Organ Bath Pharmacology Workshop 2015

Date: 30 June & 1 July 2015 Venue: CP Snow, College Lane Campus, Hertfordshire University Speakers: Dr Louise Mackenzie Dr Mark Paul Clark Professor Gareth Sanger Dr David Bunton Dr John Broad Dr Lisa Lione Dr Chris Benham Dr Chris Keating

Administration: BPS office - [email protected]

Programme – Day 1

12:45 – 13:15 Registration and coffee Please note that lunch will not be provided on day 1

13:15 – 13:30 Introduction to Organ Bath Pharmacology Workshop Louise Mackenzie

13:30 – 14:30 The power of bioassay cascades; organ baths in series Mark Paul Clark

14:30 – 15:30 Translating cell-based functional studies using animal and human gastrointestinal tissues Gareth Sanger

15:30 – 15:45 Coffee

15:45 – 16:45 The use of Human tissue pharmacology in drug design David Bunton

16:45 – 17:15 The versatility of myographs Louise Mackenzie

17:15 – 17.45 Electrical Field Stimulation Chris Benham

17:45 End of day 1

19:00 Optional social event open to all delegates – workshop dinner Venue TBC

Programme – Day 2 08:30-09:00 Registration and coffee

09:00 – Computer Simulation of Guinea Pig Ileum and Data Analysis 10:45 Lisa Lione

These workshops will use a computer simulation of Guinea Pig Ileum contraction to acetylcholine, with and without atropine. Organ bath calculations will be completed as a group exercise and individuals will complete an organ bath simulation for processing of data and presentation on excel.

10:45 – Coffee break 11:15

11:15 – Final processing of simulation data 12:30 Lisa Lione

12:30 – Lunch 13:30

13:30 – Tour of labs and different types of organ bath in current usage for PhD 15:15 students

15:15 – Coffee 15:30

15:30 – The practicalities of obtaining and using human resections specimens for 16.30 pharmacological research John Broad

16:30- Measuring peristalsis in vitro 17:00 Chris Keating

17:00 Wrap up and close