MOTOR VEHICLES WITH MAGNETIC SHEET WITH TELEPHONE NUMBERS AND NAME OF THE PERSON OR COMPANY AND THE SERVICE OR PRODUCT THEY SELL. Provisional Patent Application; Commissioner of Patents and Trademarks; P.O. Box: 1450; Alexandria, VA 22313-1450. Date mailed: Saturday, August 18 th , 2007

iii. Title: SELF ILLUMINATING ELECTRICAL PLATES, SWITCHES, EXTENSION CARDS, LAMP POSTS, DOOR KNOBS, TV CHANGERS, TELEPHONES, CELL PHONES, TOYS, KITCHEN GADGETS, CYCLE HELMETS AND LUMINICENT RAIDERS MARKERS. Provisional Patent Application; Commissioner of Patents and Trademarks; P.O. Box: 1450; Alexandria, VA 22313-1450. Date mailed: Saturday, August 18 th , 2007

iv. Title: Method and Apparatus for the Prevention of Sudden Infant Death Syndrome (SIDS). Provisional Patent Application; Commissioner of Patents and Trademarks; P.O. Box: 1450; Alexandria, VA 22313-1450. Date mailed: Saturday, August 18 th , 2007.

SUBMITTED ON NOVEMBER 19 TH , 2007

Bio Data (CV) of Dr. T. R. Shantha 11 Sunday, October 12, 2008 Page 11 of 37 v. Title: Dual filament Electric Bulb. Provisional Patent Application; Commissioner of Patents and Trademarks; P.O. Box: 1450; Alexandria, VA 22313-1450. Date mailed: Monday, November 19 th , 2007.

Since the introduction of Modern electric bulb by Thomas Edison bulb in 1879, there is no change in the incandescent (glowing, luminescent) bulb basics. This is the first time changes are made in this classic Edisonian incandescent bulb. We have come with this simple concept after 128 years of its introduction to extend the life by double, and at the same time environmentally friendly by conserving the bulb which are easily thrown out when it burns out. Our bulb has two filaments; when one filament burns out; the other filament is turned on by a simple method instead of throwing it out as useless. Our bulb conserves 80 of the energy and material used to produce the Edison bulb every time we throw a burnt out bulb. We can also double the amount of lumens of lighting (brightness) given by lighting both the filaments.

vi. Title: Flat CFL* with separable ballast. Provisional Patent Application; Commissioner of Patents and Trademarks; P.O. Box: 1450; Alexandria, VA 22313-1450. Date mailed: Monday, November 19 th , 2007.

vii. Title: Sun Sensor Automatic Electric Bulb turning on at Dusk, and turning off at Dawn. Provisional Patent Application; Commissioner of Patents and Trademarks; P.O. Box: 1450; Alexandria, VA 22313-1450. Date mailed: Monday, November 19 th 2007

Submitted in July 2008: These Provisional patents are in Dr.Shantha’s and his daughter’s name. (Jessica, Erica, and Lauren as second, third and fourth inventors). Patent applications will be submitted in November 20008

viii. Transmucosal delivery of insulin and therapeutic agents Provisional Patent Application; Commissioner of Patents and Trademarks; P.O. Box: 1450; Alexandria, VA 22313-1450. Date mailed: June 5 th 2008

ix. Transdermal local anesthetic patch with injection port Provisional Patent Application; Commissioner of Patents and Trademarks; P.O. Box: 1450; Alexandria, VA 22313-1450. Date mailed: June 16 th 2008

PATENTS UNDER PREPARATION:

1. Special Delivery system device for delivering therapeutic agents to olfactory region to treat Alzheimer’s, Parkinson’s, autism, depression, rabies, and many neurological diseases. 2. Use of Hyperbaric therapy combined with Insulin to deliver the drugs to brain, spinal cord, epidural space, spinal and cranial canal, eyes, ears and pituitary gland

Bio Data (CV) of Dr. T. R. Shantha 12 Sunday, October 12, 2008 Page 12 of 37 to treat nervous system diseases of all kind using anti tumor necrosis factors and other diagnostic, therapeutic pharmacological, biologic and nutriceuticals preparations. 3. Breast cooler to prevent cancer development 4. Stem Cell and Immune antibodies production enhancement by Vibrating, Vibroacoustic methods used on the thymus, cranial, vertebral, ribs, and pelvic bones. 5. Steam system for barbecue grills, grill wonder skewers, Bread toast messenger 6. Air conditioned Helmet, Hair saving hat to be worn during chemotherapy to prevent hair loss. 7. All climate (heated and / or cooled) shoes; Mobile ice cube maker; Energy saving light bulb technology; self illuminating plastic products for house number, names, electrical plates, Night shining glass etc 8. Testicular cooler to improve the sperm out put and male conception 9. Chelation and Antioxidant therapy for Cataract and glaucoma. 10. Antioxidant, cinnamon and green tea bag and Curcumin (turmeric) for brewing daily drinks to treat cancers, diabetes, neurological diseases etc. 11. Treatment of Rabies with Ketamine, Sulfasalazine, Progesterone, Insulin Potentiation therapy, low dose oral vaccine during the disease with vitamin B complex infusion, Intranasal Anti TNF such as Etanarcept etc. 12. Autism treatment with Anti TNF, antioxidants, and Insulin combined with hyperbaric therapy and / or vibroacoustic and vibrating methods. 13. Hyperbaric therapy combined with beta blockers, progesterone, Ambien, anti Parkinson drugs, intra nasal anticytokins, Chelation therapy antioxidants, and essential fatty acids to treat GWS, brain injuries, strokes, mental diseases, other nervous system afflictions of Iraq and Vietnam war and post surgical mental affliction lasting more than 2 hours 14. Air conditioning using Propane gas in cylinders and non toxic coolant as coolant fluid. This will be useful in India, China, Africa, Middle East, South America and other under developed countries where the electricity supply is unreliable. This being developed in collaboration with Engineer 15. Operating room blood and fluid warmer and cooler and Strontium labeling system for anesthesia and other equipments. 16. Peritoneal Hyperthermia treatment with chemotherapeutic agents, AIDS, Hepatitis B,C,D, Cancers. There are three patents in this method. 17. High dose and low dose anticancer therapy using traditional and alternative methods using insulin as a biological modifier called as IPT short for Insulin Primed Potentiation therapy. Two cycle Insulin Potentiation therapy (IPT) for treatment of cancers and other chronic incurable diseases. 18. Auto Immune therapy using Heat shock protein, fluids and tissue from the tumors, and using urine as source for antigen and antibodies. 19. Many patents on production of energy under bridges and median, electronics, lock systems, kitchen utensils, Vehicle covers, safety air bags, grills with humidity , transdermal drug delivery systems etc. 20. Peritoneal Hyperthermia treatment with chemotherapeutic agents, AIDS, Hepatitis B,C,D, Cancers. There are three-five patents in this method. 21. High dose and low dose anticancer therapy using traditional and alternative methods using insulin as a biological modifier called as IPT short for Insulin Primed Potentiation therapy. Two cycle Insulin Potentiation therapy (IPT) for treatment of cancers and other chronic incurable diseases 22. Many patents on production of energy under bridges and median, electronics, lock systems, kitchen utensils, Vehicle covers, safety air bags, grills with humidity , trans-dermal –mucosal drug delivery systems etc.

Bio Data (CV) of Dr. T. R. Shantha 13 Sunday, October 12, 2008 Page 13 of 37 23. All climate (heated and / or cooled) shoes. 24. Treatment of Rabies which is 100% fatal. 25. Operating room blood warmer 26. Three patents under preparation to develop a crib and bed lining to prevent SUDDEN INFANT DEATH SYNDROME (SIDS). This will save hundreds of infant lives. 27. Treatment of Autism, Parkinson’s, Alzheimer, pain, and Rabies 28. Treatment of Alopecia and enhance Eye lid hair growth..

Publications:

Author of more than 125 research papers and review articles and 7 books (listed below). I am the only scientist, physician cum anesthesiologist to publish 7 articles in the distinguished British Research Journal Nature, Science, New England Journal of Medicine, National Cancer Institute, Journal, Journal of Cell Biology, and many other research journals all over the world.

Scientific Society Affiliations previous and now:

Previous and Current: Member of the Sigma Xi Society Member of the Southern Society of Anatomists of the U.S.A. Member of the International and American Histochemical Society Member of the American Association of Anatomist

Fellow of the Zoological Society of London (F.Z.S.),Fellow of the Royal Microscopical Society of England (F.R.M.S.) Member of the American Society of Anesthesiologists, Member of the Medical Association of Georgia and Atlanta Member of the American Medical Association Member of the Georgia Society of Anesthesiologists and Southern Society of Anesthesiologists Member of the Greater Atlanta Society of Anesthesiologists Member of the Indian Medical Council Member of the American Academy of Pain Management Patron member and member: American Association of Physicians from India (AAPI AND GAPI,) American Association of Regional Anesthesia, Member of ACAM and A4M Life member and past-trustee of Atlanta chapter, Veerashaiva Samaj of North America Member: Under sea and Hyperbaric Medical Society. E.C.F.M.G. Certification: Passed the examination given by the Education Council for Foreign Medical Graduates Board (E.C.F.M.G. Certificate No.63869, 1965), American Society of Clinical Oncology, (ASCO) 2003-presetn

Bio Data (CV) of Dr. T. R. Shantha 14 Sunday, October 12, 2008 Page 14 of 37 Board Certifications:

1. Fellow of the American College of Anesthesiologists, 1973, No. 5780 (F.A.C.A) 2. Diplomat of the American Board of Anesthesiology, 1973, No. 6106 (D.A.B.A.) 3. Diplomat of the American Academy of Pain Management, 1992, No. 41208 (D.A.P.M) 4. Diplomat, Clinical Electro medical Research Academy, 1996, No. 7270 5. Diplomat of the American Board of Pain management, 1996,No. 06106 6. Certified and Trained in Hyperbaric Medicine May 21, 1999 by the Hyperbaric Medicine Program of Palmetto Richland Memorial hospital.

Medical License:

License to Practice Medicine and Prescribe Controlled Substances: Licensed in state of Georgia in the year 1972 to practice medicine and surgery (No. 014721); India, in 1955- 1958 (No. 1971).

Controlled Substance registration certificate, Schedule 2, 2N, 3, 3N, 4, 5, No. AS- 3057456

Charitable Educational Institution Built:

1. Provided major finances to build girls high school in Hosadurga, India, in my beloved father and mother's name. It provides excellent facilities for 300 girls to study. Plan to expand the school to accommodate more students when funds are available. Address: Totada Ramaiah Gowramma Memorial Girl's High School, Hosadurga, Chitradurga District, Karnataka State, India. 2. Provided major funds to rebuild Sangameswara Temple in Janthikolalu, Hosadurga Taluk, Chitaldrug District, Karnataka Sate, India 3. Supported the education of many needy children in India who could not afford and improved their quality of life. 4. Provided more than $35,000.00 worth of laboratory equipment to the Morehouse Medical College, Atlanta. 5. Invested more than $910,000.00 to build Ophthalmic institute in India to serve the poor, a 1000 acre boy and girl scout camp in southeast of US, and scholarship fund at MLK center. The traders are to fund this project up to 15 millions dollars. Unfortunately, I lost the money and projects due to cheating of the traders. I have not lost the hope to do these charitable projects yet. 6. Dr. T. R. Shantha worked every week providing free medical care for the indigenous needy in a charitable clinic in McDonough called “Hands of Hope” organized by Saint James Church up to 2006.

Research Projects under Study and Development:

1. Developing a project to treat Human Papilloma Virus infection, which afflicts 30 million people in U.S.A. and untold millions all over the world? To start projects to treat AIDS, Interstitial cystitis, ovarian cancer, PID, Endometriosis, Antibiotic

Bio Data (CV) of Dr. T. R. Shantha 15 Sunday, October 12, 2008 Page 15 of 37 resistant infections, pancreatic cancer, Colon cancer, prostate cancer with secondary deposits in the pelvic lymph node, septic shock ETC with peritoneal hyperthermia combined with chemotherapeutic agents. This method may cure, and/or prolong the life, and make them pain free. Case report in one case with intractable peritoneal infection by Candida showed us this method does work. 2. Setting up a project at Karnataka state leprosarium and tuberculosis institutes at Davanagere to study the effects of hyperthermia combined with antimicrobial agents and insulin potentiation therapy and hyperbaric therapy. 3. Rabies is incurable. Seeking centers to study the effects of continuous hyperthermia combined with autoimmune therapy, Ketamine, Sulfasalazine, DMSO, and B Vitamin infusion, sedative, Inducing continues hypoglycemia up to 40-50 mg% etc.. It is believed that we can save at least 50% of these patients. 4. Setting up a ophthalmic research center with 300 bed hospital 5. Subdural intra-arachnoid injection of steroids for acute and chronic post herpetic neuralgic pain, chronic backache, and implantation of electrodes in this space is being studied. 6. Planning a project to study the effects of growth hormones and anabolic steroids in debilitated bedridden intensive care patients, diabetics and post operative patients, type ll diabetics, and anabolic steroid use in advanced stage four cancers except in prostate cancers. 7. Studying the method of relieving pain by using continuous epidural after lumbar laminectomy and other back surgery and for back pain patients with inversion bar stretching with epidural steroid injections. This alleviates suffering in hundreds of patients who undergo back surgery. These patients can go home early and resume function. 8. Study the effect of botulism toxins and magnesium sulfate in relieving the chronic myofascial pains. 9. Intravenous regional anesthesia using hypoglycemia method to relive pain and RSD. 10. Treatment of psoriasis, eczema and many other skin diseases of the extremities by using multiple hyperthermias with low dose therapeutic agents and Insulin potentiation therapy (IPT) along with autoimmune therapy are being explored. 11. Treatment of Interstitial cystitis using hyperthermia is being explored. At present there is no curative therapy. 12. Treatment of resistant Tuberculosis of the lungs and other infections of the lungs, and other regions using hyperthermia, Hyperbaric therapy, IPT, antibiotic and chemotherapeutic agents. 13. Development of devices to stimulate the hypothalamus and other parts of the nervous system through nerve tracks to relieve chronic pain, Alzheimer disease, addictions, mental problems and various other central nervous system diseases. The patent is applied for the device and received and more patents are going to be applied. 14. Setting up cancer clinics using Insulin Potentiation Therapy, low and high dose anticancer agents, Hyperthermia, Hyperbaric method etc. Establish also cancer prophylaxis clinics and centers to treat various neurological (Alzheimer’s, autism, stroke, senile dementia and other diseases using hyperbaric therapy.

Bio Data (CV) of Dr. T. R. Shantha 16 Sunday, October 12, 2008 Page 16 of 37 RESEARCH PUBLICATIONS

1962 Shantha TR and Bourne GH: A Perineural epithelium. J Cell Biology, Rockefeller University NY, 14(2):343-346 (1962). Shantha TR and Bourne GH: Histochemical studies of the distribution of dephosphorylating and oxidative enzymes and lipids in the facial and trigeminal nerves of rat. Acta Anat 51:112-124 (1962). Shantha TR and Bourne GH: The `Perineural epithelium', a metabolically active, continuous, protoplasmic cell barrier surrounding peripheral nerve fasciculi. J Anat Lond 96(4):27-37 (1962). Shantha TR and Bourne GH: Radial bands in the optic nerve myelin sheath. J Nature 4860:1215-1217 (1962).

1963 Shantha TR and Bourne GH: Further histochemical observations of the radial bands of the optic nerve myelin sheath. Experimental Cell Research 32:196-199 (1963). Shantha TR and Bourne GH: Some observations on the corneal endothelium. Acta Ophthalmologica 41: 683-688 (1963). Shantha TR and Bourne GH: Demonstration of Perineural epithelium in vagus nerves. Acta Anat 52:95-100 (1963). Shantha TR and Bourne GH: New observations on the structure of the Pacinian corpuscle and its relation to the Perineural epithelium of peripheral nerves. Amer J of Anat 112(1):97- 109 (1963). Shantha TR, Nandy K, and Bourne GH: Histochemical studies on the mechanism of action of the hallucinogens d-lysergic acid diethylamide tartrate (LSD-25) and d-2- Bromo-lysergic acid tartrate (BOL-148) in rat brain. Acta Neuropath 3:29-39 (1963). Shantha TR and Bourne GH: An autonomic ganglion neurons in a small branch of the right sciatic nerve of the rat. J Nature 198, 4868:607-608 (1963). Shantha TR and Bourne GH: The Perineural epithelium: and significance. J Nature 199, 4893:577-579 (1963). Shantha TR and Bourne GH: Demonstration of Perineural epithelium in whale and shark peripheral nerves. J Nature 197, 4868:702-703 (1963). Shantha TR, Hope J, and Bourne JH: Electron microscopic demonstration of the perineural epithelium in rat peripheral nerve. Acta Anat 52, 3:193-201 (1963).

1964 Shantha TR and Bourne GH: Histochemical studies on the distribution of acid phosphatase in the eye. Acta Histochem Bd 18:317-327 (1964). Shantha TR and Bourne GH: Observations on the histological structure of the sclera of the eye. Acta Anat 58:396-305 (1964). Shantha TR and Bourne GH: Arachnoid villi in the optic nerve of man and monkey. Expt Eye Res 3:31-35 (1964). Shantha TR and Bourne GH: Monoamine oxidase distribution in the rabbit eye. J Histochemistry and Cytochemistry 12(4):281-287 (1964). Nandy K, Shantha TR and Bourne GH: The effect of d-lysergic acid diethylamide tartrate (LSD-25) and d-2-bromo lysergic acid tartrate (BOL-148) on specific

Bio Data (CV) of Dr. T. R. Shantha 17 Sunday, October 12, 2008 Page 17 of 37 cholinesterase and monoamine oxidase of rat liver as possible factors in the mechanism of hallucination. A histochemical study. Acta Histochemica Bd 17:259-267 (1964). Shantha TR and Bourne GH: The Perineural epithelium of sympathetic nerves and ganglia and its relation to the pia-arachnoid of the central nervous system and Perineural epithelium of the peripheral nervous system. Zeitschritc fur Zellforschung 61:742-753 (1641). Shantha TR and Bourne GH: Histochemical studies on the distribution of B- glucuronidase in the eye. Histochemie 3:413-421 (1964). Shantha TR and Bourne GH: The effects of transection on the nerve trunk on the Perineural epithelium with special reference to its role in nerve degeneration and regeneration. Anatomical Record (US) 150(1):35-50 (1964). Shantha TR and Bourne GH: Histochemical studies on the distribution of oxidative and dephosphorylating enzymes of the rabbit eye. Acta Anat 57:193-219 (1964). Shantha TR and Bourne GH: Deficiency in the Descemet's membrane of the cornea. J Nature 202, 4939:1347-1348 (1964).

1965

Baer GM, Shantha (Shanthaveerappa in pervious publications) T.R, Bourne G.H. Studies on the Pathogenesis of Fixed Rabies Virus in Rats. Bull. World Hlth Org, 33: 783-794(1965).

Shantha TR and Bourne GH: Histochemical studies on distribution of dephosphorylating and oxidative enzymes and esterases in olfactory bulb the squirrel monkey. J National Cancer Inst 35(1):153-165 (1965). Shantha TR, Manocha SL, and Bourne GH: Macro photography of thick sections and gels with a regular photographic enlarger. Stain Tech 40(5):309 (1965). Shantha TR and Bourne GH: Histochemical studies on the olfactory glomeruli of squirrel monkey. Histochemie 5:125-129 (1965). Shantha TR and Bourne GH: Histochemical demonstration of thiamine pyrophosphatase and acid phosphatase in the Golgi region of the cells of the eye. J Anat Lond 99(1):103- 117. Shantha TR and Bourne GH: A simple method for preparation and staining of the whole Pacinian corpuscle. Acta Anat 60:199-206 (1965). Shantha TR and Bourne GH: Histochemical studies on the distribution of oxidative and dephosphorylating groups of enzymes. Amer J of Ophthalmology 60(1):49-55 (1965). Shantha TR and Bourne GH: The thiamine pyrophosphatase technique as an indicator of the morphology of the Golgi apparatus in the neurons. II. Studies on the cerebral cortex. La Cellule 65(2):201-209 (1965). Shantha TR and Bourne GH: The thiamine pyrophosphatase technique as an indicator of the morphology of the Golgi apparatus in the neurons. Acta Histochemica 22:155-178 (1965). Baer GM, Shantha TR and Bourne GH: Studies on the pathogenesis of fixed rabies virus in rats. J Bulletin of the World Heath Organization 33:783-794 (1965). Shantha TR and Bourne GH: Histochemical studies on the localization of oxidative and dephosphorylating enzymes and esterases in the peritoneal mesothelial cells. Histochemie

Bio Data (CV) of Dr. T. R. Shantha 18 Sunday, October 12, 2008 Page 18 of 37 5: 331-338 (1965). Shantha TR and Bourne GH: Histological and histochemical studies of the choroid of the eye and its relations to the pia-arachnoid mater of the central nervous system and Perineural epithelium of the peripheral nervous system. Acta Anat 61:379-398 (1965). Shantha TR and Bourne GH: The thiamine pyrophosphatase technique as an indicator of the morphology of the Golgi apparatus in the neurons. III. Studies on the olfactory bulb. Expt Cell Res 40:292-300 (1965). Shantha TR and Bourne GH: The thiamine pyrophosphatase technique as indicator of the morphology of the Golgi apparatus in the neurons. Zeitschrift fur Zellforschung 68:699-710 (1965).

1966 Shantha TR and Bourne GH: Double central canal in spinal cord of rat. British Journal Nature; 209:729 (1966). Shantha TR and Bourne GH: Histochemical studies on the Pacinian corpuscle. Am J Anat 118: 461-470 (1966). Shantha TR, Woods WD, Waitzman MB and Bourne GH: Histochemical method for localization of cyclic 3',5'-nucleotide phosphodiesterase. Histochemie 7:177-190 (1966). Waitzman MB, Jackson RT, Kuck Jr JFR, Shantha TR and Woods WD: Influences of metabolic-effective agents on nucleotide systems in ocular tissues. Am J Physiol 210:1249-1256 (1966). Shantha TR and Bourne GH: Perineural epithelium: A new concept of its role in the integrity of the peripheral nervous system. Science 154:1464-1467 (1966). Shantha TR and Bourne GH: The thiamine pyrophosphatase technique as an indicator of morphology of the Golgi apparatus in the neurons. VI. Studies on the spinal cord, hippocampus, and trigeminal ganglion. Ann Histochemie 11:337-351 (1966). Shantha TR and Bourne GH: The thiamine pyrophosphatase technique as an indicator of morphology of the Golgi apparatus in the neurons. V. Studies on sympathetic ganglion cells. Cytologia 31:132-143 (1966). Shantha TR, Waitzman MB and Bourne GH: Studies on the distribution of phosphorylase in eyes of the rabbit and the squirrel monkey. Histochemie 7:80-95 (1966). Shantha TR and Bourne GH: Pacinian corpuscles on the olfactory bulb of the squirrel monkey. J Nature, 209:1260 (1966).

1967

Shantha TR and Bourne GH: Nature and origin of perisynaptic cells of the motor end plate. Int Rev Cytol 21:353-364, 1967 (GH Bourne and JF Danielli, edited.) Academic Press, New York. Iijima K, Shantha TR and Bourne GH: Enzyme-histochemical studies on the hypothalamus with special reference to the supraoptic and paraventricular nuclei of Squirrel Monkey (Saimiri sciureus). Z Zellforsch 79:76-91 (1967). Manocha SL, Shantha TR and Bourne GH: Histochemical studies on the spinal cord of Squirrel Monkey (Saimiri scieureus). Expt Brain Res 3:25-39 (1967). Iijima K, Bourne GH and Shantha TR: Histochemical studies on the distribution of enzymes of glycolytic pathways in the area postrema of the Squirrel Monkey. Acta Histochem 27:42-54 (1967).

Bio Data (CV) of Dr. T. R. Shantha 19 Sunday, October 12, 2008 Page 19 of 37 Shantha TR, Iijima K and Bourne GH: Histochemical studies on the cerebellum of Squirrel Monkey (Saimiri sciureus). Acta Histochem 27:129-162 (1967). Iijima K, Shantha TR and Bourne GH: Histochemical studies on the distribution of some enzymes of the glycolytic pathways in the olfactory bulb of the squirrel monkey (Saimiri sciureus). Histochemie 10:224-229 (1967). Shantha TR, Manocha SL and Bourne GH: Histochemical mapping of the distribution of monoamine oxidase in the diencephalon and basal telencephalic centers of the brain of the squirrel monkey (Saimiri sciureus). Brain Res 6:570-586 (1967). Manocha SL, Shantha TR and Bourne GH: Histochemical mapping of the distribution of monoamine oxidase in the diencephalon and basal telencephalic centers of the brain of the squirrelmonkey(Saimiri scieureus).

Rajasekhar K and Shantha TR: Relationship of coconut consumption and coronary disease. Southern Medical Journal 70:766, 1977.

1968 Baer G, Shantha TR and Bourne GH: The pathogenesis of street rabies virus in rats. Bull World Hlth Org, 38(1):119-125 (1968). Iijima K, Shantha TR and Bourne GH: Histochemical studies on the distribution of enzymes concerned with carbohydrate metabolism in rabbit and squirrel monkey tongue (with special reference to taste buds). Acta Anatomica 69:183-200 (1968). Iijima K, Shantha TR and Bourne GH: Histochemical studies on the nucleus basalis of Meynert of the squirrel monkey (Saimiri sciureus). Acta Histochem Bd 30:96-108 (1968). Nakajima Y, Shantha TR and Bourne GH: Histological and histochemical studies on the subfornical organ of the squirrel monkey. Histochemie 13:331-345 (1968). Shantha TR, Manocha SL: Enzyme histochemistry of the choroid plexus in rat and squirrel monkey. Histochemie 14:149-160 (1968). Shantha TR, Manocha SL, and Bourne GH: Enzyme histochemistry of the cerebral cortex of squirrel monkey and rat. Acta Histochem 30:218-233 (1968).

1969 Shantha TR and Bourne GH: The "Perineural Epithelium": A new concept. Its role in the integrity of the peripheral nervous system. In Structure and Function of Nervous Tissues. I. (GH Bourne, Ed.). Academic Press, New York. 1969. (For this work, he was nominated to receive Nobel Prize in Physiology and Medicine for the year 2007) Nakajima Y, Shantha TR and Bourne GH: Histochemical detection of L-gulonolactone: phenazone methosulfate oxidoreductase activity in several mammals with special reference to synthesis of vitamin C in primates. Histochemie 18:293-302 (1969). Iijima K, Shantha TR and Bourne GH: Histochemical studies on the pigments and distribution of various enzymes in the dorsal vagal nucleus and hypoglossal nucleus of the squirrel monkey. Acta Histochemie 32:18-36 (1969). Shantha TR and Manocha SL: The brain of chimpanzee (Pan troglodytes). I. External Morphology. In "The Chimpanzee" Vol. I (GH Bourne, ed.) pp 188-237. Karger, Basel, New York, 1969.

Bio Data (CV) of Dr. T. R. Shantha 20 Sunday, October 12, 2008 Page 20 of 37 Shantha TR and Manocha SL: The brain of chimpanzee (Pan troglodytes). II. Basal ganglia, septal area, epithalamus, dorsal thalamus, metathalamus, subthalamus, and hypothalamus. In "The Chimpanzee" Vol. I (GH Bourne, ed.) pp 238-305. Karger, Basel, New York, 1969. Shantha TR and Manocha SL: The brain of chimpanzee. III. Midbrain, pons, medulla oblongata and cerebellum. In "The Chimpanzee" Vol. I (GH Bourne, ed.) pp 306-368. Karger, Basel, New York, 1969.

1970

Shantha T.R. and Yasuo Nakajima of Yerkes Regional Primate Research Center, Emory University, Atlanta, Georgia: Histological and Histochemical Studies on the Rhesus Monkey (Macaca mulatta) Olfactory Mucosa. Z. Zellforsch. 103, 291—319 (1970)

Pain a Dilema: Emory University Anesthesia research contest. Won first prize

1971

Reflexes in Anesthesia: Emory University Anesthesia research contest. Won first prize

1972

Shantha TR and Evans JA: Arachnoid Villi in the Spinal Cord, and Their Relationship to Epidural Anesthesia. Anesthesiology 37:543-557, 1972.

1973 Shantha TR and McWhirter WR: Complications of Epidural Blood Patch for Spinal Headache. Anesthesia and Analgesia 52:67-69, 1973. Shantha TR: Ketamine for the treatment of hiccup during and following anesthesia. A preliminary report. Anesthesia and Analgesia 52:822-824, 1973. Dunbar R and Shantha TR: Cervical peridural block: Questions and Answers. Anesthesia and Analgesia 52:279-280, 1973.

REVIEW ARTICLES BY T. R. SHANTHA

Nandy K, Shantha TR and Bourne GH: Histochemical approaches to the study of the central nervous system. Meth Achievm Exp Path 1:52-95 (E Gajusz and G Jasmin, Eds.) S. Karger, Basel/New York, 1966. Shantha TR and Bourne GH: Nature and origin of perisynaptic cells of the motor end plate. Int Rev Cytol 21:353-364, 1967 (GH Bourne and JF Danielli, edited.) Academic Press, New York. Shantha TR and Bourne GH: The "Perineural Epithelium": A new concept. Its role in the integrity of the peripheral nervous system. In Structure and Function of Nervous Tissues. I. (GH Bourne, Ed.). Academic Press, New York. 1969. (For this work, he was nominated to receive Nobel Prize in Physiology and Medicine for the year 2007)

Bio Data (CV) of Dr. T. R. Shantha 21 Sunday, October 12, 2008 Page 21 of 37 Bourne GH, Manocha SL and Shantha TR: Enzyme histochemistry of the nervous system. In Structure and Function of Nervous Tissues. Vol. II (GH Bourne, Ed.). Academic Press, New York. 1970. Shantha TR and Manocha SL, Bourne GH and Kappers JA: Morphology and cytology of neurons. In Structure and Function of Nervous Tissues. Vol. II (GH Bourne, Ed.). Academic Press, New York. 1970

1972 OTHER RESEARCH ARTICLES AFTER 1970

Shantha TR: Intraoperative Management of Penile Erection by Using Terbutaline. Anesthesiology 70: 707-709 (1989). Shantha TR, Finnerty DP and Rodriguez AP: Treatment of Persistent Penile Erection and Priapism Using Terbutaline. J Urol 141:1427-1429 (1989). Shantha TR, Shantha DT, Bennett J: Sexual Emergencies: Priapism. Human Sexuality pp 63-67 (April 1990). Shantha TR: The Relationship of Retrobulbar Local Anesthetic Spread to the Neural Membranes of the Eyeball, Optic Nerve and Arachnoid Villi in the Optic Nerve. Anesthesiology 73(No 3A):A850 (1990). Shantha TR: Mechanism of Horner's Syndrome Resulting From Epidural, Caudal, Intercostal, Interpleural and SympatheticNerve Blocks. Anesthesiology 62(No. 3A): A192 (September 1990). Shantha TR and Harden J: Laparoscopic cholecystectomy: Anesthesia-related complications and guidelines. Surgical Laparoscopy & Endoscopy 1(3):173-178 (1991). Shantha TR: Causalgia induced by telephone-mediated lightning electrical injury and treated by interpleural block. Anesthesia and Analgesia 73:502-510 (1991). Shantha TR: A simple method to retrieve irretrievable epidural catheters. Anesthesia and Analgesia 73:502-510 (1991). Shantha TR: Subdural blood patch for spinal headache. The New England Journal of Medicine 325(17):1252-1253 (1991). Shantha TR: Subdural space: What is it? Does it exist? ESRA/ASRA Congress Brussels, Regional Anesthesia 17(3S):85 (1992). Shantha TR: Peri-vascular (Virchow - Robin) space in the peripheral nerves and its role in spread of local anesthetics, ASRA Congress at Tampa, Regional Anesthesia 17 (March-April, 1992). Shantha TR: A simple method to retrieve irretrievable epidural catheters, World Congress of Anesthesiologists held in Hague, June 1992. Shantha TR: Unilateral bronchospasm after inter-pleural analgesia and its mechanism, World Congress of Anesthesiology, held in June 1992. Shantha TR: Unilateral bronchospasm after inter-pleural analgesia and its mechanism, Anesthesia and Analgesia 74:291-293, 1992. Shantha TR: Retrograde intubation’s using the sub-cricoid region, British J of Anesthesia 68:109-112 (1992). Shantha TR: Spinal nerve root is one of the preferred routes for transfer of drugs to the nerve roots and spinal cord from the epidural space, Anesthesiology 77:216-218 (1992). Kambam J and Shantha TR: Inter-pleural Analgesia in the Management of Pain, Pain Digest 1992, Vol. II, 18-27.

Bio Data (CV) of Dr. T. R. Shantha 22 Sunday, October 12, 2008 Page 22 of 37 Shantha TR: Anatomic and Histologic Basis for Inter-pleural Analgesia, Pain Digest, 1992, Vol. II, 3-17. Shantha TR and Fraga E: Inter-pleural Analgesia to Relieve Pain Induced by Tetracycline Pleurodesis, Pain Digest, 1992, Vol. II, 28-29. Shantha, TR: Brachial Plexus Block: A New Method, presented at International Symposium on Regional Anaesthesia, April 1996, Auckland, New Zealand. Shantha, TR: Stellate Ganglion Block: A New Method, presented at International Symposium on Regional Anaesthesia, April 1996, Auckland, New Zealand. Shantha, TR: Cervical Plexus Block: A New Method, presented at International Symposium on Regional Anaesthesia, April 1996, Auckland, New Zealand. Shantha, TR: occipital Nerve Block: A New Method, Journal of American Society of regional anesthesia. April 1997. Presented in the national meeting in April 1997.Published in Regional Anesthesia, Vol.22,# 2S, page 109, 1997 Shantha, TR: Sleep left side down and keep the doctors away, Inspirator International, Vol 11/1997, Edition 4/5, page24-28.

Research Presentation in the year 2004

Townsend letter: BEST OF NATUROPATHY IN 2004 – SLEEP LEFT SIDE DOWN

Best Publishing: OXYGEN THERAPIES: HYPERBARIC OCYGEN THERAPY (HBOT) AND HYPERBARIC AIR THERAPY WITH OCYGEN SUPPLEMENTATION (HBAT) TO TREAT CANCERS AND MANY OTHER ACUTE, CHRONIC, CURABLE AND INCURABLE DISEASES

Ft. Lauderdale, FL: HYPERBARIC OXYGENATION IN CP AND THE BRAIN- INJURED CHILD July 28-31, 2004

ICIM: INTERACTIONS AND ACTIONS OF NUTRITIONAL SUBSTANCES ON CANCERS, CHEMO THERAPY AND RADIATION. October 9, 2004

Ft. Lauderdale, FL: OXYGEN THERAPIES: HYPERBARIC OXYGEN (HBO-HBA), HYDROGEN PEROXIDE (H2O2) AND OZONE (O3) THERAPIES TO TREAT CANCERS AND OTHER DISEASES.

Las Vegas: HYPERBARIC OXYGEN THERAPIES FOR ALL AGES

Bio Data (CV) of Dr. T. R. Shantha 23 Sunday, October 12, 2008 Page 23 of 37 HYPERBARIC OXYGEN THERAPIES (HBO) FOR CANCERS AND OTHER INCURABLE DISEASES INCLUDING AGING

Cancun: 1. DISCOVERY OF INSULIN AND IPT AMAZING HISTORY 2. HIGH DOSE METHOTREXATE THERAPY USING IPT 3. LOCAL INJECTIONS OF TUMORS 4. TWO AND THREE CYCLE INSULIN POTENTIATION THERAPY June 28-July1, 2004 Presented at 2nd International congress on Insulin Potentiation therapy at Cancun.

Research Presentation in the year 2005 -2006 Hyperbaric and Antiaging medical conferences about prolonging life and reduce ravages of aging and advanced cancers. In Las Vegas ACAM and anti Aging Seminar.

ARTICLES RELATED TO PUBLIC EDUCATION

Shantha TR: How to prevent cancer. Tamil Nadu monthly magazine, a series of six articles (1988). Shantha TR: Political vendetta and don't nip us in the bud. Indian Express (April 20, 1989). Shantha TR: Women have same brain as men. News India, July 28, 1989. Shantha TR: Satish Chandra, scientist, and Harvard. News India (September 21, 1990). Shantha TR: Basavanna and Bible--about self-appointed, self-righteous people, Annual Issue of VSNA, Canadian edition (1992). Shantha TR: Let God, Let Go, VSNA Souvenir, 1994, Atlanta conference, 17th Annual Convention, page, 47 Shantha TR: sleep on the left side and keep the doctor away, VSNA Souvenir of the 18th Annual convention held at Baltimore, Maryland chapter, 1995 Shantha, TR: Sleep left side down and keep the doctors away, Inspirator International, Vol 11/1997, Edition 4/5, pages 24-28. Shantha, TR: Basavanna on Sinners and Their Salvation; VSNA Souvenir of the 21st Annual convention held at Washington DC hosted by Washington DC and Virginia chapters, 1999 Shantha T.R Jessica, Erica, Lauren T. Shantha, Usha Shantha Martin: Tribute to Mothers, Published in 3 magazines Khabar, Stone Mountain Signal, and Inspirator of Asia magazines. May 1999. Shantha, T.R. Sarvagna, Confucius of India. VSNA publication 1997?

ARTICLES UNDER PREPARATION

Bio Data (CV) of Dr. T. R. Shantha 24 Sunday, October 12, 2008 Page 24 of 37 hyperthermia congress in Destin Florida in the year 2000 +- Shantha TR: Subdural Intra-arachnoid Space: Its Use in Spinal Headache, Regional Anesthesia, and Pain. Shantha TR: Mechanism of Horner's Syndrome Resulting from Epidural, Caudal, Inter- costal, Inter-pleural and Sympathetic Nerve Blocks. Shantha TR et al: Use of Terbutaline to reduce bulging membranes during cerclage and facilitate Ureter - urethral stone passage with least pain.

Shantha TR: Anatomical and histological routes of spread of Rabies Virus.

BOOKS BY T.R. SHANTHA

First 5 books were published when Dr. Shantha was a faculty member in the Emory University School of Medicine, and Yerkes Regional Primate Center of Atlanta.

BOOKS UNDER RESEARCH AND PREPARATION

1. MLK: American Gandhi 2. On Jesus: a) Last 20+ hours and 43 days of Jesus Life. b) Worlds Greatest Positive Thinker. C) Sin in the House of God. 3. Judas Iscariot – First Christian, and first Christian Martyr (He was not a traitor or betrayer of Jesus as claimed. Without his action, there would be no Christianity as we know now. May produce a movie on Judas 4. Sleep on left side and live longer 5. Hyperthermia and The Water with Life: Treatise on auto urine therapy to cure incurable diseases such as cancers, skin diseases, AIDS, leukemia, lupus, asthma, obesity, etc. 6. Breast Cancer, What Women Should Know, 2nd Ed. 7. Cancer Busters 8. Insulin Potentiation Therapy (IPT) and its application for various acute curable and chronic incurable diseases including cancers.

Bio Data (CV) of Dr. T. R. Shantha 25 Sunday, October 12, 2008 Page 25 of 37 Dr. T. R. Shantha’s Publications of the eyes (Ophthalmic) Anatomy, Histology, Histochemistry, Enzymes, and Physiology as related to health and diseases

1. Shantha TR and Bourne GH: Radial bands in the optic nerve myelin sheath. J Nature 4860:1215-1217 (1962). 2. Shantha TR and Bourne GH: Histochemical studies on the distribution of acid phosphatase in the eye. Acta Histochem Bd 18:317-327 (1964). 3. Shantha TR and Bourne GH: Observations on the histological structure of the sclera of the eye. Acta Anatomica 58:396-305 (1964). 4. Shantha TR and Bourne GH: Arachnoid villi in the optic nerve of man and monkey. Expt Eye Res 3:31-35 (1964). Before this discovery was made, no experts on the eye knew how the optic nerve CSF pressure is released during coughing, bearing, lifting weight, straining, asthma attacks etc. which could create temporary blindness during these conditions. 5. Shantha TR and Bourne GH: Histochemical studies on the distribution of B- glucuronidase in the eye. Histochemie 3:413-421 (1964). 6. Shantha TR and Bourne GH: The effects of transection on the nerve trunk on the Perineural epithelium with special reference to its role in nerve degeneration and regeneration. Anatomical Record (US) 150(1):35-50 (1964). 7. Shantha TR and Bourne GH: Histochemical studies on the distribution of oxidative and dephosphorylating enzymes of the rabbit eye. Acta Anat 57:193- 219 (1964). 8. Shantha TR and Bourne GH: Deficiency in the Descemet's membrane of the cornea (eye). J Nature 202, 4939:1347-1348 (1964). 9. Shantha TR and Bourne GH: Histochemical demonstration of thiamine pyrophosphatase and acid phosphatase in the Golgi region of the cells of the eye. J Anat Lond 99(1):103-117. 10. Shantha TR and Bourne GH: Histological and histochemical studies of the choroid of the eye and its relations to the pia-arachnoid mater of the central nervous system and Perineural epithelium of the peripheral nervous system. Acta Anat 61:379-398 (1965). 11. Shantha TR, Waitzman MB and Bourne GH: Studies on the distribution of phosphorylase in eyes of the rabbit and the squirrel monkey. Histochemie 7:80- 95 (1966). 12. Waitzman MB, Jackson RT, Kuck Jr JFR, Shantha TR and Woods WD: Influences of metabolic-effective agents on nucleotide systems in ocular tissues. Am J Physiol 210:1249-1256 (1966). 13. Shantha TR: The Relationship of Retro bulbar Local Anesthetic Spread to the Neural Membranes of the Eye ball, Optic Nerve and Arachnoid Villi in the Optic Nerve. Anesthesiology 73(No 3A):A850 (1990).

Bio Data (CV) of Dr. T. R. Shantha 26 Sunday, October 12, 2008 Page 26 of 37 Dr. Shantha’s publications in Anesthesiology since 1969

1969

Pain: A Dilemma: Emory University Anesthesia Resident research contest. Won first prize

1970

Reflexes in Anesthesia: Emory University Anesthesia Resident research contest. Won first prize

1. Shantha TR and Evans JA: Arachnoid Villi in the Spinal Cord, and Their Relationship to Epidural Anesthesia. Anesthesiology 37:543-557, 1972. 2. Shantha TR and McWhirter WR: Complications of Epidural Blood Patch for Spinal Headache. Anesthesia and Analgesia 52:67-69, 1973. 3. Shantha TR: Ketamine for the treatment of hiccup during and following anesthesia. A preliminary report. Anesthesia and Analgesia 52:822-824, 1973. 4. Dunbar R and Shantha TR: Cervical peridural block: Questions and Answers. Anesthesia and Analgesia 52:279-280, 1973. 5. Shantha TR: Intraoperative Management of Penile Erection by Using Terbutaline. Anesthesiology 70: 707-709 (1989). 6. Shantha TR, Finnerty DP and Rodriguez AP: Treatment of Persistent Penile Erection and Priapism Using Terbutaline. J Urol 141:1427-1429 (1989). 7. Shantha TR, Shantha DT, Bennett J: Sexual Emergencies: Priapism. Human Sexuality pp 63-67 (April 1990). 8. Shantha TR: The Relationship of Retrobulbar Local Anesthetic Spread to the Neural Membranes of the Eyeball, Optic Nerve and Arachnoid Villi in the Optic Nerve. Anesthesiology 73(No 3A):A850 (1990). 9. Shantha TR: Mechanism of Horner's Syndrome Resulting From Epidural, Caudal, Intercostal, Interpleural and Sympathetic Nerve Blocks. Anesthesiology 62(No. 3A): A192 (September 1990). 10. Shantha TR and Harden J: Laparoscopic cholecystectomy: Anesthesia-related complications and guidelines. Surgical Laparoscopy & Endoscopy 1(3):173-178 (1991). 11. Shantha TR: Causalgia induced by telephone-mediated lightning electrical injury and treated by interpleural block. Anesthesia and Analgesia 73:502-510 (1991). 12. Shantha TR: A simple method to retrieve irretrievable epidural catheters. Anesthesia and Analgesia 73:502-510 (1991). 13. Shantha TR: Subdural blood patch for spinal headache. The New England Journal of Medicine 325(17):1252-1253 (1991). 14. Shantha TR: Subdural space: What is it? Does it exist? ESRA/ASRA Congress Brussels, Regional Anesthesia 17(3S):85 (1992).

Bio Data (CV) of Dr. T. R. Shantha 27 Sunday, October 12, 2008 Page 27 of 37 15. Shantha TR: Peri-vascular (Virchow - Robin) space in the peripheral nerves and its role in spread of local anesthetics, ASRA Congress at Tampa, Regional Anesthesia 17 (March-April, 1992). 16. Shantha TR: A simple method to retrieve irretrievable epidural catheters, World Congress of Anesthesiologists held in Hague, June 1992. 17. Shantha TR: Unilateral bronchospasm after inter-pleural analgesia and its mechanism, World Congress of Anesthesiology, held in Hague, June 1992. 18. Shantha TR: Unilateral bronchospasm after inter-pleural analgesia and its mechanism, Anesthesia and Analgesia 74:291-293, 1992. 19. Shantha TR: Retrograde intubation’s using the sub-cricoid region, British J of Anesthesia 68:109-112 (1992). 20. Shantha TR: Spinal nerve root is one of the preferred routes for transfer of drugs to the nerve roots and spinal cord from the epidural space, Anesthesiology 77:216-218 (1992). 21. Kambam J and Shantha TR: Inter-pleural Analgesia in the Management of Pain, Pain Digest 1992, Vol. II, 18-27. 22. Shantha TR: Anatomic and Histologic Basis for Inter-pleural Analgesia, Pain Digest, 1992, Vol. II, 3-17. 23. Shantha TR and Fraga E: Inter-pleural Analgesia to Relieve Pain Induced by Tetracycline Pleurodesis, Pain Digest, 1992, Vol. II, 28-29. 24. Shantha, TR: Brachial Plexus Block: A New Method presented at International Symposium on Regional Anaesthesia, April 1996, Auckland, New Zealand. 25. Shantha, TR: Stellate Ganglion Block: A New Method: presented at International Symposium on Regional Anaesthesia, April 1996, Auckland, New Zealand. 26. Shantha, TR: Cervical Plexus Block: A New Method: presented at International Symposium on Regional Anaesthesia, April 1996, Auckland, New Zealand. 27. Shantha, TR: occipital Nerve Block: A New Method: Journal of American Society of regional anesthesia. April 1997. Presented in the national meeting in April 1997.Published in Regional Anesthesia, Vol.22,# 2S, page 109, 1997 28. Shantha, TR: Sleep left side down and keep the doctors away, Inspirator International, Vol 11/1997, Edition 4/5, page24-28.

CHARITABLE WORK BY DR. SHANTHA

7. Provided major finances to build girls high school in Hosadurga, India, in my beloved father and mother's name. It provides excellent facilities for 300 girls to study. Plan to expand the school to accommodate more students when funds are available. Address: Totada Ramaiah Gowramma Memorial Girl's High School, Hosadurga, Chitradurga District, Karnataka State, India. Approximately 2000 girls have graduated since its inception in 1988. 8. Dr. T. R. Shantha along with other anesthesia members (Medical Center Anesthesia Associates-MCAA) made large charitable contribution to build Hospital Tower Building addition to the Georgia Baptist Medical Center Early 1970s This is part of Massive Hospital Tower Extension expansion of Georgia Baptist Medical center, which is now Atlanta Medical Center, located in the heart of Atlanta

Bio Data (CV) of Dr. T. R. Shantha 28 Sunday, October 12, 2008 Page 28 of 37 9. Provided major funds to rebuild Sangameswara Temple in Janthikolalu, Hosadurga Taluk, Chitaldrug District, Karnataka Sate, India 10. Supported the education of many needy children in India who could not afford and improved their quality of life. 11. Provided more than $35,000.00 worth of laboratory equipment to the Morehouse Medical College, Atlanta. 12. Invested more than $910,000.00 +700,000.00 dollars to build Ophthalmic institute in India to serve the poor, a 200-1000 acre land donation for boy and girl scout camp in southeast of US, and scholarship fund at MLK center. The traders are to fund this project up to 15 millions dollars. Unfortunately, I lost the money and projects due to cheating of the traders. I have not lost the hope to do these charitable projects yet. 13. Dr. T. R. Shantha worked every week (Monday evening) providing free medical care for the indigenous needy in a charitable clinic in McDonough called “Hands of Hope” organized by Saint James Church in Henry County every Monday evening up to 2005 December. 14. Dr. T. R. Shantha worked free for between 1972 -1975 providing medical services to the indigenous patients and teaching residents at the Emory and Grady Memorial Hospital of Atlanta. 15. As Professor of Medical College of Georgia Dr. T. R. Shantha volunteered for 5 years without salary to teach medical students from Medical College of Georgia rotating through Georgia Baptist Medical Center. 16. Treated hundreds of patients free of charge who did not have insurance and who could not afford pay for the medical care. 17. Besides this your honor, two my sons are doctors, one daughter is a PA in Macon, one daughter is a medical student in Morehouse School of Medicine, my fifth child is senior premed student at UGA and the last one in UAB at Tuscaloosa perusing Hospitality industry. All my children have participated in Charity work of various kinds all their teen age and adult life and contributed to the wellbeing of the Society where they live in. This month (March 2008) for spring break, my daughter went to Haiti on medical mission from Morehouse School of Medicine. 18. Invested in India since 1986 along with other investors, which has provided meaningful jobs to literally thousands native people though Sugar factories we built, and 5 star hotel (La Meridian Hotel in Chennai) we erected.

RESEARCH PROJECTS UNDER STUDY AND DEVELOPMENT:

1. Treat MRSA using insulin potentiation therapy with appropriate Antibiotics, Methicillin-resistant Staphylococcus aureus (MRSA) (usually pronounced in short as "Mursa" or spelled out as MRSA), is a bacterium responsible for difficult-to-treat infections in humans. It may also be referred to as multiply- resistant Staphylococcus aureus or oxacillin-resistant Staphylococcus aureus (ORSA). MRSA was discovered in 1961 in the UK. It is now found worldwide often referred to in the press as a super bug. MRSA is. It has evolved an ability to survive treatment with beta-lactam antibiotics, including penicillin, methicillin, and cephalosporins.[2] MRSA is especially troublesome in hospital-acquired (nosocomial) infections. In hospitals, patients with open wounds, invasive devices, and weakened

Bio Data (CV) of Dr. T. R. Shantha 29 Sunday, October 12, 2008 Page 29 of 37 immune systems are at greater risk and staff who do not follow proper sanitary procedures may inadvertently transfer bacterial colonies from patient to patient. 2. Developing a project to treat Human Papilloma Virus infection, which afflicts 30 million people in U.S.A alone? Has a patent for treating this condition. 3. Rabies is incurable. Seeking centers to study the effects of continuous hyperthermia combined with autoimmune therapy. It is believed that we can save at least 50% of these patients. 4. Treatment modalities of urine by using antiviral agents and urine antigens with gastric tube. 5. Treatment of Tuberculosis using hyperthermia and hyperbaric therapy and radiofrequency waves with nano anti tuberculosis agents. 6. Planning a project to study the effects of growth hormones and anabolic steroids in debilitated bedridden intensive care patients and post operative patients, and anabolic steroid use in advanced stage four cancers. 7. Treatment psoriasis, Lupus, Autoimmune diseases, eczema and many other systemic as well regional diseases of the by using multiple hyperthermia, hyperbaric therapy with low dose therapeutic agents and Insulin potentiation therapy along with autoimmune therapy are being explored. 8. Treatment of Interstitial cystitis using hyperthermia and Botox injection is being explored. At present there is no curative therapy. 9. To start projects to treat AIDS, ovarian cancer, PID, Endometriosis, Antibiotic resistant infections, pancreatic cancer, Colon cancer, prostate cancer with secondary deposits in the pelvic lymph node, Treatment of resistant Tuberculosis, AIDS, incurable diseases and infections, cancers, using hyperthermia, Hyperbaric therapy, IPT, antibiotic and chemotherapeutic agents as well use of continuous auto urine therapy through gastrostomy tube. 10. Development of devices to stimulate the hypothalamus and other parts of the nervous system through nerve tracks to relieve chronic pain, Alzheimer disease, addictions, mental problems and various other central nervous system diseases. The patent is received for the device and received and more patents are going to be applied.

Setting up cancer clinics using IPT, low and high dose anticancer agents (Metronomic therapy), Hyperthermia, Hyperbaric method etc. Establish also cancer prophylaxis and preventive clinics.

Research Presentation in the year 2004

Townsend letter: BEST OF NATUROPATHY IN 2004 – SLEEP LEFT SIDE DOWN (under preparation)

Bio Data (CV) of Dr. T. R. Shantha 30 Sunday, October 12, 2008 Page 30 of 37 Ft. Lauderdale, FL: HYPERBARIC OXYGENATION IN CP AND THE BRAIN-INJURED CHILD July 28-31, 2004

ICIM: INTERACTIONS AND ACTIONS OF NUTRITIONAL SUBSTANCES ON CANCERS, CHEMO THERAPY AND RADIATION. October 9, 2004

Ft. Lauderdale, FL: OXYGEN THERAPIES: HYPERBARIC OXYGEN (HBO-HBA), HYDROGEN PEROXIDE (H2O2) AND OZONE (O3) THERAPIES TO TREAT CANCERS AND OTHER DISEASES. Las Vegas: HYPERBARIC OXYGEN THERAPIES FOR ALL AGES

HYPERBARIC OXYGEN THERAPIES (HBO) FOR CANCERS AND OTHER INCURABLE DISEASES INCLUDING AGING

Research Presentation in the year 2005 -2006 Hyperbaric and Antiaging medical conferences about prolonging life and reduce ravages of aging and advanced cancers; In Las Vegas ACAM and anti Aging Seminar. 2007 -2009 [Important research paper Published in Life Extension by Dr. T. R. Shantha will save thousands from developing lung and oro-naso-pharyngeal tumors, cancer, asthma and other lung diseases. Probably culminated in withdrawal of inhalation insulin named Exubera form the market by Pfizer recently] 1. Latest: An important research article published on “Unknown Health Risks of Inhalation Insulin” By T. R. Shantha, MD, PhD, FACA, Life Extension, September 2007 issue in USA. This publication played a role in Pfizer withdrawing it Inhalation Insulin named Exubera, from the market in October 2007. Pfizer Pharmaceutical Company took a loss of 2.5 billion dollars. But, this action saved thousands of people developing cancers of respiratory, and oro – naso - pharyngeal system by its prolonged use with increase in Asthma etc; and future litigations amounting to billions by users. Received a letter from Glaxo Smith Kline Company supporting Dr. T. R. Shantha’s article. The drug companies will revise all inhalation insulin research in the light my recent research article. The copy of the letter from Glaxo is attached. I have sent my research article FDA offices and many drug companies which are trying to develop this dangerous mode of administration of Insulin. 2. T.R. Shantha, and Jessica G. Shantha: Inhalation Insulin and Oral and Nasal Insulin Sprays for Diabetics: Panacea or Evolving Future Health Disaster Part 1; Townsend Letter November-December #305, 2008, pages 94-98

Bio Data (CV) of Dr. T. R. Shantha 31 Sunday, October 12, 2008 Page 31 of 37 3. Part II; Townsend Letter January 2009 # 306, 2009, pages 9106-110 4. Histological demonstration of Pacinian corpuscles in dorsal and ventral roots of the spinal cord and their function ( under study since 1980s) 5. Treatment of Autism, Parkinson’s, Alzheimer, pain, and Rabies 6. Treatment of Alopecia and enhance Eye lid hair growth..

BOOKS BY T.R. SHANTHA

1. Shantha TR, Manocha SL and Bourne GH: A stereotaxic atlas of the brain of the java monkey (Macaca irus). S. Karger, Basel, Switzerland, 1967. 2. Manocha SL, Shantha TR and Bourne GH: A stereotaxic atlas of the brain of the cebus monkey (Cebus apella). Oxford University Press, London, 1967. 3. Tigges J and Shantha TR: A stereotaxic atlas of the brain of the tree shrew (Tupaia Glis). The Williams and Wilkins Co., Baltimore, 1968. 4. Manocha SL, Shantha TR and Bourne GH: Enzyme Histochemistry of the rhesus monkey brain (Macaca Mullatta). The Academic Press, New York, London, 1969. 5. Shantha TR: Your breast and its care. Fredric Fell Publishing Co., New York, 1974. 6. Shantha TR: AIDS-HIV: A prescription or survival. The International Publishing House, 1991. 7. Shantha TR and Bob Dowling etc. Cancercured.org, 2001 8. Books Under preparation for publication in the year 2008: a. Judas: (Devine Wind) Disciple, Apostle, Saint and First Christian Martyr; First Christian, and first Martyr (He was not a traitor or betrayer of Jesus as claimed. John Gospel tells us that Jesus says “18I speak not of you all: I know whom I have chosen”: Jesus further elaborates the chosen one among them to help him fulfill the scriptures. “12….but that the scripture may be fulfilled” John 13:18-30). Where is the betrayal here? Without Judas action, there would be no Christianity as we know now. In less than 24 hours, none other than Judas fulfilled 70% of the prophecies and predictions of Old Testament and contributed to resurrection of dead Jesus which is the central theme of Christianity) b. Jesus: Last 20 hours and 43 days of Jesus life are under preparation for publication. I have been researching and collecting pertinent material since 1978 for these two books. Hope to publish by spring of 2008. c. Jesus: Journey to Garden of Gethsemane:

First 5 books were published when Dr. Shantha was a faculty member in the Emory University School of Medicine, and Yerkes Regional Primate Research Center of Emory University School of Medicine, Atlanta. BOOKS UNDER RESEARCH AND PREPARATION 1. Sleep on left side and live longer 2. Hyperthermia and The Water with Life: Treatise on auto urine therapy to cure incurable diseases such as cancers, skin diseases, AIDS, leukemia, lupus, asthma, obesity, etc. 3. Breast Cancer, What Women Should Know, 2nd Ed.

Bio Data (CV) of Dr. T. R. Shantha 32 Sunday, October 12, 2008 Page 32 of 37 4. Cancer Busters: Prevention of cancers and living longer after cancer diagnosis. 5. IPT and its application for various chronic incurable diseases including cancers. 6. Cancer Book: What every one should know 7. MLK-American Gandhi

ARTICLES RELATED TO PUBLIC EDUCATION

Shantha TR: How to Live Long life. Tamil Nadu monthly magazine, a series of six articles (1988). Shantha TR: Political vendetta and don't nip us in the bud. Indian Express (April 20, 1989). Shantha TR: Women have same brain as men. News India, July 28, 1989. Shantha TR: Satish Chandra, scientist, and Harvard. News India (September 21, 1990). Shantha TR: Basavanna and Bible--about self-appointed, self-righteous people, Annual Issue of VSNA, Canadian edition (1992). Shantha TR: Let God, Let Go, VSNA Souvenir, 1994, Atlanta conference, 17th Annual Convention, page, 47 Shantha TR: sleep on the left side and keep the doctor away, VSNA Souvenir of the 18th Annual convention held at Baltimore, Maryland chapter, 1995 Shantha, TR: Sleep left side down and keep the doctors away, Inspirator International, Vol 11/1997, Edition 4/5, pages 24-28. Shantha, TR: Basavanna on Sinners and Their Salvation; VSNA Souvenir of the 21st Annual convention held at Washington DC hosted by Washington DC and Virginia chapters, 1999 Shantha T.R Jessica, Erica, Lauren T. Shantha, Usha Shantha Martin: Tribute to Mothers, Published in 3 magazines Khabar, Stone Mountain Signal, and Inspirator of Asia magazines and IACA magazine. May 1999. Shantha, T.R. Sarvagna, Confucius of India. VSNA publication 1997

ARTICLES UNDER PREPARATION

Shantha TR: The Relationship of Retro bulbar Local Anesthetic Spread to Neural Membranes of the Eyeball, Optic Nerve and Arachnoid Villi. Shantha TR and Bongiorno F: Intractable Gastrointestinal and Peritoneal Candida Infections: Treatment with Regional Peritoneal Hyperthermia. This was presented in hyperthermia congress in Destin Florida in the year 2000 +- Shantha TR: Subdural Intra-arachnoid Space: Its Use in Spinal Headache, Regional Anesthesia, and Pain. Shantha TR: Mechanism of Horner's Syndrome Resulting from Epidural, Caudal, Inter- costal, Inter-pleural and Sympathetic Nerve Blocks. Shantha TR et al: Use of Terbutaline to reduce bulging membranes during cerclage and facilitate Ureter - urethral stone passage with least pain. Shantha et al: Pacinian corpuscles in dorsal and ventral roots of the spinal cord and their function. Shantha TR- Treatment of Cataract, Glaucoma and other eye diseases using chelating antioxidant eye drops.

Bio Data (CV) of Dr. T. R. Shantha 33 Sunday, October 12, 2008 Page 33 of 37 Shantha TR-Treatment of Rabies using Ketamine, Sulfasalazine, oral anti rabies vaccine, Anti TNF, vaccines, IV lipids, administered under Hypoglycemia, Curcumin Shantha TR- Insulin potentiating effect of narcotics, steroids, antitumor necrosis factor – cytokine agents, and various diagnostic, therapeutic pharmacological, biologic and nutriceuticals preparations in epidural, inter spinous, olfactory regions.

Article since 2007

T.R.Shantha, MD, PhD, F.A.C.A Unknown Health Risks of Inhaled Insulin Life Extension, September 2007 pages 74-79, Post publication comments in September 2008, Pages 24

Inhalation Insulin, Oral and Nasal Insulin Sprays for Diabetics : Panacea or Evolving Future Health Disaster Part I T.R.Shantha, MD, PhD, F.A.C.A Jessica G. Shantha, Medical Student,; (Morehouse School of Medicine, Atlanta, Georgia); 115 Bayberry Hills, McDonough, GA 30253 Phone/Fax: 7 70-507-6564, Cell: 678-640-7705; Email: [email protected] Townsend Letter Journal: Issue #305, December 2008 pages: 94-98

Oral Insulin (swallowed) and Rectal Insulin Suppository for Diabetics: Panacea Or Evolving Future Health Disaster Part II will appear first quarter of 2009 in Townsend letter Journal T.R.Shantha, MD, PhD, F.A.C.A; Jessica G. Shantha, Medical Student, Morehouse School of Medicine, Atlanta; Founder and President of: “ONE MEAL ONE LIFE” foundation Townsend Letter, January, 2009, Issue # 306, pages -106-110

Oral, Rectal, and Spray Insulin for Diabetics Panacea Or Evolving Future Health Threat T.R. Shantha, MD, PhD, F.A.C.A Honorary Professor, JJM Medical College 115 Bayberry Hills, McDonough, GA 30253 Phone/Fax: 7 70-507-6564, Cell: 678-640-7705 Jessica G. Shantha, Second year medical student, Morehouse School of Medicine, Atlanta, GA Email: [email protected]; www.3e-tecnologies.com AAPI Journal. March Issue of 2009

Bio Data (CV) of Dr. T. R. Shantha 34 Sunday, October 12, 2008 Page 34 of 37 Abridged L ist of Dr.Shantha’s Research Contribution to Basic Science and Medicine

[ For his research discoveries extending over the period of 47 years in USA alone; he was awarded Distinguished Physician Award from AAPI which represents 42000 physician and Scientists in USA at their 23 Annual meeting at Houston Texas on June 19th of , 2005 and Professional Achievement Award from Veerashaiva Samaj Of North America (VSNA) which represents thousands of scientists, computer experts, physicians etc, which in turn represents more than 35 million Veerashaiva followers in India at their annual meeting held in Maryland on July 3rd of 2005. Dr. T. R. Shantha was nominated for Nobel Prize in Physiology and Medicine for the year 2007. Dr. T. R. Shantha’s latest research article published in September 2007on dangers of Inhalation Insulin in development of lung cancer and other catastrophic health conditions after prolonged use might have resulted (one of the reason) in withdrawal of inhalation Exubera by Pfizer with a loss of billions. This decision will save thousands of lives from morbidity and mortality. Many pharmaceutical companies which were in processes of developing this method of delivery of insulin are looking in to its long term effects and may stop further exploration and marketing due to Dr. T. R. Shantha’s research findings on this method of drug delivery]

Dr. T.R. Shantha has contributed immensely to basic medical science and finding therapies for many incurable health conditions. Dr. Shantha and Accidental Live Rabies Virus interjection during his research in collaboration with CDC of Atlanta: Important research event which almost cost his life. During his research work in collaboration with CDC of Atlanta, rabies center research division, he almost died of a rabies infection. The incidence of this deadly virus injection is as follows: Dr. Shantha was working in collaboration with the CDC in Atlanta, on the mechanisms of the rabies virus transfer to the central nervous system in the mid nineteen sixties. He went to the New Mexico Rabies Lab to conduct the experiments initiated by the CDC of Atlanta. While injecting the rabies virus under the microscope into the tiny nerves of the mice legs, he accidentally injected his left hand finger with the live rabies. He was immediately flown to Atlanta, inoculated with a duck anti-rabies vaccine at CDC. He survived the accidental injection of rabies virus infection. Out of this work, Dr. George Bear from CDC and Dr. Shantha published two research papers in the WHO Medical Journal which showed how fast the rabies virus is transmitted to the central nervous system and the role of nerve membranes on rabies virus transmission to the CNS. Due to duck anti-rabies vaccine he received, he developed severe autoimmune type allergic skin reaction. Even today he suffers from severe psoriatic type of allergic reaction on the skin. Perhaps, he is the only scientist on the record who survived the live fixed rabies virus injection in the annals of recent rabies research.

Selected Research contributions by Dr. Shantha along with Dr. G. H. Bourne from Emory University School Medicine Georgia Baptist Medical Center:

1. Dr. Shantha described pia- arachnoid mater of CNS extending as choroid of the eye through the fenestrated lamina cribrosa of the Optic Nerve. Dr. Shantha described the pia-arachnoid membrane of the Central Nervous System extending all the way to peripheral nerve endings

Bio Data (CV) of Dr. T. R. Shantha 35 Sunday, October 12, 2008 Page 35 of 37 except the naked pain fibers. He named it PERINEURAL EPITHELIUM. He was the first scientist from Emory to show that the onion ring like coverings of the Pacinian corpuscle is nothing but the extension of Pia-Arachnoid Mater of the central nervous system which is nothing but the Perineural epithelium. He along with Dr. G.H. Bourne demonstrated the origin of cells on the motor end plate and called it Peri -synaptic cells of the motor end plate. They are very important for proper functioning of the motor end plate and are derived from the perineural epithelium, so also are the cells of the capsule of the muscle spindles. The results of the report were published in Nature, Science, NEJM, J Anatomy (Lond), Anesthesiology, BJ of Anesthesia, J of Urology and other distinguished peer reviewed research journals all over the world. 2. Dr. Shantha showed the presence of Pacinian corpuscles on the Olfactory bulb which sub serve pressure sensation within the cranium and send messages of pressure in the brain. 3. Dr. Shantha showed that many layers of this epithelium surrounded the sympathetic chain of sperm whales. 4. Dr. Shantha demonstrated the presence of Arachnoid Villi in the optic nerve of man and other primates. Before this discovery, no one knew they existed in the optic nerve, where they serve a very important physiological function to maintain the normal function of the eye. He published 11 research papers on the eye alone. 5. Dr. Shantha and his colleagues showed the presence of intercellular pores in the corneal endothelium, which transmit nutrients to the vascular cornea. 6. Dr. Shantha demonstrated a double central canal in the spinal cord of normally functioning rats. 7. Dr. Shantha showed the presence of nerve ganglion cells far away from the spinal cord in the peroneal nerve of the feet. 8. Dr. Shantha published 12 papers on the Golgi complex of the entire CNS and eye. 9. Dr. Shantha developed a subarachnoid blood patch (not epidural blood patch) to stop CSF leakage and prevented seven surgeries on seven patients to exposed dura and patched the dura to prevent the CSF leak. This was published in the prestigious New England Journal of Medicine. 10. Dr. Shantha found Pacinian corpuscle in the Dorsal and ventral root of the spinal cord. This fact is often quoted in text books. 11. Dr. Shantha showed the presence of Arachnoid Villi in the dorsal and ventral spinal roots and their role in Epidural anesthesia. It is a 14 page paper and was published in the very distinguished journal Anesthesiology. This work is referenced in many text books. 12. Dr. Shantha developed a new method to block the occipital nerve for neuropathic pain and tension occipital headaches. 13. Dr. Shantha showed the presence of the Virchow –Robin space in peripheral nerves as seen in the CNS which plays an important role in the spread of local anesthetics in peripheral nerves. 14. Dr. Shantha showed the mechanisms of the action of LSD in the central nervous system. 15. Dr. Shantha wrote monographs on neurons (almost 300 pages), and chimpanzee brains (240 pages). 16. Dr. Shantha found a new simple drug for the treatment of PRIAPISM (painful persistent penile erection), which was published in the Journal of Urology and quoted in ER hand books and urology text books. Now this drug is used all over the world in Emergency Rooms for the above condition saving thousands of dollars in medical cost and preventing painful surgery to relieve the condition. He could have patented his discovery and made millions, which he did not. 17. Dr. Shantha developed and perfected a sub-cricoid retrograde method of intubations for difficult intubations which was published in the British Journal of Anesthesia. 18. Dr. Shantha developed three patents and is exploring their applications in Parkinson’s, Alzheimer’s, pain management, and various psychological illnesses. Now he has registered in

Bio Data (CV) of Dr. T. R. Shantha 36 Sunday, October 12, 2008 Page 36 of 37 Patent and trade mark office 7 applications on environmentally safe Energy efficient Electric bulbs and devices to prevent sudden infant death syndrome (SIDS) which can save thousands of children lives all over the world. 19. Dr. Shantha published four books on the Brain from Yerkes Primate Research Center of Emory University, a book on the breast and another one on AIDS. He is an expert on Urine therapy and is preparing a monograph. 20. Dr. Shantha was the first person to induce peritoneal hyperthermia in Georgia Baptist Hospital (now Atlanta Medical Center) for the treatment of massive terminal Candida infection of the peritoneal cavity and Septicemia. This can be used also to treat peritoneal cancer mets from the ovary, colon, and other cancers. The patient walked out and is still alive. He presented this paper during the International Hyperthermia Congress two years ago. 21. Four patients, who were previously bed ridden, have returned to work due to his method of treatment of Scleroderma. He presented these cases in a research meeting in Florida in the year 2005. 22. Dr. Shantha’s treatment using glucose facilitated therapy and others resulted in complete remission of lupus. 23. Many chronic Lyme disease patients who were disabled have gone back to work due to Dr. Shantha’s method of treatment. 24. Dr. Shantha’s research on new therapies in the treatment of cancers and other incurable diseases will continue. A local and systemic injection of cancer with anti-cancer agents, glucose and insulin, has opened a new method of treatment for cancers. The results have been very encouraging. (Glucose facilitated chemotherapy) 25. He is developing simple methods to prevent the death of children in cribs called SUDDEN INFANT DEATH SYNDROME (SIDS). He is applying for 3 patents (besides 3 patents he already has) on the subject, and when completed it will save the life of hundreds unfortunate babies who otherwise would die from SIDS. 26. He is the developer of Sleeping Left Side Down method to maintain good health, to prevent chronic diseases, reduce going to the doctors for illnesses, and to live longer. He published numerous reports on this subject and was well accepted and rewarded for those who practice this method. When time allows, he will publish a book. 27. Dr. Shantha has developed a method to prevent Hair Loss during chemotherapy. Early results have been very encouraging. He is applying for the patent and makes it available so that every child, woman and man who undergoes chemotherapy can use it without the fear loosing all the hairs. 28. Has conceived a new method to treat Cataract and various eye disease using local eye drops which I am applying for a patent. 29. Has developed treatment protocol for full blown rabies, which 100% fatal which is going to tried in south-east Asia.

Besides all other charitable works and contributions (including Morehouse Medical College Grady Memorial Hospital, Medical College of Georgia) Volunteering at Hands of Hope charity clinic in Henry county, GA which provides free medical care to hundreds of sick people who have no insurance and nor where to Gospels till 2005. Dr. Shantha also provided major funding and built a Girls High School in India (Hosadurga, Chitaldrug District) named after his father and mother, where 300 girls go to this wonderful high school since 1988 surrounded by clean environment and excellent teaching facilities. An estimated 2000 girls have graduated from this high school so far. He along with his other anesthesiologists in the group made large charity contribution through Medical Center Anesthesia Associated (MCAA) to build the Massive Hospital Tower Extension expansion of Georgia Baptist Medical center, which is now Atlanta Medical Center, located in the heart of Atlanta

Bio Data (CV) of Dr. T. R. Shantha 37 Sunday, October 12, 2008 Page 37 of 37