Fayetteville State University s8

Fayetteville State University College of Arts and Sciences Department of Biology BIOL 610 Endocrinology Fall 2014

I. Locator Information Instructor Dr. Stephen J. Salek Credit Hours 3.00 Course Location & Meeting Time: MW 4:00-5:50 LSA 130 Total Contact Hours 3.00 Office Hours TR 11-2, F 9-11 Office Location LSA 340 Office Telephone (use email**) (910) 672 -2103 E-mail [email protected]

Course Website: You must log on through FSU’s Blackboard Gateway @ http://blackboard.uncfsu.edu/. You will need your network login and password for access.

FSU Policy on Electronic Mail: Fayetteville State University provides to each student, free of charge, an electronic mail account that is easily accessible via the Internet. The university has established email as the primary mode of communicating with enrolled students about impending deadlines, upcoming events, and other information important to student progression at the university. Students are responsible for reading their email on a regular basis to remain aware of important information disseminated by the university. The university maintains open- use computer laboratories throughout the campus that can be used to access electronic mail. Students making inquiries via email to FSU faculty and staff about academic records, grades, bills, financial aid, and other matters of a confidential nature are required to use their FSU email account. Rules and regulations governing the use of FSU email may be found at: http://www.uncfsu.edu/PDFs/EmailPolicyFinal.pdf

II. COURSE DESCRIPTION A comprehensive study of Anatomy, physiology and function of endocrine glands in animals with particular emphasis on humans. This course will examine the current research on hormone related problems in humans such as the widespread effects of the stress response on physiological systems. Prerequisite: Undergraduate or graduate course in physiology and a willingness to put in plenty of study time. III. Disabled Student Services: In accordance with Section 504 of the 1973 Rehabilitation Act and the Americans with Disabilities Act (ACA) of 1990, if you have a disability or think you have a disability to please contact the Center for Personal Development in the Spaulding Building, (see “Submitting internet laboratory exercises” section below)

IV. TEXTBOOK 1. Endocrinology 6th edition M.E. Hadley (2000) ISBN 0-187606-6- 2. Why Zebras Don’t Get Ulcers. Robert M. Sapolsky (1998) ISBN 0-7167-3210-6 ** Text books can be purchased online at Barnes and Noble or Amazon.com, please order your books as soon as you decide to register for the class V. Student Learning Outcomes Upon successful completion of the course students will be able to 1. Describe the physiological mechanisms of hormone secretions and their actions. 3. Describe the results of hyper and hypo secretions of the hormones as they relate to human functions. 4. Describe the role of hormones in regulating the metabolism. 5. Compare endocrine control with nerve control of physiologic functions Understand hormone based effects of stress on body systems. VI. Course Requirements I grades Incompletes will be given in extraordinary circumstances only. In the event that an “I” is issued, the student must submit a list of all incomplete assessments by email. In addition, the student must research and indicate the date when the incomplete will be turned to an F if the work is not turned in. The instructor will reply confirming or correcting this list and date. When the work has been completed, the student must contact me via email and indicate when the work will be turned in. When we agree on a date and time, the student must submit all of the work at one time (by email). I will not grade any assessments that are turned in days, months, or weeks apart. All assignments must be completed by or before the date and time listed on the schedule page. These dates and times will be clearly stated in the syllabus and on the schedule page. I will not accept late work, and will issue a zero for all late work with the exceptions listed below (see “Tardy and Incomplete work”). All complaints and concerns should initially be made to me before bringing them to any other university employee. All students must send me an email stating that they agree to the terms in this syllabus.

ATTENDANCE AND WITHDRAWAL You are expected to complete all work. If you are not able to turn in your assignments during a particular week, they must be turned in prior to that week, not after that week. If you must withdraw from the course it is YOUR responsibility to complete the necessary paperwork for the withdrawal. If you stop completing assignments without officially withdrawing from the course, you will receive the grade earned based on your point total (at the time you stop attending) divided by the maximum points (as if you had completed ALL work). This usually means a grade of F will be recorded. If you do not interact with the course by 8/29/2014, you will be considered a no show (see below) and an interim grade if “X” will be entered. It is the student’s responsibility to carefully look at all due dates at the beginning of the semester and adjust their schedules to accommodate assessment deadlines.

Tardy and Incomplete work I do not accept late work without a reasonable excuse. Examples of reasonable excuses include unexpected illnesses accompanied by a doctor’s note, or the death of an immediate family member. If you submit your work after a due date , I will not read it unless you have provided a sanctioned excuse. Traveling to a location that has no internet connection will not be considered a valid excuse for incomplete work.

EVALUATION CRITERIA AND CLASS FORMAT Disclaimer: The instructor reserves the right to adjust any policy in this syllabus if it is deemed necessary. 1. You can expect me to show up on time and prepared for each class. I will lecture using powerpoint and leave time for discussion of the topic. I am willing to change the method of information delivery to meet your needs. You are expected to attend and prepare for each class by doing the assigned reading and printing out notes (when available) to write on during lecture.

2 I expect you to follow along in lecture by taking additional notes, asking and answering questions. You must bring your textbooks to each class.

2. ** During quizzes and exams, all personal materials (books, bags, purses, computers, phones) must be placed against the wall, placed in your car, or left home. I will only allow pens or pencils on your desk at this time.** 3. No texting, web surfing, facebook, twitter or using smartphones in class. I will allow course related use of electronic devices but if I find they are being used for purposes unrelated to class you will be asked to put them away. Any phone or computer use must be directly related to lecture. I am not opposed to you using them outside the lecture room if it does not disturb the class. Please remove any headphones before entering the lecture room. 4. Evaluation will be based mainly on the test scores. However, other components that are included in computing the final grade are presentations, class discussions and journal article summaries and class presentations. EXAMS Exams will contain a combination of true/false, matching, multiple choice, fill in the blanks, short and long essay questions. The instructor reserves the right to alter the exam format throughout the semester. I for some reason a makeup exam is given, the format and content will be at the instructor’s discretion. Makeup tests are not given without valid justification for missing the test. Student Led Class Activities Discussion Each student will lead a discussion on one chapter from Sapolski’s “Why Zebra’s Don’t Get Ulcers” The format of the discussion should include a typed out series of questions or exercises that generate discussion among students. Students may use up to 5 powerpoint slides to aid in the presentation of their discussion. Powerpoint presentation Give a short powerpoint presentation on a current peer reviewed journal article about current advances in endocrinology. A presentation should last at least 10 minutes but no longer than 20 minutes. Time should be made available for questions and discussion after each presentation. The topic must relate to a new advance in the field of endocrinology and relate to the topic covered in lecture that week.

Article reviews You will select two separate peer reviewed journal articles using the Science Direct database available through the campus library and complete a review for each. Each review will be worth 25 points. 1. The review will be done in the format of the article. You will submit a 2-4 page review for each article. 2. Create a title page containing the title of the article, the author’s names, your name, and the date. 3. Provide a written summary of the article by retyping each section of the article in an abbreviated format. 4. Retype the abstract, summarize the introduction, materials and methods, results into 2 paragraphs each. 5. Provide a written commentary on the discussion section similar to the article review you received for our example paper. This should include your overall evaluation of the article and highlighting what is useful, and what is lacking or needs improvement. 6. Re-type the five most useful references from the paper and the acknowledgements.

3 exams 300 points total Discussion 25 points Powerpoint presentation 25 points 2 article reviews 50 points

3 Final examination 100 points 500 total points

Grading Scale A = 92-100% B = 83-91% C = 73-82% F = < 73% REVISION OF GRADES – STUDENT RESPONSIBILITIES The following revisions became effective on August 16, 2007. WN GRADE DISCONTINUED:  WN - Withdrawal due to non-attendance - discontinued, effective August 16, 2007. STUDENTS: Do not expect faculty to withdraw you for non-attendance. Drop or withdraw* from classes according to the deadlines published in the catalog. *See warning below about class withdrawals. NEW TYPE OF GRADE: INTERIM GRADES – (New name for “midterm grade,” with additional purposes). Interim grades will be assigned from the first week of the semester until the deadline for class withdrawals. Interim grades are used for informational and warning purposes only; they are not part of your permanent transcript and have no effect on your GPA. Instructors may assign interim grade of F to warn students of poor academic performance or they may assign “X” or “EA” grades. (See below for explanations) After midterm, faculty will assign all students an interim grade of A – F to inform students of their academic status as of midterm.  INTERIM GRADE X = NO SHOW – Assigned to students who are on a class roster, but never attend class. For warning purposes only; NOT a final grade. STUDENTS: Check interim grades early in the semester. If you have an X grade, either begin attending the class or withdraw* from it. *See warning below about class withdrawals. If you do not take action in response to an X grade, you will receive a final grade of FN. (See “FN” below)  INTERIM GRADE EA = EXCESSIVE ABSENCES - Assigned to students whose class absences exceed 10% of the total contact hours. For warning purposes only, NOT a final grade. STUDENTS: Check your interim grades often. If you have an “EA” grade for a class, you are in jeopardy of failure if you do not take immediate actions. Either resume attending the class or withdraw from it. *See warning below about class withdrawals. NEW FINAL GRADE:  FN = FAILURE DUE TO NON-ATTENDANCE – Assigned to students who are on class roster, but never attend the class. An FN grades is equivalent to an F grade in the calculation of the GPA. STUDENTS: You must attend (or withdraw* from) all the classes for which you are enrolled. *See warning below about class withdrawals. WARNING ABOUT CLASS WITHDRAWALS:  When you withdraw from a class, you are wasting your money and time. You receive no refund for withdrawing from individual classes and you slow your progress toward degree completion.  If you withdraw from or fail more than one-third of your classes, you will no longer be eligible for financial aid.  STRIVE TO EARN CREDIT FOR ALL THE CLASSES IN WHICH YOU ENROLL; WITHDRAW FROM CLASSES ONLY WHEN IT IS ABSOLUTELY NECESSARY! Final Grades – This policy became effective on August 16, 2007 Grade Credit Hours Quality Points Meaning A Hours attempted and earned 4 per credit hour; Exceptionally high B Hours attempted and earned 3 per credit hour Good C Hours attempted and earned 2 per credit hour Satisfactory D Hours attempted and earned 1 per credit hour Marginally passing F Hours attempted – Not earned 0 per credit hour Failing FN Hours attempted – Not earned 0 per credit hour Failing due to non-attendance. (Student registered, but never attended.)

W Hours attempted – Not earned No impact on GPA Class withdrawal prior to deadline (see Academic Calendar) P Hours attempted and earned No impact on GPA Satisfactory - Assigned only in classes specified as Pass/Fail WU Hours attempted – Not earned No impact on GPA Withdrawal from all classes for semester or term AU Hours attempted – Not earned No impact on GPA Auditing

VII. Academic Support Resources Use the external links on your blackboard site. IX. TEACHING STRATEGIES A combination of instructor lectures, problem based discussions, student based discussions, and internet lectures. XI. Bibliography Books Guyton, A.C., Textbook of Medical Physiology, W.B. Saunders Publishers, Philadelphia, PA. (1996) Greenspan, Francis S., Basic and Clinical Endocrinology, Appleton and Lange Publishers (1994)

4 Journals Electronic journals and databases may be accessed through the Charles Chestnutt Library or through external links from our blackboard page: http://blackboard.uncfsu.edu/http://library.uncfsu.edu

Topic Readings Assignments Week

Week 1 M 8/18 No class W 8/20 Course introduction Selecting (3) journal articles Week 2 M 8/25 Introduction to Endocrinology Hadley Chapter 1 Select Sapolsky chapters W 8/27 Sapolsky Discussion Sapolsky Chapter 1 *Week 3 M 9/1 Labor day no class but read Hadley Chapter 2 W 9/3 The vertebrate endocrine system Hadley Chapter 2 Week 4 M 9/8 General mechanisms of action Hadley Chapter 3 Sapolsky discussion W 9/10 Sapolski Chapter 2 Article discussion Week 5 M 9/15 Endocrine methodologies Hadley Chapter 4 . Sapolsky discussion W 9/17 Sapolski Chapter 3 Article discussion Week 6

M 9/22 Pituitary Hormones Hadley Chapter 5

W 9/24 Exam 1 Ch. 1,2,3,4 and Sapolski Week 7

M 9/29 The endocrine hypothalamus Hadley Chapter 6

Sapolsky discussion W 10/1 Sapolski Chapter 9 Article discussion Week 8 M 10/6 Neurohypophyseal Hormones Hadley Chapter 7 Sapolsky discussion W 10/8 Salpolski Chapter 10 Article discussion *Week 9 M 10/13 Control of calcium homeostasis Hadley Chapter 9 W 10/15 Exam 2 Ch. 5,6,7 and Sapolski Week 10 M 10/20 Gastrointestinal hormones Hadley Chapter 10 Sapolsky discussion W 10/22 Salpolski Chapter 5 Journal article reviews due Article discussion Week 11 Pancreatic hormones and metabolic M 10/ 27 Hadley Chapter 11 regulation

5 Sapolsky discussion W 10/29 Sapolski Chapter 4 Article discussion Week 12 M 11/3 Growth hormones Hadley Chapter 12 Sapolsky discussion W 11/5 Sapolski Chapter 6 Article discussion Week 13 M 11/10 Thyroid hormones Hadley Chapter 13 W 11/12 Sapolski Chapter 11 Sapolsky discussion Week 14 Article discussion M 11/17 Catecholamines Hadley Chapter 14 W 11/19 Exam 3 Ch. 9,10,11 *Week 15 M 11/24 Reproductive hormones Hadley Chapters 17,18 Sapolsky discussion W 11/26 Sapolski Chapter 7 Article discussion Week 16 M 12/1 Neurohormones Hadley Chapter 21 Last Day of Class W 12/3 Sapolsky discussion Sapolski Chapter 8 Article discussion Graduating seniors take exams. Time to 12/4 be announced. Resolve all grading issues by 3 PM on 12/4. Week 17 Monday 12/8 4:00 -5:50 PM Final exam Final exam Ch 14, 17, 18 ,21 and Final exam Sapolski *** This is a tentative schedule. The text we are using is new, therefore the instructor reserves the right to alter the schedule at any time. It is your responsibility to be in class and check your blackboard page in order to keep pace with any changes made to the schedule or assignments.***