Pharmacy 352, Principle of Pharmacy Practice

29 Pharmacy 721 Pharmacy Practice mEq practice calculations

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1. How many milligrams of potassium chloride are in two 8 mEq tablets of Klor-Con (KCl molecular weight = 74)?

2 x 8 mEq x 1 mmol x 74 mg = 1184 mg 1 mEq mmol

2. How many milliequivalents of sodium are in 1000 ml of 0.225% NaCl solution (molecular weight = 58)?

1000 ml x 0.225 g x 1000mg x 1 mmol x 1 mEq =38.8 mEq 100 ml 1 g 58 mg mmol

3. How many grams of NaCl are in 50 ml of a solution that contains 4.3 mEq/ml?

50 ml x 4.3 mEq x 1 mmol x 58 mg x 1 g =12.47 g ml 1 mEq mmol 1000 mg

4. How many milliequivalents of Ca++ are in 10 ml of a calcium gluconate (mw = 430) solution that contains 94 mg calcium gluconate per ml?

10 ml x 94 mg x 2 mEq x 1 mmol = 4.37 mEq ml mmol 430 mg

5. How many milliosmoles of dextrose are in 700 ml of a 70% dextrose solution (molecular weight = 180)?

700 ml x 70 g x 1000 mg x 1 mmol x 1 mOsm = 2722 mOsm 100 ml g 180 mg 1 mmol

6. How many milliosmoles are in 1 liter of a 0.45% NaCl solution (assume complete dissociation)?

1000 ml x 0.45 g x 1000 mg x 1 mmol x 2 mOsm = 155 mOsm 100 ml g 58 mg 1 mmol

7. Potassium chloride for injection comes in 60 ml vials containing 2 mEq/ml. How many milligrams of KCl are in each vial?

60 ml x 2 mEq x 1 mmol x 74 mg = 8880 mg ml 1 mEq 1 mmol

29 30 8. The antibiotic ampicillin sodium has 2.9 mEq Na+ per gram. If you prepare an IV with 2 grams of ampicillin in 100 ml NaCl solution, how many milliequivalents of sodium are in the IV?

2.9 mEq x 2 g = 5.8 mEq 1 g

100 ml x 0.9 g x 1000 mg x 1 mmol x 1 mEq = 15.5 mEq 100 ml g 58 mg 1 mmol

mEq Na+ in 2 gm ampicillin soudium_____5.8 mEq______

mEq Na+ in 100 ml 0.9% NaCl____15.5 mEq______

total mEq Na+__21.3 mEq______