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Common Eye Conditions Every Clinician Should Know

Cynthia S. Chiu, MD, FACS Associate Professor UCSF Department of

UCSF Board Review March 9, 2016 http://www.timandjeni.com/images/cookiemonster.jpg Disclosure

I have no financial interest in any of the products mentioned in this presentation The Eye Exam

 Eye Vital Sign  Near Vision Card  Held at 14 inches  Glasses as needed

http://www.drbanker.com/images/Nearvision.gif Pupils

 Look for afferent pupillary defect  Swinging flashlight test  +APD indicates optic nerve or large retinal lesion

http://img.tfd.com/ElMill/thumb/F0P-24-S2958.jpg Motility

 Six extraocular muscles  Test cardinal fields of gaze

http://www.opsweb.org/OpPhoto/Extern/Motility/muscle.jpg http://www.opsweb.org/OpPhoto/Extern/Motility/9gazedwg.jpg Confrontational Visual Fields

 Cover eyes on same side  Hold fingers midway between  Normal per eye: 60-60-60-90

http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=cm&part=A3460&rendertype=figure&id=A3464 Penlight Exam

Lids Lashes Conjunctiva/Sclera

Cornea

Iris/Pupil Puncta Lens

http://cache.heraldinteractive.com/blogs/sports/rap_sheet/wp-content/uploads/2009/11/bionic-eye.jpg Anterior Chamber Depth

 Deep chamber: illumination of nasal iris  Shallow chamber: shadow on nasal iris  Dilation: Phenylephrine 2.5%, Tropicamide 1%

http://iei.ico.edu/images/anatomy.jpg http://www.ophthobook.com/wp-content/uploads/2007/12/video-glaucoma-shallowpenlight.jpg Fundoscopy

 PanOptic or Direct Ophthalmoscope  Evaluate optic nerve, retinal vessels, macula

http://www.welchallyn.com/images/corporate/0509_wa_bmurf/011810xx1PanOpticRedHe.jpg http://webvision.med.utah.edu/imageswv/retina.jpeg Primary Care Ophthalmology

http://www.factzoo.com/sites/all/img/reptiles/chameleon-eyes.jpg The Red Eye

http://i.zdnet.com/blogs/lord-of-the-rings-ii-eye-of-sauron-4900244.jpg Viral Conjunctivitis

 URI  Clear or mucous discharge  Lymphadenopathy  Contagious!  Treat for comfort Bacterial Conjunctivitis

 Purulent discharge  Culture  Staph, Strep, Hflu – Polymixin/Trimethoprim – Fluoroquinolones – NOT Tobra or Gent  GC, chlamydia – Systemic Rx Allergic Conjunctivitis

 History of atopy  Conjunctival edema  Itchy!

 Topical antihistamines – Elestat – Zaditor – Patanol  Visine tachyphylaxis Blepharitis

 Redness, itching, “grit”, dry eyes  Rosacea, Staph, Demadex  Warm compresses, baby shampoo, artificial tears  Doxycycline, Azithromycin

http://www.stop-rosacea.com/ Herpes Simplex

 When to refer: V1, V2 red eye eye pain change in vision

 Acyclovir Herpes Zoster

 Hutchinson’s sign: nasociliary nerve  Treat Post-Herpetic Neuralgia: Lyrica, Neurontin, TCA’s

Uveitis

 Inflammation of vascular tissue  Auto-immune  Infectious  Toxic  Masquerade

 May require Angle Closure Glaucoma

 Headache  Loss of vision  Firm eye

 IV Diamox, Mannitol  Glaucoma gtt’s  Surgical treatment

Subconjunctival Hemorrhage

 Valsalva, HTN, anticoagulants, eye rubbing, spontaneous  In the setting of trauma: refer Corneal Abrasion

 Pain!  Loss of epithelium  Not infected

 Erythromycin ung  Artificial Tears  Patching Corneal Foreign Body

 Iron is toxic  Surgical treatment Hyphema

 Severe eye trauma  Risk of rebleed  Risk of glaucoma Ruptured Globe

 Peaked pupil  Brown tissue outside the eye  CT scan NOT MRI  Fox shield, NPO Common of Aging

http://www.jaredyellin.com/wp-content/uploads/2009/12/old-man-winking1.jpg Cataract

 Painless progressive loss of vision with age  Also caused by DM, XRT, trauma, medications  Difficulty reading, driving, glare  Outpatient Glaucoma

 Chronic progressive optic neuropathy  Loss of visual field  Risk factors: age, tobacco, race, family hx  Medications may have systemic interactions http://img.medscape.com/fullsize/migrated/569/545/569545.fig2.gif http://cdn.shopmedvet.com/images/uploads/2640_7780_thumb.jpg Macular Degeneration

 Risk factors: age, UV, tobacco, Family Hx  Loss of central vision  Dry form: AREDS vitamins, stop smoking  Wet form: anti-VEGF injections Disorders of the Eyelid and Orbit

http://greatpiercingshop.com/blog/wp-content/uploads/2009/12/eyelid-piercing-method-and-aftercare_49.jpg Chalazion

 Blocked oil gland  Inflammation

 Warm compresses  Incision/curettage Cellulitis

 Preseptal vs Orbital

 Preseptal: full EOM, no proptosis, quiet eye  Treat PO Abx

 Orbital: proptosis, strabismus, inflamed eye  Treat IV ABx Orbitopathy

 Proptosis  Strabismus/Diplopia  Corneal exposure  Optic nerve compression

 131-I may aggravate  Surgical treatment Disorders of the Retina

http://webphysics.davidson.edu/faculty/dmb/EdibleOpticalMaterials/index_files/cyclops.jpg Retinal Detachment

 Flashes/Floaters  Loss of vision/field  Sudden, painless

 Surgical treatment

http://www.rameshshahmd.com/pictures/retinal%20detach.%201.jpg?nxg_versionuid=published Diabetic Retinopathy

 Microvascular  Bleeding  Macular edema  Neovascularization

 Glucose/BP control  Laser ablation  Anti-VEGF

Hypertensive Retinopathy

 Mild: arteriolar narrowing  Mod: cotton wool spots, hemorrhages  Severe: disc edema, vessel leakage, infarcts HIV/CMV Retinopathy

 Microvascular disease  Annual exam if CD4>200  CMV retinitis

http://depts.washington.edu/hivaids/images/oit/oit_c7_d06.jpg Retinal Artery Occlusion

 Embolic: cardiac echo, carotid doppler  Vasculitic (GCA) Retinal Vein Occlusion

 Hypertension  Glaucoma  Young patients: hypercoagulable Neuro-Ophthalmology

http://www.capitalgainsmedia.com/images/Development%20News%20Photos/Dev-Ino-Issues%2002/Dev-Ino%20Issue%200244/DSC01869.jpg Stroke

 Homonymous field defect  Location of lesion is contralateral + upside-down Pituitary Adenoma

 Compression of nasal fibers at optic chiasm  Bitemporal hemianopia

http://www.lfhk.cuni.cz/patfyz/intranet/Figures/58/18.13.jpg Temporal Arteritis

 Acute vision loss

 Headache, jaw claudication, scalp tenderness, proximal myalgias, constitutional symptoms

 ESR and CRP  Prednisone 100mg QD  Temporal artery biopsy Optic Neuritis

 Loss of vision  Pain with EOM  +/- disc edema

 Multiple Sclerosis  Steroids

http://www.djo.harvard.edu/files/2982_355.jpg Pseudotumor Cerebri

 Headache, tinnitus  Papilledema  Vision loss

 Female, overweight  Medication-induced

 LP: opening pressure

http://www.caleyes.com/images/papilledema-image.jpg Horner Syndrome

 Anisocoria in the dark  Mild ptosis  Acute and painful: R/O carotid dissection

http://www.mrcophth.com/oculoplasticgallery/traumatichorner/horner.jpg Third Nerve Palsy

 Aniscoria in the light  Severe Ptosis  EOM paresis  Microvascular  PCA/PCom aneurysm

http://www.nature.com/eye/journal/v18/n3/images/6700625f1.jpg http://www.revophth.com/Images//2008/10/083_RPJ8_F6.gif Thank You!

http://blog.omy.sg/dingan/files/2009/05/bob.jpg References

 http://www.drgreene.com/21_1254.html  http://www.bobzyeruncle.com/archives/images/conjunctivitis-GC.html  http://www.ueseyecare.com/images/photos/allergic_conjunctivitis_l.jpg  http://www.ueseyecare.com/images/photos/viral_conjunctivitis_l.jpg  http://www.vigamox.com/images/packaging.jpg  http://dro.hs.columbia.edu/ced3/conjhemb.jpg  http://www.aafp.org/afp/20030401/1481_f3.jpg  http://eyemicrobiology.upmc.com/Images/Sub/PhotoEyeDendrite.jpg  http://www.hkmj.org.hk/skin/images/108-1.jpg  http://www.medicalskincare.be/images/content/herpes03.jpg  http://www.tusalud.com.mx/images/herpes_zoster.jpg  http://eyelearn.med.utoronto.ca/Lectures04-05/RedEye/images/11Kera2.jpg  http://www.nova.edu/~albert/ScleritisWeb.jpg  http://www.mrcophth.com/externaleyediseases/sp.JPG  http://e-learning.studmed.unibe.ch/augenheilkunde/systematik/aderhaut/images/iritis2.jpg  http://www.emedicine.com/oph/images/456cmv7.jpg  http://www.revoptom.com/handbook/images/62a.jpg  http://images.google.com/imgres?imgurl=http://www.asoprs.org/Graphics/gravesct.jpg&imgrefurl=http://www.asoprs.org/Pages/thyroid.html&h=250&w= 429&sz=9&tbnid=ul6zL-4JdFYJ:&tbnh=71&tbnw=122&start=1&prev=/images%3Fq%3Dthyroid%2Beye%2Bmuscles%26hl%3Den%26lr%3D  http://www.medscape.com/content/2002/00/44/63/446304/art-mop446304.coat.fig3.jpg  http://www.jeremydiamond.co.uk/graphics/cataract_eye.jpg  http://technology.kingston.ac.uk/dirc/medical/images/catara2.jpg  http://www.drloden.com/Pages/Pics/cataract.gif  http://www.eri.harvard.edu/faculty/peli/Opthalm_Mngt_0803_files/xNat.beauty.jpg  http://www.avclinic.com/images/tonometry.jpg  http://www.avclinic.com/Glaucoma.htm  http://www.lasikinstitute.org/Glaucoma_whatis.html  http://www.neec.com/images/photos/mitrev5.jpg  http://www.rvscny.com/images/Diabetic%20retinopathy.jpg  http://www.tedmontgomery.com/the_eye/eyephotos/pics/DiabeticRetinopathyProliferative.jpg  http://www.neec.com/images/photos/diabetic%20retinopathy%20figure%203.jpg

References

 http://www.gaileyeyeclinic.com/images/dr3.gif  http://www.foxeyecare.com/canon/large/diabetic_retinopathy.jpg  http://hubnet.buffalo.edu/ophthalmology/site/Home/Eye_Disorders/Hypertensive_retinopathy.jpg  http://www.mrcophth.com/retinacases/CMV.gif  http://www.opt.indiana.edu/ce/antseg/graphics/cwsaids.jpg  http://www.ohiovalleyeye.com/images/macdegen_K45_dry.jpg  http://www.opt.pacificu.edu/ce/catalog/10701-PS/4hemorr.jpg  http://www.ttuhsc.edu/eye/Faculty%20Presentations/Visual%20Field%20Testing%20Tech%20Seminar_files/slide0036_image002.jpg  http://webeye.ophth.uiowa.edu/dept/GCA/images/GCAfig1b_.jpg  http://www.ophthalmic.hyperguides.com/tutorials/oculoplastics/temporal_arteritis/slides/Slide1.jpg  http://www.mrcophth.com/pathology/gca2.jpg  http://content.lib.utah.edu/EHSL-WFH/image/icon124.jpg  http://www.atlasophthalmology.com/atlasimg/1396_6_low_thumb.jpg  http://www.tedmontgomery.com/the_eye/eyephotos/pics/CentralRetinalArteryOcclusion.jpg  http://www.omnieyespecialists.com/images/eye_brao.jpg  http://dro.hs.columbia.edu/vr3/crvob.jpg  http://www.scielo.br/img/revistas/abo/v66n6/18991f1.jpg  http://www.drugdigest.org/images/pillimages/A0315100.JPG  http://ec1.images-amazon.com/images/I/31ITYXvQYpL._AA200_.jpg  http://www.aafa.org/images/eye.jpg  http://www.aclens.com/accessoryphotos/visine-advanced-relief-eye-drops-15-6683-v3b.jpg  http://content.answers.com/main/content/wp/en-commons/thumb/6/69/420px-Gray784.png  http://eyelearn.med.utoronto.ca/Lectures02-03/RedEye/images/RedEye_033.jpg  http://www.varga.org/corneal_foreign_body_2.jpg  http://www.permanente.net/homepage/kaiser/pictures/7945.gif  http://www.medscape.com/pi/editorial/conferences/2001/747/art-aad-02.fig1.jpg  http://www.opt.pacificu.edu/ce/catalog/10310-SD/Trauma%20Pictures/Hyphema.jpg  http://www.revoptom.com/handbook/images/25aa.jpg  http://www.tedmontgomery.com/the_eye/eyephotos/pics/Chalazion.jpg  http://medicine.ucsd.edu/clinicalimg/eye-periorbital-cellulitis1.jpg  http://eyelearn.med.utoronto.ca/Lectures05-06/RedEye/images/RedEye_010.jpg